Yang Chai, DMD, PhD, DDS

Title(s)University Professor and Associate Dean, Research and Director, Center for Craniofacial Molecular Biology
SchoolHerman Ostrow School of Dentistry of Usc
AddressCSA 148
Health Sciences Campus
Los Angeles CA 90089-9062
Phone+1 323 442 3480
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    Collapse Biography 
    Collapse Awards and Honors
    NIDCR, NIH2013Chair of the Board of Scientific Counselors
    Craniofacial Biology Research Award2011IADR Distinguished Scientist Award
    Journal of Bone and Mineral Research2010  - 2014Editorial Board
    NIH2010 NIH MERIT Award
    2010American Association for the Advancement of Sciences (AAAS) Elected Fellow
    NIDCR, NIH2008  - 2012Member of the Board of Scientific Counselors
    JBMR2007  - 2014Editorial Board DEVELOPMENTAL BIOLOGY
    The Chinese Journal of Dental Research2006  - 2014Editorial Board
    2004  - 2008Regular member of SBDD study section CSR NIH
    2004Chair, Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration
    2006Chair, Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration
    2002  - 2014NIH Ad hoc grant reviewer (OBM-2, ODCS) and Reviewer for the Welcome Trust, UK
    University of Southern California2001  - 2003Award of Excellence in Teaching
    University of Southern California1997James H. Zumberge Faculty Research and Innovation Award
    University of Southern California2007James H. Zumberge Faculty Research and Innovation Award
    University of Southern California1997Annual Excellence in Teaching Award
    1996OKU Scholarship award for outstanding academic performance
    1996Special Recognition by the Dean for outstanding service and contribution to the University of Southe
    University of Southern California, School of Dentistry1995Annual Teaching Award
    University of Southern California, (GPA 4.0)1991PHI KAPPA PHI, All-University Honor Society
    University of Southern California1990Certificate for Outstanding Academic Achievement

    Collapse Overview 
    Collapse Overview
    Yang Chai, DMD, PhD, DDS is the chair of the National Institute of Dental and Craniofacial Research Board of Scientific Counselors.

    Professor Chai, who holds the George and Mary Lou Boone Chair in Craniofacial Biology and is the associate dean of research and director of the Center for Craniofacial Molecular Biology at the Ostrow School, has been a member of the board since 2008 and will serve a one-year term as chair. A total of nine board members, including the chair, are selected from among the most accomplished and celebrated experts in biomedical, dental and craniofacial science.

    Chai is internationally renowned for his research into the genetics, cellular signaling, and development of cranial and facial structures, including the causes of and potential preventive measures for facial deformities such as cleft palate. Among his many honors, he has received a National Institutes of Health MERIT Award, has been elected as an American Association for the Advancement of Sciences Fellow, has received an International Association for Dental Research Distinguished Scientist Award, and has served on the editorial boards of several scientific journals. He is also an alumnus of the Ostrow School of Dentistry and is an award-winning educator and a practicing dentist at the school.

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms and rescue of craniosynostosis associated with gene-environment interaction
    NIH R01DE030901Jul 1, 2021 - Apr 30, 2026
    Role: Co-Principal Investigator
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH U24DE029463May 7, 2020 - Apr 30, 2025
    Role: Principal Investigator
    USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration Hub
    NIH U01DE028729Aug 1, 2019 - Jul 31, 2024
    Role: Co-Principal Investigator
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH U24DE026914Mar 1, 2017 - Feb 28, 2021
    Role: Co-Principal Investigator
    Molecular and Cellular Basis of Craniosynostosis
    NIH R01DE026339Jul 1, 2016 - Jul 31, 2026
    Role: Co-Principal Investigator
    NIH R01DE025221May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    NIH R34DE025575Sep 1, 2015 - Aug 31, 2017
    Role: Principal Investigator
    NIH U01DE024421May 12, 2014 - Apr 30, 2020
    Role: Principal Investigator
    NIH R01DE022503Jul 19, 2012 - Apr 30, 2024
    Role: Principal Investigator
    NIH U01DE020065Sep 21, 2009 - Apr 30, 2015
    Role: Principal Investigator
    Interdisciplinary New Faculty Recruitment in Craniofacial Development
    NIH P30DE020750Sep 17, 2009 - Aug 31, 2013
    Role: Principal Investigator
    Molecular Regulatory Mechanism of Calvarial Morphogenesis
    NIH R01DE017007Sep 1, 2005 - Aug 31, 2012
    Role: Principal Investigator
    NIH R13DE015783Jan 1, 2004 - Dec 31, 2008
    Role: Co-Principal Investigator
    NIH R01DE014078Apr 1, 2001 - Jun 30, 2015
    Role: Principal Investigator
    NIH R01DE012711Jan 1, 1999 - Jul 31, 2024
    Role: Principal Investigator
    NIH R37DE012711Jan 1, 1999 - Jul 31, 2019
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Electrochromic Devices Based on 2D MoO3-x/PEDOT:PSS Composite Film with Boosted Ion Transport. ACS Appl Mater Interfaces. 2024 Apr 10; 16(14):18052-18062. Yu H, Fang H, Jing K, Ma H, Wu L, Chai Y. PMID: 38546439.
