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    Wendy Jean Mack, PhD

    TitleProfessor of Preventive Medicine
    SchoolKeck School of Medicine of USC
    DepartmentPreventive Medicine
    AddressSSB 202Y 2001 N. Soto Street
    Health Sciences Campus
    Los Angeles California 90033
    Phone+1 323 442 1820
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      Collapse Overview
      Wendy Mack, PhD, is a professor of biostatistics in the Department of Preventive Medicine at the Keck School of Medicine of USC. She co-directs the department’s Division of Biostatistics graduate programs and directs Biostatistics Resources at the Southern California Clinical and Translational Science Institute (SC CTSI).

      Professor Mack has more than 20 years of experience directing biostatistical and data coordination activities, primarily funded by the National Institutes of Health (NIH). Her expertise includes design, conduct and analysis of multiple single-centered and multi-centered clinical trials and observational studies. She also directs biostatistical activities for the USC Alzheimer’s Disease Research Center and for other basic and clinical research programs.

      She has served on numerous NIH study sections for biostatistical expertise and has recently completed a term on the NHLBI Clinical Trials Review study section. Professor Mack received her doctorate from the University of Southern California. Her home is open to needy animals wandering by, and she dabbles in competitive dog obedience in her minimal spare time.

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Park SY, Love TMT, Reynell L, Yu C, Kang TM, Anastos K, DeHovitz J, Liu C, Kober KM, Cohen M, Mack W, Lee HY. The HIV Genomic Incidence Assay Meets False Recency Rate and Mean Duration of Recency Infection Performance Standards. Sci Rep. 2017 Aug 07; 7(1):7480. PMID: 28785052.
        View in: PubMed
      2. Aro AL, Reinier K, Rusinaru C, Uy-Evanado A, Darouian N, Phan D, Mack W, Jui J, Soliman EZ, Tereshchenko LG, Chugh SS. Electrical risk score beyond the left ventricular ejection fraction: prediction of sudden cardiac death in the Oregon Sudden Unexpected Death Study and the Atherosclerosis Risk in Communities Study. Eur Heart J. 2017 Jun 26. PMID: 28662567.
        View in: PubMed
      3. Mack W, Karim R. Reply To: Higher Intelligence and Later Maternal Age: Which Way Does the Causal Direction Go? J Am Geriatr Soc. 2017 Aug; 65(8):1885-1886. PMID: 28634984.
        View in: PubMed
      4. Desai S, Gruber PF, Eiting E, Seabury SA, Mack W, Voyageur C, Vasquez V, Kim HT, Terp S. The Effect of Utilization Review on Emergency Department Operations. Ann Emerg Med. 2017 May 27. PMID: 28559030.
        View in: PubMed
      5. Hanna DB, Lin J, Post WS, Hodis HN, Xue X, Anastos K, Cohen MH, Gange SJ, Haberlen SA, Heath SL, Lazar JM, Liu C, Mack W, Ofotokun I, Palella FJ, Tien PC, Witt MD, Landay AL, Kingsley LA, Tracy RP, Kaplan RC. Association of Macrophage Inflammation Biomarkers With Progression of Subclinical Carotid Artery Atherosclerosis in HIV-Infected Women and Men. J Infect Dis. 2017 May 01; 215(9):1352-1361. PMID: 28199691.
        View in: PubMed
      6. Yassine HN, Braskie MN, Mack W, Castor KJ, Fonteh AN, Schneider LS, Harrington MG, Chui HC. Association of Docosahexaenoic Acid Supplementation With Alzheimer Disease Stage in Apolipoprotein E e4 Carriers: A Review. JAMA Neurol. 2017 Mar 01; 74(3):339-347. PMID: 28114437.
        View in: PubMed
      7. Wei M, Brandhorst S, Shelehchi M, Mirzaei H, Cheng CW, Budniak J, Groshen S, Mack W, Guen E, Di Biase S, Cohen P, Morgan TE, Dorff T, Hong K, Michalsen A, Laviano A, Longo VD. Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Sci Transl Med. 2017 Feb 15; 9(377). PMID: 28202779.
        View in: PubMed
      8. Tatum JM, Bowdish ME, Mack W, Quinn AM, Cohen RG, Hackmann AE, Barr ML, Starnes VA. Outcomes after mitral valve repair: A single-center 16-year experience. J Thorac Cardiovasc Surg. 2017 Sep; 154(3):822-830.e2. PMID: 28283230.
        View in: PubMed
      9. Cleveland JD, Bowdish ME, Eberhardt CE, Mack W, Crabtree JA, Vassiliades TA, Speir AM, Darekar YA, Hackmann AE, Starnes VA, Cohen RG. Evaluation of Hemodynamic Performance of Aortic Valve Bioprostheses in a Model of Oversizing. Ann Thorac Surg. 2017 Jun; 103(6):1866-1876. PMID: 28131425.
        View in: PubMed
      10. Russell CJ, Mack W, Schrager SM, Wu S. Care Variations and Outcomes for Children Hospitalized With Bacterial Tracheostomy-Associated Respiratory Infections. Hosp Pediatr. 2017 01; 7(1):16-23. PMID: 27998905.
        View in: PubMed
      11. Alluri RK, Yin C, Iorio ML, Leland H, Mack W, Patel K. A Critical Appraisal of Vascularized Bone Grafting for Scaphoid Nonunion. J Wrist Surg. 2017 Aug; 6(3):251-257. PMID: 28725510.
        View in: PubMed
      12. Karim R, Dang H, Henderson VW, Hodis HN, St John J, Brinton RD, Mack W. Effect of Reproductive History and Exogenous Hormone Use on Cognitive Function in Mid- and Late Life. J Am Geriatr Soc. 2016 Dec; 64(12):2448-2456. PMID: 27996108.
        View in: PubMed
      13. Park SY, Mack W, Lee HY. Enhancement of viral escape in HIV-1 Nef by STEP vaccination. AIDS. 2016 Oct 23; 30(16):2449-2458. PMID: 27427874.
        View in: PubMed
      14. Lobo RA, Pickar JH, Stevenson JC, Mack W, Hodis HN. Back to the future: Hormone replacement therapy as part of a prevention strategy for women at the onset of menopause. Atherosclerosis. 2016 Nov; 254:282-290. PMID: 27745704.
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      15. Sharma A, Hoover DR, Shi Q, Holman S, Plankey MW, Wheeler AL, Weber K, Floris-Moore M, Bolivar HH, Vance DE, Mack W, Golub ET, Holstad MM, Yin MT. Falls among middle-aged women in the Women's Interagency HIV Study. Antivir Ther. 2016; 21(8):697-706. PMID: 27427794.
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      16. Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack W. Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis. Neurology. 2016 Aug 16; 87(7):699-708. PMID: 27421538; PMCID: PMC4999165 [Available on 08/16/17].
      17. Valcour VG, Rubin LH, Obasi MU, Maki PM, Peters MG, Levin S, Crystal HA, Young MA, Mack W, Cohen MH, Pierce CB, Adimora AA, Tien PC. Liver Fibrosis Linked to Cognitive Performance in HIV and Hepatitis C. J Acquir Immune Defic Syndr. 2016 Jul 01; 72(3):266-73. PMID: 26885801; PMCID: PMC4911304 [Available on 07/01/17].
      18. Yassine HN, Rawat V, Mack W, Quinn JF, Yurko-Mauro K, Bailey-Hall E, Aisen PS, Chui HC, Schneider LS. The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease. Alzheimers Res Ther. 2016 Jun 30; 8:25. PMID: 27358067; PMCID: PMC4928349.
