Joshua Millstein, PhD

Title(s)Associate Professor of Research Population and Public Health Sciences
SchoolKeck School of Medicine of Usc
AddressSSB 202N 2001 N. Soto Street
Health Sciences Campus
Los Angeles CA 90033
Phone+1 323 442 1450
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    Dr. Millstein’s research is focused on developing and applying statistical methods to address the many challenges of high dimensional data, particularly in multi-omic population-based studies of the genome, epigenome, transcriptome, microbiome, etc., in the context of pathogenesis of complex diseases such as cancer. With massive amounts of data collected in typical studies due to these advancing technologies, it has become increasingly important to have computational tools able to sift through all the information to separate the signal of interest from the noise. Specific areas of methods development include, causal mediation (CIT), dimensionality reduction, causal networks, false discovery rates (FDR), and epistasis/statistical interactions.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CausNet-partial : 'Partial Generational Orderings' based search for optimal sparse Bayesian networks via dynamic programming with parent set constraints. Res Sq. 2024 Mar 07. Sharma N, Millstein J. PMID: 38496505; PMCID: PMC10942557.
      View in: PubMed   Mentions:
    2. Predictive value of CDC37 gene expression for targeted therapy in metastatic colorectal cancer. Eur J Cancer. 2024 Apr; 201:113914. Arai H, Yang Y, Baca Y, Millstein J, Denda T, Ou FS, Innocenti F, Takeda H, Kubota Y, Doi A, Horie Y, Umemoto K, Izawa N, Wang J, Battaglin F, Jayachandran P, Algaze S, Soni S, Zhang W, Goldberg RM, Hall MJ, Scott AJ, Hwang JJ, Lou E, Weinberg BA, Marshall J, Goel S, Xiu J, Michael Korn W, Venook AP, Sunakawa Y, Lenz HJ. PMID: 38359495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value. J Immunother Cancer. 2024 01 11; 12(1). Battaglin F, Baca Y, Millstein J, Yang Y, Xiu J, Arai H, Wang J, Ou FS, Innocenti F, Mumenthaler SM, Jayachandran P, Kawanishi N, Lenz A, Soni S, Algaze S, Zhang W, Khoukaz T, Roussos Torres E, Seeber A, Abraham JP, Lou E, Philip PA, Weinberg BA, Shields AF, Goldberg RM, Marshall JL, Venook AP, Korn WM, Lenz HJ. PMID: 38212126; PMCID: PMC10806545.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Alzheimer's Related Neurodegeneration Mediates Air Pollution Effects on Medial Temporal Lobe Atrophy. medRxiv. 2023 Nov 29. Petkus AJ, Salminen LE, Wang X, Driscoll I, Millstein J, Beavers DP, Espeland MA, Braskie MN, Thompson PM, Casanova R, Gatz M, Chui HC, Resnick SM, Kaufman JD, Rapp SR, Shumaker S, Younan D, Chen JC. PMID: 38076972; PMCID: PMC10705654.
      View in: PubMed   Mentions:
    5. Association between late-life air pollution exposure and medial temporal lobe atrophy in older women. medRxiv. 2023 Nov 29. Wang X, Salminen LE, Petkus AJ, Driscoll I, Millstein J, Beavers DP, Espeland MA, Erus G, Braskie MN, Thompson PM, Gatz M, Chui HC, Resnick SM, Kaufman JD, Rapp SR, Shumaker S, Brown M, Younan D, Chen JC. PMID: 38077091; PMCID: PMC10705610.
      View in: PubMed   Mentions:
    6. Transcriptional Profiling and Consensus Molecular Subtype Assignment to Understand Response and Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Colorectal Cancer. JCO Precis Oncol. 2023 07; 7:e2200422. Chowdhury S, Gupta R, Millstein J, Lin K, Haridas V, Zeineddine MA, Parseghian C, Lenz HJ, Kopetz S, Shen JP. PMID: 37487150; PMCID: PMC10581628.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. ACDC: a general approach for detecting phenotype or exposure associated co-expression. Front Med (Lausanne). 2023; 10:1118824. Queen K, Nguyen MN, Gilliland FD, Chun S, Raby BA, Millstein J. PMID: 37275375; PMCID: PMC10235619.
      View in: PubMed   Mentions:
    8. CausNet: generational orderings based search for optimal Bayesian networks via dynamic programming with parent set constraints. BMC Bioinformatics. 2023 Feb 14; 24(1):46. Sharma N, Millstein J. PMID: 36788490; PMCID: PMC9926787.
