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Yang Chai, DMD, PhD, DDS

Title(s)Professor and Associate Dean, Research and Director, Center for Craniofacial Molecular Biology
AddressCSA 148
Health Sciences Campus
Los Angeles CA 90089-9062
Phone+1 323 442 3480
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    Collapse Biography 
    Collapse Awards and Honors
    NIDCR, NIH2013Chair of the Board of Scientific Counselors
    Craniofacial Biology Research Award2011IADR Distinguished Scientist Award
    Journal of Bone and Mineral Research2010  - 2014Editorial Board
    NIH2010 NIH MERIT Award
    2010American Association for the Advancement of Sciences (AAAS) Elected Fellow
    NIDCR, NIH2008  - 2012Member of the Board of Scientific Counselors
    JBMR2007  - 2014Editorial Board DEVELOPMENTAL BIOLOGY
    The Chinese Journal of Dental Research2006  - 2014Editorial Board
    2004  - 2008Regular member of SBDD study section CSR NIH
    2004Chair, Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration
    2006Chair, Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration
    2002  - 2014NIH Ad hoc grant reviewer (OBM-2, ODCS) and Reviewer for the Welcome Trust, UK
    University of Southern California2001  - 2003Award of Excellence in Teaching
    University of Southern California1997James H. Zumberge Faculty Research and Innovation Award
    University of Southern California2007James H. Zumberge Faculty Research and Innovation Award
    University of Southern California1997Annual Excellence in Teaching Award
    1996OKU Scholarship award for outstanding academic performance
    1996Special Recognition by the Dean for outstanding service and contribution to the University of Southe
    University of Southern California, School of Dentistry1995Annual Teaching Award
    University of Southern California, (GPA 4.0)1991PHI KAPPA PHI, All-University Honor Society
    University of Southern California1990Certificate for Outstanding Academic Achievement

    Collapse Overview 
    Collapse Overview
    Yang Chai, DMD, PhD, DDS is the chair of the National Institute of Dental and Craniofacial Research Board of Scientific Counselors.

    Professor Chai, who holds the George and Mary Lou Boone Chair in Craniofacial Biology and is the associate dean of research and director of the Center for Craniofacial Molecular Biology at the Ostrow School, has been a member of the board since 2008 and will serve a one-year term as chair. A total of nine board members, including the chair, are selected from among the most accomplished and celebrated experts in biomedical, dental and craniofacial science.

    Chai is internationally renowned for his research into the genetics, cellular signaling, and development of cranial and facial structures, including the causes of and potential preventive measures for facial deformities such as cleft palate. Among his many honors, he has received a National Institutes of Health MERIT Award, has been elected as an American Association for the Advancement of Sciences Fellow, has received an International Association for Dental Research Distinguished Scientist Award, and has served on the editorial boards of several scientific journals. He is also an alumnus of the Ostrow School of Dentistry and is an award-winning educator and a practicing dentist at the school.

    Collapse Research 
    Collapse Research Activities and Funding
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH/NIDCR U24DE029463May 7, 2020 - Apr 30, 2025
    Role: Principal Investigator
    USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration Hub
    NIH/NIDCR U01DE028729Aug 1, 2019 - Jul 31, 2024
    Role: Co-Principal Investigator
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH/NIDCR U24DE026914Mar 1, 2017 - Feb 29, 2020
