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Tishya A.l. Wren, PhD

TitleAssociate Professor of Research Orthopaedic Surgery and Radiology
InstitutionUniversity of Southern California
DepartmentPediatric Orthopaedic
AddressCHL 4650 Sunset Blvd
Off Campus
Los Angeles CA 90027
Phone+1 323 361 4120
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    Collapse Biography 
    Collapse Awards and Honors
    American Academy of Orthopaedic Surgeons2015Best Paper Award - Pediatrics
    Gait and Clinical Movement Analysis Society2014Best Paper Award
    Pediatric Orthopaedic Society of North America2004Marc A. Asher Clinical Scientific Paper Award
    1992National Science Foundation Graduate Fellowship
    Amherst College1992Woods-Travis Valedictorian Award

    Collapse Overview 
    Collapse Overview
    Dr. Wren is a biomedical engineer working in clinical environment. As Director of Research for the Children's Orthopaedic Center at Children's Hospital Los Angeles, Dr. Wren conducts clinical and basic research in several different areas of orthopaedics. Two of the primary areas are (1) evaluation and treatment of movement abnormalities in children with neurologic deficits and (2) assessment of bone and fractures in children. This research is carried out in collaboration with colleagues in the John C. Wilson, Jr. Motion Analysis Laboratory and the Children's Imaging Research Program.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Chadwick KP, Mueske NM, Horenstein RE, Shefelbine SJ, Wren T. Children with myelomeningocele do not exhibit normal remodeling of tibia roundness with physical development. Bone. 2018 Jul 04; 114:292-297. PMID: 29991457.
      View in: PubMed
    2. Solomito MJ, Kostyun RO, Wu YH, Mueske NM, Wren T, Chou LS, Ounpuu S. Motion analysis evaluation of adolescent athletes during dual-task walking following a concussion: A multicenter study. Gait Posture. 2018 Jun 25; 64:260-265. PMID: 29966907.
      View in: PubMed
    3. Gilsanz V, Wren T, Ponrartana S, Mora S, Rosen CJ. Sexual Dimorphism and the Origins of Human Spinal Health. Endocr Rev. 2018 Apr 01; 39(2):221-239. PMID: 29385433.
      View in: PubMed
    4. Wren T, Mueske NM, Brophy CH, Pace JL, Katzel MJ, Edison BR, VandenBerg CD, Zaslow TL. Hop Distance Symmetry Does Not Indicate Normal Landing Biomechanics in Adolescent Athletes With Recent Anterior Cruciate Ligament Reconstruction. J Orthop Sports Phys Ther. 2018 Mar 30; 1-23. PMID: 29602303.
      View in: PubMed
    5. Poorghasamians E, Aggabao PC, Wren T, Ponrartana S, Gilsanz V. Vertebral cross-sectional growth: A predictor of vertebral wedging in the immature skeleton. PLoS One. 2017; 12(12):e0190225. PMID: 29281728.
      View in: PubMed
    6. Roiz R, Mueske NM, Van Speybroeck A, Ryan DD, Gilsanz V, Wren T. Advanced skeletal maturity in children and adolescents with myelomeningocele. J Pediatr Rehabil Med. 2017 Dec 11; 10(3-4):283-293. PMID: 29125519.
      View in: PubMed
    7. Wren T, Ponrartana S, Aggabao PC, Poorghasamians E, Skaggs DL, Gilsanz V. Increased Lumbar Lordosis and Smaller Vertebral Cross-sectional Area are Associated with Spondylolysis. Spine (Phila Pa 1976). 2017 Oct 31. PMID: 29095410.
      View in: PubMed
    8. Wren T, Ponrartana S, Aggabao PC, Poorghasamians E, Gilsanz V. Association Between Vertebral Cross-sectional Area and Vertebral Wedging in Children and Adolescents: A Cross-sectional Analysis. J Bone Miner Res. 2017 Nov; 32(11):2257-2262. PMID: 28667786.
