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Donna Shoupe, MD

TitleProfessor of Obstetrics & Gynecology
InstitutionUniversity of Southern California
DepartmentObstetrics & Gynecology
AddressIRD 534 2020 Zonal Ave
Off Campus
Los Angeles CA 90033
Phone+1 323 226 3351
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Matsuo K, Machida H, Shoupe D, Melamed A, Muderspach LI, Roman LD, Wright JD. Ovarian Conservation and Overall Survival in Young Women With Early-Stage Cervical Cancer. Obstet Gynecol. 2017 01; 129(1):139-151. PMID: 27926642.
      View in: PubMed
    2. Matsuo K, Machida H, Shoupe D, Melamed A, Muderspach LI, Roman LD, Wright JD. Ovarian Conservation and Overall Survival in Young Women With Early-Stage Low-Grade Endometrial Cancer. Obstet Gynecol. 2016 10; 128(4):761-70. PMID: 27607873.
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    3. Nagelberg J, Burks H, Mucowski S, Shoupe D. The effect of home exercise on ovulation induction using clomiphene citrate in overweight underserved women with polycystic ovarian syndrome. Contracept Reprod Med. 2016; 1:14. PMID: 29201403.
      View in: PubMed
    4. Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis. Neurology. 2016 Aug 16; 87(7):699-708. PMID: 27421538; PMCID: PMC4999165 [Available on 08/16/17].
    5. Sherman ME, Drapkin RI, Horowitz NS, Crum CP, Friedman S, Kwon JS, Levine DA, Shih IeM, Shoupe D, Swisher EM, Walker J, Trabert B, Greene MH, Samimi G, Temkin SM, Minasian LM. Rationale for Developing a Specimen Bank to Study the Pathogenesis of High-Grade Serous Carcinoma: A Review of the Evidence. Cancer Prev Res (Phila). 2016 Sep; 9(9):713-20. PMID: 27221539.
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    6. Matsuo K, Gualtieri MR, Cahoon SS, Toboni MD, Machida H, Moeini A, Hasegawa K, Shoupe D, Roman LD. Contributing factors for menopausal symptoms after surgical staging for endometrial cancer. Menopause. 2016 05; 23(5):535-43. PMID: 26757269.
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    7. Hodis HN, Mack WJ, Henderson VW, Shoupe D, Budoff MJ, Hwang-Levine J, Li Y, Feng M, Dustin L, Kono N, Stanczyk FZ, Selzer RH, Azen SP. Vascular Effects of Early versus Late Postmenopausal Treatment with Estradiol. N Engl J Med. 2016 Mar 31; 374(13):1221-31. PMID: 27028912; PMCID: PMC4921205 [Available on 09/30/16].
    8. Shoupe D. LARC methods: entering a new age of contraception and reproductive health. Contracept Reprod Med. 2016; 1:4. PMID: 29201394.
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    9. Matsuo K, Gualtieri MR, Cahoon SS, Jung CE, Paulson RJ, Shoupe D, Muderspach LI, Wakatsuki A, Wright JD, Roman LD. Surgical menopause and increased risk of nonalcoholic fatty liver disease in endometrial cancer. Menopause. 2016 Feb; 23(2):189-96. PMID: 26173075.
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    10. Rodriguez M, Shoupe D. Surgical Menopause. Endocrinol Metab Clin North Am. 2015 Sep; 44(3):531-42. PMID: 26316241.
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    11. Hodis HN, Mack WJ, Shoupe D, Azen SP, Stanczyk FZ, Hwang-Levine J, Budoff MJ, Henderson VW. Methods and baseline cardiovascular data from the Early versus Late Intervention Trial with Estradiol testing the menopausal hormone timing hypothesis. Menopause. 2015 Apr; 22(4):391-401. PMID: 25380275; PMCID: PMC4376597.
    12. Shoupe D. Hormone replacement therapy: consensus and controversies. Panminerva Med. 2014; 56(4):263-72. PMID: 25288326.
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    13. Mucowski SJ, Mack WJ, Shoupe D, Kono N, Paulson R, Hodis HN. Effect of prior oophorectomy on changes in bone mineral density and carotid artery intima-media thickness in postmenopausal women. Fertil Steril. 2014 Apr; 101(4):1117-22. PMID: 24530156; PMCID: PMC4215065.