    Role: Co-Principal Investigator
    Molecular and Cellular Basis of Craniosynostosis
    NIH/NIDCR R01DE026339Jul 1, 2016 - Mar 31, 2021
    Role: Co-Principal Investigator
    MOLECULAR REGULATORY MECHANISM OF MESENCHYMAL STEM CELLS IN ADULT MOUSE INCISORS
    NIH/NIDCR R01DE025221May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    CENTER FOR DENTAL, ORAL AND CRANIOFACIAL TISSUE ORGAN REGENERATION (C-DOCTOR)
    NIH/NIDCR R34DE025575Sep 1, 2015 - Aug 31, 2016
    Role: Principal Investigator
    INTEGRATED RESEARCH OF FUNCTIONAL GENOMICS AND CRANIOFACIAL MORPHOGENESIS
    NIH/NIDCR U01DE024421May 12, 2014 - Apr 30, 2019
    Role: Principal Investigator
    THE MOLECULAR REGULATORY MECHANISM OF TOOTH ROOT DEVELOPMENT
    NIH/NIDCR R01DE022503Jul 19, 2012 - Jun 30, 2017
    Role: Principal Investigator
    RESEARCH ON FUNCTIONAL GENOMICS, IMAGE ANALYSIS AND RESCUE OF CLEFT PALATE
    NIH/NIDCR U01DE020065Sep 21, 2009 - Apr 30, 2014
    Role: Principal Investigator
    Interdisciplinary New Faculty Recruitment in Craniofacial Development
    NIH/NIDCR P30DE020750Sep 17, 2009 - Aug 31, 2013
    Role: Principal Investigator
    Molecular Regulatory Mechanism of Calvarial Morphogenesis
    NIH/NIDCR R01DE017007Sep 1, 2005 - Aug 31, 2012
    Role: Principal Investigator
    CRANIOFACIAL MORHOGENESIS AND TISSUE REGENERATION GORDON CONFERENCE
    NIH/NIDCR R13DE015783Jan 1, 2004 - Dec 31, 2008
    Role: Co-Principal Investigator
    MOLECULAR REGULATORY MECHANISM OF TONGUE MORPHOGENESIS
    NIH/NIDCR R01DE014078Apr 1, 2001 - Jun 30, 2014
    Role: Principal Investigator
    TGF BETA SIGNALING AND CRANIOFACIAL MORPHOGENESIS
    NIH/NIDCR R37DE012711Jan 1, 1999 - Nov 30, 2013
    Role: Principal Investigator
    TGF BETA SIGNALING AND CRANIOFACIAL MORPHOGENESIS
    NIH/NIDCR R01DE012711Jan 1, 1999 - Sep 24, 2009
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse In The News
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Novel Single-Enzyme Assisted Dual Recycle Amplification Strategy for Sensitive Photoelectrochemical MicroRNA Assay. Anal Chem. 2020 Sep 27. Xia L, Li M, Wang H, Yuan R, Chai YQ. PMID: 32985185.
      View in: PubMed   Mentions:    Fields:    
    2. FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research. Development. 2020 Sep 21; 147(18). Samuels BD, Aho R, Brinkley JF, Bugacov A, Feingold E, Fisher S, Gonzalez-Reiche AS, Hacia JG, Hallgrimsson B, Hansen K, Harris MP, Ho TV, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Leslie EJ, Li H, Liao EC, Long H, Lu N, Maas RL, Marazita ML, Mohammed J, Prescott S, Schuler R, Selleri L, Spritz RA, Swigut T, van Bakel H, Visel A, Welsh I, Williams C, Williams TJ, Wysocka J, Yuan Y, Chai Y. PMID: 32958507.
      View in: PubMed   Mentions:    Fields:    
    3. Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling. Cell Rep. 2020 Aug 11; 32(6):108007. Chen S, Jing J, Yuan Y, Feng J, Han X, Wen Q, Ho TV, Lee C, Chai Y. PMID: 32783935.
      View in: PubMed   Mentions:    Fields:    
    4. Gli1+ Periodontium Stem Cells Are Regulated by Osteocytes and Occlusal Force. Dev Cell. 2020 Sep 14; 54(5):639-654.e6. Men Y, Wang Y, Yi Y, Jing D, Luo W, Shen B, Stenberg W, Chai Y, Ge WP, Feng JQ, Zhao H. PMID: 32652075.
      View in: PubMed   Mentions: 1     Fields:    
    5. Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM. J Bone Miner Res. 2020 Jun 22. Wen Q, Jing J, Han X, Feng J, Yuan Y, Ma Y, Chen S, Ho TV, Chai Y. PMID: 32569388.
      View in: PubMed   Mentions:    Fields:    
    6. PRMT1-p53 Pathway Controls Epicardial EMT and Invasion. Cell Rep. 2020 Jun 09; 31(10):107739. Jackson-Weaver O, Ungvijanpunya N, Yuan Y, Qian J, Gou Y, Wu J, Shen H, Chen Y, Li M, Richard S, Chai Y, Sucov HM, Xu J. PMID: 32521264.
