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Jorge Nieva, MD

Title(s)Associate Professor of Clinical Medicine
AddressNOR 1441 Eastlake Ave
Off Campus
Los Angeles CA 90033-9173
Phone+1 323 865 0421
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    Collapse Awards and Honors
    ASCO Award for Excellence in Clinical Trials
    National Cancer Institute Gold Certificate of Excellence
    Outstanding Teacher Award, Scripps Clinic
    Skaggs Scholar in Clinical Science
    Waltz Award for Leadership, Scripps Clinic
    Alpha Omega Alpha Medical Honors Society
    University of California, IrvineDepartment of Medicine Award
    Walter Blumeson Scholarship for Academic Promise
    Irving M. Reingold Prize in Pathology
    Irving M. Reingold Prize in Pathology
    American Association of Pathology Chairs Honor Society
    University of California, Irvine Excellence in Research
    University of California, IrvineDepartmental Honors, Biological Sciences

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    Collapse Overview
    Dr. Jorge Nieva graduated from the University of California, Irvine College of Medicine in 1997, trained in internal medicine at University of California, San Diego and in oncology and hematology at the Scripps Clinic. In 2003 he joined the faculty of the Scripps Research Institute and the medical staff of the Scripps Clinic in La Jolla, CA. While at Scripps, Dr. Nieva pioneered new technology for the detection of cancer cells in the peripheral blood and discoveries related to the fundamental mechanisms of the immune system.

    Dr. Nieva was recruited to the Billings Clinic in Montana in 2007 where he served as department chair and was a program leader who established the multidisciplinary lung cancer and head/neck cancer clinics at the cancer center. While in Billings, Dr. Nieva led efforts to establish a research program in virus-delivered cancer gene therapy and immunotherapy. His teams were awarded certificates for excellence in the conduct of cancer clinical trials from the National Cancer Institute and the American Society of Clinical Oncology. Dr. Nieva returned to California, joining the faculty of the Keck School of Medicine in 2014.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Systematic Review of the Efficacy of Preclinical Models of Lung Cancer Drugs. Front Oncol. 2020; 10:591. Pan E, Bogumil D, Cortessis V, Yu S, Nieva J. PMID: 32391273.
      View in: PubMed   Mentions:
    2. Intravenous 5-fluoro-2'-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2020 May; 85(5):979-993. Coyne GO', Wang L, Zlott J, Juwara L, Covey JM, Beumer JH, Cristea MC, Newman EM, Koehler S, Nieva JJ, Garcia AA, Gandara DR, Miller B, Khin S, Miller SB, Steinberg SM, Rubinstein L, Parchment RE, Kinders RJ, Piekarz RL, Kummar S, Chen AP, Doroshow JH. PMID: 32314030.
      View in: PubMed   Mentions:    Fields:    
    3. Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients. J Mol Diagn. 2020 Mar; 22(3):319-337. Shishido SN, Welter L, Rodriguez-Lee M, Kolatkar A, Xu L, Ruiz C, Gerdtsson AS, Restrepo-Vassalli S, Carlsson A, Larsen J, Greenspan EJ, Hwang ES, Waitman KR, Nieva J, Bethel K, Hicks J, Kuhn P. PMID: 31978562.
      View in: PubMed   Mentions:    Fields:    
    4. Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer. Oncotarget. 2019 Dec 17; 10(66):7016-7030. Gerdtsson AS, Thiele JA, Shishido SN, Zheng S, Schaffer R, Bethel K, Curley S, Lenz HJ, Hanna DL, Nieva J, Kolatkar A, Ruiz C, Rodriguez-Lee M, Oakley Iii GJ, Lee JSH, Hicks J, Kuhn P. PMID: 31903162.
      View in: PubMed   Mentions:    Fields:    
    5. Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials. Lancet Oncol. 2020 02; 21(2):271-282. Doebele RC, Drilon A, Paz-Ares L, Siena S, Shaw AT, Farago AF, Blakely CM, Seto T, Cho BC, Tosi D, Besse B, Chawla SP, Bazhenova L, Krauss JC, Chae YK, Barve M, Garrido-Laguna I, Liu SV, Conkling P, John T, Fakih M, Sigal D, Loong HH, Buchschacher GL, Garrido P, Nieva J, Steuer C, Overbeck TR, Bowles DW, Fox E, Riehl T, Chow-Maneval E, Simmons B, Cui N, Johnson A, Eng S, Wilson TR, Demetri GD. PMID: 31838007.