      View in: PubMed
    9. Wren T, Ponrartana S, Poorghasamians E, Moreau S, Aggabao PC, Zaslow TL, Edison BR, Gilsanz V. Biomechanical Modeling of Spine Flexibility and Its Relationship to Spinal Range of Motion and Idiopathic Scoliosis. Spine Deform. 2017 Jul; 5(4):225-230. PMID: 28622896.
      View in: PubMed
    10. Borish CN, Mueske NM, Wren T. A comparison of three methods of measuring tibial torsion in children with myelomeningocele and normally developing children. Clin Anat. 2017 Nov; 30(8):1043-1048. PMID: 28470694.
      View in: PubMed
    11. Sousa TC, Nazareth A, Rethlefsen SA, Mueske NM, Wren T, Kay RM. Rectus Femoris Transfer Surgery Worsens Crouch Gait in Children With Cerebral Palsy at GMFCS Levels III and IV. J Pediatr Orthop. 2017 Apr 03. PMID: 28375967.
      View in: PubMed
    12. Wren T, Aggabao PC, Poorghasamians E, Chavez TA, Ponrartana S, Gilsanz V. Association between vertebral cross-sectional area and lumbar lordosis angle in adolescents. PLoS One. 2017; 12(2):e0172844. PMID: 28245271.
      View in: PubMed
    13. Orgel E, Mueske NM, Sposto R, Gilsanz V, Wren T, Freyer DR, Butturini AM, Mittelman SD. A randomized controlled trial testing an adherence-optimized Vitamin D regimen to mitigate bone change in adolescents being treated for acute lymphoblastic leukemia. Leuk Lymphoma. 2017 Oct; 58(10):2370-2378. PMID: 28278717.
      View in: PubMed
    14. Nazareth A, Rethlefsen S, Sousa TC, Mueske NM, Wren T, Kay RM. Percutaneous Hamstring Lengthening Surgery is as Effective as Open Lengthening in Children With Cerebral Palsy. J Pediatr Orthop. 2016 Dec 22. PMID: 28009799.
      View in: PubMed
    15. Gordon CM, Zemel BS, Wren T, Leonard MB, Bachrach LK, Rauch F, Gilsanz V, Rosen CJ, Winer KK. The Determinants of Peak Bone Mass. J Pediatr. 2017 Jan; 180:261-269. PMID: 27816219.
      View in: PubMed
    16. Choi H, Wren T, Steele KM. Gastrocnemius operating length with ankle foot orthoses in cerebral palsy. Prosthet Orthot Int. 2017 Jun; 41(3):274-285. PMID: 27613590.
      View in: PubMed
    17. Nazareth A, Mueske NM, Wren T. Effect of Tibia Marker Placement on Kinematics in Pathological Gait. J Appl Biomech. 2016 Dec; 32(6):603-607. PMID: 27619915.
      View in: PubMed
    18. Rethlefsen SA, Blumstein G, Kay RM, Dorey F, Wren T. Prevalence of specific gait abnormalities in children with cerebral palsy revisited: influence of age, prior surgery, and Gross Motor Function Classification System level. Dev Med Child Neurol. 2017 01; 59(1):79-88. PMID: 27421715.
      View in: PubMed
    19. Yasmeh P, Mueske NM, Yasmeh S, Ryan DD, Wren T. Walking activity during daily living in children with myelomeningocele. Disabil Rehabil. 2017 07; 39(14):1422-1427. PMID: 27384911.
      View in: PubMed
    20. Ponrartana S, Fisher CL, Aggabao PC, Chavez TA, Broom AM, Wren T, Skaggs DL, Gilsanz V. Small vertebral cross-sectional area and tall intervertebral disc in adolescent idiopathic scoliosis. Pediatr Radiol. 2016 Sep; 46(10):1424-9. PMID: 27183842.
      View in: PubMed
    21. Lorenzana DJ, Mueske NM, Ryan DD, Van Speybroeck AL, Wren T. Quantitative Analysis of Lower Leg Adipose Tissue Distribution in Youth with Myelomeningocele. J Child Neurol. 2016 07; 31(8):979-84. PMID: 26961265; PMCID: PMC4925233 [Available on 07/01/17].
