John P Walsh, PhD

Title(s)Associate Professor of Gerontology, Associate Dean of Education
SchoolSchool of Gerontology
AddressGER 228B
University Park Campus
Los Angeles CA 90089-0191
Phone+1 213 740 4908
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    John Walsh, Ph.D., is an Associate Professor of Gerontology and a member of the Neuroscience Program at USC. He received his undergraduate degree in biology from the University of California, Irvine, and was awarded a Ph.D. in physiology and biomedical sciences from the University of Texas School of Medicine in Houston. Dr. Walsh’s research focuses on the electrophysiological analysis of brain areas that are targets of age related disease. Studies on aging, calcium, and free radical physiology are performed in Dr. Walsh’s laboratory as they relate to changes in synaptic plasticity and cell behavior. His research also examines how toxic environmental challenges affect nerve cell populations typically lost in Parkinson’s disease, Huntington’s disease, and Alzheimer’s disease.

    The focus of my laboratory is to understand dopamine and glutamate synaptic physiology in the striatum under normal and pathological conditions. We use the analysis of short and long-term synaptic plasticity at corticostriatal synapes to study striatal pathology and rely upon, whole cell voltage clamp, intracellular and field potential recordings in the analysis. We also use fast-cyclic voltammetry to study dopamine physiology in the same brain slices. A parallel study is being performed in aged animals to describe how aging impacts synaptic integration and the mechanisms for any observed changes caused by the aging process.

    A second interest in the laboratory is to describe the modulation of synaptic function and key conductances in striatal neurons following the generation of reactive oxygen species (ROS) under conditions of hypoxia. Part of this NIH funded study uses the complex II inhibitor 3-nitropropionic acid (3-NP) to examine acute and long-term survival and the synaptic consequences of chemical hypoxia.

    We also have been studying the impact of MPTP treatment on striatal physiology in mice and squirel monkeys in collaboration with Drs. Mike Jakowec and Giselle Petzinger from USC’s Department of Neurology.

    These research interests are connected by the underlying hypotheses that aging and disease create shifts in ROS homeostasis, which possibly follow similar pathways in the striatum.”

    Dr. Walsh spends his free time surfing in southern Orange County.
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    Mitchondrial inhibition mimics corticostriatal aging
    NIH R01AG021937Aug 1, 2004 - Jul 31, 2010
    Role: Principal Investigator
    Glutamate-Dopamine Plasticity in Nigrostriatal Injury: Excerise Enhanced Recovery
    NIH R01NS044327Jun 1, 2002 - May 31, 2012
    Role: Co-Principal Investigator
    NIH R29AG012679Aug 10, 1995 - Dec 31, 2001
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis. Thyroid. 2024 Mar 28. Osinga JAJ, Liu Y, Männistö T, Vafeiadi M, Tao FB, Vaidya B, Vrijkotte TGM, Mosso L, Bassols J, López-Bermejo A, Boucai L, Aminorroaya A, Feldt-Rasmussen U, Hisada A, Yoshinaga J, Broeren MAC, Itoh S, Kishi R, Ashoor G, Chen L, Veltri F, Lu X, Taylor PN, Brown SJ, Chatzi L, Popova PV, Grineva EN, Ghafoor F, Pirzada A, Kianpour M, Oken E, Suvanto E, Hattersley A, Rebagliato M, Riaño-Galán I, Irizar A, Vrijheid M, Delgado-Saborit JM, Fernández-Somoano A, Santa-Marina L, Boelaert K, Brenta G, Dhillon-Smith R, Dosiou C, Eaton JL, Guan H, Lee SY, Maraka S, Morris-Wiseman LF, Nguyen CT, Shan Z, Guxens M, Pop VJM, Walsh JP, Nicolaides KH, D'Alton ME, Visser WE, Carty DM, Delles C, Nelson SM, Alexander EK, Chaker L, Palomaki GE, Peeters RP, Bliddal S, Huang K, Poppe KG, Pearce EN, Derakhshan A, Korevaar TIM. PMID: 38546971.