      19. Park SY, Love TM, Perelson AS, Mack W, Lee HY. Molecular clock of HIV-1 envelope genes under early immune selection. Retrovirology. 2016 Jun 01; 13(1):38. PMID: 27246201; PMCID: PMC4888660.
      20. Breton CV, Yao J, Millstein J, Gao L, Siegmund KD, Mack W, Whitfield-Maxwell L, Lurmann F, Hodis H, Avol E, Gilliland FD. Prenatal Air Pollution Exposures, DNA Methyl Transferase Genotypes, and Associations with Newborn LINE1 and Alu Methylation and Childhood Blood Pressure and Carotid Intima-Media Thickness in the Children's Health Study. Environ Health Perspect. 2016 Dec; 124(12):1905-1912. PMID: 27219456.
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      21. Kurita K, Henderson VW, Gatz M, St John J, Hodis HN, Karim R, Mack W. Association of bilateral oophorectomy with cognitive function in healthy, postmenopausal women. Fertil Steril. 2016 Sep 01; 106(3):749-756.e2. PMID: 27183047.
        View in: PubMed
      22. Minejima E, Bensman J, She RC, Mack W, Tuan Tran M, Ny P, Lou M, Yamaki J, Nieberg P, Ho J, Wong-Beringer A. A Dysregulated Balance of Proinflammatory and Anti-Inflammatory Host Cytokine Response Early During Therapy Predicts Persistence and Mortality in Staphylococcus aureus Bacteremia. Crit Care Med. 2016 Apr; 44(4):671-9. PMID: 26540400.
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      23. Hodis HN, Mack W, Henderson VW, Shoupe D, Budoff MJ, Hwang-Levine J, Li Y, Feng M, Dustin L, Kono N, Stanczyk FZ, Selzer RH, Azen SP. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. N Engl J Med. 2016 Mar 31; 374(13):1221-31. PMID: 27028912; PMCID: PMC4921205 [Available on 09/30/16].
      24. Breton CV, Mack W, Yao J, Berhane K, Amadeus M, Lurmann F, Gilliland F, McConnell R, Hodis HN, Künzli N, Avol E. Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults. PLoS One. 2016; 11(3):e0150825. PMID: 26950592; PMCID: PMC4780745.
      25. Spencer LY, Christiansen S, Wang CH, Mack W, Young M, Strickler HD, Anastos K, Minkoff H, Cohen M, Geenblatt RM, Karim R, Operskalski E, Frederick T, Homans JD, Landay A, Kovacs A. Systemic Immune Activation and HIV Shedding in the Female Genital Tract. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):155-62. PMID: 26334738; PMCID: PMC4712091 [Available on 02/01/17].
      26. Kerzerho J, McIlvaine EJ, Anthony P, Mack W, Wang CH, Frederick T, Operskalski E, Chen Z, Al-Harthi L, Landay A, Young MA, Tien PC, Augenbraun M, Strickler HD, Akbari O, Golub ET, Sharp GB, Kovacs A. Impact of Hepatitis C Virus on the Circulating Levels of IL-7 in HIV-1 Coinfected Women. J Acquir Immune Defic Syndr. 2016 Feb 01; 71(2):172-80. PMID: 26761519; PMCID: PMC4712709 [Available on 02/01/17].
      27. Rettberg JR, Dang H, Hodis HN, Henderson VW, St John JA, Mack W, Brinton RD. Identifying postmenopausal women at risk for cognitive decline within a healthy cohort using a panel of clinical metabolic indicators: potential for detecting an at-Alzheimer's risk metabolic phenotype. Neurobiol Aging. 2016 Apr; 40:155-63. PMID: 26973115; PMCID: PMC4921204 [Available on 04/01/17].
      28. Zheng L, Vinters HV, Mack W, Weiner MW, Chui HC. Differential effects of ischemic vascular disease and Alzheimer's disease on brain atrophy and cognition. J Cereb Blood Flow Metab. 2016 Jan; 36(1):204-15. PMID: 26126864; PMCID: PMC4758550 [Available on 01/01/17].
      29. Love TM, Park SY, Giorgi EE, Mack W, Perelson AS, Lee HY. SPMM: estimating infection duration of multivariant HIV-1 infections. Bioinformatics. 2016 May 01; 32(9):1308-15. PMID: 26722117; PMCID: PMC4907399 [Available on 05/01/17].
      30. Reinier K, Narayanan K, Uy-Evanado A, Teodorescu C, Chugh H, Mack W, Gunson K, Jui J, Chugh SS. Electrocardiographic Markers and the Left Ventricular Ejection Fraction have Cumulative Effects on Risk of Sudden Cardiac Death. JACC Clin Electrophysiol. 2015 Dec 01; 1(6):542-550. PMID: 26949741.
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      31. Bauskar A, Mack W, Mauris J, Argüeso P, Heur M, Nagel BA, Kolar GR, Gleave ME, Nakamura T, Kinoshita S, Moradian-Oldak J, Panjwani N, Pflugfelder SC, Wilson MR, Fini ME, Jeong S. Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye. PLoS One. 2015; 10(9):e0138958. PMID: 26402857; PMCID: PMC4581869.
      32. Hajjar I, Wharton W, Mack W, Levey AI, Goldstein FC. Racial Disparity in Cognitive and Functional Disability in Hypertension and All-Cause Mortality. Am J Hypertens. 2016 Feb; 29(2):185-93. PMID: 26137951; PMCID: PMC4989127 [Available on 02/01/17].
      33. Baxi SM, Greenblatt RM, Bacchetti P, Jin C, French AL, Keller MJ, Augenbraun MH, Gange SJ, Liu C, Mack W, Gandhi M. Nevirapine Concentration in Hair Samples Is a Strong Predictor of Virologic Suppression in a Prospective Cohort of HIV-Infected Patients. PLoS One. 2015; 10(6):e0129100. PMID: 26053176; PMCID: PMC4460031.
      34. Brinton RD, Yao J, Yin F, Mack W, Cadenas E. Perimenopause as a neurological transition state. Nat Rev Endocrinol. 2015 Jul; 11(7):393-405. PMID: 26007613.
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      35. Hanna DB, Post WS, Deal JA, Hodis HN, Jacobson LP, Mack W, Anastos K, Gange SJ, Landay AL, Lazar JM, Palella FJ, Tien PC, Witt MD, Xue X, Young MA, Kaplan RC, Kingsley LA. HIV Infection Is Associated With Progression of Subclinical Carotid Atherosclerosis. Clin Infect Dis. 2015 Aug 15; 61(4):640-50. PMID: 25904369; PMCID: PMC4607734.
      36. Wecsler JS, Tereffe W, Pedersen RC, Sieffert MR, Mack W, Cui H, Russell CA, Woods RR, Viscusi RK, Sener SF, Lang JE. Lymph node status in inflammatory breast cancer. Breast Cancer Res Treat. 2015 May; 151(1):113-20. PMID: 25846421.
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      37. Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan TE, Finch CE, Pike CJ, Mack W, Cadenas E, Brinton RD. The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. Neurobiol Aging. 2015 Jul; 36(7):2282-2295. PMID: 25921624; PMCID: PMC4416218.
      38. Hodis HN, Mack W. Hormone therapy and risk of all-cause mortality in women treated with statins. Menopause. 2015 Apr; 22(4):363-4. PMID: 25756694.
        View in: PubMed
      39. Hodis HN, Mack W, Shoupe D, Azen SP, Stanczyk FZ, Hwang-Levine J, Budoff MJ, Henderson VW. Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis. Menopause. 2015 Apr; 22(4):391-401. PMID: 25380275; PMCID: PMC4376597.
