Hooman Allayee, PhD

Title(s)Professor of Population and Public Health Sciences
SchoolKeck School of Medicine of Usc
AddressCSC CSC202
Health Sciences Campus
Los Angeles CA 90089-9075
Phone+1 323 442 1736
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    Collapse Biography 
    Collapse Education and Training
    UCLA, Los Angeles, CABS06/1994Biology
    UCLA, Los Angelesl, CAMA12/1998Genetics
    UCLA, Los Angeles, CAPhD12/1999Genetics

    Collapse Overview 
    Collapse Overview
    Dr. Allayee is Professor of Populations & Public Health Sciences and Biochemistry & Molecular Medicine at the Keck School of Medicine of USC. His research program is focused on using multi-disciplinary genetics/genomics approaches to understand complex disorders, with an emphasis on cardiovascular, metabolic, and inflammatory diseases. In particular, his laboratory employs systems genetics strategies to dissect the architecture of complex diseases where a variety of intermediate phenotypes at the molecular, proteomic, and metabolomic levels are integrated into the genetic analyses. Current projects involve large-scale population studies in humans, gene-environment interactions, functional experiments using molecular genetics techniques, and the generation and characterization of mouse models. Prior to joining USC, Dr. Allayee completed NIH Postdoctoral Fellowships at Harbor-UCLA Medical Center and the David Geffen School of Medicine UCLA.

    Collapse Research 
    Collapse Research Activities and Funding
    Biological Mechanisms through which TMAO Promotes Atherosclerosis
    NIH R01HL148110Apr 20, 2020 - Feb 29, 2024
    Role: Principal Investigator
    Role of Glycine Metabolism in Cardiovascular Disease
    NIH R01HL133169Feb 1, 2017 - Jan 31, 2021
    Role: Principal Investigator
    Nutrigenetic Intervention to Reduce Liver Fat in Hispanics - Supplement
    NIH R01MD010358Mar 24, 2016 - Nov 30, 2020
    Role: Co-Principal Investigator
    Genetic and Environmental Determinants of Asthma Endophenotypes
    NIH R01ES025786Aug 1, 2015 - Apr 30, 2021
    Role: Co-Principal Investigator
    INTEGRATIVE GENETIC APPROACHES TO GENE-AIR POLLUTION INTERACTIONS IN ASTHMA
    NIH R01ES021801Aug 1, 2012 - Oct 31, 2019
    Role: Co-Principal Investigator
    Role of the 5-Lipoxygenase Pathway in Atherosclerosis
    NIH R01HL079353Aug 15, 2005 - Jun 30, 2011
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dihydroxyacetone phosphate is a novel predictor of hepatic fibrosis in Latino adolescents with obesity. J Pediatr Gastroenterol Nutr. 2024 Nov 25. Schenker RB, Ramirez CB, Jang C, Allayee H, Zhao X, Setchell KDR, Kohli R, Goran MI. PMID: 39582475.
      View in: PubMed   Mentions:    Fields:    
    2. Ambient air pollution exposure is associated with liver fat and stiffness in Latino youth with a more pronounced effect in those with PNPLA3 genotype and more advanced liver disease. Ecotoxicol Environ Saf. 2024 Oct 24; 286:117234. Schenker RB, Machle CJ, Allayee H, Lurmann F, Patterson WB, Kohli R, Goran MI, Alderete TL. PMID: 39454357.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    3. COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type. Arterioscler Thromb Vasc Biol. 2024 Oct 09. Hilser JR, Spencer NJ, Afshari K, Gilliland FD, Hu H, Deb A, Lusis AJ, Wilson Tang WH, Hartiala JA, Hazen SL, Allayee H. PMID: 39381876.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Reply to Guyton, J. R. & Boden, W. E.; Schreiber, S. et al. Nat Med. 2024 Sep; 30(9):2448-2449. Tang WHW, DiDonato JA, Allayee H, Hazen SL. PMID: 39237627.
      View in: PubMed   Mentions:    Fields:    
    5. Serum proteomic profiling of physical activity reveals CD300LG as a novel exerkine with a potential causal link to glucose homeostasis. Elife. 2024 Aug 27; 13. Lee-Ødegård S, Hjorth M, Olsen T, Moen GH, Daubney E, Evans DM, Hevener AL, Lusis AJ, Zhou M, Seldin MM, Allayee H, Hilser J, Viken JK, Gulseth H, Norheim F, Drevon CA, Birkeland KI. PMID: 39190027; PMCID: PMC11349297.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    6. Comprehensive Clinical and Genetic Analyses of Circulating Bile Acids and Their Associations With Diabetes and Its Indices. Diabetes. 2024 Aug 01; 73(8):1215-1228. Choucair I, Mallela DP, Hilser JR, Hartiala JA, Nemet I, Gogonea V, Li L, Lusis AJ, Fischbach MA, Tang WHW, Allayee H, Hazen SL. PMID: 38701355; PMCID: PMC11262044.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Publisher Correction: A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Nat Med. 2024 Jun; 30(6):1791. Ferrell M, Wang Z, Anderson JT, Li XS, Witkowski M, DiDonato JA, Hilser JR, Hartiala JA, Haghikia A, Cajka T, Fiehn O, Sangwan N, Demuth I, König M, Steinhagen-Thiessen E, Landmesser U, Tang WHW, Allayee H, Hazen SL. PMID: 38448791.
