Rohit Kohli

Title(s)Professor of Pediatrics (Clinical Scholar)
SchoolKeck School of Medicine of Usc
AddressCHL 4640 W. Sunset Blvd.
Off Campus
Los Angeles CA 90027
ORCID ORCID Icon0000-0002-0198-7703 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Armed Forces Medical College, Pune, IndiaMBBS1999Medicine
    Northwestern University, Chicago, ILMS2006Clinical Investigation
    Children's Memorial Hospital, Chicago, IL2006Pediatric Gastroenterology
    Children's Memorial Hospital, Chicago, IL2007Transplant Hepatology

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    Dr. Kohli received his medical degree from the Armed Forces Medical College, India in 1999 and his MS in clinical investigation from Northwestern University in 2006. While at Northwestern he first spent three years as a pediatric gastroenterology and hepatology fellow and then subsequently as a transplant hepatology trainee before relocating to the University of Cincinnati in 2007. He was faculty at Cincinnati Children's and leading the pediatric liver transplant program before he again relocated to USC/Children's Hospital Los Angeles in 2016.

    His research work has focused on the pathogenesis of obesity related fatty liver disease (NAFLD). In particular, he has focused upon the role of bile acid signaling as a mechanism for NAFLD resolution after weight loss surgery. His work has also shed light on reactive oxygen stress in the generation and regulation of the extreme stage of this disease; nonalcoholic steatohepatitis (NASH). He has published many peer-reviewed articles including articles in Nature, Nature Reviews, The Journal of Biological Chemistry, Hepatology, Journal of Pediatrics, and The American Journal of Physiology. He is the author of many book chapters and review articles. He also is the recipient of the 2007 George Ferry Young Investigator Award from the Children's Digestive Health and Nutrition Foundation, a Fellowship award from the American Association for the Study of Liver Diseases, Takeda Research Innovation Award from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Foundation. He is currently funded by the NIH as an independent scientist through the R01 mechanism.

    He currently leads The George Donnell Society for Pediatric Scientists at Children's Hospital Los Angeles.
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    Collapse Research 
    Collapse Research Activities and Funding
    NAFLD Improvement after Bariatric Surgery: The role of bile acid signaling
    NIH R01DK100314Apr 1, 2015 - Mar 31, 2020
    Role: Principal Investigator
    Role of Ileum in Reducing Obesity Related Comorbidities
    NIH K08DK084310Sep 1, 2009 - Aug 31, 2013
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Impact of long-term administration of maralixibat on children with cholestasis secondary to Alagille syndrome. Hepatol Commun. 2022 Jun 07. Shneider BL, Spino CA, Kamath BM, Magee JC, Ignacio RV, Huang S, Horslen SP, Molleston JP, Miethke AG, Kohli R, Leung DH, Jensen MK, Loomes KM, Karpen SJ, Mack C, Rosenthal P, Squires RH, Baker A, Rajwal S, Kelly D, Sokol RJ, Thompson RJ, for ChiLDReN and UK IMAGO/IMAGINE Investigators. PMID: 35672955.
      View in: PubMed   Mentions:
    2. Changes in Resting Energy Expenditure After Sleeve Gastrectomy: a Review of the Literature. Obes Surg. 2022 May 03. Abu El Haija M, Kohli R. PMID: 35503157.
      View in: PubMed   Mentions:
    3. Nature or Nurture in the pathogenesis of biliary atresia? J Pediatr. 2022 May 02. Chu C, Kohli R. PMID: 35513068.
      View in: PubMed   Mentions:
    4. Exposure to per- and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis. Environ Health Perspect. 2022 Apr; 130(4):46001. Costello E, Rock S, Stratakis N, Eckel SP, Walker DI, Valvi D, Cserbik D, Jenkins T, Xanthakos SA, Kohli R, Sisley S, Vasiliou V, La Merrill MA, Rosen H, Conti DV, McConnell R, Chatzi L. PMID: 35475652; PMCID: PMC9044977.
      View in: PubMed   Mentions:
    5. Adaptation of Imaging Mass Cytometry to Explore the Single Cell Alloimmune Landscape of Liver Transplant Rejection. Front Immunol. 2022; 13:831103. Ung N, Goldbeck C, Man C, Hoeflich J, Sun R, Barbetta A, Matasci N, Katz J, Lee JSH, Chopra S, Asgharzadeh S, Warren M, Sher L, Kohli R, Akbari O, Genyk Y, Emamaullee J. PMID: 35432320; PMCID: PMC9009043.