      View in: PubMed   Mentions: 4     Fields:    
    6. Mandatory Research Biopsy Requirements Delay Initiation of Clinical Trials. Front Oncol. 2019; 9:968. Cheng JH, Tiulim JW, Zhou S, El-Khoueiry A, Nieva J. PMID: 31681560.
      View in: PubMed   Mentions:
    7. A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study. J Thorac Oncol. 2020 01; 15(1):110-119. Schenk EL, Mandrekar SJ, Dy GK, Aubry MC, Tan AD, Dakhil SR, Sachs BA, Nieva JJ, Bertino E, Lee Hann C, Schild SE, Wadsworth TW, Adjei AA, Molina JR. PMID: 31605793.
      View in: PubMed   Mentions: 1     Fields:    
    8. Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer. J Transl Med. 2019 08 28; 17(1):294. Shishido SN, Carlsson A, Nieva J, Bethel K, Hicks JB, Bazhenova L, Kuhn P. PMID: 31462312.
      View in: PubMed   Mentions: 2     Fields:    
    9. Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer. J Thorac Oncol. 2019 11; 14(11):1901-1911. Horn L, Whisenant JG, Wakelee H, Reckamp KL, Qiao H, Leal TA, Du L, Hernandez J, Huang V, Blumenschein GR, Waqar SN, Patel SP, Nieva J, Oxnard GR, Sanborn RE, Shaffer T, Garg K, Holzhausen A, Harrow K, Liang C, Lim LP, Li M, Lovly CM. PMID: 31446141.
      View in: PubMed   Mentions: 1     Fields:    
    10. Patient reported outcomes can improve performance status assessment: a pilot study. J Patient Rep Outcomes. 2019 Jul 16; 3(1):41. Broderick JE, May M, Schwartz JE, Li M, Mejia A, Nocera L, Kolatkar A, Ueno NT, Yennu S, Lee JSH, Hanlon SE, Cozzens Philips FA, Shahabi C, Kuhn P, Nieva J. PMID: 31313047.
      View in: PubMed   Mentions:
    11. Trimodality vs Chemoradiation and Salvage Resection in cN2 Stage IIIA Non-Small Cell Lung Cancer. Semin Thorac Cardiovasc Surg. 2020; 32(1):153-159. Ye JC, Ding L, Atay SM, Nieva JJ, McFadden PM, Chang E, Kim AW. PMID: 31220530.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Detection of NRG1 Gene Fusions in Solid Tumors. Clin Cancer Res. 2019 Aug 15; 25(16):4966-4972. Jonna S, Feldman RA, Swensen J, Gatalica Z, Korn WM, Borghaei H, Ma PC, Nieva JJ, Spira AI, Vanderwalde AM, Wozniak AJ, Kim ES, Liu SV. PMID: 30988082.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Intracellular delivery of mRNA to human primary T cells with microfluidic vortex shedding. Sci Rep. 2019 03 01; 9(1):3214. Jarrell JA, Twite AA, Lau KHWJ, Kashani MN, Lievano AA, Acevedo J, Priest C, Nieva J, Gottlieb D, Pawell RS. PMID: 30824814.
      View in: PubMed   Mentions:    Fields:    
    14. Tuberculosis following PD-1 blockade for cancer immunotherapy. Sci Transl Med. 2019 01 16; 11(475). Barber DL, Sakai S, Kudchadkar RR, Fling SP, Day TA, Vergara JA, Ashkin D, Cheng JH, Lundgren LM, Raabe VN, Kraft CS, Nieva JJ, Cheever MA, Nghiem PT, Sharon E. PMID: 30651320.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    15. Radiomics in Pulmonary Lesion Imaging. AJR Am J Roentgenol. 2019 03; 212(3):497-504. Hassani C, Varghese BA, Nieva J, Duddalwar V. PMID: 30620678.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. A new anion exchange purification method for Cu stable isotopes in blood samples. Anal Bioanal Chem. 2019 Jan; 411(3):765-776. Yang SC, Welter L, Kolatkar A, Nieva J, Waitman KR, Huang KF, Liao WH, Takano S, Berelson WM, West AJ, Kuhn P, John SG. PMID: 30467768.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    17. Low-dimensional dynamical characterization of human performance of cancer patients using motion data. Clin Biomech (Bristol, Avon). 2018 07; 56:61-69. Hasnain Z, Li M, Dorff T, Quinn D, Ueno NT, Yennu S, Kolatkar A, Shahabi C, Nocera L, Nieva J, Kuhn P, Newton PK. PMID: 29803824.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. When it comes to genomic analysis of tumours, don't buy in bulk. Br J Cancer. 2018 05; 118(10):1281-1282. Nieva J, Hicks J. PMID: 29743553.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay. Arch Pathol Lab Med. 2018 Feb; 142(2):198-207. Rodríguez-Lee M, Kolatkar A, McCormick M, Dago AD, Kendall J, Carlsson NA, Bethel K, Greenspan EJ, Hwang SE, Waitman KR, Nieva JJ, Hicks J, Kuhn P. PMID: 29144792.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. Biophysical technologies for understanding circulating tumor cell biology and metastasis. Transl Lung Cancer Res. 2017 Aug; 6(4):473-485. Su DW, Nieva J. PMID: 28904890.