    22. Ryan DD, Lightdale-Miric NR, Joiner ER, Wren T, Spragg L, Heffernan MJ, Kay RM, Skaggs DL. Variability of the Anterior Humeral Line in Normal Pediatric Elbows. J Pediatr Orthop. 2016 Mar; 36(2):e14-6. PMID: 26035494.
      View in: PubMed
    23. Zaslow TL, Pace JL, Mueske NM, Chua MC, Katzel MJ, Dennis SW, Wren T. Comparison of lateral shuffle and side-step cutting in young recreational athletes. Gait Posture. 2016 Feb; 44:189-93. PMID: 27004656.
      View in: PubMed
    24. Van Speybroeck A, Mueske NM, Mittelman SD, Kremer RK, Ryan DD, Wren T. Fasting serum blood measures of bone and lipid metabolism in children with myelomeningocele for early detection of cardiovascular and bone fragility risk factors. J Spinal Cord Med. 2017 03; 40(2):193-200. PMID: 26666357.
      View in: PubMed
    25. Rethlefsen SA, Nguyen DT, Wren T, Milewski MD, Kay RM. Knee Pain and Patellofemoral Symptoms in Patients With Cerebral Palsy. J Pediatr Orthop. 2015 Jul-Aug; 35(5):519-22. PMID: 25171680.
      View in: PubMed
    26. Wren T. Assessing bone accrual in cerebral palsy: new longitudinal data and future needs. Dev Med Child Neurol. 2015 Nov; 57(11):990-1. PMID: 25951373.
      View in: PubMed
    27. Horenstein RE, Shefelbine SJ, Mueske NM, Fisher CL, Wren T. An approach for determining quantitative measures for bone volume and bone mass in the pediatric spina bifida population. Clin Biomech (Bristol, Avon). 2015 Aug; 30(7):748-54. PMID: 26002057; PMCID: PMC4523422.
    28. Yu S, Rethlefsen SA, Wren T, Kay RM. Long-term ambulatory change after lower extremity orthopaedic surgery in children with cerebral palsy: a retrospective review. J Pediatr Orthop. 2015 Apr-May; 35(3):285-9. PMID: 24978124.
      View in: PubMed
    29. Wren T, Dryden JW, Mueske NM, Dennis SW, Healy BS, Rethlefsen SA. Comparison of 2 Orthotic Approaches in Children With Cerebral Palsy. Pediatr Phys Ther. 2015; 27(3):218-26. PMID: 26035652.
      View in: PubMed
    30. Lightdale-Miric N, Mueske NM, Lawrence EL, Loiselle J, Berggren J, Dayanidhi S, Stevanovic M, Valero-Cuevas FJ, Wren T. Long term functional outcomes after early childhood pollicization. J Hand Ther. 2015 Apr-Jun; 28(2):158-65; quiz 166. PMID: 25835252; PMCID: PMC4424177.
    31. Stebbins J, Trinler UK, Baker R, Brunner R, Wren T, Theologis T. Recommendations for reporting gait studies. Gait Posture. 2015 Feb; 41(2):339-40. PMID: 25497141.
      View in: PubMed
    32. Ramirez RN, Ryan DD, Williams J, Wren T, Ibrahim D, Weiss JM, Kay RM, Lightdale-Miric N, Skaggs DL. A line drawn along the radial shaft misses the capitellum in 16% of radiographs of normal elbows. J Pediatr Orthop. 2014 Dec; 34(8):763-7. PMID: 24787305.
      View in: PubMed
    33. Mueske NM, Ryan DD, Van Speybroeck AL, Chan LS, Wren T. Fat distribution in children and adolescents with myelomeningocele. Dev Med Child Neurol. 2015 Mar; 57(3):273-8. PMID: 25251828; PMCID: PMC4323886.
    34. Ponrartana S, Ramos-Platt L, Wren T, Hu HH, Perkins TG, Chia JM, Gilsanz V. Effectiveness of diffusion tensor imaging in assessing disease severity in Duchenne muscular dystrophy: preliminary study. Pediatr Radiol. 2015 Apr; 45(4):582-9. PMID: 25246097.
