Yang Chai, DMD, PhD, DDS

Title(s)Interim Dean, USC Herman Ostrow School of Dentistry
SchoolHerman Ostrow School of Dentistry of Usc
AddressCSA 148
University Park Campus
Los Angeles CA 90089-9062
Phone+1 323 442 3480
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    Other Positions
    Title(s)Professor of Dentistry


    Collapse Biography 
    Collapse Awards and Honors
    NIDCR, NIH2013Chair of the Board of Scientific Counselors
    Craniofacial Biology Research Award2011IADR Distinguished Scientist Award
    Journal of Bone and Mineral Research2010  - 2014Editorial Board
    NIH2010 NIH MERIT Award
    2010American Association for the Advancement of Sciences (AAAS) Elected Fellow
    NIDCR, NIH2008  - 2012Member of the Board of Scientific Counselors
    JBMR2007  - 2014Editorial Board DEVELOPMENTAL BIOLOGY
    The Chinese Journal of Dental Research2006  - 2014Editorial Board
    2004  - 2008Regular member of SBDD study section CSR NIH
    2004Chair, Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration
    2006Chair, Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration
    2002  - 2014NIH Ad hoc grant reviewer (OBM-2, ODCS) and Reviewer for the Welcome Trust, UK
    University of Southern California2001  - 2003Award of Excellence in Teaching
    University of Southern California1997James H. Zumberge Faculty Research and Innovation Award
    University of Southern California2007James H. Zumberge Faculty Research and Innovation Award
    University of Southern California1997Annual Excellence in Teaching Award
    1996OKU Scholarship award for outstanding academic performance
    1996Special Recognition by the Dean for outstanding service and contribution to the University of Southe
    University of Southern California, School of Dentistry1995Annual Teaching Award
    University of Southern California, (GPA 4.0)1991PHI KAPPA PHI, All-University Honor Society
    University of Southern California1990Certificate for Outstanding Academic Achievement

    Collapse Overview 
    Collapse Overview
    Yang Chai, DMD, PhD, DDS is the chair of the National Institute of Dental and Craniofacial Research Board of Scientific Counselors.

    Professor Chai, who holds the George and Mary Lou Boone Chair in Craniofacial Biology and is the associate dean of research and director of the Center for Craniofacial Molecular Biology at the Ostrow School, has been a member of the board since 2008 and will serve a one-year term as chair. A total of nine board members, including the chair, are selected from among the most accomplished and celebrated experts in biomedical, dental and craniofacial science.

    Chai is internationally renowned for his research into the genetics, cellular signaling, and development of cranial and facial structures, including the causes of and potential preventive measures for facial deformities such as cleft palate. Among his many honors, he has received a National Institutes of Health MERIT Award, has been elected as an American Association for the Advancement of Sciences Fellow, has received an International Association for Dental Research Distinguished Scientist Award, and has served on the editorial boards of several scientific journals. He is also an alumnus of the Ostrow School of Dentistry and is an award-winning educator and a practicing dentist at the school.