      View in: PubMed   Mentions:
    6. Clinical Intervention to Reduce Dietary Sugar does not Impact Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial. J Nutr. 2022 Feb 26. Schmidt KA, Jones RB, Rios C, Corona Y, Berger PK, Plows JF, Alderete TL, Fogel J, Hampson H, Hartiala JA, Cai Z, Allayee H, Nayak KS, Sinatra FR, Harlan G, Pickering TA, Salvy SJ, Mack W, Kohli R, Goran MI. PMID: 35218194.
      View in: PubMed   Mentions:
    7. Clinical Value of Surveillance Biopsies in Pediatric Liver Transplantation. Liver Transpl. 2022 May; 28(5):843-854. Rocque B, Zaldana A, Weaver C, Huang J, Barbetta A, Shakhin V, Goldbeck C, Yanni G, Zielsdorf S, Kwon Y, Etesami K, Genyk Y, Zhou S, Kohli R, Emamaullee J. PMID: 34954868; PMCID: PMC9078451.
      View in: PubMed   Mentions:
    8. The Role of FGF19 and MALRD1 in Enterohepatic Bile Acid Signaling. Front Endocrinol (Lausanne). 2021; 12:799648. Wang LX, Frey MR, Kohli R. PMID: 35116006; PMCID: PMC8804323.
      View in: PubMed   Mentions:
    9. Pediatric NASH therapies: A speedbump on the road to success. Hepatology. 2022 Jan 09. Softic S, Kohli R. PMID: 35000211.
      View in: PubMed   Mentions:
    10. Pediatric Nonalcoholic Fatty Liver Disease. Pediatr Clin North Am. 2021 12; 68(6):1309-1320. Mitsinikos T, Mrowczynski-Hernandez P, Kohli R. PMID: 34736591.
      View in: PubMed   Mentions:
    11. Stratification by obesity class, rather than age, can identify a higher percent of children at risk for non-alcoholic fatty liver disease and metabolic dysfunction. Pediatr Obes. 2022 03; 17(3):e12862. Radulescu A, Dugan AJ, Killian M, Attia SL, Mouzaki M, Fuchs GJ, Kohli R, Bada H, Kern PA, Softic S. PMID: 34662928.
      View in: PubMed   Mentions:    Fields:    
    12. Living Donor Versus Deceased Donor Pediatric Liver Transplantation: A Systematic Review and Meta-analysis. Transplant Direct. 2021 Oct; 7(10):e767. Barbetta A, Butler C, Barhouma S, Hogen R, Rocque B, Goldbeck C, Schilperoort H, Meeberg G, Shapiro J, Kwon YK, Kohli R, Emamaullee J. PMID: 34557584; PMCID: PMC8454909.
      View in: PubMed   Mentions:
    13. Non-invasive biomarkers of Fontan-associated liver disease. JHEP Rep. 2021 Dec; 3(6):100362. Emamaullee J, Khan S, Weaver C, Goldbeck C, Yanni G, Kohli R, Genyk Y, Zhou S, Shillingford N, Sullivan PM, Takao C, Detterich J, Kantor PF, Cleveland JD, Herrington C, Ram Kumar S, Starnes V, Badran S, Patel ND. PMID: 34693238; PMCID: PMC8517550.
