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Translating "Big Data" in Oncology for Clinical Benefit: Progress or Paralysis. Cancer Res. 2022 06 06; 82(11):2072-2075.
Barker AD, Lee JSH. PMID: 35416976; PMCID: PMC9306452.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Adaptation of Imaging Mass Cytometry to Explore the Single Cell Alloimmune Landscape of Liver Transplant Rejection. Front Immunol. 2022; 13:831103.
Ung N, Goldbeck C, Man C, Hoeflich J, Sun R, Barbetta A, Matasci N, Katz J, Lee JSH, Chopra S, Asgharzadeh S, Warren M, Sher L, Kohli R, Akbari O, Genyk Y, Emamaullee J. PMID: 35432320; PMCID: PMC9009043.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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A field guide to cultivating computational biology. PLoS Biol. 2021 10; 19(10):e3001419.
Way GP, Greene CS, Carninci P, Carvalho BS, de Hoon M, Finley SD, Gosline SJC, L? Cao KA, Lee JSH, Marchionni L, Robine N, Sindi SS, Theis FJ, Yang JYH, Carpenter AE, Fertig EJ. PMID: 34618807; PMCID: PMC8525744.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Potential association between public medical insurance, waitlist mortality, and utilization of living donor liver transplantation: An analysis of the Scientific Registry of Transplant Recipients. Clin Transplant. 2021 10; 35(10):e14418.
Emamaullee JA, Aljehani M, Hogen RVT, Zhou K, Lee JSH, Sher LS, Genyk YS. PMID: 34236113.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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BloodPAC Data Commons for Liquid Biopsy Data. JCO Clin Cancer Inform. 2021 04; 5:479-486.
Grossman RL, Dry JR, Hanlon SE, Johann DJ, Kolatkar A, Lee JSH, Meyer C, Salvatore L, Wells W, Leiman L. PMID: 33929890; PMCID: PMC8140805.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Paradoxical androgen receptor regulation by small molecule enantiomers. Proc Natl Acad Sci U S A. 2021 03 23; 118(12).
Patsch K, Liu C, Zapotoczny G, Sun Y, Sura H, Ung N, Sun RX, Haliday B, Yu C, Aljehani M, Lee JSH, Kashemirov BA, Agus DB, McKenna CE, Ruderman D. PMID: 33741738; PMCID: PMC8000581.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Real-World Outcomes for Patients Treated With Immune Checkpoint Inhibitors in the Veterans Affairs System. JCO Clin Cancer Inform. 2020 10; 4:918-928.
La J, Cheng D, Brophy MT, Do NV, Lee JSH, Tuck D, Fillmore NR. PMID: 33074743; PMCID: PMC7608595.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based ctDNA Assays: A Joint Consensus Recommendation of the BloodPAC's Analytical Variables Working Group. Clin Chem. 2020 09 01; 66(9):1156-1166.
Godsey JH, Silvestro A, Barrett JC, Bramlett K, Chudova D, Deras I, Dickey J, Hicks J, Johann DJ, Leary R, Lee JSH, McMullen J, McShane L, Nakamura K, Richardson AO, Ryder M, Simmons J, Tanzella K, Yee L, Leiman LC. PMID: 32870995; PMCID: PMC7462123.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Use of Wearable Activity Tracker in Patients With Cancer Undergoing Chemotherapy: Toward Evaluating Risk of Unplanned Health Care Encounters. JCO Clin Cancer Inform. 2020 09; 4:839-853.
Nilanon T, Nocera LP, Martin AS, Kolatkar A, May M, Hasnain Z, Ueno NT, Yennu S, Alexander A, Mejia AE, Boles RW, Li M, Lee JSH, Hanlon SE, Cozzens Philips FA, Quinn DI, Newton PK, Broderick J, Shahabi C, Kuhn P, Nieva JJ. PMID: 32970482; PMCID: PMC7531613.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Quantified Kinematics to Evaluate Patient Chemotherapy Risks in Clinic. JCO Clin Cancer Inform. 2020 06; 4:583-601.
Hasnain Z, Nilanon T, Li M, Mejia A, Kolatkar A, Nocera L, Shahabi C, Cozzens Philips FA, Lee JSH, Hanlon SE, Vaidya P, Ueno NT, Yennu S, Newton PK, Kuhn P, Nieva J. PMID: 32598179; PMCID: PMC7328110.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases. Clin Pharmacol Ther. 2020 04; 107(4):730-734.