      View in: PubMed   Mentions:    Fields:    
    2. Epigenome-wide Association Study Shows Differential DNA Methylation of MDC1, KLF9, and CUTA in Autoimmune Thyroid Disease. J Clin Endocrinol Metab. 2024 Mar 15; 109(4):992-999. Lafontaine N, Shore CJ, Campbell PJ, Mullin BH, Brown SJ, Panicker V, Dudbridge F, Brix TH, Hegedüs L, Wilson SG, Bell JT, Walsh JP. PMID: 37962983; PMCID: PMC10940258.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget's disease of bone. Ann Rheum Dis. 2024 Mar 12; 83(4):529-536. Phillips J, Subedi D, Lewis SC, Keerie C, Cronin O, Porteous M, Moore D, Cetnarskyj R, Ranganath L, Selby PL, Turgut T, Hampson G, Chandra R, Ho S, Tobias J, Young-Min S, McKenna MJ, Crowley RK, Fraser WD, Tang JCY, Gennari L, Nuti R, Brandi ML, Del Pino-Montes J, Devogelaer JP, Durnez A, Isaia GC, Di Stefano M, Guanabens N, Blanch Rubio J, Seibel MJ, Walsh JP, Rea SL, Kotowicz MA, Nicholson GC, Duncan EL, Major G, Horne A, Gilchrist N, Ralston SH. PMID: 38123339; PMCID: PMC10958267.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Association of Gestational Free and Total Triiodothyronine With Gestational Hypertension, Preeclampsia, Preterm Birth, and Birth Weight: An Individual Participant Data Meta-analysis. J Clin Endocrinol Metab. 2024 Feb 20; 109(3):e1290-e1298. Derakhshan A, Männistö T, Chen L, Osinga JAJ, Ashoor G, Lu X, Bliddal S, Tao FB, Brown SJ, Vaidya B, Hattersley AT, Itoh S, Popova PV, Aminorroaya A, Kishi R, Kianpour M, Vasukova EA, López-Bermejo A, Oken E, Chatzi L, Vafeiadi M, Bramer WM, Bassols J, Lertxundi A, Fernández-Somoano A, Carrasco P, Auvinen J, Huang K, Feldt-Rasmussen U, Grineva EN, Alexander EK, Pearce EN, Chaker L, Walsh JP, Peeters RP, Guxens M, Suvanto E, Nicolaides KH, Korevaar TIM. PMID: 37878891; PMCID: PMC10876397.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. TSH and FT4 Reference Interval Recommendations and Prevalence of Gestational Thyroid Dysfunction: Quantification of Current Diagnostic Approaches. J Clin Endocrinol Metab. 2024 Feb 20; 109(3):868-878. Osinga JAJ, Derakhshan A, Feldt-Rasmussen U, Huang K, Vrijkotte TGM, Männistö T, Bassols J, López-Bermejo A, Aminorroaya A, Vafeiadi M, Broeren MAC, Palomaki GE, Ashoor G, Chen L, Lu X, Taylor PN, Tao FB, Brown SJ, Sitoris G, Chatzi L, Vaidya B, Popova PV, Vasukova EA, Kianpour M, Suvanto E, Grineva EN, Hattersley A, Pop VJM, Nelson SM, Walsh JP, Nicolaides KH, D'Alton ME, Poppe KG, Chaker L, Bliddal S, Korevaar TIM. PMID: 37740543; PMCID: PMC10876390.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Case Presentation: Functional Assessment of a CASR Variant Identified in a Patient with Hypercalcaemia Confirms Familial Hypocalciuric Hypercalcaemia in the Patient and a Sister Previously Misdiagnosed with Primary Hyperparathyroidism. Case Rep Endocrinol. 2024; 2024:6652801. Ward BK, Loffell KA, Walsh JP, Howe WD, Brown SJ, Wilson SG. PMID: 38343604; PMCID: PMC10858793.