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms and rescue of craniosynostosis associated with gene-environment interaction
    NIH R01DE030901Jul 1, 2021 - Apr 30, 2026
    Role: Co-Principal Investigator
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH U24DE029463May 7, 2020 - Apr 30, 2025
    Role: Principal Investigator
    USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration Hub
    NIH U01DE028729Aug 1, 2019 - Jul 31, 2024
    Role: Co-Principal Investigator
    Center for Dental, Oral, and Craniofacial Tissue and Organ Regeneration (C-DOCTOR)
    NIH U24DE026914Mar 1, 2017 - Feb 28, 2021
    Role: Co-Principal Investigator
    Molecular and Cellular Basis of Craniosynostosis
    NIH R01DE026339Jul 1, 2016 - Jul 31, 2026
    Role: Co-Principal Investigator
    MOLECULAR REGULATORY MECHANISM OF MESENCHYMAL STEM CELLS IN ADULT MOUSE INCISORS
    NIH R01DE025221May 1, 2016 - Apr 30, 2021
    Role: Principal Investigator
    CENTER FOR DENTAL, ORAL AND CRANIOFACIAL TISSUE ORGAN REGENERATION (C-DOCTOR)
    NIH R34DE025575Sep 1, 2015 - Aug 31, 2017
    Role: Principal Investigator
    INTEGRATED RESEARCH OF FUNCTIONAL GENOMICS AND CRANIOFACIAL MORPHOGENESIS
    NIH U01DE024421May 12, 2014 - Apr 30, 2020
    Role: Principal Investigator
    THE MOLECULAR REGULATORY MECHANISM OF TOOTH ROOT DEVELOPMENT
    NIH R01DE022503Jul 19, 2012 - Apr 30, 2024
    Role: Principal Investigator
    RESEARCH ON FUNCTIONAL GENOMICS, IMAGE ANALYSIS AND RESCUE OF CLEFT PALATE
    NIH U01DE020065Sep 21, 2009 - Apr 30, 2015
    Role: Principal Investigator
    Interdisciplinary New Faculty Recruitment in Craniofacial Development
    NIH P30DE020750Sep 17, 2009 - Aug 31, 2013
    Role: Principal Investigator
    Molecular Regulatory Mechanism of Calvarial Morphogenesis
    NIH R01DE017007Sep 1, 2005 - Aug 31, 2012
    Role: Principal Investigator
    CRANIOFACIAL MORHOGENESIS AND TISSUE REGENERATION GORDON CONFERENCE
    NIH R13DE015783Jan 1, 2004 - Dec 31, 2008
    Role: Co-Principal Investigator
    MOLECULAR REGULATORY MECHANISM OF TONGUE MORPHOGENESIS
    NIH R01DE014078Apr 1, 2001 - Jun 30, 2015
    Role: Principal Investigator
    TGF BETA SIGNALING AND CRANIOFACIAL MORPHOGENESIS
    NIH R01DE012711Jan 1, 1999 - Jul 31, 2024
    Role: Principal Investigator
    TGF BETA SIGNALING AND CRANIOFACIAL MORPHOGENESIS
    NIH R37DE012711Jan 1, 1999 - Jul 31, 2019
    Role: Principal Investigator

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The G protein-coupled receptor ADGRG6 maintains mouse growth plate homeostasis through IHH Signaling. J Bone Miner Res. 2024 Sep 05. Bian F, Hansen V, Feng HC, He J, Chen Y, Feng K, Ebrahimi B, Gray RS, Chai Y, Wu CL, Liu Z. PMID: 39236220.
      View in: PubMed   Mentions:
    2. Nanoconfined Silver Nanoclusters Combined with X-Shaped DNA Recognizer-Triggered Cascade Amplification for Electrochemiluminescence Detection of APE1. Anal Chem. 2024 07 16; 96(28):11383-11389. Chen QL, Zhou XM, Zhao ML, Chai YQ, Yuan R, Zhong X, Zhuo Y. PMID: 38946419.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development. Bone Res. 2024 Jun 24; 12(1):37. Pei F, Guo T, Zhang M, Ma L, Jing J, Feng J, Ho TV, Wen Q, Chai Y. PMID: 38910207; PMCID: PMC11194271.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Neural crest and periderm-specific requirements of Irf6 during neural tube and craniofacial development. bioRxiv. 2024 Jun 11. Carroll SH, Schafer S, Dalessandro E, Ho TV, Chai Y, Liao EC. PMID: 38915513; PMCID: PMC11195129.