Febbo PG, Martin AM, Scher HI, Barrett JC, Beaver JA, Beresford PJ, Blumenthal GM, Bramlett K, Compton C, Dittamore R, Eberhard DA, Edelstein D, Godsey J, Gruen A, Hanlon SE, Hicks J, Hovelson D, Hullings M, Johann D, Johnson J, Kolatkar A, Kuhn P, Levine R, Martini JF, Miller DP, Moore C, Moy B, Pathak A, Philip R, Reese D, Royalty W, Ryder M, Sakul H, Salvatore LM, Schade A, Silvestro A, Simmons JK, Simons J, Singh Bhan S, Smalley MD, Somiari SB, Talasaz A, Tewari M, Tseng HR, Vinson J, Wells W, Welsh A, Grossman RL, Lee JSH, Leiman LC. PMID: 32017048; PMCID: PMC7158216.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer. Oncotarget. 2019 Dec 17; 10(66):7016-7030.
Gerdtsson AS, Thiele JA, Shishido SN, Zheng S, Schaffer R, Bethel K, Curley S, Lenz HJ, Hanna DL, Nieva J, Kolatkar A, Ruiz C, Rodriguez-Lee M, Oakley Iii GJ, Lee JSH, Hicks J, Kuhn P. PMID: 31903162; PMCID: PMC6925029.
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PubMed Mentions:
8 Fields:
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Contribution Of Care Source To Cancer Treatment Cost Variation In The US Military Health System. Health Aff (Millwood). 2019 08; 38(8):1335-1342.
Eaglehouse YL, Aljehani M, Georg MW, Castellanos O, Lee JSH, Seabury SA, Shriver CD, Zhu K. PMID: 31381409.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Patient reported outcomes can improve performance status assessment: a pilot study. J Patient Rep Outcomes. 2019 Jul 16; 3(1):41.
Broderick JE, May M, Schwartz JE, Li M, Mejia A, Nocera L, Kolatkar A, Ueno NT, Yennu S, Lee JSH, Hanlon SE, Cozzens Philips FA, Shahabi C, Kuhn P, Nieva J. PMID: 31313047; PMCID: PMC6635569.
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PubMed Mentions:
11 Fields:
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Harnessing the Power of Collaboration and Training Within Clinical Data Science to Generate Real-World Evidence in the Era of Precision Oncology. Clin Pharmacol Ther. 2019 07; 106(1):60-66.
Rivera DR, Lee JSH, Hsu E, Khoury MJ, Meng F, Olivero O, Penberthy L, Tourassi GD. PMID: 31166005.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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From Discovery to Practice and Survivorship: Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patients. Clin Pharmacol Ther. 2019 07; 106(1):52-57.
Lee JSH, Darcy KM, Hu H, Casablanca Y, Conrads TP, Dalgard CL, Freymann JB, Hanlon SE, Huang GD, Kvecher L, Maxwell GL, Meng F, Moncur JT, Turner C, Wells JM, Wilkerson MD, Zhu K, Ramoni RB, Shriver CD. PMID: 30838639; PMCID: PMC6617989.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Tumor cell density regulates matrix metalloproteinases for enhanced migration. Oncotarget. 2018 Aug 24; 9(66):32556-32569.
Jayatilaka H, Umanzor FG, Shah V, Meirson T, Russo G, Starich B, Tyle P, Lee JSH, Khatau S, Gil-Henn H, Wirtz D. PMID: 30220965; PMCID: PMC6135685.
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PubMed Mentions:
13 Fields:
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Data Harmonization for a Molecularly Driven Health System. Cell. 2018 08 23; 174(5):1045-1048.
Lee JS, Kibbe WA, Grossman RL. PMID: 30142341.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Residual tissue repositories as a resource for population-based cancer proteomic studies. Clin Proteomics. 2018; 15:26.
Piehowski PD, Petyuk VA, Sontag RL, Gritsenko MA, Weitz KK, Fillmore TL, Moon J, Makhlouf H, Chuaqui RF, Boja ES, Rodriguez H, Lee JSH, Smith RD, Carrick DM, Liu T, Rodland KD. PMID: 30087585; PMCID: PMC6074037.
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PubMed Mentions:
17
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A comparison of methods to assess cell mechanical properties. Nat Methods. 2018 07; 15(7):491-498.
