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Caryn Lerman

Title(s)Professor of Psychiatry & the Behavioral Sciences
SchoolKeck School of Medicine of USC
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    Other Positions
    Title(s)H. Leslie Hoffman and Elaine S. Hoffman Chair in Cancer Research

    Title(s)Director, USC Norris Comprehensive Cancer Center


    Collapse Overview 
    Collapse Overview
    Dr. Lerman is the H. Leslie and Elaine S. Hoffman Professor in Cancer Research and Director of the USC Norris Comprehensive Cancer Center. Previously, she served as the John H. Glick Professor for Cancer Research and Vice Dean for Strategic Initiatives in the Perelman School of Medicine at the University of Pennsylvania. Prior to her Vice Dean appointment, she served as Senior Deputy Director of the Abramson Cancer Center for 10 years.

    Dr. Lerman is nationally recognized for her cancer prevention research that bridges the fields of neuroscience, pharmacology, genetics and behavioral science. She produced the first empirical data on the outcomes of genetic testing for cancer susceptibility, and was among the first to publish evidence for the genetic basis of cancer risk behaviors. Her pioneering work identifying genetic influences on tobacco use culminated in the first prospective stratified pharmacogenomic trial in the field of tobacco dependence, which has had a considerable impact on the application of precision medicine for tobacco dependence treatment. Supported by her National Cancer Institute (NCI) Outstanding Investigator Award (R35), Dr. Lerman now also leads a highly novel research program that harnesses advances in cognitive neuroscience to promote cancer risk behavior change. She has published over 380 peer reviewed publications, which have been cited over >20,000 times.

    An elected member of the National Academy of Medicine, Dr. Lerman has served as a member of the NCI Board of Scientific Advisors, the National Human Genome Research Advisory Council, and the National Institutes on Drug Abuse Advisory Council. She is also past president of the Society for Research on Nicotine and Tobacco.

    Collapse Research 
    Collapse Research Activities and Funding
    Neural basis of smoking relapse
    NIH/NIDA R01DA041402Apr 1, 2016 - Jan 31, 2021
    Role: Principal Investigator
    Neuroscience-based Interventions for Cancer Risk Behavior Change
    NIH/NCI R35CA197461Aug 1, 2015 - Jul 31, 2022
    Role: Principal Investigator
    UPENN TCORS: Tobacco Product Messaging in a Complex Communication Environment
    NIH/NCI P50CA179546Sep 18, 2013 - Aug 31, 2018
    Role: Co-Principal Investigator
    Retraining Neurocognitive Mechanisms of Cancer Risk Behavior (PQ4)
    NIH/NCI R01CA170297Sep 1, 2012 - Jun 30, 2016
    Role: Principal Investigator
    Cognitive Training for Nicotine Dependence
    NIH/NIDA R01DA030819Sep 30, 2010 - Jun 30, 2015
    Role: Principal Investigator
    Abramson Cancer Center Support Grant
    NIH/NCI P30CA147859Sep 30, 2009 - Sep 29, 2012
    Role: Principal Investigator
    Functional Characterization of OPRM1 A118G in Nicotine Dependence
    NIH/NIDA R21DA027066Sep 30, 2009 - Aug 31, 2011
    Role: Co-Principal Investigator
    Nicotine Abstinence-Induced Cognitive Alterations by COMT Genotype
    NIH/NIDA R03DA027438Sep 15, 2009 - Aug 31, 2012
    Role: Principal Investigator
    Center for Interdisciplinary Research on Nicotine Addiction (CIRNA)
    NIH/NCI P50CA143187Aug 1, 2009 - Jul 31, 2014
    Role: Principal Investigator
    Neural Substrates of Cognitive Deficits in Nicotine Withdrawal
    NIH/NIDA R01DA026849Aug 1, 2009 - May 31, 2013