      View in: PubMed   Mentions:
    5. H-151 attenuates lipopolysaccharide-induced acute kidney injury by inhibiting the STING-TBK1 pathway. Ren Fail. 2024 Dec; 46(2):2363591. Xia L, Jiang JH, Liu JY, Zhang TY, Dong YX, Liu QH, Chai YF, Liu YC, Shou ST. PMID: 38856314; PMCID: PMC11168233.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    6. Exploring caspase functions in mouse models. Apoptosis. 2024 Aug; 29(7-8):938-966. Svandova E, Vesela B, Janeckova E, Chai Y, Matalova E. PMID: 38824481; PMCID: PMC11263464.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    7. ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling. Nat Commun. 2024 May 30; 15(1):4614. Zhang M, Guo T, Pei F, Feng J, Jing J, Xu J, Yamada T, Ho TV, Du J, Sehgal P, Chai Y. PMID: 38816354; PMCID: PMC11139927.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. FasL impacts Tgfb signaling in osteoblastic cells. Cells Dev. 2024 Sep; 179:203929. Kratochvilova A, Knopfova L, Gregorkova J, Gruber R, Janeckova E, Chai Y, Matalova E. PMID: 38810946.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    9. Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor. Cell Stem Cell. 2024 Jun 06; 31(6):904-920.e6. Guo T, Pei F, Zhang M, Yamada T, Feng J, Jing J, Ho TV, Chai Y. PMID: 38703771; PMCID: PMC11162319.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    10. Single-Atom Iron Doped Carbon Dots with Highly Efficient Electrochemiluminescence for Ultrasensitive Detection of MicroRNAs. Anal Chem. 2024 05 14; 96(19):7516-7523. Liao YY, Guo YZ, Liu JL, Shen ZC, Chai YQ, Yuan R. PMID: 38691765.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Electrochromic Devices Based on 2D MoO3-x/PEDOT:PSS Composite Film with Boosted Ion Transport. ACS Appl Mater Interfaces. 2024 Apr 10; 16(14):18052-18062. Yu H, Fang H, Jing K, Ma H, Wu L, Chai Y. PMID: 38546439.
      View in: PubMed   Mentions: 1     Fields:    
    12. Renewable Electrochemiluminescence Biosensor Based on Eu-MOGs as a Highly Efficient Emitter and a DNAzyme-Mediated Dual-drive DNA Walker as a Signal Amplifier for Ultrasensitive Detection of miRNA-222. Anal Chem. 2024 03 19; 96(11):4589-4596. Chen YF, Guo YZ, Xiao S, Chai YQ, Liu JL, Yuan R. PMID: 38442212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Polymerized carbon dots with high electrochemiluminescence efficiency and long wavelength ECL emission for ultrasensitive detection of MicroRNA-222. Biosens Bioelectron. 2024 Jun 15; 254:116193. Xiao S, Yang YT, Chen YF, Liu JL, Chai YQ, Yuan R. PMID: 38479342.
      View in: PubMed   Mentions:    Fields:    
    14. Elevated transaminases in congenital central hypoventilation syndrome. ERJ Open Res. 2024 Jan; 10(1). Wang RY, Wang VS, Keens TG, Chai Y, Soufi N, Perez IA. PMID: 38375431; PMCID: PMC10875468.
      View in: PubMed   Mentions:
    15. Optoelectronic Synapses Based on MXene/Violet Phosphorus van der Waals Heterojunctions for Visual-Olfactory Crossmodal Perception. Nanomicro Lett. 2024 Feb 01; 16(1):104. Ma H, Fang H, Xie X, Liu Y, Tian H, Chai Y. PMID: 38300424; PMCID: PMC10834395.
      View in: PubMed   Mentions: 1  
    16. Sensory nerve regulates progenitor cells via FGF-SHH axis in tooth root morphogenesis. Development. 2024 Jan 15; 151(2). Pei F, Ma L, Guo T, Zhang M, Jing J, Wen Q, Feng J, Lei J, He J, Janecková E, Ho TV, Chen JF, Chai Y. PMID: 38108472; PMCID: PMC10820866.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    17. Generation of tamoxifen-inducible Tfap2b-CreERT2 mice using CRISPR-Cas9. Genesis. 2024 02; 62(1):e23582. Zhang M, Feng J, Li Y, Qin PZ, Chai Y. PMID: 38069547; PMCID: PMC11021159.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    18. Skull progenitor cell-driven meningeal lymphatic restoration improves neurocognitive functions in craniosynostosis. Cell Stem Cell. 2023 11 02; 30(11):1472-1485.e7. Ma L, Chang Q, Pei F, Liu M, Zhang W, Hong YK, Chai Y, Chen JF. PMID: 37863055; PMCID: PMC10842404.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    19. Factors affecting do-not-attempt-resuscitation (DNAR) decisions among adult patients in the emergency department of a general tertiary teaching hospital in China: a retrospective observational study. BMJ Open. 2023 10 10; 13(10):e075714. Wang CL, Liu Y, Gao YL, Li QS, Liu YC, Chai YF. PMID: 37816558; PMCID: PMC10565169.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Lineage-specific mutation of Lmx1b provides new insights into distinct regulation of suture development in different areas of the calvaria. Front Physiol. 2023; 14:1225118. Cabrera Pereira A, Dasgupta K, Ho TV, Pacheco-Vergara M, Kim J, Kataria N, Liang Y, Mei J, Yu J, Witek L, Chai Y, Jeong J. PMID: 37593235; PMCID: PMC10427921.