      View in: PubMed   Mentions: 1     Fields:    
    8. Associations of dietary sugars with liver stiffness in Latino adolescents with obesity differ on PNPLA3 and liver disease severity. Liver Int. 2024 Aug; 44(8):1768-1774. Schenker RB, Machle CJ, Schmidt KA, Allayee H, Kohli R, Goran MI. PMID: 38634702; PMCID: PMC11251846.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Effect of Hormone Therapy on Lipoprotein Subfractions in Early and Late Postmenopausal Women. J Clin Endocrinol Metab. 2024 Mar 28. Sriprasert I, Kim SS, Mohammed IE, Kono N, Karim R, Allayee H, Hodis HN, Mack WJ, Krauss RM. PMID: 38547457.
      View in: PubMed   Mentions:    Fields:    
    10. Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort. Metabolites. 2024 03 20; 14(3). Mirzaei S, DeVon HA, Cantor RM, Cupido AJ, Pan C, Ha SM, Fernandes Silva L, Hilser JR, Hartiala J, Allayee H, Rey FE, Laakso M, Lusis AJ. PMID: 38535334; PMCID: PMC10972019.
      View in: PubMed   Mentions: 2  
    11. A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk. Nat Med. 2024 Feb; 30(2):424-434. Ferrell M, Wang Z, Anderson JT, Li XS, Witkowski M, DiDonato JA, Hilser JR, Hartiala JA, Haghikia A, Cajka T, Fiehn O, Sangwan N, Demuth I, König M, Steinhagen-Thiessen E, Landmesser U, Tang WHW, Allayee H, Hazen SL. PMID: 38374343.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    12. Genetics unravels protein-metabolite relationships. Trends Endocrinol Metab. 2024 03; 35(3):183-184. Hilser JR, Lusis AJ, Allayee H. PMID: 38302401; PMCID: PMC10939837.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction. Circ Res. 2024 02 16; 134(4):371-389. Wang YC, Koay YC, Pan C, Zhou Z, Tang W, Wilcox J, Li XS, Zagouras A, Marques F, Allayee H, Rey FE, Kaye DM, O'Sullivan JF, Hazen SL, Cao Y, Lusis AJ. PMID: 38264909; PMCID: PMC10923103.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    14. Blocking CD226 regulates type 2 innate lymphoid cell effector function and alleviates airway hyperreactivity. J Allergy Clin Immunol. 2024 May; 153(5):1406-1422.e6. Sakano Y, Sakano K, Hurrell BP, Helou DG, Shafiei-Jahani P, Kazemi MH, Li X, Shen S, Hilser JR, Hartiala JA, Allayee H, Barbers R, Akbari O. PMID: 38244725.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    15. Effect of Genetic and Dietary Perturbation of Glycine Metabolism on Atherosclerosis in Humans and Mice. medRxiv. 2023 Dec 11. Biswas S, Hilser JR, Woodward NC, Wang Z, Gukasyan J, Nemet I, Schwartzman WS, Huang P, Han Y, Fouladian Z, Charugundla S, Spencer NJ, Pan C, Tang WHW, Lusis AJ, Hazen SL, Hartiala JA, Allayee H. PMID: 38168321; PMCID: PMC10760269.
      View in: PubMed   Mentions:
    16. Systems genetics approaches for understanding complex traits with relevance for human disease. Elife. 2023 11 14; 12. Allayee H, Farber CR, Seldin MM, Williams EG, James DE, Lusis AJ. PMID: 37962168; PMCID: PMC10645424.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Effects of Dietary Sugar Reduction on Biomarkers of Cardiometabolic Health in Latino Youth: Secondary Analyses from a Randomized Controlled Trial. Nutrients. 2023 Jul 27; 15(15). Schmidt KA, Mokhtari P, Holzhausen EA, Alderete TL, Allayee H, Nayak KS, Sinatra FR, Pickering TA, Mack W, Kohli R, Goran MI. PMID: 37571275; PMCID: PMC10420969.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Trimethylamine N-Oxide Response to a Mixed Macronutrient Tolerance Test in a Cohort of Healthy United States Adults. Int J Mol Sci. 2023 Jan 20; 24(3). James KL, Gertz ER, Kirschke CP, Allayee H, Huang L, Kable ME, Newman JW, Stephensen CB, Bennett BJ. PMID: 36768394; PMCID: PMC9917175.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure. Science. 2022 09 23; 377(6613):1399-1406. Cao Y, Wang Y, Zhou Z, Pan C, Jiang L, Zhou Z, Meng Y, Charugundla S, Li T, Allayee H, Seldin MM, Lusis AJ. PMID: 36137043; PMCID: PMC9639660.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    20. Role of gut microbe-derived metabolites in cardiometabolic diseases: Systems based approach. Mol Metab. 2022 10; 64:101557. Cao Y, Aquino-Martinez R, Hutchison E, Allayee H, Lusis AJ, Rey FE. PMID: 35870705; PMCID: PMC9399267.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    21. Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women. Clin Epigenetics. 2022 07 18; 14(1):90. Hilser JR, Hartiala JA, Sriprasert I, Kono N, Cai Z, Karim R, DeYoung J, Mack WJ, Hodis HN, Allayee H. PMID: 35850911; PMCID: PMC9295504.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Clinical Intervention to Reduce Dietary Sugar Does Not Affect Liver Fat in Latino Youth, Regardless of PNPLA3 Genotype: A Randomized Controlled Trial. J Nutr. 2022 07 06; 152(7):1655-1665. Schmidt KA, Jones RB, Rios C, Corona Y, Berger PK, Plows JF, Alderete TL, Fogel J, Hampson H, Hartiala JA, Cai Z, Allayee H, Nayak KS, Sinatra FR, Harlan G, Pickering TA, Salvy SJ, Mack WJ, Kohli R, Goran MI. PMID: 35218194; PMCID: PMC9258557.