    14. Shoupe D. Individualizing hormone-therapy according to cardiovascular risk. Minerva Ginecol. 2013 Dec; 65(6):631-9. PMID: 24346251.
      View in: PubMed
    15. Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Karim R, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5. PMID: 24277815; PMCID: PMC3864289.
    16. Parker WH, Feskanich D, Broder MS, Chang E, Shoupe D, Farquhar CM, Berek JS, Manson JE. In reply. Obstet Gynecol. 2013 Aug; 122(2 Pt 1):396. PMID: 23969818.
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    17. Quaas AM, Kono N, Mack WJ, Hodis HN, Felix JC, Paulson RJ, Shoupe D. Effect of isoflavone soy protein supplementation on endometrial thickness, hyperplasia, and endometrial cancer risk in postmenopausal women: a randomized controlled trial. Menopause. 2013 Aug; 20(8):840-4. PMID: 23422867; PMCID: PMC3934100.
    18. Parker WH, Feskanich D, Broder MS, Chang E, Shoupe D, Farquhar CM, Berek JS, Manson JE. Long-term mortality associated with oophorectomy compared with ovarian conservation in the nurses' health study. Obstet Gynecol. 2013 Apr; 121(4):709-16. PMID: 23635669; PMCID: PMC4254662.
    19. Shoupe D. Individualizing hormone-therapy according to cardiovascular risk. Minerva Med. 2012 Oct; 103(5):343-52. PMID: 23042369.
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    20. Hodis HN, Mack WJ, Kono N, Azen SP, Shoupe D, Hwang-Levine J, Petitti D, Whitfield-Maxwell L, Yan M, Franke AA, Selzer RH. Isoflavone soy protein supplementation and atherosclerosis progression in healthy postmenopausal women: a randomized controlled trial. Stroke. 2011 Nov; 42(11):3168-75. PMID: 21903957; PMCID: PMC3202054.
    21. Shoupe D. Individualizing hormone therapy to minimize risk: accurate assessment of risks and benefits. Womens Health (Lond). 2011 Jul; 7(4):475-85. PMID: 21790340.
      View in: PubMed
    22. Parker WH, Jacoby V, Shoupe D, Rocca W. Effect of bilateral oophorectomy on women's long-term health. Womens Health (Lond). 2009 Sep; 5(5):565-76. PMID: 19702455.
      View in: PubMed
    23. Parker WH, Broder MS, Chang E, Feskanich D, Farquhar C, Liu Z, Shoupe D, Berek JS, Hankinson S, Manson JE. Ovarian conservation at the time of hysterectomy and long-term health outcomes in the nurses' health study. Obstet Gynecol. 2009 May; 113(5):1027-37. PMID: 19384117; PMCID: PMC3791619.
    24. Parker WH, Shoupe D, Broder MS, Liu Z, Farquhar C, Berek JS. Elective oophorectomy in the gynecological patient: when is it desirable? Curr Opin Obstet Gynecol. 2007 Aug; 19(4):350-4. PMID: 17625417.
      View in: PubMed
    25. Parker WH, Broder MS, Liu Z, Shoupe D, Farquhar C, Berek JS. Ovarian conservation at the time of hysterectomy for benign disease. Clin Obstet Gynecol. 2007 Jun; 50(2):354-61. PMID: 17513923.
      View in: PubMed
    26. Shoupe D, Parker WH, Broder MS, Liu Z, Farquhar C, Berek JS. Elective oophorectomy for benign gynecological disorders. Menopause. 2007 May-Jun; 14(3 Pt 2):580-5. PMID: 17476148.
      View in: PubMed
    27. Steiner AZ, Xiang M, Mack WJ, Shoupe D, Felix JC, Lobo RA, Hodis HN. Unopposed estradiol therapy in postmenopausal women: results from two randomized trials. Obstet Gynecol. 2007 Mar; 109(3):581-7. PMID: 17329508.
      View in: PubMed
    28. Steiner AZ, Hodis HN, Lobo RA, Shoupe D, Xiang M, Mack WJ. Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial. Menopause. 2005 Nov-Dec; 12(6):728-33. PMID: 16278616.