      View in: PubMed   Mentions:
    14. A Diet High in Fat and Fructose Induces Early Hepatic Mitochondrial Aging. J Pediatr Gastroenterol Nutr. 2021 07 01; 73(1):99-102. Bramlage KS, Bhattacharjee J, Kirby M, Myronovych A, Gupta R, Gonzalez RS, Xanthakos S, Bove K, Kohli R. PMID: 34135298; PMCID: PMC8549102.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    15. PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity. Nutrients. 2021 May 12; 13(5). Jones RB, Arenaza L, Rios C, Plows JF, Berger PK, Alderete TL, Fogel JL, Nayak K, Mohamed P, Hwang D, Palmer S, Sinatra F, Allayee H, Kohli R, Goran MI. PMID: 34065978; PMCID: PMC8151324.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Hepatic Ago2 Regulates PPARα for Oxidative Metabolism Linked to Glycemic Control in Obesity and Post Bariatric Surgery. Endocrinology. 2021 04 01; 162(4). Bhattacharjee J, Borra VJ, Salem ESB, Zhang C, Murakami K, Gill RK, Kim A, Kim JK, Salazar-Gonzalez RM, Warren M, Kohli R, Nakamura T. PMID: 33567453; PMCID: PMC7875175.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    17. Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis. Hepatology. 2020 11; 72(5):1586-1604. Kumar S, Verma AK, Rani R, Sharma A, Wang J, Shah SA, Behari J, Salazar Gonzalez R, Kohli R, Gandhi CR. PMID: 32031683; PMCID: PMC8025692.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    18. Assessment of the role of FGF15 in mediating the metabolic outcomes of murine Vertical Sleeve Gastrectomy (VSG). Am J Physiol Gastrointest Liver Physiol. 2020 Sep 23. Myronovych A, Bhattacharjee J, Salazar-Gonzalez RM, Tan B, Mowery S, Ferguson D, Ryan KK, Zhang W, Zhao X, Oehrle M, Setchell KD, Seeley RJ, Sandoval DA, Kohli R. PMID: 32967428; PMCID: PMC7792670.
      View in: PubMed   Mentions: 1     Fields:    
    19. Emerging New Diagnostic Modalities and Therapies of Nonalcoholic Fatty Liver Disease. Curr Gastroenterol Rep. 2020 Aug 19; 22(10):52. Lin CH, Kohli R. PMID: 32814993.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic steatohepatitis. Sci Rep. 2020 04 21; 10(1):6689. Xi D, Bhattacharjee J, Salazar-Gonzalez RM, Park S, Jang A, Warren M, Merritt R, Michail S, Bouret S, Kohli R. PMID: 32317687; PMCID: PMC7174355.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Initial assessment and ongoing monitoring of lysosomal acid lipase deficiency in children and adults: Consensus recommendations from an international collaborative working group. Mol Genet Metab. 2020 02; 129(2):59-66. Kohli R, Ratziu V, Fiel MI, Waldmann E, Wilson DP, Balwani M. PMID: 31767214.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    22. When the beverage is sweet, how does the liver feel? Curr Treat Options Pediatr. 2019 Dec; 5(4):458-465. Xi D, Kohli R. PMID: 33312845; PMCID: PMC7731634.
      View in: PubMed   Mentions:
    23. Designing Clinical Trials in Pediatric Nonalcoholic Steatohepatitis: Tips for Patient Selection and Appropriate Endpoints. Hepatol Commun. 2019 Dec; 3(12):1563-1570. Alkhouri N, Kohli R, Feldstein AE. PMID: 31832567; PMCID: PMC6887671.
      View in: PubMed   Mentions: 4  
    24. Severe Late-Onset Acute Cellular Rejection in a Pediatric Patient With Isolated Small Intestinal Transplant Rescued With Aggressive Immunosuppressive Approach: A Case Report. Transplant Proc. 2019 Nov; 51(9):3181-3185. Narang A, Xi D, Mitsinikos T, Genyk Y, Thomas D, Kohli R, Lin CH, Soufi N, Warren M, Merritt R, Yanni G. PMID: 31711586.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. Immunologic benefit of maternal donors in pediatric living donor liver transplantation. Pediatr Transplant. 2019 11; 23(7):e13560. Kim MH, Akbari O, Genyk Y, Kohli R, Emamaullee J. PMID: 31402535.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Case series and systematic review of acquired diaphragmatic hernia after liver transplantation. Pediatr Transplant. 2018 12; 22(8):e13296. Emamaullee JA, Nekrasov V, Gilmour S, Kneteman N, Yanni G, Kohli R, Thomas D, Genyk Y. PMID: 30280450.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Postprandial Uridine Physiology Is Altered by Obesity. Gastroenterology. 