      View in: PubMed   Mentions:
    21. AgAuS Quantum Dots as a Highly Efficient Near-Infrared Electrochemiluminescence Emitter for the Ultrasensitive Detection of MicroRNA. Anal Chem. 2023 06 20; 95(24):9314-9322. Yang YT, Guo YZ, Shen ZC, Liu JL, Yuan R, Chai YQ. PMID: 37277958.
      View in: PubMed   Mentions: 1     Fields:    
    22. A Calvarial Defect Model to Investigate the Osteogenic Potential of Umbilical Cord Stem Cells in Bone Regeneration. Plast Reconstr Surg. 2024 Mar 01; 153(3):637-646. Stanton E, Feng J, Kondra K, Sanchez J, Jimenez C, Brown KS, Skiles ML, Urata MM, Chai Y, Hammoudeh JA. PMID: 37224290.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    23. A Biocompatible Supercapacitor Diode with Enhanced Rectification Capability toward Ion/Electron-Coupling Logic Operations. Adv Mater. 2023 Jun; 35(25):e2301218. Ma H, Liang J, Qiu J, Jiang L, Ma L, Sheng H, Shao M, Wang Q, Li F, Fu Y, Wang J, Xie E, Chai Y, Lan W. PMID: 36940232.
      View in: PubMed   Mentions: 1     Fields:    
    24. Nitrogen-, Sulfur-, and Fluorine-Codoped Carbon Dots with Low Excitation Potential and High Electrochemiluminescence Efficiency for Sensitive Detection of Matrix Metalloproteinase-2. Anal Chem. 2023 05 02; 95(17):7021-7029. Guo YZ, Yang YT, Chen YF, Liu JL, Chai YQ, Yuan R. PMID: 37081730.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. A Self-Rectifying Synaptic Memristor Array with Ultrahigh Weight Potentiation Linearity for a Self-Organizing-Map Neural Network. Nano Lett. 2023 Apr 26; 23(8):3107-3115. Zhang H, Jiang B, Cheng C, Huang B, Zhang H, Chen R, Xu J, Huang Y, Chen H, Pei W, Chai Y, Zhou F. PMID: 37042482.
      View in: PubMed   Mentions: 1     Fields:    
    26. Current Understanding of the Regulatory Mechanism of Tooth Root Development and Future Perspectives. J Calif Dent Assoc. 2023; 51(1). Black N, Chai Y. PMID: 37193003; PMCID: PMC10168653.
      View in: PubMed   Mentions: 1     Fields:    
    27. Zn2+-Induced Gold Cluster Aggregation Enhanced Electrochemiluminescence for Ultrasensitive Detection of MicroRNA-21. Anal Chem. 2023 04 04; 95(13):5568-5574. Shen ZC, Yang YT, Guo YZ, Chai YQ, Liu JL, Yuan R. PMID: 36946240.
      View in: PubMed   Mentions: 1     Fields:    
    28. Canonical Wnt signaling regulates soft palate development by mediating ciliary homeostasis. Development. 2023 03 01; 150(5). Janecková E, Feng J, Guo T, Han X, Ghobadi A, Araujo-Villalba A, Rahman MS, Ziaei H, Ho TV, Pareek S, Alvarez J, Chai Y. PMID: 36825984; PMCID: PMC10108707.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    29. High-Efficiency 3D DNA Walker Immobilized by a DNA Tetrahedral Nanostructure for Fast and Ultrasensitive Electrochemical Detection of MiRNA. Anal Chem. 2023 02 28; 95(8):4077-4085. Zhang XL, Li SS, Liu YJ, Liu WW, Kong LQ, Chai YQ, Luo XL, Yuan R. PMID: 36787389.