      View in: PubMed
    29. Parker WH, Broder MS, Liu Z, Shoupe D, Farquhar C, Berek JS. Ovarian conservation at the time of hysterectomy for benign disease. Obstet Gynecol. 2005 Aug; 106(2):219-26. PMID: 16055568.
      View in: PubMed
    30. Gass MS, Rebar RW, Cuffie-Jackson C, Cedars MI, Lobo RA, Shoupe D, Judd HL, Buyalos RP, Clisham PR. A short study in the treatment of hot flashes with buccal administration of 17-beta estradiol. Maturitas. 2004 Oct 15; 49(2):140-7. PMID: 15474758.
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    31. Mack WJ, Slater CC, Xiang M, Shoupe D, Lobo RA, Hodis HN. Elevated subclinical atherosclerosis associated with oophorectomy is related to time since menopause rather than type of menopause. Fertil Steril. 2004 Aug; 82(2):391-7. PMID: 15302289.
      View in: PubMed
    32. Hodis HN, Mack WJ, Azen SP, Lobo RA, Shoupe D, Mahrer PR, Faxon DP, Cashin-Hemphill L, Sanmarco ME, French WJ, Shook TL, Gaarder TD, Mehra AO, Rabbani R, Sevanian A, Shil AB, Torres M, Vogelbach KH, Selzer RH. Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women. N Engl J Med. 2003 Aug 07; 349(6):535-45. PMID: 12904518.
      View in: PubMed
    33. Hodis HN, Mack WJ, Lobo RA, Shoupe D, Sevanian A, Mahrer PR, Selzer RH, Liu Cr CR, Liu Ch CH, Azen SP. Estrogen in the prevention of atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2001 Dec 04; 135(11):939-53. PMID: 11730394.
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    34. Slater CC, Zhang C, Hodis HN, Mack WJ, Boostanfar R, Shoupe D, Paulson RJ, Stanczyk FZ. Comparison of estrogen and androgen levels after oral estrogen replacement therapy. J Reprod Med. 2001 Dec; 46(12):1052-6. PMID: 11789085.
      View in: PubMed
    35. Utian WH, Shoupe D, Bachmann G, Pinkerton JV, Pickar JH. Relief of vasomotor symptoms and vaginal atrophy with lower doses of conjugated equine estrogens and medroxyprogesterone acetate. Fertil Steril. 2001 Jun; 75(6):1065-79. PMID: 11384629.
      View in: PubMed
    36. Slater CC, Hodis HN, Mack WJ, Shoupe D, Paulson RJ, Stanczyk FZ. Markedly elevated levels of estrone sulfate after long-term oral, but not transdermal, administration of estradiol in postmenopausal women. Menopause. 2001 May-Jun; 8(3):200-3. PMID: 11355042.
      View in: PubMed
    37. Shoupe D. HRT dosing regimens: continuous versus cyclic-pros and cons. Int J Fertil Womens Med. 2001 Jan-Feb; 46(1):7-15. PMID: 11294619.
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    38. Shoupe D. Hysterectomy or an alternative? Hosp Pract (1995). 2000 Sep 15; 35(9):55-62; quiz 92. PMID: 11004927.
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    39. Henderson VW, Paganini-Hill A, Miller BL, Elble RJ, Reyes PF, Shoupe D, McCleary CA, Klein RA, Hake AM, Farlow MR. Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo-controlled trial. Neurology. 2000 Jan 25; 54(2):295-301. PMID: 10668686.
      View in: PubMed
    40. Shoupe D. Hormone replacement therapy: reassessing the risks and benefits. Hosp Pract (1995). 1999 Aug 15; 34(8):97-103, 107-8, 113-4. PMID: 10459365.
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    41. Shoupe D. Androgens and bone: clinical implications for menopausal women. Am J Obstet Gynecol. 1999 Mar; 180(3 Pt 2):S329-33. PMID: 10076175.
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    42. Shoupe D. Contraception in the 1990s. Curr Opin Obstet Gynecol. 1996 Jun; 8(3):211-5. PMID: 8818532.
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    43. Rapkin AJ, Shoupe D, Reading A, Daneshgar KK, Goldman L, Bohn Y, Brann DW, Mahesh VB. Decreased central opioid activity in premenstrual syndrome: luteinizing hormone response to naloxone. J Soc Gynecol Investig. 1996 Mar-Apr; 3(2):93-8. PMID: 8796815.