      View in: PubMed
    35. Lightdale-Miric N, Mueske NM, Dayanidhi S, Loiselle J, Berggren J, Lawrence EL, Stevanovic M, Valero-Cuevas FJ, Wren T. Quantitative assessment of dynamic control of fingertip forces after pollicization. Gait Posture. 2015 Jan; 41(1):1-6. PMID: 25262333; PMCID: PMC4267977.
    36. Ponrartana S, Andrade KE, Wren T, Ramos-Platt L, Hu HH, Bluml S, Gilsanz V. Repeatability of chemical-shift-encoded water-fat MRI and diffusion-tensor imaging in lower extremity muscles in children. AJR Am J Roentgenol. 2014 Jun; 202(6):W567-73. PMID: 24848851.
      View in: PubMed
    37. Franklin CC, Wren T, Ferkel E, Arkader A. Predictors of conversion from conservative to operative treatment of pediatric forearm fractures. J Pediatr Orthop B. 2014 Mar; 23(2):150-4. PMID: 24322534.
      View in: PubMed
    38. Milewski MD, Skaggs DL, Bishop GA, Pace JL, Ibrahim DA, Wren T, Barzdukas A. Chronic lack of sleep is associated with increased sports injuries in adolescent athletes. J Pediatr Orthop. 2014 Mar; 34(2):129-33. PMID: 25028798.
      View in: PubMed
    39. Wren T, Kalkwarf HJ, Zemel BS, Lappe JM, Oberfield S, Shepherd JA, Winer KK, Gilsanz V. Longitudinal tracking of dual-energy X-ray absorptiometry bone measures over 6 years in children and adolescents: persistence of low bone mass to maturity. J Pediatr. 2014 Jun; 164(6):1280-5.e2. PMID: 24485819.
      View in: PubMed
    40. Wren T, Ponrartana S, Van Speybroeck A, Ryan DD, Chia JM, Hu HH. Heterogeneity of muscle fat infiltration in children with spina bifida. Res Dev Disabil. 2014 Jan; 35(1):215-22. PMID: 24169376; PMCID: PMC3873476.
    41. Rethlefsen SA, Yasmeh S, Wren T, Kay RM. Repeat hamstring lengthening for crouch gait in children with cerebral palsy. J Pediatr Orthop. 2013 Jul-Aug; 33(5):501-4. PMID: 23752146.
      View in: PubMed
    42. Wren T, Lening C, Rethlefsen SA, Kay RM. Impact of gait analysis on correction of excessive hip internal rotation in ambulatory children with cerebral palsy: a randomized controlled trial. Dev Med Child Neurol. 2013 Oct; 55(10):919-25. PMID: 23738949.
      View in: PubMed
    43. Mueske NM, Chan LS, Wren T. Reliability of lateral distal femur dual-energy X-ray absorptiometry measures. J Clin Densitom. 2014 Oct-Dec; 17(4):522-7. PMID: 23541123; PMCID: PMC3742591.
    44. Wren T, Otsuka NY, Bowen RE, Scaduto AA, Chan LS, Dennis SW, Rethlefsen SA, Healy BS, Hara R, Sheng M, Kay RM. Outcomes of lower extremity orthopedic surgery in ambulatory children with cerebral palsy with and without gait analysis: results of a randomized controlled trial. Gait Posture. 2013 Jun; 38(2):236-41. PMID: 23219787.
      View in: PubMed
    45. Wren T, Shepherd JA, Kalkwarf HJ, Zemel BS, Lappe JM, Oberfield S, Dorey FJ, Winer KK, Gilsanz V. Racial disparity in fracture risk between white and nonwhite children in the United States. J Pediatr. 2012 Dec; 161(6):1035-40. PMID: 22974572; PMCID: PMC3504618.