      View in: PubMed   Mentions:    Fields:    
    9. Impact of genetic variants involved in the lipid metabolism pathway on progression free survival in patients receiving bevacizumab-based chemotherapy in metastatic colorectal cancer: a retrospective analysis of FIRE-3 and MAVERICC trials. EClinicalMedicine. 2023 Mar; 57:101827. Wang J, Millstein J, Yang Y, Stintzing S, Arai H, Battaglin F, Kawanishi N, Soni S, Zhang W, Mancao C, Cremolini C, Liu T, Heinemann V, Falcone A, Shen L, Lenz HJ. PMID: 36816347; PMCID: PMC9932345.
      View in: PubMed   Mentions:
    10. Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions. Oncogene. 2023 02; 42(9):627-637. Jayachandran P, Battaglin F, Strelez C, Lenz A, Algaze S, Soni S, Lo JH, Yang Y, Millstein J, Zhang W, Shih JC, Lu J, Mumenthaler SM, Spicer D, Neman J, Roussos Torres ET, Lenz HJ. PMID: 36650218; PMCID: PMC9957733.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study. Lancet Oncol. 2023 02; 24(2):151-161. Wang J, Xiu J, Farrell A, Baca Y, Arai H, Battaglin F, Kawanishi N, Soni S, Zhang W, Millstein J, Shields AF, Grothey A, Weinberg BA, Marshall JL, Lou E, Khushman M, Sohal DPS, Hall MJ, Liu T, Oberley M, Spetzler D, Korn WM, Shen L, Lenz HJ. PMID: 36681091; PMCID: PMC10599647.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    12. CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study. Cancer. 2023 03 01; 129(5):697-713. Kang EY, Weir A, Meagher NS, Farrington K, Nelson GS, Ghatage P, Lee CH, Riggan MJ, Bolithon A, Popovic G, Leung B, Tang K, Lambie N, Millstein J, Alsop J, Anglesio MS, Ataseven B, Barlow E, Beckmann MW, Berger J, Bisinotto C, Bösmüller H, Boros J, Brand AH, Brooks-Wilson A, Brucker SY, Carney ME, Casablanca Y, Cazorla-Jiménez A, Cohen PA, Conrads TP, Cook LS, Coulson P, Courtney-Brooks M, Cramer DW, Crowe P, Cunningham JM, Cybulski C, Darcy KM, El-Bahrawy MA, Elishaev E, Erber R, Farrell R, Fereday S, Fischer A, García MJ, Gayther SA, Gentry-Maharaj A, Gilks CB, AOCS Group, Grube M, Harnett PR, Harrington SP, Harter P, Hartmann A, Hecht JL, Heikaus S, Hein A, Heitz F, Hendley J, Hernandez BY, Polo SH, Heublein S, Hirasawa A, Høgdall E, Høgdall CK, Horlings HM, Huntsman DG, Huzarski T, Jewell A, Jimenez-Linan M, Jones ME, Kaufmann SH, Kennedy CJ, Khabele D, Kommoss FKF, Kruitwagen RFPM, Lambrechts D, Le ND, Lener M, Lester J, Leung Y, Linder A, Loverix L, Lubinski J, Madan R, Maxwell GL, Modugno F, Neuhausen SL, Olawaiye A, Olbrecht S, Orsulic S, Palacios J, Pearce CL, Pike MC, Quinn CM, Mohan GR, Rodríguez-Antona C, Ruebner M, Ryan A, Salfinger SG, Sasamoto N, Schildkraut JM, Schoemaker MJ, Shah M, Sharma R, Shvetsov YB, Singh N, Sonke GS, Steele L, Stewart CJR, Sundfeldt K, Swerdlow AJ, Talhouk A, Tan A, Taylor SE, Terry KL, Toloczko A, Traficante N, Van de Vijver KK, van der Aa MA, Van Gorp T, Van Nieuwenhuysen E, van-Wagensveld L, Vergote I, Vierkant RA, Wang C, Wilkens LR, Winham SJ, Wu AH, Benitez J, Berchuck A, Candido Dos Reis FJ, DeFazio A, Fasching PA, Goode EL, Goodman MT, Gronwald J, Karlan BY, Kommoss S, Menon U, Sinn HP, Staebler A, Brenton JD, Bowtell DD, Pharoah PDP, Ramus SJ, Köbel M. PMID: 36572991; PMCID: PMC10107112.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Neurotransmitter signaling: a new frontier in colorectal cancer biology and treatment. Oncogene. 2022 10; 41(43):4769-4778. Battaglin F, Jayachandran P, Strelez C, Lenz A, Algaze S, Soni S, Lo JH, Yang Y, Millstein J, Zhang W, Roussos Torres ET, Shih JC, Mumenthaler SM, Neman J, Lenz HJ. PMID: 36182970; PMCID: PMC10591256.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials. Eur J Cancer. 2022 09; 172:22-30. Wang J, Xiao Y, Loupakis F, Stintzing S, Yang Y, Arai H, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mancao C, Cremolini C, Liu T, Heinemann V, Falcone A, Shen L, Millstein J, Lenz HJ. PMID: 35749909.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. fdrci: FDR confidence interval selection and adjustment for large-scale hypothesis testing. Bioinform Adv. 2022; 2(1):vbac047. Millstein J, Battaglin F, Arai H, Zhang W, Jayachandran P, Soni S, Parikh AR, Mancao C, Lenz HJ. PMID: 35747247; PMCID: PMC9210923.