      View in: PubMed   Mentions:
    21. Development of metastatic brain disease involves progression through lung metastases in EGFR mutated non-small cell lung cancer. Converg Sci Phys Oncol. 2017 Sep; 3(3). In G, Mason J, Lin S, Newton PK, Kuhn P, Nieva J. PMID: 30283700.
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    22. Cellular Expression of PD-L1 in the Peripheral Blood of Lung Cancer Patients is Associated with Worse Survival. Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1139-1145. Boffa DJ, Graf RP, Salazar MC, Hoag J, Lu D, Krupa R, Louw J, Dugan L, Wang Y, Landers M, Suraneni M, Greene SB, Magaña M, Makani S, Bazhenova L, Dittamore RV, Nieva J. PMID: 28446544.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. A Randomized Phase II Study of Linsitinib (OSI-906) Versus Topotecan in Patients With Relapsed Small-Cell Lung Cancer. Oncologist. 2016 10; 21(10):1163-1164. Chiappori AA, Otterson GA, Dowlati A, Traynor AM, Horn L, Owonikoko TK, Ross HJ, Hann CL, Abu Hejleh T, Nieva J, Zhao X, Schell M, Sullivan DM. PMID: 27694157.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    24. Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites. NPJ Breast Cancer. 2015; 1:15018. Newton PK, Mason J, Venkatappa N, Jochelson MS, Hurt B, Nieva J, Comen E, Norton L, Kuhn P. PMID: 28721371.
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    25. Oncolytic viruses: perspectives on clinical development. Curr Opin Virol. 2015 Aug; 13:55-60. Burke J, Nieva J, Borad MJ, Breitbach CJ. PMID: 25989094.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    26. A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma. Oral Oncol. 2015 Apr; 51(4):376-82. Gilbert J, Schell MJ, Zhao X, Murphy B, Tanvetyanon T, Leon ME, Neil Hayes D, Haigentz M, Saba N, Nieva J, Bishop J, Sidransky D, Ravi R, Bedi A, Chung CH. PMID: 25593015.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    27. Entropy, complexity, and Markov diagrams for random walk cancer models. Sci Rep. 2014 Dec 19; 4:7558. Newton PK, Mason J, Hurt B, Bethel K, Bazhenova L, Nieva J, Kuhn P. PMID: 25523357.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    28. Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer. J Thorac Oncol. 2014 Aug; 9(8):1111-9. Carlsson A, Nair VS, Luttgen MS, Keu KV, Horng G, Vasanawala M, Kolatkar A, Jamali M, Iagaru AH, Kuschner W, Loo BW, Shrager JB, Bethel K, Hoh CK, Bazhenova L, Nieva J, Kuhn P, Gambhir SS. PMID: 25157764.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    29. Adrenal metastases in lung cancer: clinical implications of a mathematical model. J Thorac Oncol. 2014 Apr; 9(4):442-6. Bazhenova L, Newton P, Mason J, Bethel K, Nieva J, Kuhn P. PMID: 24736064.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer. PLoS One. 2013; 8(7):e67733. Nair VS, Keu KV, Luttgen MS, Kolatkar A, Vasanawala M, Kuschner W, Bethel K, Iagaru AH, Hoh C, Shrager JB, Loo BW, Bazhenova L, Nieva J, Gambhir SS, Kuhn P. PMID: 23861795.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    31. Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients. Cancer. 2013 Jul 01; 119(13):2383-90. Weickhardt AJ, Doebele RC, Purcell WT, Bunn PA, Oton AB, Rothman MS, Wierman ME, Mok T, Popat S, Bauman J, Nieva J, Novello S, Ou SH, Camidge DR. PMID: 23585220.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    32. Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte Carlo mathematical model. Cancer Res. 2013 May 01; 73(9):2760-9. Newton PK, Mason J, Bethel K, Bazhenova L, Nieva J, Norton L, Kuhn P. PMID: 23447576.