      40. Bowdish ME, Hui DS, Cleveland JD, Mack W, Sinha R, Ranjan R, Cohen RG, Baker CJ, Cunningham MJ, Barr ML, Starnes VA. A comparison of aortic valve replacement via an anterior right minithoracotomy with standard sternotomy: a propensity score analysis of 492 patients. Eur J Cardiothorac Surg. 2016 Feb; 49(2):456-63. PMID: 25750007; PMCID: PMC4711701 [Available on 02/01/17].
      41. Valcour V, Rubin LH, Tien P, Anastos K, Young M, Mack W, Cohen M, Golub ET, Crystal H, Maki PM. Human immunodeficiency virus (HIV) modulates the associations between insulin resistance and cognition in the current combination antiretroviral therapy (cART) era: a study of the Women's Interagency HIV Study (WIHS). J Neurovirol. 2015 Aug; 21(4):415-21. PMID: 25740539; PMCID: PMC4511712.
      42. Jung M, Parrinello CM, Xue X, Mack W, Anastos K, Lazar JM, Selzer RH, Shircore AM, Plankey M, Tien P, Cohen M, Gange SJ, Hodis HN, Kaplan RC. Echolucency of the carotid artery intima-media complex and intima-media thickness have different cardiovascular risk factor relationships: the Women's Interagency HIV Study. J Am Heart Assoc. 2015 Feb 19; 4(2). PMID: 25699995; PMCID: PMC4345869.
      43. Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. JAMA Neurol. 2015 Feb; 72(2):209-16. PMID: 25531812; PMCID: PMC4324097.
      44. Yassine HN, Trenchevska O, He H, Borges CR, Nedelkov D, Mack W, Kono N, Koska J, Reaven PD, Nelson RW. Serum amyloid a truncations in type 2 diabetes mellitus. PLoS One. 2015; 10(1):e0115320. PMID: 25607823; PMCID: PMC4301920.
      45. Alexy T, Pais E, Wenby RB, Mack W, Hodis HN, Kono N, Wang J, Baskurt OK, Fisher TC, Meiselman HJ. Abnormal blood rheology and chronic low grade inflammation: possible risk factors for accelerated atherosclerosis and coronary artery disease in Lewis negative subjects. Atherosclerosis. 2015 Mar; 239(1):248-51. PMID: 25626016; PMCID: PMC4331217.
      46. Ahmadi N, Ruiz-Garcia J, Hajsadeghi F, Azen S, Mack W, Hodis H, Lerman A. Impaired coronary artery distensibility is an endothelium-dependent process and is associated with vulnerable plaque composition. Clin Physiol Funct Imaging. 2016 Jul; 36(4):261-8. PMID: 25524149.
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      47. Frazier DT, Seider T, Bettcher BM, Mack W, Jastrzab L, Chao L, Weiner MW, DeCarli C, Reed BR, Mungas D, Chui HC, Kramer JH. The role of carotid intima-media thickness in predicting longitudinal cognitive function in an older adult cohort. Cerebrovasc Dis. 2014; 38(6):441-7. PMID: 25502351; PMCID: PMC4303029.
      48. Karim R, Stanczyk FZ, Brinton RD, Rettberg J, Hodis HN, Mack W. Association of endogenous sex hormones with adipokines and ghrelin in postmenopausal women. J Clin Endocrinol Metab. 2015 Feb; 100(2):508-15. PMID: 25405497; PMCID: PMC4318897.
      49. Karim R, Mack W, Kono N, Tien PC, Anastos K, Lazar J, Young M, Desai S, Golub ET, Kaplan RC, Hodis HN, Kovacs A. T-cell activation, both pre- and post-HAART levels, correlates with carotid artery stiffness over 6.5 years among HIV-infected women in the WIHS. J Acquir Immune Defic Syndr. 2014 Nov 01; 67(3):349-56. PMID: 25314253; PMCID: PMC4197806.
      50. Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404. PMID: 25199842; PMCID: PMC4314944.
      51. Hajjar I, Hart M, Mack W, Lipsitz LA. Aldosterone, cognitive function, and cerebral hemodynamics in hypertension and antihypertensive therapy. Am J Hypertens. 2015 Mar; 28(3):319-25. PMID: 25213687; PMCID: PMC4402350.
      52. Frasco MA, Karim R, Van Den Berg D, Watanabe RM, Anastos K, Cohen M, Gange SJ, Gustafson DR, Liu C, Tien PC, Mack W, Pearce CL. Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women. AIDS. 2014 Jul 31; 28(12):1815-23. PMID: 24932614; PMCID: PMC4269472.
      53. Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, Mack W, Stohl W. Tear cathepsin S as a candidate biomarker for Sjögren's syndrome. Arthritis Rheumatol. 2014 Jul; 66(7):1872-81. PMID: 24644101; PMCID: PMC4077975.
      54. Villeneuve S, Reed BR, Madison CM, Wirth M, Marchant NL, Kriger S, Mack W, Sanossian N, DeCarli C, Chui HC, Weiner MW, Jagust WJ. Vascular risk and Aß interact to reduce cortical thickness in AD vulnerable brain regions. Neurology. 2014 Jul 01; 83(1):40-7. PMID: 24907234; PMCID: PMC4114172.
      55. St John JA, Henderson VW, Hodis HN, Kono N, McCleary CA, Franke AA, Mack W. Associations between urine excretion of isoflavonoids and cognition in postmenopausal women in the Women's Isoflavone Soy Health clinical trial. J Am Geriatr Soc. 2014 Apr; 62(4):629-35. PMID: 24617349; PMCID: PMC4226524.
      56. Mucowski SJ, Mack W, Shoupe D, Kono N, Paulson R, Hodis HN. Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women. Fertil Steril. 2014 Apr; 101(4):1117-22. PMID: 24530156; PMCID: PMC4215065.
      57. Reed B, Villeneuve S, Mack W, DeCarli C, Chui HC, Jagust W. Associations between serum cholesterol levels and cerebral amyloidosis. JAMA Neurol. 2014 Feb; 71(2):195-200. PMID: 24378418; PMCID: PMC4083819.
      58. Villeneuve S, Reed BR, Wirth M, Haase CM, Madison CM, Ayakta N, Mack W, Mungas D, Chui HC, DeCarli C, Weiner MW, Jagust WJ. Cortical thickness mediates the effect of ß-amyloid on episodic memory. Neurology. 2014 Mar 04; 82(9):761-7. PMID: 24489134; PMCID: PMC3945649.
      59. Hodis HN, Mack W. Response letter to Dr. Timo Strandberg. J Am Geriatr Soc. 2014 Jan; 62(1):206-7. PMID: 25180394.
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      60. Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Karim R, Shoupe D, Kono N, Dustin L, Allayee H, Mack W. Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5. PMID: 24277815; PMCID: PMC3864289.
      61. Gatto NM, Henderson VW, Hodis HN, St John JA, Lurmann F, Chen JC, Mack W. Components of air pollution and cognitive function in middle-aged and older adults in Los Angeles. Neurotoxicology. 2014 Jan; 40:1-7. PMID: 24148924; PMCID: PMC3946571.
      62. Halliday MR, Pomara N, Sagare AP, Mack W, Frangione B, Zlokovic BV. Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown. JAMA Neurol. 2013 Sep 01; 70(9):1198-200. PMID: 24030206; PMCID: PMC4047029.
      63. Quaas AM, Kono N, Mack W, Hodis HN, Felix JC, Paulson RJ, Shoupe D. Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial. Menopause. 2013 Aug; 20(8):840-4. PMID: 23422867; PMCID: PMC3934100.
      64. Zheng L, Vinters HV, Mack W, Zarow C, Ellis WG, Chui HC. Cerebral atherosclerosis is associated with cystic infarcts and microinfarcts but not Alzheimer pathologic changes. Stroke. 2013 Oct; 44(10):2835-41. PMID: 23887837; PMCID: PMC4049465.
