Julie Culver

Title(s)Instructor of Clinical Medicine
SchoolKeck School of Medicine of Usc
AddressUSC Norris Comprehensive Cancer Center
Health Sciences Campus
Los Angeles CA 90089
Phone+1 323 865 0911
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    Julie Culver, MS, LCGC, CCRP is the Director of Genetic Counseling at the USC Norris Cancer Hospital and is a Clinical Instructor of Medicine in the USC Keck School of Medicine. She provides cancer genetic counseling for individuals and family at risk of having inherited cancer syndromes.
    Her research pertains to genetic testing for hereditary cancer, medical decision-making following genetic testing, implementation of genetic testing, and participant engagement in genomics research. She has taught breast cancer risk assessment to health professionals and students since 2004.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Transcriptome analysis provides critical answers to the "variants of uncertain significance" conundrum. Hum Mutat. 2022 May 05. Postel M, Culver JO, Ricker C, Craig DW. PMID: 35510381.
      View in: PubMed   Mentions:
    2. Psychosocial outcomes following germline multigene panel testing in an ethnically and economically diverse cohort of patients. Cancer. 2021 04 15; 127(8):1275-1285. Culver JO, Ricker CN, Bonner J, Kidd J, Sturgeon D, Hodan R, Kingham K, Lowstuter K, Chun NM, Lebensohn AP, Rowe-Teeter C, Levonian P, Partynski K, Lara-Otero K, Hong C, Morales Pichardo J, Mills MA, Brown K, Lerman C, Ladabaum U, McDonnell KJ, Ford JM, Gruber SB, Kurian AW, Idos GE. PMID: 33320347; PMCID: PMC8058169.
      View in: PubMed   Mentions: 1     Fields:    
    3. Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D. J Natl Cancer Inst. 2020 12 14; 112(12):1242-1250. Yang X, Song H, Leslie G, Engel C, Hahnen E, Auber B, Horváth J, Kast K, Niederacher D, Turnbull C, Houlston R, Hanson H, Loveday C, Dolinsky JS, LaDuca H, Ramus SJ, Menon U, Rosenthal AN, Jacobs I, Gayther SA, Dicks E, Nevanlinna H, Aittomäki K, Pelttari LM, Ehrencrona H, Borg Å, Kvist A, Rivera B, Hansen TVO, Djursby M, Lee A, Dennis J, Bowtell DD, Traficante N, Diez O, Balmaña J, Gruber SB, Chenevix-Trench G, Investigators K, Jensen A, Kjær SK, Høgdall E, Castéra L, Garber J, Janavicius R, Osorio A, Golmard L, Vega A, Couch FJ, Robson M, Gronwald J, Domchek SM, Culver JO, de la Hoya M, Easton DF, Foulkes WD, Tischkowitz M, Meindl A, Schmutzler RK, Pharoah PDP, Antoniou AC. PMID: 32107557; PMCID: PMC7735771.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    4. Inhibition of poly(ADP-ribose) polymerase induces synthetic lethality in BRIP1 deficient ovarian epithelial cells. Gynecol Oncol. 2020 12; 159(3):869-876. Ciccone MA, Adams CL, Bowen C, Thakur T, Ricker C, Culver JO, Maoz A, Melas M, Idos GE, Jeyasekharan AD, Matsuo K, Roman LD, Gruber SB, McDonnell KJ. PMID: 33032822.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families. J Clin Oncol. 