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    44. Ballagh SA, Mishell DR, Lacarra M, Shoupe D, Jackanicz TM, Eggena P. A contraceptive vaginal ring releasing norethindrone acetate and ethinyl estradiol. Contraception. 1994 Dec; 50(6):517-33. PMID: 7705095.
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    45. Mezrow G, Shoupe D, Spicer D, Lobo R, Leung B, Pike M. Depot leuprolide acetate with estrogen and progestin add-back for long-term treatment of premenstrual syndrome. Fertil Steril. 1994 Nov; 62(5):932-7. PMID: 7926137.
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    46. Shoupe D. New progestins--clinical experiences: gestodene. Am J Obstet Gynecol. 1994 May; 170(5 Pt 2):1562-8. PMID: 8178907.
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    47. Shoupe D. Multicenter randomized comparative trial of two low-dose triphasic combined oral contraceptives containing desogestrel or norethindrone. Obstet Gynecol. 1994 May; 83(5 Pt 1):679-85. PMID: 8164925.
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    48. Spicer DV, Ursin G, Parisky YR, Pearce JG, Shoupe D, Pike A, Pike MC. Changes in mammographic densities induced by a hormonal contraceptive designed to reduce breast cancer risk. J Natl Cancer Inst. 1994 Mar 16; 86(6):431-6. PMID: 8120917.
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    49. Bopp B, Shoupe D. Luteal phase defects. J Reprod Med. 1993 May; 38(5):348-56. PMID: 8320670.
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    50. Shoupe D. Effects of desogestrel on carbohydrate metabolism. Am J Obstet Gynecol. 1993 Mar; 168(3 Pt 2):1041-7. PMID: 8447358.
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    51. Shoupe D, Meme D, Mezrow G, Lobo RA. Prevention of endometrial hyperplasia in postmenopausal women with intrauterine progesterone. N Engl J Med. 1991 Dec 19; 325(25):1811-2. PMID: 1944490.
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    52. Mishell DR, Shoupe D, Moyer DL, Roy S, Page MA. Postmenopausal hormone replacement with a combination estrogen-progestin regimen for five days per week. J Reprod Med. 1991 May; 36(5):351-5. PMID: 2061882.
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    53. Shoupe D, Horenstein J, Mishell DR, Lacarra M, Medearis A. Characteristics of ovarian follicular development in Norplant users. Fertil Steril. 1991 Apr; 55(4):766-70. PMID: 1901281.
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    54. Shoupe D, Mishell DR, Bopp BL, Fielding M. The significance of bleeding patterns in Norplant implant users. Obstet Gynecol. 1991 Feb; 77(2):256-60. PMID: 1899135.
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    55. Kjos SL, Shoupe D, Douyan S, Friedman RL, Bernstein GS, Mestman JH, Mishell DR. Effect of low-dose oral contraceptives on carbohydrate and lipid metabolism in women with recent gestational diabetes: results of a controlled, randomized, prospective study. Am J Obstet Gynecol. 1990 Dec; 163(6 Pt 1):1822-7. PMID: 2256489.
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    56. Shoupe D, Mishell DR, Fossum G, Bopp BL, Spitz IM, Lobo RA. Antiprogestin treatment decreases midluteal luteinizing hormone pulse amplitude and primarily exerts a pituitary inhibition. Am J Obstet Gynecol. 1990 Dec; 163(6 Pt 1):1982-5. PMID: 2256511.
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    57. Grimes DA, Bernstein L, Lacarra M, Shoupe D, Mishell DR. Predictors of failed attempted abortion with the antiprogestin mifepristone (RU 486). Am J Obstet Gynecol. 1990 Apr; 162(4):910-5; discussion 915-7. PMID: 2183618.
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    58. Shoupe D, Mishell DR. Norplant: subdermal implant system for long-term contraception. Am J Obstet Gynecol. 1989 May; 160(5 Pt 2):1286-92. PMID: 2497646.
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    59. Shoupe D, Mishell DR, Lacarra M, Lobo RA, Horenstein J, d'Ablaing G, Moyer D. Correlation of endometrial maturation with four methods of estimating day of ovulation. Obstet Gynecol. 1989 Jan; 73(1):88-92. PMID: 2642330.