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Associations of Polymorphisms in the Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha Gene With Subsequent Coronary Heart Disease: An Individual-Level Meta-Analysis. Front Physiol. 2022; 13:909870. Schillemans T, Tragante V, Maitusong B, Gigante B, Cresci S, Laguzzi F, Vikström M, Richards M, Pilbrow A, Cameron V, Foco L, Doughty RN, Kuukasjärvi P, Allayee H, Hartiala JA, Tang WHW, Lyytikäinen LP, Nikus K, Laurikka JO, Srinivasan S, Mordi IR, Trompet S, Kraaijeveld A, van Setten J, Gijsberts CM, Maitland-van der Zee AH, Saely CH, Gong Y, Johnson JA, Cooper-DeHoff RM, Pepine CJ, Casu G, Leiherer A, Drexel H, Horne BD, van der Laan SW, Marziliano N, Hazen SL, Sinisalo J, Kähönen M, Lehtimäki T, Lang CC, Burkhardt R, Scholz M, Jukema JW, Eriksson N, Åkerblom A, James S, Held C, Hagström E, Spertus JA, Algra A, de Faire U, Åkesson A, Asselbergs FW, Patel RS, Leander K. PMID: 35812313; PMCID: PMC9260705.
      View in: PubMed   Mentions:
    24. Near-roadway air pollution, immune cells and adipokines among obese young adults. Environ Health. 2022 03 19; 21(1):36. Rahman MM, Liu FF, Eckel SP, Sankaranarayanan I, Shafiei-Jahani P, Howard E, Baronikian L, Sattler F, Lurmann FW, Allayee H, Akbari O, McConnell R. PMID: 35305663; PMCID: PMC8933931.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    25. Gene-Environment Interactions for Cardiovascular Disease. Curr Atheroscler Rep. 2021 10 14; 23(12):75. Hartiala JA, Hilser JR, Biswas S, Lusis AJ, Allayee H. PMID: 34648097; PMCID: PMC8903169.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    26. APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population. Elife. 2021 09 29; 10. Garcia AR, Finch C, Gatz M, Kraft T, Eid Rodriguez D, Cummings D, Charifson M, Buetow K, Beheim BA, Allayee H, Thomas GS, Stieglitz J, Gurven MD, Kaplan H, Trumble BC. PMID: 34586066; PMCID: PMC8480980.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    27. Noise Exposure and Distortion Product Otoacoustic Emission Suprathreshold Amplitudes: A Genome-Wide Association Study. Audiol Neurootol. 2021; 26(6):445-453. Lavinsky J, Kasperbauer G, Bento RF, Mendonça A, Wang J, Crow AL, Allayee H, Friedman RA. PMID: 34280920; PMCID: PMC8612944.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsPHPublic Health
    28. PNPLA3 Genotype, Arachidonic Acid Intake, and Unsaturated Fat Intake Influences Liver Fibrosis in Hispanic Youth with Obesity. Nutrients. 2021 May 12; 13(5). Jones RB, Arenaza L, Rios C, Plows JF, Berger PK, Alderete TL, Fogel JL, Nayak K, Mohamed P, Hwang D, Palmer S, Sinatra F, Allayee H, Kohli R, Goran MI. PMID: 34065978; PMCID: PMC8151324.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    29. Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. Eur Heart J. 2021 05 07; 42(18):1742-1756. Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee H, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James SK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Koenig W, Fliser D, Laufs U, Speer T, eQTLGen consortium, BIOS consortium. PMID: 33748830; PMCID: PMC8244638.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    30. CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation. Mucosal Immunol. 2021 07; 14(4):899-911. Shafiei-Jahani P, Helou DG, Hurrell BP, Galle-Treger L, Howard E, Quach C, Painter JD, Fung M, Lo R, Allayee H, Akbari O. PMID: 33731828; PMCID: PMC8225558.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    31. Genetic evidence for independent causal relationships between metabolic biomarkers and risk of coronary artery diseases. J Lipid Res. 2021; 62:100064. Allayee H. PMID: 33705740; PMCID: PMC8058558.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection. J Lipid Res. 2021; 62:100061. Hilser JR, Han Y, Biswas S, Gukasyan J, Cai Z, Zhu R, Tang WHW, Deb A, Lusis AJ, Hartiala JA, Allayee H. PMID: 33667465; PMCID: PMC7923911.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    33. Genome-wide analysis identifies novel susceptibility loci for myocardial infarction. Eur Heart J. 2021 03 01; 42(9):919-933. Hartiala JA, Han Y, Jia Q, Hilser JR, Huang P, Gukasyan J, Schwartzman WS, Cai Z, Biswas S, Trégouët DA, Smith NL, INVENT Consortium, CHARGE Consortium Hemostasis Working Group, GENIUS-CHD Consortium, Seldin M, Pan C, Mehrabian M, Lusis AJ, Bazeley P, Sun YV, Liu C, Quyyumi AA, Scholz M, Thiery J, Delgado GE, Kleber ME, März W, Howe LJ, Asselbergs FW, van Vugt M, Vlachojannis GJ, Patel RS, Lyytikäinen LP, Kähönen M, Lehtimäki T, Nieminen TVM, Kuukasjärvi P, Laurikka JO, Chang X, Heng CK, Jiang R, Kraus WE, Hauser ER, Ferguson JF, Reilly MP, Ito K, Koyama S, Kamatani Y, Komuro I, Biobank Japan, Stolze LK, Romanoski CE, Khan MD, Turner AW, Miller CL, Aherrahrou R, Civelek M, Ma L, Björkegren JLM, Kumar SR, Tang WHW, Hazen SL, Allayee H. PMID: 33532862; PMCID: PMC7936531.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCells
    34. Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression. Metabolism. 2021 03; 116:154457. Nimer N, Choucair I, Wang Z, Nemet I, Li L, Gukasyan J, Weeks TL, Alkhouri N, Zein N, Tang WHW, Fischbach MA, Brown JM, Allayee H, Dasarathy S, Gogonea V, Hazen SL. PMID: 33275980; PMCID: PMC7856026.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    35. The Genetics of Variation of the Wave 1 Amplitude of the Mouse Auditory Brainstem Response. J Assoc Res Otolaryngol. 2020 08; 21(4):323-336. Boussaty EC, Gillard D, Lavinsky J, Salehi P, Wang J, Mendonça A, Allayee H, Manor U, Friedman RA. PMID: 32757112; PMCID: PMC7445221.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCellsPHPublic Health
    36. Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data. Circulation. 2020 08 11; 142(6):546-555. Mahmoodi BK, Tragante V, Kleber ME, Holmes MV, Schmidt AF, McCubrey RO, Howe LJ, Direk K, Allayee H, Baranova EV, Braund PS, Delgado GE, Eriksson N, Gijsberts CM, Gong Y, Hartiala J, Heydarpour M, Pasterkamp G, Kotti S, Kuukasjärvi P, Lenzini PA, Levin D, Lyytikäinen LP, Muehlschlegel JD, Nelson CP, Nikus K, Pilbrow AP, Wilson Tang WH, van der Laan SW, van Setten J, Vilmundarson RO, Deanfield J, Deloukas P, Dudbridge F, James S, Mordi IR, Teren A, Bergmeijer TO, Body SC, Bots M, Burkhardt R, Cooper-DeHoff RM, Cresci S, Danchin N, Doughty RN, Grobbee DE, Hagström E, Hazen SL, Held C, Hoefer IE, Hovingh GK, Johnson JA, Kaczor MP, Kähönen M, Klungel OH, Laurikka JO, Lehtimäki T, Maitland-van der Zee AH, McPherson R, Palmer CN, Kraaijeveld AO, Pepine CJ, Sanak M, Sattar N, Scholz M, Simon T, Spertus JA, Stewart AFR, Szczeklik W, Thiery J, Visseren FLJ, Waltenberger J, Richards AM, Lang CC, Cameron VA, Åkerblom A, Pare G, März W, Samani NJ, Hingorani AD, Ten Berg JM, Wallentin L, Asselbergs FW, Patel RS. PMID: 32654539; PMCID: PMC7493828.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice. G3 (Bethesda). 2020 07 07; 10(7):2529-2541. Huda MN, VerHague M, Albright J, Smallwood T, Bell TA, Que E, Miller DR, Roshanravan B, Allayee H, Manuel de Villena FP, Bennett BJ. PMID: 32467129; PMCID: PMC7341122.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    38. Adult mouse hippocampal transcriptome changes associated with long-term behavioral and metabolic effects of gestational air pollution toxicity. Transl Psychiatry. 2020 07 07; 10(1):218. Haghani A, Johnson RG, Woodward NC, Feinberg JI, Lewis K, Ladd-Acosta C, Safi N, Jaffe AE, Sioutas C, Allayee H, Campbell DB, Volk HE, Finch CE, Morgan TE. PMID: 32636363; PMCID: PMC7341755.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCellsPHPublic Health
    39. Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma. Nat Commun. 2020 04 15; 11(1):1776. Han Y, Jia Q, Jahani PS, Hurrell BP, Pan C, Huang P, Gukasyan J, Woodward NC, Eskin E, Gilliland FD, Akbari O, Hartiala JA, Allayee H. PMID: 32296059; PMCID: PMC7160128.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansAnimalsCells
    40. Toxicity of urban air pollution particulate matter in developing and adult mouse brain: Comparison of total and filter-eluted nanoparticles. Environ Int. 2020 03; 136:105510. Haghani A, Johnson R, Safi N, Zhang H, Thorwald M, Mousavi A, Woodward NC, Shirmohammadi F, Coussa V, Wise JP, Forman HJ, Sioutas C, Allayee H, Morgan TE, Finch CE. PMID: 32004873; PMCID: PMC7063839.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsPHPublic Health
    41. A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity. PLoS Genet. 2019 12; 15(12):e1008528. Maazi H, Hartiala JA, Suzuki Y, Crow AL, Shafiei Jahani P, Lam J, Patel N, Rigas D, Han Y, Huang P, Eskin E, Lusis AJ, Gilliland FD, Akbari O, Allayee H. PMID: 31869344; PMCID: PMC6944376.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    42. Effect of ApoE4 Genotype on the Association Between Metabolic Phenotype and Subclinical Atherosclerosis in Postmenopausal Women. Am J Cardiol. 2019 10 01; 124(7):1031-1037. Sriprasert I, Mack WJ, Hodis HN, Allayee H, Brinton RD, Karim R. PMID: 31362877; PMCID: PMC6744988.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. Arterioscler Thromb Vasc Biol. 2019 06; 39(6):1045-1054. Shih DM, Zhu W, Schugar RC, Meng Y, Jia X, Miikeda A, Wang Z, Zieger M, Lee R, Graham M, Allayee H, Cantor RM, Mueller C, Brown JM, Hazen SL, Lusis AJ. PMID: 31070450; PMCID: PMC6531332.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    44. Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease. J Am Heart Assoc. 2019 05 21; 8(10):e011922. Jia Q, Han Y, Huang P, Woodward NC, Gukasyan J, Kettunen J, Ala-Korpela M, Anufrieva O, Wang Q, Perola M, Raitakari O, Lehtimäki T, Viikari J, Järvelin MR, Boehnke M, Laakso M, Mohlke KL, Fiehn O, Wang Z, Tang WHW, Hazen SL, Hartiala JA, Allayee H. PMID: 31070104; PMCID: PMC6585317.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
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    115. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar 06; 43(4):333-8. Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I, Cardiogenics, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J, CARDIoGRAM Consortium, Samani NJ. PMID: 21378990; PMCID: PMC3119261.