    Role: Principal Investigator
    Pharmacogenetics of Nicotine Addiction Treatment
    NIH/NIDA U01DA020830Sep 15, 2005 - Jun 30, 2015
    Role: Principal Investigator
    Pharmacogenetic Investigation of Naltrexone
    NIH/NIDA R01DA017555Sep 30, 2003 - Jun 30, 2009
    Role: Principal Investigator
    Transdisciplinary Tobacco Use Research Centers
    NIH/NCI P50CA084718Sep 30, 1999 - Sep 29, 2009
    Role: Principal Investigator
    CANCER GENETICS NETWORK
    NIH/NCI U24CA078146Aug 1, 1998 - Sep 30, 2007
    Role: Co-Principal Investigator
    Decisions &Outcomes of BRCA1/2 Test for Breast Patients
    NIH/NCI R01CA074861Aug 1, 1997 - Jun 30, 2010
    Role: Co-Principal Investigator
    COMPARING MODELS OF COUNSELING FOR BRCA1/2 TESTING
    NIH/NHGRI R01HG001846Sep 30, 1994 - Aug 31, 2002
    Role: Co-Principal Investigator
    COMPARING MODELS OF PRETEST EDUCATION FOR BRCA1 TESTING
    NIH/NIMH R01MH054435Sep 30, 1994 - Aug 31, 1998
    Role: Principal Investigator
    COUNSELING WOMEN AT RISK FOR BREAST CANCER
    NIH/NCI R01CA063605Sep 30, 1993 - Jul 31, 1998
    Role: Principal Investigator
    BIOBEHAVIORAL LUNG CANCER PREVENTION PROGRAM
    NIH/NCI R01CA063562Sep 10, 1993 - May 31, 2004
    Role: Principal Investigator
    IMPROVING ADHERENCE IN WOMEN AT RISK FOR BREAST CANCER
    NIH/NCI R01CA057767Sep 30, 1992 - Feb 28, 1998
    Role: Principal Investigator
    PREVENTIVE ONCOLOGY ACADEMIC AWARD
    NIH/NCI K07CA001604Jul 1, 1991 - Jun 30, 1996
    Role: Principal Investigator
    Abramson Cancer Center Support Grant
    NIH/NCI P30CA016520Dec 1, 1978 - Nov 30, 2020
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. El-Boraie A, Taghavi T, Chenoweth MJ, Fukunaga K, Mushiroda T, Kubo M, Lerman C, Nollen NL, Benowitz NL, Tyndale RF. Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. Addict Biol. 2019 Feb 27. PMID: 30815984.
      View in: PubMed
    2. Robinson JD, Li L, Chen M, Lerman C, Tyndale RF, Schnoll RA, Hawk LW, George TP, Benowitz NL, Cinciripini PM. Evaluating the temporal relationships between withdrawal symptoms and smoking relapse. Psychol Addict Behav. 2019 Jan 07. PMID: 30614717.
      View in: PubMed
    3. Falcone M, Bernardo L, Wileyto EP, Allenby C, Burke AM, Hamilton R, Cristancho M, Ashare RL, Loughead J, Lerman C. Lack of effect of transcranial direct current stimulation (tDCS) on short-term smoking cessation: Results of a randomized, sham-controlled clinical trial. Drug Alcohol Depend. 2019 01 01; 194:244-251. PMID: 30497056.
      View in: PubMed
    4. Mercincavage M, Lochbuehler K, Wileyto EP, Benowitz NL, Tyndale RF, Lerman C, Strasser AA. Association of Reduced Nicotine Content Cigarettes With Smoking Behaviors and Biomarkers of Exposure Among Slow and Fast Nicotine Metabolizers: A Nonrandomized Clinical Trial. JAMA Netw Open. 2018 Aug; 1(4). PMID: 30627706.
      View in: PubMed
    5. Peng AR, Schnoll R, Hawk LW, Cinciripini P, George TP, Lerman C, Tyndale RF. Predicting smoking abstinence with biological and self-report measures of adherence to varenicline: Impact on pharmacogenetic trial outcomes. Drug Alcohol Depend. 2018 09 01; 190:72-81. PMID: 29986268.
      View in: PubMed
    6. Taghavi T, Novalen M, Lerman C, George TP, Tyndale RF. A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine. Cancer Epidemiol Biomarkers Prev. 2018 Aug; 27(8):882-891. PMID: 29853480.
      View in: PubMed
    7. Tanner JA, Zhu AZ, Claw KG, Prasad B, Korchina V, Hu J, Doddapaneni H, Muzny DM, Schuetz EG, Lerman C, Thummel KE, Scherer SE, Tyndale RF. Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics. 2018 Jan; 28(1):7-16. PMID: 29232328.