      View in: PubMed   Mentions:
    7. Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications. Nat Commun. 2024 Jan 30; 15(1):888. Sterenborg RBTM, Steinbrenner I, Li Y, Bujnis MN, Naito T, Marouli E, Galesloot TE, Babajide O, Andreasen L, Astrup A, Åsvold BO, Bandinelli S, Beekman M, Beilby JP, Bork-Jensen J, Boutin T, Brody JA, Brown SJ, Brumpton B, Campbell PJ, Cappola AR, Ceresini G, Chaker L, Chasman DI, Concas MP, Coutinho de Almeida R, Cross SM, Cucca F, Deary IJ, Kjaergaard AD, Echouffo Tcheugui JB, Ellervik C, Eriksson JG, Ferrucci L, Freudenberg J, GHS DiscovEHR, Regeneron Genetics Center, Fuchsberger C, Gieger C, Giulianini F, Gögele M, Graham SE, Grarup N, Gunjaca I, Hansen T, Harding BN, Harris SE, Haunsø S, Hayward C, Hui J, Ittermann T, Jukema JW, Kajantie E, Kanters JK, Kårhus LL, Kiemeney LALM, Kloppenburg M, Kühnel B, Lahti J, Langenberg C, Lapauw B, Leese G, Li S, Liewald DCM, Linneberg A, Lominchar JVT, Luan J, Martin NG, Matana A, Meima ME, Meitinger T, Meulenbelt I, Mitchell BD, Møllehave LT, Mora S, Naitza S, Nauck M, Netea-Maier RT, Noordam R, Nursyifa C, Okada Y, Onano S, Papadopoulou A, Palmer CNA, Pattaro C, Pedersen O, Peters A, Pietzner M, Polašek O, Pramstaller PP, Psaty BM, Punda A, Ray D, Redmond P, Richards JB, Ridker PM, Russ TC, Ryan KA, Olesen MS, Schultheiss UT, Selvin E, Siddiqui MK, Sidore C, Slagboom PE, Sørensen TIA, Soto-Pedre E, Spector TD, Spedicati B, Srinivasan S, Starr JM, Stott DJ, Tanaka T, Torlak V, Trompet S, Tuhkanen J, Uitterlinden AG, van den Akker EB, van den Eynde T, van der Klauw MM, van Heemst D, Verroken C, Visser WE, Vojinovic D, Völzke H, Waldenberger M, Walsh JP, Wareham NJ, Weiss S, Willer CJ, Wilson SG, Wolffenbuttel BHR, Wouters HJCM, Wright MJ, Yang Q, Zemunik T, Zhou W, Zhu G, Zöllner S, Smit JWA, Peeters RP, Köttgen A, Teumer A, Medici M. PMID: 38291025; PMCID: PMC10828500.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Hyperthyroidism. Lancet. 2024 Feb 24; 403(10428):768-780. Chaker L, Cooper DS, Walsh JP, Peeters RP. PMID: 38278171.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Age-dependent genetic regulation of osteoarthritis: independent effects of immune system genes. Arthritis Res Ther. 2023 12 01; 25(1):232. Kenny J, Mullin BH, Tomlinson W, Robertson B, Yuan J, Chen W, Zhao J, Pavlos NJ, Walsh JP, Wilson SG, Tickner J, Morahan G, Xu J. PMID: 38041181; PMCID: PMC10691153.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    10. Leveraging osteoclast genetic regulatory data to identify genes with a role in osteoarthritis. Genetics. 2023 10 04; 225(2). Mullin BH, Zhu K, Brown SJ, Mullin S, Dudbridge F, Pavlos NJ, Richards JB, Grundberg E, Bell JT, Zeggini E, Walsh JP, Xu J, Wilson SG. PMID: 37579195; PMCID: PMC10550309.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. A case of catamenial erythema multiforme major successfully treated with goserelin. Endocrinol Diabetes Metab Case Rep. 2023 Oct 01; 2023(4). Tyack LT, Stuckey BGA, Walsh JP. PMID: 38006658; PMCID: PMC10762591.
      View in: PubMed   Mentions:
    12. The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis. Lancet Diabetes Endocrinol. 2023 10; 11(10):743-754. Xu Y, Derakhshan A, Hysaj O, Wildisen L, Ittermann T, Pingitore A, Abolhassani N, Medici M, Kiemeney LALM, Riksen NP, Dullaart RPF, Trompet S, Dörr M, Brown SJ, Schmidt B, Führer-Sakel D, Vanderpump MPJ, Muendlein A, Drexel H, Fink HA, Ikram MK, Kavousi M, Rhee CM, Bensenor IM, Azizi F, Hankey GJ, Iacoviello M, Imaizumi M, Ceresini G, Ferrucci L, Sgarbi JA, Bauer DC, Wareham N, Boelaert K, Bakker SJL, Jukema JW, Vaes B, Iervasi G, Yeap BB, Westendorp RGJ, Korevaar TIM, Völzke H, Razvi S, Gussekloo J, Walsh JP, Cappola AR, Rodondi N, Peeters RP, Chaker L, Thyroid Studies Collaboration. PMID: 37696273; PMCID: PMC10866328.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    13. Genetic determinants of thyroid function in children. Eur J Endocrinol. 2023 Aug 02; 189(2):164-174. Mulder TA, Campbell PJ, Taylor PN, Peeters RP, Wilson SG, Medici M, Dayan C, Jaddoe VVW, Walsh JP, Martin NG, Tiemeier H, Korevaar TIM. PMID: 37530217; PMCID: PMC10402705.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Three Cases of Non-islet Cell Tumor Hypoglycemia Highlighting Efficacy of Glucocorticoid Treatment. JCEM Case Rep. 2023 Jul; 1(4):luad045. Voon K, Simpson A, Fegan PG, Walsh JP. PMID: 37909001; PMCID: PMC10580471.