      View in: PubMed
    60. Stanczyk FZ, Shoupe D, Nunez V, Macias-Gonzales P, Vijod MA, Lobo RA. A randomized comparison of nonoral estradiol delivery in postmenopausal women. Am J Obstet Gynecol. 1988 Dec; 159(6):1540-6. PMID: 3144919.
      View in: PubMed
    61. Grimes DA, Mishell DR, Shoupe D, Lacarra M. Early abortion with a single dose of the antiprogestin RU-486. Am J Obstet Gynecol. 1988 Jun; 158(6 Pt 1):1307-12. PMID: 2454578.
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    62. Shoupe D, Kjos S. Effects of oral contraceptives on the borderline NIDD patient. Int J Fertil. 1988; 33 Suppl:27-34. PMID: 2908038.
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    63. Shoupe D, Mishell DR, Lahteenmaki P, Heikinheimo O, Birgerson L, Madkour H, Spitz IM. Effects of the antiprogesterone RU 486 in normal women. I. Single-dose administration in the midluteal phase. Am J Obstet Gynecol. 1987 Dec; 157(6):1415-20. PMID: 2827481.
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    64. Shoupe D, Mishell DR, Page MA, Madkour H, Spitz IM, Lobo RA. Effects of the antiprogesterone RU 486 in normal women. II. Administration in the late follicular phase. Am J Obstet Gynecol. 1987 Dec; 157(6):1421-6. PMID: 2827482.
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    65. Chiang RS, Barnes RB, Shoupe D, Lobo RA. Dose-related changes in LH bioactivity with intranasal GnRH agonist administration. Contraception. 1985 Oct; 32(4):347-57. PMID: 2934222.
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    66. Lobo RA, Roy S, Shoupe D, Endres DB, Adams JS, Rude RK, Singer FR. Estrogen and progestin effects on urinary calcium and calciotropic hormones in surgically-induced postmenopausal women. Horm Metab Res. 1985 Jul; 17(7):370-3. PMID: 3161813.
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    67. Shoupe D, Lobo RA. Prolactin response after gonadotropin-releasing hormone in the polycystic ovary syndrome. Fertil Steril. 1985 Apr; 43(4):549-53. PMID: 3921411.
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    68. Lobo RA, Shoupe D, Serafini P, Brinton D, Horton R. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women. Fertil Steril. 1985 Feb; 43(2):200-5. PMID: 3967781.
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    69. Shoupe D, Montz FJ, Lobo RA. The effects of estrogen and progestin on endogenous opioid activity in oophorectomized women. J Clin Endocrinol Metab. 1985 Jan; 60(1):178-83. PMID: 2981084.
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    70. Shoupe D, Lobo RA. Evidence for altered catecholamine metabolism in polycystic ovary syndrome. Am J Obstet Gynecol. 1984 Nov 01; 150(5 Pt 1):566-71. PMID: 6437227.
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    71. Lobo RA, Shoupe D, Roy S, Paul W. Central and peripheral metabolites of norepinephrine and dopamine in postmenopausal women. Am J Obstet Gynecol. 1984 Jul 01; 149(5):548-52. PMID: 6742025.
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    72. Chang SP, Shoupe D, Kletzky OA, Lobo RA. Differences in the ratio of bioactive to immunoreactive serum luteinizing hormone during vasomotor flushes and hormonal therapy in postmenopausal women. J Clin Endocrinol Metab. 1984 May; 58(5):925-9. PMID: 6323519.
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    73. Shoupe D, Lobo RA. The influence of androgens on insulin resistance. Fertil Steril. 1984 Mar; 41(3):385-8. PMID: 6230259.
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    74. Lobo RA, Shoupe D, Chang SP, Campeau J. The control of bioactive luteinizing hormone secretion in women with polycystic ovary syndrome. Am J Obstet Gynecol. 1984 Feb 15; 148(4):423-8. PMID: 6364811.
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    75. Shoupe D, Kumar DD, Lobo RA. Insulin resistance in polycystic ovary syndrome. Am J Obstet Gynecol. 1983 Nov 01; 147(5):588-92. PMID: 6227251.
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