      View in: PubMed
    8. Peng AR, Le Foll B, Morales M, Lerman C, Schnoll R, Tyndale RF. Improvement of the association between self-reported pill count and varenicline levels following exclusion of participants with misreported pill count: A commentary on Peng et al. (2017). Addict Behav. 2018 Apr; 79:14-16. PMID: 29232593.
      View in: PubMed
    9. Chenoweth MJ, Ware JJ, Zhu AZX, Cole CB, Cox LS, Nollen N, Ahluwalia JS, Benowitz NL, Schnoll RA, Hawk LW, Cinciripini PM, George TP, Lerman C, Knight J, Tyndale RF. Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction. 2018 Mar; 113(3):509-523. PMID: 28921760.
      View in: PubMed
    10. Peng AR, Morales M, Wileyto EP, Hawk LW, Cinciripini P, George TP, Benowitz NL, Nollen NL, Lerman C, Tyndale RF, Schnoll R. Measures and predictors of varenicline adherence in the treatment of nicotine dependence. Addict Behav. 2017 12; 75:122-129. PMID: 28728040.
      View in: PubMed
    11. Loughead J, Falcone M, Wileyto EP, Albelda B, Audrain-McGovern J, Cao W, Kurtz MM, Gur RC, Lerman C. Can brain games help smokers quit?: Results of a randomized clinical trial. Drug Alcohol Depend. 2016 11 01; 168:112-118. PMID: 27635998.
      View in: PubMed
    12. Rabin RA, Ashare RL, Schnoll RA, Cinciripini PM, Hawk LW, Lerman C, Tyndale RF, George TP. Does cannabis use moderate smoking cessation outcomes in treatment-seeking tobacco smokers? Analysis from a large multi-center trial. Am J Addict. 2016 06; 25(4):291-6. PMID: 27187893.
      View in: PubMed
    13. Ross KC, Gubner NR, Tyndale RF, Hawk LW, Lerman C, George TP, Cinciripini P, Schnoll RA, Benowitz NL. Racial differences in the relationship between rate of nicotine metabolism and nicotine intake from cigarette smoking. Pharmacol Biochem Behav. 2016 09; 148:1-7. PMID: 27180107.
      View in: PubMed
    14. Ashare RL, Lerman C, Cao W, Falcone M, Bernardo L, Ruparel K, Hopson R, Gur R, Pruessner JC, Loughead J. Nicotine withdrawal alters neural responses to psychosocial stress. Psychopharmacology (Berl). 2016 07; 233(13):2459-67. PMID: 27087432.
      View in: PubMed
    15. Ashare RL, Lerman C, Tyndale RF, Hawk LW, George TP, Cinciripini P, Schnoll RA. Sleep Disturbance During Smoking Cessation: Withdrawal or Side Effect of Treatment? J Smok Cessat. 2017 Jun; 12(2):63-70. PMID: 28553407.
      View in: PubMed
    16. Allenby CE, Boylan KA, Lerman C, Falcone M. Precision Medicine for Tobacco Dependence: Development and Validation of the Nicotine Metabolite Ratio. J Neuroimmune Pharmacol. 2016 09; 11(3):471-83. PMID: 26872457.
      View in: PubMed
    17. Falcone M, Lee B, Lerman C, Blendy JA. Translational Research on Nicotine Dependence. Curr Top Behav Neurosci. 2016; 28:121-50. PMID: 26873019.
      View in: PubMed
    18. Falcone M, Cao W, Bernardo L, Tyndale RF, Loughead J, Lerman C. Brain Responses to Smoking Cues Differ Based on Nicotine Metabolism Rate. Biol Psychiatry. 2016 08 01; 80(3):190-7. PMID: 26805583.
      View in: PubMed
    19. Webb A, Papp AC, Curtis A, Newman LC, Pietrzak M, Seweryn M, Handelman SK, Rempala GA, Wang D, Graziosa E, Tyndale RF, Lerman C, Kelsoe JR, Mash DC, Sadee W. RNA sequencing of transcriptomes in human brain regions: protein-coding and non-coding RNAs, isoforms and alleles. BMC Genomics. 2015 Nov 23; 16:990. PMID: 26597164; PMCID: PMC4657279.
