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Effect of Hormone Therapy on Lipoprotein Subfractions in Early and Late Postmenopausal Women. J Clin Endocrinol Metab. 2024 Mar 28.
Sriprasert I, Kim SS, Mohammed IE, Kono N, Karim R, Allayee H, Hodis HN, Mack WJ, Krauss RM. PMID: 38547457.
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PubMed Mentions: Fields:
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Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort. Metabolites. 2024 Mar 20; 14(3).
Mirzaei S, DeVon HA, Cantor RM, Cupido AJ, Pan C, Ha SM, Silva LF, Hilser JR, Hartiala J, Allayee H, Rey FE, Laakso M, Lusis AJ. PMID: 38535334; PMCID: PMC10972019.
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PubMed Mentions:
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Publisher Correction: A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Nat Med. 2024 Mar 06.
Ferrell M, Wang Z, Anderson JT, Li XS, Witkowski M, DiDonato JA, Hilser JR, Hartiala JA, Haghikia A, Cajka T, Fiehn O, Sangwan N, Demuth I, König M, Steinhagen-Thiessen E, Landmesser U, Tang WHW, Allayee H, Hazen SL. PMID: 38448791.
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PubMed Mentions: Fields:
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A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Nat Med. 2024 Feb; 30(2):424-434.
Ferrell M, Wang Z, Anderson JT, Li XS, Witkowski M, DiDonato JA, Hilser JR, Hartiala JA, Haghikia A, Cajka T, Fiehn O, Sangwan N, Demuth I, König M, Steinhagen-Thiessen E, Landmesser U, Tang WHW, Allayee H, Hazen SL. PMID: 38374343.
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Translation:
HumansAnimals
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Genetics unravels protein-metabolite relationships. Trends Endocrinol Metab. 2024 03; 35(3):183-184.
Hilser JR, Lusis AJ, Allayee H. PMID: 38302401; PMCID: PMC10939837.
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PubMed Mentions: Fields:
Translation:
Humans
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Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction. Circ Res. 2024 02 16; 134(4):371-389.
Wang YC, Koay YC, Pan C, Zhou Z, Tang W, Wilcox J, Li XS, Zagouras A, Marques F, Allayee H, Rey FE, Kaye DM, O'Sullivan JF, Hazen SL, Cao Y, Lusis AJ. PMID: 38264909; PMCID: PMC10923103.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivity. J Allergy Clin Immunol. 2024 Jan 19.
Sakano Y, Sakano K, Hurrell BP, Helou DG, Shafiei-Jahani P, Kazemi MH, Li X, Shen S, Hilser JR, Hartiala JA, Allayee H, Barbers R, Akbari O. PMID: 38244725.
View in:
PubMed Mentions: Fields:
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Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and Mice. medRxiv. 2023 Dec 11.
Biswas S, Hilser JR, Woodward NC, Wang Z, Gukasyan J, Nemet I, Schwartzman WS, Huang P, Han Y, Fouladian Z, Charugundla S, Spencer NJ, Pan C, Tang WHW, Lusis AJ, Hazen SL, Hartiala JA, Allayee H. PMID: 38168321; PMCID: PMC10760269.
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PubMed Mentions:
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Systems genetics approaches for understanding complex traits with relevance for human disease. Elife. 2023 11 14; 12.
Allayee H, Farber CR, Seldin MM, Williams EG, James DE, Lusis AJ. PMID: 37962168; PMCID: PMC10645424.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Effects of Dietary Sugar Reduction on Biomarkers of Cardiometabolic Health in Latino Youth: Secondary Analyses from a Randomized Controlled Trial. Nutrients. 2023 Jul 27; 15(15).
Schmidt KA, Mokhtari P, Holzhausen EA, Alderete TL, Allayee H, Nayak KS, Sinatra FR, Pickering TA, Mack W, Kohli R, Goran MI. PMID: 37571275; PMCID: PMC10420969.
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PubMed Mentions: Fields:
Translation:
Humans
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Trimethylamine N-Oxide Response to a Mixed Macronutrient Tolerance Test in a Cohort of Healthy United States Adults. Int J Mol Sci. 2023 Jan 20; 24(3).
James KL, Gertz ER, Kirschke CP, Allayee H, Huang L, Kable ME, Newman JW, Stephensen CB, Bennett BJ. PMID: 36768394; PMCID: PMC9917175.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure. Science. 2022 09 23; 377(6613):1399-1406.
Cao Y, Wang Y, Zhou Z, Pan C, Jiang L, Zhou Z, Meng Y, Charugundla S, Li T, Allayee H, Seldin MM, Lusis AJ. PMID: 36137043; PMCID: PMC9639660.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach. Mol Metab. 2022 10; 64:101557.
Cao Y, Aquino-Martinez R, Hutchison E, Allayee H, Lusis AJ, Rey FE. PMID: 35870705; PMCID: PMC9399267.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women. Clin Epigenetics. 2022 07 18; 14(1):90.
Hilser JR, Hartiala JA, Sriprasert I, Kono N, Cai Z, Karim R, DeYoung J, Mack WJ, Hodis HN, Allayee H. PMID: 35850911; PMCID: PMC9295504.
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Translation:
HumansCells
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Clinical Intervention to Reduce Dietary Sugar Does Not Affect Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial. J Nutr. 2022 07 06; 152(7):1655-1665.
Schmidt KA, Jones RB, Rios C, Corona Y, Berger PK, Plows JF, Alderete TL, Fogel J, Hampson H, Hartiala JA, Cai Z, Allayee H, Nayak KS, Sinatra FR, Harlan G, Pickering TA, Salvy SJ, Mack WJ, Kohli R, Goran MI. PMID: 35218194; PMCID: PMC9258557.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis. Front Physiol. 2022; 13:909870.
Schillemans T, Tragante V, Maitusong B, Gigante B, Cresci S, Laguzzi F, Vikström M, Richards M, Pilbrow A, Cameron V, Foco L, Doughty RN, Kuukasjärvi P, Allayee H, Hartiala JA, Tang WHW, Lyytikäinen LP, Nikus K, Laurikka JO, Srinivasan S, Mordi IR, Trompet S, Kraaijeveld A, van Setten J, Gijsberts CM, Maitland-van der Zee AH, Saely CH, Gong Y, Johnson JA, Cooper-DeHoff RM, Pepine CJ, Casu G, Leiherer A, Drexel H, Horne BD, van der Laan SW, Marziliano N, Hazen SL, Sinisalo J, Kähönen M, Lehtimäki T, Lang CC, Burkhardt R, Scholz M, Jukema JW, Eriksson N, Åkerblom A, James S, Held C, Hagström E, Spertus JA, Algra A, de Faire U, Åkesson A, Asselbergs FW, Patel RS, Leander K. PMID: 35812313; PMCID: PMC9260705.
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Near-roadway air pollution, immune cells and adipokines among obese young adults. Environ Health. 2022 03 19; 21(1):36.
Rahman MM, Liu FF, Eckel SP, Sankaranarayanan I, Shafiei-Jahani P, Howard E, Baronikian L, Sattler F, Lurmann FW, Allayee H, Akbari O, McConnell R. PMID: 35305663; PMCID: PMC8933931.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Gene-Environment Interactions for Cardiovascular Disease. Curr Atheroscler Rep. 2021 10 14; 23(12):75.
Hartiala JA, Hilser JR, Biswas S, Lusis AJ, Allayee H. PMID: 34648097; PMCID: PMC8903169.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population. Elife. 2021 09 29; 10.
Garcia AR, Finch C, Gatz M, Kraft T, Eid Rodriguez D, Cummings D, Charifson M, Buetow K, Beheim BA, Allayee H, Thomas GS, Stieglitz J, Gurven MD, Kaplan H, Trumble BC. PMID: 34586066; PMCID: PMC8480980.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
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Noise Exposure and Distortion Product Otoacoustic Emission Suprathreshold Amplitudes: A Genome-Wide Association Study. Audiol Neurootol. 2021; 26(6):445-453.
Lavinsky J, Kasperbauer G, Bento RF, Mendonça A, Wang J, Crow AL, Allayee H, Friedman RA. PMID: 34280920; PMCID: PMC8612944.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsPHPublic Health
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PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity. Nutrients. 2021 May 12; 13(5).
Jones RB, Arenaza L, Rios C, Plows JF, Berger PK, Alderete TL, Fogel JL, Nayak K, Mohamed P, Hwang D, Palmer S, Sinatra F, Allayee H, Kohli R, Goran MI. PMID: 34065978; PMCID: PMC8151324.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur Heart J. 2021 05 07; 42(18):1742-1756.
Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee H, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James SK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Koenig W, Fliser D, Laufs U, Speer T, eQTLGen consortium, BIOS consortium. PMID: 33748830; PMCID: PMC8244638.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation. Mucosal Immunol. 2021 07; 14(4):899-911.
Shafiei-Jahani P, Helou DG, Hurrell BP, Galle-Treger L, Howard E, Quach C, Painter JD, Fung M, Lo R, Allayee H, Akbari O. PMID: 33731828; PMCID: PMC8225558.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Genetic evidence for independent causal relationships between metabolic biomarkers and risk of coronary artery diseases. J Lipid Res. 2021; 62:100064.
Allayee H. PMID: 33705740; PMCID: PMC8058558.
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PubMed Mentions:
1 Fields:
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Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection. J Lipid Res. 2021; 62:100061.