      View in: PubMed   Mentions: 1     Fields:    
    7. Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev. 2020 04 01; 34(7-8):580-597. Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF. PMID: 32115408.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. A Pre-clinical Animal Model of Secondary Head and Neck Lymphedema. Sci Rep. 2019 12 04; 9(1):18264. Daneshgaran G, Lo AY, Paik CB, Cooper MN, Sung C, Jiao W, Park SY, Ni P, Yu RP, Vorobyova I, Jashashvili T, Hong YK, Kim GH, Conti PS, Chai Y, Wong AK. PMID: 31797883.
      View in: PubMed   Mentions:    Fields:    
    9. Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019; 14(10):e0223879. Janecková E, Feng J, Li J, Rodriguez G, Chai Y. PMID: 31613912.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    10. Stretchable elastic synaptic transistors for neurologically integrated soft engineering systems. Sci Adv. 2019 10; 5(10):eaax4961. Shim H, Sim K, Ershad F, Yang P, Thukral A, Rao Z, Kim HJ, Liu Y, Wang X, Gu G, Gao L, Wang X, Chai Y, Yu C. PMID: 31646177.
      View in: PubMed   Mentions: 3     Fields:    
    11. A zirconium-based metal-organic framework sensitized by thioflavin-T for sensitive photoelectrochemical detection of C-reactive protein. Chem Commun (Camb). 2019 Sep 05; 55(72):10772-10775. Li MJ, Wang HJ, Yuan R, Chai YQ. PMID: 31432820.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. A novel "signal on" photoelectrochemical strategy based on dual functional hemin for microRNA assay. Chem Commun (Camb). 2019 Aug 21; 55(65):9721-9724. Xia LY, Li MJ, Wang HJ, Yuan R, Chai YQ. PMID: 31355383.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    13. Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars. Elife. 2019 07 01; 8. Jing J, Feng J, Li J, Han X, He J, Ho TV, Du J, Zhou X, Urata M, Chai Y. PMID: 31259687.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    14. p-n-Sensitized Heterostructure Co3O4/Fullerene with Highly Efficient Photoelectrochemical Performance for Ultrasensitive DNA Detection. ACS Appl Mater Interfaces. 2019 Jul 03; 11(26):23765-23772. Wang HH, Li MJ, Wang HJ, Chai YQ, Yuan R. PMID: 31252476.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation. Hum Mol Genet. 2019 05 15; 28(10):1726-1737. Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC. PMID: 30689861.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. [Ru(dcbpy)2 dppz]2+ /Fullerene Cosensitized PTB7-Th for Ultrasensitive Photoelectrochemical MicroRNA Assay. Chemistry. 2019 Mar 15; 25(16):4087-4092. Xia LY, Zheng YN, Liang WB, Li MJ, Hu T, Yuan R, Chai YQ. PMID: 30675925.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    17. Regulatory mechanisms of jaw bone and tooth development. Curr Top Dev Biol. 2019; 133:91-118. Yuan Y, Chai Y. PMID: 30902260.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    18. Discovering the forbidden Raman modes at the edges of layered materials. Sci Adv. 2018 Dec; 4(12):eaau6252. Guo Y, Zhang W, Wu H, Han J, Zhang Y, Lin S, Liu C, Xu K, Qiao J, Ji W, Chen Q, Gao S, Zhang W, Zhang X, Chai Y. PMID: 30555917.
      View in: PubMed   Mentions: 1     Fields:    
    19. BMP-IHH-mediated interplay between mesenchymal stem cells and osteoclasts supports calvarial bone homeostasis and repair. Bone Res. 2018; 6:30. Guo Y, Yuan Y, Wu L, Ho TV, Jing J, Sugii H, Li J, Han X, Feng J, Guo C, Chai Y. PMID: 30345151.
      View in: PubMed   Mentions:
    20. Process analysis of anaerobic fermentation of Phragmites australis straw and cow dung exposing to elevated chromium (VI) concentrations. J Environ Manage. 2018 Oct 15; 224:414-424. Zhang H, Han X, Tian Y, Li Y, Yang K, Hao H, Chai Y, Xu X. PMID: 30075309.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    21. Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor. Cell Stem Cell. 2018 Jul 05; 23(1):147. Zhao H, Feng J, Seidel K, Shi S, Klein O, Sharpe P, Chai Y. PMID: 29979989.