      View in: PubMed, PubMed Central
    20. Falcone M, Bernardo L, Ashare RL, Hamilton R, Faseyitan O, McKee SA, Loughead J, Lerman C. Transcranial Direct Current Brain Stimulation Increases Ability to Resist Smoking. Brain Stimul. 2016 Mar-Apr; 9(2):191-6. PMID: 26572280; PMCID: PMC4789149 [Available on 03/01/17].
      View in: PubMed, PubMed Central
    21. Dubroff JG, Doot RK, Falcone M, Schnoll RA, Ray R, Tyndale RF, Brody AL, Hou C, Schmitz A, Lerman C. Decreased Nicotinic Receptor Availability in Smokers with Slow Rates of Nicotine Metabolism. J Nucl Med. 2015 Nov; 56(11):1724-9. PMID: 26272810; PMCID: PMC4646418.
      View in: PubMed, PubMed Central
    22. Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE. Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. PLoS One. 2015; 10(7):e0126113. PMID: 26132489; PMCID: PMC4488893.
      View in: PubMed, PubMed Central
    23. Chenoweth MJ, Schnoll RA, Novalen M, Hawk LW, George TP, Cinciripini PM, Lerman C, Tyndale RF. The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio. Nicotine Tob Res. 2016 Apr; 18(4):491-5. PMID: 26069034.
      View in: PubMed
    24. Tyndale RF, Zhu AZ, George TP, Cinciripini P, Hawk LW, Schnoll RA, Swan GE, Benowitz NL, Heitjan DF, Lerman C. Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking. PLoS One. 2015; 10(5):e0128109. PMID: 26010901; PMCID: PMC4444267.
      View in: PubMed, PubMed Central
    25. Tanner JA, Novalen M, Jatlow P, Huestis MA, Murphy SE, Kaprio J, Kankaanpää A, Galanti L, Stefan C, George TP, Benowitz NL, Lerman C, Tyndale RF. Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation. Cancer Epidemiol Biomarkers Prev. 2015 Aug; 24(8):1239-46. PMID: 26014804; PMCID: PMC4526326.
      View in: PubMed, PubMed Central
    26. Perkins KA, Karelitz JL, Michael VC, Fromuth M, Conklin CA, Chengappa KN, Hope C, Lerman C. Initial Evaluation of Fenofibrate for Efficacy in Aiding Smoking Abstinence. Nicotine Tob Res. 2016 Jan; 18(1):74-8. PMID: 25895948; PMCID: PMC4881827 [Available on 01/01/17].
      View in: PubMed, PubMed Central
    27. Hamilton DA, Mahoney MC, Novalen M, Chenoweth MJ, Heitjan DF, Lerman C, Tyndale RF, Hawk LW. Test-Retest Reliability and Stability of the Nicotine Metabolite Ratio Among Treatment-Seeking Smokers. Nicotine Tob Res. 2015 Dec; 17(12):1505-9. PMID: 25732567; PMCID: PMC4654759 [Available on 12/01/16].
      View in: PubMed, PubMed Central
    28. Lerman C, Schnoll RA, Hawk LW, Cinciripini P, George TP, Wileyto EP, Swan GE, Benowitz NL, Heitjan DF, Tyndale RF. Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial. Lancet Respir Med. 2015 Feb; 3(2):131-138. PMID: 25588294; PMCID: PMC4480925.
      View in: PubMed, PubMed Central
    29. Loughead J, Wileyto EP, Ruparel K, Falcone M, Hopson R, Gur R, Lerman C. Working memory-related neural activity predicts future smoking relapse. Neuropsychopharmacology. 2015 May; 40(6):1311-20. PMID: 25469682; PMCID: PMC4397393.
      View in: PubMed, PubMed Central
    30. Chenoweth MJ, Novalen M, Hawk LW, Schnoll RA, George TP, Cinciripini PM, Lerman C, Tyndale RF. Known and novel sources of variability in the nicotine metabolite ratio in a large sample of treatment-seeking smokers. Cancer Epidemiol Biomarkers Prev. 2014 Sep; 23(9):1773-82. PMID: 25012994; PMCID: PMC4154993.
      View in: PubMed, PubMed Central
    31. Lerman C, Gu H, Loughead J, Ruparel K, Yang Y, Stein EA. Large-scale brain network coupling predicts acute nicotine abstinence effects on craving and cognitive function. JAMA Psychiatry. 2014 May; 71(5):523-30. PMID: 24622915; PMCID: PMC4097018.