Hilser JR, Han Y, Biswas S, Gukasyan J, Cai Z, Zhu R, Tang WHW, Deb A, Lusis AJ, Hartiala JA, Allayee H. PMID: 33667465; PMCID: PMC7923911.
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PubMed Mentions:
25 Fields:
Translation:
HumansCells
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Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. Eur Heart J. 2021 03 01; 42(9):919-933.
Hartiala JA, Han Y, Jia Q, Hilser JR, Huang P, Gukasyan J, Schwartzman WS, Cai Z, Biswas S, Trégouët DA, Smith NL, INVENT Consortium, CHARGE Consortium Hemostasis Working Group, GENIUS-CHD Consortium, Seldin M, Pan C, Mehrabian M, Lusis AJ, Bazeley P, Sun YV, Liu C, Quyyumi AA, Scholz M, Thiery J, Delgado GE, Kleber ME, März W, Howe LJ, Asselbergs FW, van Vugt M, Vlachojannis GJ, Patel RS, Lyytikäinen LP, Kähönen M, Lehtimäki T, Nieminen TVM, Kuukasjärvi P, Laurikka JO, Chang X, Heng CK, Jiang R, Kraus WE, Hauser ER, Ferguson JF, Reilly MP, Ito K, Koyama S, Kamatani Y, Komuro I, Biobank Japan, Stolze LK, Romanoski CE, Khan MD, Turner AW, Miller CL, Aherrahrou R, Civelek M, Ma L, Björkegren JLM, Kumar SR, Tang WHW, Hazen SL, Allayee H. PMID: 33532862; PMCID: PMC7936531.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression. Metabolism. 2021 03; 116:154457.
Nimer N, Choucair I, Wang Z, Nemet I, Li L, Gukasyan J, Weeks TL, Alkhouri N, Zein N, Tang WHW, Fischbach MA, Brown JM, Allayee H, Dasarathy S, Gogonea V, Hazen SL. PMID: 33275980; PMCID: PMC7856026.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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The Genetics of Variation of the Wave 1 Amplitude of the Mouse Auditory Brainstem Response. J Assoc Res Otolaryngol. 2020 08; 21(4):323-336.
Boussaty EC, Gillard D, Lavinsky J, Salehi P, Wang J, Mendonça A, Allayee H, Manor U, Friedman RA. PMID: 32757112; PMCID: PMC7445221.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCellsPHPublic Health
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Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data. Circulation. 2020 08 11; 142(6):546-555.
Mahmoodi BK, Tragante V, Kleber ME, Holmes MV, Schmidt AF, McCubrey RO, Howe LJ, Direk K, Allayee H, Baranova EV, Braund PS, Delgado GE, Eriksson N, Gijsberts CM, Gong Y, Hartiala J, Heydarpour M, Pasterkamp G, Kotti S, Kuukasjärvi P, Lenzini PA, Levin D, Lyytikäinen LP, Muehlschlegel JD, Nelson CP, Nikus K, Pilbrow AP, Wilson Tang WH, van der Laan SW, van Setten J, Vilmundarson RO, Deanfield J, Deloukas P, Dudbridge F, James S, Mordi IR, Teren A, Bergmeijer TO, Body SC, Bots M, Burkhardt R, Cooper-DeHoff RM, Cresci S, Danchin N, Doughty RN, Grobbee DE, Hagström E, Hazen SL, Held C, Hoefer IE, Hovingh GK, Johnson JA, Kaczor MP, Kähönen M, Klungel OH, Laurikka JO, Lehtimäki T, Maitland-van der Zee AH, McPherson R, Palmer CN, Kraaijeveld AO, Pepine CJ, Sanak M, Sattar N, Scholz M, Simon T, Spertus JA, Stewart AFR, Szczeklik W, Thiery J, Visseren FLJ, Waltenberger J, Richards AM, Lang CC, Cameron VA, Åkerblom A, Pare G, März W, Samani NJ, Hingorani AD, Ten Berg JM, Wallentin L, Asselbergs FW, Patel RS. PMID: 32654539; PMCID: PMC7493828.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity. Transl Psychiatry. 2020 07 07; 10(1):218.
Haghani A, Johnson RG, Woodward NC, Feinberg JI, Lewis K, Ladd-Acosta C, Safi N, Jaffe AE, Sioutas C, Allayee H, Campbell DB, Volk HE, Finch CE, Morgan TE. PMID: 32636363; PMCID: PMC7341755.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCellsPHPublic Health
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Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice. G3 (Bethesda). 2020 07 07; 10(7):2529-2541.
Huda MN, VerHague M, Albright J, Smallwood T, Bell TA, Que E, Miller DR, Roshanravan B, Allayee H, Manuel de Villena FP, Bennett BJ. PMID: 32467129; PMCID: PMC7341122.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
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Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma. Nat Commun. 2020 04 15; 11(1):1776.
Han Y, Jia Q, Jahani PS, Hurrell BP, Pan C, Huang P, Gukasyan J, Woodward NC, Eskin E, Gilliland FD, Akbari O, Hartiala JA, Allayee H. PMID: 32296059; PMCID: PMC7160128.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Toxicity of urban air pollution particulate matter in developing and adult mouse brain: Comparison of total and filter-eluted nanoparticles. Environ Int. 2020 03; 136:105510.
Haghani A, Johnson R, Safi N, Zhang H, Thorwald M, Mousavi A, Woodward NC, Shirmohammadi F, Coussa V, Wise JP, Forman HJ, Sioutas C, Allayee H, Morgan TE, Finch CE. PMID: 32004873; PMCID: PMC7063839.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsPHPublic Health
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A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity. PLoS Genet. 2019 12; 15(12):e1008528.
Maazi H, Hartiala JA, Suzuki Y, Crow AL, Shafiei Jahani P, Lam J, Patel N, Rigas D, Han Y, Huang P, Eskin E, Lusis AJ, Gilliland FD, Akbari O, Allayee H. PMID: 31869344; PMCID: PMC6944376.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Effect of ApoE4 Genotype on the Association Between Metabolic Phenotype and Subclinical Atherosclerosis in Postmenopausal Women. Am J Cardiol. 2019 10 01; 124(7):1031-1037.
Sriprasert I, Mack WJ, Hodis HN, Allayee H, Brinton RD, Karim R. PMID: 31362877; PMCID: PMC6744988.
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PubMed Mentions: Fields:
Translation:
Humans
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Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2019 06; 39(6):1045-1054.
Shih DM, Zhu W, Schugar RC, Meng Y, Jia X, Miikeda A, Wang Z, Zieger M, Lee R, Graham M, Allayee H, Cantor RM, Mueller C, Brown JM, Hazen SL, Lusis AJ. PMID: 31070450; PMCID: PMC6531332.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease. J Am Heart Assoc. 2019 05 21; 8(10):e011922.
Jia Q, Han Y, Huang P, Woodward NC, Gukasyan J, Kettunen J, Ala-Korpela M, Anufrieva O, Wang Q, Perola M, Raitakari O, Lehtimäki T, Viikari J, Järvelin MR, Boehnke M, Laakso M, Mohlke KL, Fiehn O, Wang Z, Tang WHW, Hazen SL, Hartiala JA, Allayee H. PMID: 31070104; PMCID: PMC6585317.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events. Circ Genom Precis Med. 2019 04; 12(4):e002471.
Patel RS, Schmidt AF, Tragante V, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A, Leander K, Virani SS, Kaminski KA, Muehlschlegel JD, Dubé MP, Allayee H, Almgren P, Alver M, Baranova EV, Behlouli H, Boeckx B, Braund PS, Breitling LP, Delgado G, Duarte NE, Dufresne L, Eriksson N, Foco L, Gijsberts CM, Gong Y, Hartiala J, Heydarpour M, Hubacek JA, Kleber M, Kofink D, Kuukasjärvi P, Lee VV, Leiherer A, Lenzini PA, Levin D, Lyytikäinen LP, Martinelli N, Mons U, Nelson CP, Nikus K, Pilbrow AP, Ploski R, Sun YV, Tanck MWT, Tang WHW, Trompet S, van der Laan SW, van Setten J, Vilmundarson RO, Viviani Anselmi C, Vlachopoulou E, Boerwinkle E, Briguori C, Carlquist JF, Carruthers KF, Casu G, Deanfield J, Deloukas P, Dudbridge F, Fitzpatrick N, Gigante B, James S, Lokki ML, Lotufo PA, Marziliano N, Mordi IR, Muhlestein JB, Newton Cheh C, Pitha J, Saely CH, Samman-Tahhan A, Sandesara PB, Teren A, Timmis A, Van de Werf F, Wauters E, Wilde AAM, Ford I, Stott DJ, Algra A, Andreassi MG, Ardissino D, Arsenault BJ, Ballantyne CM, Bergmeijer TO, Bezzina CR, Body SC, Bogaty P, de Borst GJ, Brenner H, Burkhardt R, Carpeggiani C, Condorelli G, Cooper-DeHoff RM, Cresci S, de Faire U, Doughty RN, Drexel H, Engert JC, Fox KAA, Girelli D, Hagström E, Hazen SL, Held C, Hemingway H, Hoefer IE, Hovingh GK, Johnson JA, de Jong PA, Jukema JW, Kaczor MP, Kähönen M, Kettner J, Kiliszek M, Klungel OH, Lagerqvist B, Lambrechts D, Laurikka JO, Lehtimäki T, Lindholm D, Mahmoodi BK, Maitland-van der Zee AH, McPherson R, Melander O, Metspalu A, Pepinski W, Olivieri O, Opolski G, Palmer CN, Pasterkamp G, Pepine CJ, Pereira AC, Pilote L, Quyyumi AA, Richards AM, Sanak M, Scholz M, Siegbahn A, Sinisalo J, Smith JG, Spertus JA, Stewart AFR, Szczeklik W, Szpakowicz A, Ten Berg JM, Thanassoulis G, Thiery J, van der Graaf Y, Visseren FLJ, Waltenberger J, CARDIoGRAMPlusC4D Consortium, Van der Harst P, Tardif JC, Sattar N, Lang CC, Pare G, Brophy JM, Anderson JL, März W, Wallentin L, Cameron VA, Horne BD, Samani NJ, Hingorani AD, Asselbergs FW. PMID: 30897348; PMCID: PMC6625876.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Subsequent Event Risk in Individuals With Established Coronary Heart Disease. Circ Genom Precis Med. 2019 04; 12(4):e002470.