      View in: PubMed   Mentions:    Fields:    
    2. Renewable Electrochemiluminescence Biosensor Based on Eu-MOGs as a Highly Efficient Emitter and a DNAzyme-Mediated Dual-drive DNA Walker as a Signal Amplifier for Ultrasensitive Detection of miRNA-222. Anal Chem. 2024 Mar 19; 96(11):4589-4596. Chen YF, Guo YZ, Xiao S, Chai YQ, Liu JL, Yuan R. PMID: 38442212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Polymerized carbon dots with high electrochemiluminescence efficiency and long wavelength ECL emission for ultrasensitive detection of MicroRNA-222. Biosens Bioelectron. 2024 Jun 15; 254:116193. Xiao S, Yang YT, Chen YF, Liu JL, Chai YQ, Yuan R. PMID: 38479342.
      View in: PubMed   Mentions:    Fields:    
    4. Elevated transaminases in congenital central hypoventilation syndrome. ERJ Open Res. 2024 Jan; 10(1). Wang RY, Wang VS, Keens TG, Chai Y, Soufi N, Perez IA. PMID: 38375431; PMCID: PMC10875468.
      View in: PubMed   Mentions:
    5. Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis. Development. 2024 Jan 15; 151(2). Pei F, Ma L, Guo T, Zhang M, Jing J, Wen Q, Feng J, Lei J, He J, Janecková E, Ho TV, Chen JF, Chai Y. PMID: 38108472; PMCID: PMC10820866.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Generation of tamoxifen-inducible Tfap2b-CreERT2 mice using CRISPR-Cas9. Genesis. 2023 Dec 08; e23582. Zhang M, Feng J, Li Y, Qin PZ, Chai Y. PMID: 38069547.
      View in: PubMed   Mentions:    Fields:    
    7. Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis. Cell Stem Cell. 2023 11 02; 30(11):1472-1485.e7. Ma L, Chang Q, Pei F, Liu M, Zhang W, Hong YK, Chai Y, Chen JF. PMID: 37863055; PMCID: PMC10842404.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    8. Factors affecting do-not-attempt-resuscitation (DNAR) decisions among adult patients in the emergency department of a general tertiary teaching hospital in China: a retrospective observational study. BMJ Open. 2023 10 10; 13(10):e075714. Wang CL, Liu Y, Gao YL, Li QS, Liu YC, Chai YF. PMID: 37816558; PMCID: PMC10565169.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Lineage-specific mutation of Lmx1b provides new insights into distinct regulation of suture development in different areas of the calvaria. Front Physiol. 2023; 14:1225118. Cabrera Pereira A, Dasgupta K, Ho TV, Pacheco-Vergara M, Kim J, Kataria N, Liang Y, Mei J, Yu J, Witek L, Chai Y, Jeong J. PMID: 37593235; PMCID: PMC10427921.
      View in: PubMed   Mentions:
    10. AgAuS Quantum Dots as a Highly Efficient Near-Infrared Electrochemiluminescence Emitter for the Ultrasensitive Detection of MicroRNA. Anal Chem. 2023 06 20; 95(24):9314-9322. Yang YT, Guo YZ, Shen ZC, Liu JL, Yuan R, Chai YQ. PMID: 37277958.
      View in: PubMed   Mentions: 1     Fields:    
    11. A Calvarial Defect Model to Investigate the Osteogenic Potential of Umbilical Cord Stem Cells in Bone Regeneration. Plast Reconstr Surg. 2024 Mar 01; 153(3):637-646. Stanton E, Feng J, Kondra K, Sanchez J, Jimenez C, Brown KS, Skiles ML, Urata MM, Chai Y, Hammoudeh JA. PMID: 37224290.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    12. A Biocompatible Supercapacitor Diode with Enhanced Rectification Capability toward Ion/Electron-Coupling Logic Operations. Adv Mater. 2023 Jun; 35(25):e2301218. Ma H, Liang J, Qiu J, Jiang L, Ma L, Sheng H, Shao M, Wang Q, Li F, Fu Y, Wang J, Xie E, Chai Y, Lan W. PMID: 36940232.
      View in: PubMed   Mentions: 1     Fields:    
    13. Nitrogen-, Sulfur-, and Fluorine-Codoped Carbon Dots with Low Excitation Potential and High Electrochemiluminescence Efficiency for Sensitive Detection of Matrix Metalloproteinase-2. Anal Chem. 2023 05 02; 95(17):7021-7029. Guo YZ, Yang YT, Chen YF, Liu JL, Chai YQ, Yuan R. PMID: 37081730.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. A Self-Rectifying Synaptic Memristor Array with Ultrahigh Weight Potentiation Linearity for a Self-Organizing-Map Neural Network. Nano Lett. 2023 Apr 26; 23(8):3107-3115. Zhang H, Jiang B, Cheng C, Huang B, Zhang H, Chen R, Xu J, Huang Y, Chen H, Pei W, Chai Y, Zhou F. PMID: 37042482.
      View in: PubMed   Mentions: 1     Fields:    
    15. Current Understanding of the Regulatory Mechanism of Tooth Root Development and Future Perspectives. J Calif Dent Assoc. 2023; 51(1). Black N, Chai Y. PMID: 37193003; PMCID: PMC10168653.
      View in: PubMed   Mentions: 1     Fields:    
    16. Zn2+-Induced Gold Cluster Aggregation Enhanced Electrochemiluminescence for Ultrasensitive Detection of MicroRNA-21. Anal Chem. 2023 04 04; 95(13):5568-5574. Shen ZC, Yang YT, Guo YZ, Chai YQ, Liu JL, Yuan R. PMID: 36946240.