      View in: PubMed   Mentions: 3     Fields:    
    22. Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion. Dev Biol. 2018 09 01; 441(1):191-203. Li J, Yuan Y, He J, Feng J, Han X, Jing J, Ho TV, Xu J, Chai Y. PMID: 29981310.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    23. Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor. Cell Rep. 2018 06 05; 23(10):3102-3111. An Z, Akily B, Sabalic M, Zong G, Chai Y, Sharpe PT. PMID: 29874594.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    24. Modulation of the Reduction Potential of TiO2- x by Fluorination for Efficient and Selective CH4 Generation from CO2 Photoreduction. . 2018 06 13; 18(6):3384-3390. Xing M, Zhou Y, Dong C, Cai L, Zeng L, Shen B, Pan L, Dong C, Chai Y, Zhang J, Yin Y. PMID: 29701060.
      View in: PubMed   Mentions:
    25. Prmt1 regulates craniofacial bone formation upstream of Msx1. Mech Dev. 2018 08; 152:13-20. Gou Y, Li J, Wu J, Gupta R, Cho I, Ho TV, Chai Y, Merrill A, Wang J, Xu J. PMID: 29727702.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    26. A Highly Sensitive Photoelectrochemical Assay with Donor-Acceptor-Type Material as Photoactive Material and Polyaniline as Signal Enhancer. Anal Chem. 2018 05 15; 90(10):6096-6101. Hu T, Zheng YN, Li MJ, Liang WB, Chai YQ, Yuan R. PMID: 29676147.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    27. Enzyme-free Target Recycling and Double-Output Amplification System for Electrochemiluminescent Assay of Mucin 1 with MoS2 Nanoflowers as Co-reaction Accelerator. ACS Appl Mater Interfaces. 2018 May 02; 10(17):14483-14490. Li SK, Liu ZT, Li JY, Chen AY, Chai YQ, Yuan R, Zhuo Y. PMID: 29664278.
      View in: PubMed   Mentions:    Fields:    
    28. The role of Hedgehog-responsive fibroblasts in facial nerve regeneration. Exp Neurol. 2018 05; 303:72-79. Bobarnac Dogaru GL, Juneja SC, Shokrani A, Hui RY, Chai Y, Pepper JP. PMID: 29337143.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    29. Using p-type PbS Quantum Dots to Quench Photocurrent of Fullerene-Au NP@MoS2 Composite Structure for Ultrasensitive Photoelectrochemical Detection of ATP. ACS Appl Mater Interfaces. 2017 Dec 06; 9(48):42111-42120. Li MJ, Zheng YN, Liang WB, Yuan R, Chai YQ. PMID: 29111661.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    30. The Dlx5-FGF10 signaling cascade controls cranial neural crest and myoblast interaction during oropharyngeal patterning and development. Development. 2017 11 01; 144(21):4037-4045. Sugii H, Grimaldi A, Li J, Parada C, Vu-Ho T, Feng J, Jing J, Yuan Y, Guo Y, Maeda H, Chai Y. PMID: 28982687.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    31. Hemin as electrochemically regenerable co-reaction accelerator for construction of an ultrasensitive PTCA-based electrochemiluminescent aptasensor. Biosens Bioelectron. 2018 Feb 15; 100:490-496. Zeng WJ, Liao N, Lei YM, Zhao J, Chai YQ, Yuan R, Zhuo Y. PMID: 28965054.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    32. Ultrahigh mobility and efficient charge injection in monolayer organic thin-film transistors on boron nitride. Sci Adv. 2017 09; 3(9):e1701186. He D, Qiao J, Zhang L, Wang J, Lan T, Qian J, Li Y, Shi Y, Chai Y, Lan W, Ono LK, Qi Y, Xu JB, Ji W, Wang X. PMID: 28913429.