      65. Hodis HN, Mack W. Hormone replacement therapy and the association with coronary heart disease and overall mortality: clinical application of the timing hypothesis. J Steroid Biochem Mol Biol. 2014 Jul; 142:68-75. PMID: 23851166.
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      66. Chao LL, Decarli C, Kriger S, Truran D, Zhang Y, Laxamana J, Villeneuve S, Jagust WJ, Sanossian N, Mack W, Chui HC, Weiner MW. Associations between white matter hyperintensities and ß amyloid on integrity of projection, association, and limbic fiber tracts measured with diffusion tensor MRI. PLoS One. 2013; 8(6):e65175. PMID: 23762308; PMCID: PMC3675157.
      67. Breton CV, Wang X, Mack W, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Response to letter regarding article, “Childhood air pollutant exposure and carotid artery intima–media thickness in young adults”. Circulation. 2013 Jun 04; 127(22):e659. PMID: 23882698; PMCID: PMC4035034.
      68. Karim R, Mack W, Stiller T, Operskalski E, Frederick T, Landay A, Young MA, Tien PC, Augenbraun M, Strickler HD, Kovacs A. Association of HIV clinical disease progression with profiles of early immune activation: results from a cluster analysis approach. AIDS. 2013 Jun 01; 27(9):1473-81. PMID: 23945505; PMCID: PMC3949252.
      69. Hodis HN, Mack W. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 2: comparative risks. J Am Geriatr Soc. 2013 Jun; 61(6):1011-8. PMID: 23692449.
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      70. Marchant NL, Reed BR, Sanossian N, Madison CM, Kriger S, Dhada R, Mack W, DeCarli C, Weiner MW, Mungas DM, Chui HC, Jagust WJ. The aging brain and cognition: contribution of vascular injury and aß to mild cognitive dysfunction. JAMA Neurol. 2013 Apr; 70(4):488-95. PMID: 23400560; PMCID: PMC3771392.
      71. Hajjar I, Brown L, Mack W, Chui H. Alzheimer pathology and angiotension receptor blockers. JAMA Neurol. 2013 Mar 01; 70(3):414. PMID: 23478841.
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      72. Hodis HN, Mack W. The timing hypothesis and hormone replacement therapy: a paradigm shift in the primary prevention of coronary heart disease in women. Part 1: comparison of therapeutic efficacy. J Am Geriatr Soc. 2013 Jun; 61(6):1005-10. PMID: 23414520; PMCID: PMC3660423.
      73. Karim R, Mack W, Kono N, Tien PC, Anastos K, Lazar J, Young M, Cohen M, Golub E, Greenblatt RM, Kaplan RC, Hodis HN. Gonadotropin and sex steroid levels in HIV-infected premenopausal women and their association with subclinical atherosclerosis in HIV-infected and -uninfected women in the women's interagency HIV study (WIHS). J Clin Endocrinol Metab. 2013 Apr; 98(4):E610-8. PMID: 23418313; PMCID: PMC3615203.
      74. Hajjar I, Hart M, Chen YL, Mack W, Novak V, C Chui H, Lipsitz L. Antihypertensive therapy and cerebral hemodynamics in executive mild cognitive impairment: results of a pilot randomized clinical trial. J Am Geriatr Soc. 2013 Feb; 61(2):194-201. PMID: 23350899; PMCID: PMC3608194.
      75. Dratva J, Breton CV, Hodis HN, Mack W, Salam MT, Zemp E, Gilliland F, Kuenzli N, Avol E. Birth weight and carotid artery intima-media thickness. J Pediatr. 2013 May; 162(5):906-11.e1-2. PMID: 23260106; PMCID: PMC4030536.
      76. Hajjar I, Brown L, Mack W, Chui H. Impact of Angiotensin receptor blockers on Alzheimer disease neuropathology in a large brain autopsy series. Arch Neurol. 2012 Dec; 69(12):1632-8. PMID: 22964777; PMCID: PMC3608189.
      77. Saremi A, Schwenke DC, Buchanan TA, Hodis HN, Mack W, Banerji M, Bray GA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Tripathy D, DeFronzo RA, Reaven PD. Pioglitazone slows progression of atherosclerosis in prediabetes independent of changes in cardiovascular risk factors. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):393-9. PMID: 23175674; PMCID: PMC3908828.
      78. Frasco MA, Mack W, Van Den Berg D, Aouizerat BE, Anastos K, Cohen M, De Hovitz J, Golub ET, Greenblatt RM, Liu C, Conti DV, Pearce CL. Underlying genetic structure impacts the association between CYP2B6 polymorphisms and response to efavirenz and nevirapine. AIDS. 2012 Oct 23; 26(16):2097-106. PMID: 22951632; PMCID: PMC3940150.
      79. Cardenas VA, Reed B, Chao LL, Chui H, Sanossian N, DeCarli CC, Mack W, Kramer J, Hodis HN, Yan M, Buonocore MH, Carmichael O, Jagust WJ, Weiner MW. Associations among vascular risk factors, carotid atherosclerosis, and cortical volume and thickness in older adults. Stroke. 2012 Nov; 43(11):2865-70. PMID: 22984010; PMCID: PMC3732460.
      80. Breton CV, Wang X, Mack W, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Künzli N, Avol E. Childhood air pollutant exposure and carotid artery intima-media thickness in young adults. Circulation. 2012 Sep 25; 126(13):1614-20. PMID: 22896588; PMCID: PMC3474843.
      81. Hajjar I, Mack W, Lipsitz L. Do Angiotensin receptor blockers really hold promise for the improvement of cognitive functioning?-Reply. Arch Intern Med. 2012 Aug 13; 172(15):1191-2. PMID: 23752873.
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      82. Zheng L, Teng EL, Varma R, Mack W, Mungas D, Lu PH, Chui HC. Chinese-language montreal cognitive assessment for cantonese or mandarin speakers: age, education, and gender effects. Int J Alzheimers Dis. 2012; 2012:204623. PMID: 22830073; PMCID: PMC3399373.
      83. Ryan J, Stanczyk FZ, Dennerstein L, Mack W, Clark MS, Szoeke C, Kildea D, Henderson VW. Hormone levels and cognitive function in postmenopausal midlife women. Neurobiol Aging. 2012 Jul; 33(7):1138-47. PMID: 22607736.
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      84. Jung S, Zarow C, Mack W, Zheng L, Vinters HV, Ellis WG, Lyness SA, Chui HC. Preservation of neurons of the nucleus basalis in subcortical ischemic vascular disease. Arch Neurol. 2012 Jul; 69(7):879-86. PMID: 22393167; PMCID: PMC4184885.
      85. Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8. PMID: 22722634; PMCID: PMC3398432.
      86. Villacres MC, Kono N, Mack W, Nowicki MJ, Anastos K, Augenbraun M, Liu C, Landay A, Greenblatt RM, Gange SJ, Levine AM. Interleukin 10 responses are associated with sustained CD4 T-cell counts in treated HIV infection. J Infect Dis. 2012 Sep 01; 206(5):780-9. PMID: 22693231; PMCID: PMC3491747.
      87. Gatto NM, Varma R, Torres M, Wong TY, Johnson PL, Segal-Gidan F, Mack W. Retinal microvascular abnormalities and cognitive function in Latino adults in Los Angeles. Ophthalmic Epidemiol. 2012 Jun; 19(3):127-36. PMID: 22568425; PMCID: PMC3598630.
