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    Darcy Spicer, MD

    TitleAssociate Professor of Clinical Medicine
    SchoolKeck School of Medicine of USC
    DepartmentMedicine
    AddressNOR 3446
    Health Sciences Campus
    Los Angeles California 90089-9173
    Phone+1 323 865 3904
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      Other Positions
      TitleAssistant Dean For Clinical Research Studies

      TitleChief, Division of Oncology, Department of Medicine/Cancer Center

      TitleIrb Director & Co Director, Lynne Cohen Clinic


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      Dr. Spicer has been on faculty at the Keck School of Medicine at USC since 1980 when he began as a Clinical Instructor of Medicine in the Department of Oncology. Currently an associate professor, Dr. Spicer is also the Co-Director of the Clinical Investigations Support Office at USC Norris Comprehensive Cancer and Hospital. Dr. Spicer holds several United States patents for his medical inventions and chairs Keck’s Institutional Review Board, overseeing that faculty research is conducted ethically. He is a medical oncology attending physician at both the LAC+USC Medical Center and the USC Norris Comprehensive Cancer Center, a General Medicine Ward Attending Physician at LAC+USC Medical Center and is the founder of Balance Pharmaceuticals based in Los Angeles.


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      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Agarwal SK, Daniels A, Drosman SR, Udoff L, Foster WG, Pike MC, Spicer D, Daniels JR. Treatment of Endometriosis with the GnRHa Deslorelin and Add-Back Estradiol and Supplementary Testosterone. Biomed Res Int. 2015; 2015:934164. PMID: 26881208.
        View in: PubMed
      2. Wu AH, Spicer D, Garcia A, Tseng CC, Hovanessian-Larsen L, Sheth P, Martin SE, Hawes D, Russell C, MacDonald H, Tripathy D, Su MY, Ursin G, Pike MC. Double-Blind Randomized 12-Month Soy Intervention Had No Effects on Breast MRI Fibroglandular Tissue Density or Mammographic Density. Cancer Prev Res (Phila). 2015 Oct; 8(10):942-51. PMID: 26276750.
        View in: PubMed
      3. Yu SS, Spicer D, Hawes D, Tseng CC, Yang CS, Pike MC, Wu AH. Biological effects of green tea capsule supplementation in pre-surgery postmenopausal breast cancer patients. Front Oncol. 2013; 3:298. PMID: 24380073.
        View in: PubMed
      4. Wu AH, Spicer D, Pike MC. Soy isoflavones for breast cancer risk reduction--letter. Cancer Prev Res (Phila). 2012 Jul; 5(7):984-5. PMID: 22693167.
        View in: PubMed
      5. Hovanessian-Larsen L, Taylor D, Hawes D, Spicer D, Press MF, Wu AH, Pike MC, Pearce CL. Lowering oral contraceptive norethindrone dose increases estrogen and progesterone receptor levels with no reduction in proliferation of breast epithelium: a randomized trial. Contraception. 2012 Sep; 86(3):238-43. PMID: 22325110.
        View in: PubMed
      6. Wu AH, Spicer D, Stanczyk FZ, Tseng CC, Yang CS, Pike MC. Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women. Cancer Prev Res (Phila). 2012 Mar; 5(3):393-402. PMID: 22246619.
        View in: PubMed
      7. Chung K, Hovanessian-Larsen LJ, Hawes D, Taylor D, Downey S, Spicer D, Stanczyk FZ, Patel S, Anderson AR, Pike MC, Wu AH, Pearce CL. Breast epithelial cell proliferation is markedly increased with short-term high levels of endogenous estrogen secondary to controlled ovarian hyperstimulation. Breast Cancer Res Treat. 2012 Apr; 132(2):653-60. PMID: 22083231.
        View in: PubMed
      8. Lee E, McKean-Cowdin R, Ma H, Spicer D, Van Den Berg D, Bernstein L, Ursin G. Characteristics of Triple-Negative Breast Cancer in Patients With a BRCA1 Mutation: Results From a Population-Based Study of Young Women. J Clin Oncol. 2011 Nov 20; 29(33):4373-80. PMID: 22010008.
        View in: PubMed
      9. Lee E, Nichols P, Groshen S, Spicer D, Lee AS. GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy. Int J Cancer. 2011 Feb 1; 128(3):726-31. PMID: 20473863.
        View in: PubMed
      10. Adams S, Chakravarthy AB, Donach M, Spicer D, Lymberis S, Singh B, Bauer JA, Hochman T, Goldberg JD, Muggia F, Schneider RJ, Pietenpol JA, Formenti SC. Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival. Breast Cancer Res Treat. 2010 Dec; 124(3):723-32. PMID: 20878462.
        View in: PubMed
      11. Chew HK, Doroshow JH, Frankel P, Margolin KA, Somlo G, Lenz HJ, Gordon M, Zhang W, Yang D, Russell C, Spicer D, Synold T, Bayer R, Hantel A, Stiff PJ, Tetef ML, Gandara DR, Albain KS. Phase II studies of gemcitabine and cisplatin in heavily and minimally pretreated metastatic breast cancer. J Clin Oncol. 2009 May 1; 27(13):2163-9. PMID: 19307510.
        View in: PubMed
      12. Taylor D, Pearce CL, Hovanessian-Larsen L, Downey S, Spicer D, Bartow S, Pike MC, Wu AH, Hawes D. Progesterone and estrogen receptors in pregnant and premenopausal non-pregnant normal human breast. Breast Cancer Res Treat. 2009 Nov; 118(1):161-8. PMID: 19205874.
        View in: PubMed
      13. Wu AH, Pike MC, Williams LD, Spicer D, Tseng CC, Churchwell MI, Doerge DR. Tamoxifen, soy, and lifestyle factors in Asian American women with breast cancer. J Clin Oncol. 2007 Jul 20; 25(21):3024-30. PMID: 17536081.
        View in: PubMed
      14. Weitzel JN, Buys SS, Sherman WH, Daniels A, Ursin G, Daniels JR, MacDonald DJ, Blazer KR, Pike MC, Spicer D. Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriers. Clin Cancer Res. 2007 Jan 15; 13(2 Pt 1):654-8. PMID: 17255289.
        View in: PubMed
      15. Lee E, Nichols P, Spicer D, Groshen S, Yu MC, Lee AS. GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer. Cancer Res. 2006 Aug 15; 66(16):7849-53. PMID: 16912156.
        View in: PubMed
      16. ten Tije AJ, Synold TW, Spicer D, Verweij J, Doroshow JH, Sparreboom A. Effect of valspodar on the pharmacokinetics of unbound paclitaxel. Invest New Drugs. 2003 Aug; 21(3):291-8. PMID: 14578679.
        View in: PubMed
      17. Formenti SC, Volm M, Skinner KA, Spicer D, Cohen D, Perez E, Bettini AC, Groshen S, Gee C, Florentine B, Press M, Danenberg P, Muggia F. Preoperative twice-weekly paclitaxel with concurrent radiation therapy followed by surgery and postoperative doxorubicin-based chemotherapy in locally advanced breast cancer: a phase I/II trial. J Clin Oncol. 2003 Mar 1; 21(5):864-70. PMID: 12610186.
        View in: PubMed
      18. Formenti SC, Spicer D, Skinner K, Cohen D, Groshen S, Bettini A, Naritoku W, Press M, Salonga D, Tsao-Wei D, Danenberg K, Danenberg P. Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer. Int J Radiat Oncol Biol Phys. 2002 Feb 1; 52(2):397-405. PMID: 11872285.
        View in: PubMed
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