      View in: PubMed   Mentions: 7     Fields:    
    33. An efficient electrochemiluminescence amplification strategy via bis-co-reaction accelerator for sensitive detection of laminin to monitor overnutrition associated liver damage. Biosens Bioelectron. 2017 Dec 15; 98:317-324. Zhao J, Liang WB, Lei YM, Ou YX, Chai YQ, Yuan R, Zhuo Y. PMID: 28697444.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Topical Fibronectin Improves Wound Healing of Irradiated Skin. Sci Rep. 2017 06 20; 7(1):3876. Johnson MB, Pang B, Gardner DJ, Niknam-Benia S, Soundarajan V, Bramos A, Perrault DP, Banks K, Lee GK, Baker RY, Kim GH, Lee S, Chai Y, Chen M, Li W, Kwong L, Hong YK, Wong AK. PMID: 28634413.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsPHPublic Health
    35. Enhanced Photocatalytic Activity of WS2 Film by Laser Drilling to Produce Porous WS2/WO3 Heterostructure. Sci Rep. 2017 06 09; 7(1):3125. Ma S, Zeng L, Tao L, Tang CY, Yuan H, Long H, Cheng PK, Chai Y, Chen C, Fung KH, Zhang X, Lau SP, Tsang YH. PMID: 28600560.
      View in: PubMed   Mentions:    Fields:    
    36. BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice. Development. 2017 07 15; 144(14):2560-2569. Feng J, Jing J, Li J, Zhao H, Punj V, Zhang T, Xu J, Chai Y. PMID: 28576771.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    37. Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate. Hum Mol Genet. 2017 03 01; 26(5):860-872. Tian H, Feng J, Li J, Ho TV, Yuan Y, Liu Y, Brindopke F, Figueiredo JC, Magee W, Sanchez-Lara PA, Chai Y. PMID: 28069795.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    38. Cellular and molecular mechanisms of tooth root development. Development. 2017 02 01; 144(3):374-384. Li J, Parada C, Chai Y. PMID: 28143844.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    39. Nonstoichiometric acid-base reaction as reliable synthetic route to highly stable CH3NH3PbI3 perovskite film. Nat Commun. 2016 11 15; 7:13503. Long M, Zhang T, Chai Y, Ng CF, Mak TC, Xu J, Yan K. PMID: 27843140.
      View in: PubMed   Mentions: 5     Fields:    
    40. Sutures Possess Strong Regenerative Capacity for Calvarial Bone Injury. Stem Cells Dev. 2016 12 01; 25(23):1801-1807. Park S, Zhao H, Urata M, Chai Y. PMID: 27762665.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    41. Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development. 2016 11 15; 143(22):4115-4126. Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA. PMID: 27660324.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    42. Generation and characterization of tamoxifen-inducible Pax9-CreER knock-in mice using CrispR/Cas9. Genesis. 2016 09; 54(9):490-6. Feng J, Jing J, Sanchez-Lara PA, Bootwalla MS, Buckley J, Wu N, Yan Y, Chai Y. PMID: 27381449.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    43. Novel electrochemiluminescence of perylene derivative and its application to mercury ion detection based on a dual amplification strategy. Biosens Bioelectron. 2016 Dec 15; 86:720-727. Zhao J, Lei YM, Chai YQ, Yuan R, Zhuo Y. PMID: 27474970.
      View in: PubMed   Mentions: 2     Fields:    
    44. The FaceBase Consortium: a comprehensive resource for craniofacial researchers. Development. 2016 07 15; 143(14):2677-88. Brinkley JF, Fisher S, Harris MP, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Maas RL, Marazita ML, Selleri L, Spritz RA, van Bakel H, Visel A, Williams TJ, Wysocka J, Chai Y. PMID: 27287806.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    45. Epidemiology, Etiology, and Treatment of Isolated Cleft Palate. Front Physiol. 2016; 7:67. Burg ML, Chai Y, Yao CA, Magee W, Figueiredo JC. PMID: 26973535.