      View in: PubMed   Mentions:
    15. Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis. Commun Biol. 2023 07 04; 6(1):691. Medina-Gomez C, Mullin BH, Chesi A, Prijatelj V, Kemp JP, Shochat-Carvalho C, Trajanoska K, Wang C, Joro R, Evans TE, Schraut KE, Li-Gao R, Ahluwalia TS, Zillikens MC, Zhu K, Mook-Kanamori DO, Evans DS, Nethander M, Knol MJ, Thorleifsson G, Prokic I, Zemel B, Broer L, McGuigan FE, van Schoor NM, Reppe S, Pawlak MA, Ralston SH, van der Velde N, Lorentzon M, Stefansson K, Adams HHH, Wilson SG, Ikram MA, Walsh JP, Lakka TA, Gautvik KM, Wilson JF, Orwoll ES, van Duijn CM, Bønnelykke K, Uitterlinden AG, Styrkársdóttir U, Akesson KE, Spector TD, Tobias JH, Ohlsson C, Felix JF, Bisgaard H, Grant SFA, Richards JB, Evans DM, van der Eerden B, van de Peppel J, Ackert-Bicknell C, Karasik D, Kague E, Rivadeneira F. PMID: 37402774; PMCID: PMC10319806.
      View in: PubMed   Mentions: Translation:Animals
    16. Relationships between longitudinal changes in body composition and bone mineral density in middle-to-older aged Australians. Osteoporos Int. 2023 Sep; 34(9):1601-1611. Zhu K, Hunter M, James A, Lim EM, Walsh JP. PMID: 37233793; PMCID: PMC10427547.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Gastropulmonary fistula following sleeve gastrectomy: use of dual-energy CT following oral contrast administration to confirm diagnosis. Radiol Case Rep. 2023 May; 18(5):1895-1897. Boerkoel P, Abdellatif W, Walsh JP, Sugrue G, Louis LJ, Khosa F, Nicolaou S, Murray N. PMID: 36942006; PMCID: PMC10023850.
      View in: PubMed   Mentions:
    18. Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9. Thyroid. 2023 03; 33(3):301-311. Weihs A, Chaker L, Martin TC, Braun KVE, Campbell PJ, Cox SR, Fornage M, Gieger C, Grabe HJ, Grallert H, Harris SE, Kühnel B, Marioni RE, Martin NG, McCartney DL, McRae AF, Meisinger C, van Meurs JBJ, Nano J, Nauck M, Peters A, Prokisch H, Roden M, Selvin E, Beekman M, van Heemst D, Slagboom EP, Swenson BR, Tin A, Tsai PC, Uitterlinden A, Visser WE, Völzke H, Waldenberger M, Walsh JP, Köttgen A, Wilson SG, Peeters RP, Bell JT, Medici M, Teumer A. PMID: 36719767; PMCID: PMC10024591.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. DNA Methylation in Autoimmune Thyroid Disease. J Clin Endocrinol Metab. 2023 02 15; 108(3):604-613. Lafontaine N, Wilson SG, Walsh JP. PMID: 36420742.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    20. Shared genetics and causal relationships between migraine and thyroid function traits. Cephalalgia. 2023 02; 43(2):3331024221139253. Tasnim S, Wilson SG, Walsh JP, Nyholt DR, International Headache Genetics Consortium (IHGC). PMID: 36739509.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Cross-Trait Genetic Analyses Indicate Pleiotropy and Complex Causal Relationships between Headache and Thyroid Function Traits. Genes (Basel). 2022 12 21; 14(1). Tasnim S, Wilson SG, Walsh JP, Nyholt DR. PMID: 36672757; PMCID: PMC9858525.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Longitudinal Stability of Vitamin D Status and Its Association With Bone Mineral Density in Middle-aged Australians. J Endocr Soc. 2022 Dec 15; 7(2):bvac187. Zhu K, Hunter M, Hui J, Murray K, James A, Lim EM, Cooke BR, Walsh JP. PMID: 36578880; PMCID: PMC9780649.