Patel RS, Tragante V, Schmidt AF, McCubrey RO, Holmes MV, Howe LJ, Direk K, Åkerblom A, Leander K, Virani SS, Kaminski KA, Muehlschlegel JD, Allayee H, Almgren P, Alver M, Baranova EV, Behloui H, Boeckx B, Braund PS, Breitling LP, Delgado G, Duarte NE, Dubé MP, Dufresne L, Eriksson N, Foco L, Scholz M, Gijsberts CM, Glinge C, Gong Y, Hartiala J, Heydarpour M, Hubacek JA, Kleber M, Kofink D, Kotti S, Kuukasjärvi P, Lee VV, Leiherer A, Lenzini PA, Levin D, Lyytikäinen LP, Martinelli N, Mons U, Nelson CP, Nikus K, Pilbrow AP, Ploski R, Sun YV, Tanck MWT, Tang WHW, Trompet S, van der Laan SW, Van Setten J, Vilmundarson RO, Viviani Anselmi C, Vlachopoulou E, Al Ali L, Boerwinkle E, Briguori C, Carlquist JF, Carruthers KF, Casu G, Deanfield J, Deloukas P, Dudbridge F, Engstrøm T, Fitzpatrick N, Fox K, Gigante B, James S, Lokki ML, Lotufo PA, Marziliano N, Mordi IR, Muhlestein JB, Newton-Cheh C, Pitha J, Saely CH, Samman-Tahhan A, Sandesara PB, Teren A, Timmis A, Van de Werf F, Wauters E, Wilde AAM, Ford I, Stott DJ, Algra A, Andreassi MG, Ardissino D, Arsenault BJ, Ballantyne CM, Bergmeijer TO, Bezzina CR, Body SC, Boersma EH, Bogaty P, Bots ML, Brenner H, Brugts JJ, Burkhardt R, Carpeggiani C, Condorelli G, Cooper-DeHoff RM, Cresci S, Danchin N, de Faire U, Doughty RN, Drexel H, Engert JC, Fox KAA, Girelli D, Grobbee DE, Hagström E, Hazen SL, Held C, Hemingway H, Hoefer IE, Hovingh GK, Jabbari R, Johnson JA, Jukema JW, Kaczor MP, Kähönen M, Kettner J, Kiliszek M, Klungel OH, Lagerqvist B, Lambrechts D, Laurikka JO, Lehtimäki T, Lindholm D, Mahmoodi BK, Maitland-van der Zee AH, McPherson R, Melander O, Metspalu A, Niemcunowicz-Janica A, Olivieri O, Opolski G, Palmer CN, Pasterkamp G, Pepine CJ, Pereira AC, Pilote L, Quyyumi AA, Richards AM, Sanak M, Siegbahn A, Simon T, Sinisalo J, Smith JG, Spertus JA, Stender S, Stewart AFR, Szczeklik W, Szpakowicz A, Tardif JC, Ten Berg JM, Tfelt-Hansen J, Thanassoulis G, Thiery J, Torp-Pedersen C, van der Graaf Y, Visseren FLJ, Waltenberger J, Weeke PE, Van der Harst P, Lang CC, Sattar N, Cameron VA, Anderson JL, Brophy JM, Pare G, Horne BD, März W, Wallentin L, Samani NJ, Hingorani AD, Asselbergs FW. PMID: 30896328; PMCID: PMC6629546.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
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Exposure to Nanoscale Particulate Matter from Gestation to Adulthood Impairs Metabolic Homeostasis in Mice. Sci Rep. 2019 02 12; 9(1):1816.
Woodward NC, Crow AL, Zhang Y, Epstein S, Hartiala J, Johnson R, Kocalis H, Saffari A, Sankaranarayanan I, Akbari O, Ramanathan G, Araujo JA, Finch CE, Bouret SG, Sioutas C, Morgan TE, Allayee H. PMID: 30755631; PMCID: PMC6372675.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes. Nat Commun. 2019 02 12; 10(1):713.
Galle-Treger L, Sankaranarayanan I, Hurrell BP, Howard E, Lo R, Maazi H, Lewis G, Banie H, Epstein AL, Hu P, Rehan VK, Gilliland FD, Allayee H, Soroosh P, Sharpe AH, Akbari O. PMID: 30755607; PMCID: PMC6372786.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Apolipoprotein E4 genotype in combination with poor metabolic profile is associated with reduced cognitive performance in healthy postmenopausal women: implications for late onset Alzheimer's disease. Menopause. 2019 01; 26(1):7-15.
Karim R, Koc M, Rettberg JR, Hodis HN, Henderson VW, St John JA, Allayee H, Brinton RD, Mack WJ. PMID: 29975287; PMCID: PMC7508039.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
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Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. JCI Insight. 2018 03 22; 3(6).
Li XS, Wang Z, Cajka T, Buffa JA, Nemet I, Hurd AG, Gu X, Skye SM, Roberts AB, Wu Y, Li L, Shahen CJ, Wagner MA, Hartiala JA, Kerby RL, Romano KA, Han Y, Obeid S, Lüscher TF, Allayee H, Rey FE, DiDonato JA, Fiehn O, Tang WHW, Hazen SL. PMID: 29563342; PMCID: PMC5926943.
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PubMed Mentions:
65 Fields:
Translation:
HumansAnimals
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Proceedings of the 11th Congress of the International Society of Nutrigenetics and Nutrigenomics (ISNN 2017). J Nutrigenet Nutrigenomics. 2017; 10(5-6):155-162.
Barrington WT, Salvador AC, Hartiala JA, De Caterina R, Kohlmeier M, Martinez JA, Kreutzer CB, Heber D, Lusis AJ, Li Z, Allayee H. PMID: 29339647; PMCID: PMC6490176.
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PubMed Mentions: Fields:
Translation:
Humans
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Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. Nat Genet. 2017 Sep; 49(9):1346-1353.
Patterson M, Barske L, Van Handel B, Rau CD, Gan P, Sharma A, Parikh S, Denholtz M, Huang Y, Yamaguchi Y, Shen H, Allayee H, Crump JG, Force TI, Lien CL, Makita T, Lusis AJ, Kumar SR, Sucov HM. PMID: 28783163; PMCID: PMC5736145.
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PubMed Mentions:
164 Fields:
Translation:
AnimalsCells
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Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity. J Nutrigenet Nutrigenomics. 2017; 10(1-2):43-62.
Ramos-Lopez O, Milagro FI, Allayee H, Chmurzynska A, Choi MS, Curi R, De Caterina R, Ferguson LR, Goni L, Kang JX, Kohlmeier M, Marti A, Moreno LA, Pérusse L, Prasad C, Qi L, Reifen R, Riezu-Boj JI, San-Cristobal R, Santos JL, Martínez JA. PMID: 28689206.
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PubMed Mentions:
72 Fields:
Translation:
HumansCellsPHPublic Health
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The in vivo T helper type 17 and regulatory T cell immune responses to Aggregatibacter actinomycetemcomitans. Mol Oral Microbiol. 2017 12; 32(6):490-499.
Mahabady S, Tjokro N, Aharonian S, Zadeh HH, Chen C, Allayee H, Sedghizadeh PP. PMID: 28544588; PMCID: PMC5842142.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Lancet Diabetes Endocrinol. 2017 07; 5(7):534-543.
Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, Direk K, Laufs U, Werner C, Koenig W, Rothenbacher D, Mons U, Breitling LP, Brenner H, Jennings RT, Petrakis I, Triem S, Klug M, Filips A, Blankenberg S, Waldeyer C, Sinning C, Schnabel RB, Lackner KJ, Vlachopoulou E, Nygård O, Svingen GFT, Pedersen ER, Tell GS, Sinisalo J, Nieminen MS, Laaksonen R, Trompet S, Smit RAJ, Sattar N, Jukema JW, Groesdonk HV, Delgado G, Stojakovic T, Pilbrow AP, Cameron VA, Richards AM, Doughty RN, Gong Y, Cooper-DeHoff R, Johnson J, Scholz M, Beutner F, Thiery J, Smith JG, Vilmundarson RO, McPherson R, Stewart AFR, Cresci S, Lenzini PA, Spertus JA, Olivieri O, Girelli D, Martinelli NI, Leiherer A, Saely CH, Drexel H, Mündlein A, Braund PS, Nelson CP, Samani NJ, Kofink D, Hoefer IE, Pasterkamp G, Quyyumi AA, Ko YA, Hartiala JA, Allayee H, Tang WHW, Hazen SL, Eriksson N, Held C, Hagström E, Wallentin L, Åkerblom A, Siegbahn A, Karp I, Labos C, Pilote L, Engert JC, Brophy JM, Thanassoulis G, Bogaty P, Szczeklik W, Kaczor M, Sanak M, Virani SS, Ballantyne CM, Lee VV, Boerwinkle E, Holmes MV, Horne BD, Hingorani A, Asselbergs FW, Patel RS, GENIUS-CHD consortium, Krämer BK, Scharnagl H, Fliser D, März W, Speer T. PMID: 28566218; PMCID: PMC5651679.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. Circulation. 2017 Jun 13; 135(24):2336-2353.