      View in: PubMed   Mentions:    Fields:    
    17. Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis. Development. 2023 03 01; 150(5). Janecková E, Feng J, Guo T, Han X, Ghobadi A, Araujo-Villalba A, Rahman MS, Ziaei H, Ho TV, Pareek S, Alvarez J, Chai Y. PMID: 36825984; PMCID: PMC10108707.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. High-Efficiency 3D DNA Walker Immobilized by a DNA Tetrahedral Nanostructure for Fast and Ultrasensitive Electrochemical Detection of MiRNA. Anal Chem. 2023 02 28; 95(8):4077-4085. Zhang XL, Li SS, Liu YJ, Liu WW, Kong LQ, Chai YQ, Luo XL, Yuan R. PMID: 36787389.
      View in: PubMed   Mentions: 1     Fields:    
    19. Target-mediated self-assembly of DNA networks for sensitive detection and intracellular imaging of APE1 in living cells. Chem Sci. 2023 Mar 01; 14(9):2318-2324. Zhou XM, Zhuo Y, Yuan R, Chai YQ. PMID: 36873854; PMCID: PMC9977452.
      View in: PubMed   Mentions: 1  
    20. Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis. Nat Commun. 2023 01 20; 14(1):344. Pei F, Ma L, Jing J, Feng J, Yuan Y, Guo T, Han X, Ho TV, Lei J, He J, Zhang M, Chen JF, Chai Y. PMID: 36670126; PMCID: PMC9859800.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    21. TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. Elife. 2022 12 21; 11. Feng J, Han X, Yuan Y, Cho CK, Janecková E, Guo T, Pareek S, Rahman MS, Zheng B, Bi J, Jing J, Zhang M, Xu J, Ho TV, Chai Y. PMID: 36542062; PMCID: PMC9771365.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    22. Room-temperature valley transistors for low-power neuromorphic computing. Nat Commun. 2022 Dec 15; 13(1):7758. Chen J, Zhou Y, Yan J, Liu J, Xu L, Wang J, Wan T, He Y, Zhang W, Chai Y. PMID: 36522374.
      View in: PubMed   Mentions: 1     Fields:    
    23. From Bedside to Bench and Back: Advancing Our Understanding of the Pathophysiology of Cleft Palate and Implications for the Future. Cleft Palate Craniofac J. 2024 May; 61(5):759-773. Stanton E, Sheridan S, Urata M, Chai Y. PMID: 36457208.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    24. Programmable mismatch-fueled high-efficiency DNA signal amplifier. Chem Sci. 2022 Oct 19; 13(40):11926-11935. Zhang XL, Li SS, Liu WW, Kong LQ, Chai YQ, Yuan R. PMID: 36320909; PMCID: PMC9580486.
      View in: PubMed   Mentions:
    25. Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 08 16; 13(1):4803. Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y. PMID: 35974052; PMCID: PMC9381504.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    26. A 619-pixel machine vision enhancement chip based on two-dimensional semiconductors. Sci Adv. 2022 Aug 05; 8(31):eabn9328. Ma S, Wu T, Chen X, Wang Y, Ma J, Chen H, Riaud A, Wan J, Xu Z, Chen L, Ren J, Zhang DW, Zhou P, Chai Y, Bao W. PMID: 35921422; PMCID: PMC9348785.
      View in: PubMed   Mentions: 3     Fields:    
    27. Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts. Development. 2022 07 15; 149(14). Gu R, Zhang S, Saha SK, Ji Y, Reynolds K, McMahon M, Sun B, Islam M, Trainor PA, Chen Y, Xu Y, Chai Y, Burkart-Waco D, Zhou CJ. PMID: 35781558; PMCID: PMC9382898.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    28. Topological phase change transistors based on tellurium Weyl semiconductor. Sci Adv. 2022 Jun 10; 8(23):eabn3837. Chen J, Zhang T, Wang J, Xu L, Lin Z, Liu J, Wang C, Zhang N, Lau SP, Zhang W, Chhowalla M, Chai Y. PMID: 35687677; PMCID: PMC9187226.
      View in: PubMed   Mentions: 3     Fields:    
    29. Construction of Fast-Walking Tetrahedral DNA Walker with Four Arms for Sensitive Detection and Intracellular Imaging of Apurinic/Apyrimidinic Endonuclease 1. Anal Chem. 2022 06 21; 94(24):8732-8739. Zhou XM, Zhuo Y, Tu TT, Yuan R, Chai YQ. PMID: 35678832.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    30. Effect of sponsor on enrollment criteria in non-small cell lung cancer clinical trials. J Cancer Policy. 2022 09; 33:100336. Cooper RA, Chai Y, Nieva J. PMID: 35605888; PMCID: PMC10226152.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Boron and Nitrogen-Codoped Carbon Dots as Highly Efficient Electrochemiluminescence Emitters for Ultrasensitive Detection of Hepatitis B Virus DNA. Anal Chem. 2022 05 31; 94(21):7601-7608. Guo YZ, Liu JL, Chen YF, Chai YQ, Li ZH, Yuan R. PMID: 35575687.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    32. Scalable production of ultrafine polyaniline fibres for tactile organic electrochemical transistors. Nat Commun. 2022 Apr 19; 13(1):2101. Fang B, Yan J, Chang D, Piao J, Ma KM, Gu Q, Gao P, Chai Y, Tao X. PMID: 35440125; PMCID: PMC9018749.
