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TRUST-II: a global phase II study of taletrectinib in ROS1-positive non-small-cell lung cancer and other solid tumors. Future Oncol. 2023 Mar 06.
Nagasaka M, Ohe Y, Zhou C, Choi CM, Yang N, Liu G, Felip E, P?rol M, Besse B, Nieva J, Raez L, Pennell NA, Dimou A, Marinis F, Ciardiello F, Seto T, Hu Z, Pan M, Wang W, Li S, Ou SI. PMID: 36877099.
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PubMed Mentions: Fields:
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Understanding KRAS for better targeting. Transl Lung Cancer Res. 2023 Feb 28; 12(2):181-183.
Patel R, Nieva J. PMID: 36895917; PMCID: PMC9989813.
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PubMed Mentions:
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A Multicenter Retrospective Chart Review of Clinical Outcomes Among Patients With KRAS G12C Mutant Non-Small Cell Lung Cancer. Clin Lung Cancer. 2023 Feb 08.
Iams WT, Balbach ML, Phillips S, Sacher A, Bestvina C, Velcheti V, Wang X, Marmarelis ME, Sethakorn N, Leal T, Sackstein PE, Kim C, Robinson MA, Mehta K, Hsu R, Nieva J, Patil T, Camidge DR. PMID: 36841727.
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PubMed Mentions: Fields:
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Characterization of mortality and high-risk characteristics of thyroid cancer in Filipinos using the California Cancer Registry. Front Public Health. 2022; 10:1104607.
Hsu R, Tsai KY, Chennapan K, Wojcik KY, Lee AW, Nieva JJ, Liu L. PMID: 36743179; PMCID: PMC9893642.
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PubMed Mentions: Fields:
Translation:
Humans
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Multianalyte liquid biopsy to aid the diagnostic workup of breast cancer. NPJ Breast Cancer. 2022 Sep 27; 8(1):112.
Setayesh SM, Hart O, Naghdloo A, Higa N, Nieva J, Lu J, Hwang S, Wilkinson K, Kidd M, Anderson A, Velasco CR, Kolatkar A, Matsumoto N, Nevarez R, Hicks JB, Mason J, Shishido SN, Kuhn P. PMID: 36167819; PMCID: PMC9515081.
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PubMed Mentions:
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Evaluating Real World Mutational Differences Between Hispanics and Asians in NSCLC at a Large Academic Institution in Los Angeles. Clin Lung Cancer. 2022 11; 23(7):e443-e452.
Hsu R, Herrmann A, Gaur K, Xia B, Nieva JJ. PMID: 35902325.
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Translation:
Humans
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Retrospective Analysis of Real-World Management of EGFR-Mutated Advanced NSCLC, After First-Line EGFR-TKI Treatment: US Treatment Patterns, Attrition, and Survival Data. Drugs Real World Outcomes. 2022 Sep; 9(3):333-345.
Nieva J, Reckamp KL, Potter D, Taylor A, Sun P. PMID: 35661118; PMCID: PMC9392819.
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PubMed Mentions:
1
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Effect of sponsor on enrollment criteria in non-small cell lung cancer clinical trials. J Cancer Policy. 2022 09; 33:100336.
Cooper RA, Chai Y, Nieva J. PMID: 35605888.
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PubMed Mentions: Fields:
Translation:
Humans
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Characterization of Cellular and Acellular Analytes from Pre-Cystectomy Liquid Biopsies in Patients Newly Diagnosed with Primary Bladder Cancer. Cancers (Basel). 2022 Feb 01; 14(3).
Shishido SN, Sayeed S, Courcoubetis G, Djaladat H, Miranda G, Pienta KJ, Nieva J, Hansel DE, Desai M, Gill IS, Kuhn P, Mason J. PMID: 35159025; PMCID: PMC8833768.
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PubMed Mentions:
5
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Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas. Oncotarget. 2021 Dec 07; 12(25):2449-2458.
Hsu R, Baca Y, Xiu J, Wang R, Bodor JN, Kim C, Khan H, Mamdani H, Nagasaka M, Puri S, Liu SV, Korn WM, Nieva JJ. PMID: 34917263; PMCID: PMC8664394.
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PubMed Mentions:
3 Fields:
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Characterization of KRAS Mutation Subtypes in Non-small Cell Lung Cancer. Mol Cancer Ther. 2021 12; 20(12):2577-2584.