2018 11; 155(5):1645-1646. Kohli R, Bhattacharjee J, Inge TH. PMID: 30142337; PMCID: PMC6428419.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    28. What's cold got to do with it? Cold-induced thermogenesis and microbiome modification may be regulated by bile acid physiology. Hepatology. 2018 10; 68(4):1644-1646. Soufi N, Kohli R. PMID: 29601095; PMCID: PMC6422155.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    29. Bile acid metabolism and signaling: potential therapeutic target for nonalcoholic fatty liver disease. Clin Transl Gastroenterol. 2018 06 29; 9(6):164. Lin CH, Kohli R. PMID: 29955036; PMCID: PMC6023895.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    30. "Twin" Biliary Trees in a Patient With Heterotaxy Syndrome. J Pediatr Gastroenterol Nutr. 2018 06; 66(6):e158. Kelly D, Johnson N, Veldtman G, Kocoshis S, Kohli R. PMID: 27504813.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids. Hepatology. 2018 02; 67(2):534-548. Puri P, Daita K, Joyce A, Mirshahi F, Santhekadur PK, Cazanave S, Luketic VA, Siddiqui MS, Boyett S, Min HK, Kumar DP, Kohli R, Zhou H, Hylemon PB, Contos MJ, Idowu M, Sanyal AJ. PMID: 28696585; PMCID: PMC5764808.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    32. Response to the Letters Regarding the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition NAFLD Guidelines. J Pediatr Gastroenterol Nutr. 2017 11; 65(5):e115-e116. Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. PMID: 29059122.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Quantitative Liver MRI-Biopsy Correlation in Pediatric and Young Adult Patients With Nonalcoholic Fatty Liver Disease: Can One Be Used to Predict the Other? AJR Am J Roentgenol. 2018 Jan; 210(1):166-174. Dillman JR, Trout AT, Costello EN, Serai SD, Bramlage KS, Kohli R, Xanthakos SA. PMID: 29045180; PMCID: PMC6044727.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    34. Liver transplantation in children: state of the art and future perspectives. Arch Dis Child. 2018 02; 103(2):192-198. Kohli R, Cortes M, Heaton ND, Dhawan A. PMID: 28918383.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. Response to Letters Regarding the NASPGHAN NAFLD Guidelines. J Pediatr Gastroenterol Nutr. 2017 Sep 01. Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. PMID: 28872475.
      View in: PubMed   Mentions:
    36. Increased glycine-amidated hyocholic acid correlates to improved early weight loss after sleeve gastrectomy. Surg Endosc. 2018 02; 32(2):805-812. Kindel TL, Krause C, Helm MC, McBride CL, Oleynikov D, Thakare R, Alamoudi J, Kothari V, Alnouti Y, Kohli R. PMID: 28779240; PMCID: PMC5844265.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis. JCI Insight. 2017 Aug 03; 2(15). Tomita K, Kohli R, MacLaurin BL, Hirsova P, Guo Q, Sanchez LHG, Gelbard HA, Blaxall BC, Ibrahim SH. PMID: 28768902; PMCID: PMC5543922.
      View in: PubMed   Mentions: 13     Fields:    
    38. Hepatic Natural Killer T-cell and CD8+ T-cell Signatures in Mice with Nonalcoholic Steatohepatitis. Hepatol Commun. 2017 Jun; 1(4):299-310. Bhattacharjee J, Kirby M, Softic S, Miles L, Salazar-Gonzalez RM, Shivakumar P, Kohli R. PMID: 29152605; PMCID: PMC5687094.
      View in: PubMed   Mentions: 29  
    39. Hepatic Issues and Complications Associated With Inflammatory Bowel Disease: A Clinical Report From the NASPGHAN Inflammatory Bowel Disease and Hepatology Committees. J Pediatr Gastroenterol Nutr. 2017 04; 64(4):639-652. Saubermann LJ, Deneau M, Falcone RA, Murray KF, Ali S, Kohli R, Ekong UD, Valentino PL, Grossman AB, Rand EB, Jonas MM, Saeed SA, Kamath BM. PMID: 27984347.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Impact of Fibroblast Growth Factors 19 and 21 in Bariatric Metabolism. Dig Dis. 2017; 35(3):191-196. Patton A, Khan FH, Kohli R. PMID: 28249286; PMCID: PMC6372241.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    41. NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). J Pediatr Gastroenterol Nutr. 2017 02; 64(2):319-334. Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA. PMID: 28107283; PMCID: PMC5413933.