      View in: PubMed   Mentions: 1     Fields:    
    30. Target-mediated self-assembly of DNA networks for sensitive detection and intracellular imaging of APE1 in living cells. Chem Sci. 2023 Mar 01; 14(9):2318-2324. Zhou XM, Zhuo Y, Yuan R, Chai YQ. PMID: 36873854; PMCID: PMC9977452.
      View in: PubMed   Mentions: 2  
    31. Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis. Nat Commun. 2023 01 20; 14(1):344. Pei F, Ma L, Jing J, Feng J, Yuan Y, Guo T, Han X, Ho TV, Lei J, He J, Zhang M, Chen JF, Chai Y. PMID: 36670126; PMCID: PMC9859800.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    32. TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. Elife. 2022 12 21; 11. Feng J, Han X, Yuan Y, Cho CK, Janecková E, Guo T, Pareek S, Rahman MS, Zheng B, Bi J, Jing J, Zhang M, Xu J, Ho TV, Chai Y. PMID: 36542062; PMCID: PMC9771365.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    33. Room-temperature valley transistors for low-power neuromorphic computing. Nat Commun. 2022 12 15; 13(1):7758. Chen J, Zhou Y, Yan J, Liu J, Xu L, Wang J, Wan T, He Y, Zhang W, Chai Y. PMID: 36522374; PMCID: PMC9755139.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    34. From Bedside to Bench and Back: Advancing Our Understanding of the Pathophysiology of Cleft Palate and Implications for the Future. Cleft Palate Craniofac J. 2024 May; 61(5):759-773. Stanton E, Sheridan S, Urata M, Chai Y. PMID: 36457208.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    35. Programmable mismatch-fueled high-efficiency DNA signal amplifier. Chem Sci. 2022 Oct 19; 13(40):11926-11935. Zhang XL, Li SS, Liu WW, Kong LQ, Chai YQ, Yuan R. PMID: 36320909; PMCID: PMC9580486.
      View in: PubMed   Mentions:
    36. Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 08 16; 13(1):4803. Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y. PMID: 35974052; PMCID: PMC9381504.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    37. A 619-pixel machine vision enhancement chip based on two-dimensional semiconductors. Sci Adv. 2022 Aug 05; 8(31):eabn9328. Ma S, Wu T, Chen X, Wang Y, Ma J, Chen H, Riaud A, Wan J, Xu Z, Chen L, Ren J, Zhang DW, Zhou P, Chai Y, Bao W. PMID: 35921422; PMCID: PMC9348785.
      View in: PubMed   Mentions: 4     Fields:    
    38. Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts. Development. 2022 07 15; 149(14). Gu R, Zhang S, Saha SK, Ji Y, Reynolds K, McMahon M, Sun B, Islam M, Trainor PA, Chen Y, Xu Y, Chai Y, Burkart-Waco D, Zhou CJ. PMID: 35781558; PMCID: PMC9382898.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    39. Topological phase change transistors based on tellurium Weyl semiconductor. Sci Adv. 2022 Jun 10; 8(23):eabn3837. Chen J, Zhang T, Wang J, Xu L, Lin Z, Liu J, Wang C, Zhang N, Lau SP, Zhang W, Chhowalla M, Chai Y. PMID: 35687677; PMCID: PMC9187226.