      View in: PubMed   Mentions: 4  
    16. Germline Polymorphisms in Genes Involved in the Antioxidant System Predict the Efficacy of Cetuximab in Metastatic Colorectal Cancer Patients Enrolled in FIRE-3 Trial. Clin Colorectal Cancer. 2022 09; 21(3):259-266. Arai H, Millstein J, Yang Y, Stintzing S, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Heinemann V, Lenz HJ. PMID: 35710481.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCellsCTClinical Trials
    17. Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study. PLoS Med. 2022 02; 19(2):e1003893. Younan D, Wang X, Millstein J, Petkus AJ, Beavers DP, Espeland MA, Chui HC, Resnick SM, Gatz M, Kaufman JD, Wellenius GA, Whitsel EA, Manson JE, Rapp SR, Chen JC. PMID: 35113870; PMCID: PMC8812844.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    18. Ambient air pollution exposure and increasing depressive symptoms in older women: The mediating role of the prefrontal cortex and insula. Sci Total Environ. 2022 Jun 01; 823:153642. Petkus AJ, Resnick SM, Wang X, Beavers DP, Espeland MA, Gatz M, Gruenewald T, Millstein J, Chui HC, Kaufman JD, Manson JE, Wellenius GA, Whitsel EA, Widaman K, Younan D, Chen JC. PMID: 35122843; PMCID: PMC8983488.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    19. Association of improved air quality with lower dementia risk in older women. Proc Natl Acad Sci U S A. 2022 01 11; 119(2). Wang X, Younan D, Millstein J, Petkus AJ, Garcia E, Beavers DP, Espeland MA, Chui HC, Resnick SM, Gatz M, Kaufman JD, Wellenius GA, Whitsel EA, Manson JE, Rapp SR, Chen JC. PMID: 34983871; PMCID: PMC8764698.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    20. MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma. Virchows Arch. 2022 Apr; 480(4):855-871. Kang EY, Millstein J, Popovic G, Meagher NS, Bolithon A, Talhouk A, Chiu DS, Anglesio MS, Leung B, Tang K, Lambie N, Pavanello M, Da-Anoy A, Lambrechts D, Loverix L, Olbrecht S, Bisinotto C, Garcia-Donas J, Ruiz-Llorente S, Yagüe-Fernandez M, Edwards RP, Elishaev E, Olawaiye A, Taylor S, Ataseven B, du Bois A, Harter P, Lester J, Høgdall CK, Armasu SM, Huang Y, Vierkant RA, Wang C, Winham SJ, Heublein S, Kommoss FKF, Cramer DW, Sasamoto N, van-Wagensveld L, Lycke M, Mateoiu C, Joseph J, Pike MC, Odunsi K, Tseng CC, Pearce CL, Bilic S, Conrads TP, Hartmann A, Hein A, Jones ME, Leung Y, Beckmann MW, Ruebner M, Schoemaker MJ, Terry KL, El-Bahrawy MA, Coulson P, Etter JL, LaVigne-Mager K, Andress J, Grube M, Fischer A, Neudeck N, Robertson G, Farrell R, Barlow E, Quinn C, Hettiaratchi A, Casablanca Y, Erber R, Stewart CJR, Tan A, Yu Y, Boros J, Brand AH, Harnett PR, Kennedy CJ, Nevins N, Morgan T, Fasching PA, Vergote I, Swerdlow AJ, Candido Dos Reis FJ, Maxwell GL, Neuhausen SL, Barquin-Garcia A, Modugno F, Moysich KB, Crowe PJ, Hirasawa A, Heitz F, Karlan BY, Goode EL, Sinn P, Horlings HM, Høgdall E, Sundfeldt K, Kommoss S, Staebler A, Wu AH, Cohen PA, DeFazio A, Lee CH, Steed H, Le ND, Gayther SA, Lawrenson K, Pharoah PDP, Konecny G, Cook LS, Ramus SJ, Kelemen LE, Köbel M. PMID: 34782936; PMCID: PMC9035053.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer. Oncogene. 