      View in: PubMed   Mentions: 13     Fields:    
    33. The clinical manifestations, molecular mechanisms and treatment of craniosynostosis. Dis Model Mech. 2022 04 01; 15(4). Stanton E, Urata M, Chen JF, Chai Y. PMID: 35451466; PMCID: PMC9044212.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    34. KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. Elife. 2022 02 25; 11. Guo T, Han X, He J, Feng J, Jing J, Janecková E, Lei J, Ho TV, Xu J, Chai Y. PMID: 35212626; PMCID: PMC9007587.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    35. Embryonic requirements for Tcf12 in the development of the mouse coronal suture. Development. 2022 01 01; 149(1). Ting MC, Farmer DT, Teng CS, He J, Chai Y, Crump JG, Maxson RE. PMID: 34878091; PMCID: PMC8783042.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    36. Transferred metal gate to 2D semiconductors for sub-1 V operation and near ideal subthreshold slope. Sci Adv. 2021 Oct 29; 7(44):eabf8744. Wang J, Cai L, Chen J, Guo X, Liu Y, Ma Z, Xie Z, Huang H, Chan M, Zhu Y, Liao L, Shao Q, Chai Y. PMID: 34705513; PMCID: PMC8550226.
      View in: PubMed   Mentions: 2     Fields:    
    37. Mechanical Anisotropy in Two-Dimensional Selenium Atomic Layers. Nano Lett. 2021 10 13; 21(19):8043-8050. Qin JK, Sui C, Qin Z, Wu J, Guo H, Zhen L, Xu CY, Chai Y, Wang C, He X, Ye PD, Lou J. PMID: 34550704.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    38. DNA Structure-Stabilized Liquid-Liquid Self-Assembled Ordered Au Nanoparticle Interface for Sensitive Detection of MiRNA 155. Anal Chem. 2021 08 10; 93(31):11019-11024. Wu CJ, Huang SQ, Wang YY, Chai YQ, Yuan R, Yang X. PMID: 34324804.
      View in: PubMed   Mentions: 2     Fields:    
    39. Field-effect at electrical contacts to two-dimensional materials. Nano Res. 2021; 14(12):4894-4900. Guo Y, Sun Y, Tang A, Wang CH, Zhao Y, Bai M, Xu S, Xu Z, Tang T, Wang S, Qiu C, Xu K, Peng X, Han J, Pop E, Chai Y. PMID: 34336143; PMCID: PMC8316888.
      View in: PubMed   Mentions: 1  
    40. Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika virus. EMBO Rep. 2021 08 04; 22(8):e51978. Ma L, Wang J, Ge J, Wang Y, Zhang W, Du Y, Luo J, Li Y, Wang F, Fan G, Chen R, Yao B, Zhao Z, Guo ML, Kim WK, Chai Y, Chen JF. PMID: 34232545; PMCID: PMC8344882.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    41. Arid1a regulates cell cycle exit of transit-amplifying cells by inhibiting the Aurka-Cdk1 axis in mouse incisor. Development. 2021 04 15; 148(8). Du J, Jing J, Chen S, Yuan Y, Feng J, Ho TV, Sehgal P, Xu J, Jiang X, Chai Y. PMID: 33766930; PMCID: PMC8077510.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    42. Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors. Cell Rep. 2021 04 06; 35(1):108964. Du J, Jing J, Yuan Y, Feng J, Han X, Chen S, Li X, Peng W, Xu J, Ho TV, Jiang X, Chai Y. PMID: 33826897; PMCID: PMC8132592.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    43. Mesenchymal stem cells and three-dimensional-osteoconductive scaffold regenerate calvarial bone in critical size defects in swine. Stem Cells Transl Med. 2021 08; 10(8):1170-1183. Johnson ZM, Yuan Y, Li X, Jashashvili T, Jamieson M, Urata M, Chen Y, Chai Y. PMID: 33794062; PMCID: PMC8284781.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    44. Lhx6 regulates canonical Wnt signaling to control the fate of mesenchymal progenitor cells during mouse molar root patterning. PLoS Genet. 2021 02; 17(2):e1009320. He J, Jing J, Feng J, Han X, Yuan Y, Guo T, Pei F, Ma Y, Cho C, Ho TV, Chai Y. PMID: 33596195; PMCID: PMC7920342.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    45. Reciprocal interaction between mesenchymal stem cells and transit amplifying cells regulates tissue homeostasis. Elife. 2021 01 22; 10. Jing J, Feng J, Li J, Zhao H, Ho TV, He J, Yuan Y, Guo T, Du J, Urata M, Sharpe P, Chai Y. PMID: 33480845; PMCID: PMC7822593.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    46. Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis. Elife. 2021 01 22; 10. Han X, Feng J, Guo T, Loh YE, Yuan Y, Ho TV, Cho CK, Li J, Jing J, Janeckova E, He J, Pei F, Bi J, Song B, Chai Y. PMID: 33482080; PMCID: PMC7826157.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    47. Ror2-mediated non-canonical Wnt signaling regulates Cdc42 and cell proliferation during tooth root development. Development. 2021 01 21; 148(2). Ma Y, Jing J, Feng J, Yuan Y, Wen Q, Han X, He J, Chen S, Ho TV, Chai Y. PMID: 33323370; PMCID: PMC7847279.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    48. Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis. Cell. 2021 01 07; 184(1):243-256.e18. Yu M, Ma L, Yuan Y, Ye X, Montagne A, He J, Ho TV, Wu Y, Zhao Z, Sta Maria N, Jacobs R, Urata M, Wang H, Zlokovic BV, Chen JF, Chai Y. PMID: 33417861; PMCID: PMC7891303.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    49. Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis. Sci Adv. 2020 12; 6(51). Yuan Y, Loh YE, Han X, Feng J, Ho TV, He J, Jing J, Groff K, Wu A, Chai Y. PMID: 33328221; PMCID: PMC7744069.
