Loading...

Hyungjin Eoh, PhD

Title(s)Assistant Professor of Molecular Microbiology & Immunology
AddressZNI 537 1501 San Pablo
Health Sciences Campus
Los Angeles CA 90033
ORCID ORCID Icon0000-0001-8774-6400 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Awards and Honors
    Donald E. & Delia B. Baxter Foundation2016  - 2017Junior Faculty Award
    L.K Whittier Foundation2017  - 2018Whitter Health Sciences Initiative
    Wright Foundation2018  - 2019Wright Foundation Research Awards
    American Lung Association2020  - 2022Innovation Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    PknG mediated tailoring Mycobacterium tuberculosis adaptive metabolism is required for the persister formation
    NIH/NIAID R56AI143870Sep 10, 2019 - Aug 31, 2020
    Role: Principal Investigator
    Metabolic compensation in Mycobacterium tuberculosis for the formation of persisters
    NIH/NIAID R21AI139386Mar 1, 2019 - Feb 28, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii. Nat Microbiol. 2020 Sep; 5(9):1134-1143. Luna B, Trebosc V, Lee B, Bakowski M, Ulhaq A, Yan J, Lu P, Cheng J, Nielsen T, Lim J, Ketphan W, Eoh H, McNamara C, Skandalis N, She R, Kemmer C, Lociuro S, Dale GE, Spellberg B. PMID: 32514072.
      View in: PubMed   Mentions:    Fields:    
    2. Oncogenic human herpesvirus hijacks proline metabolism for tumorigenesis. Proc Natl Acad Sci U S A. 2020 04 07; 117(14):8083-8093. Choi UY, Lee JJ, Park A, Zhu W, Lee HR, Choi YJ, Yoo JS, Yu C, Feng P, Gao SJ, Chen S, Eoh H, Jung JU. PMID: 32213586.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis. Nat Commun. 2019 07 02; 10(1):2928. Lee JJ, Lee SK, Song N, Nathan TO, Swarts BM, Eum SY, Ehrt S, Cho SN, Eoh H. PMID: 31266959.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    4. Inhibiting the stringent response blocks Mycobacterium tuberculosis entry into quiescence and reduces persistence. Sci Adv. 2019 03; 5(3):eaav2104. Dutta NK, Klinkenberg LG, Vazquez MJ, Segura-Carro D, Colmenarejo G, Ramon F, Rodriguez-Miquel B, Mata-Cantero L, Porras-De Francisco E, Chuang YM, Rubin H, Lee JJ, Eoh H, Bader JS, Perez-Herran E, Mendoza-Losana A, Karakousis PC. PMID: 30906866.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    5. Bacterial Protein Reshapes Host Defense toward Antiviral Responses. Mol Cell. 2018 08 16; 71(4):483-484. Eoh H, Jung JU. PMID: 30118676.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    6. Glutamate mediated metabolic neutralization mitigates propionate toxicity in intracellular Mycobacterium tuberculosis. Sci Rep. 2018 05 31; 8(1):8506. Lee JJ, Lim J, Gao S, Lawson CP, Odell M, Raheem S, Woo J, Kang SH, Kang SS, Jeon BY, Eoh H. PMID: 29855554.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    7. Endothelial lineage-specific interaction of Mycobacterium tuberculosis with the blood and lymphatic systems. Tuberculosis (Edinb). 2018 07; 111:1-7. Kim PM, Lee JJ, Choi D, Eoh H, Hong YK. PMID: 30029892.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. TRIM56-mediated monoubiquitination of cGAS for cytosolic DNA sensing. Nat Commun. 2018 02 09; 9(1):613. Seo GJ, Kim C, Shin WJ, Sklan EH, Eoh H, Jung JU. PMID: 29426904.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    9. A Critical Role of Glutamine and Asparagine ?-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus. mBio. 2017 08 15; 8(4). Zhu Y, Li T, Ramos da Silva S, Lee JJ, Lu C, Eoh H, Jung JU, Gao SJ. PMID: 28811348.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. ?20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):7112-7117. Wu WL, Grotefend CR, Tsai MT, Wang YL, Radic V, Eoh H, Huang IC. PMID: 28630320.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    11. Metabolic anticipation in Mycobacterium tuberculosis. Nat Microbiol. 2017 May 22; 2:17084. Eoh H, Wang Z, Layre E, Rath P, Morris R, Branch Moody D, Rhee KY. PMID: 28530656.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    12. Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2225-E2232. Puckett S, Trujillo C, Wang Z, Eoh H, Ioerger TR, Krieger I, Sacchettini J, Schnappinger D, Rhee KY, Ehrt S. PMID: 28265055.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    13. Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis. ACS Infect Dis. 2016 12 09; 2(12):958-968. Evans JC, Trujillo C, Wang Z, Eoh H, Ehrt S, Schnappinger D, Boshoff HI, Rhee KY, Barry CE, Mizrahi V. PMID: 27676316.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    14. Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis. Cell Rep. 2016 Jan 26; 14(3):572-585. Saini V, Cumming BM, Guidry L, Lamprecht DA, Adamson JH, Reddy VP, Chinta KC, Mazorodze JH, Glasgow JN, Richard-Greenblatt M, Gomez-Velasco A, Bach H, Av-Gay Y, Eoh H, Rhee K, Steyn AJC. PMID: 26774486.