Judd J, Abdel Karim N, Khan H, Naqash AR, Baca Y, Xiu J, VanderWalde AM, Mamdani H, Raez LE, Nagasaka M, Pai SG, Socinski MA, Nieva JJ, Kim C, Wozniak AJ, Ikpeazu C, de Lima Lopes G, Spira AI, Korn WM, Kim ES, Liu SV, Borghaei H. PMID: 34518295; PMCID: PMC9662933.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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NTRK1 Fusions identified by non-invasive plasma next-generation sequencing (NGS) across 9 cancer types. Br J Cancer. 2022 02; 126(3):514-520.
Rolfo C, Drilon A, Hong D, McCoach C, Dowlati A, Lin JJ, Russo A, Schram AM, Liu SV, Nieva JJ, Nguyen T, Eshaghian S, Morse M, Gettinger S, Mobayed M, Goldberg S, Araujo-Mino E, Vidula N, Bardia A, Subramanian J, Sashital D, Stinchcombe T, Kiedrowski L, Price K, Gandara DR. PMID: 34480094; PMCID: PMC8811064.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC). Lung Cancer. 2021 10; 160:92-98.
Nagasaka M, Asad MFB, Al Hallak MN, Uddin MH, Sukari A, Baca Y, Xiu J, Magee D, Mamdani H, Uprety D, Kim C, Xia B, Liu SV, Nieva JJ, Lopes G, Bepler G, Borghaei H, Demeure MJ, Raez LE, Ma PC, Puri S, Korn WM, Azmi AS. PMID: 34482103; PMCID: PMC8853639.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Blood-Based Multi-Cancer Detection Using a Novel Variant Calling Assay (DEEPGENTM): Early Clinical Results. Cancers (Basel). 2021 Aug 15; 13(16).
Ris F, Hellan M, Douissard J, Nieva JJ, Triponez F, Woo Y, Geller D, Buchs NC, Buehler L, Moenig S, Iselin CE, Karenovics W, Petignat P, Lam GT, Undurraga Malinervo M, Tuttle R, Ouellette J, Bose D, Ismail N, Toso C. PMID: 34439258; PMCID: PMC8392437.
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PubMed Mentions:
1
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Clinical management of immune-related adverse events following immunotherapy treatment in patients with non-small cell lung cancer. J Investig Med. 2021 10; 69(7):1281-1286.
Green HE, Nieva J. PMID: 34127515; PMCID: PMC8478790.
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PubMed Mentions: Fields:
Translation:
Humans
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Effect of prior therapy on tumor mutational burden in NSCLC. Transl Lung Cancer Res. 2021 Mar; 10(3):1231-1238.
Jonna S, Vanderwalde A, Nieva J, Poorman KA, Saul M, von Buttlar X, Hu JY, Liu SV. PMID: 33889505; PMCID: PMC8044473.
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PubMed Mentions:
1
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Treatment response and tumor evolution: lessons from an extended series of multianalyte liquid biopsies in a metastatic breast cancer patient. Cold Spring Harb Mol Case Stud. 2020 12; 6(6).
Welter L, Xu L, McKinley D, Dago AE, Prabakar RK, Restrepo-Vassalli S, Xu K, Rodriguez-Lee M, Kolatkar A, Nevarez R, Ruiz C, Nieva J, Kuhn P, Hicks J. PMID: 33203646; PMCID: PMC7784493.
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PubMed Mentions:
15 Fields:
Translation:
Cells
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Use of Wearable Activity Tracker in Patients With Cancer Undergoing Chemotherapy: Toward Evaluating Risk of Unplanned Health Care Encounters. JCO Clin Cancer Inform. 2020 09; 4:839-853.
Nilanon T, Nocera LP, Martin AS, Kolatkar A, May M, Hasnain Z, Ueno NT, Yennu S, Alexander A, Mejia AE, Boles RW, Li M, Lee JSH, Hanlon SE, Cozzens Philips FA, Quinn DI, Newton PK, Broderick J, Shahabi C, Kuhn P, Nieva JJ. PMID: 32970482; PMCID: PMC7531613.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Quantified Kinematics to Evaluate Patient Chemotherapy Risks in Clinic. JCO Clin Cancer Inform. 2020 06; 4:583-601.