Saleheen D, Zhao W, Young R, Nelson CP, Ho W, Ferguson JF, Rasheed A, Ou K, Nurnberg ST, Bauer RC, Goel A, Do R, Stewart AFR, Hartiala J, Zhang W, Thorleifsson G, Strawbridge RJ, Sinisalo J, Kanoni S, Sedaghat S, Marouli E, Kristiansson K, Hua Zhao J, Scott R, Gauguier D, Shah SH, Smith AV, van Zuydam N, Cox AJ, Willenborg C, Kessler T, Zeng L, Province MA, Ganna A, Lind L, Pedersen NL, White CC, Joensuu A, Edi Kleber M, Hall AS, März W, Salomaa V, O'Donnell C, Ingelsson E, Feitosa MF, Erdmann J, Bowden DW, Palmer CNA, Gudnason V, Faire U, Zalloua P, Wareham N, Thompson JR, Kuulasmaa K, Dedoussis G, Perola M, Dehghan A, Chambers JC, Kooner J, Allayee H, Deloukas P, McPherson R, Stefansson K, Schunkert H, Kathiresan S, Farrall M, Marcel Frossard P, Rader DJ, Samani NJ, Reilly MP. PMID: 28461624; PMCID: PMC5612779.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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The Genetic Architecture of Coronary Artery Disease: Current Knowledge and Future Opportunities. Curr Atheroscler Rep. 2017 Feb; 19(2):6.
Hartiala J, Schwartzman WS, Gabbay J, Ghazalpour A, Bennett BJ, Allayee H. PMID: 28130654; PMCID: PMC5783155.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager-horticulturalists with a high parasite burden. FASEB J. 2017 04; 31(4):1508-1515.
Trumble BC, Stieglitz J, Blackwell AD, Allayee H, Beheim B, Finch CE, Gurven M, Kaplan H. PMID: 28031319; PMCID: PMC5349792.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. G3 (Bethesda). 2016 10 13; 6(10):3219-3228.
Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Salehi P, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA. PMID: 27520957; PMCID: PMC5068943.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. J Assoc Res Otolaryngol. 2016 Oct; 17(5):417-31.
Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI, Allayee H, Lusis AJ, Ohyama T, Friedman RA. PMID: 27539716; PMCID: PMC5023540.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease. Genome Biol. 2016 08 11; 17(1):171.
Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL. PMID: 27511193; PMCID: PMC4980791.
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PubMed Mentions:
311 Fields:
Translation:
HumansCells
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Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation. J Am Heart Assoc. 2016 07 28; 5(8).
Hartiala J, Breton CV, Tang WH, Lurmann F, Hazen SL, Gilliland FD, Allayee H. PMID: 27468926; PMCID: PMC5015312.
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PubMed Mentions:
26 Fields:
Translation:
HumansPHPublic Health
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Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis. Neurology. 2016 Aug 16; 87(7):699-708.
Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. PMID: 27421538; PMCID: PMC4999165.
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PubMed Mentions:
75 Fields:
Translation:
Humans
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Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalized Nutrition: Part 2 - Ethics, Challenges and Endeavors of Precision Nutrition. J Nutrigenet Nutrigenomics. 2016; 9(1):28-46.
Kohlmeier M, De Caterina R, Ferguson LR, Görman U, Allayee H, Prasad C, Kang JX, Nicoletti CF, Martinez JA. PMID: 27286972.
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PubMed Mentions:
26 Fields:
Translation:
HumansPHPublic Health
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Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition. J Nutrigenet Nutrigenomics. 2016; 9(1):12-27.
Ferguson LR, De Caterina R, Görman U, Allayee H, Kohlmeier M, Prasad C, Choi MS, Curi R, de Luis DA, Gil Á, Kang JX, Martin RL, Milagro FI, Nicoletti CF, Nonino CB, Ordovas JM, Parslow VR, Portillo MP, Santos JL, Serhan CN, Simopoulos AP, Velázquez-Arellano A, Zulet MA, Martinez JA. PMID: 27169401.
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PubMed Mentions:
69 Fields:
Translation:
Humans
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Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium. Diabetes. 2016 07; 65(7):2072-80.
Palmer ND, Wagenknecht LE, Langefeld CD, Wang N, Buchanan TA, Xiang AH, Allayee H, Bergman RN, Raffel LJ, Chen YD, Haritunians T, Fingerlin T, Goodarzi MO, Taylor KD, Rotter JI, Watanabe RM, Bowden DW. PMID: 27207554; PMCID: PMC4915581.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Lower omental t-regulatory cell count is associated with higher fasting glucose and lower β-cell function in adults with obesity. Obesity (Silver Spring). 2016 06; 24(6):1274-82.
Gyllenhammer LE, Lam J, Alderete TL, Allayee H, Akbari O, Katkhouda N, Goran MI. PMID: 27133873; PMCID: PMC4882248.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. J Lipid Res. 2016 06; 57(6):925-42.
Lusis AJ, Seldin MM, Allayee H, Bennett BJ, Civelek M, Davis RC, Eskin E, Farber CR, Hui S, Mehrabian M, Norheim F, Pan C, Parks B, Rau CD, Smith DJ, Vallim T, Wang Y, Wang J. PMID: 27099397; PMCID: PMC4878195.
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PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association. Circ Cardiovasc Genet. 2016 Jun; 9(3):291-313.
Ferguson JF, Allayee H, Gerszten RE, Ideraabdullah F, Kris-Etherton PM, Ordovás JM, Rimm EB, Wang TJ, Bennett BJ, American Heart Association Council on Functional Genomics and Translational Biology, Council on Epid. PMID: 27095829; PMCID: PMC7829062.
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PubMed Mentions:
47 Fields:
Translation:
HumansAnimals
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Expanding role of gut microbiota in lipid metabolism. Curr Opin Lipidol. 2016 Apr; 27(2):141-7.
Ghazalpour A, Cespedes I, Bennett BJ, Allayee H. PMID: 26855231; PMCID: PMC5125441.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Choline metabolites: gene by diet interactions. Curr Opin Lipidol. 2016 Feb; 27(1):33-9.
Smallwood T, Allayee H, Bennett BJ. PMID: 26655287; PMCID: PMC4703434.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimals
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Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. Nat Commun. 2016 Jan 29; 7:10558.
Hartiala JA, Tang WH, Wang Z, Crow AL, Stewart AF, Roberts R, McPherson R, Erdmann J, Willenborg C, Hazen SL, Allayee H. PMID: 26822151; PMCID: PMC4740183.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Contribution of Gut Bacteria to Lipid Levels: Another Metabolic Role for Microbes? Circ Res. 2015 Oct 09; 117(9):750-4.
Allayee H, Hazen SL. PMID: 26450886; PMCID: PMC4705836.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nat Genet. 2015 11; 47(11):1282-1293.
Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Leach IM, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, Campanella G, Chadeau-Hyam M, Afzal U, Ahluwalia TS, Bonder MJ, Chen P, Dehghan A, Edwards TL, Esko T, Go MJ, Harris SE, Hartiala J, Kasela S, Kasturiratne A, Khor CC, Kleber ME, Li H, Yu Mok Z, Nakatochi M, Sapari NS, Saxena R, Stewart AFR, Stolk L, Tabara Y, Teh AL, Wu Y, Wu JY, Zhang Y, Aits I, Da Silva Couto Alves A, Das S, Dorajoo R, Hopewell JC, Kim YK, Koivula RW, Luan J, Lyytikäinen LP, Nguyen QN, Pereira MA, Postmus I, Raitakari OT, Scannell Bryan M, Scott RA, Sorice R, Tragante V, Traglia M, White J, Yamamoto K, Zhang Y, Adair LS, Ahmed A, Akiyama K, Asif R, Aung T, Barroso I, Bjonnes A, Braun TR, Cai H, Chang LC, Chen CH, Cheng CY, Chong YS, Collins R, Courtney R, Davies G, Delgado G, Do LD, Doevendans PA, Gansevoort RT, Gao YT, Grammer TB, Grarup N, Grewal J, Gu D, Wander GS, Hartikainen AL, Hazen SL, He J, Heng CK, Hixson JE, Hofman A, Hsu C, Huang W, Husemoen LLN, Hwang JY, Ichihara S, Igase M, Isono M, Justesen JM, Katsuya T, Kibriya MG, Kim YJ, Kishimoto M, Koh WP, Kohara K, Kumari M, Kwek K, Lee NR, Lee J, Liao J, Lieb W, Liewald DCM, Matsubara T, Matsushita Y, Meitinger T, Mihailov E, Milani L, Mills R, Mononen N, Müller-Nurasyid M, Nabika T, Nakashima E, Ng HK, Nikus K, Nutile T, Ohkubo T, Ohnaka K, Parish S, Paternoster L, Peng H, Peters A, Pham ST, Pinidiyapathirage MJ, Rahman M, Rakugi H, Rolandsson O, Ann Rozario M, Ruggiero D, Sala CF, Sarju R, Shimokawa K, Snieder H, Sparsø T, Spiering W, Starr JM, Stott DJ, Stram DO, Sugiyama T, Szymczak S, Tang WHW, Tong L, Trompet S, Turjanmaa V, Ueshima H, Uitterlinden AG, Umemura S, Vaarasmaki M, van Dam RM, van Gilst WH, van Veldhuisen DJ, Viikari JS, Waldenberger M, Wang Y, Wang A, Wilson R, Wong TY, Xiang YB, Yamaguchi S, Ye X, Young RD, Young TL, Yuan JM, Zhou X, Asselbergs FW, Ciullo M, Clarke R, Deloukas P, Franke A, Franks PW, Franks S, Friedlander Y, Gross MD, Guo Z, Hansen T, Jarvelin MR, Jørgensen T, Jukema JW, Kähönen M, Kajio H, Kivimaki M, Lee JY, Lehtimäki T, Linneberg A, Miki T, Pedersen O, Samani NJ, Sørensen TIA, Takayanagi R, Toniolo D, BIOS-consortium, CARDIo GRAMplusCD, LifeLines Cohort Study, InterAct Consortium, Ahsan H, Allayee H, Chen YT, Danesh J, Deary IJ, Franco OH, Franke L, Heijman BT, Holbrook JD, Isaacs A, Kim BJ, Lin X, Liu J, März W, Metspalu A, Mohlke KL, Sanghera DK, Shu XO, van Meurs JBJ, Vithana E, Wickremasinghe AR, Wijmenga C, Wolffenbuttel BHW, Yokota M, Zheng W, Zhu D, Vineis P, Kyrtopoulos SA, Kleinjans JCS, McCarthy MI, Soong R, Gieger C, Scott J, Teo YY, He J, Elliott P, Tai ES, van der Harst P, Kooner JS, Chambers JC. PMID: 26390057; PMCID: PMC4719169.