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    116. Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet. 2011 Feb 10; 7(2):e1001300. Lettre G, Palmer CD, Young T, Ejebe KG, Allayee H, Benjamin EJ, Bennett F, Bowden DW, Chakravarti A, Dreisbach A, Farlow DN, Folsom AR, Fornage M, Forrester T, Fox E, Haiman CA, Hartiala J, Harris TB, Hazen SL, Heckbert SR, Henderson BE, Hirschhorn JN, Keating BJ, Kritchevsky SB, Larkin E, Li M, Rudock ME, McKenzie CA, Meigs JB, Meng YA, Mosley TH, Newman AB, Newton-Cheh CH, Paltoo DN, Papanicolaou GJ, Patterson N, Post WS, Psaty BM, Qasim AN, Qu L, Rader DJ, Redline S, Reilly MP, Reiner AP, Rich SS, Rotter JI, Liu Y, Shrader P, Siscovick DS, Tang WH, Taylor HA, Tracy RP, Vasan RS, Waters KM, Wilks R, Wilson JG, Fabsitz RR, Gabriel SB, Kathiresan S, Boerwinkle E. PMID: 21347282; PMCID: PMC3037413.
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    117. Genetic contribution of the leukotriene pathway to coronary artery disease. Hum Genet. 2011 Jun; 129(6):617-27. Hartiala J, Li D, Conti DV, Vikman S, Patel Y, Tang WH, Brennan ML, Newman JW, Stephensen CB, Armstrong P, Hazen SL, Allayee H. PMID: 21293878; PMCID: PMC3092945.
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    118. ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation. J Lipid Res. 2011 May; 52(5):991-1003. Stephensen CB, Armstrong P, Newman JW, Pedersen TL, Legault J, Schuster GU, Kelley D, Vikman S, Hartiala J, Nassir R, Seldin MF, Allayee H. PMID: 21296957; PMCID: PMC3073473.
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    119. Genetic risk score and risk of myocardial infarction in Hispanics. Circulation. 2011 Feb 01; 123(4):374-80. Qi L, Ma J, Qi Q, Hartiala J, Allayee H, Campos H. PMID: 21242481; PMCID: PMC3076095.
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    120. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet. 2011 Jan 29; 377(9763):383-92. Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS, Myocardial Infarction Genetics Consortium, Wellcome Trust Case Control Consortium, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ. PMID: 21239051; PMCID: PMC3297116.
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    121. Inflammatory gene variants in the Tsimane, an indigenous Bolivian population with a high infectious load. Biodemography Soc Biol. 2011; 57(1):33-52. Vasunilashorn S, Finch CE, Crimmins EM, Vikman SA, Stieglitz J, Gurven M, Kaplan H, Allayee H. PMID: 21845926; PMCID: PMC3529658.
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    122. Increased hepatic fat in overweight Hispanic youth influenced by interaction between genetic variation in PNPLA3 and high dietary carbohydrate and sugar consumption. Am J Clin Nutr. 2010 Dec; 92(6):1522-7. Davis JN, Lê KA, Walker RW, Vikman S, Spruijt-Metz D, Weigensberg MJ, Allayee H, Goran MI. PMID: 20962157; PMCID: PMC2980971.
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    123. Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents. Diabetes. 2010 Dec; 59(12):3127-30. Goran MI, Walker R, Le KA, Mahurkar S, Vikman S, Davis JN, Spruijt-Metz D, Weigensberg MJ, Allayee H. PMID: 20852027; PMCID: PMC2992774.
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    124. A novel g.-1258G>A mutation in a conserved putative regulatory element of PAX9 is associated with autosomal dominant molar hypodontia. Clin Genet. 2011 Sep; 80(3):265-72. Mendoza-Fandino GA, Gee JM, Ben-Dor S, Gonzalez-Quevedo C, Lee K, Kobayashi Y, Hartiala J, Myers RM, Leal SM, Allayee H, Patel PI. PMID: 21443745; PMCID: PMC6240906.