      View in: PubMed   Mentions: 137     Fields:    Translation:Humans
    42. Treatment of Inferior Vena Cava Obstruction Following Pediatric Liver Transplantation: Novel Use of a Customized Endovascular Stent. J Pediatr. 2017 01; 180:256-260. Averin K, Bucuvalas J, Alonso MH, Kohli R, Heubi JE, Johnson ND, Goldstein BH. PMID: 27793336.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. Alpha 1-antitrypsin levels can differentiate allelic phenotypes. Dig Liver Dis. 2016 Dec; 48(12):1510-1511. Samuel EM, Bernstein K, Xanthakos SA, Kohli R. PMID: 27720697.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Lysosomal Acid Lipase Deficiency Unmasked in Two Children With Nonalcoholic Fatty Liver Disease. Pediatrics. 2016 10; 138(4). Himes RW, Barlow SE, Bove K, Quintanilla NM, Sheridan R, Kohli R. PMID: 27624512.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Fibroblast growth factor 21 correlates with weight loss after vertical sleeve gastrectomy in adolescents. Obesity (Silver Spring). 2016 11; 24(11):2377-2383. Khan FH, Shaw L, Zhang W, Salazar Gonzalez RM, Mowery S, Oehrle M, Zhao X, Jenkins T, Setchell KD, Inge TH, Kohli R. PMID: 27615057; PMCID: PMC5846337.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    46. In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores. Gastroenterology. 2016 12; 151(6):1141-1154.e9. Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van Natta ML, Clark JM, Tonascia J, Doo E, NASH CRN. PMID: 27569726; PMCID: PMC5124386.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    47. Prospective Assessment of Correlation between US Acoustic Radiation Force Impulse and MR Elastography in a Pediatric Population: Dispersion of US Shear-Wave Speed Measurement Matters. Radiology. 2016 Nov; 281(2):544-552. Trout AT, Dillman JR, Xanthakos S, Kohli R, Sprague G, Serai S, Mahley AD, Podberesky DJ. PMID: 27228332.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    48. Pediatric Nonalcoholic Fatty Liver Disease: A Report from the Expert Committee on Nonalcoholic Fatty Liver Disease (ECON). J Pediatr. 2016 05; 172:9-13. Kohli R, Sunduram S, Mouzaki M, Ali S, Sathya P, Abrams S, Xanthakos SA, Vos M, Schwimmer JB. PMID: 26749112; PMCID: PMC4846502.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    49. Bariatric Surgery: The Rise and Fall of Bile Acids. Surg Obes Relat Dis. 2016 05; 12(4):770-771. Khan FH, Kohli R. PMID: 26965154.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    50. Let the bile flow! Hepatology. 2015 Dec; 62(6):1870. Kohli R, Setchell KD. PMID: 26391103; PMCID: PMC4681672.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    51. Familial homozygous hypercholesterolemia: When to turn to transplant? Pediatr Transplant. 2015 Sep; 19(6):577-9. Asai A, Kohli R. PMID: 26215795.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    52. Bile Acid Signaling: Mechanism for Bariatric Surgery, Cure for NASH? Dig Dis. 2015; 33(3):440-6. Kohli R, Myronovych A, Tan BK, Salazar-Gonzalez RM, Miles L, Zhang W, Oehrle M, Sandoval DA, Ryan KK, Seeley RJ, Setchell KD. PMID: 26045281; PMCID: PMC6062006.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    53. Neurologic outcome of urea cycle disorder liver transplant recipients may be predicted by pretransplant neurological imaging. Pediatr Transplant. 2015 Aug; 19(5):527-30. Bolton SM, Campbell KM, Kukreja M, Kohli R. PMID: 25968590; PMCID: PMC4485533.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    54. Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2015 Mar; 60(3):360-7. Corey KE, Vuppalanchi R, Vos M, Kohli R, Molleston JP, Wilson L, Unalp-Arida A, Cummings OW, Lavine JE, Chalasani N, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 25714579; PMCID: PMC4341955.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    55. The evaluation of hepatic fibrosis scores in children with nonalcoholic fatty liver disease. Dig Dis Sci. 2015 May; 60(5):1440-7. Mansoor S, Yerian L, Kohli R, Xanthakos S, Angulo P, Ling S, Lopez R, Christine CK, Feldstein AE, Alkhouri N. PMID: 25540086.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    56. The role of small heterodimer partner in nonalcoholic fatty liver disease improvement after sleeve gastrectomy in mice. Obesity (Silver Spring). 2014 Nov; 22(11):2301-11. Myronovych A, Salazar-Gonzalez RM, Ryan KK, Miles L, Zhang W, Jha P, Wang L, Setchell KD, Seeley RJ, Kohli R. PMID: 25376397; PMCID: PMC4286402.