Enrique Cadenas, MD, PhD

Title(s)Professor
SchoolUSC School of Pharmacy
AddressPSC 612
Health Sciences Campus
Los Angeles CA 90089-9121
Phone+1 323 442 1418
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    Dr. Cadenas received his M.D. and Ph.D. degrees from the University of Buenos Aires. He served as a research fellow at the Universities of Dundee (Scotland), Pennsylvania (USA) and Dusseldorf (Germany). Prior to coming to USC in 1989, Dr. Cadenas was an associate professor of pathology at the University of Linkoping (Sweden). Currently, he is a professor of molecular pharmacology and toxicology (USC School of Pharmacy) and professor of biochemistry (USC Keck School of Medicine).

    Research Interests:

    The anomalous regulation of apoptosis has been recognized as a pathological process that occurs in a variety of conditions comprising neurodegenerative diseases, autoimmune disorders, and various cancers. We are interested in elucidating the molecular mechanisms underlying cell signaling pathways inherent in mitochondrion-dependent apoptosis and with implications for neurodegenerative- and age-related disorders.

    Ongoing research projects within these long-term goals are: (a) the study of the potential biological role of mitochondria as an important cellular target of pro-apoptotic JNK signalling involving modulation of Bcl-2 family members; (b) the regulation of mitochondrial functions by nitric oxide and the mitochondrial nitric oxide synthase and how they impinge on the cellular redox state; (c) analysis of the mitochondrial proteome for post-translational modifications caused by JNK activity and exposure to oxidative and nitrosative stress; (d) the analysis of the mechanism of actions of neuroprotective agents in terms of preserving mitochondrion functional integrity through activation of ligand-independent signaling pathways and universal transcription factors.

    Collapse Research 
    Collapse Research Activities and Funding
    2013 Oxidative Stress and Disease Gordon Research Conference & Seminar
    NIH R13AG044908Mar 15, 2013 - Feb 28, 2014
    Role: Principal Investigator
    XIIIth Biennial Meeting of the Society for Free Radical Research International
    NIH R13CA124282Aug 1, 2006 - Jul 31, 2007
    Role: Principal Investigator
    Mitochondrial oxidative damage in dopaminergic cells
    NIH R01ES011342Jul 11, 2001 - Jun 30, 2007
    Role: Principal Investigator
    Oxidative Stress, Mitochondrial Dysfunction and Aging
    NIH R01AG016718Apr 1, 1999 - May 31, 2011
    Role: Principal Investigator
    BIOCHEMICAL TOXICOLOGY OF MYOGLOBIN OXIDATION STATES
    NIH R01HL053467Jul 1, 1995 - Jun 30, 1999
    Role: Principal Investigator
    MODULATION OF QUINONE TOXICITY BY TWO-ELECTRON TRANSFERS
    NIH R01ES005423Jul 1, 1990 - Jun 30, 1996
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dihydromyricetin supplementation improves ethanol-induced lipid accumulation and inflammation. Front Nutr. 2023; 10:1201007. Janilkarn-Urena I, Idrissova A, Zhang M, VanDreal M, Sanghavi N, Skinner SG, Cheng S, Zhang Z, Watanabe J, Asatryan L, Cadenas E, Davies DL. PMID: 37680900; PMCID: PMC10481966.
      View in: PubMed   Mentions:
    2. In Memoriam: Pierre Cillard (1942-2023). Free Radic Biol Med. 2023 Aug 10; 206:191-192. Oteiza PI, Fraga CG, Cadenas E, Davies JMS, Davies KJA. PMID: 37572453.
      View in: PubMed   Mentions:    Fields:    
    3. Lester Packer: On His Life and His Legacy. Antioxid Redox Signal. 2023 04; 38(10-12):768-774. Cadenas E, Sies H. PMID: 36006367.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    4. Using the Cyclotide Scaffold for Targeting Biomolecular Interactions in Drug Development. Molecules. 2022 Sep 29; 27(19). Jacob B, Vogelaar A, Cadenas E, Camarero JA. PMID: 36234971; PMCID: PMC9570680.
      View in: PubMed   Mentions: 6     Fields:    
    5. Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β. Front Physiol. 2022; 13:930402. Garcia J, Chang R, Steinberg RA, Arce A, Yang J, Van Der Eb P, Abdullah T, Chandrashekar DV, Eck SM, Meza P, Liu ZX, Cadenas E, Cribbs DH, Kaplowitz N, Sumbria RK, Han D. PMID: 36187787; PMCID: PMC9520570.
      View in: PubMed   Mentions: 7  
    6. Reprint of: Production of Superoxide Radicals and Hydrogen Peroxide by NADH- Ubiquinone Reductase and Ubiquinol-Cytochrome c Reductase from Beef-Heart Mitochondria. Arch Biochem Biophys. 2022 09 15; 726:109231. Cadenas E, Boveris A, Ian Ragan C, O M Stoppani A. PMID: 35660298.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. On 'Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria' by Enrique Cadenas, Alberto Boveris, C. Ian Ragan and Andres O.M.Stoppani. Arch Biochem Biophys. 2022 09 15; 726:109214. Cadenas E. PMID: 35483432.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    8. Redox Pioneer: Professor Valerian Kagan. Antioxid Redox Signal. 2022 05; 36(13-15):813-823. Bayir H, Maguire JJ, Cadenas E. PMID: 35072541; PMCID: PMC9127833.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Commentary on "Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria". Arch Biochem Biophys. 2022 Mar 29; 721:109197. Cadenas E. PMID: 35364049.
      View in: PubMed   Mentions:    Fields:    
    10. Inhibition of Estrogen-Related Receptor α Blocks Liver Steatosis and Steatohepatitis and Attenuates Triglyceride Biosynthesis. Am J Pathol. 2021 07; 191(7):1240-1254. Chen CY, Li Y, Zeng N, He L, Zhang X, Tu T, Tang Q, Alba M, Mir S, Stiles EX, Hong H, Cadenas E, Stolz AA, Li G, Stiles BL. PMID: 33894178; PMCID: PMC8261472.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    11. Methionine restriction alleviates age-associated cognitive decline via fibroblast growth factor 21. Redox Biol. 2021 05; 41:101940. Ren B, Wang L, Shi L, Jin X, Liu Y, Liu RH, Yin F, Cadenas E, Dai X, Liu Z, Liu X. PMID: 33765615; PMCID: PMC8022247.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    12. High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis. Cell Metab. 2021 05 04; 33(5):923-938.e6. Liu X, Li X, Xia B, Jin X, Zou Q, Zeng Z, Zhao W, Yan S, Li L, Yuan S, Zhao S, Dai X, Yin F, Cadenas E, Liu RH, Zhao B, Hou M, Liu Z, Liu X. PMID: 33651981.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansAnimalsCells
    13. The bioactivity of neuronal-derived nitric oxide in aging and neurodegeneration: Switching signaling to degeneration. Free Radic Biol Med. 2021 01; 162:500-513. Ledo A, Lourenço CF, Cadenas E, Barbosa RM, Laranjinha J. PMID: 33186742.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    14. Dihydromyricetin improves mitochondrial outcomes in the liver of alcohol-fed mice via the AMPK/Sirt-1/PGC-1α signaling axis. Alcohol. 2021 03; 91:1-9. Silva J, Spatz MH, Folk C, Chang A, Cadenas E, Liang J, Davies DL. PMID: 33080338; PMCID: PMC7902334.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    15. Mitochondria as Target for Tumor Management of Hemangioendothelioma. Antioxid Redox Signal. 2021 01 10; 34(2):137-153. Gordillo GM, Biswas A, Singh K, Sen A, Guda PR, Miller C, Pan X, Khanna S, Cadenas E, Sen CK. PMID: 32597200; PMCID: PMC7757590.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    16. Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment. Nat Commun. 2020 02 18; 11(1):855. Liu Z, Dai X, Zhang H, Shi R, Hui Y, Jin X, Zhang W, Wang L, Wang Q, Wang D, Wang J, Tan X, Ren B, Liu X, Zhao T, Wang J, Pan J, Yuan T, Chu C, Lan L, Yin F, Cadenas E, Shi L, Zhao S, Liu X. PMID: 32071312; PMCID: PMC7029019.
      View in: PubMed   Mentions: 163     Fields:    Translation:AnimalsCells
    17. Treadmill exercise rescues mitochondrial function and motor behavior in the CAG140 knock-in mouse model of Huntington's disease. Chem Biol Interact. 2020 Jan 05; 315:108907. Caldwell CC, Petzinger GM, Jakowec MW, Cadenas E. PMID: 31778667.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    18. Brain metabolic and functional alterations in a liver-specific PTEN knockout mouse model. PLoS One. 2018; 13(9):e0204043. Patil I, Sancheti H, Stiles BL, Cadenas E. PMID: 30235271; PMCID: PMC6147462.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    19. The Oxygen Paradox, the French Paradox, and age-related diseases. Geroscience. 2017 12; 39(5-6):499-550. Davies JMS, Cillard J, Friguet B, Cadenas E, Cadet J, Cayce R, Fishmann A, Liao D, Bulteau AL, Derbré F, Rébillard A, Burstein S, Hirsch E, Kloner RA, Jakowec M, Petzinger G, Sauce D, Sennlaub F, Limon I, Ursini F, Maiorino M, Economides C, Pike CJ, Cohen P, Salvayre AN, Halliday MR, Lundquist AJ, Jakowec NA, Mechta-Grigoriou F, Mericskay M, Mariani J, Li Z, Huang D, Grant E, Forman HJ, Finch CE, Sun PY, Pomatto LCD, Agbulut O, Warburton D, Neri C, Rouis M, Cillard P, Capeau J, Rosenbaum J, Davies KJA. PMID: 29270905; PMCID: PMC5745211.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    20. Effects of Lipoic Acid on High-Fat Diet-Induced Alteration of Synaptic Plasticity and Brain Glucose Metabolism: A PET/CT and 13C-NMR Study. Sci Rep. 2017 07 14; 7(1):5391. Liu Z, Patil I, Sancheti H, Yin F, Cadenas E. PMID: 28710347; PMCID: PMC5511189.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    21. Editorial: The Metabolic-Inflammatory Axis in Brain Aging and Neurodegeneration. Front Aging Neurosci. 2017; 9:209. Yin F, Yao J, Brinton RD, Cadenas E. PMID: 28701949; PMCID: PMC5487378.
      View in: PubMed   Mentions: 13  
    22. Lipid quantitation and metabolomics data from vitamin E-deficient and -sufficient zebrafish embryos from 0 to 120 hours-post-fertilization. Data Brief. 2017 Apr; 11:432-441. McDougall M, Choi J, Kim HK, Bobe G, Stevens JF, Cadenas E, Tanguay R, Traber MG. PMID: 28280764; PMCID: PMC5334496.
      View in: PubMed   Mentions: 7  
    23. Lethal dysregulation of energy metabolism during embryonic vitamin E deficiency. Free Radic Biol Med. 2017 03; 104:324-332. McDougall M, Choi J, Kim HK, Bobe G, Stevens JF, Cadenas E, Tanguay R, Traber MG. PMID: 28095320; PMCID: PMC5344700.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    24. Mitochondrial remodeling in the liver following chronic alcohol feeding to rats. Free Radic Biol Med. 2017 01; 102:100-110. Han D, Johnson HS, Rao MP, Martin G, Sancheti H, Silkwood KH, Decker CW, Nguyen KT, Casian JG, Cadenas E, Kaplowitz N. PMID: 27867097; PMCID: PMC5209270.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    25. Introduction to Special Issue on Mitochondrial Redox Signaling in Health and Disease. Free Radic Biol Med. 2016 11; 100:1-4. Bolaños JP, Cadenas E, Duchen MR, Hampton MB, Mann GE, Murphy MP. PMID: 27502830.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    26. Energy metabolism and inflammation in brain aging and Alzheimer's disease. Free Radic Biol Med. 2016 11; 100:108-122. Yin F, Sancheti H, Patil I, Cadenas E. PMID: 27154981; PMCID: PMC5094909.
      View in: PubMed   Mentions: 218     Fields:    Translation:HumansAnimalsCells
    27. Tobacco Smoke-Induced Hepatic Injury with Steatosis, Inflammation, and Impairments in Insulin and Insulin-Like Growth Factor Signaling. J Clin Exp Pathol. 2016 Apr; 6(2). de la Monte SM, Tong M, Agarwal AR, Cadenas E. PMID: 27525191; PMCID: PMC4979551.
      View in: PubMed   Mentions: 3  
    28. Antioxidants, oxidants, and redox impacts on cell function - A tribute to Helmut Sies. Arch Biochem Biophys. 2016 Apr 01; 595:94-9. Cadenas E, Packer L, Traber MG. PMID: 27095223.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    29. Spatial Variations in Vitreous Oxygen Consumption. PLoS One. 2016; 11(3):e0149961. Murali K, Kang D, Nazari H, Scianmarello N, Cadenas E, Tai YC, Kashani A, Humayun M. PMID: 26930281; PMCID: PMC4773158.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    30. Tobacco Smoke Exposure Impairs Brain Insulin/IGF Signaling: Potential Co-Factor Role in Neurodegeneration. J Alzheimers Dis. 2016; 50(2):373-86. Deochand C, Tong M, Agarwal AR, Cadenas E, de la Monte SM. PMID: 26682684.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    31. Tobacco Smoke-Induced Brain White Matter Myelin Dysfunction: Potential Co-Factor Role of Smoking in Neurodegeneration. J Alzheimers Dis. 2016; 50(1):133-48. Yu R, Deochand C, Krotow A, Leão R, Tong M, Agarwal AR, Cadenas E, de la Monte SM. PMID: 26639972; PMCID: PMC5577392.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    32. Cigarette Smoke-Induced Alterations in Frontal White Matter Lipid Profiles Demonstrated by MALDI-Imaging Mass Spectrometry: Relevance to Alzheimer's Disease. J Alzheimers Dis. 2016; 51(1):151-63. Nunez K, Kay J, Krotow A, Tong M, Agarwal AR, Cadenas E, de la Monte SM. PMID: 26836183; PMCID: PMC5575809.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    33. Mitochondrial function in ageing: coordination with signalling and transcriptional pathways. J Physiol. 2016 Apr 15; 594(8):2025-42. Yin F, Sancheti H, Liu Z, Cadenas E. PMID: 26293414; PMCID: PMC4933098.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    34. High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity. PLoS One. 2015; 10(5):e0128274. Liu Z, Patil IY, Jiang T, Sancheti H, Walsh JP, Stiles BL, Yin F, Cadenas E. PMID: 26023930; PMCID: PMC4449222.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    35. Perimenopause as a neurological transition state. Nat Rev Endocrinol. 2015 Jul; 11(7):393-405. Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E. PMID: 26007613; PMCID: PMC9934205.
      View in: PubMed   Mentions: 174     Fields:    Translation:Humans
    36. The perimenopausal aging transition in the female rat brain: decline in bioenergetic systems and synaptic plasticity. Neurobiol Aging. 2015 Jul; 36(7):2282-2295. Yin F, Yao J, Sancheti H, Feng T, Melcangi RC, Morgan TE, Finch CE, Pike CJ, Mack WJ, Cadenas E, Brinton RD. PMID: 25921624; PMCID: PMC4416218.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    37. Mitochondria: the cellular hub of the dynamic coordinated network. Antioxid Redox Signal. 2015 Apr 20; 22(12):961-4. Yin F, Cadenas E. PMID: 25746686; PMCID: PMC4390188.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    38. Preface. Methods Enzymol. 2015; 554:xv. Cadenas E, Packer L. PMID: 25725528.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    39. Polyphenols from green tea prevent antineuritogenic action of Nogo-A via 67-kDa laminin receptor and hydrogen peroxide. J Neurochem. 2015 Jan; 132(1):70-84. Gundimeda U, McNeill TH, Barseghian BA, Tzeng WS, Rayudu DV, Cadenas E, Gopalakrishna R. PMID: 25314656.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    40. Methods in Enzymology. Hydrogen sulfide in redox biology, part B. Preface. Methods Enzymol. 2015; 555:xv. Cadenas E, Packer L. PMID: 25747487.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    41. Astrocytic metabolic and inflammatory changes as a function of age. Aging Cell. 2014 Dec; 13(6):1059-67. Jiang T, Cadenas E. PMID: 25233945; PMCID: PMC4244278.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    42. Hypermetabolic state in the 7-month-old triple transgenic mouse model of Alzheimer's disease and the effect of lipoic acid: a 13C-NMR study. J Cereb Blood Flow Metab. 2014 Nov; 34(11):1749-60. Sancheti H, Patil I, Kanamori K, Díaz Brinton R, Zhang W, Lin AL, Cadenas E. PMID: 25099753; PMCID: PMC4269751.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    43. Short-term cigarette smoke exposure leads to metabolic alterations in lung alveolar cells. Am J Respir Cell Mol Biol. 2014 Aug; 51(2):284-93. Agarwal AR, Yin F, Cadenas E. PMID: 24625219.
      View in: PubMed   Mentions: 58     Fields:    Translation:AnimalsCellsPHPublic Health
    44. Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide. Free Radic Biol Med. 2014 Aug; 73:421-9. Lourenço CF, Santos RM, Barbosa RM, Cadenas E, Radi R, Laranjinha J. PMID: 24887095.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    45. Respiratory substrates regulate S-nitrosylation of mitochondrial proteins through a thiol-dependent pathway. Chem Res Toxicol. 2014 May 19; 27(5):794-804. Chang AH, Sancheti H, Garcia J, Kaplowitz N, Cadenas E, Han D. PMID: 24716714; PMCID: PMC4033640.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    46. Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell. 2014 04; 13(2):367-78. Li B, Iglesias-Pedraz JM, Chen LY, Yin F, Cadenas E, Reddy S, Comai L. PMID: 24757718; PMCID: PMC3999508.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    47. Green tea catechins potentiate the neuritogenic action of brain-derived neurotrophic factor: role of 67-kDa laminin receptor and hydrogen peroxide. Biochem Biophys Res Commun. 2014 Feb 28; 445(1):218-24. Gundimeda U, McNeill TH, Fan TK, Deng R, Rayudu D, Chen Z, Cadenas E, Gopalakrishna R. PMID: 24508265.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    48. Reversal of metabolic deficits by lipoic acid in a triple transgenic mouse model of Alzheimer's disease: a 13C NMR study. J Cereb Blood Flow Metab. 2014 Feb; 34(2):288-96. Sancheti H, Kanamori K, Patil I, Díaz Brinton R, Ross BD, Cadenas E. PMID: 24220168; PMCID: PMC3915206.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    49. Metabolic shift in lung alveolar cell mitochondria following acrolein exposure. Am J Physiol Lung Cell Mol Physiol. 2013 Nov 15; 305(10):L764-73. Agarwal AR, Yin F, Cadenas E. PMID: 24056970.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    50. Lipoic acid restores age-associated impairment of brain energy metabolism through the modulation of Akt/JNK signaling and PGC1α transcriptional pathway. Aging Cell. 2013 Dec; 12(6):1021-31. Jiang T, Yin F, Yao J, Brinton RD, Cadenas E. PMID: 23815272; PMCID: PMC3819405.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    51. Age-dependent modulation of synaptic plasticity and insulin mimetic effect of lipoic acid on a mouse model of Alzheimer's disease. PLoS One. 2013; 8(7):e69830. Sancheti H, Akopian G, Yin F, Brinton RD, Walsh JP, Cadenas E. PMID: 23875003; PMCID: PMC3714252.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    52. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor α (ERRα). J Biol Chem. 2013 Aug 30; 288(35):25007-25024. Li Y, He L, Zeng N, Sahu D, Cadenas E, Shearn C, Li W, Stiles BL. PMID: 23836899; PMCID: PMC3757167.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    53. Metabolic triad in brain aging: mitochondria, insulin/IGF-1 signalling and JNK signalling. Biochem Soc Trans. 2013 Feb 01; 41(1):101-5. Yin F, Jiang T, Cadenas E. PMID: 23356266; PMCID: PMC9934302.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    54. PI3K/AKT signaling regulates bioenergetics in immortalized hepatocytes. Free Radic Biol Med. 2013 Jul; 60:29-40. Li C, Li Y, He L, Agarwal AR, Zeng N, Cadenas E, Stiles BL. PMID: 23376468; PMCID: PMC3654039.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    55. Methods in Enzymology. Hydrogen peroxide and cell signaling, part C. Preface. Methods Enzymol. 2013; 528:xv. Cadenas E, Packer L. PMID: 23849873.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    56. The cellular steady-state of H2O2: latency concepts and gradients. Methods Enzymol. 2013; 527:3-19. Marinho HS, Cyrne L, Cadenas E, Antunes F. PMID: 23830623.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    57. H2O2 delivery to cells: steady-state versus bolus addition. Methods Enzymol. 2013; 526:159-73. Marinho HS, Cyrne L, Cadenas E, Antunes F. PMID: 23791100.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    58. Methods in Enzymology. Hydrogen peroxide and cell signaling, part B. Preface. Methods Enzymol. 2013; 527:xv. Cadenas E, Packer L. PMID: 23830638.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    59. Preface. Hydrogen peroxide and cell signaling, part A. Methods Enzymol. 2013; 526:xv. Cadenas E, Packer L. PMID: 23791105.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    60. Dynamic adaptation of liver mitochondria to chronic alcohol feeding in mice: biogenesis, remodeling, and functional alterations. J Biol Chem. 2012 Dec 07; 287(50):42165-79. Han D, Ybanez MD, Johnson HS, McDonald JN, Mesropyan L, Sancheti H, Martin G, Martin A, Lim AM, Dara L, Cadenas E, Tsukamoto H, Kaplowitz N. PMID: 23086958; PMCID: PMC3516762.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    61. Short-term cigarette smoke exposure induces reversible changes in energy metabolism and cellular redox status independent of inflammatory responses in mouse lungs. Am J Physiol Lung Cell Mol Physiol. 2012 Nov 15; 303(10):L889-98. Agarwal AR, Zhao L, Sancheti H, Sundar IK, Rahman I, Cadenas E. PMID: 23064950.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCellsPHPublic Health
    62. Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration. Antioxid Redox Signal. 2014 Jan 10; 20(2):353-71. Yin F, Boveris A, Cadenas E. PMID: 22793257; PMCID: PMC3887431.
      View in: PubMed   Mentions: 120     Fields:    Translation:HumansAnimalsCells
    63. Mitochondrial thiols in the regulation of cell death pathways. Antioxid Redox Signal. 2012 Dec 15; 17(12):1714-27. Yin F, Sancheti H, Cadenas E. PMID: 22530585; PMCID: PMC3474184.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    64. Chronic expression of RCAN1-1L protein induces mitochondrial autophagy and metabolic shift from oxidative phosphorylation to glycolysis in neuronal cells. J Biol Chem. 2012 Apr 20; 287(17):14088-98. Ermak G, Sojitra S, Yin F, Cadenas E, Cuervo AM, Davies KJ. PMID: 22389495; PMCID: PMC3340208.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    65. Continuous versus cyclic progesterone exposure differentially regulates hippocampal gene expression and functional profiles. PLoS One. 2012; 7(2):e31267. Zhao L, Morgan TE, Mao Z, Lin S, Cadenas E, Finch CE, Pike CJ, Mack WJ, Brinton RD. PMID: 22393359; PMCID: PMC3290616.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    66. Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function. J Neuroendocrinol. 2012 Jan; 24(1):236-48. Irwin RW, Yao J, To J, Hamilton RT, Cadenas E, Brinton RD. PMID: 22070562; PMCID: PMC3264398.
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    67. Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells. Biochim Biophys Acta. 2012 Mar; 1817(3):401-9. Yin F, Sancheti H, Cadenas E. PMID: 22198343; PMCID: PMC3269566.
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    68. Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions. Mol Aspects Med. 2011 Aug; 32(4-6):247-57. Yao J, Rettberg JR, Klosinski LP, Cadenas E, Brinton RD. PMID: 22024249; PMCID: PMC3658304.
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    69. 2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease. PLoS One. 2011; 6(7):e21788. Yao J, Chen S, Mao Z, Cadenas E, Brinton RD. PMID: 21747957; PMCID: PMC3128612.
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    70. Evidence for a pathway that facilitates nitric oxide diffusion in the brain. Neurochem Int. 2011 Aug; 59(1):90-6. Santos RM, Lourenço CF, Gerhardt GA, Cadenas E, Laranjinha J, Barbosa RM. PMID: 21672575.
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    71. Ovarian hormone loss induces bioenergetic deficits and mitochondrial β-amyloid. Neurobiol Aging. 2012 Aug; 33(8):1507-21. Yao J, Irwin R, Chen S, Hamilton R, Cadenas E, Brinton RD. PMID: 21514693; PMCID: PMC3181273.
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    72. Melatonin and steroid hormones activate intermembrane Cu,Zn-superoxide dismutase by means of mitochondrial cytochrome P450. Free Radic Biol Med. 2011 Jun 01; 50(11):1575-81. Iñarrea P, Casanova A, Alava MA, Iturralde M, Cadenas E. PMID: 21397009; PMCID: PMC3144380.
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    73. Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. J Clin Biochem Nutr. 2011 Jan; 48(1):26-32. Packer L, Cadenas E. PMID: 21297908; PMCID: PMC3022059.
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    74. Medroxyprogesterone acetate antagonizes estrogen up-regulation of brain mitochondrial function. Endocrinology. 2011 Feb; 152(2):556-67. Irwin RW, Yao J, Ahmed SS, Hamilton RT, Cadenas E, Brinton RD. PMID: 21159850; PMCID: PMC3157324.
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    75. Estrogen protection against mitochondrial toxin-induced cell death in hippocampal neurons: antagonism by progesterone. Brain Res. 2011 Mar 16; 1379:2-10. Yao J, Chen S, Cadenas E, Brinton RD. PMID: 21134358; PMCID: PMC3200366.
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    76. Protein post-translational modifications in cell signalling and disease. Free Radic Res. 2011 Jan; 45(1):1-2. Galli F, Cadenas E. PMID: 21047170.
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    77. Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates. J Biol Chem. 2010 Dec 17; 285(51):39646-54. Garcia J, Han D, Sancheti H, Yap LP, Kaplowitz N, Cadenas E. PMID: 20937819; PMCID: PMC3000945.
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    78. Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence. Biochim Biophys Acta. 2010 Oct; 1800(10):1121-6. Yao J, Hamilton RT, Cadenas E, Brinton RD. PMID: 20538040; PMCID: PMC3200365.
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    79. Role of nitric oxide-mediated glutathionylation in neuronal function: potential regulation of energy utilization. Biochem J. 2010 Apr 28; 428(1):85-93. Yap LP, Garcia JV, Han DS, Cadenas E. PMID: 20210787; PMCID: PMC3042800.
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    80. In vivo modulation of nitric oxide concentration dynamics upon glutamatergic neuronal activation in the hippocampus. Hippocampus. 2011 Jun; 21(6):622-30. Lourenço CF, Santos R, Barbosa RM, Gerhardt G, Cadenas E, Laranjinha J. PMID: 20169537.
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    81. Dynamic and interacting profiles of *NO and O2 in rat hippocampal slices. Free Radic Biol Med. 2010 Apr 15; 48(8):1044-50. Ledo A, Barbosa R, Cadenas E, Laranjinha J. PMID: 20100565; PMCID: PMC2839026.
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    82. Determination of GSH, GSSG, and GSNO using HPLC with electrochemical detection. Methods Enzymol. 2010; 473:137-47. Yap LP, Sancheti H, Ybanez MD, Garcia J, Cadenas E, Han D. PMID: 20513475; PMCID: PMC3040068.
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    83. Akt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progression. PLoS One. 2009 Oct 21; 4(10):e7523. Antico Arciuch VG, Galli S, Franco MC, Lam PY, Cadenas E, Carreras MC, Poderoso JJ. PMID: 19844585; PMCID: PMC2761088.
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    84. Mitochondrial medicine and therapeutics, Part II. Preface. Adv Drug Deliv Rev. 2009 Nov 30; 61(14):1233. Hamm-Alvarez S, Cadenas E. PMID: 19835920.
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    85. The energy-redox axis in aging and age-related neurodegeneration. Adv Drug Deliv Rev. 2009 Nov 30; 61(14):1283-98. Yap LP, Garcia JV, Han D, Cadenas E. PMID: 19716388; PMCID: PMC2784280.
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    86. Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production. Free Radic Res. 2009 May; 43(5):431-9. Lam PY, Yin F, Hamilton RT, Boveris A, Cadenas E. PMID: 19347761; PMCID: PMC3319075.
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    87. Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging. FEBS Lett. 2009 Apr 02; 583(7):1132-40. Zhou Q, Lam PY, Han D, Cadenas E. PMID: 19272379; PMCID: PMC2672565.
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    88. Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors. Blood. 2009 Jun 04; 113(23):5927-37. Golden EB, Lam PY, Kardosh A, Gaffney KJ, Cadenas E, Louie SG, Petasis NA, Chen TC, Schönthal AH. PMID: 19190249.
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    89. Compromised proteasome degradation elevates neuronal nitric oxide synthase levels and induces apoptotic cell death. Arch Biochem Biophys. 2008 Oct 15; 478(2):181-6. Lam PY, Cadenas E. PMID: 18706882; PMCID: PMC2614914.
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    90. Mitochondrial medicine and mitochondrion-based therapeutics. Adv Drug Deliv Rev. 2008 Oct-Nov; 60(13-14):1437-8. Hamm-Alvarez S, Cadenas E. PMID: 18692102.
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    91. Tumor cell phenotype is sustained by selective MAPK oxidation in mitochondria. PLoS One. 2008 Jun 11; 3(6):e2379. Galli S, Antico Arciuch VG, Poderoso C, Converso DP, Zhou Q, Bal de Kier Joffé E, Cadenas E, Boczkowski J, Carreras MC, Poderoso JJ. PMID: 18545666; PMCID: PMC2398776.
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    92. [Validation of the Spanish version of the QOLIE-10 quality of life in epilepsy questionnaire]. Neurologia. 2008 Apr; 23(3):157-67. Viteri C, Codina M, Cobaleda S, Lahuerta J, Barriga J, Barrera S, Morales MD, grupo de investigadores del estudio de validación del cuestionario QOLIE-10. PMID: 18370335.
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    93. Progesterone and estrogen regulate oxidative metabolism in brain mitochondria. Endocrinology. 2008 Jun; 149(6):3167-75. Irwin RW, Yao J, Hamilton RT, Cadenas E, Brinton RD, Nilsen J. PMID: 18292191; PMCID: PMC2408802.
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    94. Hippocampal mitochondrial dysfunction in rat aging. Am J Physiol Regul Integr Comp Physiol. 2008 Feb; 294(2):R501-9. Navarro A, López-Cepero JM, Bández MJ, Sánchez-Pino MJ, Gómez C, Cadenas E, Boveris A. PMID: 18077512.
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    95. c-Jun N-terminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons. J Neurochem. 2008 Jan; 104(2):325-35. Zhou Q, Lam PY, Han D, Cadenas E. PMID: 17949412.
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    96. Inhibition of cellular proliferation by the genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone is mediated by DNA damage and activation of the ATR signalling pathway. Arch Biochem Biophys. 2007 Dec 15; 468(2):159-66. Vauzour D, Vafeiadou K, Rice-Evans C, Cadenas E, Spencer JP. PMID: 17976513.
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    97. On the biologic role of the reaction of NO with oxidized cytochrome c oxidase. Antioxid Redox Signal. 2007 Oct; 9(10):1569-79. Antunes F, Boveris A, Cadenas E. PMID: 17665969.
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    98. Oxidants and antioxidants revisited. New concepts of oxidative stress. Free Radic Res. 2007 Sep; 41(9):951-2. Packer L, Cadenas E. PMID: 17729110.
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    99. Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis. Biochem J. 2007 Jul 01; 405(1):173-9. Iñarrea P, Moini H, Han D, Rettori D, Aguiló I, Alava MA, Iturralde M, Cadenas E. PMID: 17394422; PMCID: PMC1925252.
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    100. Free radicals and exercise: an introduction. Free Radic Biol Med. 2008 Jan 15; 44(2):123-5. Packer L, Cadenas E, Davies KJ. PMID: 18191747.
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    101. (-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons. J Neurochem. 2007 Jun; 101(6):1596-606. Schroeter H, Bahia P, Spencer JP, Sheppard O, Rattray M, Cadenas E, Rice-Evans C, Williams RJ. PMID: 17298385.
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    102. The mechanism of cytochrome C oxidase inhibition by nitric oxide. Front Biosci. 2007 Jan 01; 12:975-85. Antunes F, Cadenas E. PMID: 17127353.
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    103. Dietary thioproline decreases spontaneous food intake and increases survival and neurological function in mice. Antioxid Redox Signal. 2007 Jan; 9(1):131-41. Navarro A, Sánchez-Pino MJ, Gómez C, Bández MJ, Cadenas E, Boveris A. PMID: 17115892.
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    104. Hemodynamics influences vascular peroxynitrite formation: Implication for low-density lipoprotein apo-B-100 nitration. Free Radic Biol Med. 2007 Feb 15; 42(4):519-29. Hsiai TK, Hwang J, Barr ML, Correa A, Hamilton R, Alavi M, Rouhanizadeh M, Cadenas E, Hazen SL. PMID: 17275684; PMCID: PMC2561143.
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    105. The intracellular genistein metabolite 5,7,3',4'-tetrahydroxyisoflavone mediates G2-M cell cycle arrest in cancer cells via modulation of the p38 signaling pathway. Free Radic Biol Med. 2006 Oct 15; 41(8):1225-39. Nguyen DT, Hernandez-Montes E, Vauzour D, Schönthal AH, Rice-Evans C, Cadenas E, Spencer JP. PMID: 17015169.
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    106. Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor. Proc Natl Acad Sci U S A. 2005 Nov 29; 102(48):17483-8. Ledo A, Barbosa RM, Gerhardt GA, Cadenas E, Laranjinha J. PMID: 16293699; PMCID: PMC1297656.
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    107. Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione. Biochemistry. 2005 Sep 13; 44(36):11986-96. Han D, Canali R, Garcia J, Aguilera R, Gallaher TK, Cadenas E. PMID: 16142896.
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    108. Mitochondrial nitric oxide synthase. Trends Pharmacol Sci. 2005 Apr; 26(4):190-5. Ghafourifar P, Cadenas E. PMID: 15808343.
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    109. Redox activation of mitochondrial intermembrane space Cu,Zn-superoxide dismutase. Biochem J. 2005 Apr 01; 387(Pt 1):203-9. Iñarrea P, Moini H, Rettori D, Han D, Martínez J, García I, Fernández-Vizarra E, Iturralde M, Cadenas E. PMID: 15537389; PMCID: PMC1134948.
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    110. Redox interactions of nitric oxide with dopamine and its derivatives. Toxicology. 2005 Mar 15; 208(2):207-12. Antunes F, Nunes C, Laranjinha J, Cadenas E. PMID: 15691585.
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    111. HNE and Further Lipid Peroxidation Products. Biofactors. 2005; 24(1-4):1-4. Siems W, Grune T, Sommerburg O, Flohé L, Cadenas E. PMID: 16403958.
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    112. Leucoisoprenochrome-o-semiquinone formation in freshly isolated adult rat cardiomyocytes. Chem Res Toxicol. 2004 Dec; 17(12):1584-90. Remião F, Rettori D, Han D, Carvalho F, Bastos ML, Cadenas E. PMID: 15606133.
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    113. On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide. Proc Natl Acad Sci U S A. 2004 Nov 30; 101(48):16774-9. Antunes F, Boveris A, Cadenas E. PMID: 15546991; PMCID: PMC534717.
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    114. Kinetic analysis of thapsigargin-induced thymocyte apoptosis. Free Radic Biol Med. 2004 Nov 01; 37(9):1490-8. Bustamante J, Di Libero E, Fernandez-Cobo M, Monti N, Cadenas E, Boveris A. PMID: 15454289.
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    115. Mitochondrial free radical production and cell signaling. Mol Aspects Med. 2004 Feb-Apr; 25(1-2):17-26. Cadenas E. PMID: 15051313.
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    116. c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochem J. 2003 Jun 01; 372(Pt 2):359-69. Schroeter H, Boyd CS, Ahmed R, Spencer JP, Duncan RF, Rice-Evans C, Cadenas E. PMID: 12614194; PMCID: PMC1223409.
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    117. Voltage-dependent anion channels control the release of the superoxide anion from mitochondria to cytosol. J Biol Chem. 2003 Feb 21; 278(8):5557-63. Han D, Antunes F, Canali R, Rettori D, Cadenas E. PMID: 12482755.
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    118. Mitochondrial damage by nitric oxide is potentiated by dopamine in PC12 cells. Biochim Biophys Acta. 2002 Dec 02; 1556(2-3):233-8. Antunes F, Han D, Rettori D, Cadenas E. PMID: 12460681.
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    119. Relative contributions of heart mitochondria glutathione peroxidase and catalase to H(2)O(2) detoxification in in vivo conditions. Free Radic Biol Med. 2002 Nov 01; 33(9):1260-7. Antunes F, Han D, Cadenas E. PMID: 12398934.
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    120. Reverse micelles in organic solvents: a medium for the biotechnological use of extreme halophilic enzymes at low salt concentration. Archaea. 2002 Sep; 1(2):105-11. Marhuenda-Egea FC, Piera-Velázquez S, Cadenas C, Cadenas E. PMID: 15803648; PMCID: PMC2685557.
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    121. Pathways of dopamine oxidation mediated by nitric oxide. Free Radic Biol Med. 2002 Sep 01; 33(5):685-90. Rettori D, Tang Y, Dias LC, Cadenas E. PMID: 12208355.
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    122. MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide. Neurobiol Aging. 2002 Sep-Oct; 23(5):861-80. Schroeter H, Boyd C, Spencer JP, Williams RJ, Cadenas E, Rice-Evans C. PMID: 12392791.
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    123. The modulation of mitochondrial nitric-oxide synthase activity in rat brain development. J Biol Chem. 2002 Nov 08; 277(45):42447-55. Riobo NA, Melani M, Sanjuan N, Fiszman ML, Gravielle MC, Carreras MC, Cadenas E, Poderoso JJ. PMID: 12202479.
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    124. Mechanism of adaptation of an atypical alkaline p-nitrophenyl phosphatase from the archaeon Halobacterium salinarum at low-water environments. Biotechnol Bioeng. 2002 Jun 05; 78(5):497-502. Marhuenda-Egea FC, Piera-Velázquez S, Cadenas C, Cadenas E. PMID: 12115118.
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    125. Increased stability of malate dehydrogenase from Halobacterium salinarum at low salt concentration in reverse micelles. Extremophiles. 2002 Oct; 6(5):407-12. Piera-Velázquez S, Marhuenda-Egea F, Cadenas E. PMID: 12382117.
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    126. Oxidation of DOPAC by nitric oxide: effect of superoxide dismutase. J Neurochem. 2002 May; 81(4):892-900. Laranjinha J, Cadenas E. PMID: 12065648.
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    127. Nitric oxide and cell signaling pathways in mitochondrial-dependent apoptosis. Biol Chem. 2002 Mar-Apr; 383(3-4):411-23. Boyd CS, Cadenas E. PMID: 12033432.
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    128. An extreme halophilic enzyme active at low salt in reversed micelles. J Biotechnol. 2002 Feb 14; 93(2):159-64. Marhuenda-Egea FC, Piera-Velázquez S, Cadenas C, Cadenas E. PMID: 11738722.
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    129. The reaction of nitric oxide with 6-hydroxydopamine: implications for Parkinson's disease. Free Radic Biol Med. 2002 Jan 15; 32(2):115-21. Riobó NA, Schöpfer FJ, Boveris AD, Cadenas E, Poderoso JJ. PMID: 11796199.
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    130. Mitochondrial superoxide anion production and release into intermembrane space. Methods Enzymol. 2002; 349:271-80. Han D, Antunes F, Daneri F, Cadenas E. PMID: 11912916.
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    131. Impact of water-dispersible beadlets as a vehicle for the delivery of carotenoids to cultured cells. Biofactors. 2002; 16(3-4):83-91. Shahrzad S, Cadenas E, Sevanian A, Packer L. PMID: 14530596.
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    132. Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation. Biochem J. 2001 Oct 01; 359(Pt 1):139-45. Riobó NA, Clementi E, Melani M, Boveris A, Cadenas E, Moncada S, Poderoso JJ. PMID: 11563977; PMCID: PMC1222129.
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    133. Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture. Biochem J. 2001 Jun 01; 356(Pt 2):549-55. Antunes F, Cadenas E, Brunk UT. PMID: 11368784; PMCID: PMC1221868.
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    134. Stability of an extreme halophilic alkaline phosphatase from Halobacterium salinarium in non-conventional medium. J Biotechnol. 2001 May 18; 87(3):255-61. Marhuenda-Egea FC, Piera-Velázquez S, Cadenas C, Cadenas E. PMID: 11334667.
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    135. Cellular titration of apoptosis with steady state concentrations of H(2)O(2): submicromolar levels of H(2)O(2) induce apoptosis through Fenton chemistry independent of the cellular thiol state. Free Radic Biol Med. 2001 May 01; 30(9):1008-18. Antunes F, Cadenas E. PMID: 11316581.
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    136. Kinetic regulation of an alkaline p-nitrophenylphosphate phosphatase from Halobacterium salinarum in low water system by Mn2+ and monovalent cations. FEMS Microbiol Lett. 2001 May 01; 198(2):111-5. Marhuenda-Egea FC, Piera-Velázquez S, Cadenas C, Cadenas E. PMID: 11430399.
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    137. Mitochondrial respiratory chain-dependent generation of superoxide anion and its release into the intermembrane space. Biochem J. 2001 Jan 15; 353(Pt 2):411-6. Han D, Williams E, Cadenas E. PMID: 11139407; PMCID: PMC1221585.
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    138. Analysis of the pathways of nitric oxide utilization in mitochondria. Free Radic Res. 2000 Dec; 33(6):747-56. Cadenas E, Poderoso JJ, Antunes F, Boveris A. PMID: 11237097.
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    139. Mitochondrial production of hydrogen peroxide regulation by nitric oxide and the role of ubisemiquinone. IUBMB Life. 2000 Oct-Nov; 50(4-5):245-50. Boveris A, Cadenas E. PMID: 11327317.
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    140. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med. 2000 Aug; 29(3-4):222-30. Cadenas E, Davies KJ. PMID: 11035250.
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    141. Oxidation of ubiquinol by peroxynitrite: implications for protection of mitochondria against nitrosative damage. Biochem J. 2000 Jul 01; 349(Pt 1):35-42. Schöpfer F, Riobó N, Carreras MC, Alvarez B, Radi R, Boveris A, Cadenas E, Poderoso JJ. PMID: 10861208; PMCID: PMC1221117.
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    142. Estimation of H2O2 gradients across biomembranes. FEBS Lett. 2000 Jun 16; 475(2):121-6. Antunes F, Cadenas E. PMID: 10858501.
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    143. p21WAF1 regulates anchorage-independent growth of HCT116 colon carcinoma cells via E-cadherin expression. Cancer Res. 2000 Jan 01; 60(1):156-63. Mueller S, Cadenas E, Schönthal AH. PMID: 10646868.
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    144. Regulation of mitochondrial respiration by oxygen and nitric oxide. Ann N Y Acad Sci. 2000; 899:121-35. Boveris A, Costa LE, Poderoso JJ, Carreras MC, Cadenas E. PMID: 10863534.
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    145. Mitochondrial oxidative stress: a self-propagating process with implications for signaling cascades. Biofactors. 2000; 11(1-2):43-5. Poderoso JJ, Boveris A, Cadenas E. PMID: 10705957.
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    146. Formation of electronically excited states during the oxidation of arachidonic acid by prostaglandin endoperoxide synthase. Methods Enzymol. 2000; 319:67-77. Cadenas E, Sies H. PMID: 10907500.
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    147. The regulation of mitochondrial oxygen uptake by redox reactions involving nitric oxide and ubiquinol. J Biol Chem. 1999 Dec 31; 274(53):37709-16. Poderoso JJ, Lisdero C, Schöpfer F, Riobó N, Carreras MC, Cadenas E, Boveris A. PMID: 10608829.
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    148. Redox cycles of caffeic acid, alpha-tocopherol, and ascorbate: implications for protection of low-density lipoproteins against oxidation. IUBMB Life. 1999 Jul; 48(1):57-65. Laranjinha J, Cadenas E. PMID: 10791916.
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    149. The reaction of nitric oxide with ubiquinol: kinetic properties and biological significance. Free Radic Biol Med. 1999 Apr; 26(7-8):925-35. Poderoso JJ, Carreras MC, Schöpfer F, Lisdero CL, Riobó NA, Giulivi C, Boveris AD, Boveris A, Cadenas E. PMID: 10232836.
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    150. Regulation of mitochondrial respiration by adenosine diphosphate, oxygen, and nitric oxide. Methods Enzymol. 1999; 301:188-98. Boveris A, Costa LE, Cadenas E, Poderoso JJ. PMID: 9919567.
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    151. The role of mitochondrial glutathione in DNA base oxidation. Biochim Biophys Acta. 1998 Sep 07; 1366(3):265-74. Giulivi C, Cadenas E. PMID: 9814840.
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    152. Role of p53 in aziridinylbenzoquinone-induced p21waf1 expression. Oncogene. 1998 Jul 23; 17(3):357-65. Wu RC, Hohenstein A, Park JM, Qiu X, Mueller S, Cadenas E, Schönthal AH. PMID: 9690517.
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    153. Oxidation of adrenaline by ferrylmyoglobin. Free Radic Biol Med. 1998 Jul 15; 25(2):175-83. Giulivi C, Cadenas E. PMID: 9667493.
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    154. Extracellular activation of fluorinated aziridinylbenzoquinone in HT29 cells EPR studies. Chem Biol Interact. 1998 Jun 05; 113(3):191-204. Giulivi C, Cadenas E. PMID: 9717518.
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    155. The lag phase. Free Radic Res. 1998 Jun; 28(6):601-9. Cadenas E, Sies H. PMID: 9736312.
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    156. Anticancer quinones induce pRb-preventable G2/M cell cycle arrest and apoptosis. Free Radic Biol Med. 1998 Mar 15; 24(5):848-54. Qiu XB, Schönthal AH, Cadenas E. PMID: 9586815.
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    157. Reactions of halogen-substituted aziridinylbenzoquinones with glutathione. Formation of diglutathionyl conjugates and semiquinones. Chem Biol Interact. 1998 Jan 30; 108(3):137-54. Giulivi C, Forlin A, Bellin S, Cadenas E. PMID: 9528686.
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    158. Heme protein radicals: formation, fate, and biological consequences. Free Radic Biol Med. 1998 Jan 15; 24(2):269-79. Giulivi C, Cadenas E. PMID: 9433902.
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    159. Nitric oxide regulates oxygen uptake and hydrogen peroxide release by the isolated beating rat heart. Am J Physiol. 1998 01; 274(1):C112-9. Poderoso JJ, Peralta JG, Lisdero CL, Carreras MC, Radisic M, Schöpfer F, Cadenas E, Boveris A. PMID: 9458719.
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    160. The role of NAD(P)H:quinone oxidoreductase in quinone-mediated p21 induction in human colon carcinoma cells. Arch Biochem Biophys. 1997 Oct 15; 346(2):241-51. Qiu XB, Cadenas E. PMID: 9343371.
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    161. Basic mechanisms of antioxidant activity. Biofactors. 1997; 6(4):391-7. Cadenas E. PMID: 9388304.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    162. Induction of p21 mediated by reactive oxygen species formed during the metabolism of aziridinylbenzoquinones by HCT116 cells. J Biol Chem. 1996 Dec 13; 271(50):31915-21. Qiu X, Forman HJ, Schönthal AH, Cadenas E. PMID: 8943236.
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    163. The metabolism of tyramine by monoamine oxidase A/B causes oxidative damage to mitochondrial DNA. Arch Biochem Biophys. 1996 Nov 15; 335(2):295-304. Hauptmann N, Grimsby J, Shih JC, Cadenas E. PMID: 8914926.
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    164. Measurement of nitric oxide and hydrogen peroxide production from human neutrophils. Methods Enzymol. 1996; 269:65-75. Carreras MC, Poderoso JJ, Cadenas E, Boveris A. PMID: 8791638.
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    165. Enzymic- and thiol-mediated activation of halogen-substituted diaziridinylbenzoquinones: redox transitions of the semiquinone and semiquinone-thioether species. Free Radic Biol Med. 1995 Mar; 18(3):525-36. Goin J, Giulivi C, Butler J, Cadenas E. PMID: 9101243.
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    166. Hydroxyl radical generation during mitochondrial electron transfer and the formation of 8-hydroxydesoxyguanosine in mitochondrial DNA. Arch Biochem Biophys. 1995 Feb 01; 316(2):909-16. Giulivi C, Boveris A, Cadenas E. PMID: 7864650.
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    167. Antioxidant and prooxidant functions of DT-diaphorase in quinone metabolism. Biochem Pharmacol. 1995 Jan 18; 49(2):127-40. Cadenas E. PMID: 7530954.
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    168. Thiyl radical formation during thiol oxidation by ferrylmyoglobin. Methods Enzymol. 1995; 251:106-16. Cadenas E. PMID: 7651190.
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    169. Kinetic mechanism of Halobacterium halobium Mn(2+)-activated alkaline phosphatase. Biochem Mol Biol Int. 1994 Dec; 34(6):1109-20. Bonet ML, Llorca FI, Cadenas E. PMID: 7696983.
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    170. One- and two-electron reduction of 2-methyl-1,4-naphthoquinone bioreductive alkylating agents: kinetic studies, free-radical production, thiol oxidation and DNA-strand-break formation. Biochem J. 1994 Jul 01; 301 ( Pt 1):21-30. Giulivi C, Cadenas E. PMID: 8037673; PMCID: PMC1137137.
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    171. Reactivity of metmyoglobin towards phospholipid hydroperoxides. Free Radic Biol Med. 1994 May; 16(5):661-7. Maiorino M, Ursini F, Cadenas E. PMID: 8026809.
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    172. Ferrylmyoglobin: formation and chemical reactivity toward electron-donating compounds. Methods Enzymol. 1994; 233:189-202. Giulivi C, Cadenas E. PMID: 8015456.
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    173. The reaction of ascorbic acid with different heme iron redox states of myoglobin. Antioxidant and prooxidant aspects. FEBS Lett. 1993 Oct 18; 332(3):287-90. Giulivi C, Cadenas E. PMID: 8405472.
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    174. Redox cycling of MPP+: evidence for a new mechanism involving hydride transfer with xanthine oxidase, aldehyde dehydrogenase, and lipoamide dehydrogenase. Free Radic Biol Med. 1993 Aug; 15(2):169-79. Klaidman LK, Adams JD, Leung AC, Kim SS, Cadenas E. PMID: 8397142.
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    175. Inhibition of protein radical reactions of ferrylmyoglobin by the water-soluble analog of vitamin E, Trolox C. Arch Biochem Biophys. 1993 May 15; 303(1):152-8. Giulivi C, Cadenas E. PMID: 8489259.
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    176. The interaction of Trolox C, a water-soluble vitamin E analog, with ferrylmyoglobin: reduction of the oxoferryl moiety. Arch Biochem Biophys. 1992 Dec; 299(2):302-12. Giulivi C, Romero FJ, Cadenas E. PMID: 1444470.
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    177. Involvement of thiol groups in the reaction mechanism of Mn(2+)-activated alkaline p-nitrophenylphosphate phosphatase of the extreme halophilic archaebacterium Halobacterium halobium. Biochem Int. 1992 Dec; 28(4):633-41. Bonet ML, Llorca FI, Cadenas E. PMID: 1336386.
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    178. Reduction of sperm whale ferrylmyoglobin by endogenous reducing agents: potential reducible loci of ferrylmyoglobin. Free Radic Biol Med. 1992 Oct; 13(4):449-54. Arduini A, Mancinelli G, Radatti GL, Damonti W, Hochstein P, Cadenas E. PMID: 1398221.
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    179. Thiol oxidation coupled to DT-diaphorase-catalysed reduction of diaziquone. Reductive and oxidative pathways of diaziquone semiquinone modulated by glutathione and superoxide dismutase. Biochem J. 1992 Sep 01; 286 ( Pt 2):481-90. Ordoñez ID, Cadenas E. PMID: 1530580; PMCID: PMC1132923.
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    180. MPP+ redox cycling: a new mechanism involving hydride transfer. Ann N Y Acad Sci. 1992 May 11; 648:239-40. Adams JD, Klaidman LK, Cadenas E. PMID: 1637049.
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    181. Alkaline p-nitrophenylphosphate phosphatase activity from Halobacterium halobium. Selective activation by manganese and effect of other divalent cations. Int J Biochem. 1992 May; 24(5):839-45. Bonet ML, Llorca FI, Cadenas E. PMID: 1317306.
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    182. Possible mechanism of inhibition of nitrite-induced oxidation of oxyhemoglobin by ergothioneine and uric acid. Arch Biochem Biophys. 1992 May 01; 294(2):398-402. Arduini A, Mancinelli G, Radatti GL, Hochstein P, Cadenas E. PMID: 1567195.
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    183. The reactivity of thiols and disulfides with different redox states of myoglobin. Redox and addition reactions and formation of thiyl radical intermediates. J Biol Chem. 1992 Jan 25; 267(3):1680-8. Romero FJ, Ordoñez I, Arduini A, Cadenas E. PMID: 1309791.
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    184. Pro- and antioxidant functions of quinones and quinone reductases in mammalian cells. Adv Enzymol Relat Areas Mol Biol. 1992; 65:97-146. Cadenas E, Hochstein P, Ernster L. PMID: 1570770.
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    185. Glutathionyl- and hydroxyl radical formation coupled to the redox transitions of 1,4-naphthoquinone bioreductive alkylating agents during glutathione two-electron reductive addition. Arch Biochem Biophys. 1991 Aug 01; 288(2):386-96. Goin J, Gibson DD, McCay PB, Cadenas E. PMID: 1654832.
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    186. Analysis of the kinetic mechanism of halophilic NADP-dependent glutamate dehydrogenase. Biochim Biophys Acta. 1990 Dec 05; 1041(3):305-10. Bonete MJ, Camacho ML, Cadenas E. PMID: 1980084.
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    187. Ferrylmyoglobin-catalyzed linoleic acid peroxidation. Arch Biochem Biophys. 1990 Aug 15; 281(1):163-9. Galaris D, Sevanian A, Cadenas E, Hochstein P. PMID: 2383021.
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    188. Quinoid compounds: high-performance liquid chromatography with electrochemical detection. Methods Enzymol. 1990; 186:180-96. Cadenas E, Ernster L. PMID: 2172704.
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    189. Effect of superoxide dismutase on the autoxidation of substituted hydro- and semi-naphthoquinones. Chem Biol Interact. 1990; 73(1):53-76. Ollinger K, Buffinton GD, Ernster L, Cadenas E. PMID: 2105855.
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    190. Effect of superoxide dismutase on the autoxidation of hydroquinones formed during DT-diaphorase catalysis and glutathione nucleophilic addition. Adv Exp Med Biol. 1990; 264:37-44. Cadenas E, Ernster L. PMID: 2244516.
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    191. Effect of glutathione on the redox transitions of naphthohydroquinone derivatives formed during DT-diaphorase catalysis. Free Radic Res Commun. 1990; 8(4-6):271-85. Llopis J, Ernster L, Cadenas E. PMID: 2113028.
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    192. DT-diaphorase: purification, properties, and function. Methods Enzymol. 1990; 186:287-301. Lind C, Cadenas E, Hochstein P, Ernster L. PMID: 2233301.
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    193. Study of the redox properties of naphthazarin (5,8-dihydroxy-1,4-naphthoquinone) and its glutathionyl conjugate in biological reactions: one- and two-electron enzymatic reduction. Arch Biochem Biophys. 1989 Dec; 275(2):514-30. Ollinger K, Llopis J, Cadenas E. PMID: 2512857.
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    194. Redox cycling of myoglobin and ascorbate: a potential protective mechanism against oxidative reperfusion injury in muscle. Arch Biochem Biophys. 1989 Sep; 273(2):497-504. Galaris D, Cadenas E, Hochstein P. PMID: 2774564.
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    195. Pulse radiolysis study of the reactivity of Trolox C phenoxyl radical with superoxide anion. FEBS Lett. 1989 Aug 14; 253(1-2):235-8. Cadenas E, Merényi G, Lind J. PMID: 2547658.
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    196. Lipid peroxidation during the oxidation of haemoproteins by hydroperoxides. Relation to electronically excited state formation. J Biolumin Chemilumin. 1989 Jul; 4(1):208-18. Cadenas E. PMID: 2678914.
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    197. Mechanisms of reoxygenation injury in myocardial infarction: implications of a myoglobin redox cycle. Biochem Biophys Res Commun. 1989 May 15; 160(3):1162-8. Galaris D, Eddy L, Arduini A, Cadenas E, Hochstein P. PMID: 2730642.
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    198. Kinetic mechanism of Halobacterium halobium NAD+-glutamate dehydrogenase. Biochim Biophys Acta. 1989 Feb 24; 990(2):150-5. Bonete MJ, Camacho ML, Cadenas E. PMID: 2917175.
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    199. DT-diaphorase-catalysed reduction of 1,4-naphthoquinone derivatives and glutathionyl-quinone conjugates. Effect of substituents on autoxidation rates. Biochem J. 1989 Jan 15; 257(2):561-71. Buffinton GD, Ollinger K, Brunmark A, Cadenas E. PMID: 2494985; PMCID: PMC1135615.
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    200. 1,4-Reductive addition of glutathione to quinone epoxides. Mechanistic studies with h.p.l.c. with electrochemical detection under anaerobic and aerobic conditions. Evaluation of chemical reactivity in terms of autoxidation reactions. Free Radic Biol Med. 1989; 6(2):149-65. Brunmark A, Cadenas E. PMID: 2707617.
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    201. Antioxidant activity of 5-hydroxytryptophan, 5-hydroxyindole, and DOPA against microsomal lipid peroxidation and its dependence on vitamin E. Free Radic Res Commun. 1989; 6(1):11-7. Cadenas E, Simic MG, Sies H. PMID: 2498167.
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    202. Glutathione-dependent reduction of peroxides during ferryl- and met-myoglobin interconversion: a potential protective mechanism in muscle. Free Radic Biol Med. 1989; 6(5):473-8. Galaris D, Cadenas E, Hochstein P. PMID: 2744579.
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    203. Biochemistry of oxygen toxicity. Annu Rev Biochem. 1989; 58:79-110. Cadenas E. PMID: 2673022.
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    204. Redox and addition chemistry of quinoid compounds and its biological implications. Free Radic Biol Med. 1989; 7(4):435-77. Brunmark A, Cadenas E. PMID: 2691341.
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    205. Hydroperoxide-induced chemiluminescence in rabbit lungs: role of arachidonic acid enzymes. J Appl Physiol (1985). 1988 Sep; 65(3):1340-50. Knoblauch AL, Paky A, Michael JR, Kutner ME, Cadenas E, Sies H, Adkinson NF, Gurtner GH. PMID: 3141352.
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    206. An experimental model system for leishmaniasis. Effects of porphyrin-compounds and menadione on Leishmania parasites engulfed by cultured macrophages. APMIS. 1988 Jun; 96(6):543-51. Abok K, Cadenas E, Brunk U. PMID: 3395481.
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    207. Co-oxidation of salicylate and cholesterol during the oxidation of metmyoglobin by H2O2. Arch Biochem Biophys. 1988 Apr; 262(1):221-31. Galaris D, Mira D, Sevanian A, Cadenas E, Hochstein P. PMID: 3355168.
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    208. Inhibition of the mitochondrial F1-ATPase by rose bengal mediated photooxidation. Interaction of the Fe2+ chelate of bathophenanthroline with the sensitizer. Acta Chem Scand B. 1988 Mar; 42(3):175-82. Glaser E, Cadenas E, Andell S, Ernster L. PMID: 2899936.
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    209. One-electron transfer reactions of diquat radical to different reduction intermediates of oxygen. Formation of hydroxyl radical and electronically excited states. Free Radic Biol Med. 1988; 5(3):155-63. Mira D, Brunk U, Boveris A, Cadenas E. PMID: 2855422.
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    210. Reduction of ferryl- and metmyoglobin to ferrous myoglobin by menadione-glutathione conjugate. Spectrophotometric studies under aerobic and anaerobic conditions. Chem Biol Interact. 1988; 66(3-4):205-22. Buffinton G, Mira D, Galaris D, Hochstein P, Cadenas E. PMID: 3396121.
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    211. Reduction of ferrylmyoglobin to metmyoglobin by quinonoid compounds. Chem Biol Interact. 1988; 66(3-4):233-50. Buffinton G, Cadenas E. PMID: 3396122.
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    212. Reductive addition of glutathione to p-benzoquinone, 2-hydroxy-p-benzoquinone, and p-benzoquinone epoxides. Effect of the hydroxy- and glutathionyl substituents on p-benzohydroquinone autoxidation. Chem Biol Interact. 1988; 68(3-4):273-98. Brunmark A, Cadenas E. PMID: 3214888.
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    213. Effect of superoxide dismutase on the autoxidation of various hydroquinones--a possible role of superoxide dismutase as a superoxide:semiquinone oxidoreductase. Free Radic Biol Med. 1988; 5(2):71-9. Cadenas E, Mira D, Brunmark A, Lind C, Segura-Aguilar J, Ernster L. PMID: 2855420.
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    214. Oxidation of quinones by H2O2: formation of epoxy- and hydroxyquinone adducts and electronically excited states. Basic Life Sci. 1988; 49:81-6. Brunmark A, Cadenas E. PMID: 3074797.
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    215. DT-diaphorase-catalyzed two-electron reduction of various p-benzoquinone- and 1,4-naphthoquinone epoxides. Free Radic Biol Med. 1988; 5(3):133-43. Brunmark A, Cadenas E, Segura-Aguilar J, Lind C, Ernster L. PMID: 3151071.
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    216. The potential intermediate role of lysosomes in oxygen free radical pathology. Review article. APMIS. 1988 Jan; 96(1):3-13. Brunk U, Cadenas E. PMID: 3278721.
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    217. DT-diaphorase-catalyzed two-electron reduction of quinone epoxides. Free Radic Biol Med. 1987; 3(3):181-8. Brunmark A, Cadenas E, Lind C, Segura-Aguilar J, Ernster L. PMID: 3117624.
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    218. Hydroperoxide metabolism in vitamin E-deficient hepatocytes. Studies on low-level chemiluminescence, lipid peroxidation, and glutathione status. Pharmacol Ther. 1987; 33(1):179-86. Romero FJ, Cadenas E. PMID: 3628471.
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    219. Electronically excited state generation during the reaction of p-benzoquinone with H2O2. Relation to product formation: 2-OH- and 2,3-epoxy-p-benzoquinone. The effect of glutathione. Free Radic Biol Med. 1987; 3(3):169-80. Brunmark A, Cadenas E. PMID: 3666518.
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    220. Reactive oxygen intermediates in biochemistry. Annu Rev Biochem. 1986; 55:137-66. Naqui A, Chance B, Cadenas E. PMID: 3017191.
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    221. The relation of free radical production to hyperoxia. Annu Rev Physiol. 1986; 48:703-19. Jamieson D, Chance B, Cadenas E, Boveris A. PMID: 3010832.
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    222. Oxidative stress: damage to intact cells and organs. Philos Trans R Soc Lond B Biol Sci. 1985 Dec 17; 311(1152):617-31. Sies H, Cadenas E. PMID: 2869521.
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    223. Oxidative stress: excited oxygen species and enzyme activity. Adv Enzyme Regul. 1985; 23:217-37. Cadenas E, Sies H. PMID: 3907304.
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    224. Biological chemiluminescence. Photochem Photobiol. 1984 Dec; 40(6):823-30. Cadenas E. PMID: 6395146.
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    225. Evaluation of alpha-tocopherol antioxidant activity in microsomal lipid peroxidation as detected by low-level chemiluminescence. Biochem J. 1984 Nov 01; 223(3):755-9. Cadenas E, Ginsberg M, Rabe U, Sies H. PMID: 6508739; PMCID: PMC1144359.