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    125. Lipoprotein(a) levels and long-term cardiovascular risk in the contemporary era of statin therapy. J Lipid Res. 2010 Oct; 51(10):3055-61. Nicholls SJ, Tang WH, Scoffone H, Brennan DM, Hartiala J, Allayee H, Hazen SL. PMID: 20601648; PMCID: PMC2936758.
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    126. Polyunsaturated fatty acids and cardiovascular disease: implications for nutrigenetics. J Nutrigenet Nutrigenomics. 2009; 2(3):140-8. Allayee H, Roth N, Hodis HN. PMID: 19776641; PMCID: PMC2820567.
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    127. Additive effects of genetic variation in GCK and G6PC2 on insulin secretion and fasting glucose. Diabetes. 2009 Dec; 58(12):2946-53. Li X, Shu YH, Xiang AH, Trigo E, Kuusisto J, Hartiala J, Swift AJ, Kawakubo M, Stringham HM, Bonnycastle LL, Lawrence JM, Laakso M, Allayee H, Buchanan TA, Watanabe RM. PMID: 19741163; PMCID: PMC2780888.
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    128. Functional analysis of 5-lipoxygenase promoter repeat variants. Hum Mol Genet. 2009 Dec 01; 18(23):4521-9. Vikman S, Brena RM, Armstrong P, Hartiala J, Stephensen CB, Allayee H. PMID: 19717473; PMCID: PMC2773268.
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    129. Evidence for sex-specific associations between variation in acid phosphatase locus 1 (ACP1) and insulin sensitivity in Mexican-Americans. J Clin Endocrinol Metab. 2009 Oct; 94(10):4094-102. Shu YH, Hartiala J, Xiang AH, Trigo E, Lawrence JM, Allayee H, Buchanan TA, Bottini N, Watanabe RM. PMID: 19622628; PMCID: PMC2758733.
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    130. Genotyping the GGGCGG tandem repeat promoter polymorphism in the 5-lipoxygenase enzyme gene (ALOX5) by pyrosequencing assay. Genet Test Mol Biomarkers. 2009 Jun; 13(3):361-5. Schentrup AM, Allayee H, Lima JJ, Johnson JA, Langaee TY. PMID: 19473080; PMCID: PMC2998028.
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    131. Variation in IGF2BP2 interacts with adiposity to alter insulin sensitivity in Mexican Americans. Obesity (Silver Spring). 2009 Apr; 17(4):729-36. Li X, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA, Watanabe RM. PMID: 19148120; PMCID: PMC4357482.
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    132. A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus. Hum Mol Genet. 2009 Feb 01; 18(3):569-79. Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S, Italian Collaborative Group, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, Pons-Estel B, Alarcon-Riquelme ME, He Y, Zhang ZY, Allayee H, Chen XS, Martin J, Bottini N. PMID: 18981062; PMCID: PMC2722189.
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    133. Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. Am J Clin Nutr. 2008 Oct; 88(4):934-40. Allayee H, Baylin A, Hartiala J, Wijesuriya H, Mehrabian M, Lusis AJ, Campos H. PMID: 18842779; PMCID: PMC3014055.
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    134. Identification of ALOX5 as a gene regulating adiposity and pancreatic function. Diabetologia. 2008 Jun; 51(6):978-88. Mehrabian M, Schulthess FT, Nebohacova M, Castellani LW, Zhou Z, Hartiala J, Oberholzer J, Lusis AJ, Maedler K, Allayee H. PMID: 18421434; PMCID: PMC2835627.
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    135. Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease. Hum Genet. 2008 May; 123(4):399-408. Assimes TL, Knowles JW, Priest JR, Basu A, Volcik KA, Southwick A, Tabor HK, Hartiala J, Allayee H, Grove ML, Tabibiazar R, Sidney S, Fortmann SP, Go A, Hlatky M, Iribarren C, Boerwinkle E, Myers R, Risch N, Quertermous T. PMID: 18369664; PMCID: PMC4023692.
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    136. Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk. JAMA. 2008 Mar 19; 299(11):1265-76. Bhattacharyya T, Nicholls SJ, Topol EJ, Zhang R, Yang X, Schmitt D, Fu X, Shao M, Brennan DM, Ellis SG, Brennan ML, Allayee H, Lusis AJ, Hazen SL. PMID: 18349088; PMCID: PMC3014051.
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    137. Allgrove syndrome in a Mexican American family is caused by an ancestral mutation derived from North Africa. Clin Genet. 2008 Apr; 73(4):385-7. Chang AJ, Kline MM, Currie Y, Perez MO, Hartiala J, Wijesuriya H, Buchanan TA, Watanabe RM, Allayee H. PMID: 18261130.
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    138. Prevalence of common disease-associated variants in Asian Indians. BMC Genet. 2008 Feb 04; 9:13. Pemberton TJ, Mehta NU, Witonsky D, Di Rienzo A, Allayee H, Conti DV, Patel PI. PMID: 18248681; PMCID: PMC2267478.
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    139. Non-conventional genetic risk factors for cardiovascular disease. World Rev Nutr Diet. 2008; 98:62-76. Allayee H. PMID: 18806462.