      View in: PubMed   Mentions: 2  
    23. Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies. Eur J Endocrinol. 2022 Nov 01; 187(5):S35-S46. Alwan H, Villoz F, Feller M, Dullaart RPF, Bakker SJL, Peeters RP, Kavousi M, Bauer DC, Cappola AR, Yeap BB, Walsh JP, Brown SJ, Ceresini G, Ferrucci L, Gussekloo J, Trompet S, Iacoviello M, Moon JH, Razvi S, Bensenor IM, Azizi F, Amouzegar A, Valdés S, Colomo N, Wareham NJ, Jukema JW, Westendorp RGJ, Kim KW, Rodondi N, Del Giovane C. PMID: 36070417; PMCID: PMC7613845.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis. J Clin Endocrinol Metab. 2022 09 28; 107(10):2925-2933. Osinga JAJ, Derakhshan A, Palomaki GE, Ashoor G, Männistö T, Maraka S, Chen L, Bliddal S, Lu X, Taylor PN, Vrijkotte TGM, Tao FB, Brown SJ, Ghafoor F, Poppe K, Veltri F, Chatzi L, Vaidya B, Broeren MAC, Shields BM, Itoh S, Mosso L, Popova PV, Anopova AD, Kishi R, Aminorroaya A, Kianpour M, López-Bermejo A, Oken E, Pirzada A, Vafeiadi M, Bramer WM, Suvanto E, Yoshinaga J, Huang K, Bassols J, Boucai L, Feldt-Rasmussen U, Grineva EN, Pearce EN, Alexander EK, Pop VJM, Nelson SM, Walsh JP, Peeters RP, Chaker L, Nicolaides KH, D'Alton ME, Korevaar TIM. PMID: 35861700; PMCID: PMC9516198.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    25. Association of Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies with Thyroid Function in Pregnancy: An Individual Participant Data Meta-Analysis. Thyroid. 2022 07; 32(7):828-840. Bliddal S, Derakhshan A, Xiao Y, Chen LM, Männistö T, Ashoor G, Tao F, Brown SJ, Vafeiadi M, Itoh S, Grineva EN, Taylor P, Ghafoor F, Vaidya B, Hattersley A, Mosso L, Oken E, Kishi R, Alexander EK, Maraka S, Huang K, Chaker L, Bassols J, Pirzada A, López-Bermejo A, Boucai L, Peeters RP, Pearce EN, Nelson SM, Chatzi L, Vrijkotte TG, Popova PV, Walsh JP, Nicolaides KH, Suvanto E, Lu X, Pop VJM, Forman JL, Korevaar TIM, Feldt-Rasmussen U. PMID: 35596568.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    26. Establishing a Total Hip T-Score Threshold to Measure Contralateral Hip Bone Mineral Density: Avoiding Missed Diagnosis of Osteoporosis. J Clin Densitom. 2022 Oct-Dec; 25(4):577-586. Zhu K, Hunter M, Stuckey BGA, Walsh JP. PMID: 35606279.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Thyroid Function across the Lifespan: Do Age-Related Changes Matter? Endocrinol Metab (Seoul). 2022 04; 37(2):208-219. Walsh JP. PMID: 35417936; PMCID: PMC9081302.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    28. Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes Endocrinol. 2022 04; 10(4):243-252. Toloza FJK, Derakhshan A, Männistö T, Bliddal S, Popova PV, Carty DM, Chen L, Taylor P, Mosso L, Oken E, Suvanto E, Itoh S, Kishi R, Bassols J, Auvinen J, López-Bermejo A, Brown SJ, Boucai L, Hisada A, Yoshinaga J, Shilova E, Grineva EN, Vrijkotte TGM, Sunyer J, Jiménez-Zabala A, Riaño-Galan I, Lopez-Espinosa MJ, Prokop LJ, Singh Ospina N, Brito JP, Rodriguez-Gutierrez R, Alexander EK, Chaker L, Pearce EN, Peeters RP, Feldt-Rasmussen U, Guxens M, Chatzi L, Delles C, Roeters van Lennep JE, Pop VJM, Lu X, Walsh JP, Nelson SM, Korevaar TIM, Maraka S. PMID: 35255260; PMCID: PMC10314731.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    29. Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies. Front Psychiatry. 2022; 13:774251. Syrogiannouli L, Wildisen L, Meuwese C, Bauer DC, Cappola AR, Gussekloo J, den Elzen WPJ, Trompet S, Westendorp RGJ, Jukema JW, Ferrucci L, Ceresini G, Åsvold BO, Chaker L, Peeters RP, Imaizumi M, Ohishi W, Vaes B, Völzke H, Sgarbi JA, Walsh JP, Dullaart RPF, Bakker SJL, Iacoviello M, Rodondi N, Del Giovane C. PMID: 35273528; PMCID: PMC8902696.