2022 01; 41(2):260-267. Arai H, Elliott A, Millstein J, Xiu J, Ou FS, Innocenti F, Wang J, Battaglin F, Jayachandran P, Kawanishi N, Soni S, Zhang W, Sohal D, Goldberg RM, Hall MJ, Scott AJ, Khushman M, Hwang JJ, Lou E, Weinberg BA, Lockhart AC, Shields AF, Abraham JP, Magee D, Stafford P, Zhang J, Venook AP, Korn WM, Lenz HJ. PMID: 34728807; PMCID: PMC8738154.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. Germline polymorphisms in genes maintaining the replication fork predict the efficacy of oxaliplatin and irinotecan in patients with metastatic colorectal cancer. Br J Cancer. 2022 01; 126(1):72-78. Arai H, Xiao Y, Millstein J, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Parikh AR, Lenz HJ. PMID: 34689170; PMCID: PMC8727586.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    23. Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer. Oncogene. 2021 07; 40(30):4894-4905. Wang J, Xiu J, Baca Y, Battaglin F, Arai H, Kawanishi N, Soni S, Zhang W, Millstein J, Salhia B, Goldberg RM, Philip PA, Seeber A, Hwang JJ, Shields AF, Marshall JL, Astsaturov I, Craig Lockhart A, Gatalica Z, Michael Korn W, Lenz HJ. PMID: 34163031.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    24. Random survival forests identify pathways with polymorphisms predictive of survival in KRAS mutant and KRAS wild-type metastatic colorectal cancer patients. Sci Rep. 2021 06 09; 11(1):12191. Naseem M, Cao S, Yang D, Millstein J, Puccini A, Loupakis F, Stintzing S, Cremolini C, Tokunaga R, Battaglin F, Soni S, Berger MD, Barzi A, Zhang W, Falcone A, Heinemann V, Lenz HJ. PMID: 34108518; PMCID: PMC8190302.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Germ line polymorphisms of genes involved in pluripotency transcription factors predict efficacy of cetuximab in metastatic colorectal cancer. Eur J Cancer. 2021 06; 150:133-142. Arai H, Millstein J, Loupakis F, Stintzing S, Wang J, Battaglin F, Kawanishi N, Jayachandran P, Soni S, Zhang W, Mumenthaler SM, Cremolini C, Heinemann V, Falcone A, Lenz HJ. PMID: 33901792.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    26. Distinct genomic landscapes of gastroesophageal adenocarcinoma depending on PD-L1 expression identify mutations in RAS-MAPK pathway and TP53 as potential predictors of immunotherapy efficacy. Ann Oncol. 2021 07; 32(7):906-916. Wang JY, Xiu J, Baca Y, Arai H, Battaglin F, Kawanishi N, Soni S, Zhang W, Millstein J, Shields AF, Grothey A, Weinberg BA, Marshall JL, Lou E, Khushman M, Sohal DPS, Hall MJ, Oberley M, Spetzler D, Shen L, Korn WM, Lenz HJ. PMID: 33798656.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    27. RNA-Binding Protein Polymorphisms as Novel Biomarkers to Predict Outcomes of Metastatic Colorectal Cancer: A Meta-analysis from TRIBE, FIRE-3, and MAVERICC. Mol Cancer Ther. 2021 06; 20(6):1153-1160. Arai H, Cao S, Battaglin F, Wang J, Kawanishi N, Tokunaga R, Loupakis F, Stintzing S, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Cremolini C, Heinemann V, Falcone A, Millstein J, Lenz HJ. PMID: 33785650.