      88. Homans J, Christensen S, Stiller T, Wang CH, Mack W, Anastos K, Minkoff H, Young M, Greenblatt R, Cohen M, Strickler H, Karim R, Spencer LY, Operskalski E, Frederick T, Kovacs A. Permissive and protective factors associated with presence, level, and longitudinal pattern of cervicovaginal HIV shedding. J Acquir Immune Defic Syndr. 2012 May 01; 60(1):99-110. PMID: 22517416; PMCID: PMC3334315.
      89. Hajjar I, Hart M, Chen YL, Mack W, Milberg W, Chui H, Lipsitz L. Effect of antihypertensive therapy on cognitive function in early executive cognitive impairment: a double-blind randomized clinical trial. Arch Intern Med. 2012 Mar 12; 172(5):442-4. PMID: 22412114; PMCID: PMC3536822.
      90. Zhao L, Morgan TE, Mao Z, Lin S, Cadenas E, Finch CE, Pike CJ, Mack W, Brinton RD. Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. PLoS One. 2012; 7(2):e31267. PMID: 22393359; PMCID: PMC3290616.
      91. Zheng L, Mack W, Chui HC, Heflin L, Mungas D, Reed B, DeCarli C, Weiner MW, Kramer JH. Coronary artery disease is associated with cognitive decline independent of changes on magnetic resonance imaging in cognitively normal elderly adults. J Am Geriatr Soc. 2012 Mar; 60(3):499-504. PMID: 22283410; PMCID: PMC3302932.
      92. Chui HC, Zheng L, Reed BR, Vinters HV, Mack W. Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review. Alzheimers Res Ther. 2012 Jan 04; 4(1):1. PMID: 22182734; PMCID: PMC3471388.
      93. Reed BR, Marchant NL, Jagust WJ, DeCarli CC, Mack W, Chui HC. Coronary risk correlates with cerebral amyloid deposition. Neurobiol Aging. 2012 Sep; 33(9):1979-87. PMID: 22078485; PMCID: PMC3371309.
      94. Karim R, Dell RM, Greene DF, Mack W, Gallagher JC, Hodis HN. Hip fracture in postmenopausal women after cessation of hormone therapy: results from a prospective study in a large health management organization. Menopause. 2011 Nov; 18(11):1172-7. PMID: 21775911; PMCID: PMC3511047.
      95. Crystal HA, Weedon J, Holman S, Manly J, Valcour V, Cohen M, Anastos K, Liu C, Mack W, Golub E, Lazar J, Ho A, Kreek MJ, Kaplan RC. Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women. J Neurovirol. 2011 Oct; 17(5):469-76. PMID: 22006469; PMCID: PMC3509940.
      96. Valcour V, Maki P, Bacchetti P, Anastos K, Crystal H, Young M, Mack W, Cohen M, Golub ET, Tien PC. Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study. AIDS Res Hum Retroviruses. 2012 May; 28(5):447-53. PMID: 21878059; PMCID: PMC3332367.
      97. Choudhury F, Bernstein L, Hodis HN, Stanczyk FZ, Mack W. Physical activity and sex hormone levels in estradiol- and placebo-treated postmenopausal women. Menopause. 2011 Oct; 18(10):1079-86. PMID: 21646925; PMCID: PMC3183237.
      98. Brommelhoff JA, Spann BM, Go JL, Mack W, Gatz M. Striatal Hypodensities, Not White Matter Hypodensities on CT, Are Associated with Late-Onset Depression in Alzheimer's Disease. J Aging Res. 2011; 2011:187219. PMID: 21949906; PMCID: PMC3178151.
      99. Schwartz RM, Mansoor A, Wilson TE, Anastos K, Everson-Rose SA, Golub ET, Goparaju L, Hessol NA, Mack W, Lazar J. Chronic depressive symptoms and Framingham coronary risk in HIV-infected and HIV-uninfected women. AIDS Care. 2012; 24(3):394-403. PMID: 21902560; PMCID: PMC3243818.
      100. Hodis HN, Mack W, Kono N, Azen SP, Shoupe D, Hwang-Levine J, Petitti D, Whitfield-Maxwell L, Yan M, Franke AA, Selzer RH. Isoflavone soy protein supplementation and atherosclerosis progression in healthy postmenopausal women: a randomized controlled trial. Stroke. 2011 Nov; 42(11):3168-75. PMID: 21903957; PMCID: PMC3202054.
      101. Baker JV, Henry WK, Patel P, Bush TJ, Conley LJ, Mack W, Overton ET, Budoff M, Hammer J, Carpenter CC, Hodis HN, Brooks JT. Progression of carotid intima-media thickness in a contemporary human immunodeficiency virus cohort. Clin Infect Dis. 2011 Oct; 53(8):826-35. PMID: 21860012; PMCID: PMC3174096.
      102. Franke AA, Lai JF, Halm BM, Pagano I, Kono N, Mack W, Hodis HN. Equol production changes over time in postmenopausal women. J Nutr Biochem. 2012 Jun; 23(6):573-9. PMID: 21775122; PMCID: PMC3901250.
      103. Breton CV, Wang X, Mack W, Berhane K, Lopez M, Islam TS, Feng M, Hodis HN, Künzli N, Avol E. Carotid artery intima-media thickness in college students: race/ethnicity matters. Atherosclerosis. 2011 Aug; 217(2):441-6. PMID: 21679950; PMCID: PMC3146627.
      104. Vigen CL, Mack W, Keefe RS, Sano M, Sultzer DL, Stroup TS, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Tariot PN, Zheng L, Schneider LS. Cognitive effects of atypical antipsychotic medications in patients with Alzheimer's disease: outcomes from CATIE-AD. Am J Psychiatry. 2011 Aug; 168(8):831-9. PMID: 21572163; PMCID: PMC3310182.
      105. Wahl SM, Redford M, Christensen S, Mack W, Cohn J, Janoff EN, Mestecky J, Jenson HB, Navazesh M, Cohen M, Reichelderfer P, Kovacs A. Systemic and mucosal differences in HIV burden, immune, and therapeutic responses. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):401-11. PMID: 21239996; PMCID: PMC3164950.
      106. Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack W, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41. PMID: 21460841; PMCID: PMC3090745.
      107. DeFronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Hodis HN, Kitabchi AE, Mack W, Mudaliar S, Ratner RE, Williams K, Stentz FB, Musi N, Reaven PD. Pioglitazone for diabetes prevention in impaired glucose tolerance. N Engl J Med. 2011 Mar 24; 364(12):1104-15. PMID: 21428766.
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      108. Ryan J, Stanczyk FZ, Dennerstein L, Mack W, Clark MS, Szoeke C, Kildea D, Henderson VW. Hormone levels and cognitive function in postmenopausal midlife women. Neurobiol Aging. 2012 Mar; 33(3):617.e11-22. PMID: 20888079.
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      109. Ryan J, Stanczyk FZ, Dennerstein L, Mack W, Clark MS, Szoeke C, Henderson VW. Executive functions in recently postmenopausal women: absence of strong association with serum gonadal steroids. Brain Res. 2011 Mar 16; 1379:199-205. PMID: 21050841.
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      110. Hodis HN, Mack W. A "window of opportunity:" the reduction of coronary heart disease and total mortality with menopausal therapies is age- and time-dependent. Brain Res. 2011 Mar 16; 1379:244-52. PMID: 20977895; PMCID: PMC3046231.
      111. Seaberg EC, Benning L, Sharrett AR, Lazar JM, Hodis HN, Mack W, Siedner MJ, Phair JP, Kingsley LA, Kaplan RC. Association between human immunodeficiency virus infection and stiffness of the common carotid artery. Stroke. 2010 Oct; 41(10):2163-70. PMID: 20798374; PMCID: PMC2972735.