      View in: PubMed   Mentions: 14     Fields:    
    50. FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research. Development. 2020 09 21; 147(18). Samuels BD, Aho R, Brinkley JF, Bugacov A, Feingold E, Fisher S, Gonzalez-Reiche AS, Hacia JG, Hallgrimsson B, Hansen K, Harris MP, Ho TV, Holmes G, Hooper JE, Jabs EW, Jones KL, Kesselman C, Klein OD, Leslie EJ, Li H, Liao EC, Long H, Lu N, Maas RL, Marazita ML, Mohammed J, Prescott S, Schuler R, Selleri L, Spritz RA, Swigut T, van Bakel H, Visel A, Welsh I, Williams C, Williams TJ, Wysocka J, Yuan Y, Chai Y. PMID: 32958507; PMCID: PMC7522026.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    51. Rational design of Al2O3/2D perovskite heterostructure dielectric for high performance MoS2 phototransistors. Nat Commun. 2020 Aug 26; 11(1):4266. Jiang J, Zou X, Lv Y, Liu Y, Xu W, Tao Q, Chai Y, Liao L. PMID: 32848133; PMCID: PMC7450060.
      View in: PubMed   Mentions: 5     Fields:    
    52. Lattice oxygen activation enabled by high-valence metal sites for enhanced water oxidation. Nat Commun. 2020 Aug 13; 11(1):4066. Zhang N, Feng X, Rao D, Deng X, Cai L, Qiu B, Long R, Xiong Y, Lu Y, Chai Y. PMID: 32792524; PMCID: PMC7426847.
      View in: PubMed   Mentions: 21     Fields:    
    53. Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling. Cell Rep. 2020 08 11; 32(6):108007. Chen S, Jing J, Yuan Y, Feng J, Han X, Wen Q, Ho TV, Lee C, Chai Y. PMID: 32783935; PMCID: PMC7461627.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    54. Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM. J Bone Miner Res. 2020 11; 35(11):2252-2264. Wen Q, Jing J, Han X, Feng J, Yuan Y, Ma Y, Chen S, Ho TV, Chai Y. PMID: 32569388; PMCID: PMC7689689.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    55. Gli1+ Periodontium Stem Cells Are Regulated by Osteocytes and Occlusal Force. Dev Cell. 2020 09 14; 54(5):639-654.e6. Men Y, Wang Y, Yi Y, Jing D, Luo W, Shen B, Stenberg W, Chai Y, Ge WP, Feng JQ, Zhao H. PMID: 32652075.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    56. PRMT1-p53 Pathway Controls Epicardial EMT and Invasion. Cell Rep. 2020 06 09; 31(10):107739. Jackson-Weaver O, Ungvijanpunya N, Yuan Y, Qian J, Gou Y, Wu J, Shen H, Chen Y, Li M, Richard S, Chai Y, Sucov HM, Xu J. PMID: 32521264; PMCID: PMC7425665.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
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    129. A TGFβ-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development. Development. 2012 May; 139(9):1640-50. Han D, Zhao H, Parada C, Hacia JG, Bringas P, Chai Y. PMID: 22438570; PMCID: PMC3317969.
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    130. Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice. J Clin Invest. 2012 Mar; 122(3):873-85. Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y. PMID: 22326956; PMCID: PMC3287237.
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    131. Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. J Biol Chem. 2012 Jan 20; 287(4):2353-63. Iwata J, Tung L, Urata M, Hacia JG, Pelikan R, Suzuki A, Ramenzoni L, Chaudhry O, Parada C, Sanchez-Lara PA, Chai Y. PMID: 22123828; PMCID: PMC3268397.
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    132. Novel electrochemical catalysis as signal amplified strategy for label-free detection of neuron-specific enolase. Biosens Bioelectron. 2012 Jan 15; 31(1):399-405. Han J, Zhuo Y, Chai YQ, Yuan YL, Yuan R. PMID: 22169815.
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    133. Molecular regulatory mechanism of root development. J Calif Dent Assoc. 2011 May; 39(5):321-4. Hung Y, Huang X, Chai Y. PMID: 21721476.
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    134. SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development. 2011 May; 138(10):1977-89. Li J, Huang X, Xu X, Mayo J, Bringas P, Jiang R, Wang S, Chai Y. PMID: 21490069; PMCID: PMC3082303.