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PubMed Mentions:
180 Fields:
Translation:
HumansCells
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The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants. G3 (Bethesda). 2015 Sep 04; 5(11):2329-39.
Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA. PMID: 26342000; PMCID: PMC4632053.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study. Early Hum Dev. 2015 Aug; 91(8):483-9.
Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Sconberg JL, Schmidt LC, Volk HE, Tassone F. PMID: 26073892; PMCID: PMC4871694.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Correction: Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss. PLoS Genet. 2015 Jun; 11(6):e1005293.
Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. PMID: 26068505; PMCID: PMC4465750.
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PubMed Mentions:
2 Fields:
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The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports. 2015 Jul 14; 5(1):125-38.
Zhou X, Crow AL, Hartiala J, Spindler TJ, Ghazalpour A, Barsky LW, Bennett BJ, Parks BW, Eskin E, Jain R, Epstein JA, Lusis AJ, Adams GB, Allayee H. PMID: 26050929; PMCID: PMC4618249.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. PLoS Genet. 2015 Apr; 11(4):e1005094.
Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA. PMID: 25880434; PMCID: PMC4399881.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension. Invest Ophthalmol Vis Sci. 2015 Apr; 56(4):2737-48.
Jeong S, Patel N, Edlund CK, Hartiala J, Hazelett DJ, Itakura T, Wu PC, Avery RL, Davis JL, Flynn HW, Lalwani G, Puliafito CA, Wafapoor H, Hijikata M, Keicho N, Gao X, Argüeso P, Allayee H, Coetzee GA, Pletcher MT, Conti DV, Schwartz SG, Eaton AM, Fini ME. PMID: 25813999; PMCID: PMC4416661.
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PubMed Mentions:
14 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansPHPublic Health
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View in:
PubMed Mentions:
4 Fields:
Translation:
HumansPHPublic Health
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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature. 2015 Feb 05; 518(7537):102-6.
Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, NHLBI Exome Sequencing Project, Girelli D, Martinelli N, Farlow DN, DePristo MA, Roberts R, Stewart AF, Saleheen D, Danesh J, Epstein SE, Sivapalaratnam S, Hovingh GK, Kastelein JJ, Samani NJ, Schunkert H, Erdmann J, Shah SH, Kraus WE, Davies R, Nikpay M, Johansen CT, Wang J, Hegele RA, Hechter E, Marz W, Kleber ME, Huang J, Johnson AD, Li M, Burke GL, Gross M, Liu Y, Assimes TL, Heiss G, Lange EM, Folsom AR, Taylor HA, Olivieri O, Hamsten A, Clarke R, Reilly DF, Yin W, Rivas MA, Donnelly P, Rossouw JE, Psaty BM, Herrington DM, Wilson JG, Rich SS, Bamshad MJ, Tracy RP, Cupples LA, Rader DJ, Reilly MP, Spertus JA, Cresci S, Hartiala J, Tang WH, Hazen SL, Allayee H, Reiner AP, Carlson CS, Kooperberg C, Jackson RD, Boerwinkle E, Lander ES, Schwartz SM, Siscovick DS, McPherson R, Tybjaerg-Hansen A, Abecasis GR, Watkins H, Nickerson DA, Ardissino D, Sunyaev SR, O'Donnell CJ, Altshuler D, Gabriel S, Kathiresan S. PMID: 25487149; PMCID: PMC4319990.
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PubMed Mentions:
295 Fields:
Translation:
Humans
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Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans. Diabetologia. 2014 Jul; 57(7):1391-9.
Ren J, Xiang AH, Trigo E, Takayanagi M, Beale E, Lawrence JM, Hartiala J, Richey JM, Allayee H, Buchanan TA, Watanabe RM. PMID: 24728128; PMCID: PMC4117246.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine. Arterioscler Thromb Vasc Biol. 2014 Jun; 34(6):1307-13.
Hartiala J, Bennett BJ, Tang WH, Wang Z, Stewart AF, Roberts R, McPherson R, Lusis AJ, Hazen SL, Allayee H, CARDIoGRAM Consortium. PMID: 24675659; PMCID: PMC4035110.
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PubMed Mentions:
65 Fields:
Translation:
HumansAnimalsCells
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Macrophages and fibrosis in adipose tissue are linked to liver damage and metabolic risk in obese children. Obesity (Silver Spring). 2014 Jun; 22(6):1512-9.
Walker RW, Allayee H, Inserra A, Fruhwirth R, Alisi A, Devito R, Carey ME, Sinatra F, Goran MI, Nobili V. PMID: 24616207; PMCID: PMC4037344.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Cognition, mood, and physiological concentrations of sex hormones in the early and late postmenopause. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20290-5.
Henderson VW, St John JA, Hodis HN, McCleary CA, Stanczyk FZ, Karim R, Shoupe D, Kono N, Dustin L, Allayee H, Mack WJ. PMID: 24277815; PMCID: PMC3864289.
View in:
PubMed Mentions:
37 Fields:
Translation:
Humans
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Habitual diets rich in dark-green vegetables are associated with an increased response to ω-3 fatty acid supplementation in Americans of African ancestry. J Nutr. 2014 Feb; 144(2):123-31.
O'Sullivan A, Armstrong P, Schuster GU, Pedersen TL, Allayee H, Stephensen CB, Newman JW. PMID: 24259553; PMCID: PMC3901419.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Modifying influence of dietary sugar in the relationship between cortisol and visceral adipose tissue in minority youth. Obesity (Silver Spring). 2014 Feb; 22(2):474-81.
Gyllenhammer LE, Weigensberg MJ, Spruijt-Metz D, Allayee H, Goran MI, Davis JN. PMID: 23929660; PMCID: PMC3946447.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Adipose tissue 11βHSD1 gene expression, βcell function and ectopic fat in obese African Americans versus Hispanics. Obesity (Silver Spring). 2014 Jan; 22(1):14-8.
Gyllenhammer LE, Alderete TL, Mahurka S, Allayee H, Goran MI. PMID: 23836520.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Genetic and clinical markers of elevated liver fat content in overweight and obese Hispanic children. Obesity (Silver Spring). 2013 Dec; 21(12):E790-7.
Walker RW, Sinatra F, Hartiala J, Weigensberg M, Spruijt-Metz D, Alderete TL, Goran MI, Allayee H. PMID: 23804528; PMCID: PMC3855210.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Two chromosome 9p21 haplotype blocks distinguish between coronary artery disease and myocardial infarction risk. Circ Cardiovasc Genet. 2013 Aug; 6(4):372-80.
Fan M, Dandona S, McPherson R, Allayee H, Hazen SL, Wells GA, Roberts R, Stewart AF. PMID: 23729007; PMCID: PMC3839299.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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ALOX5 polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma. Clin Exp Allergy. 2013 May; 43(5):512-20.
Mougey E, Lang JE, Allayee H, Teague WG, Dozor AJ, Wise RA, Lima JJ. PMID: 23600541; PMCID: PMC3633142.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Hum Mol Genet. 2013 Aug 15; 22(16):3381-93.
Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, Ojeda F, Müller-Nurasyid M, Munzel TF, Psaty BM, Rice K, Rotter JI, Schnabel RB, Tang WH, Thorand B, Erdmann J, CARDIoGRAM Consortium, Jacobs DR, Wilson JG, Koenig W, Tracy RP, Blankenberg S, März W, Gross MD, Benjamin EJ, Hazen SL, Allayee H. PMID: 23620142; PMCID: PMC3723315.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2). J Biol Chem. 2013 Apr 26; 288(17):11940-8.