      112. Karim R, Stanczyk FZ, Hodis HN, Cushman M, Lobo RA, Hwang J, Mack W. Associations between markers of inflammation and physiological and pharmacological levels of circulating sex hormones in postmenopausal women. Menopause. 2010 Jul; 17(4):785-90. PMID: 20632462; PMCID: PMC2907167.
      113. Franke AA, Hebshi SM, Pagano I, Kono N, Mack W, Hodis HN. Urine accurately reflects circulating isoflavonoids and ascertains compliance during soy intervention. Cancer Epidemiol Biomarkers Prev. 2010 Jul; 19(7):1775-83. PMID: 20615889; PMCID: PMC2950801.
      114. Kovacs A, Karim R, Mack W, Xu J, Chen Z, Operskalski E, Frederick T, Landay A, Voris J, Spencer LS, Young MA, Tien PC, Augenbraun M, Strickler HD, Al-Harthi L. Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus. J Infect Dis. 2010 Mar 15; 201(6):823-34. PMID: 20151840; PMCID: PMC3105602.
      115. Lavretsky H, Zheng L, Weiner MW, Mungas D, Reed B, Kramer JH, Jagust W, Chui H, Mack W. Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study. Am J Psychiatry. 2010 May; 167(5):589-97. PMID: 20160005; PMCID: PMC2864365.
      116. Segal-Gidan F, Varma R, Salazar X, Mack W. Factors influencing driving status in an older Latino population. J Aging Health. 2010 Apr; 22(3):332-47. PMID: 20142628; PMCID: PMC2896256.
      117. Künzli N, Jerrett M, Garcia-Esteban R, Basagaña X, Beckermann B, Gilliland F, Medina M, Peters J, Hodis HN, Mack W. Ambient air pollution and the progression of atherosclerosis in adults. PLoS One. 2010 Feb 08; 5(2):e9096. PMID: 20161713; PMCID: PMC2817007.
      118. Mueller SG, Mack W, Mungas D, Kramer JH, Cardenas-Nicolson V, Lavretsky H, Greene M, Schuff N, Chui HC, Weiner MW. Influences of lobar gray matter and white matter lesion load on cognition and mood. Psychiatry Res. 2010 Feb 28; 181(2):90-6. PMID: 20074914; PMCID: PMC2814971.
      119. Frederick T, Burian P, Terrault N, Cohen M, Augenbraun M, Young M, Seaberg E, Justman J, Levine AM, Mack W, Kovacs A. Factors associated with prevalent hepatitis C infection among HIV-infected women with no reported history of injection drug use: the Women's Interagency HIV Study (WIHS). AIDS Patient Care STDS. 2009 Nov; 23(11):915-23. PMID: 19877800; PMCID: PMC2823487.
      120. Karim R, Mack W, Hodis HN, Roy S, Stanczyk FZ. Influence of age and obesity on serum estradiol, estrone, and sex hormone binding globulin concentrations following oral estrogen administration in postmenopausal women. J Clin Endocrinol Metab. 2009 Nov; 94(11):4136-43. PMID: 19808850; PMCID: PMC2775642.
      121. Clark LJ, Gatz M, Zheng L, Chen YL, McCleary C, Mack W. Longitudinal verbal fluency in normal aging, preclinical, and prevalent Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2009 Dec-2010 Jan; 24(6):461-8. PMID: 19759254; PMCID: PMC2824246.
      122. Tien PC, Schneider MF, Cole SR, Cohen MH, Glesby MJ, Lazar J, Young M, Mack W, Hodis HN, Kaplan RC. Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study. AIDS. 2009 Aug 24; 23(13):1781-4. PMID: 19553807; PMCID: PMC2847440.
      123. Zheng L, Mack W, Dagerman KS, Hsiao JK, Lebowitz BD, Lyketsos CG, Stroup TS, Sultzer DL, Tariot PN, Vigen C, Schneider LS. Metabolic changes associated with second-generation antipsychotic use in Alzheimer's disease patients: the CATIE-AD study. Am J Psychiatry. 2009 May; 166(5):583-90. PMID: 19369318; PMCID: PMC2891018.
      124. Gatto NM, Henderson VW, St John JA, McCleary C, Detrano R, Hodis HN, Mack W. Subclinical atherosclerosis is weakly associated with lower cognitive function in healthy hyperhomocysteinemic adults without clinical cardiovascular disease. Int J Geriatr Psychiatry. 2009 Apr; 24(4):390-9. PMID: 18836986; PMCID: PMC2661006.
      125. St John JA, Henderson VW, Gatto NM, McCleary CA, Spencer CA, Hodis HN, Mack W. Mildly elevated TSH and cognition in middle-aged and older adults. Thyroid. 2009 Feb; 19(2):111-7. PMID: 19191743; PMCID: PMC2715222.
      126. Kapetanovic S, Christensen S, Karim R, Lin F, Mack W, Operskalski E, Frederick T, Spencer L, Stek A, Kramer F, Kovacs A. Correlates of perinatal depression in HIV-infected women. AIDS Patient Care STDS. 2009 Feb; 23(2):101-8. PMID: 19196032; PMCID: PMC2856494.
      127. Hodis HN, Mack W, Dustin L, Mahrer PR, Azen SP, Detrano R, Selhub J, Alaupovic P, Liu CR, Liu CH, Hwang J, Wilcox AG, Selzer RH. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke. 2009 Mar; 40(3):730-6. PMID: 19118243; PMCID: PMC2701290.
      128. Lavretsky H, Zheng L, Weiner MW, Mungas D, Reed B, Kramer JH, Jagust W, Chui H, Mack W. The MRI brain correlates of depressed mood, anhedonia, apathy, and anergia in older adults with and without cognitive impairment or dementia. Int J Geriatr Psychiatry. 2008 Oct; 23(10):1040-50. PMID: 18412291; PMCID: PMC2575050.
      129. Hodis HN, Mack W. Postmenopausal hormone therapy and cardiovascular disease in perspective. Clin Obstet Gynecol. 2008 Sep; 51(3):564-80. PMID: 18677151; PMCID: PMC2764865.
      130. Karim R, Hodis HN, Detrano R, Liu CR, Liu CH, Mack W. Relation of Framingham risk score to subclinical atherosclerosis evaluated across three arterial sites. Am J Cardiol. 2008 Oct 01; 102(7):825-30. PMID: 18805105; PMCID: PMC2648859.
      131. Gatto NM, Henderson VW, St John JA, McCleary C, Hodis HN, Mack W. Metabolic syndrome and cognitive function in healthy middle-aged and older adults without diabetes. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2008 Sep; 15(5):627-41. PMID: 18608045; PMCID: PMC2742696.
      132. Kovacs A, Al-Harthi L, Christensen S, Mack W, Cohen M, Landay A. CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus. J Infect Dis. 2008 May 15; 197(10):1402-7. PMID: 18444798; PMCID: PMC2443164.
      133. Hodis HN, Mack W. In Perspective: Estrogen Therapy Proves to Safely and Effectively Reduce Total Mortality and Coronary Heart Disease in Recently Postmenopausal Women. Menopause Manag. 2008 Mar; 17(2):27-32. PMID: 20490363.
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      134. Brinton RD, Thompson RF, Foy MR, Baudry M, Wang J, Finch CE, Morgan TE, Pike CJ, Mack W, Stanczyk FZ, Nilsen J. Progesterone receptors: form and function in brain. Front Neuroendocrinol. 2008 May; 29(2):313-39. PMID: 18374402; PMCID: PMC2398769.
      135. Operskalski EA, Mack W, Strickler HD, French AL, Augenbraun M, Tien PC, Villacres MC, Spencer LY, Degiacomo M, Kovacs A. Factors associated with hepatitis C viremia in a large cohort of HIV-infected and -uninfected women. J Clin Virol. 2008 Apr; 41(4):255-63. PMID: 18243785; PMCID: PMC3493623.
