Evanthia Roussos Torres, MD, PhD

Title(s)Assistant Professor of Medicine and Biochemistry & Molecular Medicine
SchoolKeck School of Medicine of Usc
AddressNOR 6412 NTT
Health Sciences Campus
Los Angeles CA 90089
ORCID ORCID Icon0000-0002-0740-5102 Additional info
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    Dr. Roussos Torres received a BS in Microbiology, Immunology and Molecular Genetics and a
    BA in World Arts and Cultures with a concentration in Dance from the University of California
    at Los Angeles (UCLA). She then went on to receive her combined MD/PhD from the Medical
    Scientist Training Program at the Albert Einstein College of Medicine in New York. She then
    completed her internal medicine residency at the Hospital of the University of Pennsylvania and
    her hematology/ oncology fellowship training at the University of Pennsylvania and Johns
    Hopkins University. Dr. Roussos Torres graduated from fellowship and began her faculty career
    as an Assistant Professor at Johns Hopkins University and is now an Assistant Professor at the
    University of Southern California where she leads her own lab and works collaboratively with
    other physicians and physician scientists to continue her work in immune-oncology with a
    specific interest in breast cancer and the tumor immune suppressive microenvironment.

    Dr. Roussos Torres is very passionate about her research as well as her care of patients with
    cancer and training of the fellows to become compassionate and knowledgeable physicians. She
    is driven to make memorable contributions to the field of cancer research given her personal
    experience advocating for her mother who died from metastatic breast cancer in 2016. Dr.
    Roussos Torres felt passionate about having an impact on the field of breast cancer prior to her
    mother’s diagnosis but learning about the devastation of metastatic disease as the family member
    of a patient provided a different perspective and drive for novel treatment options.

    Dr. Roussos Torres loves her work but also prioritizes her family life; her husband Dr. Stephen
    Torres is an orthopedic surgeon, specializing in sports medicine and together they have three
    sons, Owen, James and Luke who fill their life with joy and make every day a wonder! The
    Torres family also has a Chesapeake Bay retriever, Emma who greatly contributes to her active
    lifestyle! Dr. Roussos Torres enjoys traveling, eating out at new restaurants and road biking! Dr.
    Roussos Torres grew up in Santa Monica and is so happy to work close to where she grew up to
    raise her family near her siblings, their families, and her father who still resides here.

    Laboratory website: https://sites.usc.edu/roussostorreslab/

    Publications library: https://www-ncbi-nlm-nihgov.libproxy2.usc.edu/myncbi/1pwdQqmmnMeUHt/bibliography/public/