Zhou G, Marathe GK, Hartiala J, Hazen SL, Allayee H, Tang WH, McIntyre TM. PMID: 23508960; PMCID: PMC3636881.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. J Am Coll Cardiol. 2013 Mar 05; 61(9):957-70.
Chan K, Patel RS, Newcombe P, Nelson CP, Qasim A, Epstein SE, Burnett S, Vaccarino VL, Zafari AM, Shah SH, Anderson JL, Carlquist JF, Hartiala J, Allayee H, Hinohara K, Lee BS, Erl A, Ellis KL, Goel A, Schaefer AS, El Mokhtari NE, Goldstein BA, Hlatky MA, Go AS, Shen GQ, Gong Y, Pepine C, Laxton RC, Whittaker JC, Tang WH, Johnson JA, Wang QK, Assimes TL, Nöthlings U, Farrall M, Watkins H, Richards AM, Cameron VA, Muendlein A, Drexel H, Koch W, Park JE, Kimura A, Shen WF, Simpson IA, Hazen SL, Horne BD, Hauser ER, Quyyumi AA, Reilly MP, Samani NJ, Ye S. PMID: 23352782; PMCID: PMC3653306.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metab. 2013 Jan 08; 17(1):49-60.
Bennett BJ, de Aguiar Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ. PMID: 23312283; PMCID: PMC3771112.
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PubMed Mentions:
437 Fields:
Translation:
HumansAnimalsCells
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Nutrigenetic response to omega-3 fatty acids in obese asthmatics (NOOA): rationale and methods. Contemp Clin Trials. 2013 Mar; 34(2):326-35.
Lang JE, Mougey EB, Allayee H, Blake KV, Lockey R, Gong Y, Hossain J, Killen K, Lima JJ, Nemours Network for Asthma Research. PMID: 23298524; PMCID: PMC3638234.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Seventy-five genetic loci influencing the human red blood cell. Nature. 2012 Dec 20; 492(7429):369-75.
van der Harst P, Zhang W, Mateo Leach I, Rendon A, Verweij N, Sehmi J, Paul DS, Elling U, Allayee H, Li X, Radhakrishnan A, Tan ST, Voss K, Weichenberger CX, Albers CA, Al-Hussani A, Asselbergs FW, Ciullo M, Danjou F, Dina C, Esko T, Evans DM, Franke L, Gögele M, Hartiala J, Hersch M, Holm H, Hottenga JJ, Kanoni S, Kleber ME, Lagou V, Langenberg C, Lopez LM, Lyytikäinen LP, Melander O, Murgia F, Nolte IM, O'Reilly PF, Padmanabhan S, Parsa A, Pirastu N, Porcu E, Portas L, Prokopenko I, Ried JS, Shin SY, Tang CS, Teumer A, Traglia M, Ulivi S, Westra HJ, Yang J, Zhao JH, Anni F, Abdellaoui A, Attwood A, Balkau B, Bandinelli S, Bastardot F, Benyamin B, Boehm BO, Cookson WO, Das D, de Bakker PI, de Boer RA, de Geus EJ, de Moor MH, Dimitriou M, Domingues FS, Döring A, Engström G, Eyjolfsson GI, Ferrucci L, Fischer K, Galanello R, Garner SF, Genser B, Gibson QD, Girotto G, Gudbjartsson DF, Harris SE, Hartikainen AL, Hastie CE, Hedblad B, Illig T, Jolley J, Kähönen M, Kema IP, Kemp JP, Liang L, Lloyd-Jones H, Loos RJ, Meacham S, Medland SE, Meisinger C, Memari Y, Mihailov E, Miller K, Moffatt MF, Nauck M, Novatchkova M, Nutile T, Olafsson I, Onundarson PT, Parracciani D, Penninx BW, Perseu L, Piga A, Pistis G, Pouta A, Puc U, Raitakari O, Ring SM, Robino A, Ruggiero D, Ruokonen A, Saint-Pierre A, Sala C, Salumets A, Sambrook J, Schepers H, Schmidt CO, Silljé HH, Sladek R, Smit JH, Starr JM, Stephens J, Sulem P, Tanaka T, Thorsteinsdottir U, Tragante V, van Gilst WH, van Pelt LJ, van Veldhuisen DJ, Völker U, Whitfield JB, Willemsen G, Winkelmann BR, Wirnsberger G, Algra A, Cucca F, d'Adamo AP, Danesh J, Deary IJ, Dominiczak AF, Elliott P, Fortina P, Froguel P, Gasparini P, Greinacher A, Hazen SL, Jarvelin MR, Khaw KT, Lehtimäki T, Maerz W, Martin NG, Metspalu A, Mitchell BD, Montgomery GW, Moore C, Navis G, Pirastu M, Pramstaller PP, Ramirez-Solis R, Schadt E, Scott J, Shuldiner AR, Smith GD, Smith JG, Snieder H, Sorice R, Spector TD, Stefansson K, Stumvoll M, Tang WH, Toniolo D, Tönjes A, Visscher PM, Vollenweider P, Wareham NJ, Wolffenbuttel BH, Boomsma DI, Beckmann JS, Dedoussis GV, Deloukas P, Ferreira MA, Sanna S, Uda M, Hicks AA, Penninger JM, Gieger C, Kooner JS, Ouwehand WH, Soranzo N, Chambers JC. PMID: 23222517; PMCID: PMC3623669.
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PubMed Mentions:
202 Fields:
Translation:
HumansAnimalsCells
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Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2803-12.
Tang WH, Hartiala J, Fan Y, Wu Y, Stewart AF, Erdmann J, Kathiresan S, CARDIoGRAM Consortium, Roberts R, McPherson R, Allayee H, Hazen SL. PMID: 22982463; PMCID: PMC3499946.
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PubMed Mentions:
68 Fields:
Translation:
HumansCells
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Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012 Oct; 23(9-10):680-92.
Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC. PMID: 22892838; PMCID: PMC3586763.
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PubMed Mentions:
90 Fields:
Translation:
Animals
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CXCL5 polymorphisms are associated with variable blood pressure in cardiovascular disease-free adults. Hum Genomics. 2012 Aug 02; 6:9.
Beitelshees AL, Aquilante CL, Allayee H, Langaee TY, Welder GJ, Schofield RS, Zineh I. PMID: 23245743; PMCID: PMC3505480.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography. Circ Cardiovasc Genet. 2012 Aug 01; 5(4):441-9.
Patel RS, Sun YV, Hartiala J, Veledar E, Su S, Sher S, Liu YX, Rahman A, Patel R, Rab ST, Vaccarino V, Zafari AM, Samady H, Tang WH, Allayee H, Hazen SL, Quyyumi AA. PMID: 22767652; PMCID: PMC3459582.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Genetic-related and carbohydrate-related factors affecting liver fat accumulation. Curr Opin Clin Nutr Metab Care. 2012 Jul; 15(4):392-6.
Goran MI, Walker R, Allayee H. PMID: 22617559; PMCID: PMC3559241.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans. J Nutr. 2012 Aug; 142(8):1417-28.
Armstrong P, Kelley DS, Newman JW, Staggers FE, Hartiala J, Allayee H, Stephensen CB. PMID: 22739369; PMCID: PMC3397335.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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View in:
PubMed Mentions:
152 Fields:
Translation:
Humans
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Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. Obesity (Silver Spring). 2012 Oct; 20(10):2083-92.
Farook VS, Puppala S, Schneider J, Fowler SP, Chittoor G, Dyer TD, Allayee H, Cole SA, Arya R, Black MH, Curran JE, Almasy L, Buchanan TA, Jenkinson CP, Lehman DM, Watanabe RM, Blangero J, Duggirala R. PMID: 22456541; PMCID: PMC4287372.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Association of PLA2G4A with myocardial infarction is modulated by dietary PUFAs. Am J Clin Nutr. 2012 Apr; 95(4):959-65.
Hartiala J, Gilliam E, Vikman S, Campos H, Allayee H. PMID: 22378731; PMCID: PMC3302367.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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New gene functions in megakaryopoiesis and platelet formation. Nature. 2011 Nov 30; 480(7376):201-8.
Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Mägi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, Gögele M, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, Döring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Khaw KT, Kühnel B, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW, Nakamura Y, Nauck M, Navis G, Nöthlings U, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, Tönjes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, Völker U, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N. PMID: 22139419; PMCID: PMC3335296.
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PubMed Mentions:
214 Fields:
Translation:
HumansAnimalsCells
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Clinical and genetic association of serum ceruloplasmin with cardiovascular risk. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):516-22.
Tang WH, Wu Y, Hartiala J, Fan Y, Stewart AF, Roberts R, McPherson R, Fox PL, Allayee H, Hazen SL. PMID: 22075249; PMCID: PMC3262121.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway. Diabetes. 2011 Nov; 60(11):2802-9.
Lê KA, Mahurkar S, Alderete TL, Hasson RE, Adam TC, Kim JS, Beale E, Xie C, Greenberg AS, Allayee H, Goran MI. PMID: 22025778; PMCID: PMC3198061.
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PubMed Mentions:
69 Fields:
Translation:
HumansCellsCTClinical Trials
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Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome. BMC Med Genet. 2011 Sep 29; 12:127.
Morgan TM, House JA, Cresci S, Jones P, Allayee H, Hazen SL, Patel Y, Patel RS, Eapen DJ, Waddy SP, Quyyumi AA, Kleber ME, März W, Winkelmann BR, Boehm BO, Krumholz HM, Spertus JA. PMID: 21957892; PMCID: PMC3190329.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
123 Fields:
Translation:
Humans
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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 2011 Apr 07; 472(7341):57-63.
Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, Feldstein AE, Britt EB, Fu X, Chung YM, Wu Y, Schauer P, Smith JD, Allayee H, Tang WH, DiDonato JA, Lusis AJ, Hazen SL. PMID: 21475195; PMCID: PMC3086762.
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PubMed Mentions:
2219 Fields:
Translation:
HumansAnimalsCells
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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar 06; 43(4):333-8.
Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I, Cardiogenics, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J, CARDIoGRAM Consortium, Samani NJ. PMID: 21378990; PMCID: PMC3119261.
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PubMed Mentions:
921 Fields:
Translation:
Humans
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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet. 2011 Feb 10; 7(2):e1001300.
Lettre G, Palmer CD, Young T, Ejebe KG, Allayee H, Benjamin EJ, Bennett F, Bowden DW, Chakravarti A, Dreisbach A, Farlow DN, Folsom AR, Fornage M, Forrester T, Fox E, Haiman CA, Hartiala J, Harris TB, Hazen SL, Heckbert SR, Henderson BE, Hirschhorn JN, Keating BJ, Kritchevsky SB, Larkin E, Li M, Rudock ME, McKenzie CA, Meigs JB, Meng YA, Mosley TH, Newman AB, Newton-Cheh CH, Paltoo DN, Papanicolaou GJ, Patterson N, Post WS, Psaty BM, Qasim AN, Qu L, Rader DJ, Redline S, Reilly MP, Reiner AP, Rich SS, Rotter JI, Liu Y, Shrader P, Siscovick DS, Tang WH, Taylor HA, Tracy RP, Vasan RS, Waters KM, Wilks R, Wilson JG, Fabsitz RR, Gabriel SB, Kathiresan S, Boerwinkle E. PMID: 21347282; PMCID: PMC3037413.
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PubMed Mentions:
197 Fields:
Translation:
Humans
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Genetic contribution of the leukotriene pathway to coronary artery disease. Hum Genet. 2011 Jun; 129(6):617-27.
Hartiala J, Li D, Conti DV, Vikman S, Patel Y, Tang WH, Brennan ML, Newman JW, Stephensen CB, Armstrong P, Hazen SL, Allayee H. PMID: 21293878; PMCID: PMC3092945.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation. J Lipid Res. 2011 May; 52(5):991-1003.
Stephensen CB, Armstrong P, Newman JW, Pedersen TL, Legault J, Schuster GU, Kelley D, Vikman S, Hartiala J, Nassir R, Seldin MF, Allayee H. PMID: 21296957; PMCID: PMC3073473.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Genetic risk score and risk of myocardial infarction in Hispanics. Circulation. 2011 Feb 01; 123(4):374-80.
Qi L, Ma J, Qi Q, Hartiala J, Allayee H, Campos H. PMID: 21242481; PMCID: PMC3076095.
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PubMed Mentions:
57 Fields:
Translation:
Humans
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Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet. 2011 Jan 29; 377(9763):383-92.
Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS, Myocardial Infarction Genetics Consortium, Wellcome Trust Case Control Consortium, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ. PMID: 21239051; PMCID: PMC3297116.
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PubMed Mentions:
224 Fields:
Translation:
Humans
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Inflammatory gene variants in the Tsimane, an indigenous Bolivian population with a high infectious load. Biodemography Soc Biol. 2011; 57(1):33-52.
Vasunilashorn S, Finch CE, Crimmins EM, Vikman SA, Stieglitz J, Gurven M, Kaplan H, Allayee H. PMID: 21845926; PMCID: PMC3529658.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption. Am J Clin Nutr. 2010 Dec; 92(6):1522-7.
Davis JN, Lê KA, Walker RW, Vikman S, Spruijt-Metz D, Weigensberg MJ, Allayee H, Goran MI. PMID: 20962157; PMCID: PMC2980971.
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PubMed Mentions:
88 Fields:
Translation:
Humans
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Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents. Diabetes. 2010 Dec; 59(12):3127-30.
Goran MI, Walker R, Le KA, Mahurkar S, Vikman S, Davis JN, Spruijt-Metz D, Weigensberg MJ, Allayee H. PMID: 20852027; PMCID: PMC2992774.
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PubMed Mentions:
55 Fields:
Translation:
Humans
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A novel g.-1258G>A mutation in a conserved putative regulatory element of PAX9 is associated with autosomal dominant molar hypodontia. Clin Genet. 2011 Sep; 80(3):265-72.
Mendoza-Fandino GA, Gee JM, Ben-Dor S, Gonzalez-Quevedo C, Lee K, Kobayashi Y, Hartiala J, Myers RM, Leal SM, Allayee H, Patel PI. PMID: 21443745; PMCID: PMC6240906.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy. J Lipid Res. 2010 Oct; 51(10):3055-61.
Nicholls SJ, Tang WH, Scoffone H, Brennan DM, Hartiala J, Allayee H, Hazen SL. PMID: 20601648; PMCID: PMC2936758.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics. J Nutrigenet Nutrigenomics. 2009; 2(3):140-8.
Allayee H, Roth N, Hodis HN. PMID: 19776641; PMCID: PMC2820567.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose. Diabetes. 2009 Dec; 58(12):2946-53.
Li X, Shu YH, Xiang AH, Trigo E, Kuusisto J, Hartiala J, Swift AJ, Kawakubo M, Stringham HM, Bonnycastle LL, Lawrence JM, Laakso M, Allayee H, Buchanan TA, Watanabe RM. PMID: 19741163; PMCID: PMC2780888.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Functional analysis of 5-lipoxygenase promoter repeat variants. Hum Mol Genet. 2009 Dec 01; 18(23):4521-9.
Vikman S, Brena RM, Armstrong P, Hartiala J, Stephensen CB, Allayee H. PMID: 19717473; PMCID: PMC2773268.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCellsCTClinical Trials
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Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans. J Clin Endocrinol Metab. 2009 Oct; 94(10):4094-102.
Shu YH, Hartiala J, Xiang AH, Trigo E, Lawrence JM, Allayee H, Buchanan TA, Bottini N, Watanabe RM. PMID: 19622628; PMCID: PMC2758733.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Genotyping the GGGCGG tandem repeat promoter polymorphism in the 5-lipoxygenase enzyme gene (ALOX5) by pyrosequencing assay. Genet Test Mol Biomarkers. 2009 Jun; 13(3):361-5.
Schentrup AM, Allayee H, Lima JJ, Johnson JA, Langaee TY. PMID: 19473080; PMCID: PMC2998028.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans. Obesity (Silver Spring). 2009 Apr; 17(4):729-36.
Li X, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA, Watanabe RM. PMID: 19148120; PMCID: PMC4357482.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus. Hum Mol Genet. 2009 Feb 01; 18(3):569-79.
Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S, Italian Collaborative Group, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, Pons-Estel B, Alarcon-Riquelme ME, He Y, Zhang ZY, Allayee H, Chen XS, Martin J, Bottini N. PMID: 18981062; PMCID: PMC2722189.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. Am J Clin Nutr. 2008 Oct; 88(4):934-40.
Allayee H, Baylin A, Hartiala J, Wijesuriya H, Mehrabian M, Lusis AJ, Campos H. PMID: 18842779; PMCID: PMC3014055.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Identification of ALOX5 as a gene regulating adiposity and pancreatic function. Diabetologia. 2008 Jun; 51(6):978-88.
Mehrabian M, Schulthess FT, Nebohacova M, Castellani LW, Zhou Z, Hartiala J, Oberholzer J, Lusis AJ, Maedler K, Allayee H. PMID: 18421434; PMCID: PMC2835627.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimals
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Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease. Hum Genet. 2008 May; 123(4):399-408.
Assimes TL, Knowles JW, Priest JR, Basu A, Volcik KA, Southwick A, Tabor HK, Hartiala J, Allayee H, Grove ML, Tabibiazar R, Sidney S, Fortmann SP, Go A, Hlatky M, Iribarren C, Boerwinkle E, Myers R, Risch N, Quertermous T. PMID: 18369664; PMCID: PMC4023692.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA. 2008 Mar 19; 299(11):1265-76.
Bhattacharyya T, Nicholls SJ, Topol EJ, Zhang R, Yang X, Schmitt D, Fu X, Shao M, Brennan DM, Ellis SG, Brennan ML, Allayee H, Lusis AJ, Hazen SL. PMID: 18349088; PMCID: PMC3014051.
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PubMed Mentions:
222 Fields:
Translation:
Humans
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Allgrove syndrome in a Mexican American family is caused by an ancestral mutation derived from North Africa. Clin Genet. 2008 Apr; 73(4):385-7.
Chang AJ, Kline MM, Currie Y, Perez MO, Hartiala J, Wijesuriya H, Buchanan TA, Watanabe RM, Allayee H. PMID: 18261130.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Prevalence of common disease-associated variants in Asian Indians. BMC Genet. 2008 Feb 04; 9:13.
Pemberton TJ, Mehta NU, Witonsky D, Di Rienzo A, Allayee H, Conti DV, Patel PI. PMID: 18248681; PMCID: PMC2267478.
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PubMed Mentions:
21 Fields:
Translation:
Humans
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Non-conventional genetic risk factors for cardiovascular disease. World Rev Nutr Diet. 2008; 98:62-76.
Allayee H. PMID: 18806462.
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PubMed Mentions: Fields:
Translation:
Humans
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Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes. 2008 Apr; 57(4):1048-56.
Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM. PMID: 18162503; PMCID: PMC4447520.
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PubMed Mentions:
29 Fields:
Translation:
HumansCells
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FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice. Toxicol Sci. 2007 Dec; 100(2):474-85.
Martin LJ, Chen H, Liao X, Allayee H, Shih DM, Lee GS, Hovland DN, Robbins WA, Carnes K, Hess RA, Lusis AJ, Collins MD. PMID: 17785681.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics. Chest. 2007 Sep; 132(3):868-74.
Allayee H, Hartiala J, Lee W, Mehrabian M, Irvin CG, Conti DV, Lima JJ. PMID: 17646220.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care. 2007 Jul; 30 Suppl 2:S134-40.
Watanabe RM, Black MH, Xiang AH, Allayee H, Lawrence JM, Buchanan TA. PMID: 17596461; PMCID: PMC2925642.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans. Diabetes. 2007 May; 56(5):1481-5.
Watanabe RM, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA. PMID: 17317761; PMCID: PMC2925638.
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PubMed Mentions:
61 Fields:
Translation:
Humans
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A new locus for autosomal dominant amelogenesis imperfecta on chromosome 8q24.3. Hum Genet. 2007 Jan; 120(5):653-62.
Mendoza G, Pemberton TJ, Lee K, Scarel-Caminaga R, Mehrian-Shai R, Gonzalez-Quevedo C, Ninis V, Hartiala J, Allayee H, Snead ML, Leal SM, Line SR, Patel PI. PMID: 17024372; PMCID: PMC6174526.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Effect of obesity on clinical presentation and response to treatment in asthma. J Asthma. 2006 Sep; 43(7):553-8.
Dixon AE, Shade DM, Cohen RI, Skloot GS, Holbrook JT, Smith LJ, Lima JJ, Allayee H, Irvin CG, Wise RA, American Lung Association-Asthma Clinical Research Centers. PMID: 16939998.
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PubMed Mentions:
47 Fields:
Translation:
Humans
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Nonconventional genetic risk factors for cardiovascular disease. Curr Atheroscler Rep. 2006 May; 8(3):184-92.
Tymchuk CN, Hartiala J, Patel PI, Mehrabian M, Allayee H. PMID: 16640955.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimals
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Using inbred mouse strains to identify genes for complex diseases. Front Biosci. 2006 May 01; 11:1216-26.
Allayee H, Andalibi A, Mehrabian M. PMID: 16368507.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am J Respir Crit Care Med. 2006 Feb 15; 173(4):379-85.
Lima JJ, Zhang S, Grant A, Shao L, Tantisira KG, Allayee H, Wang J, Sylvester J, Holbrook J, Wise R, Weiss ST, Barnes K. PMID: 16293801; PMCID: PMC2662939.
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PubMed Mentions:
83 Fields:
Translation:
Humans
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Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits. Nat Genet. 2005 Nov; 37(11):1224-33.
Mehrabian M, Allayee H, Stockton J, Lum PY, Drake TA, Castellani LW, Suh M, Armour C, Edwards S, Lamb J, Lusis AJ, Schadt EE. PMID: 16200066.
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PubMed Mentions:
106 Fields:
Translation:
Animals
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A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. Genomics. 2005 Sep; 86(3):259-70.
Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ. PMID: 16039824.
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PubMed Mentions:
17 Fields:
Translation:
Animals
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The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet. 2004 Nov; 36(11):1133-7.
Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F, Complex Trait Consortium. PMID: 15514660.
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PubMed Mentions:
590 Fields:
Translation:
HumansAnimals
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Vascular cross-talk: a conversation. Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1748-9.
Mehrabian M, Allayee H. PMID: 15472137.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees. Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1935-41.
Cantor RM, de Bruin T, Kono N, Napier S, van Nas A, Allayee H, Lusis AJ. PMID: 15308552.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ Res. 2004 Apr 16; 94(7):993-9.
Mar R, Pajukanta P, Allayee H, Groenendijk M, Dallinga-Thie G, Krauss RM, Sinsheimer JS, Cantor RM, de Bruin TW, Lusis AJ. PMID: 15001527.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. N Engl J Med. 2004 Jan 01; 350(1):29-37.
Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, Mar R, Lusis AJ, Mehrabian M. PMID: 14702425.
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PubMed Mentions:
157 Fields:
Translation:
Humans
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5-lipoxygenase and atherosclerosis. Curr Opin Lipidol. 2003 Oct; 14(5):447-57.
Mehrabian M, Allayee H. PMID: 14501583.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Using mice to dissect genetic factors in atherosclerosis. Arterioscler Thromb Vasc Biol. 2003 Sep 01; 23(9):1501-9.
Allayee H, Ghazalpour A, Lusis AJ. PMID: 12920046.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia. Circ Res. 2003 Jun 13; 92(11):1262-7.
Allayee H, Castellani LW, Cantor RM, de Bruin TW, Lusis AJ. PMID: 12738753.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. Am J Hum Genet. 2003 Apr; 72(4):903-17.
Pajukanta P, Allayee H, Krass KL, Kuraishy A, Soro A, Lilja HE, Mar R, Taskinen MR, Nuotio I, Laakso M, Rotter JI, de Bruin TW, Cantor RM, Lusis AJ, Peltonen L. PMID: 12638083; PMCID: PMC1180353.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. Circ Res. 2002 Jul 26; 91(2):120-6.
Mehrabian M, Allayee H, Wong J, Shi W, Wang XP, Shaposhnik Z, Funk CD, Lusis AJ, Shih W. PMID: 12142344.
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PubMed Mentions:
101 Fields:
Translation:
AnimalsCells
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Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circ Res. 2002 May 03; 90(8):926-31.
Allayee H, Krass KL, Pajukanta P, Cantor RM, van der Kallen CJ, Mar R, Rotter JI, de Bruin TW, Peltonen L, Lusis AJ. PMID: 11988495.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Understanding atherosclerosis through mouse genetics. Curr Opin Lipidol. 2002 Apr; 13(2):181-9.
Sheth SS, Deluna A, Allayee H, Lusis AJ. PMID: 11891421.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p. Hypertension. 2001 Oct; 38(4):773-8.
Allayee H, de Bruin TW, Michelle Dominguez K, Cheng LS, Ipp E, Cantor RM, Krass KL, Keulen ET, Aouizerat BE, Lusis AJ, Rotter JI. PMID: 11641285.
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PubMed Mentions:
40 Fields:
Translation:
HumansCells
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Biochemistry. An absorbing study of cholesterol. Science. 2000 Dec 01; 290(5497):1709-11.
Allayee H, Laffitte BA, Lusis AJ. PMID: 11186392.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A. Int J Obes Relat Metab Disord. 2000 Nov; 24(11):1381-91.
van der Kallen CJ, Cantor RM, van Greevenbroek MM, Geurts JM, Bouwman FG, Aouizerat BE, Allayee H, Buurman WA, Lusis AJ, Rotter JI, de Bruin TW. PMID: 11126332.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Identification of TNFRSF1B as a novel modifier gene in familial combined hyperlipidemia. Hum Mol Genet. 2000 Sep 01; 9(14):2067-74.
Geurts JM, Janssen RG, van Greevenbroek MM, van der Kallen CJ, Cantor RM, Bu X, Aouizerat BE, Allayee H, Rotter JI, de Bruin TW. PMID: 10958645.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2. J Lipid Res. 2000 Apr; 41(4):573-82.
Mouzeyan A, Choi J, Allayee H, Wang X, Sinsheimer J, Phan J, Castellani LW, Reue K, Lusis AJ, Davis RC. PMID: 10744778.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. J Lipid Res. 2000 Feb; 41(2):245-52.
Allayee H, Dominguez KM, Aouizerat BE, Krauss RM, Rotter JI, Lu J, Cantor RM, de Bruin TW, Lusis AJ. PMID: 10681408.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Linkage of a candidate gene locus to familial combined hyperlipidemia: lecithin:cholesterol acyltransferase on 16q. Arterioscler Thromb Vasc Biol. 1999 Nov; 19(11):2730-6.
Aouizerat BE, Allayee H, Cantor RM, Dallinga-Thie GM, Lanning CD, de Bruin TW, Lusis AJ, Rotter JI. PMID: 10559018.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11. Am J Hum Genet. 1999 Aug; 65(2):397-412.
Aouizerat BE, Allayee H, Cantor RM, Davis RC, Lanning CD, Wen PZ, Dallinga-Thie GM, de Bruin TW, Rotter JI, Lusis AJ. PMID: 10417282; PMCID: PMC1377938.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Novel genes for familial combined hyperlipidemia. Curr Opin Lipidol. 1999 Apr; 10(2):113-22.
Aouizerat BE, Allayee H, Bodnar J, Krass KL, Peltonen L, de Bruin TW, Rotter JI, Lusis AJ. PMID: 10327279.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
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Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype. Am J Hum Genet. 1998 Aug; 63(2):577-85.
Allayee H, Aouizerat BE, Cantor RM, Dallinga-Thie GM, Krauss RM, Lanning CD, Rotter JI, Lusis AJ, de Bruin TW. PMID: 9683614; PMCID: PMC1377323.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J Clin Invest. 1994 Aug; 94(2):877-84.
Liao F, Andalibi A, Qiao JH, Allayee H, Fogelman AM, Lusis AJ. PMID: 8040344; PMCID: PMC296170.
View in:
PubMed Mentions:
30 Fields:
Translation:
AnimalsCells