      View in: PubMed, PubMed Central
    32. Leventhal AM, Lee W, Bergen AW, Swan GE, Tyndale RF, Lerman C, Conti DV. Nicotine dependence as a moderator of genetic influences on smoking cessation treatment outcome. Drug Alcohol Depend. 2014 May 01; 138:109-17. PMID: 24667010; PMCID: PMC4095777.
      View in: PubMed, PubMed Central
    33. David SP, Strong DR, Leventhal AM, Lancaster MA, McGeary JE, Munafò MR, Bergen AW, Swan GE, Benowitz NL, Tyndale RF, Conti DV, Brown RA, Lerman C, Niaura R. Influence of a dopamine pathway additive genetic efficacy score on smoking cessation: results from two randomized clinical trials of bupropion. Addiction. 2013 Dec; 108(12):2202-11. PMID: 23941313; PMCID: PMC3834197.
      View in: PubMed, PubMed Central
    34. Ashare RL, Wileyto EP, Ruparel K, Goelz PM, Hopson RD, Valdez JN, Gur RC, Loughead J, Lerman C. Effects of tolcapone on working memory and brain activity in abstinent smokers: a proof-of-concept study. Drug Alcohol Depend. 2013 Dec 15; 133(3):852-6. PMID: 24095246; PMCID: PMC3960598.
      View in: PubMed, PubMed Central
    35. Perkins KA, Lerman C, Karelitz JL, Jao NC, Chengappa KN, Sparks GM. Sensitivity and specificity of a procedure for early human screening of novel smoking cessation medications. Addiction. 2013 Nov; 108(11):1962-8. PMID: 23773319; PMCID: PMC3797155.
      View in: PubMed, PubMed Central
    36. Falcone M, Smith RM, Chenoweth MJ, Bhattacharjee AK, Kelsoe JR, Tyndale RF, Lerman C. Neuroimaging in psychiatric pharmacogenetics research: the promise and pitfalls. Neuropsychopharmacology. 2013 Nov; 38(12):2327-37. PMID: 23793356; PMCID: PMC3799069.
      View in: PubMed, PubMed Central
    37. Falcone M, Lerman C, Cappella JN, Sanborn P, Jepson C, Strasser AA. No untoward effects of smoking cues in anti-smoking public service announcements. Drug Alcohol Depend. 2013 Nov 01; 133(1):279-82. PMID: 23742844; PMCID: PMC3786034.
      View in: PubMed, PubMed Central
    38. Perkins KA, Karelitz JL, Jao NC, Gur RC, Lerman C. Effects of bupropion on cognitive performance during initial tobacco abstinence. Drug Alcohol Depend. 2013 Nov 01; 133(1):283-6. PMID: 23726977; PMCID: PMC3786016.
      View in: PubMed, PubMed Central
    39. Wang AL, Ruparel K, Loughead JW, Strasser AA, Blady SJ, Lynch KG, Romer D, Cappella JN, Lerman C, Langleben DD. Content matters: neuroimaging investigation of brain and behavioral impact of televised anti-tobacco public service announcements. J Neurosci. 2013 Apr 24; 33(17):7420-7. PMID: 23616548; PMCID: PMC3773220.
      View in: PubMed, PubMed Central
    40. Falcone M, Wileyto EP, Ruparel K, Gerraty RT, LaPrate L, Detre JA, Gur R, Loughead J, Lerman C. Age-related differences in working memory deficits during nicotine withdrawal. Addict Biol. 2014 Sep; 19(5):907-17. PMID: 23496760; PMCID: PMC3701751.
      View in: PubMed, PubMed Central
    41. Bergen AW, Javitz HS, Krasnow R, Nishita D, Michel M, Conti DV, Liu J, Lee W, Edlund CK, Hall S, Kwok PY, Benowitz NL, Baker TB, Tyndale RF, Lerman C, Swan GE. Nicotinic acetylcholine receptor variation and response to smoking cessation therapies. Pharmacogenet Genomics. 2013 Feb; 23(2):94-103. PMID: 23249876; PMCID: PMC3563676.
      View in: PubMed, PubMed Central
    42. Zhu AZ, Renner CC, Hatsukami DK, Swan GE, Lerman C, Benowitz NL, Tyndale RF. The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. Cancer Epidemiol Biomarkers Prev. 2013 Apr; 22(4):708-18. PMID: 23371292; PMCID: PMC3617060.