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. The Landscape of Alterations in DNA Damage Response Pathways in Colorectal Cancer. Clin Cancer Res. 2021 06 01; 27(11):3234-3242. Arai H, Elliott A, Xiu J, Wang J, Battaglin F, Kawanishi N, Soni S, Zhang W, Millstein J, Sohal D, Goldberg RM, Hall MJ, Scott AJ, Khushman M, Hwang JJ, Lou E, Weinberg BA, Marshall JL, Lockhart AC, Stafford P, Zhang J, Moretto R, Cremolini C, Korn WM, Lenz HJ. PMID: 33766816.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    29. Prevalence and risk factors for cisplatin-induced hearing loss in children, adolescents, and young adults: a multi-institutional North American cohort study. Lancet Child Adolesc Health. 2021 04; 5(4):274-283. Moke DJ, Luo C, Millstein J, Knight KR, Rassekh SR, Brooks B, Ross CJD, Wright M, Mena V, Rushing T, Esbenshade AJ, Carleton BC, Orgel E. PMID: 33581749; PMCID: PMC9059427.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    30. Associations Between Air Pollution Exposure and Empirically Derived Profiles of Cognitive Performance in Older Women. J Alzheimers Dis. 2021; 84(4):1691-1707. Petkus AJ, Younan D, Wang X, Beavers DP, Espeland MA, Gatz M, Gruenewald T, Kaufman JD, Chui HC, Millstein J, Rapp SR, Manson JE, Resnick SM, Wellenius GA, Whitsel EA, Widaman K, Chen JC. PMID: 34744078; PMCID: PMC9057084.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    31. Lactose-reduced infant formula with added corn syrup solids is associated with a distinct gut microbiota in Hispanic infants. Gut Microbes. 2020 11 09; 12(1):1813534. Jones RB, Berger PK, Plows JF, Alderete TL, Millstein J, Fogel J, Iablokov SN, Rodionov DA, Osterman AL, Bode L, Goran MI. PMID: 32887539; PMCID: PMC7524300.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    32. Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer. J Immunother Cancer. 2020 11; 8(2). Arai H, Xiao Y, Loupakis F, Kawanishi N, Wang J, Battaglin F, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Weisenberger DJ, Liang G, Cremolini C, Falcone A, Millstein J, Lenz HJ. PMID: 33172883; PMCID: PMC7656952.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    33. Molecular Characterization of Appendiceal Goblet Cell Carcinoid. Mol Cancer Ther. 2020 12; 19(12):2634-2640. Arai H, Baca Y, Battaglin F, Kawanishi N, Wang J, Soni S, Zhang W, Millstein J, Johnston C, Goldberg RM, Philip PA, Seeber A, Xiu J, Hwang JJ, Shields AF, Marshall JL, Korn WM, Lenz HJ. PMID: 33037134; PMCID: PMC8011958.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. Are Epithelial Ovarian Cancers of the Mesenchymal Subtype Actually Intraperitoneal Metastases to the Ovary? Front Cell Dev Biol. 2020; 8:647. Hu Y, Taylor-Harding B, Raz Y, Haro M, Recouvreux MS, Taylan E, Lester J, Millstein J, Walts AE, Karlan BY, Orsulic S. PMID: 32766252; PMCID: PMC7380132.
      View in: PubMed   Mentions: 11  
    35. Correction to: Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study. Cancer Causes Control. 2020 06; 31(6):607. Wadé NB, Chang CM, Conti D, Millstein J, Skibola C, Nieters A, Wang SS, De Sanjose S, Kane E, Spinelli JJ, Bracci P, Zhang Y, Slager S, Wang J, Hjalgrim H, Smedby KE, Brown EE, Jarrett RF, Cozen W, InterLymph Consortium Immunology and Infection Working Group. PMID: 32227299.