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    33. Fluid biopsy for solid tumors: a patient's companion for lifelong characterization of their disease. Future Oncol. 2012 Aug; 8(8):989-98. Nieva JJ, Kuhn P. PMID: 22894671.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    34. A pilot study of long-acting octreotide for symptomatic malignant ascites. Oncology. 2012; 82(6):315-20. Jatoi A, Nieva JJ, Qin R, Loprinzi CL, Wos EJ, Novotny PJ, Moore DF, Mowat RB, Bechar N, Pajon ER, Hartmann LC. PMID: 22572824.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. ERCC1 expression in circulating tumor cells (CTCs) using a novel detection platform correlates with progression-free survival (PFS) in patients with metastatic non-small-cell lung cancer (NSCLC) receiving platinum chemotherapy. Lung Cancer. 2012 Aug; 77(2):421-6. Das M, Riess JW, Frankel P, Schwartz E, Bennis R, Hsieh HB, Liu X, Ly JC, Zhou L, Nieva JJ, Wakelee HA, Bruce RH. PMID: 22555222.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    36. A stochastic Markov chain model to describe lung cancer growth and metastasis. PLoS One. 2012; 7(4):e34637. Newton PK, Mason J, Bethel K, Bazhenova LA, Nieva J, Kuhn P. PMID: 22558094.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    37. Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors. Phys Biol. 2012 Feb; 9(1):016001. Cho EH, Wendel M, Luttgen M, Yoshioka C, Marrinucci D, Lazar D, Schram E, Nieva J, Bazhenova L, Morgan A, Ko AH, Korn WM, Kolatkar A, Bethel K, Kuhn P. PMID: 22306705.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    38. High-definition imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis. Phys Biol. 2012 Feb; 9(1):016004. Nieva J, Wendel M, Luttgen MS, Marrinucci D, Bazhenova L, Kolatkar A, Santala R, Whittenberger B, Burke J, Torrey M, Bethel K, Kuhn P. PMID: 22306961.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCellsCTClinical Trials
    39. Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers. Phys Biol. 2012 Feb; 9(1):016003. Marrinucci D, Bethel K, Kolatkar A, Luttgen MS, Malchiodi M, Baehring F, Voigt K, Lazar D, Nieva J, Bazhenova L, Ko AH, Korn WM, Schram E, Coward M, Yang X, Metzner T, Lamy R, Honnatti M, Yoshioka C, Kunken J, Petrova Y, Sok D, Nelson D, Kuhn P. PMID: 22306768.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansCells
    40. Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology. Phys Biol. 2012 Feb; 9(1):016005. Wendel M, Bazhenova L, Boshuizen R, Kolatkar A, Honnatti M, Cho EH, Marrinucci D, Sandhu A, Perricone A, Thistlethwaite P, Bethel K, Nieva J, Heuvel Mv, Kuhn P. PMID: 22307026.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCellsCTClinical Trials
    41. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature. 2011 Aug 31; 477(7362):99-102. Breitbach CJ, Burke J, Jonker D, Stephenson J, Haas AR, Chow LQ, Nieva J, Hwang TH, Moon A, Patt R, Pelusio A, Le Boeuf F, Burns J, Evgin L, De Silva N, Cvancic S, Robertson T, Je JE, Lee YS, Parato K, Diallo JS, Fenster A, Daneshmand M, Bell JC, Kirn DH. PMID: 21886163.
      View in: PubMed   Mentions: 178     Fields:    Translation:HumansCellsCTClinical Trials
    42. Cholesterol secosterol aldehydes induce amyloidogenesis and dysfunction of wild-type tumor protein p53. Chem Biol. 2011 Jul 29; 18(7):920-7. Nieva J, Song BD, Rogel JK, Kujawara D, Altobel L, Izharrudin A, Boldt GE, Grover RK, Wentworth AD, Wentworth P. PMID: 21802012.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. Cytomorphology of circulating colorectal tumor cells:a small case series. J Oncol. 2010; 2010:861341. Marrinucci D, Bethel K, Lazar D, Fisher J, Huynh E, Clark P, Bruce R, Nieva J, Kuhn P. PMID: 20111743.