Wu PH, Aroush DR, Asnacios A, Chen WC, Dokukin ME, Doss BL, Durand-Smet P, Ekpenyong A, Guck J, Guz NV, Janmey PA, Lee JSH, Moore NM, Ott A, Poh YC, Ros R, Sander M, Sokolov I, Staunton JR, Wang N, Whyte G, Wirtz D. PMID: 29915189; PMCID: PMC6582221.
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PubMed Mentions:
211 Fields:
Translation:
HumansCells
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Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation. Clin Transl Sci. 2018 05; 11(3):267-276.
Keating SM, Taylor DL, Plant AL, Litwack ED, Kuhn P, Greenspan EJ, Hartshorn CM, Sigman CC, Kelloff GJ, Chang DD, Friberg G, Lee JSH, Kuida K. PMID: 29498218; PMCID: PMC5944591.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Aligned fibers direct collective cell migration to engineer closing and nonclosing wound gaps. Mol Biol Cell. 2017 Sep 15; 28(19):2579-2588.
Sharma P, Ng C, Jana A, Padhi A, Szymanski P, Lee JSH, Behkam B, Nain AS. PMID: 28747440; PMCID: PMC5597329.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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Biophysical and biomolecular determination of cellular age in humans. Nat Biomed Eng. 2017 Jul; 1(7).
Phillip JM, Wu PH, Gilkes DM, Williams W, McGovern S, Daya J, Chen J, Aifuwa I, Lee JSH, Fan R, Walston J, Wirtz D. PMID: 31372309; PMCID: PMC6675017.
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PubMed Mentions:
38 Fields:
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Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration. Nat Commun. 2017 05 26; 8:15584.
Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D. PMID: 28548090; PMCID: PMC5458548.
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PubMed Mentions:
81 Fields:
Translation:
HumansAnimalsCells
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Cancer Therapy: Shooting for the Moon. Clin Pharmacol Ther. 2017 05; 101(5):552-558.
Lee J, Blumenthal GM, Hohl RJ, Huang SM. PMID: 28418166; PMCID: PMC5525193.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium. Clin Pharmacol Ther. 2017 May; 101(5):589-592.
Grossman RL, Abel B, Angiuoli S, Barrett JC, Bassett D, Bramlett K, Blumenthal GM, Carlsson A, Cortese R, DiGiovanna J, Davis-Dusenbery B, Dittamore R, Eberhard DA, Febbo P, Fitzsimons M, Flamig Z, Godsey J, Goswami J, Gruen A, Ortuño F, Han J, Hayes D, Hicks J, Holloway D, Hovelson D, Johnson J, Juhl H, Kalamegham R, Kamal R, Kang Q, Kelloff GJ, Klozenbuecher M, Kolatkar A, Kuhn P, Langone K, Leary R, Loverso P, Manmathan H, Martin AM, Martini J, Miller D, Mitchell M, Morgan T, Mulpuri R, Nguyen T, Otto G, Pathak A, Peters E, Philip R, Posadas E, Reese D, Reese MG, Robinson D, Dei Rossi A, Sakul H, Schageman J, Singh S, Scher HI, Schmitt K, Silvestro A, Simmons J, Simmons T, Sislow J, Talasaz A, Tang P, Tewari M, Tomlins S, Toukhy H, Tseng HR, Tuck M, Tzou A, Vinson J, Wang Y, Wells W, Welsh A, Wilbanks J, Wolf J, Young L, Lee J, Leiman LC. PMID: 28187516; PMCID: PMC5525192.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Innovative Methodologies to Drive Enrollment of Molecularly Defined Patient Populations for Diagnostic-Enabled Basket Studies. Journal of Precision Medicine. 2017; (5):34-39.
Kowak, E., P. Multani, W. McCarthy, Z. Hornby, G. Li, R. Landin, M. Yamamoto, J. Christiansen, J.S.H. Lee, J. Lim.
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Determination of Cellular Biological Age in Health and Disease. Nature Biomedical Engineering. 2017; (1):0093.
Phillip, J.M., P. Wu, D.M. Gilkes, W. Williams, S. McGovern, J. Daya, J. Chen, R. Fan, J.S.H. Lee, J. Walston, D. Wirtz.
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Advancing Convergence and Innovation in Cancer Research: National Cancer Institute Center for Strategic Scientific Initiatives (CSSI). Electrochemical Society Transactions. 2017; 10(80):1315-1318.