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    57. NHE1 deficiency in liver: implications for non-alcoholic fatty liver disease. Biochem Biophys Res Commun. 2014 Jul 25; 450(2):1027-31. Prasad V, Chirra S, Kohli R, Shull GE. PMID: 24976401; PMCID: PMC4111981.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    58. Effect of guanylate cyclase-C activity on energy and glucose homeostasis. Diabetes. 2014 Nov; 63(11):3798-804. Begg DP, Steinbrecher KA, Mul JD, Chambers AP, Kohli R, Haller A, Cohen MB, Woods SC, Seeley RJ. PMID: 24898144; PMCID: PMC4207398.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    59. High prevalence of hepatitis B non-immunity in paediatric non-alcoholic fatty liver disease patients. Dig Liver Dis. 2014 Aug; 46(8):760-1. Mehta M, Slaughter C, Xanthakos SA, Kohli R. PMID: 24742537; PMCID: PMC4300100.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    60. IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. Hepatology. 2014 May; 59(5):1830-9. Harley IT, Stankiewicz TE, Giles DA, Softic S, Flick LM, Cappelletti M, Sheridan R, Xanthakos SA, Steinbrecher KA, Sartor RB, Kohli R, Karp CL, Divanovic S. PMID: 24115079; PMCID: PMC3975735.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    61. FXR is a molecular target for the effects of vertical sleeve gastrectomy. Nature. 2014 May 08; 509(7499):183-8. Ryan KK, Tremaroli V, Clemmensen C, Kovatcheva-Datchary P, Myronovych A, Karns R, Wilson-Pérez HE, Sandoval DA, Kohli R, Bäckhed F, Seeley RJ. PMID: 24670636; PMCID: PMC4016120.
      View in: PubMed   Mentions: 341     Fields:    Translation:AnimalsCells
    62. There's more under the nonalcoholic fatty liver disease umbrella than an elevated alanine aminotransferase level. J Pediatr. 2014 Apr; 164(4):684-6. Kohli R. PMID: 24461787.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    63. Mixed lineage kinase 3 deficient mice are protected against the high fat high carbohydrate diet-induced steatohepatitis. Liver Int. 2014 Mar; 34(3):427-37. Ibrahim SH, Gores GJ, Hirsova P, Kirby M, Miles L, Jaeschke A, Kohli R. PMID: 24256559; PMCID: PMC3977027.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    64. Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia. Gut. 2014 Aug; 63(8):1238-46. Habegger KM, Al-Massadi O, Heppner KM, Myronovych A, Holland J, Berger J, Yi CX, Gao Y, Lehti M, Ottaway N, Amburgy S, Raver C, Müller TD, Pfluger PT, Kohli R, Perez-Tilve D, Seeley RJ, Tschöp MH. PMID: 24107591; PMCID: PMC3981953.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    65. Use of magnetic resonance elastography to assess hepatic fibrosis in children with chronic liver disease. J Pediatr. 2014 Jan; 164(1):186-8. Xanthakos SA, Podberesky DJ, Serai SD, Miles L, King EC, Balistreri WF, Kohli R. PMID: 24064151; PMCID: PMC3872246.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    66. Vertical sleeve gastrectomy reduces hepatic steatosis while increasing serum bile acids in a weight-loss-independent manner. Obesity (Silver Spring). 2014 Feb; 22(2):390-400. Myronovych A, Kirby M, Ryan KK, Zhang W, Jha P, Setchell KD, Dexheimer PJ, Aronow B, Seeley RJ, Kohli R. PMID: 23804416; PMCID: PMC3836901.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    67. Diabetes: the search for mechanisms underlying bariatric surgery. Nat Rev Endocrinol. 2013 Oct; 9(10):572-4. Kohli R, Seeley RJ. PMID: 23959364; PMCID: PMC3925888.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    68. MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet. Am J Physiol Endocrinol Metab. 2013 Aug 15; 305(4):E549-56. Gadang V, Kohli R, Myronovych A, Hui DY, Perez-Tilve D, Jaeschke A. PMID: 23860122; PMCID: PMC3891220.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    69. A multidisciplinary clinical program is effective in stabilizing BMI and reducing transaminase levels in pediatric patients with NAFLD. J Pediatr Gastroenterol Nutr. 2013 Jul; 57(1):119-23. DeVore S, Kohli R, Lake K, Nicholas L, Dietrich K, Balistreri WF, Xanthakos SA. PMID: 23518484; PMCID: PMC3696482.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    70. A surgical model in male obese rats uncovers protective effects of bile acids post-bariatric surgery. Endocrinology. 2013 Jul; 154(7):2341-51. Kohli R, Setchell KD, Kirby M, Myronovych A, Ryan KK, Ibrahim SH, Berger J, Smith K, Toure M, Woods SC, Seeley RJ. PMID: 23592746; PMCID: PMC3689286.