Hasnain Z, Nilanon T, Li M, Mejia A, Kolatkar A, Nocera L, Shahabi C, Cozzens Philips FA, Lee JSH, Hanlon SE, Vaidya P, Ueno NT, Yennu S, Newton PK, Kuhn P, Nieva J. PMID: 32598179; PMCID: PMC7328110.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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A Systematic Review of the Efficacy of Preclinical Models of Lung Cancer Drugs. Front Oncol. 2020; 10:591.
Pan E, Bogumil D, Cortessis V, Yu S, Nieva J. PMID: 32391273; PMCID: PMC7190806.
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PubMed Mentions:
6
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Intravenous 5-fluoro-2'-deoxycytidine administered with tetrahydrouridine increases the proportion of p16-expressing circulating tumor cells in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2020 05; 85(5):979-993.
Coyne GO', Wang L, Zlott J, Juwara L, Covey JM, Beumer JH, Cristea MC, Newman EM, Koehler S, Nieva JJ, Garcia AA, Gandara DR, Miller B, Khin S, Miller SB, Steinberg SM, Rubinstein L, Parchment RE, Kinders RJ, Piekarz RL, Kummar S, Chen AP, Doroshow JH. PMID: 32314030; PMCID: PMC7188725.
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PubMed Mentions:
6 Fields:
Translation:
HumansCellsCTClinical Trials
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Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients. J Mol Diagn. 2020 03; 22(3):319-337.
Shishido SN, Welter L, Rodriguez-Lee M, Kolatkar A, Xu L, Ruiz C, Gerdtsson AS, Restrepo-Vassalli S, Carlsson A, Larsen J, Greenspan EJ, Hwang ES, Waitman KR, Nieva J, Bethel K, Hicks J, Kuhn P. PMID: 31978562; PMCID: PMC7103765.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer. Oncotarget. 2019 Dec 17; 10(66):7016-7030.
Gerdtsson AS, Thiele JA, Shishido SN, Zheng S, Schaffer R, Bethel K, Curley S, Lenz HJ, Hanna DL, Nieva J, Kolatkar A, Ruiz C, Rodriguez-Lee M, Oakley Iii GJ, Lee JSH, Hicks J, Kuhn P. PMID: 31903162; PMCID: PMC6925029.
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PubMed Mentions:
8 Fields:
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Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials. Lancet Oncol. 2020 02; 21(2):271-282.
Doebele RC, Drilon A, Paz-Ares L, Siena S, Shaw AT, Farago AF, Blakely CM, Seto T, Cho BC, Tosi D, Besse B, Chawla SP, Bazhenova L, Krauss JC, Chae YK, Barve M, Garrido-Laguna I, Liu SV, Conkling P, John T, Fakih M, Sigal D, Loong HH, Buchschacher GL, Garrido P, Nieva J, Steuer C, Overbeck TR, Bowles DW, Fox E, Riehl T, Chow-Maneval E, Simmons B, Cui N, Johnson A, Eng S, Wilson TR, Demetri GD, trial investigators. PMID: 31838007; PMCID: PMC7461630.
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PubMed Mentions:
347 Fields:
Translation:
Humans
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Mandatory Research Biopsy Requirements Delay Initiation of Clinical Trials. Front Oncol. 2019; 9:968.
Cheng JH, Tiulim JW, Zhou S, El-Khoueiry A, Nieva J. PMID: 31681560; PMCID: PMC6813196.
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PubMed Mentions:
4
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A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study. J Thorac Oncol. 2020 01; 15(1):110-119.
Schenk EL, Mandrekar SJ, Dy GK, Aubry MC, Tan AD, Dakhil SR, Sachs BA, Nieva JJ, Bertino E, Lee Hann C, Schild SE, Wadsworth TW, Adjei AA, Molina JR. PMID: 31605793; PMCID: PMC7279615.
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PubMed Mentions:
25 Fields:
Translation:
HumansCellsCTClinical Trials
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Circulating tumor cells as a response monitor in stage IV non-small cell lung cancer. J Transl Med. 2019 08 28; 17(1):294.