    46. Wren T, Elihu KJ, Mansour S, Rethlefsen SA, Ryan DD, Smith ML, Kay RM. Differences in implementation of gait analysis recommendations based on affiliation with a gait laboratory. Gait Posture. 2013 Feb; 37(2):206-9. PMID: 22871237.
      View in: PubMed
    47. Ponrartana S, Aggabao PC, Hu HH, Aldrovandi GM, Wren T, Gilsanz V. Brown adipose tissue and its relationship to bone structure in pediatric patients. J Clin Endocrinol Metab. 2012 Aug; 97(8):2693-8. PMID: 22593587; PMCID: PMC3410267.
    48. Huh K, Rethlefsen SA, Wren T, Kay RM. Surgical management of hip subluxation and dislocation in children with cerebral palsy: isolated VDRO or combined surgery? J Pediatr Orthop. 2011 Dec; 31(8):858-63. PMID: 22101664.
      View in: PubMed
    49. Gilsanz V, Smith ML, Goodarzian F, Kim M, Wren T, Hu HH. Changes in brown adipose tissue in boys and girls during childhood and puberty. J Pediatr. 2012 Apr; 160(4):604-609.e1. PMID: 22048045; PMCID: PMC3307823.
    50. Aisen ML, Kerkovich D, Mast J, Mulroy S, Wren T, Kay RM, Rethlefsen SA. Cerebral palsy: clinical care and neurological rehabilitation. Lancet Neurol. 2011 Sep; 10(9):844-52. PMID: 21849165.
      View in: PubMed
    51. Wren T, Otsuka NY, Bowen RE, Scaduto AA, Chan LS, Sheng M, Hara R, Kay RM. Influence of gait analysis on decision-making for lower extremity orthopaedic surgery: Baseline data from a randomized controlled trial. Gait Posture. 2011 Jul; 34(3):364-9. PMID: 21723131.
      View in: PubMed
    52. Wren T, Gorton GE, Ounpuu S, Tucker CA. Efficacy of clinical gait analysis: A systematic review. Gait Posture. 2011 Jun; 34(2):149-53. PMID: 21646022.
      View in: PubMed
    53. Wren T, Chung SA, Dorey FJ, Bluml S, Adams GB, Gilsanz V. Bone marrow fat is inversely related to cortical bone in young and old subjects. J Clin Endocrinol Metab. 2011 Mar; 96(3):782-6. PMID: 21177790.
      View in: PubMed
    54. Al Wren T, Lee DC, Kay RM, Dorey FJ, Gilsanz V. Bone density and size in ambulatory children with cerebral palsy. Dev Med Child Neurol. 2011 Feb; 53(2):137-41. PMID: 21166671; PMCID: PMC3064513.
    55. Wren T, Lee DC, Hara R, Rethlefsen SA, Kay RM, Dorey FJ, Gilsanz V. Effect of high-frequency, low-magnitude vibration on bone and muscle in children with cerebral palsy. J Pediatr Orthop. 2010 Oct-Nov; 30(7):732-8. PMID: 20864862; PMCID: PMC2946103.
    56. Rethlefsen SA, Lening C, Wren T, Kay RM. Excessive hip flexion during gait in patients with static encephalopathy: an examination of contributing factors. J Pediatr Orthop. 2010 Sep; 30(6):562-7. PMID: 20733421.
      View in: PubMed
    57. Gilsanz V, Chalfant J, Kalkwarf H, Zemel B, Lappe J, Oberfield S, Shepherd J, Wren T, Winer K. Age at onset of puberty predicts bone mass in young adulthood. J Pediatr. 2011 Jan; 158(1):100-5, 105.e1-2. PMID: 20797727; PMCID: PMC4767165.
    58. Wren T, Cheatwood AP, Rethlefsen SA, Hara R, Perez FJ, Kay RM. Achilles tendon length and medial gastrocnemius architecture in children with cerebral palsy and equinus gait. J Pediatr Orthop. 2010 Jul-Aug; 30(5):479-84. PMID: 20574267.