      View in: PubMed, PubMed Central
    43. Bergen AW, Javitz HS, Su L, He Y, Conti DV, Benowitz NL, Tyndale RF, Lerman C, Swan GE. The DRD4 exon III VNTR, bupropion, and associations with prospective abstinence. Nicotine Tob Res. 2013 Jul; 15(7):1190-200. PMID: 23212438; PMCID: PMC3682839.
      View in: PubMed, PubMed Central
    44. Lee S, Cappella JN, Lerman C, Strasser AA. Effects of smoking cues and argument strength of antismoking advertisements on former smokers' self-efficacy, attitude, and intention to refrain from smoking. Nicotine Tob Res. 2013 Feb; 15(2):527-33. PMID: 22949578; PMCID: PMC3545718.
      View in: PubMed, PubMed Central
    45. Lee W, Ray R, Bergen AW, Swan GE, Thomas P, Tyndale RF, Benowitz NL, Lerman C, Conti DV. DRD1 associations with smoking abstinence across slow and normal nicotine metabolizers. Pharmacogenet Genomics. 2012 Jul; 22(7):551-4. PMID: 22495174; PMCID: PMC3376177.
      View in: PubMed, PubMed Central
    46. Ashare RL, Ray R, Lerman C, Strasser AA. Cognitive effects of the acetylcholinesterase inhibitor, donepezil, in healthy, non-treatment seeking smokers: a pilot feasibility study. Drug Alcohol Depend. 2012 Nov 01; 126(1-2):263-7. PMID: 22595038; PMCID: PMC3424358.
      View in: PubMed, PubMed Central
    47. Javitz HS, Lerman C, Swan GE. Comparative dynamics of four smoking withdrawal symptom scales. Addiction. 2012 Aug; 107(8):1501-11. PMID: 22321019; PMCID: PMC3394903.
      View in: PubMed, PubMed Central
    48. Falcone M, Gold AB, Wileyto EP, Ray R, Ruparel K, Newberg A, Dubroff J, Logan J, Zubieta JK, Blendy JA, Lerman C. µ-Opioid receptor availability in the amygdala is associated with smoking for negative affect relief. Psychopharmacology (Berl). 2012 Aug; 222(4):701-8. PMID: 22389047; PMCID: PMC3670416.
      View in: PubMed, PubMed Central
    49. Gold AB, Wileyto EP, Lori A, Conti D, Cubells JF, Lerman C. Pharmacogenetic association of the galanin receptor (GALR1) SNP rs2717162 with smoking cessation. Neuropsychopharmacology. 2012 Jun; 37(7):1683-8. PMID: 22373943; PMCID: PMC3358736.
      View in: PubMed, PubMed Central
    50. Gold AB, Lerman C. Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes. Hum Genet. 2012 Jan 31. PMID: 22290489.
      View in: PubMed
    51. Schnoll RA, Wileyto EP, Lerman C. Extended duration therapy with transdermal nicotine may attenuate weight gain following smoking cessation. Addict Behav. 2012 Apr; 37(4):565-8. PMID: 22244706; PMCID: PMC3288882.
      View in: PubMed, PubMed Central
    52. King DP, Paciga S, Pickering E, Benowitz NL, Bierut LJ, Conti DV, Kaprio J, Lerman C, Park PW. Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials. Neuropsychopharmacology. 2012 Feb; 37(3):641-50. PMID: 22048466; PMCID: PMC3260990.
      View in: PubMed, PubMed Central
    53. Javitz HS, Swan GE, Lerman C. The dynamics of the urge-to-smoke following smoking cessation via pharmacotherapy. Addiction. 2011 Oct; 106(10):1835-45. PMID: 21561501.
      View in: PubMed
    54. Schnoll RA, Cappella J, Lerman C, Pinto A, Patterson F, Wileyto EP, Bigman C, Leone F. A novel recruitment message to increase enrollment into a smoking cessation treatment program: preliminary results from a randomized trial. Health Commun. 2011 Dec; 26(8):735-42. PMID: 21667366; PMCID: PMC4243839.
      View in: PubMed, PubMed Central
    55. Ray R, Ruparel K, Newberg A, Wileyto EP, Loughead JW, Divgi C, Blendy JA, Logan J, Zubieta JK, Lerman C. Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9268-73. PMID: 21576462; PMCID: PMC3107291.