Shishido SN, Carlsson A, Nieva J, Bethel K, Hicks JB, Bazhenova L, Kuhn P. PMID: 31462312; PMCID: PMC6714097.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Monitoring Therapeutic Response and Resistance: Analysis of Circulating Tumor DNA in Patients With ALK+ Lung Cancer. J Thorac Oncol. 2019 11; 14(11):1901-1911.
Horn L, Whisenant JG, Wakelee H, Reckamp KL, Qiao H, Leal TA, Du L, Hernandez J, Huang V, Blumenschein GR, Waqar SN, Patel SP, Nieva J, Oxnard GR, Sanborn RE, Shaffer T, Garg K, Holzhausen A, Harrow K, Liang C, Lim LP, Li M, Lovly CM. PMID: 31446141; PMCID: PMC6823161.
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PubMed Mentions:
52 Fields:
Translation:
HumansCTClinical Trials
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Patient reported outcomes can improve performance status assessment: a pilot study. J Patient Rep Outcomes. 2019 Jul 16; 3(1):41.
Broderick JE, May M, Schwartz JE, Li M, Mejia A, Nocera L, Kolatkar A, Ueno NT, Yennu S, Lee JSH, Hanlon SE, Cozzens Philips FA, Shahabi C, Kuhn P, Nieva J. PMID: 31313047; PMCID: PMC6635569.
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PubMed Mentions:
8
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Trimodality vs Chemoradiation and Salvage Resection in cN2 Stage IIIA Non-Small Cell Lung Cancer. Semin Thorac Cardiovasc Surg. 2020; 32(1):153-159.
Ye JC, Ding L, Atay SM, Nieva JJ, McFadden PM, Chang E, Kim AW. PMID: 31220530; PMCID: PMC7517707.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Detection of NRG1 Gene Fusions in Solid Tumors. Clin Cancer Res. 2019 Aug 15; 25(16):4966-4972.
Jonna S, Feldman RA, Swensen J, Gatalica Z, Korn WM, Borghaei H, Ma PC, Nieva JJ, Spira AI, Vanderwalde AM, Wozniak AJ, Kim ES, Liu SV. PMID: 30988082; PMCID: PMC7470623.
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PubMed Mentions:
62 Fields:
Translation:
Humans
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Tuberculosis following PD-1 blockade for cancer immunotherapy. Sci Transl Med. 2019 01 16; 11(475).
Barber DL, Sakai S, Kudchadkar RR, Fling SP, Day TA, Vergara JA, Ashkin D, Cheng JH, Lundgren LM, Raabe VN, Kraft CS, Nieva JJ, Cheever MA, Nghiem PT, Sharon E. PMID: 30651320; PMCID: PMC7372940.
View in:
PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Radiomics in Pulmonary Lesion Imaging. AJR Am J Roentgenol. 2019 03; 212(3):497-504.
Hassani C, Varghese BA, Nieva J, Duddalwar V. PMID: 30620678.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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A new anion exchange purification method for Cu stable isotopes in blood samples. Anal Bioanal Chem. 2019 Jan; 411(3):765-776.
Yang SC, Welter L, Kolatkar A, Nieva J, Waitman KR, Huang KF, Liao WH, Takano S, Berelson WM, West AJ, Kuhn P, John SG. PMID: 30467768; PMCID: PMC7450686.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Low-dimensional dynamical characterization of human performance of cancer patients using motion data. Clin Biomech (Bristol, Avon). 2018 07; 56:61-69.
Hasnain Z, Li M, Dorff T, Quinn D, Ueno NT, Yennu S, Kolatkar A, Shahabi C, Nocera L, Nieva J, Kuhn P, Newton PK. PMID: 29803824; PMCID: PMC7519623.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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When it comes to genomic analysis of tumours, don't buy in bulk. Br J Cancer. 2018 05; 118(10):1281-1282.
Nieva J, Hicks J. PMID: 29743553; PMCID: PMC5959923.
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PubMed Mentions: Fields:
Translation:
Humans
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Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay. Arch Pathol Lab Med. 2018 Feb; 142(2):198-207.
Rodr?guez-Lee M, Kolatkar A, McCormick M, Dago AD, Kendall J, Carlsson NA, Bethel K, Greenspan EJ, Hwang SE, Waitman KR, Nieva JJ, Hicks J, Kuhn P. PMID: 29144792; PMCID: PMC7679174.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Biophysical technologies for understanding circulating tumor cell biology and metastasis. Transl Lung Cancer Res. 2017 Aug; 6(4):473-485.