      View in: PubMed
    59. Di Iorgi N, Mo AO, Grimm K, Wren T, Dorey F, Gilsanz V. Bone acquisition in healthy young females is reciprocally related to marrow adiposity. J Clin Endocrinol Metab. 2010 Jun; 95(6):2977-82. PMID: 20392872; PMCID: PMC2902071.
    60. Huh K, Rethlefsen SA, Wren T, Kay RM. Development of calcaneal gait without prior triceps surae lengthening: an examination of predictive factors. J Pediatr Orthop. 2010 Apr-May; 30(3):240-3. PMID: 20357589.
      View in: PubMed
    61. Bernthal NM, Gamradt SC, Kay RM, Wren T, Cuomo AV, Reid J, Bales J, Otsuka NY. Static and dynamic gait parameters before and after multilevel soft tissue surgery in ambulating children with cerebral palsy. J Pediatr Orthop. 2010 Mar; 30(2):174-9. PMID: 20179566.
      View in: PubMed
    62. Gilsanz V, Kremer A, Mo AO, Wren T, Kremer R. Vitamin D status and its relation to muscle mass and muscle fat in young women. J Clin Endocrinol Metab. 2010 Apr; 95(4):1595-601. PMID: 20164290; PMCID: PMC2853984.
    63. Wren T, Gilsanz V. Evolving role of imaging in the evaluation of bone structure. J Bone Miner Res. 2009 Dec; 24(12):1943-5. PMID: 19839775.
      View in: PubMed
    64. Skaggs DL, Sankar WN, Albrektson J, Wren T, Campbell RM. Weight gain following vertical expandable prosthetic titanium ribs surgery in children with thoracic insufficiency syndrome. Spine (Phila Pa 1976). 2009 Nov 01; 34(23):2530-3. PMID: 19927103.
      View in: PubMed
    65. Wren T, Kalisvaart MM, Ghatan CE, Rethlefsen SA, Hara R, Sheng M, Chan LS, Kay RM. Effects of preoperative gait analysis on costs and amount of surgery. J Pediatr Orthop. 2009 Sep; 29(6):558-63. PMID: 19700983.
      View in: PubMed
    66. Lee DC, Campbell PP, Gilsanz V, Wren T. Contribution of the vertebral posterior elements in anterior-posterior DXA spine scans in young subjects. J Bone Miner Res. 2009 Aug; 24(8):1398-403. PMID: 19257831; PMCID: PMC3276347.
    67. Wren T, Engsberg JR. Normalizing lower extremity strength data for children, adolescents, and young adults with cerebral palsy. J Appl Biomech. 2009 Aug; 25(3):195-202. PMID: 19827468.
      View in: PubMed
    68. Rethlefsen SA, Kam G, Wren T, Kay RM. Predictors of outcome of distal rectus femoris transfer surgery in ambulatory children with cerebral palsy. J Pediatr Orthop B. 2009 Mar; 18(2):58-62. PMID: 19282786.
      View in: PubMed
    69. Wren T, Chen AY, Wang VJ, Claudius IA, Skaggs DL. Prior treatment of fracture patients in a tertiary pediatric emergency department: informal referrals from other emergency departments. J Pediatr Orthop. 2009 Mar; 29(2):137-41. PMID: 19352238.
      View in: PubMed
    70. Engsberg JR, Tucker C, Ounpuu S, Wren T, Sisto SA, Kaufman KR. Gait and clinical movement analysis research priorities: 2007 update from the research committee of the Gait and Clinical Movement Analysis Society. Gait Posture. 2009 Feb; 29(2):169-71. PMID: 19135373.
      View in: PubMed
    71. Yu GY, Yan CH, Yu XG, Zuo Y, Zou XY, Xu J, Wu SH, Shen XM. [Effects of chelation therapy with succimer in young rabbits of moderate lead poisoning]. Zhonghua Yu Fang Yi Xue Za Zhi. 2009 Jan; 43(1):8-13. PMID: 19534872.
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    72. Gilsanz V, Perez FJ, Campbell PP, Dorey FJ, Lee DC, Wren T. Quantitative CT reference values for vertebral trabecular bone density in children and young adults. Radiology. 2009 Jan; 250(1):222-7. PMID: 19001149; PMCID: PMC2817831.
