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Zika virus infection disrupts neurovascular development and results in postnatal microcephaly with brain damage. Development. 2016 11 15; 143(22):4127-4136.
Shao Q, Herrlinger S, Yang SL, Lai F, Moore JM, Brindley MA, Chen JF. PMID: 27729407.
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58 Fields:
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A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy. Sci Adv. 2016 09; 2(9):e1601167.
Yang M, Liang C, Swaminathan K, Herrlinger S, Lai F, Shiekhattar R, Chen JF. PMID: 27617292.
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91 Fields:
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MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. Dev Biol. 2015 Dec 01; 408(1):140-50.
Yang SL, Yang M, Herrlinger S, Liang C, Lai F, Chen JF. PMID: 26441343.
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13 Fields:
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AnimalsCells
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Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 01; 142(9):1616-27.
Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF. PMID: 25922525.
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37 Fields:
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Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014 May 30; 5:3885.
Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L. PMID: 24875059.
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59 Fields:
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A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 2014 May; 74(5):483-97.
Harmacek L, Watkins-Chow DE, Chen J, Jones KL, Pavan WJ, Salbaum JM, Niswander L. PMID: 24170322.
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17 Fields:
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The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15; 26(8):803-15.
Chen J, Lai F, Niswander L. PMID: 22508726.
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42 Fields:
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AnimalsCells
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CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res. 2012 Mar 16; 110(6):818-30.
Huang ZP, Young Seok H, Zhou B, Chen J, Chen JF, Tao Y, Pu WT, Wang DZ. PMID: 22343712.
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12 Fields:
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HumansAnimalsCells
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The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly. J Cell Biol. 2011 Aug 22; 194(4):551-65.
Tao Y, Neppl RL, Huang ZP, Chen J, Tang RH, Cao R, Zhang Y, Jin SW, Wang DZ. PMID: 21859860.
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51 Fields:
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Transgenic overexpression of miR-133a in skeletal muscle. BMC Musculoskelet Disord. 2011 May 26; 12:115.
Deng Z, Chen JF, Wang DZ. PMID: 21615921.
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19 Fields:
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Loss of microRNAs in neural crest leads to cardiovascular syndromes resembling human congenital heart defects. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2575-86.
Huang ZP, Chen JF, Regan JN, Maguire CT, Tang RH, Dong XR, Majesky MW, Wang DZ. PMID: 20884876.
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33 Fields:
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microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. J Cell Biol. 2010 Sep 06; 190(5):867-79.
Chen JF, Tao Y, Li J, Deng Z, Yan Z, Xiao X, Wang DZ. PMID: 20819939.
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228 Fields:
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MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep; 119(9):2772-86.
Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ. PMID: 19726871.
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336 Fields:
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microRNAs and muscle disorders. J Cell Sci. 2009 Jan 01; 122(Pt 1):13-20.
Chen JF, Callis TE, Wang DZ. PMID: 19092056.
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63 Fields:
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HumansAnimalsCells
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Myocardin marks the earliest cardiac gene expression and plays an important role in heart development. Anat Rec (Hoboken). 2008 Oct; 291(10):1200-11.
Chen JF, Wang S, Wu Q, Cao D, Nguyen T, Chen Y, Wang DZ. PMID: 18780304.
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5 Fields:
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Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6):2111-6.
Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ. PMID: 18256189.
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236 Fields:
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Muscling through the microRNA world. Exp Biol Med (Maywood). 2008 Feb; 233(2):131-8.
Callis TE, Deng Z, Chen JF, Wang DZ. PMID: 18222968.
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59 Fields:
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Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy. J Mol Cell Cardiol. 2007 Jun; 42(6):1137-41.
Tatsuguchi M, Seok HY, Callis TE, Thomson JM, Chen JF, Newman M, Rojas M, Hammond SM, Wang DZ. PMID: 17498736.
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176 Fields:
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MicroRNAs in skeletal and cardiac muscle development. DNA Cell Biol. 2007 Apr; 26(4):219-25.
Callis TE, Chen JF, Wang DZ. PMID: 17465888.
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63 Fields:
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The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet. 2006 Feb; 38(2):228-33.
Chen JF, Mandel EM, Thomson JM, Wu Q, Callis TE, Hammond SM, Conlon FL, Wang DZ. PMID: 16380711.
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1086 Fields:
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AnimalsCells
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The HopPtoF locus of Pseudomonas syringae pv. tomato DC3000 encodes a type III chaperone and a cognate effector. Mol Plant Microbe Interact. 2004 May; 17(5):447-55.
Shan L, Oh HS, Chen J, Guo M, Zhou J, Alfano JR, Collmer A, Jia X, Tang X. PMID: 15141948.
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14 Fields:
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AnimalsCells