Su DW, Nieva J. PMID: 28904890; PMCID: PMC5583073.
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PubMed Mentions:
7
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Development of metastatic brain disease involves progression through lung metastases in EGFR mutated non-small cell lung cancer. Converg Sci Phys Oncol. 2017 Sep; 3(3).
In G, Mason J, Lin S, Newton PK, Kuhn P, Nieva J. PMID: 30283700; PMCID: PMC6166474.
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PubMed Mentions:
3
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Cellular Expression of PD-L1 in the Peripheral Blood of Lung Cancer Patients is Associated with Worse Survival. Cancer Epidemiol Biomarkers Prev. 2017 07; 26(7):1139-1145.
Boffa DJ, Graf RP, Salazar MC, Hoag J, Lu D, Krupa R, Louw J, Dugan L, Wang Y, Landers M, Suraneni M, Greene SB, Magaña M, Makani S, Bazhenova L, Dittamore RV, Nieva J. PMID: 28446544; PMCID: PMC5500408.
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PubMed Mentions:
41 Fields:
Translation:
HumansCells
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A Randomized Phase II Study of Linsitinib (OSI-906) Versus Topotecan in Patients With Relapsed Small-Cell Lung Cancer. Oncologist. 2016 10; 21(10):1163-1164.
Chiappori AA, Otterson GA, Dowlati A, Traynor AM, Horn L, Owonikoko TK, Ross HJ, Hann CL, Abu Hejleh T, Nieva J, Zhao X, Schell M, Sullivan DM. PMID: 27694157; PMCID: PMC5061534.
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PubMed Mentions:
17 Fields:
Translation:
HumansCTClinical Trials
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Spatiotemporal progression of metastatic breast cancer: a Markov chain model highlighting the role of early metastatic sites. NPJ Breast Cancer. 2015; 1:15018.
Newton PK, Mason J, Venkatappa N, Jochelson MS, Hurt B, Nieva J, Comen E, Norton L, Kuhn P. PMID: 28721371; PMCID: PMC5515198.
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PubMed Mentions:
16
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Oncolytic viruses: perspectives on clinical development. Curr Opin Virol. 2015 Aug; 13:55-60.
Burke J, Nieva J, Borad MJ, Breitbach CJ. PMID: 25989094.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma. Oral Oncol. 2015 Apr; 51(4):376-82.
Gilbert J, Schell MJ, Zhao X, Murphy B, Tanvetyanon T, Leon ME, Neil Hayes D, Haigentz M, Saba N, Nieva J, Bishop J, Sidransky D, Ravi R, Bedi A, Chung CH. PMID: 25593015; PMCID: PMC4459134.
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PubMed Mentions:
18 Fields:
Translation:
HumansCTClinical Trials
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Entropy, complexity, and Markov diagrams for random walk cancer models. Sci Rep. 2014 Dec 19; 4:7558.
Newton PK, Mason J, Hurt B, Bethel K, Bazhenova L, Nieva J, Kuhn P. PMID: 25523357; PMCID: PMC4894412.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer. J Thorac Oncol. 2014 Aug; 9(8):1111-9.
Carlsson A, Nair VS, Luttgen MS, Keu KV, Horng G, Vasanawala M, Kolatkar A, Jamali M, Iagaru AH, Kuschner W, Loo BW, Shrager JB, Bethel K, Hoh CK, Bazhenova L, Nieva J, Kuhn P, Gambhir SS. PMID: 25157764; PMCID: PMC4145608.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Adrenal metastases in lung cancer: clinical implications of a mathematical model. J Thorac Oncol. 2014 Apr; 9(4):442-6.
Bazhenova L, Newton P, Mason J, Bethel K, Nieva J, Kuhn P. PMID: 24736064; PMCID: PMC3989547.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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An observational study of circulating tumor cells and (18)F-FDG PET uptake in patients with treatment-naive non-small cell lung cancer. PLoS One. 2013; 8(7):e67733.
Nair VS, Keu KV, Luttgen MS, Kolatkar A, Vasanawala M, Kuschner W, Bethel K, Iagaru AH, Hoh C, Shrager JB, Loo BW, Bazhenova L, Nieva J, Gambhir SS, Kuhn P. PMID: 23861795; PMCID: PMC3702496.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Symptomatic reduction in free testosterone levels secondary to crizotinib use in male cancer patients. Cancer. 2013 Jul 01; 119(13):2383-90.