      136. Hodis HN, St John JA, Xiang M, Cushman M, Lobo RA, Mack W. Inflammatory markers and progression of subclinical atherosclerosis in healthy postmenopausal women (from the Estrogen in the Prevention of Atherosclerosis Trial). Am J Cardiol. 2008 Apr 15; 101(8):1131-3. PMID: 18394446.
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      137. Nowicki MJ, Vigen C, Mack W, Seaberg E, Landay A, Anastos K, Young M, Minkoff H, Greenblatt R, Levine AM. Association of cells with natural killer (NK) and NKT immunophenotype with incident cancers in HIV-infected women. AIDS Res Hum Retroviruses. 2008 Feb; 24(2):163-8. PMID: 18240964.
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      138. Jagust WJ, Zheng L, Harvey DJ, Mack W, Vinters HV, Weiner MW, Ellis WG, Zarow C, Mungas D, Reed BR, Kramer JH, Schuff N, DeCarli C, Chui HC. Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol. 2008 Jan; 63(1):72-80. PMID: 18157909; PMCID: PMC2624571.
      139. Khalsa A, Karim R, Mack W, Minkoff H, Cohen M, Young M, Anastos K, Tien PC, Seaberg E, Levine AM. Correlates of prevalent hypertension in a large cohort of HIV-infected women: Women's Interagency HIV Study. AIDS. 2007 Nov 30; 21(18):2539-41. PMID: 18025894.
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      140. Karim R, Hodis HN, Stanczyk FZ, Lobo RA, Mack W. Relationship between serum levels of sex hormones and progression of subclinical atherosclerosis in postmenopausal women. J Clin Endocrinol Metab. 2008 Jan; 93(1):131-8. PMID: 17925335; PMCID: PMC2190735.
      141. Hodis HN, Mack W. Estrogen therapy and coronary-artery calcification. N Engl J Med. 2007 Sep 20; 357(12):1252-3; author reply 1254. PMID: 17881758.
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      142. Kaplan RC, Kingsley LA, Sharrett AR, Li X, Lazar J, Tien PC, Mack W, Cohen MH, Jacobson L, Gange SJ. Ten-year predicted coronary heart disease risk in HIV-infected men and women. Clin Infect Dis. 2007 Oct 15; 45(8):1074-81. PMID: 17879928.
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      143. Gatto NM, Hodis HN, Liu CR, Liu CH, Mack W. Brachial artery vasoreactivity is associated with cross-sectional and longitudinal anatomical measures of atherosclerosis in postmenopausal women with coronary artery disease. Atherosclerosis. 2008 Feb; 196(2):674-81. PMID: 17803999; PMCID: PMC2693963.
      144. Hodis HN, Mack W. Postmenopausal hormone therapy in clinical perspective. Menopause. 2007 Sep-Oct; 14(5):944-57. PMID: 17353803.
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      145. Henderson SO, Simma-Chiang V, Lee C, Calder K, Mack W. Asthma: Effect of genotype on Response to Therapy in the Emergency Department. West J Emerg Med. 2007 Aug; 8(3):73-7. PMID: 19561686; PMCID: PMC2672218.
      146. Laskus T, Wilkinson J, Karim R, Mack W, Radkowski M, deGiacomo M, Nasseri J, Chen Z, Xu J, Kovacs A. Hepatitis C virus quasispecies in HIV-infected women: role of injecting drug use and highly active antiretroviral therapy (HAART). Hepatology. 2007 Aug; 46(2):359-70. PMID: 17659581; PMCID: PMC3508063.
      147. Mack W, Dhungana B, Dowsett SA, Keech CA, Feng M, Li Y, Hodis HN. Carotid artery intima-media thickness after raloxifene treatment. J Womens Health (Larchmt). 2007 Apr; 16(3):370-8. PMID: 17439382.
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      148. Steiner AZ, Xiang M, Mack W, Shoupe D, Felix JC, Lobo RA, Hodis HN. Unopposed estradiol therapy in postmenopausal women: results from two randomized trials. Obstet Gynecol. 2007 Mar; 109(3):581-7. PMID: 17329508.
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      149. Zheng L, Hodis HN, Buchanan TA, Li Y, Mack W. Effect of antihypertensive therapy on progression of carotid intima-media thickness in patients with type 2 diabetes mellitus. Am J Cardiol. 2007 Apr 01; 99(7):956-60. PMID: 17398191.
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      150. Nowicki MJ, Karim R, Mack W, Minkoff H, Anastos K, Cohen M, Greenblatt RM, Young MA, Gange SJ, Levine AM. Correlates of CD4+ and CD8+ lymphocyte counts in high-risk immunodeficiency virus (HIV)-seronegative women enrolled in the women's interagency HIV study (WIHS). Hum Immunol. 2007 May; 68(5):342-9. PMID: 17462501.
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      151. El-Shahawy M, Noureddin M, Abdullah H, Mack W, Calverley DC. Platelet FcgammaRIIA receptor surface expression is increased in patients with ESRD and is associated with atherosclerotic cardiovascular events. Am J Kidney Dis. 2007 Jan; 49(1):127-34. PMID: 17185153.
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      152. Chui HC, Zarow C, Mack W, Ellis WG, Zheng L, Jagust WJ, Mungas D, Reed BR, Kramer JH, Decarli CC, Weiner MW, Vinters HV. Cognitive impact of subcortical vascular and Alzheimer's disease pathology. Ann Neurol. 2006 Dec; 60(6):677-87. PMID: 17192928; PMCID: PMC1851933.
      153. Laskus T, Operskalski EA, Radkowski M, Wilkinson J, Mack W, deGiacomo M, Al-Harthi L, Chen Z, Xu J, Kovacs A. Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/HIV-infected women. J Infect Dis. 2007 Jan 01; 195(1):124-33. PMID: 17152016; PMCID: PMC3319123.
      154. Lin TC, Tintut Y, Lyman A, Mack W, Demer LL, Hsiai TK. Mechanical response of a calcified plaque model to fluid shear force. Ann Biomed Eng. 2006 Oct; 34(10):1535-41. PMID: 17006755.
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      155. Li X, Chu H, Gallant JE, Hoover DR, Mack W, Chmiel JS, Muñoz A. Bimodal virological response to antiretroviral therapy for HIV infection: an application using a mixture model with left censoring. J Epidemiol Community Health. 2006 Sep; 60(9):811-8. PMID: 16905728; PMCID: PMC2566033.
      156. Levine AM, Vigen C, Gravink J, Mack W, Watts CH, Liebman HA. Progressive prothrombotic state in women with advancing HIV disease. J Acquir Immune Defic Syndr. 2006 Aug 15; 42(5):572-7. PMID: 16837864.
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      157. Hodis HN, Mack W, Zheng L, Li Y, Torres M, Sevilla D, Stewart Y, Hollen B, Garcia K, Alaupovic P, Buchanan TA. Effect of peroxisome proliferator-activated receptor gamma agonist treatment on subclinical atherosclerosis in patients with insulin-requiring type 2 diabetes. Diabetes Care. 2006 Jul; 29(7):1545-53. PMID: 16801577.
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      158. Levine AM, Karim R, Mack W, Gravink DJ, Anastos K, Young M, Cohen M, Newman M, Augenbraun M, Gange S, Watts DH. Neutropenia in human immunodeficiency virus infection: data from the women's interagency HIV study. Arch Intern Med. 2006 Feb 27; 166(4):405-10. PMID: 16505259.
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      159. Andel R, Vigen C, Mack W, Clark LJ, Gatz M. The effect of education and occupational complexity on rate of cognitive decline in Alzheimer's patients. J Int Neuropsychol Soc. 2006 Jan; 12(1):147-52. PMID: 16433954.