      View in: PubMed   Mentions:
    44. Circulating tumor cells from well-differentiated lung adenocarcinoma retain cytomorphologic features of primary tumor type. Arch Pathol Lab Med. 2009 Sep; 133(9):1468-71. Marrinucci D, Bethel K, Luttgen M, Bruce RH, Nieva J, Kuhn P. PMID: 19722757.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    45. The ratio of cholesterol 5,6-secosterols formed from ozone and singlet oxygen offers insight into the oxidation of cholesterol in vivo. Chem Commun (Camb). 2009 Jun 07; (21):3098-100. Wentworth AD, Song BD, Nieva J, Shafton A, Tripurenani S, Wentworth P. PMID: 19462099.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    46. Purification and characterization of sideroblasts from patients with acquired and hereditary sideroblastic anaemia. Br J Haematol. 2008 Nov; 143(3):446-50. Martin FM, Prchal J, Nieva J, Saven A, Andrey J, Bethel K, Barton JC, Aripally G, Bottomley SS, Friedman JS. PMID: 18729851.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    47. Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation. Biochemistry. 2008 Jul 22; 47(29):7695-705. Nieva J, Shafton A, Altobell LJ, Tripuraneni S, Rogel JK, Wentworth AD, Lerner RA, Wentworth P. PMID: 18578541.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    48. Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients. Thromb Res. 2008; 122(5):604-9. Tilley RE, Holscher T, Belani R, Nieva J, Mackman N. PMID: 18262600.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    49. Understanding hairy cell leukemia genetics. Leuk Lymphoma. 2007 Apr; 48(4):653-4. Nieva J, Saven A. PMID: 17454620.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    50. The clinical significance of circulating tissue factor in prostate cancer. Thromb Haemost. 2007 Mar; 97(3):329-30. Nieva J. PMID: 17334495.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Case study of the morphologic variation of circulating tumor cells. Hum Pathol. 2007 Mar; 38(3):514-9. Marrinucci D, Bethel K, Bruce RH, Curry DN, Hsieh B, Humphrey M, Krivacic RT, Kroener J, Kroener L, Ladanyi A, Lazarus NH, Nieva J, Kuhn P. PMID: 17188328.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    52. AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. N Engl J Med. 2006 Oct 19; 355(16):1672-81. Bussel JB, Kuter DJ, George JN, McMillan R, Aledort LM, Conklin GT, Lichtin AE, Lyons RM, Nieva J, Wasser JS, Wiznitzer I, Kelly R, Chen CF, Nichol JL. PMID: 17050891.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansCTClinical Trials
    53. Use of optophoresis as an in vitro predictor of cell response to chemotherapy for chronic lymphocytic leukemia. Leuk Lymphoma. 2006 Oct; 47(10):2194-202. Nerenberg M, Kariv I, McNeeley P, Marchand P, Sur S, Diver J, Riccitelli S, Nieva J, Saven A. PMID: 17071495.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    54. Proatherogenic effects of the cholesterol ozonolysis products, atheronal-A and atheronal-B. Biochemistry. 2006 Jun 13; 45(23):7162-70. Takeuchi C, Galvé R, Nieva J, Witter DP, Wentworth AD, Troseth RP, Lerner RA, Wentworth P. PMID: 16752907.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    55. Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nat Chem Biol. 2006 May; 2(5):249-53. Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. PMID: 16565714.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    56. High speed detection of circulating tumor cells. Biosens Bioelectron. 2006 Apr 15; 21(10):1893-9. Hsieh HB, Marrinucci D, Bethel K, Curry DN, Humphrey M, Krivacic RT, Kroener J, Kroener L, Ladanyi A, Lazarus N, Kuhn P, Bruce RH, Nieva J. PMID: 16464570.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    57. Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway. Immunol Lett. 2006 Feb 28; 103(1):33-8. Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P. PMID: 16386801.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    58. SHP1 expression in bone marrow biopsies of myelodysplastic syndrome patients: a new prognostic factor. Br J Haematol. 2005 Jun; 129(6):791-4. Mena-Duran AV, Togo SH, Bazhenova L, Cervera J, Bethel K, Senent ML, Nieva J, Sanz GF, Sanz MA, Saven A, Mustelin T. PMID: 15953006.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    59. The antibody-catalyzed water oxidation pathway--a new chemical arm to immune defense? Trends Biochem Sci. 2004 May; 29(5):274-8. Nieva J, Wentworth P. PMID: 15130564.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    60. Metabolite-initiated protein misfolding may trigger Alzheimer's disease. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):4752-7. Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P, Lerner RA, Kelly JW. PMID: 15034169.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    61. Cladribine activity in systemic mast cell disease: application of biochemistry in the modern era of molecular biology. Leuk Res. 2004 Feb; 28(2):113-4. Nieva J, Saven A. PMID: 14654073.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    62. Evidence for ozone formation in human atherosclerotic arteries. Science. 2003 Nov 07; 302(5647):1053-6. Wentworth P, Nieva J, Takeuchi C, Galve R, Wentworth AD, Dilley RB, DeLaria GA, Saven A, Babior BM, Janda KD, Eschenmoser A, Lerner RA. PMID: 14605372.
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