Weickhardt AJ, Doebele RC, Purcell WT, Bunn PA, Oton AB, Rothman MS, Wierman ME, Mok T, Popat S, Bauman J, Nieva J, Novello S, Ou SH, Camidge DR. PMID: 23585220; PMCID: PMC3686910.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Spreaders and sponges define metastasis in lung cancer: a Markov chain Monte Carlo mathematical model. Cancer Res. 2013 May 01; 73(9):2760-9.
Newton PK, Mason J, Bethel K, Bazhenova L, Nieva J, Norton L, Kuhn P. PMID: 23447576; PMCID: PMC3644026.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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Fluid biopsy for solid tumors: a patient's companion for lifelong characterization of their disease. Future Oncol. 2012 Aug; 8(8):989-98.
Nieva JJ, Kuhn P. PMID: 22894671; PMCID: PMC3658625.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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A pilot study of long-acting octreotide for symptomatic malignant ascites. Oncology. 2012; 82(6):315-20.
Jatoi A, Nieva JJ, Qin R, Loprinzi CL, Wos EJ, Novotny PJ, Moore DF, Mowat RB, Bechar N, Pajon ER, Hartmann LC. PMID: 22572824; PMCID: PMC3559024.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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ERCC1 expression in circulating tumor cells (CTCs) using a novel detection platform correlates with progression-free survival (PFS) in patients with metastatic non-small-cell lung cancer (NSCLC) receiving platinum chemotherapy. Lung Cancer. 2012 Aug; 77(2):421-6.
Das M, Riess JW, Frankel P, Schwartz E, Bennis R, Hsieh HB, Liu X, Ly JC, Zhou L, Nieva JJ, Wakelee HA, Bruce RH. PMID: 22555222.
View in:
PubMed Mentions:
25 Fields:
Translation:
HumansCells
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A stochastic Markov chain model to describe lung cancer growth and metastasis. PLoS One. 2012; 7(4):e34637.
Newton PK, Mason J, Bethel K, Bazhenova LA, Nieva J, Kuhn P. PMID: 22558094; PMCID: PMC3338733.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors. Phys Biol. 2012 Feb; 9(1):016001.
Cho EH, Wendel M, Luttgen M, Yoshioka C, Marrinucci D, Lazar D, Schram E, Nieva J, Bazhenova L, Morgan A, Ko AH, Korn WM, Kolatkar A, Bethel K, Kuhn P. PMID: 22306705; PMCID: PMC3387999.
View in:
PubMed Mentions:
102 Fields:
Translation:
HumansCells
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High-definition imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis. Phys Biol. 2012 Feb; 9(1):016004.
Nieva J, Wendel M, Luttgen MS, Marrinucci D, Bazhenova L, Kolatkar A, Santala R, Whittenberger B, Burke J, Torrey M, Bethel K, Kuhn P. PMID: 22306961; PMCID: PMC3388002.
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PubMed Mentions:
55 Fields:
Translation:
HumansCellsCTClinical Trials
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Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers. Phys Biol. 2012 Feb; 9(1):016003.
Marrinucci D, Bethel K, Kolatkar A, Luttgen MS, Malchiodi M, Baehring F, Voigt K, Lazar D, Nieva J, Bazhenova L, Ko AH, Korn WM, Schram E, Coward M, Yang X, Metzner T, Lamy R, Honnatti M, Yoshioka C, Kunken J, Petrova Y, Sok D, Nelson D, Kuhn P. PMID: 22306768; PMCID: PMC3387996.
View in:
PubMed Mentions:
144 Fields:
Translation:
HumansCells
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Fluid biopsy for circulating tumor cell identification in patients with early-and late-stage non-small cell lung cancer: a glimpse into lung cancer biology. Phys Biol. 2012 Feb; 9(1):016005.
Wendel M, Bazhenova L, Boshuizen R, Kolatkar A, Honnatti M, Cho EH, Marrinucci D, Sandhu A, Perricone A, Thistlethwaite P, Bethel K, Nieva J, Heuvel Mv, Kuhn P. PMID: 22307026; PMCID: PMC3387995.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansCellsCTClinical Trials
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Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature. 2011 Aug 31; 477(7362):99-102.