      View in: PubMed   Mentions: 7     Fields:    
    40. Construction of Fast-Walking Tetrahedral DNA Walker with Four Arms for Sensitive Detection and Intracellular Imaging of Apurinic/Apyrimidinic Endonuclease 1. Anal Chem. 2022 06 21; 94(24):8732-8739. Zhou XM, Zhuo Y, Tu TT, Yuan R, Chai YQ. PMID: 35678832.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    41. Effect of sponsor on enrollment criteria in non-small cell lung cancer clinical trials. J Cancer Policy. 2022 09; 33:100336. Cooper RA, Chai Y, Nieva J. PMID: 35605888; PMCID: PMC10226152.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Boron and Nitrogen-Codoped Carbon Dots as Highly Efficient Electrochemiluminescence Emitters for Ultrasensitive Detection of Hepatitis B Virus DNA. Anal Chem. 2022 05 31; 94(21):7601-7608. Guo YZ, Liu JL, Chen YF, Chai YQ, Li ZH, Yuan R. PMID: 35575687.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    43. Scalable production of ultrafine polyaniline fibres for tactile organic electrochemical transistors. Nat Commun. 2022 Apr 19; 13(1):2101. Fang B, Yan J, Chang D, Piao J, Ma KM, Gu Q, Gao P, Chai Y, Tao X. PMID: 35440125; PMCID: PMC9018749.
      View in: PubMed   Mentions: 14     Fields:    
    44. The clinical manifestations, molecular mechanisms and treatment of craniosynostosis. Dis Model Mech. 2022 04 01; 15(4). Stanton E, Urata M, Chen JF, Chai Y. PMID: 35451466; PMCID: PMC9044212.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    45. KDM6B interacts with TFDP1 to activate P53 signaling in regulating mouse palatogenesis. Elife. 2022 02 25; 11. Guo T, Han X, He J, Feng J, Jing J, Janecková E, Lei J, Ho TV, Xu J, Chai Y. PMID: 35212626; PMCID: PMC9007587.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    46. Embryonic requirements for Tcf12 in the development of the mouse coronal suture. Development. 2022 01 01; 149(1). Ting MC, Farmer DT, Teng CS, He J, Chai Y, Crump JG, Maxson RE. PMID: 34878091; PMCID: PMC8783042.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    47. Transferred metal gate to 2D semiconductors for sub-1 V operation and near ideal subthreshold slope. Sci Adv. 2021 Oct 29; 7(44):eabf8744. Wang J, Cai L, Chen J, Guo X, Liu Y, Ma Z, Xie Z, Huang H, Chan M, Zhu Y, Liao L, Shao Q, Chai Y. PMID: 34705513; PMCID: PMC8550226.
      View in: PubMed   Mentions: 3     Fields:    
    48. Mechanical Anisotropy in Two-Dimensional Selenium Atomic Layers. Nano Lett. 2021 10 13; 21(19):8043-8050. Qin JK, Sui C, Qin Z, Wu J, Guo H, Zhen L, Xu CY, Chai Y, Wang C, He X, Ye PD, Lou J. PMID: 34550704.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. DNA Structure-Stabilized Liquid-Liquid Self-Assembled Ordered Au Nanoparticle Interface for Sensitive Detection of MiRNA 155. Anal Chem. 2021 08 10; 93(31):11019-11024. Wu CJ, Huang SQ, Wang YY, Chai YQ, Yuan R, Yang X. PMID: 34324804.
      View in: PubMed   Mentions: 4     Fields:    
    50. Field-effect at electrical contacts to two-dimensional materials. Nano Res. 2021; 14(12):4894-4900. Guo Y, Sun Y, Tang A, Wang CH, Zhao Y, Bai M, Xu S, Xu Z, Tang T, Wang S, Qiu C, Xu K, Peng X, Han J, Pop E, Chai Y. PMID: 34336143; PMCID: PMC8316888.