Elder, S.G. and J.S.H. Lee. .
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Proliferation and enrichment of CD133(+) glioblastoma cancer stem cells on 3D chitosan-alginate scaffolds. Biomaterials. 2014 Nov; 35(33):9137-43.
Kievit FM, Florczyk SJ, Leung MC, Wang K, Wu JD, Silber JR, Ellenbogen RG, Lee JS, Zhang M. PMID: 25109438; PMCID: PMC4167581.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimalsCells
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Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach. Mol Cell Proteomics. 2014 Mar; 13(3):907-17.
Carr SA, Abbatiello SE, Ackermann BL, Borchers C, Domon B, Deutsch EW, Grant RP, Hoofnagle AN, Hüttenhain R, Koomen JM, Liebler DC, Liu T, MacLean B, Mani DR, Mansfield E, Neubert H, Paulovich AG, Reiter L, Vitek O, Aebersold R, Anderson L, Bethem R, Blonder J, Boja E, Botelho J, Boyne M, Bradshaw RA, Bradshaw RA, Burlingame AL, Chan D, Keshishian H, Kuhn E, Kinsinger C, Lee JS, Lee SW, Moritz R, Oses-Prieto J, Rifai N, Ritchie J, Rodriguez H, Srinivas PR, Townsend RR, Van Eyk J, Whiteley G, Wiita A, Weintraub S. PMID: 24443746; PMCID: PMC3945918.
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PubMed Mentions:
222 Fields:
Translation:
HumansAnimals
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Intracellular Particle Tracking Rheometry. CRC Handbook of Imaging in Biological Mechanics. 2014; 381-388.
Dawson, M., Y. Tseng, J.S.H. Lee, K.M. McAndrews.
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Piloting an approach to rapid and automated assessment of a new research initiative: Application to the National Cancer Institute's Provocative Questions initiative. Res Eval. 2013 Dec; 22(5):272-284.
Hsu ER, Williams DE, Dijoseph LG, Schnell JD, Finstad SL, Lee JS, Greenspan EJ, Corrigan JG. PMID: 24808631; PMCID: PMC3814301.
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PubMed Mentions:
1
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Aligned chitosan-polycaprolactone polyblend nanofibers promote the migration of glioblastoma cells. Adv Healthc Mater. 2013 Dec; 2(12):1651-9.
Kievit FM, Cooper A, Jana S, Leung MC, Wang K, Edmondson D, Wood D, Lee JS, Ellenbogen RG, Zhang M. PMID: 23776187; PMCID: PMC3859701.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Functional interplay between the cell cycle and cell phenotypes. Integr Biol (Camb). 2013 Mar; 5(3):523-34.
Chen WC, Wu PH, Phillip JM, Khatau SB, Choi JM, Dallas MR, Konstantopoulos K, Sun SX, Lee JS, Hodzic D, Wirtz D. PMID: 23319145; PMCID: PMC3813296.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Vascular Cell Physiology Under Shear Flow: Role of Cell Mechanics and Mechanotransduction. Mechanical and Chemical Signalling in Angiogenesis, Studies in Mechanobiology, Tissue Engineering, and Biomaterials. 2013; (12):121-141.
Scott, D., W. Tan, J.S.H. Lee, O.J.T. McCarty, M.T. Hinds.
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Considerations in the development of circulating tumor cell technology for clinical use. J Transl Med. 2012 Jul 02; 10:138.
Parkinson DR, Dracopoli N, Petty BG, Compton C, Cristofanilli M, Deisseroth A, Hayes DF, Kapke G, Kumar P, Lee JSh, Liu MC, McCormack R, Mikulski S, Nagahara L, Pantel K, Pearson-White S, Punnoose EA, Roadcap LT, Schade AE, Scher HI, Sigman CC, Kelloff GJ. PMID: 22747748; PMCID: PMC3478228.
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PubMed Mentions:
144 Fields:
Translation:
HumansCells
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The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. PLoS One. 2012; 7(5):e36689.
Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JS, Gerecht S, Wirtz D. PMID: 22574215; PMCID: PMC3344930.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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High-throughput ballistic injection nanorheology to measure cell mechanics. Nat Protoc. 2012 Jan 05; 7(1):155-70.
Wu PH, Hale CM, Chen WC, Lee JS, Tseng Y, Wirtz D. PMID: 22222790; PMCID: PMC4332792.