    73. Gonzalez J, Wood JC, Dorey FJ, Wren T, Gilsanz V. Reproducibility of carotid intima-media thickness measurements in young adults. Radiology. 2008 May; 247(2):465-71. PMID: 18349312.
      View in: PubMed
    74. Wren T, Sheng M, Bowen RE, Scaduto AA, Kay RM, Otsuka NY, Hara R, Chan LS. Concurrent and discriminant validity of Spanish language instruments for measuring functional health status. J Pediatr Orthop. 2008 Mar; 28(2):199-212. PMID: 18388716.
      View in: PubMed
    75. Wren T, Bluml S, Tseng-Ong L, Gilsanz V. Three-point technique of fat quantification of muscle tissue as a marker of disease progression in Duchenne muscular dystrophy: preliminary study. AJR Am J Roentgenol. 2008 Jan; 190(1):W8-12. PMID: 18094282.
      View in: PubMed
    76. Wren T, Engsberg JR. Normalizing lower-extremity strength data for children without disability using allometric scaling. Arch Phys Med Rehabil. 2007 Nov; 88(11):1446-51. PMID: 17964886.
      View in: PubMed
    77. Wren T, Do KP, Hara R, Dorey FJ, Kay RM, Otsuka NY. Gillette Gait Index as a gait analysis summary measure: comparison with qualitative visual assessments of overall gait. J Pediatr Orthop. 2007 Oct-Nov; 27(7):765-8. PMID: 17878782.
      View in: PubMed
    78. Wren T, Do KP, Hara R, Rethlefsen SA. Use of a patella marker to improve tracking of dynamic hip rotation range of motion. Gait Posture. 2008 Apr; 27(3):530-4. PMID: 17703941.
      View in: PubMed
    79. Lee DC, Gilsanz V, Wren T. Limitations of peripheral quantitative computed tomography metaphyseal bone density measurements. J Clin Endocrinol Metab. 2007 Nov; 92(11):4248-53. PMID: 17684050.
      View in: PubMed
    80. Wren T, Mitiguy PC. A simple method to obtain consistent and clinically meaningful pelvic angles from euler angles during gait analysis. J Appl Biomech. 2007 Aug; 23(3):218-23. PMID: 18089919.
      View in: PubMed
    81. Wren T, Sheng M, Hara R, Otsuka NY, Bowen RE, Scaduto AA, Kay RM, Chan LS. Agreement among three instruments for measuring functional health status and quality of life in pediatric orthopaedics. J Pediatr Orthop. 2007 Mar; 27(2):233-40. PMID: 17314653.
      View in: PubMed
    82. Gilsanz V, Wren T. Assessment of bone acquisition in childhood and adolescence. Pediatrics. 2007 Mar; 119 Suppl 2:S145-9. PMID: 17332235.
      View in: PubMed
    83. Wren T, Kim PS, Janicka A, Sanchez M, Gilsanz V. Timing of peak bone mass: discrepancies between CT and DXA. J Clin Endocrinol Metab. 2007 Mar; 92(3):938-41. PMID: 17164299.
      View in: PubMed
    84. Wren T, Gilsanz V. Assessing bone mass in children and adolescents. Curr Osteoporos Rep. 2006 Dec; 4(4):153-8. PMID: 17112426.
      View in: PubMed
    85. Janicka A, Wren T, Sanchez MM, Dorey F, Kim PS, Mittelman SD, Gilsanz V. Fat mass is not beneficial to bone in adolescents and young adults. J Clin Endocrinol Metab. 2007 Jan; 92(1):143-7. PMID: 17047019.
      View in: PubMed
    86. Rethlefsen SA, Healy BS, Wren T, Skaggs DL, Kay RM. Causes of intoeing gait in children with cerebral palsy. J Bone Joint Surg Am. 2006 Oct; 88(10):2175-80. PMID: 17015594.