2020 03 01; 38(7):674-685. Yang X, Leslie G, Doroszuk A, Schneider S, Allen J, Decker B, Dunning AM, Redman J, Scarth J, Plaskocinska I, Luccarini C, Shah M, Pooley K, Dorling L, Lee A, Adank MA, Adlard J, Aittomäki K, Andrulis IL, Ang P, Barwell J, Bernstein JL, Bobolis K, Borg Å, Blomqvist C, Claes KBM, Concannon P, Cuggia A, Culver JO, Damiola F, de Pauw A, Diez O, Dolinsky JS, Domchek SM, Engel C, Evans DG, Fostira F, Garber J, Golmard L, Goode EL, Gruber SB, Hahnen E, Hake C, Heikkinen T, Hurley JE, Janavicius R, Kleibl Z, Kleiblova P, Konstantopoulou I, Kvist A, Laduca H, Lee ASG, Lesueur F, Maher ER, Mannermaa A, Manoukian S, McFarland R, McKinnon W, Meindl A, Metcalfe K, Mohd Taib NA, Moilanen J, Nathanson KL, Neuhausen S, Ng PS, Nguyen-Dumont T, Nielsen SM, Obermair F, Offit K, Olopade OI, Ottini L, Penkert J, Pylkäs K, Radice P, Ramus SJ, Rudaitis V, Side L, Silva-Smith R, Silvestri V, Skytte AB, Slavin T, Soukupova J, Tondini C, Trainer AH, Unzeitig G, Usha L, van Overeem Hansen T, Whitworth J, Wood M, Yip CH, Yoon SY, Yussuf A, Zogopoulos G, Goldgar D, Hopper JL, Chenevix-Trench G, Pharoah P, George SHL, Balmaña J, Houdayer C, James P, El-Haffaf Z, Ehrencrona H, Janatova M, Peterlongo P, Nevanlinna H, Schmutzler R, Teo SH, Robson M, Pal T, Couch F, Weitzel JN, Elliott A, Southey M, Winqvist R, Easton DF, Foulkes WD, Antoniou AC, Tischkowitz M. PMID: 31841383; PMCID: PMC7049229.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    6. Multicenter Prospective Cohort Study of the Diagnostic Yield and Patient Experience of Multiplex Gene Panel Testing For Hereditary Cancer Risk. JCO Precis Oncol. 2019 Mar; 3. Idos GE, Kurian AW, Ricker C, Sturgeon D, Culver JO, Kingham KE, Koff R, Chun NM, Rowe-Teeter C, Lebensohn AP, Levonian P, Lowstuter K, Partynski K, Hong C, Mills MA, Petrovchich I, Ma CS, Hartman AR, Allen B, Wenstrup RJ, Lancaster JM, Brown K, Kidd J, Evans B, Mukherjee B, McDonnell KJ, Ladabaum U, Ford JM, Gruber SB. PMID: 34322651; PMCID: PMC8260917.
      View in: PubMed   Mentions:
    7. Clinical testing of BRCA1 and BRCA2: a worldwide snapshot of technological practices. NPJ Genom Med. 2018; 3:7. Toland AE, Forman A, Couch FJ, Culver JO, Eccles DM, Foulkes WD, Hogervorst FBL, Houdayer C, Levy-Lahad E, Monteiro AN, Neuhausen SL, Plon SE, Sharan SK, Spurdle AB, Szabo C, Brody LC, BIC Steering Committee. PMID: 29479477; PMCID: PMC5814433.
      View in: PubMed   Mentions: 9  
    8. Patient communication of cancer genetic test results in a diverse population. Transl Behav Med. 2018 01 29; 8(1):85-94. Ricker CN, Koff RB, Qu C, Culver J, Sturgeon D, Kingham KE, Lowstuter K, Chun NM, Rowe-Teeter C, Lebensohn A, Levonian P, Partynski K, Lara-Otero K, Hong C, Petrovchich IM, Mills MA, Hartman AR, Allen B, Ladabaum U, McDonnell K, Ford JM, Gruber SB, Kurian AW, Idos GE. PMID: 29385580; PMCID: PMC6065549.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    9. Unexpected CDH1 Mutations Identified on Multigene Panels Pose Clinical Management Challenges. JCO Precis Oncol. 2017 Nov; 1:1-12. Lowstuter K, Espenschied CR, Sturgeon D, Ricker C, Karam R, LaDuca H, Culver JO, Dolinsky JS, Chao E, Sturgeon J, Speare V, Ma Y, Kingham K, Melas M, Idos GE, McDonnell KJ, Gruber SB. PMID: 35172483.