      View in: PubMed   Mentions:
    30. Functional Assessment of Calcium-Sensing Receptor Variants Confirms Familial Hypocalciuric Hypercalcemia. J Endocr Soc. 2022 May 01; 6(5):bvac025. Mullin BH, Pavlos NJ, Brown SJ, Walsh JP, McKellar RA, Wilson SG, Ward BK. PMID: 35356007; PMCID: PMC8962451.
      View in: PubMed   Mentions: 2  
    31. Imaging of Hockey-related Injuries of the Head, Neck, and Body. Semin Musculoskelet Radiol. 2022 Feb; 26(1):28-40. Holmes RD, Walsh JP, Yan YY, Mallinson PI, Andrews GT, Munk PL, Ouellette HA. PMID: 35139557.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Prospective Associations of Sugar-Sweetened Beverage Consumption During Adolescence with Body Composition and Bone Mass at Early Adulthood. J Nutr. 2022 02 08; 152(2):399-407. Bennett AM, Murray K, Ambrosini GL, Oddy WH, Walsh JP, Zhu K. PMID: 34791346; PMCID: PMC8826835.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. DXA-Derived vs Standard Anthropometric Measures for Predicting Cardiometabolic Risk in Middle-Aged Australian Men and Women. J Clin Densitom. 2022 Jul-Sep; 25(3):299-307. Zhu K, Walsh JP, Murray K, Hunter M, Hui J, Hung J. PMID: 35177350.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Investigating Potential Dose-Response Relationships between Vitamin D Status and Cognitive Performance: A Cross-Sectional Analysis in Middle- to Older-Aged Adults in the Busselton Healthy Ageing Study. Int J Environ Res Public Health. 2021 12 31; 19(1). Harse JD, Zhu K, Bucks RS, Hunter M, Lim EM, Cooke BR, Walsh JP, Murray K. PMID: 35010710; PMCID: PMC8744852.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function. PLoS One. 2021; 16(11):e0259556. Sultana MA, Cluning C, Kwong WS, Polain N, Pavlos NJ, Ratajczak T, Walsh JP, Xu J, Rea SL. PMID: 34735553; PMCID: PMC8568271.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    36. Genome-wide analysis of thyroid function in Australian adolescents highlights SERPINA7 and NCOA3. Eur J Endocrinol. 2021 Oct 11; 185(5):743-753. Nolan J, Campbell PJ, Brown SJ, Zhu G, Gordon S, Lim EM, Joseph J, Cross SM, Panicker V, Medland SE, Melton PE, Beilin LJ, Mori TA, Mullin BH, Pennell CE, Wang CA, Dudbridge F, Walsh JP, Martin NG, Wilson SG. PMID: 34524976.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. Prevalence and patterns of multimorbidity in Australian baby boomers: the Busselton healthy ageing study. BMC Public Health. 2021 08 11; 21(1):1539. Hunter ML, Knuiman MW, Musk BAW, Hui J, Murray K, Beilby JP, Hillman DR, Hung J, Newton RU, Bucks RS, Straker L, Walsh JP, Zhu K, Bruce DG, Eikelboom RH, Davis TME, Mackey DA, James AL. PMID: 34380465; PMCID: PMC8359115.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. A Single-Center 10-Year Retrospective Analysis of Cryoablation for the Management of Desmoid Tumors. J Vasc Interv Radiol. 2021 09; 32(9):1277-1287. Yan YY, Walsh JP, Munk PL, Mallinson PI, Simmons C, Clarkson PW, Jayaram PR, Heran MKS, Ouellette HA. PMID: 34089889.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    39. Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With KLF9 and DOT1L. J Clin Endocrinol Metab. 2021 04 23; 106(5):e2191-e2202. Lafontaine N, Campbell PJ, Castillo-Fernandez JE, Mullin S, Lim EM, Kendrew P, Lewer M, Brown SJ, Huang RC, Melton PE, Mori TA, Beilin LJ, Dudbridge F, Spector TD, Wright MJ, Martin NG, McRae AF, Panicker V, Zhu G, Walsh JP, Bell JT, Wilson SG. PMID: 33484127; PMCID: PMC8063248.