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    135. Highly conducting gold nanoparticles-graphene nanohybrid films for ultrasensitive detection of carcinoembryonic antigen. Talanta. 2011 Jul 15; 85(1):130-5. Han J, Zhuo Y, Chai YQ, Mao L, Yuan YL, Yuan R. PMID: 21645681.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    136. The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol. 2011 Jul 15; 355(2):175-82. Hochheiser H, Aronow BJ, Artinger K, Beaty TH, Brinkley JF, Chai Y, Clouthier D, Cunningham ML, Dixon M, Donahue LR, Fraser SE, Hallgrimsson B, Iwata J, Klein O, Marazita ML, Murray JC, Murray S, de Villena FP, Postlethwait J, Potter S, Shapiro L, Spritz R, Visel A, Weinberg SM, Trainor PA. PMID: 21458441; PMCID: PMC3440302.
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    137. Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May; 31(10):2079-89. Zhao H, Li S, Han D, Kaartinen V, Chai Y. PMID: 21402782; PMCID: PMC3133354.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    138. Glucose oxidase and ferrocene labels immobilized at Au/TiO₂ nanocomposites with high load amount and activity for sensitive immunoelectrochemical measurement of ProGRP biomarker. Biosens Bioelectron. 2011 May 15; 26(9):3838-44. Zhuo Y, Chai YQ, Yuan R, Mao L, Yuan YL, Han J. PMID: 21429733.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    139. Msx1 and Dlx5 function synergistically to regulate frontal bone development. Genesis. 2010 Nov; 48(11):645-55. Chung IH, Han J, Iwata J, Chai Y. PMID: 20824629; PMCID: PMC2995851.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    140. Convergent genesis of an adult neural crest-like dermal stem cell from distinct developmental origins. Stem Cells. 2010 Nov; 28(11):2027-40. Jinno H, Morozova O, Jones KL, Biernaskie JA, Paris M, Hosokawa R, Rudnicki MA, Chai Y, Rossi F, Marra MA, Miller FD. PMID: 20848654; PMCID: PMC3087810.
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    141. Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis. Dev Biol. 2010 Nov 01; 347(1):109-21. He F, Xiong W, Wang Y, Matsui M, Yu X, Chai Y, Klingensmith J, Chen Y. PMID: 20727875; PMCID: PMC3010875.
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    142. Smad4-Shh-Nfic signaling cascade-mediated epithelial-mesenchymal interaction is crucial in regulating tooth root development. J Bone Miner Res. 2010 May; 25(5):1167-78. Huang X, Xu X, Bringas P, Hung YP, Chai Y. PMID: 19888897; PMCID: PMC3153373.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    143. Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J Immunol. 2010 Apr 15; 184(8):4295-306. Lu L, Wang J, Zhang F, Chai Y, Brand D, Wang X, Horwitz DA, Shi W, Zheng SG. PMID: 20304828; PMCID: PMC3087811.
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    144. TGF-beta mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue-tissue interactions during tongue morphogenesis. Dev Biol. 2010 May 01; 341(1):186-95. Hosokawa R, Oka K, Yamaza T, Iwata J, Urata M, Xu X, Bringas P, Nonaka K, Chai Y. PMID: 20193675; PMCID: PMC3336866.
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    145. Towards a molecular understanding of cleft palate. Beijing Da Xue Xue Bao Yi Xue Ban. 2010 Feb 18; 42(1):9-13. Chai Y. PMID: 20429146.
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    146. TGF-ß signalling and tooth development. Chin J Dent Res. 2010; 13(1):7-15. Huang XF, Chai Y. PMID: 20936186.
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    147. Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells. J Biol Chem. 2010 Feb 12; 285(7):4975-82. Iwata J, Hosokawa R, Sanchez-Lara PA, Urata M, Slavkin H, Chai Y. PMID: 19959467; PMCID: PMC2836101.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    148. Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice. Development. 2009 Dec; 136(24):4225-33. Han J, Mayo J, Xu X, Li J, Bringas P, Maas RL, Rubenstein JL, Chai Y. PMID: 19934017; PMCID: PMC2781056.
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    149. A highly selective polymeric membrane barium(II) electrode based on a macrocyclic tetrabasic ligand as neutral carrier. Anal Bioanal Chem. 2009 Oct; 395(3):855-62. Ma YH, Yuan R, Chai YQ, Liu XL. PMID: 19690838.
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    150. Fate of HERS during tooth root development. Dev Biol. 2009 Oct 01; 334(1):22-30. Huang X, Bringas P, Slavkin HC, Chai Y. PMID: 19576204; PMCID: PMC2744848.
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    151. Epithelial-specific requirement of FGFR2 signaling during tooth and palate development. J Exp Zool B Mol Dev Evol. 2009 Jun 15; 312B(4):343-50. Hosokawa R, Deng X, Takamori K, Xu X, Urata M, Bringas P, Chai Y. PMID: 19235875; PMCID: PMC2896559.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    152. Molecular characterization of a rice mutator-phenotype derived from an incompatible cross-pollination reveals transgenerational mobilization of multiple transposable elements and extensive epigenetic instability. BMC Plant Biol. 2009 May 29; 9:63. Wang H, Chai Y, Chu X, Zhao Y, Wu Y, Zhao J, Ngezahayo F, Xu C, Liu B. PMID: 19476655; PMCID: PMC2696445.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    153. Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner. PLoS One. 2009; 4(5):e5438. Noh T, Gabet Y, Cogan J, Shi Y, Tank A, Sasaki T, Criswell B, Dixon A, Lee C, Tam J, Kohler T, Segev E, Kockeritz L, Woodgett J, Müller R, Chai Y, Smith E, Bab I, Frenkel B. PMID: 19412553; PMCID: PMC2673053.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    154. Stem cell property of postmigratory cranial neural crest cells and their utility in alveolar bone regeneration and tooth development. Stem Cells. 2009 Apr; 27(4):866-77. Chung IH, Yamaza T, Zhao H, Choung PH, Shi S, Chai Y. PMID: 19350689; PMCID: PMC2896558.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    155. Emerging opportunities for the next generation of dental implants? Dent Today. 2009 Mar; 28(3):98-9. Shi S, Chai Y, Slavkin H. PMID: 19323323.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    156. Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science. 2009 Feb 27; 323(5918):1232-4. Zhang Z, Lan Y, Chai Y, Jiang R. PMID: 19251632; PMCID: PMC2650836.