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    15. Effects of fluconazole on the metabolomic profile of Candida albicans. J Antimicrob Chemother. 2016 Mar; 71(3):635-40. Katragkou A, Alexander EL, Eoh H, Raheem SK, Roilides E, Walsh TJ. PMID: 26668236.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    16. Two enzymes with redundant fructose bisphosphatase activity sustain gluconeogenesis and virulence in Mycobacterium tuberculosis. Nat Commun. 2015 Aug 10; 6:7912. Ganapathy U, Marrero J, Calhoun S, Eoh H, de Carvalho LPS, Rhee K, Ehrt S. PMID: 26258286.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    17. Metabolomics: a window into the adaptive physiology of Mycobacterium tuberculosis. Tuberculosis (Edinb). 2014 Dec; 94(6):538-43. Eoh H. PMID: 25172023.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis. PLoS Pathog. 2014 May; 10(5):e1004144. Puckett S, Trujillo C, Eoh H, Marrero J, Spencer J, Jackson M, Schnappinger D, Rhee K, Ehrt S. PMID: 24851864.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    19. Methylcitrate cycle defines the bactericidal essentiality of isocitrate lyase for survival of Mycobacterium tuberculosis on fatty acids. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):4976-81. Eoh H, Rhee KY. PMID: 24639517.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    20. Allostery and compartmentalization: old but not forgotten. Curr Opin Microbiol. 2014 Apr; 18:23-9. Eoh H, Rhee KY. PMID: 24607642.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    21. Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6554-9. Eoh H, Rhee KY. PMID: 23576728.
      View in: PubMed   Mentions: 87     Fields:    Translation:Cells
    22. Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis. Yonsei Med J. 2011 Nov; 52(6):1008-15. Jeon BY, Eoh H, Ha SJ, Bang H, Kim SC, Sung YC, Cho SN. PMID: 22028167.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    23. Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS Pathog. 2011 Sep; 7(9):e1002264. Woong Park S, Klotzsche M, Wilson DJ, Boshoff HI, Eoh H, Manjunatha U, Blumenthal A, Rhee K, Barry CE, Aldrich CC, Ehrt S, Schnappinger D. PMID: 21980288.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    24. Regulation of polar peptidoglycan biosynthesis by Wag31 phosphorylation in mycobacteria. BMC Microbiol. 2010 Dec 29; 10:327. Jani C, Eoh H, Lee JJ, Hamasha K, Sahana MB, Han JS, Nyayapathy S, Lee JY, Suh JW, Lee SH, Rehse SJ, Crick DC, Kang CM. PMID: 21190553.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    25. Expression and validation of D-erythrulose 1-phosphate dehydrogenase from Brucella abortus: a diagnostic reagent for bovine brucellosis. J Vet Diagn Invest. 2010 Jul; 22(4):524-30. Eoh H, Jeon BY, Kim Z, Kim SC, Cho SN. PMID: 20622221.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    26. Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. Chem Biol. 2010 Feb 26; 17(2):117-22. Narayanasamy P, Eoh H, Brennan PJ, Crick DC. PMID: 20189102.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    27. Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens. Chem Biol. 2009 Dec 24; 16(12):1230-9. Eoh H, Narayanasamy P, Brown AC, Parish T, Brennan PJ, Crick DC. PMID: 20064433.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    28. The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target. Tuberculosis (Edinb). 2009 Jan; 89(1):1-11. Eoh H, Brennan PJ, Crick DC. PMID: 18793870.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    29. Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. Bioorg Med Chem Lett. 2008 Oct 01; 18(19):5320-3. Mao J, Eoh H, He R, Wang Y, Wan B, Franzblau SG, Crick DC, Kozikowski AP. PMID: 18783951.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    30. Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE. Tetrahedron Lett. 2008 Jul 21; 49(29-30):4461-4463. Narayanasamy P, Eoh H, Crick DC. PMID: 19088853.
      View in: PubMed   Mentions: 9     Fields:    
    31. Characterization of the Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: potential for drug development. J Bacteriol. 2007 Dec; 189(24):8922-7. Eoh H, Brown AC, Buetow L, Hunter WN, Parish T, Kaur D, Brennan PJ, Crick DC. PMID: 17921290.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    32. Antigens secreted from Mycobacterium tuberculosis: identification by proteomics approach and test for diagnostic marker. Proteomics. 2004 Nov; 4(11):3299-307. Bahk YY, Kim SA, Kim JS, Euh HJ, Bai GH, Cho SN, Kim YS. PMID: 15378731.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    Hyungjin's Networks
    Concepts (213)
    Derived automatically from this person's publications.
    _
    Co-Authors (3)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _