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Bayesian Response Adaptive Randomization for Randomized Clinical Trials With Continuous Outcomes: The Role of Covariate Adjustment. Pharm Stat. 2024 Oct 24.
Aslanyan V, Pickering T, Nuño M, Renfro LA, Pa J, Mack WJ. PMID: 39444356.
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PubMed Mentions: Fields:
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BRAF Exon 15 Mutations in the Evaluation of Well-Differentiated Epithelial Nephroblastic Neoplasms in Children: A Report From the Children's Oncology Group Study AREN03B2. Arch Pathol Lab Med. 2024 Oct 01; 148(10):e362-e366.
Goldstein JA, Renfro LA, Jennings LJ, Mullen EA, Geller J, Vallance K, Fernandez CV, Perlman EJ. PMID: 38116848; PMCID: PMC11186972.
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PubMed Mentions: Fields:
Translation:
Humans
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Protocol-Stipulated Dose Modification to Manage Chemotherapy-Induced Peripheral Neuropathy in Children, Adolescents, and Young Adults With High-Risk Hodgkin Lymphoma. JCO Oncol Pract. 2024 Sep 20; OP2400089.
Heneghan MB, Parsons SK, Keller FG, Renfro LA, Pei Q, Rodday AM, Wu Y, Punnett A, Belsky JA, Henderson TO, Kelly KM, Castellino SM. PMID: 39303168.
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PubMed Mentions: Fields:
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Latest Developments in "Adaptive Enrichment" Clinical Trial Designs in Oncology. Ther Innov Regul Sci. 2024 Sep 13.
Tu Y, Renfro LA. PMID: 39271644.
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PubMed Mentions: Fields:
Translation:
Humans
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Long-term outcomes and patterns of relapse in patients with bilateral Wilms tumor or bilaterally predisposed unilateral Wilms tumor, a report from the COG AREN0534 study. Int J Cancer. 2024 Jul 08.
Murphy AJ, Brzezinski J, Renfro LA, Tornwall B, Malek MM, Benedetti DJ, Cost NG, Smith EA, Aldrink J, Romao RLP, Dome JS, Davidoff AM, Treece AL, Parsons LN, Mullen EA, Shamberger RC, Paulino AC, Lo AC, Geller JI, Ehrlich PF. PMID: 38973574.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Biomarker-driven basket trial designs: origins and new methodological developments. J Biopharm Stat. 2024 Jun 04; 1-13.
Tu Y, Renfro LA. PMID: 38832723.
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PubMed Mentions: Fields:
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Bilateral Wilms tumor with anaplasia: A report from the Children's Oncology Group Study AREN0534. Pediatr Blood Cancer. 2024 Jul; 71(7):e30981.
Romao RLP, Aldrink JH, Renfro LA, Mullen EA, Murphy AJ, Brzezinski J, Malek MM, Benedetti DJ, Cost NG, Smith E, Dome JS, Davidoff AM, Treece A, Parsons LN, Fernandez CV, Tornwall B, Shamberger RC, Paulino A, Kalapurakal JA, Geller JI, Ehrlich PF. PMID: 38637871; PMCID: PMC11116047.
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Translation:
Humans
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Race and Ethnic Group Enrollment and Outcomes for Wilms Tumor: Analysis of the Current Era Children's Oncology Group Study, AREN03B2. J Am Coll Surg. 2024 Apr 01; 238(4):733-749.
Lovvorn HN, Renfro LA, Benedetti DJ, Kotagal M, Phelps HM, Ehrlich PF, Lo AC, Sandberg JK, Treece AL, Gow KW, Glick RD, Davidoff AM, Cost NG, Dix DB, Fernandez CV, Dome JS, Geller JI, Mullen EA. PMID: 38251681; PMCID: PMC11138877.
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Translation:
Humans
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Considerations on Design and Analysis of External Control in Pediatric Oncology. Med Res Arch. 2024 Jan; 12(1).
Ye J, Pan H, Reaman G, Roychoudhury S, Lu C, Renfro LA, Ji Y, Liu R, Yuan Y, Zhang W. PMID: 39026931; PMCID: PMC11257159.
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PubMed Mentions:
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Treatment and outcomes of clear cell sarcoma of the kidney: A report from the Children's Oncology Group studies AREN0321 and AREN03B2. Cancer. 2024 Jul 01; 130(13):2361-2371.
Benedetti DJ, Renfro LA, Tfirn I, Daw NC, Kalapurakal JA, Ehrlich PF, Khanna G, Perlman E, Warwick A, Gow KW, Paulino AC, Seibel NL, Grundy P, Fernandez CV, Geller JI, Mullen EA, Dome JS. PMID: 38396300; PMCID: PMC11162327.
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Translation:
HumansCTClinical Trials
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Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children's Oncology Group AREN18B5-Q. Nat Commun. 2023 Dec 18; 14(1):8006.
Murphy AJ, Cheng C, Williams J, Shaw TI, Pinto EM, Dieseldorff-Jones K, Brzezinski J, Renfro LA, Tornwall B, Huff V, Hong AL, Mullen EA, Crompton B, Dome JS, Fernandez CV, Geller JI, Ehrlich PF, Mulder H, Oak N, Maciezsek J, Jablonowski CM, Fleming AM, Pichavaram P, Morton CL, Easton J, Nichols KE, Clay MR, Santiago T, Zhang J, Yang J, Zambetti GP, Wang Z, Davidoff AM, Chen X. PMID: 38110397; PMCID: PMC10728430.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Treatment of children with favorable histology Wilms tumor with extrapulmonary metastases: A report from the COG studies AREN0533 and AREN03B2 and NWTSG study NWTS-5. Cancer. 2024 03 15; 130(6):947-961.
Benedetti DJ, Varela CR, Renfro LA, Tornwall B, Dix DB, Ehrlich PF, Glick RD, Kalapurakal J, Perlman E, Gratias E, Seibel NL, Geller JI, Khanna G, Malogolowkin M, Grundy P, Fernandez CV, Dome JS, Mullen EA. PMID: 37933882; PMCID: PMC10922062.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Prognostic impact of lymph node involvement and loss of heterozygosity of 1p or 16q in stage III favorable histology Wilms tumor: A report from Children's Oncology Group Studies AREN03B2 and AREN0532. Cancer. 2024 03 01; 130(5):792-802.
Evageliou N, Renfro LA, Geller J, Perlman E, Kalapurakal J, Paulino A, Dix D, Eklund MJ, Murphy AJ, Romao RLP, Ehrlich PF, Varela CR, Vallance K, Fernandez CV, Dome JS, Mullen EA. PMID: 37902955; PMCID: PMC10993001.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Children's Oncology Group's 2023 blueprint for research: Renal tumors. Pediatr Blood Cancer. 2023 09; 70 Suppl 6:e30586.
Geller JI, Hong AL, Vallance KL, Evageliou N, Aldrink JH, Cost NG, Treece AL, Renfro LA, Mullen EA, COG Renal Tumor Committee. PMID: 37477907; PMCID: PMC10529605.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Severe Hepatopathy in National Wilms Tumor Studies 3-5: Prevalence, Clinical Features, and Outcomes After Reintroduction of Chemotherapy. J Clin Oncol. 2023 09 10; 41(26):4247-4256.
Oosterom N, Gooskens SLM, Renfro LA, Perlman EJ, van den Heuvel-Eibrink MM, Hamilton TE, Green DM, Grundy PE, Daw NC, Geller JI, Dome JS, Fernandez CV, Mullen EA. PMID: 37343199; PMCID: PMC10852371.
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Translation:
Humans
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The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study. Res Sq. 2023 Mar 16.
Murphy AJ, Cheng C, Williams J, Shaw TI, Pinto EM, Dieseldorff-Jones K, Brzezinski J, Renfro LA, Tornwall B, Huff V, Hong AL, Mullen EA, Crompton B, Dome JS, Fernandez CV, Geller JI, Ehrlich PF, Mulder H, Oak N, Maciezsek J, Jablonowski C, Fleming AM, Pichavaram P, Morton CL, Easton J, Nichols KE, Clay MR, Santiago T, Zhang J, Yang J, Zambetti GP, Wang Z, Davidoff AM, Chen X. PMID: 36993649; PMCID: PMC10055651.
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Genetic changes associated with relapse in favorable histology Wilms tumor: A Children's Oncology Group AREN03B2 study. Cell Rep Med. 2022 06 21; 3(6):100644.
Gadd S, Huff V, Skol AD, Renfro LA, Fernandez CV, Mullen EA, Jones CD, Hoadley KA, Yap KL, Ramirez NC, Aris S, Phung QH, Perlman EJ. PMID: 35617957; PMCID: PMC9244995.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533. J Clin Oncol. 2022 09 10; 40(26):3047-3056.
Madanat-Harjuoja LM, Renfro LA, Klega K, Tornwall B, Thorner AR, Nag A, Dix D, Dome JS, Diller LR, Fernandez CV, Mullen EA, Crompton BD. PMID: 35580298; PMCID: PMC9462535.
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PubMed Mentions:
16 Fields:
Translation:
HumansCTClinical Trials
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Authors' Reply to the Letter to the Editor by Daniel M. Green. J Natl Compr Canc Netw. 2022 03; 20(3):xlvii-xlviii.
Dome JS, Mullen EA, Dix DB, Gratias EJ, Ehrlich PF, Daw NC, Geller JI, Chintagumpala M, Khanna G, Kalapurakal JA, Renfro L, Perlman EJ, Grundy PE, Fernandez CV. PMID: 35276672.
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PubMed Mentions: Fields:
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Bayesian adaptive trial design for a continuous biomarker with possibly nonlinear or nonmonotone prognostic or predictive effects. Biometrics. 2022 12; 78(4):1441-1453.
Liu Y, Kairalla JA, Renfro LA. PMID: 34415052; PMCID: PMC8858338.
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Translation:
Humans
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Impact of the First Generation of Children's Oncology Group Clinical Trials on Clinical Practice for Wilms Tumor. J Natl Compr Canc Netw. 2021 08 01; 19(8):978-985.
Dome JS, Mullen EA, Dix DB, Gratias EJ, Ehrlich PF, Daw NC, Geller JI, Chintagumpala M, Khanna G, Kalapurakal JA, Renfro LA, Perlman EJ, Grundy PE, Fernandez CV. PMID: 34416705; PMCID: PMC8805512.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Point and interval estimation in two-stage adaptive designs with time to event data and biomarker-driven subpopulation selection. Stat Med. 2020 08 30; 39(19):2568-2586.
Kimani PK, Todd S, Renfro LA, Glimm E, Khan JN, Kairalla JA, Stallard N. PMID: 32363603; PMCID: PMC7785132.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Reply to D.M. Green. J Clin Oncol. 2020 03 01; 38(7):773-774.
Dix DB, Fernandez CV, Chi YY, Renfro LA, Md JSD. PMID: 31951494; PMCID: PMC7048164.
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Translation:
Humans
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Trial Design Challenges and Approaches for Precision Oncology in Rare Tumors: Experiences of the Children's Oncology Group. JCO Precis Oncol. 2019; 3.
Renfro LA, Ji L, Piao J, Onar-Thomas A, Kairalla JA, Alonzo TA. PMID: 32923863; PMCID: PMC7446492.
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PubMed Mentions:
15 Fields:
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Influence of genetic variation in the vitamin D pathway on plasma 25-hydroxyvitamin D3 levels and survival among patients with metastatic colorectal cancer. Cancer Causes Control. 2019 Jul; 30(7):757-765.
Yuan C, Renfro L, Ambadwar PB, Ou FS, McLeod HL, Innocenti F, Meyerhardt JA, Wolpin BM, Goldberg RM, Grothey A, Fuchs CS, Ng K. PMID: 31104167; PMCID: PMC6639016.
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PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
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On the need to adjust for multiplicity in confirmatory clinical trials with master protocols. Ann Oncol. 2019 04 01; 30(4):506-509.
Stallard N, Todd S, Parashar D, Kimani PK, Renfro LA. PMID: 30715156; PMCID: PMC6503623.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database. Eur J Cancer. 2018 11; 103:205-213.
Salem ME, Yin J, Weinberg BA, Renfro LA, Pederson LD, Maughan TS, Adams RA, Van Cutsem E, Falcone A, Tebbutt NC, Seymour MT, Díaz-Rubio E, Aranda E, Bokemeyer C, Heinemann V, Wasan H, de Gramont A, Grothey A, Shi Q, Sargent DJ, Marshall JL. PMID: 30268921.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. J Natl Cancer Inst. 2018 06 01; 110(6):638-648.
Sjoquist KM, Renfro LA, Simes RJ, Tebbutt NC, Clarke S, Seymour MT, Adams R, Maughan TS, Saltz L, Goldberg RM, Schmoll HJ, Van Cutsem E, Douillard JY, Hoff PM, Hecht JR, Tournigand C, Punt CJA, Koopman M, Hurwitz H, Heinemann V, Falcone A, Porschen R, Fuchs C, Diaz-Rubio E, Aranda E, Bokemeyer C, Souglakos I, Kabbinavar FF, Chibaudel B, Meyers JP, Sargent DJ, de Gramont A, Zalcberg JR, Fondation Aide et Recherche en Cancerologie Digestive Group (ARCAD). PMID: 29267900; PMCID: PMC6005015.
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PubMed Mentions:
57 Fields:
Translation:
HumansCTClinical Trials
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Point estimation following two-stage adaptive threshold enrichment clinical trials. Stat Med. 2018 09 30; 37(22):3179-3196.
Kimani PK, Todd S, Renfro LA, Stallard N. PMID: 29855066; PMCID: PMC6175016.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Duration of Adjuvant Chemotherapy for Stage III Colon Cancer. N Engl J Med. 2018 Mar 29; 378(13):1177-1188.
Grothey A, Sobrero AF, Shields AF, Yoshino T, Paul J, Taieb J, Souglakos J, Shi Q, Kerr R, Labianca R, Meyerhardt JA, Vernerey D, Yamanaka T, Boukovinas I, Meyers JP, Renfro LA, Niedzwiecki D, Watanabe T, Torri V, Saunders M, Sargent DJ, Andre T, Iveson T. PMID: 29590544; PMCID: PMC6426127.
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PubMed Mentions:
372 Fields:
Translation:
Humans
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A Randomized, Double-Blind, Placebo-Controlled Phase II Study of the Efficacy and Safety of Monotherapy Ontuxizumab (MORAb-004) Plus Best Supportive Care in Patients with Chemorefractory Metastatic Colorectal Cancer. Clin Cancer Res. 2018 01 15; 24(2):316-325.
Grothey A, Strosberg JR, Renfro LA, Hurwitz HI, Marshall JL, Safran H, Guarino MJ, Kim GP, Hecht JR, Weil SC, Heyburn J, Wang W, Schweizer C, O'Shannessy DJ, Diaz LA. PMID: 29084918.
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PubMed Mentions:
19 Fields:
Translation:
HumansCTClinical Trials
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Definitions and statistical properties of master protocols for personalized medicine in oncology. J Biopharm Stat. 2018; 28(2):217-228.
Renfro LA, Mandrekar SJ. PMID: 28877008.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer. J Clin Oncol. 2017 Aug 10; 35(23):2624-2630.
Jones JC, Renfro LA, Al-Shamsi HO, Schrock AB, Rankin A, Zhang BY, Kasi PM, Voss JS, Leal AD, Sun J, Ross J, Ali SM, Hubbard JM, Kipp BR, McWilliams RR, Kopetz S, Wolff RA, Grothey A. PMID: 28486044; PMCID: PMC5549454.
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PubMed Mentions:
169 Fields:
Translation:
Humans
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Anorectal Function and Quality of Life in Patients With Early Stage Rectal Cancer Treated With Chemoradiation and Local Excision. Dis Colon Rectum. 2017 May; 60(5):459-468.
Lynn PB, Renfro LA, Carrero XW, Shi Q, Strombom PL, Chow O, Garcia-Aguilar J. PMID: 28383445; PMCID: PMC5384260.
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PubMed Mentions:
8 Fields:
Translation:
HumansCTClinical Trials
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Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancérologie Digestive Database. J Clin Oncol. 2017 Jun 10; 35(17):1929-1937.
Renfro LA, Goldberg RM, Grothey A, Sobrero A, Adams R, Seymour MT, Heinemann V, Schmoll HJ, Douillard JY, Hurwitz H, Fuchs CS, Diaz-Rubio E, Porschen R, Tournigand C, Chibaudel B, Hoff PM, Kabbinavar FF, Falcone A, Tebbutt NC, Punt CJA, Hecht JR, Souglakos J, Bokemeyer C, Van Cutsem E, Saltz L, de Gramont A, Sargent DJ, ARCAD Clinical Trials Program. PMID: 28414610; PMCID: PMC5466009.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Statistical controversies in clinical research: basket trials, umbrella trials, and other master protocols: a review and examples. Ann Oncol. 2017 01 01; 28(1):34-43.
Renfro LA, Sargent DJ. PMID: 28177494; PMCID: PMC5834138.
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PubMed Mentions:
89 Fields:
Translation:
Humans
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Findings from the Adjuvant Colon Cancer End Points (ACCENT) Collaborative Group: the power of pooled individual patient data from multiple clinical trials. Chin Clin Oncol. 2016 Dec; 5(6):80.
Renfro LA, Sargent DJ. PMID: 28061544.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Surrogate End Points in Soft Tissue Sarcoma: Methodologic Challenges. J Clin Oncol. 2016 11 10; 34(32):3949-3950.
Renfro LA, Shi Q, Sargent DJ. PMID: 27551133.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Prospective Evaluation of a 12-Gene Assay on Patient Treatment Decisions and Physician Confidence in Mismatch Repair Proficient Stage IIA Colon Cancer. Clin Colorectal Cancer. 2017 03; 16(1):23-30.
Renfro LA, Zhang N, Lopatin M, Chao C, Alberts SR. PMID: 27600983; PMCID: PMC5299063.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Validity of Adjuvant! Online in older patients with stage III colon cancer based on 2967 patients from the ACCENT database. J Geriatr Oncol. 2016 11; 7(6):422-429.
Papamichael D, Renfro LA, Matthaiou C, Yothers G, Saltz L, Guthrie KA, Van Cutsem E, Schmoll HJ, Labianca R, André T, O'Connell M, Alberts SR, Haller DG, Kountourakis P, Sargent DJ, Adjuvant Colon Cancer Endpoints (ACCENT) Group. PMID: 27468630; PMCID: PMC5159186.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Precision oncology: A new era of cancer clinical trials. Cancer Lett. 2017 02 28; 387:121-126.
Renfro LA, An MW, Mandrekar SJ. PMID: 26987624; PMCID: PMC5023449.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Determinants of Early Mortality Among 37,568 Patients With Colon Cancer Who Participated in 25 Clinical Trials From the Adjuvant Colon Cancer Endpoints Database. J Clin Oncol. 2016 Apr 10; 34(11):1182-9.
Cheung WY, Renfro LA, Kerr D, de Gramont A, Saltz LB, Grothey A, Alberts SR, Andre T, Guthrie KA, Labianca R, Francini G, Seitz JF, O'Callaghan C, Twelves C, Van Cutsem E, Haller DG, Yothers G, Sargent DJ. PMID: 26858337; PMCID: PMC4933130.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Impact of Patient Factors on Recurrence Risk and Time Dependency of Oxaliplatin Benefit in Patients With Colon Cancer: Analysis From Modern-Era Adjuvant Studies in the Adjuvant Colon Cancer End Points (ACCENT) Database. J Clin Oncol. 2016 Mar 10; 34(8):843-53.
Shah MA, Renfro LA, Allegra CJ, André T, de Gramont A, Schmoll HJ, Haller DG, Alberts SR, Yothers G, Sargent DJ. PMID: 26811529; PMCID: PMC4872008.
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PubMed Mentions:
65 Fields:
Translation:
Humans
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Clinical trial designs incorporating predictive biomarkers. Cancer Treat Rev. 2016 Feb; 43:74-82.
Renfro LA, Mallick H, An MW, Sargent DJ, Mandrekar SJ. PMID: 26827695; PMCID: PMC4737867.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database. J Clin Oncol. 2016 Jan 10; 34(2):144-50.
Renfro LA, Loupakis F, Adams RA, Seymour MT, Heinemann V, Schmoll HJ, Douillard JY, Hurwitz H, Fuchs CS, Diaz-Rubio E, Porschen R, Tournigand C, Chibaudel B, Falcone A, Tebbutt NC, Punt CJ, Hecht JR, Bokemeyer C, Van Cutsem E, Goldberg RM, Saltz LB, de Gramont A, Sargent DJ, Lenz HJ. PMID: 26503203; PMCID: PMC5070548.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Organ preservation for clinical T2N0 distal rectal cancer using neoadjuvant chemoradiotherapy and local excision (ACOSOG Z6041): results of an open-label, single-arm, multi-institutional, phase 2 trial. Lancet Oncol. 2015 Nov; 16(15):1537-1546.
Garcia-Aguilar J, Renfro LA, Chow OS, Shi Q, Carrero XW, Lynn PB, Thomas CR, Chan E, Cataldo PA, Marcet JE, Medich DS, Johnson CS, Oommen SC, Wolff BG, Pigazzi A, McNevin SM, Pons RK, Bleday R. PMID: 26474521; PMCID: PMC4984260.
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PubMed Mentions:
131 Fields:
Translation:
HumansCTClinical Trials
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Multitrial Evaluation of Progression-Free Survival as a Surrogate End Point for Overall Survival in First-Line Extensive-Stage Small-Cell Lung Cancer. J Thorac Oncol. 2015 Jul; 10(7):1099-106.
Foster NR, Renfro LA, Schild SE, Redman MW, Wang XF, Dahlberg SE, Ding K, Bradbury PA, Ramalingam SS, Gandara DR, Shibata T, Saijo N, Vokes EE, Adjei AA, Mandrekar SJ. PMID: 26134227; PMCID: PMC4493926.
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PubMed Mentions:
27 Fields:
Translation:
HumansCTClinical Trials
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Survival following early-stage colon cancer: an ACCENT-based comparison of patients versus a matched international general population†. Ann Oncol. 2015 May; 26(5):950-958.
Renfro LA, Grothey A, Kerr D, Haller DG, André T, Van Cutsem E, Saltz L, Labianca R, Loprinzi CL, Alberts SR, Schmoll H, Twelves C, Yothers G, Sargent DJ, Adjuvant Colon Cancer Endpoints (ACCENT) Group. PMID: 25697217; PMCID: PMC4405281.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Impact of Copula Directional Specification on Multi-Trial Evaluation of Surrogate End Points. J Biopharm Stat. 2015; 25(4):857-77.
Renfro LA, Shang H, Sargent DJ. PMID: 24905465; PMCID: PMC4270950.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Projecting Event-Based Analysis Dates in Clinical Trials: An Illustration Based on the International Duration Evaluation of Adjuvant Chemotherapy (IDEA) Collaboration. Projecting analysis dates for the IDEA collaboration. Forum Clin Oncol. 2014 Dec; 5(2):1-7.
Renfro LA, Grothey AM, Paul J, Floriani I, Bonnetain F, Niedzwiecki D, Yamanaka T, Souglakos I, Yothers G, Sargent DJ. PMID: 26989447; PMCID: PMC4792190.
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PubMed Mentions:
1
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Comparative economics of a 12-gene assay for predicting risk of recurrence in stage II colon cancer. Pharmacoeconomics. 2014 Dec; 32(12):1231-43.
Alberts SR, Yu TM, Behrens RJ, Renfro LA, Srivastava G, Soori GS, Dakhil SR, Mowat RB, Kuebler JP, Kim GP, Mazurczak MA, Hornberger J. PMID: 25154747; PMCID: PMC4244576.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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ACCENT-based web calculators to predict recurrence and overall survival in stage III colon cancer. J Natl Cancer Inst. 2014 Dec; 106(12).
Renfro LA, Grothey A, Xue Y, Saltz LB, André T, Twelves C, Labianca R, Allegra CJ, Alberts SR, Loprinzi CL, Yothers G, Sargent DJ, Adjuvant Colon Cancer Endpoints (ACCENT) Group. PMID: 25359867; PMCID: PMC4334801.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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MRE11-deficiency associated with improved long-term disease free survival and overall survival in a subset of stage III colon cancer patients in randomized CALGB 89803 trial. PLoS One. 2014; 9(10):e108483.
Pavelitz T, Renfro L, Foster NR, Caracol A, Welsch P, Lao VV, Grady WB, Niedzwiecki D, Saltz LB, Bertagnolli MM, Goldberg RM, Rabinovitch PS, Emond M, Monnat RJ, Maizels N. PMID: 25310185; PMCID: PMC4195600.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Center-Within-Trial Versus Trial-Level Evaluation of Surrogate Endpoints. Comput Stat Data Anal. 2014 Oct 01; 78:1-20.
Renfro LA, Shi Q, Xue Y, Li J, Shang H, Sargent DJ. PMID: 25061255; PMCID: PMC4104720.
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PubMed Mentions:
3
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Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD Clinical Trials Program. J Clin Oncol. 2014 Sep 20; 32(27):2975-84.
Lieu CH, Renfro LA, de Gramont A, Meyers JP, Maughan TS, Seymour MT, Saltz L, Goldberg RM, Sargent DJ, Eckhardt SG, Eng C, Aide et Recherche en Cancérologie Digestive Foundation. PMID: 25002720; PMCID: PMC4809210.
View in:
PubMed Mentions:
71 Fields:
Translation:
Humans
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CpG island methylator phenotype is associated with response to adjuvant irinotecan-based therapy for stage III colon cancer. Gastroenterology. 2014 Sep; 147(3):637-45.
Shiovitz S, Bertagnolli MM, Renfro LA, Nam E, Foster NR, Dzieciatkowski S, Luo Y, Lao VV, Monnat RJ, Emond MJ, Maizels N, Niedzwiecki D, Goldberg RM, Saltz LB, Venook A, Warren RS, Grady WM, Alliance for Clinical Trials in Oncology. PMID: 24859205; PMCID: PMC4143495.
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PubMed Mentions:
70 Fields:
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HumansCellsCTClinical Trials
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Genetic markers of treatment response to tumour necrosis factor-α inhibitors in the treatment of psoriasis. Clin Exp Dermatol. 2014 Jun; 39(4):519-24.
Ryan C, Kelleher J, Fagan MF, Rogers S, Collins P, Barker JN, Allen M, Hagan R, Renfro L, Kirby B. PMID: 24758522.
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13 Fields:
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Humans
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Germline variation in colorectal risk Loci does not influence treatment effect or survival in metastatic colorectal cancer. PLoS One. 2014; 9(4):e94727.
Sanoff HK, Renfro LA, Poonnen P, Ambadwar P, Sargent DJ, Goldberg RM, McLeod H. PMID: 24727911; PMCID: PMC3984266.
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PubMed Mentions:
2 Fields:
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Humans
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Prospective multicenter study of the impact of oncotype DX colon cancer assay results on treatment recommendations in stage II colon cancer patients. Oncologist. 2014 May; 19(5):492-7.
Srivastava G, Renfro LA, Behrens RJ, Lopatin M, Chao C, Soori GS, Dakhil SR, Mowat RB, Kuebler JP, Kim G, Mazurczak M, Lee M, Alberts SR. PMID: 24710310; PMCID: PMC4012966.
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24 Fields:
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Humans
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Adaptive randomized phase II design for biomarker threshold selection and independent evaluation. Chin Clin Oncol. 2014 Mar 01; 3(1).
Renfro LA, Coughlin CM, Grothey AM, Sargent DJ. PMID: 25485277; PMCID: PMC4255950.
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10 Fields:
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Adaptive randomized phase II design for biomarker threshold selection and independent evaluation. Chin Clin Oncol. 2014 Mar; 3(1):3.
Renfro LA, Coughlin CM, Grothey AM, Sargent DJ. PMID: 25842081.
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Mining the ACCENT database: a review and update. Chin Clin Oncol. 2013 Jun; 2(2):18.
Renfro LA, Shi Q, Sargent DJ. PMID: 25841498; PMCID: PMC4407359.
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5 Fields:
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Chronic consequences of acute injuries: worse survival after discharge. J Trauma Acute Care Surg. 2012 Sep; 73(3):699-703.
Shafi S, Renfro LA, Barnes S, Rayan N, Gentilello LM, Fleming N, Ballard D. PMID: 22710768.
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7 Fields:
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Humans
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Bayesian adjusted R2 for the meta-analytic evaluation of surrogate time-to-event endpoints in clinical trials. Stat Med. 2012 Apr 13; 31(8):743-61.
Renfro LA, Shi Q, Sargent DJ, Carlin BP. PMID: 22161275.
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11 Fields:
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Humans
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Bayesian adaptive trial design for a newly validated surrogate endpoint. Biometrics. 2012 Mar; 68(1):258-67.
Renfro LA, Carlin BP, Sargent DJ. PMID: 21838811; PMCID: PMC3218207.
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3 Fields:
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Clinical and genetic predictors of response to narrowband ultraviolet B for the treatment of chronic plaque psoriasis. Br J Dermatol. 2010 Nov; 163(5):1056-63.
Ryan C, Renfro L, Collins P, Kirby B, Rogers S. PMID: 20716226.
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9 Fields:
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Humans
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Neutrophilic sebaceous adenitis. Arch Dermatol. 1993 Jul; 129(7):910-1.
Renfro L, Kopf AW, Gutterman A, Gottlieb GJ, Jacobson M. PMID: 8323320.
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1 Fields:
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HumansCells
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Persistent plaque on the shoulder of a Chinese woman. BCG granuloma. Arch Dermatol. 1993 Feb; 129(2):233, 236.
Renfro L, Miller D, Raszi L, Kamino H. PMID: 8434985.
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Anatomical differences of port-wine stains in response to treatment with the pulsed dye laser. Arch Dermatol. 1993 Feb; 129(2):182-8.
Renfro L, Geronemus RG. PMID: 8434975.
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29 Fields:
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Humans
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Painful nodules in a young female. Antiphospholipid syndrome. Arch Dermatol. 1992 Jun; 128(6):847-8, 850-1.
Renfro L, Franks AG, Grodberg M, Kamino H. PMID: 1599278.
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PubMed Mentions:
2 Fields:
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Humans
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Lack of efficacy of the Q-switched ruby laser in the treatment of vitiligo. Arch Dermatol. 1992 Feb; 128(2):277-8.
Renfro L, Geronemus RG. PMID: 1739317.
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HumansCTClinical Trials
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Ulcerative lichen planus-like dermatitis associated with hydroxyurea. J Am Acad Dermatol. 1991 Jan; 24(1):143-5.
Renfro L, Kamino H, Raphael B, Moy J, Sanchez M. PMID: 1825667.
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PubMed Mentions:
1 Fields:
Translation:
Humans