      View in: PubMed   Mentions: 1  
    51. Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika virus. EMBO Rep. 2021 08 04; 22(8):e51978. Ma L, Wang J, Ge J, Wang Y, Zhang W, Du Y, Luo J, Li Y, Wang F, Fan G, Chen R, Yao B, Zhao Z, Guo ML, Kim WK, Chai Y, Chen JF. PMID: 34232545; PMCID: PMC8344882.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    52. Arid1a regulates cell cycle exit of transit-amplifying cells by inhibiting the Aurka-Cdk1 axis in mouse incisor. Development. 2021 04 15; 148(8). Du J, Jing J, Chen S, Yuan Y, Feng J, Ho TV, Sehgal P, Xu J, Jiang X, Chai Y. PMID: 33766930; PMCID: PMC8077510.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    53. Arid1a-Plagl1-Hh signaling is indispensable for differentiation-associated cell cycle arrest of tooth root progenitors. Cell Rep. 2021 04 06; 35(1):108964. Du J, Jing J, Yuan Y, Feng J, Han X, Chen S, Li X, Peng W, Xu J, Ho TV, Jiang X, Chai Y. PMID: 33826897; PMCID: PMC8132592.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    54. Mesenchymal stem cells and three-dimensional-osteoconductive scaffold regenerate calvarial bone in critical size defects in swine. Stem Cells Transl Med. 2021 08; 10(8):1170-1183. Johnson ZM, Yuan Y, Li X, Jashashvili T, Jamieson M, Urata M, Chen Y, Chai Y. PMID: 33794062; PMCID: PMC8284781.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    55. Lhx6 regulates canonical Wnt signaling to control the fate of mesenchymal progenitor cells during mouse molar root patterning. PLoS Genet. 2021 02; 17(2):e1009320. He J, Jing J, Feng J, Han X, Yuan Y, Guo T, Pei F, Ma Y, Cho C, Ho TV, Chai Y. PMID: 33596195; PMCID: PMC7920342.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
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    198. A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 2005 Jan; 3(1):e11. Jamora C, Lee P, Kocieniewski P, Azhar M, Hosokawa R, Chai Y, Fuchs E. PMID: 15630473; PMCID: PMC539061.
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    199. Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development. 2003 Nov; 130(21):5269-80. Ito Y, Yeo JY, Chytil A, Han J, Bringas P, Nakajima A, Shuler CF, Moses HL, Chai Y. PMID: 12975342.
      View in: PubMed   Mentions: 169     Fields:    Translation:HumansAnimalsCells
    200. Cranial neural crest-derived mesenchymal proliferation is regulated by Msx1-mediated p19(INK4d) expression during odontogenesis. Dev Biol. 2003 Sep 01; 261(1):183-96. Han J, Ito Y, Yeo JY, Sucov HM, Maas R, Chai Y. PMID: 12941628.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    201. TGF-beta3-dependent SMAD2 phosphorylation and inhibition of MEE proliferation during palatal fusion. Dev Dyn. 2003 Jul; 227(3):387-94. Cui XM, Chai Y, Chen J, Yamamoto T, Ito Y, Bringas P, Shuler CF. PMID: 12815624.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    202. Timing of odontogenic neural crest cell migration and tooth-forming capability in mice. Dev Dyn. 2003 Apr; 226(4):713-8. Zhang Y, Wang S, Song Y, Han J, Chai Y, Chen Y. PMID: 12666208.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    203. Prospects for tooth regeneration in the 21st century: a perspective. Microsc Res Tech. 2003 Apr 01; 60(5):469-79. Chai Y, Slavkin HC. PMID: 12619122.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    204. Developmental expression of Smad1-7 suggests critical function of TGF-beta/BMP signaling in regulating epithelial-mesenchymal interaction during tooth morphogenesis. Int J Dev Biol. 2003 Feb; 47(1):31-9. Xu X, Jeong L, Han J, Ito Y, Bringas P, Chai Y. PMID: 12653249.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    205. TGF-beta signaling and its functional significance in regulating the fate of cranial neural crest cells. Crit Rev Oral Biol Med. 2003; 14(2):78-88. Chai Y, Ito Y, Han J. PMID: 12764071.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    206. Developmental patterning of the circumvallate papilla. Int J Dev Biol. 2002 Aug; 46(5):755-63. Jitpukdeebodintra S, Chai Y, Snead ML. PMID: 12216988.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    207. Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development. Dev Dyn. 2002 May; 224(1):69-78. Ito Y, Bringas P, Mogharei A, Zhao J, Deng C, Chai Y. PMID: 11984875.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    208. Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) mice. Cells Tissues Organs. 2002; 170(2-3):83-98. Jaskoll T, Zhou YM, Chai Y, Makarenkova HP, Collinson JM, West JD, Hajihosseini MK, Lee J, Melnick M. PMID: 11731698.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
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