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PubMed Mentions:
32 Fields:
Translation:
HumansAnimalsCells
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SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization. J Cell Sci. 2011 Dec 15; 124(Pt 24):4267-85.
Hale CM, Chen WC, Khatau SB, Daniels BR, Lee JS, Wirtz D. PMID: 22193958; PMCID: PMC3258110.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Physical oncology. Preface. Phys Biol. 2011 Feb; 8(1):010301.
Lee JS, Wirtz D. PMID: 21368347.
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PubMed Mentions: Fields:
Translation:
Humans
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De-convoluting cancer's complexity: using a 'physical sciences lens' to provide a different (clearer) perspective of cancer. Preface. Phys Biol. 2011 Feb; 8(1):010302.
Moore NM, Kuhn NZ, Hanlon SE, Lee JS, Nagahara LA. PMID: 21368346.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Intra- and Extracellular Microrheology of Endothelial Cells in 3D Matrix. Biological and Medical Physics, Biomedical Engineering: Biophysical Regulation of Vascular Differentiation and Assembly. 2011; (1):69-87.
Fraley, S.I., C.M. Hale, R.J. Bloom, A. Celedon, J.S.H. Lee, D. Wirtz.
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Strategic workshops on cancer nanotechnology. Cancer Res. 2010 Jun 01; 70(11):4265-8.
Nagahara LA, Lee JS, Molnar LK, Panaro NJ, Farrell D, Ptak K, Alper J, Grodzinski P. PMID: 20460532; PMCID: PMC2880215.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Inhibition of tumor-cell invasion with chlorotoxin-bound superparamagnetic nanoparticles. Small. 2009 Feb; 5(2):256-64.
Veiseh O, Gunn JW, Kievit FM, Sun C, Fang C, Lee JS, Zhang M. PMID: 19089837; PMCID: PMC2692352.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimals
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Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Deliv Rev. 2008 Aug 17; 60(11):1252-1265.
Sun C, Lee JSH, Zhang M. PMID: 18558452; PMCID: PMC2702670.
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PubMed Mentions:
456 Fields:
Translation:
HumansAnimals
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Next Generation Nanosolutions for Cancer Treatment and Diagnosis. Cancer and Chemotherapy Reviews. 2008; (3):144-151.
Lee, J.S.H., J. Cheng, K.Y. Kim.
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Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration. Biophys J. 2007 Oct 01; 93(7):2542-52.
Lee JS, Hale CM, Panorchan P, Khatau SB, George JP, Tseng Y, Stewart CL, Hodzic D, Wirtz D. PMID: 17631533; PMCID: PMC1965451.
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PubMed Mentions:
154 Fields:
Translation:
AnimalsCells
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Probing cellular mechanical responses to stimuli using ballistic intracellular nanorheology. Methods Cell Biol. 2007; 83:115-40.
Panorchan P, Lee JS, Daniels BR, Kole TP, Tseng Y, Wirtz D. PMID: 17613307.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix. Biophys J. 2006 Nov 01; 91(9):3499-507.
Panorchan P, Lee JS, Kole TP, Tseng Y, Wirtz D. PMID: 16891369; PMCID: PMC1614481.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow. J Cell Sci. 2006 May 01; 119(Pt 9):1760-8.
Lee JS, Panorchan P, Hale CM, Khatau SB, Kole TP, Tseng Y, Wirtz D. PMID: 16636071.
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PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response. Biochem Biophys Res Commun. 2005 Aug 19; 334(1):183-92.
Tseng Y, Kole TP, Lee JS, Fedorov E, Almo SC, Schafer BW, Wirtz D. PMID: 15992772.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress. Mol Biol Cell. 2005 Feb; 16(2):871-80.
Lee JS, Chang MI, Tseng Y, Wirtz D. PMID: 15548602; PMCID: PMC545918.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Micro-organization and visco-elasticity of the interphase nucleus revealed by particle nanotracking. J Cell Sci. 2004 Apr 15; 117(Pt 10):2159-67.
Tseng Y, Lee JS, Kole TP, Jiang I, Wirtz D. PMID: 15090601.
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PubMed Mentions:
88 Fields:
Translation:
AnimalsCells
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Local Dynamics and Viscoelastic Properties of Cell Biological Systems. Current Opinion in Colloid & Interface Science. 2002; (7):210-217.
Tseng Y., T.P. Kole, S.H.J. Lee, D. Wirtz.