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    226. A novel biologically active seleno-organic compound--I. Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ 51 (Ebselen). Biochem Pharmacol. 1984 Oct 15; 33(20):3235-9. Müller A, Cadenas E, Graf P, Sies H. PMID: 6487370.
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    227. Low-level chemiluminescence as an indicator of singlet molecular oxygen in biological systems. Methods Enzymol. 1984; 105:221-31. Cadenas E, Sies H. PMID: 6328183.
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    228. Antioxidant effect of diethyldithiocarbamate on microsomal lipid peroxidation assessed by low-level chemiluminescence and alkane production. FEBS Lett. 1983 Dec 12; 164(2):371-4. Bartoli GM, Müller A, Cadenas E, Sies H. PMID: 6317459.
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    229. Effects of 4-hydroxynonenal on isolated hepatocytes. Studies on chemiluminescence response, alkane production and glutathione status. Biochem J. 1983 Aug 15; 214(2):479-87. Cadenas E, Müller A, Brigelius R, Esterbauer H, Sies H. PMID: 6688523; PMCID: PMC1152270.
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    230. Cellular redox changes and response to drugs and toxic agents. Fundam Appl Toxicol. 1983 Jul-Aug; 3(4):200-8. Sies H, Brigelius R, Wefers H, Müller A, Cadenas E. PMID: 6354819.
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    231. Singlet oxygen formation detected by low-level chemiluminescence during enzymatic reduction of prostaglandin G2 to H2. Hoppe Seylers Z Physiol Chem. 1983 May; 364(5):519-28. Cadenas E, Sies H, Nastainczyk W, Ullrich V. PMID: 6409778.
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    232. Oxene donors yield low-level chemiluminescence with microsomes and isolated cytochrome P-450. Eur J Biochem. 1983 Jan 17; 130(1):117-21. Cadenas E, Sies H, Graf H, Ullrich V. PMID: 6825683.
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    233. Evidence for lipid peroxidation by paraquat in the perfused rat lung. J Lab Clin Med. 1983 Jan; 101(1):66-73. Aldrich TK, Fisher AB, Cadenas E, Chance B. PMID: 6848615.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    234. Paraquat-induced chemiluminescence of microsomal fractions. Biochem Pharmacol. 1983 Jan 01; 32(1):147-50. Cadenas E, Brigelius R, Sies H. PMID: 6830610.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    235. Low level chemiluminescence of liver microsomal fractions initiated by tert-butyl hydroperoxide. Relation to microsomal hemoproteins, oxygen dependence, and lipid peroxidation. Eur J Biochem. 1982 May 17; 124(2):349-56. Cadenas E, Sies H. PMID: 7094917.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    236. Influence of pH on the allosteric properties of lactate dehydrogenase activity of Phycomyces blakesleeanus. Biochem J. 1982 May 01; 203(2):393-400. De Arriaga D, Soler J, Cadenas E. PMID: 7115294; PMCID: PMC1158242.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    237. Lactate dehydrogenase in Phycomyces blakesleeanus. Biochem J. 1982 May 01; 203(2):383-91. Soler J, De Arriaga D, Busto F, Cadenas E. PMID: 7115293; PMCID: PMC1158241.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    238. The role of glutathione in hepatic hydroperoxide metabolism. Biochem Soc Trans. 1982 Apr; 10(2):79-80. Sies H, Akerboom TP, Cadenas E. PMID: 7067916.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    239. Active oxygen metabolites and their action in the hepatocyte. Studies on chemiluminescence responses and alkane production. Agents Actions Suppl. 1982; 11:203-16. Cadenas E, Wefers H, Müller A, Brigelius R, Sies H. PMID: 6960650.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    240. Low-level chemiluminescence of isolated hepatocytes. Eur J Biochem. 1981 Oct; 119(3):531-6. Cadenas E, Wefers H, Sies H. PMID: 7308199.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    241. Oxygen- or organic hydroperoxide-induced chemiluminescence of brain and liver homogenates. Biochem J. 1981 Sep 15; 198(3):645-54. Cadenas E, Varsavsky AI, Boveris A, Chance B. PMID: 7326030; PMCID: PMC1163313.
      View in: PubMed   Mentions: 21     Fields:    Translation:Animals
    242. Ultraweak chemiluminescence: a sensitive assay for oxidative radical reactions. Fed Proc. 1981 Feb; 40(2):195-8. Boveris A, Cadenas E, Chance B. PMID: 7461143.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    243. Low level chemiluminescence of alveolar macrophages: spectral evidence for singlet oxygen generation. FEBS Lett. 1981 Jan 26; 123(2):225-8. Cadenas E, Daniele RP, Chance B. PMID: 7227515.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    244. Hydroperoxide-induced chemiluminescence of the perfused lung. Biochem J. 1980 Oct 15; 192(1):303-9. Cadenas E, Arad ID, Fisher AB, Boveris A, Chance B. PMID: 7305901; PMCID: PMC1162335.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    245. Chemiluminescence of lipid vesicles supplemented with cytochrome c and hydroperoxide. Biochem J. 1980 Jun 15; 188(3):577-83. Cadenas E, Boveris A, Chance B. PMID: 6258556; PMCID: PMC1161937.
      View in: PubMed   Mentions: 3     Fields:    
    246. Low level chemiluminescence of the cytochrome c-catalyzed decomposition of hydrogen peroxide. FEBS Lett. 1980 May 05; 113(2):141-4. Cadenas E, Varsavsky AI, Boveris A, Chance B. PMID: 6248357.
      View in: PubMed   Mentions: 3     Fields:    
    247. Enhancement of hydrogen peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria. Biochem J. 1980 Apr 15; 188(1):31-7. Cadenas E, Boveris A. PMID: 7406888; PMCID: PMC1162533.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    248. Spectral analysis of the low level chemiluminescence of H2O2-supplemented ferricytochrome c. FEBS Lett. 1980 Apr 07; 112(2):285-8. Cadenas E, Boveris A, Chance B. PMID: 6245934.
      View in: PubMed   Mentions:    Fields:    
    249. Low-level chemiluminescence of hydroperoxide-supplemented cytochrome c. Biochem J. 1980 Apr 01; 187(1):131-40. Cadenas E, Boveris A, Chance B. PMID: 6250533; PMCID: PMC1162500.
      View in: PubMed   Mentions: 10     Fields:    
    250. Low-level chemiluminescence of bovine heart submitochondrial particles. Biochem J. 1980 Mar 15; 186(3):659-67. Cadenas E, Boveris A, Chance B. PMID: 6249259; PMCID: PMC1161700.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    251. Partial spectral analysis of the hydroperoxide-induced chemiluminescence of the perfused lung. FEBS Lett. 1980 Mar 10; 111(2):413-8. Cadenas E, Arad ID, Boveris A, Fisher AB, Chance B. PMID: 7358183.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    252. Organ chemiluminescence: noninvasive assay for oxidative radical reactions. Proc Natl Acad Sci U S A. 1980 Jan; 77(1):347-51. Boveris A, Cadenas E, Reiter R, Filipkowski M, Nakase Y, Chance B. PMID: 6928628; PMCID: PMC348267.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    253. Synthesis of cytoplasmic membrane during growth and division of Escherichia coli. Dispersive behaviour of respiratory nitrate reductase. Biochem J. 1979 Oct 15; 184(1):45-50. Cadenas E, Garland PB. PMID: 393253; PMCID: PMC1161672.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    254. Low level chemiluminescence of intact polymorphonuclear leukocytes. FEBS Lett. 1979 Jun 01; 102(1):38-42. Kakinuma K, Cadenas E, Boveris A, Chance B. PMID: 378700.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    255. Nitrate Utilization by the Diatom Skeletonema costatum: I. Kinetics of Nitrate Uptake. Plant Physiol. 1978 Dec; 62(6):987-90. Serra JL, Llama MJ, Cadenas E. PMID: 16660652; PMCID: PMC1092268.
      View in: PubMed   Mentions: 12     Fields:    
    256. Nitrate Utilization by the Diatom Skeletonema costatum: II. Regulation of Nitrate Uptake. Plant Physiol. 1978 Dec; 62(6):991-4. Serra JL, Llama MJ, Cadenas E. PMID: 16660653; PMCID: PMC1092269.
      View in: PubMed   Mentions: 3     Fields:    
    257. Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch Biochem Biophys. 1977 Apr 30; 180(2):248-57. Cadenas E, Boveris A, Ragan CI, Stoppani AO. PMID: 195520.
      View in: PubMed   Mentions: 193     Fields:    Translation:AnimalsCells
    258. Role of ubiquinone in the mitochondrial generation of hydrogen peroxide. Biochem J. 1976 May 15; 156(2):435-44. Boveris A, Cadenas E, Stoppani AO. PMID: 182149; PMCID: PMC1163765.
      View in: PubMed   Mentions: 132     Fields:    Translation:AnimalsCells
    259. Mitochondrial production of superoxide anions and its relationship to the antimycin insensitive respiration. FEBS Lett. 1975 Jul 01; 54(3):311-4. Boveris A, Cadenas E. PMID: 236930.
      View in: PubMed   Mentions: 78     Fields:    Translation:AnimalsCells
    260. The ketokinase activity of the intestinal mucosa. Biochim Biophys Acta. 1960 Aug 26; 42:490-8. CADENAS E, SOLS A. PMID: 13689718.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
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