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    140. Evidence of interaction between PPARG2 and HNF4A contributing to variation in insulin sensitivity in Mexican Americans. Diabetes. 2008 Apr; 57(4):1048-56. Black MH, Fingerlin TE, Allayee H, Zhang W, Xiang AH, Trigo E, Hartiala J, Lehtinen AB, Haffner SM, Bergman RN, McEachin RC, Kjos SL, Lawrence JM, Buchanan TA, Watanabe RM. PMID: 18162503; PMCID: PMC4447520.
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    141. FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice. Toxicol Sci. 2007 Dec; 100(2):474-85. Martin LJ, Chen H, Liao X, Allayee H, Shih DM, Lee GS, Hovland DN, Robbins WA, Carnes K, Hess RA, Lusis AJ, Collins MD. PMID: 17785681.
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    142. The effect of montelukast and low-dose theophylline on cardiovascular disease risk factors in asthmatics. Chest. 2007 Sep; 132(3):868-74. Allayee H, Hartiala J, Lee W, Mehrabian M, Irvin CG, Conti DV, Lima JJ. PMID: 17646220.
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    143. Genetics of gestational diabetes mellitus and type 2 diabetes. Diabetes Care. 2007 Jul; 30 Suppl 2:S134-40. Watanabe RM, Black MH, Xiang AH, Allayee H, Lawrence JM, Buchanan TA. PMID: 17596461; PMCID: PMC2925642.
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    144. Transcription factor 7-like 2 (TCF7L2) is associated with gestational diabetes mellitus and interacts with adiposity to alter insulin secretion in Mexican Americans. Diabetes. 2007 May; 56(5):1481-5. Watanabe RM, Allayee H, Xiang AH, Trigo E, Hartiala J, Lawrence JM, Buchanan TA. PMID: 17317761; PMCID: PMC2925638.
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    145. A new locus for autosomal dominant amelogenesis imperfecta on chromosome 8q24.3. Hum Genet. 2007 Jan; 120(5):653-62. Mendoza G, Pemberton TJ, Lee K, Scarel-Caminaga R, Mehrian-Shai R, Gonzalez-Quevedo C, Ninis V, Hartiala J, Allayee H, Snead ML, Leal SM, Line SR, Patel PI. PMID: 17024372; PMCID: PMC6174526.
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    146. Effect of obesity on clinical presentation and response to treatment in asthma. J Asthma. 2006 Sep; 43(7):553-8. Dixon AE, Shade DM, Cohen RI, Skloot GS, Holbrook JT, Smith LJ, Lima JJ, Allayee H, Irvin CG, Wise RA, American Lung Association-Asthma Clinical Research Centers. PMID: 16939998.
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    147. Using inbred mouse strains to identify genes for complex diseases. Front Biosci. 2006 May 01; 11:1216-26. Allayee H, Andalibi A, Mehrabian M. PMID: 16368507.
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    148. Nonconventional genetic risk factors for cardiovascular disease. Curr Atheroscler Rep. 2006 May; 8(3):184-92. Tymchuk CN, Hartiala J, Patel PI, Mehrabian M, Allayee H. PMID: 16640955.
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    149. Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Am J Respir Crit Care Med. 2006 Feb 15; 173(4):379-85. Lima JJ, Zhang S, Grant A, Shao L, Tantisira KG, Allayee H, Wang J, Sylvester J, Holbrook J, Wise R, Weiss ST, Barnes K. PMID: 16293801; PMCID: PMC2662939.
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    150. Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits. Nat Genet. 2005 Nov; 37(11):1224-33. Mehrabian M, Allayee H, Stockton J, Lum PY, Drake TA, Castellani LW, Suh M, Armour C, Edwards S, Lamb J, Lusis AJ, Schadt EE. PMID: 16200066.
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    151. A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. Genomics. 2005 Sep; 86(3):259-70. Davis RC, Schadt EE, Smith DJ, Hsieh EW, Cervino AC, van Nas A, Rosales M, Doss S, Meng H, Allayee H, Lusis AJ. PMID: 16039824.
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    152. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet. 2004 Nov; 36(11):1133-7. Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'Hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpää MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F, Complex Trait Consortium. PMID: 15514660.
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    153. Vascular cross-talk: a conversation. Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1748-9. Mehrabian M, Allayee H. PMID: 15472137.
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    154. Quantitative trait loci for apolipoprotein B, cholesterol, and triglycerides in familial combined hyperlipidemia pedigrees. Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1935-41. Cantor RM, de Bruin T, Kono N, Napier S, van Nas A, Allayee H, Lusis AJ. PMID: 15308552.
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    155. Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ Res. 2004 Apr 16; 94(7):993-9. Mar R, Pajukanta P, Allayee H, Groenendijk M, Dallinga-Thie G, Krauss RM, Sinsheimer JS, Cantor RM, de Bruin TW, Lusis AJ. PMID: 15001527.
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    156. Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis. N Engl J Med. 2004 Jan 01; 350(1):29-37. Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, Mar R, Lusis AJ, Mehrabian M. PMID: 14702425.
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    157. 5-lipoxygenase and atherosclerosis. Curr Opin Lipidol. 2003 Oct; 14(5):447-57. Mehrabian M, Allayee H. PMID: 14501583.
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    158. Using mice to dissect genetic factors in atherosclerosis. Arterioscler Thromb Vasc Biol. 2003 Sep 01; 23(9):1501-9. Allayee H, Ghazalpour A, Lusis AJ. PMID: 12920046.
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    159. Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia. Circ Res. 2003 Jun 13; 92(11):1262-7. Allayee H, Castellani LW, Cantor RM, de Bruin TW, Lusis AJ. PMID: 12738753.