      View in: PubMed
    87. Gilsanz V, Wren T, Sanchez M, Dorey F, Judex S, Rubin C. Low-level, high-frequency mechanical signals enhance musculoskeletal development of young women with low BMD. J Bone Miner Res. 2006 Sep; 21(9):1464-74. PMID: 16939405.
      View in: PubMed
    88. Wren T, Do KP, Rethlefsen SA, Healy B. Cross-correlation as a method for comparing dynamic electromyography signals during gait. J Biomech. 2006; 39(14):2714-8. PMID: 16219314.
      View in: PubMed
    89. Wren T, Rethlefsen SA, Healy BS, Do KP, Dennis SW, Kay RM. Reliability and validity of visual assessments of gait using a modified physician rating scale for crouch and foot contact. J Pediatr Orthop. 2005 Sep-Oct; 25(5):646-50. PMID: 16199948.
      View in: PubMed
    90. Wren T, Liu X, Pitukcheewanont P, Gilsanz V. Bone densitometry in pediatric populations: discrepancies in the diagnosis of osteoporosis by DXA and CT. J Pediatr. 2005 Jun; 146(6):776-9. PMID: 15973317.
      View in: PubMed
    91. Wren T, Woolf K, Kay RM. How closely do surgeons follow gait analysis recommendations and why? J Pediatr Orthop B. 2005 May; 14(3):202-5. PMID: 15812293.
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    92. Wren T, Liu X, Pitukcheewanont P, Gilsanz V. Bone acquisition in healthy children and adolescents: comparisons of dual-energy x-ray absorptiometry and computed tomography measures. J Clin Endocrinol Metab. 2005 Apr; 90(4):1925-8. PMID: 15634720.
      View in: PubMed
    93. Wren T, Rethlefsen S, Kay RM. Prevalence of specific gait abnormalities in children with cerebral palsy: influence of cerebral palsy subtype, age, and previous surgery. J Pediatr Orthop. 2005 Jan-Feb; 25(1):79-83. PMID: 15614065.
      View in: PubMed
    94. Kay RM, Rethlefsen SA, Fern-Buneo A, Wren T, Skaggs DL. Botulinum toxin as an adjunct to serial casting treatment in children with cerebral palsy. J Bone Joint Surg Am. 2004 Nov; 86-A(11):2377-84. PMID: 15523006.
      View in: PubMed
    95. Wren T, Do KP, Kay RM. Gastrocnemius and soleus lengths in cerebral palsy equinus gait--differences between children with and without static contracture and effects of gastrocnemius recession. J Biomech. 2004 Sep; 37(9):1321-7. PMID: 15275839.
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    98. Kay RM, Rethlefsen SA, Kelly JP, Wren T. Predictive value of the Duncan-Ely test in distal rectus femoris transfer. J Pediatr Orthop. 2004 Jan-Feb; 24(1):59-62. PMID: 14676535.
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    99. Wren T. A computational model for the adaptation of muscle and tendon length to average muscle length and minimum tendon strain. J Biomech. 2003 Aug; 36(8):1117-24. PMID: 12831737.
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    100. Loboa EG, Wren T, Beaupré GS, Carter DR. Mechanobiology of soft skeletal tissue differentiation--a computational approach of a fiber-reinforced poroelastic model based on homogeneous and isotropic simplifications. Biomech Model Mechanobiol. 2003 Nov; 2(2):83-96. PMID: 14586808.
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    105. Wren T, Beaupré GS, Carter DR. Mechanobiology of tendon adaptation to compressive loading through fibrocartilaginous metaplasia. J Rehabil Res Dev. 2000 Mar-Apr; 37(2):135-43. PMID: 10850819.
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    106. Wren T, Beaupré GS, Carter DR. A model for loading-dependent growth, development, and adaptation of tendons and ligaments. J Biomech. 1998 Feb; 31(2):107-14. PMID: 9593203.
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    107. Wren T, Carter DR. A microstructural model for the tensile constitutive and failure behavior of soft skeletal connective tissues. J Biomech Eng. 1998 Feb; 120(1):55-61. PMID: 9675681.
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