      View in: PubMed   Mentions:    Fields:    
    36. Prognostic gene expression signature for high-grade serous ovarian cancer. Ann Oncol. 2020 09; 31(9):1240-1250. Millstein J, Budden T, Goode EL, Anglesio MS, Talhouk A, Intermaggio MP, Leong HS, Chen S, Elatre W, Gilks B, Nazeran T, Volchek M, Bentley RC, Wang C, Chiu DS, Kommoss S, Leung SCY, Senz J, Lum A, Chow V, Sudderuddin H, Mackenzie R, George J, AOCS Group, Fereday S, Hendley J, Traficante N, Steed H, Koziak JM, Köbel M, McNeish IA, Goranova T, Ennis D, Macintyre G, Silva De Silva D, Ramón Y Cajal T, García-Donas J, Hernando Polo S, Rodriguez GC, Cushing-Haugen KL, Harris HR, Greene CS, Zelaya RA, Behrens S, Fortner RT, Sinn P, Herpel E, Lester J, Lubinski J, Oszurek O, Toloczko A, Cybulski C, Menkiszak J, Pearce CL, Pike MC, Tseng C, Alsop J, Rhenius V, Song H, Jimenez-Linan M, Piskorz AM, Gentry-Maharaj A, Karpinskyj C, Widschwendter M, Singh N, Kennedy CJ, Sharma R, Harnett PR, Gao B, Johnatty SE, Sayer R, Boros J, Winham SJ, Keeney GL, Kaufmann SH, Larson MC, Luk H, Hernandez BY, Thompson PJ, Wilkens LR, Carney ME, Trabert B, Lissowska J, Brinton L, Sherman ME, Bodelon C, Hinsley S, Lewsley LA, Glasspool R, Banerjee SN, Stronach EA, Haluska P, Ray-Coquard I, Mahner S, Winterhoff B, Slamon D, Levine DA, Kelemen LE, Benitez J, Chang-Claude J, Gronwald J, Wu AH, Menon U, Goodman MT, Schildkraut JM, Wentzensen N, Brown R, Berchuck A, Chenevix-Trench G, deFazio A, Gayther SA, García MJ, Henderson MJ, Rossing MA, Beeghly-Fadiel A, Fasching PA, Orsulic S, Karlan BY, Konecny GE, Huntsman DG, Bowtell DD, Brenton JD, Doherty JA, Pharoah PDP, Ramus SJ. PMID: 32473302; PMCID: PMC7484370.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    37. partition: A fast and flexible framework for data reduction in R. J Open Source Softw. 2020; 5(47). Barrett M, Millstein J. PMID: 35265788; PMCID: PMC8903188.
      View in: PubMed   Mentions: 1  
    38. Association of HLA Genotype With T-Cell Activation in Human Immunodeficiency Virus (HIV) and HIV/Hepatitis C Virus-Coinfected Women. J Infect Dis. 2020 03 16; 221(7):1156-1166. Kovacs AAZ, Kono N, Wang CH, Wang D, Frederick T, Operskalski E, Tien PC, French AL, Minkoff H, Kassaye S, T Golub E, Aouizerat BE, Kuniholm MH, Millstein J. PMID: 31802115; PMCID: PMC7325713.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Infectious mononucleosis, immune genotypes, and non-Hodgkin lymphoma (NHL): an InterLymph Consortium study. Cancer Causes Control. 2020 05; 31(5):451-462. Wadé NB, Chang CM, Conti D, Millstein J, Skibola C, Nieters A, Wang SS, De Sanjose S, Kane E, Spinelli JJ, Bracci P, Zhang Y, Slager S, Wang J, Hjalgrim H, Smedby KE, Brown EE, Jarrett RF, Cozen W, InterLymph Consortium Immunology and Infection Working Group. PMID: 32124188; PMCID: PMC7534692.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    40. Partition: a surjective mapping approach for dimensionality reduction. Bioinformatics. 2020 02 01; 36(3):676-681. Millstein J, Battaglin F, Barrett M, Cao S, Zhang W, Stintzing S, Heinemann V, Lenz HJ. PMID: 31504178; PMCID: PMC8215926.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    41. High intake of dietary fructose in overweight/obese teenagers associated with depletion of Eubacterium and Streptococcus in gut microbiome. Gut Microbes. 2019; 10(6):712-719. Jones RB, Alderete TL, Kim JS, Millstein J, Gilliland FD, Goran MI. PMID: 30991877; PMCID: PMC6866686.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    42. AMPK variant, a candidate of novel predictor for chemotherapy in metastatic colorectal cancer: A meta-analysis using TRIBE, MAVERICC and FIRE3. Int J Cancer. 2019 10 15; 145(8):2082-2090. Tokunaga R, Cao S, Naseem M, Battaglin F, Lo JH, Arai H, Loupakis F, Stintzing S, Puccini A, Berger MD, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Weisenberger DJ, Liang G, Cremolini C, Heinemann V, Falcone A, Millstein J, Lenz HJ. PMID: 30856283; PMCID: PMC7491977.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    43. Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3. Eur J Cancer. 2019 04; 111:138-147. Puccini A, Loupakis F, Stintzing S, Cao S, Battaglin F, Togunaka R, Naseem M, Berger MD, Soni S, Zhang W, Mancao C, Salhia B, Mumenthaler SM, Weisenberger DJ, Liang G, Cremolini C, Heinemann V, Falcone A, Millstein J, Lenz HJ. PMID: 30852420; PMCID: PMC6436973.