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    160. Combined analysis of genome scans of dutch and finnish families reveals a susceptibility locus for high-density lipoprotein cholesterol on chromosome 16q. Am J Hum Genet. 2003 Apr; 72(4):903-17. Pajukanta P, Allayee H, Krass KL, Kuraishy A, Soro A, Lilja HE, Mar R, Taskinen MR, Nuotio I, Laakso M, Rotter JI, de Bruin TW, Cantor RM, Lusis AJ, Peltonen L. PMID: 12638083; PMCID: PMC1180353.
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    161. Identification of 5-lipoxygenase as a major gene contributing to atherosclerosis susceptibility in mice. Circ Res. 2002 Jul 26; 91(2):120-6. Mehrabian M, Allayee H, Wong J, Shi W, Wang XP, Shaposhnik Z, Funk CD, Lusis AJ, Shih W. PMID: 12142344.
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    162. Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circ Res. 2002 May 03; 90(8):926-31. Allayee H, Krass KL, Pajukanta P, Cantor RM, van der Kallen CJ, Mar R, Rotter JI, de Bruin TW, Peltonen L, Lusis AJ. PMID: 11988495.
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    163. Understanding atherosclerosis through mouse genetics. Curr Opin Lipidol. 2002 Apr; 13(2):181-9. Sheth SS, Deluna A, Allayee H, Lusis AJ. PMID: 11891421.
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    164. Genome scan for blood pressure in Dutch dyslipidemic families reveals linkage to a locus on chromosome 4p. Hypertension. 2001 Oct; 38(4):773-8. Allayee H, de Bruin TW, Michelle Dominguez K, Cheng LS, Ipp E, Cantor RM, Krass KL, Keulen ET, Aouizerat BE, Lusis AJ, Rotter JI. PMID: 11641285.
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    165. Biochemistry. An absorbing study of cholesterol. Science. 2000 Dec 01; 290(5497):1709-11. Allayee H, Laffitte BA, Lusis AJ. PMID: 11186392.
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    166. Genome scan for adiposity in Dutch dyslipidemic families reveals novel quantitative trait loci for leptin, body mass index and soluble tumor necrosis factor receptor superfamily 1A. Int J Obes Relat Metab Disord. 2000 Nov; 24(11):1381-91. van der Kallen CJ, Cantor RM, van Greevenbroek MM, Geurts JM, Bouwman FG, Aouizerat BE, Allayee H, Buurman WA, Lusis AJ, Rotter JI, de Bruin TW. PMID: 11126332.
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    167. Identification of TNFRSF1B as a novel modifier gene in familial combined hyperlipidemia. Hum Mol Genet. 2000 Sep 01; 9(14):2067-74. Geurts JM, Janssen RG, van Greevenbroek MM, van der Kallen CJ, Cantor RM, Bu X, Aouizerat BE, Allayee H, Rotter JI, de Bruin TW. PMID: 10958645.
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    168. A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2. J Lipid Res. 2000 Apr; 41(4):573-82. Mouzeyan A, Choi J, Allayee H, Wang X, Sinsheimer J, Phan J, Castellani LW, Reue K, Lusis AJ, Davis RC. PMID: 10744778.
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    169. Contribution of the hepatic lipase gene to the atherogenic lipoprotein phenotype in familial combined hyperlipidemia. J Lipid Res. 2000 Feb; 41(2):245-52. Allayee H, Dominguez KM, Aouizerat BE, Krauss RM, Rotter JI, Lu J, Cantor RM, de Bruin TW, Lusis AJ. PMID: 10681408.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    170. Linkage of a candidate gene locus to familial combined hyperlipidemia: lecithin:cholesterol acyltransferase on 16q. Arterioscler Thromb Vasc Biol. 1999 Nov; 19(11):2730-6. Aouizerat BE, Allayee H, Cantor RM, Dallinga-Thie GM, Lanning CD, de Bruin TW, Lusis AJ, Rotter JI. PMID: 10559018.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    171. A genome scan for familial combined hyperlipidemia reveals evidence of linkage with a locus on chromosome 11. Am J Hum Genet. 1999 Aug; 65(2):397-412. Aouizerat BE, Allayee H, Cantor RM, Davis RC, Lanning CD, Wen PZ, Dallinga-Thie GM, de Bruin TW, Rotter JI, Lusis AJ. PMID: 10417282; PMCID: PMC1377938.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    172. Novel genes for familial combined hyperlipidemia. Curr Opin Lipidol. 1999 Apr; 10(2):113-22. Aouizerat BE, Allayee H, Bodnar J, Krass KL, Peltonen L, de Bruin TW, Rotter JI, Lusis AJ. PMID: 10327279.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    173. Families with familial combined hyperlipidemia and families enriched for coronary artery disease share genetic determinants for the atherogenic lipoprotein phenotype. Am J Hum Genet. 1998 Aug; 63(2):577-85. Allayee H, Aouizerat BE, Cantor RM, Dallinga-Thie GM, Krauss RM, Lanning CD, Rotter JI, Lusis AJ, de Bruin TW. PMID: 9683614; PMCID: PMC1377323.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    174. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J Clin Invest. 1994 Aug; 94(2):877-84. Liao F, Andalibi A, Qiao JH, Allayee H, Fogelman AM, Lusis AJ. PMID: 8040344; PMCID: PMC296170.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
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