      View in: PubMed   Mentions:
    10. Increased yield of actionable mutations using multi-gene panels to assess hereditary cancer susceptibility in an ethnically diverse clinical cohort. Cancer Genet. 2016 Apr; 209(4):130-7. Ricker C, Culver JO, Lowstuter K, Sturgeon D, Sturgeon JD, Chanock CR, Gauderman WJ, McDonnell KJ, Idos GE, Gruber SB. PMID: 26908360; PMCID: PMC4835267.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    11. A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer. Cancer Genet. 2016 Mar; 209(3):75-81. McDonnell KJ, Gallanis GT, Heller KA, Melas M, Idos GE, Culver JO, Martin SE, Peng DH, Gruber SB. PMID: 26774355; PMCID: PMC6447287.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    12. Variants of uncertain significance in BRCA testing: evaluation of surgical decisions, risk perception, and cancer distress. Clin Genet. 2013 Nov; 84(5):464-72. Culver JO, Brinkerhoff CD, Clague J, Yang K, Singh KE, Sand SR, Weitzel JN. PMID: 23323793; PMCID: PMC3751990.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    13. Tumor protein p53 (TP53) testing and Li-Fraumeni syndrome : current status of clinical applications and future directions. Mol Diagn Ther. 2013 Feb; 17(1):31-47. Sorrell AD, Espenschied CR, Culver JO, Weitzel JN. PMID: 23355100; PMCID: PMC3627545.
      View in: PubMed   Mentions:
    14. Closing the loop: action research in a multimodal hereditary cancer patient conference is an effective tool to assess and address patient needs. J Cancer Educ. 2012 Jun; 27(3):467-77. Espenschied CR, MacDonald DJ, Culver JO, Sand S, Hurley K, Banks KC, Weitzel JN, Blazer KR. PMID: 22610836; PMCID: PMC3540105.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Essential elements of genetic cancer risk assessment, counseling, and testing: updated recommendations of the National Society of Genetic Counselors. J Genet Couns. 2012 Apr; 21(2):151-61. Riley BD, Culver JO, Skrzynia C, Senter LA, Peters JA, Costalas JW, Callif-Daley F, Grumet SC, Hunt KS, Nagy RS, McKinnon WC, Petrucelli NM, Bennett RL, Trepanier AM. PMID: 22134580.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    16. Personalized cancer genetics training for personalized medicine: improving community-based healthcare through a genetically literate workforce. Genet Med. 2011 Sep; 13(9):832-40. Blazer KR, Macdonald DJ, Culver JO, Huizenga CR, Morgan RJ, Uman GC, Weitzel JN. PMID: 21629123; PMCID: PMC3337331.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    17. Genetics, genomics, and cancer risk assessment: State of the Art and Future Directions in the Era of Personalized Medicine. CA Cancer J Clin. 2011 Sep-Oct; 61(5):327-59. Weitzel JN, Blazer KR, MacDonald DJ, Culver JO, Offit K. PMID: 21858794; PMCID: PMC3346864.
      View in: PubMed   Mentions: 98     Fields:    Translation:Humans
    18. Health literacy, numeracy, and interpretation of graphical breast cancer risk estimates. Patient Educ Couns. 2011 Apr; 83(1):92-8. Brown SM, Culver JO, Osann KE, MacDonald DJ, Sand S, Thornton AA, Grant M, Bowen DJ, Metcalfe KA, Burke HB, Robson ME, Friedman S, Weitzel JN. PMID: 20554149; PMCID: PMC4041683.