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    44. Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search. Hum Hered. 2018; 83(3):130-152. Kogan V, Millstein J, London SJ, Ober C, White SR, Naureckas ET, Gauderman WJ, Jackson DJ, Barraza-Villarreal A, Romieu I, Raby BA, Breton CV. PMID: 30669148; PMCID: PMC7365350.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    45. Gene Coexpression Networks in Whole Blood Implicate Multiple Interrelated Molecular Pathways in Obesity in People with Asthma. Obesity (Silver Spring). 2018 12; 26(12):1938-1948. Croteau-Chonka DC, Chen Z, Barnes KC, Barraza-Villarreal A, Celedón JC, Gauderman WJ, Gilliland FD, Krishnan JA, Liu AH, London SJ, Martinez FD, Millstein J, Naureckas ET, Nicolae DL, White SR, Ober C, Weiss ST, Raby BA. PMID: 30358166; PMCID: PMC6262830.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    46. Association between AXL promoter methylation and lung function growth during adolescence. Epigenetics. 2018; 13(10-11):1027-1038. Gao L, Urman R, Millstein J, Siegmund KD, Dubeau L, Breton CV. PMID: 30277126; PMCID: PMC6342069.
      View in: PubMed   Mentions:    Fields:    
    47. Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy. Clin Colorectal Cancer. 2019 03; 18(1):e8-e19. Tokunaga R, Cao S, Naseem M, Lo JH, Battaglin F, Puccini A, Berger MD, Soni S, Millstein J, Zhang W, Stintzing S, Loupakis F, Cremolini C, Heinemann V, Falcone A, Lenz HJ. PMID: 30293873; PMCID: PMC6416082.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    48. Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. Clin Epigenetics. 2018 07 20; 10(1):98. Gao L, Liu X, Millstein J, Siegmund KD, Dubeau L, Maguire RL, Jim Zhang J, Fuemmeler BF, Kollins SH, Hoyo C, Murphy SK, Breton CV. PMID: 30029617; PMCID: PMC6054742.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    49. Single-Cell Digital Lysates Generated by Phase-Switch Microfluidic Device Reveal Transcriptome Perturbation of Cell Cycle. ACS Nano. 2018 05 22; 12(5):4687-4694. Chen Y, Millstein J, Liu Y, Chen GY, Chen X, Stucky A, Qu C, Fan JB, Chang X, Soleimany A, Wang K, Zhong J, Liu J, Gilliland FD, Li Z, Zhang X, Zhong JF. PMID: 29589910; PMCID: PMC5997256.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    50. Role of local CpG DNA methylation in mediating the 17q21 asthma susceptibility gasdermin B (GSDMB)/ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) expression quantitative trait locus. J Allergy Clin Immunol. 2018 06; 141(6):2282-2286.e6. Kothari PH, Qiu W, Croteau-Chonka DC, Martinez FD, Liu AH, Lemanske RF, Ober C, Krishnan JA, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, White SR, Naureckas ET, Millstein J, Gauderman WJ, Gilliland FD, Carey VJ, Weiss ST, Raby BA, Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium. PMID: 29374573; PMCID: PMC5994185.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    51. Epigenetic regulation of AXL and risk of childhood asthma symptoms. Clin Epigenetics. 2017; 9:121. Gao L, Millstein J, Siegmund KD, Dubeau L, Maguire R, Gilliland FD, Murphy SK, Hoyo C, Breton CV. PMID: 29177020; PMCID: PMC5688797.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    52. Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control. Am J Respir Crit Care Med. 2017 01 15; 195(2):179-188. Croteau-Chonka DC, Qiu W, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Gilliland FD, Millstein J, Gauderman WJ, Ober C, Krishnan JA, White SR, Naureckas ET, Nicolae DL, Barnes KC, London SJ, Barraza-Villarreal A, Carey VJ, Weiss ST, Raby BA, Asthma BioRepository for Integrative Genomic Exploration (Asthma BRIDGE) Consortium. PMID: 27494826; PMCID: PMC5394783.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    53. Prenatal Air Pollution Exposures, DNA Methyl Transferase Genotypes, and Associations with Newborn LINE1 and Alu Methylation and Childhood Blood Pressure and Carotid Intima-Media Thickness in the Children's Health Study. Environ Health Perspect. 2016 12; 124(12):1905-1912. Breton CV, Yao J, Millstein J, Gao L, Siegmund KD, Mack W, Whitfield-Maxwell L, Lurmann F, Hodis H, Avol E, Gilliland FD. PMID: 27219456; PMCID: PMC5132634.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    54. cit: hypothesis testing software for mediation analysis in genomic applications. Bioinformatics. 2016 08 01; 32(15):2364-5. Millstein J, Chen GK, Breton CV. PMID: 27153715; PMCID: PMC4965632.