      View in: PubMed   Mentions: 57     Fields:    Translation:Animals
    71. Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids. J Clin Endocrinol Metab. 2013 Apr; 98(4):E708-12. Kohli R, Bradley D, Setchell KD, Eagon JC, Abumrad N, Klein S. PMID: 23457410; PMCID: PMC3615197.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCellsCTClinical Trials
    72. An adolescent girl with belly pain: one gallbladder too many? J Pediatr Gastroenterol Nutr. 2012 Dec; 55(6):e142. Minar P, Alonso MH, Smith MT, Kohli R. PMID: 22331016; PMCID: PMC3369008.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Fibroblast growth factor-19 action in the brain reduces food intake and body weight and improves glucose tolerance in male rats. Endocrinology. 2013 Jan; 154(1):9-15. Ryan KK, Kohli R, Gutierrez-Aguilar R, Gaitonde SG, Woods SC, Seeley RJ. PMID: 23183168; PMCID: PMC3529386.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimals
    74. Advances in the surgical treatment of morbid obesity. Mol Aspects Med. 2013 Feb; 34(1):84-94. Stefater MA, Kohli R, Inge TH. PMID: 23089054.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    75. Pediatric nonalcoholic fatty liver disease: Prevalence, diagnosis, risk factors, and management. Clin Liver Dis (Hoboken). 2012 Sep; 1(4):125-128. Xanthakos SA, Kohli R. PMID: 31186868; PMCID: PMC6499281.
      View in: PubMed   Mentions:
    76. Isolated unilateral cytomegalovirus retinitis: a rare long-term complication after pediatric liver transplantation. Pediatr Transplant. 2013 Feb; 17(1):E16-9. Squires JE, Sisk RA, Balistreri WF, Kohli R. PMID: 22738313; PMCID: PMC3461246.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    77. Treating pediatric nonalcoholic fatty liver disease with cysteamine: is adiponectin the key? J Pediatr. 2012 Oct; 161(4):579-81. Xanthakos SA, Kohli R. PMID: 22738945.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    78. Fatty liver disease in children--what should one do? Indian J Pediatr. 2013 Mar; 80 Suppl 1:S109-14. Bramlage KS, Bansal V, Xanthakos SA, Kohli R. PMID: 22722986.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    79. Insulin concentration modulates hepatic lipid accumulation in mice in part via transcriptional regulation of fatty acid transport proteins. PLoS One. 2012; 7(6):e38952. Softic S, Kirby M, Berger NG, Shroyer NF, Woods SC, Kohli R. PMID: 22745692; PMCID: PMC3380053.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    80. Retrospective review of the incidence of cytomegalovirus infection and disease after liver transplantation in pediatric patients: comparison of prophylactic oral ganciclovir and oral valganciclovir. Liver Transpl. 2012 Mar; 18(3):347-54. Bedel AN, Hemmelgarn TS, Kohli R. PMID: 22139888; PMCID: PMC3288748.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    81. Molecular insights from bariatric surgery. Rev Endocr Metab Disord. 2011 Sep; 12(3):211-7. Kohli R, Stefater MA, Inge TH. PMID: 21331643; PMCID: PMC4297359.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    82. Mechanisms of lipotoxicity in NAFLD and clinical implications. J Pediatr Gastroenterol Nutr. 2011 Aug; 53(2):131-40. Ibrahim SH, Kohli R, Gores GJ. PMID: 21629127; PMCID: PMC3145329.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimals
    83. The role of the gut hormone GLP-1 in the metabolic improvements caused by ileal transposition. J Surg Res. 2012 Nov; 178(1):33-9. Gaitonde S, Kohli R, Seeley R. PMID: 22929182; PMCID: PMC3479323.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    84. NASH animal models: are we there yet? J Hepatol. 2011 Oct; 55(4):941-3. Kohli R, Feldstein AE. PMID: 21708199.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    85. Relations of steatosis type, grade, and zonality to histological features in pediatric nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):190-7. Carter-Kent C, Brunt EM, Yerian LM, Alkhouri N, Angulo P, Kohli R, Ling SC, Xanthakos SA, Whitington PF, Charatcharoenwitthaya P, Yap J, Lopez R, McCullough AJ, Feldstein AE. PMID: 21240012.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    86. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology. 2010 Sep; 52(3):934-44. Kohli R, Kirby M, Xanthakos SA, Softic S, Feldstein AE, Saxena V, Tang PH, Miles L, Miles MV, Balistreri WF, Woods SC, Seeley RJ. PMID: 20607689; PMCID: PMC2932817.
      View in: PubMed   Mentions: 134     Fields:    Translation:Animals
    87. Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3):G652-60. Kohli R, Kirby M, Setchell KD, Jha P, Klustaitis K, Woollett LA, Pfluger PT, Balistreri WF, Tso P, Jandacek RJ, Woods SC, Heubi JE, Tschoep MH, D'Alessio DA, Shroyer NF, Seeley RJ. PMID: 20595624; PMCID: PMC2950688.
      View in: PubMed   Mentions: 78     Fields:    Translation:Animals
    88. Rapid progression of NASH in childhood. J Pediatr Gastroenterol Nutr. 2010 Apr; 50(4):453-6. Kohli R, Boyd T, Lake K, Dietrich K, Nicholas L, Balistreri WF, Ebach D, Shashidhar H, Xanthakos SA. PMID: 20179647; PMCID: PMC2880161.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    89. Nonalcoholic steatohepatitis in children: a multicenter clinicopathological study. Hepatology. 2009 Oct; 50(4):1113-20. Carter-Kent C, Yerian LM, Brunt EM, Angulo P, Kohli R, Ling SC, Xanthakos SA, Whitington PF, Charatcharoenwitthaya P, Yap J, Lopez R, McCullough AJ, Feldstein AE. PMID: 19637190; PMCID: PMC2775705.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    90. Mitochondrial reactive oxygen species signal hepatocyte steatosis by regulating the phosphatidylinositol 3-kinase cell survival pathway. J Biol Chem. 2007 Jul 20; 282(29):21327-36. Kohli R, Pan X, Malladi P, Wainwright MS, Whitington PF. PMID: 17540768.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    91. Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium. Am J Physiol Gastrointest Liver Physiol. 2006 Jul; 291(1):G55-62. Sahai A, Pan X, Paul R, Malladi P, Kohli R, Whitington PF. PMID: 16439472.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    92. Carnitine treatment inhibits increases in cerebral carnitine esters and glutamate detected by mass spectrometry after hypoxia-ischemia in newborn rats. Stroke. 2006 Feb; 37(2):524-30. Wainwright MS, Kohli R, Whitington PF, Chace DH. PMID: 16385097.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    93. Mesalamine-induced pneumonitis during therapy for chronic inflammatory bowel disease: a pediatric case report. J Pediatr Gastroenterol Nutr. 2005 Oct; 41(4):479-82. Kohli R, Melin-Aldana H, Sentongo TA. PMID: 16205520.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    94. Relative elevations of serum alanine and aspartate aminotransferase in muscular dystrophy. J Pediatr Gastroenterol Nutr. 2005 Jul; 41(1):121-4. Kohli R, Harris DC, Whitington PF. PMID: 15990642.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    95. Differential diagnosis of recurrent abdominal pain: new considerations. Pediatr Ann. 2004 Feb; 33(2):113-22. Kohli R, Li BU. PMID: 14999944.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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