Breitbach CJ, Burke J, Jonker D, Stephenson J, Haas AR, Chow LQ, Nieva J, Hwang TH, Moon A, Patt R, Pelusio A, Le Boeuf F, Burns J, Evgin L, De Silva N, Cvancic S, Robertson T, Je JE, Lee YS, Parato K, Diallo JS, Fenster A, Daneshmand M, Bell JC, Kirn DH. PMID: 21886163.
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259 Fields:
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HumansCellsCTClinical Trials
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Cholesterol secosterol aldehydes induce amyloidogenesis and dysfunction of wild-type tumor protein p53. Chem Biol. 2011 Jul 29; 18(7):920-7.
Nieva J, Song BD, Rogel JK, Kujawara D, Altobel L, Izharrudin A, Boldt GE, Grover RK, Wentworth AD, Wentworth P. PMID: 21802012; PMCID: PMC3148486.
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12 Fields:
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HumansCells
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Cytomorphology of circulating colorectal tumor cells:a small case series. J Oncol. 2010; 2010:861341.
Marrinucci D, Bethel K, Lazar D, Fisher J, Huynh E, Clark P, Bruce R, Nieva J, Kuhn P. PMID: 20111743; PMCID: PMC2810476.
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58
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Circulating tumor cells from well-differentiated lung adenocarcinoma retain cytomorphologic features of primary tumor type. Arch Pathol Lab Med. 2009 Sep; 133(9):1468-71.
Marrinucci D, Bethel K, Luttgen M, Bruce RH, Nieva J, Kuhn P. PMID: 19722757; PMCID: PMC4422331.
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41 Fields:
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HumansCells
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The ratio of cholesterol 5,6-secosterols formed from ozone and singlet oxygen offers insight into the oxidation of cholesterol in vivo. Chem Commun (Camb). 2009 Jun 07; (21):3098-100.
Wentworth AD, Song BD, Nieva J, Shafton A, Tripurenani S, Wentworth P. PMID: 19462099; PMCID: PMC2819220.
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11 Fields:
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HumansCells
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Purification and characterization of sideroblasts from patients with acquired and hereditary sideroblastic anaemia. Br J Haematol. 2008 Nov; 143(3):446-50.
Martin FM, Prchal J, Nieva J, Saven A, Andrey J, Bethel K, Barton JC, Aripally G, Bottomley SS, Friedman JS. PMID: 18729851; PMCID: PMC2603068.
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2 Fields:
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HumansCells
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Lipid-derived aldehydes accelerate light chain amyloid and amorphous aggregation. Biochemistry. 2008 Jul 22; 47(29):7695-705.
Nieva J, Shafton A, Altobell LJ, Tripuraneni S, Rogel JK, Wentworth AD, Lerner RA, Wentworth P. PMID: 18578541.
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17 Fields:
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HumansCells
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Tissue factor activity is increased in a combined platelet and microparticle sample from cancer patients. Thromb Res. 2008; 122(5):604-9.
Tilley RE, Holscher T, Belani R, Nieva J, Mackman N. PMID: 18262600; PMCID: PMC2572216.
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31 Fields:
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HumansCells
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Understanding hairy cell leukemia genetics. Leuk Lymphoma. 2007 Apr; 48(4):653-4.
Nieva J, Saven A. PMID: 17454620.
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1 Fields:
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Humans
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The clinical significance of circulating tissue factor in prostate cancer. Thromb Haemost. 2007 Mar; 97(3):329-30.
Nieva J. PMID: 17334495.
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Humans
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Case study of the morphologic variation of circulating tumor cells. Hum Pathol. 2007 Mar; 38(3):514-9.
Marrinucci D, Bethel K, Bruce RH, Curry DN, Hsieh B, Humphrey M, Krivacic RT, Kroener J, Kroener L, Ladanyi A, Lazarus NH, Nieva J, Kuhn P. PMID: 17188328.
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71 Fields:
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HumansCells
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AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. N Engl J Med. 2006 Oct 19; 355(16):1672-81.