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Evaluating the impact of age on immune checkpoint therapy biomarkers. Cell Rep. 2021 08 24; 36(8):109599. Erbe R, Wang Z, Wu S, Xiu J, Zaidi N, La J, Tuck D, Fillmore N, Giraldo NA, Topper M, Baylin S, Lippman M, Isaacs C, Basho R, Serebriiskii I, Lenz HJ, Astsaturov I, Marshall J, Taverna J, Lee J, Jaffee EM, Roussos Torres ET, Weeraratna A, Easwaran H, Fertig EJ. PMID: 34433020; PMCID: PMC8757482.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    2. Phase I Study of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors (ETCTN-9844). Clin Cancer Res. 2021 11 01; 27(21):5828-5837. Roussos Torres ET, Rafie C, Wang C, Lim D, Brufsky A, LoRusso P, Eder JP, Chung V, Downs M, Geare M, Piekarz R, Streicher H, Anforth L, Rudek MA, Zhu Q, Besharati S, Cimino-Mathews A, Anders RA, Stearns V, Jaffee EM, Connolly RM. PMID: 34135021; PMCID: PMC8563383.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    3. Lymph Node Immune Profiles as Predictive Biomarkers for Immune Checkpoint Inhibitor Response. Front Mol Biosci. 2021; 8:674558. Goode EF, Roussos Torres ET, Irshad S. PMID: 34141724; PMCID: PMC8205515.
      View in: PubMed   Mentions: 11  
    4. Clocking cancer: the circadian clock as a target in cancer therapy. Oncogene. 2021 May; 40(18):3187-3200. Battaglin F, Chan P, Pan Y, Soni S, Qu M, Spiller ER, Castanon S, Roussos Torres ET, Mumenthaler SM, Kay SA, Lenz HJ. PMID: 33846572; PMCID: PMC8549632.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimals
    5. Phenotypic shifts of tumor associated macrophages and STAT3 mediated suppression of myeloid derived suppressor cells drive sensitization of HER2+ tumor immunity. bioRxiv. 2021. Sidiropoulos DN, Rafie C, Christmas BJ, Davis-Marcisak EF, Sharma G, Bigelow E, Gupta A, Yegnasubramanian S, Stearns V, Connolly RM, Gaykalova DA, Kagohara LT, Jaffee EM, Fertig EJ, Roussos Torres ET. View Publication.
    6. Adopting an alternative structure for clinical trials in immunotherapy. Expert Rev Anticancer Ther. 2021 04; 21(4):373-375. Roussos Torres ET, Epstein AL. PMID: 33435760.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    7. Management of Breast Cancer During the COVID-19 Pandemic: A Stage- and Subtype-Specific Approach. JCO Oncol Pract. 2020 Oct; 16(10):665-674. Sheng JY, Santa-Maria CA, Mangini N, Norman H, Couzi R, Nunes R, Wilkinson M, Visvanathan K, Connolly RM, Roussos Torres ET, Fetting JH, Armstrong DK, Tao JJ, Jacobs L, Wright JL, Thorner ED, Hodgdon C, Horn S, Wolff AC, Stearns V, Smith KL. PMID: 32603252; PMCID: PMC7564133.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCellsPHPublic Health
    8. Regulation of the tumor immune microenvironment and vascular normalization in TNBC murine models by a novel peptide. Oncoimmunology. 2020 05 14; 9(1):1760685. Mirando AC, Patil A, Rafie CI, Christmas BJ, Pandey NB, Stearns V, Jaffee EM, Roussos Torres ET, Popel AS. PMID: 32923118; PMCID: PMC7458646.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    9. Best Foot Forward: Neoadjuvant Systemic Therapy as Standard of Care in Triple-Negative and HER2-Positive Breast Cancer. Am Soc Clin Oncol Educ Book. 2020 Mar; 40:1-16. Sharma P, Connolly RM, Roussos Torres ET, Thompson A. PMID: 32315235.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    10. Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors. Front Bioeng Biotechnol. 2020; 8:141. Wang H, Sové RJ, Jafarnejad M, Rahmeh S, Jaffee EM, Stearns V, Roussos Torres ET, Connolly RM, Popel AS. PMID: 32158754; PMCID: PMC7051945.
      View in: PubMed   Mentions: 29  
    11. Differential Variation Analysis Enables Detection of Tumor Heterogeneity Using Single-Cell RNA-Sequencing Data. Cancer Res. 2019 10 01; 79(19):5102-5112. Davis-Marcisak EF, Sherman TD, Orugunta P, Stein-O'Brien GL, Puram SV, Roussos Torres ET, Hopkins AC, Jaffee EM, Favorov AV, Afsari B, Goff LA, Fertig EJ. PMID: 31337651; PMCID: PMC6844448.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    12. A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell-Mediated Anticancer Activity. Cancer Immunol Res. 2019 03; 7(3):428-442. Ma HS, Poudel B, Torres ER, Sidhom JW, Robinson TM, Christmas B, Scott B, Cruz K, Woolman S, Wall VZ, Armstrong T, Jaffee EM. PMID: 30642833; PMCID: PMC6397686.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    13. Optimizing HER2-Directed Therapy in Early-Stage Breast Cancer. Current Breast Cancer Reports. 2018. Roussos Torres ET, Connolly RM. View Publication.