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      160. Steiner AZ, Hodis HN, Lobo RA, Shoupe D, Xiang M, Mack W. Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Nov-Dec; 12(6):728-33. PMID: 16278616.
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      161. Meeske KA, Siegel SE, Globe DR, Mack W, Bernstein L. Prevalence and correlates of fatigue in long-term survivors of childhood leukemia. J Clin Oncol. 2005 Aug 20; 23(24):5501-10. PMID: 16110010.
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      162. Karim R, Mack W, Lobo RA, Hwang J, Liu CR, Liu CH, Sevanian A, Hodis HN. Determinants of the effect of estrogen on the progression of subclinical atherosclerosis: Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Jul-Aug; 12(4):366-73. PMID: 16037751.
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      163. Mack W, Teng E, Zheng L, Paz S, Chui H, Varma R. Category fluency in a latino sample: associations with age, education, gender, and language. J Clin Exp Neuropsychol. 2005 Jul; 27(5):591-8. PMID: 16019635.
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      164. Vigen C, Hodis HN, Selzer RH, Mahrer PR, Mack W. Relation of progression of coronary artery atherosclerosis to risk of cardiovascular events (from the Monitored Atherosclerosis Regression Study). Am J Cardiol. 2005 Jun 01; 95(11):1277-82. PMID: 15904629.
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      165. Lord SJ, Mack W, Van Den Berg D, Pike MC, Ingles SA, Haiman CA, Wang W, Parisky YR, Hodis HN, Ursin G. Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study. Breast Cancer Res. 2005; 7(3):R336-44. PMID: 15987428; PMCID: PMC1143576.
      166. Hwang J, Mack W, Xiang M, Sevanian A, Lobo RA, Hodis HN. Long-term effect of estrogen replacement on plasma nitric oxide levels: results from the estrogen in the prevention of atherosclerosis trial (EPAT). Atherosclerosis. 2005 Aug; 181(2):375-80. PMID: 16039293.
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      167. Künzli N, Jerrett M, Mack W, Beckerman B, LaBree L, Gilliland F, Thomas D, Peters J, Hodis HN. Ambient air pollution and atherosclerosis in Los Angeles. Environ Health Perspect. 2005 Feb; 113(2):201-6. PMID: 15687058; PMCID: PMC1277865.
      168. Calverley DC, Varteresian T, Brass E, Tsao-Wei DD, Groshen S, Mack W, Buchanan TA, Hodis HN, Schreiber AD. Association between monocyte Fcgamma subclass expression and acute coronary syndrome. Immun Ageing. 2004 Nov 12; 1(1):4. PMID: 15679933.
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      169. Henderson SO, Haiman CA, Mack W. Multiple Polymorphisms in the renin- angiotensin-aldosterone system (ACE, CYP11B2, AGTR1) and their contribution to hypertension in African Americans and Latinos in the multiethnic cohort. Am J Med Sci. 2004 Nov; 328(5):266-73. PMID: 15545843.
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      170. Krantz JS, Mack W, Hodis HN, Liu CR, Liu CH, Kaufman FR. Early onset of subclinical atherosclerosis in young persons with type 1 diabetes. J Pediatr. 2004 Oct; 145(4):452-7. PMID: 15480366.
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      171. Mack W, Slater CC, Xiang M, Shoupe D, Lobo RA, Hodis HN. Elevated subclinical atherosclerosis associated with oophorectomy is related to time since menopause rather than type of menopause. Fertil Steril. 2004 Aug; 82(2):391-7. PMID: 15302289.
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      172. Mack W, Preston-Martin S, Dal Maso L, Galanti R, Xiang M, Franceschi S, Hallquist A, Jin F, Kolonel L, La Vecchia C, Levi F, Linos A, Lund E, McTiernan A, Mabuchi K, Negri E, Wingren G, Ron E. A pooled analysis of case-control studies of thyroid cancer: cigarette smoking and consumption of alcohol, coffee, and tea. Cancer Causes Control. 2003 Oct; 14(8):773-85. PMID: 14674742.
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      173. Zheng L, Buchanan TA, Hodis HN, Li Y, Torres M, Mack W. Time from diagnosis of type 2 diabetes to initiation of insulin therapy is related to carotid artery intima-media thickness. Atherosclerosis. 2003 Oct; 170(2):293-9. PMID: 14612210.
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      174. Hodis HN, Mack W, Azen SP, Lobo RA, Shoupe D, Mahrer PR, Faxon DP, Cashin-Hemphill L, Sanmarco ME, French WJ, Shook TL, Gaarder TD, Mehra AO, Rabbani R, Sevanian A, Shil AB, Torres M, Vogelbach KH, Selzer RH. Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women. N Engl J Med. 2003 Aug 07; 349(6):535-45. PMID: 12904518.
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      175. Mack W, Islam T, Lee Z, Selzer RH, Hodis HN. Environmental tobacco smoke and carotid arterial stiffness. Prev Med. 2003 Aug; 37(2):148-54. PMID: 12855214.
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      176. Hodis HN, Mack W, Lobo RA. Randomized controlled trial evidence that estrogen replacement therapy reduces the progression of subclinical atherosclerosis in healthy postmenopausal women without preexisting cardiovascular disease. Circulation. 2003 Jul 08; 108(1):e5; author reply e5. PMID: 12847059.
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      177. Mack W, Hameed AB, Xiang M, Roy S, Slater CC, Stanczyk FZ, Lobo RA, Liu CR, Liu CH, Hodis HN. Does elevated body mass modify the influence of postmenopausal estrogen replacement on atherosclerosis progression: results from the estrogen in the prevention of atherosclerosis trial. Atherosclerosis. 2003 May; 168(1):91-8. PMID: 12732391.
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      178. Hodis HN, Mack W, Lobo R. What is the cardioprotective role of hormone replacement therapy? Curr Atheroscler Rep. 2003 Jan; 5(1):56-66. PMID: 12562544.
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      179. Hodis HN, Mack W, LaBree L, Mahrer PR, Sevanian A, Liu CR, Liu CH, Hwang J, Selzer RH, Azen SP. Alpha-tocopherol supplementation in healthy individuals reduces low-density lipoprotein oxidation but not atherosclerosis: the Vitamin E Atherosclerosis Prevention Study (VEAPS). Circulation. 2002 Sep 17; 106(12):1453-9. PMID: 12234947.
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      180. Sobel BE, Neimane D, Mack W, Hodis HN, Buchanan TA. The ratio of plasminogen activator inhibitor type-1 activity to the concentration of plasminogen activator inhibitor type-1 protein in diabetes: adding insult to injury. Coron Artery Dis. 2002 Aug; 13(5):275-81. PMID: 12394652.
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      181. Mack W, Preston-Martin S, Bernstein L, Qian D. Lifestyle and other risk factors for thyroid cancer in Los Angeles County females. Ann Epidemiol. 2002 Aug; 12(6):395-401. PMID: 12160598.
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      182. Hodis HN, Mack W, Lobo R. Antiatherosclerosis interventions in women. Am J Cardiol. 2002 Jul 03; 90(1A):17F-21F. PMID: 12106635.
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      183. Hodis HN, Mack W. Atherosclerosis imaging methods: assessing cardiovascular disease and evaluating the role of estrogen in the prevention of atherosclerosis. Am J Cardiol. 2002 Jun 20; 89(12A):19E-27E; discussion 27E. PMID: 12084399.
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      184. Hodis HN, Mack W, Lobo R. Postmenopausal hormone replacement therapy as antiatherosclerotic therapy. Curr Atheroscler Rep. 2002 Jan; 4(1):52-8. PMID: 11772423.
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