Bussel JB, Kuter DJ, George JN, McMillan R, Aledort LM, Conklin GT, Lichtin AE, Lyons RM, Nieva J, Wasser JS, Wiznitzer I, Kelly R, Chen CF, Nichol JL. PMID: 17050891.
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PubMed Mentions:
108 Fields:
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HumansCTClinical Trials
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Use of optophoresis as an in vitro predictor of cell response to chemotherapy for chronic lymphocytic leukemia. Leuk Lymphoma. 2006 Oct; 47(10):2194-202.
Nerenberg M, Kariv I, McNeeley P, Marchand P, Sur S, Diver J, Riccitelli S, Nieva J, Saven A. PMID: 17071495.
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3 Fields:
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HumansCells
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Proatherogenic effects of the cholesterol ozonolysis products, atheronal-A and atheronal-B. Biochemistry. 2006 Jun 13; 45(23):7162-70.
Takeuchi C, Galvé R, Nieva J, Witter DP, Wentworth AD, Troseth RP, Lerner RA, Wentworth P. PMID: 16752907.
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6 Fields:
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HumansAnimalsCells
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Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization. Nat Chem Biol. 2006 May; 2(5):249-53.
Bosco DA, Fowler DM, Zhang Q, Nieva J, Powers ET, Wentworth P, Lerner RA, Kelly JW. PMID: 16565714.
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133 Fields:
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HumansCells
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High speed detection of circulating tumor cells. Biosens Bioelectron. 2006 Apr 15; 21(10):1893-9.
Hsieh HB, Marrinucci D, Bethel K, Curry DN, Humphrey M, Krivacic RT, Kroener J, Kroener L, Ladanyi A, Lazarus N, Kuhn P, Bruce RH, Nieva J. PMID: 16464570.
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62 Fields:
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HumansCells
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Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway. Immunol Lett. 2006 Feb 28; 103(1):33-8.
Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P. PMID: 16386801.
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7 Fields:
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AnimalsCells
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SHP1 expression in bone marrow biopsies of myelodysplastic syndrome patients: a new prognostic factor. Br J Haematol. 2005 Jun; 129(6):791-4.
Mena-Duran AV, Togo SH, Bazhenova L, Cervera J, Bethel K, Senent ML, Nieva J, Sanz GF, Sanz MA, Saven A, Mustelin T. PMID: 15953006.
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7 Fields:
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Humans
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The antibody-catalyzed water oxidation pathway--a new chemical arm to immune defense? Trends Biochem Sci. 2004 May; 29(5):274-8.
Nieva J, Wentworth P. PMID: 15130564.
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13 Fields:
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HumansAnimalsCells
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Metabolite-initiated protein misfolding may trigger Alzheimer's disease. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):4752-7.
Zhang Q, Powers ET, Nieva J, Huff ME, Dendle MA, Bieschke J, Glabe CG, Eschenmoser A, Wentworth P, Lerner RA, Kelly JW. PMID: 15034169; PMCID: PMC387320.
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58 Fields:
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HumansCells
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Cladribine activity in systemic mast cell disease: application of biochemistry in the modern era of molecular biology. Leuk Res. 2004 Feb; 28(2):113-4.
Nieva J, Saven A. PMID: 14654073.
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HumansCells
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Evidence for ozone formation in human atherosclerotic arteries. Science. 2003 Nov 07; 302(5647):1053-6.
Wentworth P, Nieva J, Takeuchi C, Galve R, Wentworth AD, Dilley RB, DeLaria GA, Saven A, Babior BM, Janda KD, Eschenmoser A, Lerner RA. PMID: 14605372.
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54 Fields:
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HumansCells
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Phase 2 study of rituximab in the treatment of cladribine-failed patients with hairy cell leukemia. Blood. 2003 Aug 01; 102(3):810-3.
Nieva J, Bethel K, Saven A. PMID: 12663446.
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35 Fields:
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HumansCellsCTClinical Trials
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Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science. 2002 Dec 13; 298(5601):2195-9.
Wentworth P, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. PMID: 12434011.
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66 Fields:
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HumansAnimalsCells
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Injuries in youth ice hockey: a pilot surveillance strategy. Mayo Clin Proc. 1995 Apr; 70(4):350-6.
Stuart MJ, Smith AM, Nieva JJ, Rock MG. PMID: 7898141.
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PubMed Mentions:
10 Fields:
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HumansPHPublic Health