      View in: PubMed   Mentions:
    19. Development and evaluation of a decision aid for BRCA carriers with breast cancer. J Genet Couns. 2011 Jun; 20(3):294-307. Culver JO, MacDonald DJ, Thornton AA, Sand SR, Grant M, Bowen DJ, Burke H, Garcia N, Metcalfe KA, Weitzel JN. PMID: 21369831; PMCID: PMC3531556.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    20. Recurrence and variability of germline EPCAM deletions in Lynch syndrome. Hum Mutat. 2011 Apr; 32(4):407-14. Kuiper RP, Vissers LE, Venkatachalam R, Bodmer D, Hoenselaar E, Goossens M, Haufe A, Kamping E, Niessen RC, Hogervorst FB, Gille JJ, Redeker B, Tops CM, van Gijn ME, van den Ouweland AM, Rahner N, Steinke V, Kahl P, Holinski-Feder E, Morak M, Kloor M, Stemmler S, Betz B, Hutter P, Bunyan DJ, Syngal S, Culver JO, Graham T, Chan TL, Nagtegaal ID, van Krieken JH, Schackert HK, Hoogerbrugge N, van Kessel AG, Ligtenberg MJ. PMID: 21309036.
      View in: PubMed   Mentions:
    21. Risk of colorectal and endometrial cancers in EPCAM deletion-positive Lynch syndrome: a cohort study. Lancet Oncol. 2011 Jan; 12(1):49-55. Kempers MJ, Kuiper RP, Ockeloen CW, Chappuis PO, Hutter P, Rahner N, Schackert HK, Steinke V, Holinski-Feder E, Morak M, Kloor M, Büttner R, Verwiel ET, van Krieken JH, Nagtegaal ID, Goossens M, van der Post RS, Niessen RC, Sijmons RH, Kluijt I, Hogervorst FB, Leter EM, Gille JJ, Aalfs CM, Redeker EJ, Hes FJ, Tops CM, van Nesselrooij BP, van Gijn ME, Gómez García EB, Eccles DM, Bunyan DJ, Syngal S, Stoffel EM, Culver JO, Palomares MR, Graham T, Velsher L, Papp J, Oláh E, Chan TL, Leung SY, van Kessel AG, Kiemeney LA, Hoogerbrugge N, Ligtenberg MJ. PMID: 21145788; PMCID: PMC3670774.
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    22. Limited family structure and BRCA gene mutation status in single cases of breast cancer. JAMA. 2007 Jun 20; 297(23):2587-95. Weitzel JN, Lagos VI, Cullinane CA, Gambol PJ, Culver JO, Blazer KR, Palomares MR, Lowstuter KJ, MacDonald DJ. PMID: 17579227.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    23. Results of a randomized study of telephone versus in-person breast cancer risk counseling. Patient Educ Couns. 2006 Dec; 64(1-3):96-103. Helmes AW, Culver JO, Bowen DJ. PMID: 16427245.
      View in: PubMed   Mentions:
    24. Assessing breast cancer risk and BRCA1/2 carrier probability. Breast Dis. 2006-2007; 27:5-20. Culver J, Lowstuter K, Bowling L. PMID: 17917138.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    25. Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors. J Genet Couns. 2004 Apr; 13(2):83-114. Trepanier A, Ahrens M, McKinnon W, Peters J, Stopfer J, Grumet SC, Manley S, Culver JO, Acton R, Larsen-Haidle J, Correia LA, Bennett R, Pettersen B, Ferlita TD, Costalas JW, Hunt K, Donlon S, Skrzynia C, Farrell C, Callif-Daley F, Vockley CW, National Society of Genetic Counselors. PMID: 15604628.
      View in: PubMed   Mentions: 91     Fields:    Translation:Humans
    26. Genetic counseling for women with an intermediate family history of breast cancer. Am J Med Genet. 2000 Feb 28; 90(5):361-8. Burke W, Culver JO, Bowen D, Lowry D, Durfy S, McTiernan A, Andersen MR. PMID: 10706356.
      View in: PubMed   Mentions:
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