      View in: PubMed   Mentions: 23     Fields:    
    55. NPPB is a novel candidate biomarker expressed by cancer-associated fibroblasts in epithelial ovarian cancer. Int J Cancer. 2015 Mar 15; 136(6):1390-401. Lawrenson K, Grun B, Lee N, Mhawech-Fauceglia P, Kan J, Swenson S, Lin YG, Pejovic T, Millstein J, Gayther SA. PMID: 25047817; PMCID: PMC4289413.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    56. Alteration of select gene expression patterns in individuals infected with HIV-1. J Med Virol. 2014 Apr; 86(4):678-86. Serrao E, Wang CH, Frederick T, Lee CL, Anthony P, Arribas-Layton D, Baker K, Millstein J, Kovacs A, Neamati N. PMID: 24482297; PMCID: PMC6894924.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    57. Screening-testing approaches for gene-gene and gene-environment interactions using independent statistics. Front Genet. 2013; 4:306. Millstein J. PMID: 24416039; PMCID: PMC3874470.
      View in: PubMed   Mentions: 2  
    58. Computationally efficient permutation-based confidence interval estimation for tail-area FDR. Front Genet. 2013; 4:179. Millstein J, Volfson D. PMID: 24062767; PMCID: PMC3775454.
      View in: PubMed   Mentions: 14  
    59. Mapping the genetic architecture of gene expression in human liver. PLoS Biol. 2008 May 06; 6(5):e107. Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R. PMID: 18462017; PMCID: PMC2365981.
      View in: PubMed   Mentions: 611     Fields:    Translation:HumansAnimalsCells
    60. Health effects of the 2003 Southern California wildfires on children. Am J Respir Crit Care Med. 2006 Dec 01; 174(11):1221-8. Künzli N, Avol E, Wu J, Gauderman WJ, Rappaport E, Millstein J, Bennion J, McConnell R, Gilliland FD, Berhane K, Lurmann F, Winer A, Peters JM. PMID: 16946126; PMCID: PMC2648104.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansPHPublic Health
    61. Identifying susceptibility genes by using joint tests of association and linkage and accounting for epistasis. BMC Genet. 2005 Dec 30; 6 Suppl 1:S147. Millstein J, Siegmund KD, Conti DV, Gauderman WJ. PMID: 16451607; PMCID: PMC1866788.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    62. A testing framework for identifying susceptibility genes in the presence of epistasis. Am J Hum Genet. 2006 Jan; 78(1):15-27. Millstein J, Conti DV, Gilliland FD, Gauderman WJ. PMID: 16385446; PMCID: PMC1380213.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    63. Birth outcomes and prenatal exposure to ozone, carbon monoxide, and particulate matter: results from the Children's Health Study. Environ Health Perspect. 2005 Nov; 113(11):1638-44. Salam MT, Millstein J, Li YF, Lurmann FW, Margolis HG, Gilliland FD. PMID: 16263524; PMCID: PMC1310931.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansPHPublic Health
    64. Testing association and linkage using affected-sib-parent study designs. Genet Epidemiol. 2005 Nov; 29(3):225-33. Millstein J, Siegmund KD, Conti DV, Gauderman WJ. PMID: 16121357.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    65. Effects of ambient air pollutants on asthma medication use and wheezing among fourth-grade school children from 12 Southern California communities enrolled in The Children's Health Study. Arch Environ Health. 2004 Oct; 59(10):505-14. Millstein J, Gilliland F, Berhane K, Gauderman WJ, McConnell R, Avol E, Rappaport EB, Peters JM. PMID: 16425660.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    66. Comparison of age-length and growth-increment general growth models of the Schnute type in the Pacific Blue Mussel, Mytilus trossulus Gould. J Exp Mar Biol Ecol. 2001 Jul 30; 262(2):155-176. Millstein J, O'Clair CE. PMID: 11445085.
      View in: PubMed   Mentions:
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