      View in: PubMed   Mentions: 59     Fields:    Translation:Animals
    157. Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development. Dev Cell. 2008 Aug; 15(2):322-9. Xu X, Han J, Ito Y, Bringas P, Deng C, Chai Y. PMID: 18694570; PMCID: PMC2610417.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    158. Fabrication of an iodide-selective electrode based on phthalocyaninatotitanium(IV) oxide and the selective determination of iodide in actual samples. Anal Bioanal Chem. 2008 Sep; 392(1-2):297-303. Xu WJ, Yuan R, Chai YQ, Zhang TT, Liang WB, Wu X. PMID: 18622753.
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    159. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008 Aug 22; 283(34):23139-49. Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, Suzuki H, Aizawa S, Arakaki M, Yuasa K, Oka K, Chai Y, Nonaka K, Fukumoto S. PMID: 18559345.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    160. The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary. Dev Dyn. 2008 Jun; 237(6):1604-13. Anthwal N, Chai Y, Tucker AS. PMID: 18498113.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    161. Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten. Dev Biol. 2008 Aug 15; 320(2):340-50. Xing Y, Li C, Hu L, Tiozzo C, Li M, Chai Y, Bellusci S, Anderson S, Minoo P. PMID: 18602626; PMCID: PMC2597224.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    162. TGF-beta mediated Dlx5 signaling plays a crucial role in osteo-chondroprogenitor cell lineage determination during mandible development. Dev Biol. 2008 Sep 15; 321(2):303-9. Oka K, Oka S, Hosokawa R, Bringas P, Brockhoff HC, Nonaka K, Chai Y. PMID: 18684439; PMCID: PMC3378386.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    163. TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 01; 320(1):19-29. Zhao H, Oka K, Bringas P, Kaartinen V, Chai Y. PMID: 18572160; PMCID: PMC3629921.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    164. Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS One. 2008 Jan 30; 3(1):e1516. De Langhe SP, Carraro G, Tefft D, Li C, Xu X, Chai Y, Minoo P, Hajihosseini MK, Drouin J, Kaartinen V, Bellusci S. PMID: 18231602; PMCID: PMC2211394.
      View in: PubMed   Mentions: 77     Fields:    Translation:AnimalsCells
    165. TGF-beta signaling and aplasia cutis congenita: proposed animal model. J Calif Dent Assoc. 2007 Dec; 35(12):865-9. Zehnaly A, Hosokawa R, Urata M, Chai Y. PMID: 18240750.
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    166. Smad4 is required to regulate the fate of cranial neural crest cells. Dev Biol. 2007 Dec 01; 312(1):435-47. Ko SO, Chung IH, Xu X, Oka S, Zhao H, Cho ES, Deng C, Chai Y. PMID: 17964566; PMCID: PMC2704603.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    167. TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development. Dev Biol. 2007 Oct 01; 310(1):140-53. Hosokawa R, Urata M, Han J, Zehnaly A, Bringas P, Nonaka K, Chai Y. PMID: 17727833; PMCID: PMC3337706.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    168. Identification of novel genes expressed during mouse tooth development by microarray gene expression analysis. Dev Dyn. 2007 Aug; 236(8):2245-57. Pemberton TJ, Li FY, Oka S, Mendoza-Fandino GA, Hsu YH, Bringas P, Chai Y, Snead ML, Mehrian-Shai R, Patel PI. PMID: 17626284; PMCID: PMC4457363.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    169. Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development. Mech Dev. 2007 Sep-Oct; 124(9-10):729-45. Han J, Ishii M, Bringas P, Maas RL, Maxson RE, Chai Y. PMID: 17693062; PMCID: PMC2220014.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    170. Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation. Mech Dev. 2007 Jul; 124(6):409-15. Oka S, Oka K, Xu X, Sasaki T, Bringas P, Chai Y. PMID: 17449229; PMCID: PMC2704601.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    171. Wnt3a regulates Lef-1 expression during airway submucosal gland morphogenesis. Dev Biol. 2007 May 01; 305(1):90-102. Driskell RR, Goodheart M, Neff T, Liu X, Luo M, Moothart C, Sigmund CD, Hosokawa R, Chai Y, Engelhardt JF. PMID: 17335794; PMCID: PMC1892170.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    172. The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development. Dev Biol. 2007 Mar 01; 303(1):391-404. Oka K, Oka S, Sasaki T, Ito Y, Bringas P, Nonaka K, Chai Y. PMID: 17204263; PMCID: PMC2074881.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    173. Recent advances in craniofacial morphogenesis. Dev Dyn. 2006 Sep; 235(9):2353-75. Chai Y, Maxson RE. PMID: 16680722.