    14. Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs. Cancer Immunol Res. 2018 12; 6(12):1561-1577. Christmas BJ, Rafie CI, Hopkins AC, Scott BA, Ma HS, Cruz KA, Woolman S, Armstrong TD, Connolly RM, Azad NA, Jaffee EM, Roussos Torres ET. PMID: 30341213; PMCID: PMC6279584.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    15. N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors. J Cell Sci. 2012 Feb 01; 125(Pt 3):724-34. Gligorijevic B, Wyckoff J, Yamaguchi H, Wang Y, Roussos ET, Condeelis J. PMID: 22389406; PMCID: PMC3367832.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    16. Setup and use of a two-laser multiphoton microscope for multichannel intravital fluorescence imaging. Nat Protoc. 2011 Sep 08; 6(10):1500-20. Entenberg D, Wyckoff J, Gligorijevic B, Roussos ET, Verkhusha VV, Pollard JW, Condeelis J. PMID: 21959234; PMCID: PMC4028841.
      View in: PubMed   Mentions: 79     Fields:    Translation:Animals
    17. Chemotaxis in cancer. Nat Rev Cancer. 2011 Jul 22; 11(8):573-87. Roussos ET, Condeelis JS, Patsialou A. PMID: 21779009; PMCID: PMC4030706.
      View in: PubMed   Mentions: 423     Fields:    Translation:HumansAnimalsCells
    18. Mena invasive (MenaINV) promotes multicellular streaming motility and transendothelial migration in a mouse model of breast cancer. J Cell Sci. 2011 Jul 01; 124(Pt 13):2120-31. Roussos ET, Balsamo M, Alford SK, Wyckoff JB, Gligorijevic B, Wang Y, Pozzuto M, Stobezki R, Goswami S, Segall JE, Lauffenburger DA, Bresnick AR, Gertler FB, Condeelis JS. PMID: 21670198; PMCID: PMC3113666.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    19. Mena invasive (Mena(INV)) and Mena11a isoforms play distinct roles in breast cancer cell cohesion and association with TMEM. Clin Exp Metastasis. 2011 Aug; 28(6):515-27. Roussos ET, Goswami S, Balsamo M, Wang Y, Stobezki R, Adler E, Robinson BD, Jones JG, Gertler FB, Condeelis JS, Oktay MH. PMID: 21484349; PMCID: PMC3459587.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    20. Mena deficiency delays tumor progression and decreases metastasis in polyoma middle-T transgenic mouse mammary tumors. Breast Cancer Res. 2010; 12(6):R101. Roussos ET, Wang Y, Wyckoff JB, Sellers RS, Wang W, Li J, Pollard JW, Gertler FB, Condeelis JS. PMID: 21108830; PMCID: PMC3046446.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    21. AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment. Cancer Res. 2010 Oct 01; 70(19):7360-4. Roussos ET, Keckesova Z, Haley JD, Epstein DM, Weinberg RA, Condeelis JS. PMID: 20823151.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimalsCells
    22. Differential enhancement of breast cancer cell motility and metastasis by helical and kinase domain mutations of class IA phosphoinositide 3-kinase. Cancer Res. 2009 Dec 01; 69(23):8868-76. Pang H, Flinn R, Patsialou A, Wyckoff J, Roussos ET, Wu H, Pozzuto M, Goswami S, Condeelis JS, Bresnick AR, Segall JE, Backer JM. PMID: 19903845; PMCID: PMC2793177.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    23. A Mena invasion isoform potentiates EGF-induced carcinoma cell invasion and metastasis. Dev Cell. 2008 Dec; 15(6):813-28. Philippar U, Roussos ET, Oser M, Yamaguchi H, Kim HD, Giampieri S, Wang Y, Goswami S, Wyckoff JB, Lauffenburger DA, Sahai E, Condeelis JS, Gertler FB. PMID: 19081071; PMCID: PMC2637261.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansAnimalsCells
    24. Genetic analysis of the diabetes-prone C57BLKS/J mouse strain reveals genetic contribution from multiple strains. Biochim Biophys Acta. 2006 Apr; 1762(4):440-6. Mao HZ, Roussos ET, Péterfy M. PMID: 16481151.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    25. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res. 2003 Mar; 9(3):1136-44. Ma MH, Yang HH, Parker K, Manyak S, Friedman JM, Altamirano C, Wu ZQ, Borad MJ, Frantzen M, Roussos E, Neeser J, Mikail A, Adams J, Sjak-Shie N, Vescio RA, Berenson JR. PMID: 12631619.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    26. Identification of polymorphisms of the IkappaBalpha gene associated with an increased risk of multiple myeloma. Cancer Genet Cytogenet. 2002 Aug; 137(1):43-8. Parker KM, Ma MH, Manyak S, Altamirano CV, Tang YM, Frantzen M, Mikail A, Roussos E, Sjak-Shie N, Vescio RA, Berenson JR. PMID: 12377412.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
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