      View in: PubMed, PubMed Central
    56. Loughead J, Ray R, Wileyto EP, Ruparel K, O'Donnell GP, Senecal N, Siegel S, Gur RC, Lerman C. Brain activity and emotional processing in smokers treated with varenicline. Addict Biol. 2013 Jul; 18(4):732-8. PMID: 21507156.
      View in: PubMed
    57. Falcone M, Jepson C, Benowitz N, Bergen AW, Pinto A, Wileyto EP, Baldwin D, Tyndale RF, Lerman C, Ray R. Association of the nicotine metabolite ratio and CHRNA5/CHRNA3 polymorphisms with smoking rate among treatment-seeking smokers. Nicotine Tob Res. 2011 Jun; 13(6):498-503. PMID: 21385908; PMCID: PMC3103715.
      View in: PubMed, PubMed Central
    58. Lee S, Cappella JN, Lerman C, Strasser AA. Smoking cues, argument strength, and perceived effectiveness of antismoking PSAs. Nicotine Tob Res. 2011 Apr; 13(4):282-90. PMID: 21330273; PMCID: PMC3066405.
      View in: PubMed, PubMed Central
    59. Strasser AA, Benowitz NL, Pinto AG, Tang KZ, Hecht SS, Carmella SG, Tyndale RF, Lerman CE. Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level. Cancer Epidemiol Biomarkers Prev. 2011 Feb; 20(2):234-8. PMID: 21212060; PMCID: PMC3077576.
      View in: PubMed, PubMed Central
    60. Rudnick ND, Strasser AA, Phillips JM, Jepson C, Patterson F, Frey JM, Turetsky BI, Lerman C, Siegel SJ. Mouse model predicts effects of smoking and varenicline on event-related potentials in humans. Nicotine Tob Res. 2010 Jun; 12(6):589-97. PMID: 20395358; PMCID: PMC2878727.
      View in: PubMed, PubMed Central
    61. Wei J, Ma JZ, Payne TJ, Cui W, Ray R, Mitra N, Lerman C, Li MD. Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers. Hum Genet. 2010 Jun; 127(6):691-8. PMID: 20383528.
      View in: PubMed
    62. Perkins KA, Mercincavage M, Fonte CA, Lerman C. Varenicline's effects on acute smoking behavior and reward and their association with subsequent abstinence. Psychopharmacology (Berl). 2010 May; 210(1):45-51. PMID: 20306175; PMCID: PMC2863002.
      View in: PubMed, PubMed Central
    63. Loughead J, Ray R, Wileyto EP, Ruparel K, Sanborn P, Siegel S, Gur RC, Lerman C. Effects of the alpha4beta2 partial agonist varenicline on brain activity and working memory in abstinent smokers. Biol Psychiatry. 2010 Apr 15; 67(8):715-21. PMID: 20207347.
      View in: PubMed
    64. Leader AE, Lerman C, Cappella JN. Nicotine vaccines: will smokers take a shot at quitting? Nicotine Tob Res. 2010 Apr; 12(4):390-7. PMID: 20185516; PMCID: PMC2847077.
      View in: PubMed, PubMed Central
    65. Ray R, Mitra N, Baldwin D, Guo M, Patterson F, Heitjan DF, Jepson C, Wileyto EP, Wei J, Payne T, Ma JZ, Li MD, Lerman C. Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence. Neuropsychopharmacology. 2010 May; 35(6):1374-82. PMID: 20147892; PMCID: PMC2855736.
      View in: PubMed, PubMed Central
    66. Schnoll RA, Patterson F, Wileyto EP, Heitjan DF, Shields AE, Asch DA, Lerman C. Effectiveness of extended-duration transdermal nicotine therapy: a randomized trial. Ann Intern Med. 2010 Feb 02; 152(3):144-51. PMID: 20124230; PMCID: PMC3782858.
      View in: PubMed, PubMed Central
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    80. Patterson F, Jepson C, Strasser AA, Loughead J, Perkins KA, Gur RC, Frey JM, Siegel S, Lerman C. Varenicline improves mood and cognition during smoking abstinence. Biol Psychiatry. 2009 Jan 15; 65(2):144-9. PMID: 18842256; PMCID: PMC2615779.
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