      View in: PubMed   Mentions:
    46. A Comprehensive Study of Soft Palate Development in Mice. PLoS One. 2015; 10(12):e0145018. Grimaldi A, Parada C, Chai Y. PMID: 26671681.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    47. Mandible and Tongue Development. Curr Top Dev Biol. 2015; 115:31-58. Parada C, Chai Y. PMID: 26589920.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    48. Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. Development. 2015 Nov 01; 142(21):3734-45. Parada C, Han D, Grimaldi A, Sarrión P, Park SS, Pelikan R, Sanchez-Lara PA, Chai Y. PMID: 26395480.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    49. An Nfic-hedgehog signaling cascade regulates tooth root development. Development. 2015 Oct 01; 142(19):3374-82. Liu Y, Feng J, Li J, Zhao H, Ho TV, Chai Y. PMID: 26293299.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    50. BMP-SHH signaling network controls epithelial stem cell fate via regulation of its niche in the developing tooth. Dev Cell. 2015 Apr 20; 33(2):125-35. Li J, Feng J, Liu Y, Ho TV, Grimes W, Ho HA, Park S, Wang S, Chai Y. PMID: 25865348.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    51. The suture provides a niche for mesenchymal stem cells of craniofacial bones. Nat Cell Biol. 2015 Apr; 17(4):386-96. Zhao H, Feng J, Ho TV, Grimes W, Urata M, Chai Y. PMID: 25799059.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    52. Temporo-spatial requirement of Smad4 in dentin formation. Biochem Biophys Res Commun. 2015 Apr 17; 459(4):706-12. Kim TH, Bae CH, Lee JY, Lee JC, Ko SO, Chai Y, Cho ES. PMID: 25770424.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    53. Integration of comprehensive 3D microCT and signaling analysis reveals differential regulatory mechanisms of craniofacial bone development. Dev Biol. 2015 Apr 15; 400(2):180-90. Ho TV, Iwata J, Ho HA, Grimes WC, Park S, Sanchez-Lara PA, Chai Y. PMID: 25722190.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    54. Enzyme-free electrochemical immunosensor based on host-guest nanonets catalyzing amplification for procalcitonin detection. ACS Appl Mater Interfaces. 2015 Feb 25; 7(7):4127-34. Shen WJ, Zhuo Y, Chai YQ, Yang ZH, Han J, Yuan R. PMID: 25629216.
      View in: PubMed   Mentions: 3     Fields:    
    55. New type of redox nanoprobe: C60-based nanomaterial and its application in electrochemical immunoassay for doping detection. Anal Chem. 2015 Feb 03; 87(3):1669-75. Han J, Zhuo Y, Chai YQ, Xiang Y, Yuan R. PMID: 25547661.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
    56. Preface. Curr Top Dev Biol. 2015; 115:xix-xxi. Chai Y. PMID: 26589940.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    57. A model for interprofessional health care: lessons learned from craniofacial teams. J Calif Dent Assoc. 2014 Sep; 42(9):637-44. Slavkin HC, Sanchez-Lara PA, Chai Y, Urata M. PMID: 25265730.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    58. ALK5-mediated transforming growth factor ß signaling in neural crest cells controls craniofacial muscle development via tissue-tissue interactions. Mol Cell Biol. 2014 Aug; 34(16):3120-31. Han A, Zhao H, Li J, Pelikan R, Chai Y. PMID: 24912677.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
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    137. Timing of odontogenic neural crest cell migration and tooth-forming capability in mice. Dev Dyn. 2003 Apr; 226(4):713-8. Zhang Y, Wang S, Song Y, Han J, Chai Y, Chen Y. PMID: 12666208.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    138. Prospects for tooth regeneration in the 21st century: a perspective. Microsc Res Tech. 2003 Apr 01; 60(5):469-79. Chai Y, Slavkin HC. PMID: 12619122.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    139. Developmental expression of Smad1-7 suggests critical function of TGF-beta/BMP signaling in regulating epithelial-mesenchymal interaction during tooth morphogenesis. Int J Dev Biol. 2003 Feb; 47(1):31-9. Xu X, Jeong L, Han J, Ito Y, Bringas P, Chai Y. PMID: 12653249.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    140. TGF-beta signaling and its functional significance in regulating the fate of cranial neural crest cells. Crit Rev Oral Biol Med. 2003; 14(2):78-88. Chai Y, Ito Y, Han J. PMID: 12764071.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    141. Developmental patterning of the circumvallate papilla. Int J Dev Biol. 2002 Aug; 46(5):755-63. Jitpukdeebodintra S, Chai Y, Snead ML. PMID: 12216988.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    142. Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development. Dev Dyn. 2002 May; 224(1):69-78. Ito Y, Bringas P, Mogharei A, Zhao J, Deng C, Chai Y. PMID: 11984875.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    143. Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice. Cells Tissues Organs. 2002; 170(2-3):83-98. Jaskoll T, Zhou YM, Chai Y, Makarenkova HP, Collinson JM, West JD, Hajihosseini MK, Lee J, Melnick M. PMID: 11731698.
      View in: PubMed   Mentions: 37     Fields:    Translation:Animals
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