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    174. Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol. 2006 Aug 15; 296(2):298-314. Dudas M, Kim J, Li WY, Nagy A, Larsson J, Karlsson S, Chai Y, Kaartinen V. PMID: 16806156; PMCID: PMC1557652.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    175. Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion. Dev Biol. 2006 Sep 01; 297(1):238-48. Xu X, Han J, Ito Y, Bringas P, Urata MM, Chai Y. PMID: 16780827.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    176. An in vitro model for characterizing the post-migratory cranial neural crest cells of the first branchial arch. Dev Dyn. 2006 May; 235(5):1433-40. Zhao H, Bringas P, Chai Y. PMID: 16245337; PMCID: PMC3337696.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    177. TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development. Development. 2006 Jan; 133(2):371-81. Sasaki T, Ito Y, Bringas P, Chou S, Urata MM, Slavkin H, Chai Y. PMID: 16368934.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    178. Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant mice. Dev Biol. 2006 Jan 15; 289(2):420-9. Choudhary B, Ito Y, Makita T, Sasaki T, Chai Y, Sucov HM. PMID: 16332365.
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    179. Functional significance of Smad2 in regulating basal keratinocyte migration during wound healing. J Invest Dermatol. 2005 Dec; 125(6):1302-9. Hosokawa R, Urata MM, Ito Y, Bringas P, Chai Y. PMID: 16354202.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    180. Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development. 2005 Nov; 132(22):4937-50. Ishii M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE. PMID: 16221730.
      View in: PubMed   Mentions: 91     Fields:    Translation:Animals
    181. Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity. Evol Dev. 2005 Sep-Oct; 7(5):440-57. Plikus MV, Zeichner-David M, Mayer JA, Reyna J, Bringas P, Thewissen JG, Snead ML, Chai Y, Chuong CM. PMID: 16174037; PMCID: PMC4386657.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    182. Overexpression of Smad2 in Tgf-beta3-null mutant mice rescues cleft palate. Dev Biol. 2005 Feb 01; 278(1):193-202. Cui XM, Shiomi N, Chen J, Saito T, Yamamoto T, Ito Y, Bringas P, Chai Y, Shuler CF. PMID: 15649471.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    183. LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol. 2005 Feb 01; 278(1):130-43. Sasaki T, Ito Y, Xu X, Han J, Bringas P, Maeda T, Slavkin HC, Grosschedl R, Chai Y. PMID: 15649466.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    184. PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Dev Dyn. 2005 Jan; 232(1):75-84. Xu X, Bringas P, Soriano P, Chai Y. PMID: 15543606.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    185. A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 2005 Jan; 3(1):e11. Jamora C, Lee P, Kocieniewski P, Azhar M, Hosokawa R, Chai Y, Fuchs E. PMID: 15630473; PMCID: PMC539061.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    186. Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development. 2003 Nov; 130(21):5269-80. Ito Y, Yeo JY, Chytil A, Han J, Bringas P, Nakajima A, Shuler CF, Moses HL, Chai Y. PMID: 12975342.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    187. Cranial neural crest-derived mesenchymal proliferation is regulated by Msx1-mediated p19(INK4d) expression during odontogenesis. Dev Biol. 2003 Sep 01; 261(1):183-96. Han J, Ito Y, Yeo JY, Sucov HM, Maas R, Chai Y. PMID: 12941628.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    188. TGF-beta3-dependent SMAD2 phosphorylation and inhibition of MEE proliferation during palatal fusion. Dev Dyn. 2003 Jul; 227(3):387-94. Cui XM, Chai Y, Chen J, Yamamoto T, Ito Y, Bringas P, Shuler CF. PMID: 12815624.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    189. Timing of odontogenic neural crest cell migration and tooth-forming capability in mice. Dev Dyn. 2003 Apr; 226(4):713-8. Zhang Y, Wang S, Song Y, Han J, Chai Y, Chen Y. PMID: 12666208.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    190. Prospects for tooth regeneration in the 21st century: a perspective. Microsc Res Tech. 2003 Apr 01; 60(5):469-79. Chai Y, Slavkin HC. PMID: 12619122.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    191. Developmental expression of Smad1-7 suggests critical function of TGF-beta/BMP signaling in regulating epithelial-mesenchymal interaction during tooth morphogenesis. Int J Dev Biol. 2003 Feb; 47(1):31-9. Xu X, Jeong L, Han J, Ito Y, Bringas P, Chai Y. PMID: 12653249.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    192. TGF-beta signaling and its functional significance in regulating the fate of cranial neural crest cells. Crit Rev Oral Biol Med. 2003; 14(2):78-88. Chai Y, Ito Y, Han J. PMID: 12764071.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    193. Developmental patterning of the circumvallate papilla. Int J Dev Biol. 2002 Aug; 46(5):755-63. Jitpukdeebodintra S, Chai Y, Snead ML. PMID: 12216988.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    194. Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development. Dev Dyn. 2002 May; 224(1):69-78. Ito Y, Bringas P, Mogharei A, Zhao J, Deng C, Chai Y. PMID: 11984875.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    195. Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice. Cells Tissues Organs. 2002; 170(2-3):83-98. Jaskoll T, Zhou YM, Chai Y, Makarenkova HP, Collinson JM, West JD, Hajihosseini MK, Lee J, Melnick M. PMID: 11731698.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
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