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    40. Familial Dysalbuminemic Hyperthyroxinemia as a Cause for Discordant Thyroid Function Tests. J Endocr Soc. 2021 Apr 01; 5(4):bvab012. Ting MJM, Zhang R, Lim EM, Ward BK, Wilson SG, Walsh JP. PMID: 33728390; PMCID: PMC7940171.
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    42. Molecular Mechanisms Lead to Sex-Specific COVID-19 Prognosis and Targeted Therapies. Front Med (Lausanne). 2020; 7:589060. Galbadage T, Peterson BM, Wang JS, Jayasekara A, Ramirez DA, Awada J, Walsh JP, Gunasekera RS. PMID: 33364247; PMCID: PMC7753152.
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    44. Relationship between visceral adipose tissue and bone mineral density in Australian baby boomers. Osteoporos Int. 2020 Dec; 31(12):2439-2448. Zhu K, Hunter M, James A, Lim EM, Cooke BR, Walsh JP. PMID: 32719992.
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    45. Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia. Calcif Tissue Int. 2020 09; 107(3):230-239. Magno AL, Leatherbarrow KM, Brown SJ, Wilson SG, Walsh JP, Ward BK. PMID: 32638038.
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    46. RSNA Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19: Interobserver Agreement Between Chest Radiologists. Can Assoc Radiol J. 2021 Feb; 72(1):159-166. Byrne D, Neill SBO, Müller NL, Müller CIS, Walsh JP, Jalal S, Parker W, Bilawich AM, Nicolaou S. PMID: 32615802; PMCID: PMC7335944.
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    48. Virtual monochromatic reconstructions of dual energy CT in abdominal trauma: optimization of energy level improves pancreas laceration conspicuity and diagnostic confidence. Emerg Radiol. 2021 Feb; 28(1):1-7. Sugrue G, Walsh JP, Zhang Y, Niu B, Macri F, Khasanova E, Metwally O, Murray N, Nicolaou S. PMID: 32474732.
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    49. Changes in Thyroid Function Across Adolescence: A Longitudinal Study. J Clin Endocrinol Metab. 2020 04 01; 105(4). Campbell PJ, Brown SJ, Kendrew P, Lewer M, Lim EM, Joseph J, Cross SM, Wright MJ, Martin NG, Wilson SG, Walsh JP. PMID: 31922575.
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    50. Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts. Genome Biol. 2020 03 26; 21(1):80. Mullin BH, Tickner J, Zhu K, Kenny J, Mullin S, Brown SJ, Dudbridge F, Pavlos NJ, Mocarski ES, Walsh JP, Xu J, Wilson SG. PMID: 32216834; PMCID: PMC7098081.
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    51. CT Imaging of Acute Ischemic Stroke [Formula: see text]. Can Assoc Radiol J. 2020 Aug; 71(3):266-280. Byrne D, Walsh JP, Sugrue G, Nicolaou S, Rohr A. PMID: 32157894.
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    52. Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases. Mol Cell Proteomics. 2020 05; 19(5):774-792. Martin TC, Šimurina M, Zabczynska M, Martinic Kavur M, Rydlewska M, Pezer M, Kozlowska K, Burri A, Vilaj M, Turek-Jabrocka R, Krnjajic-Tadijanovic M, Trofimiuk-Müldner M, Ugrina I, Litynska A, Hubalewska-Dydejczyk A, Trbojevic-Akmacic I, Lim EM, Walsh JP, Pochec E, Spector TD, Wilson SG, Lauc G. PMID: 32024769; PMCID: PMC7196582.
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    53. Prediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal Sinus. AJNR Am J Neuroradiol. 2020 01; 41(1):64-70. Byrne D, Walsh JP, Schmiedeskamp H, Settecase F, Heran MKS, Niu B, Salmeen AK, Rohr B, Field TS, Murray N, Rohr A. PMID: 31896566; PMCID: PMC6975329.
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    54. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis. JAMA. 2019 08 20; 322(7):632-641. Consortium on Thyroid and Pregnancy—Study Group on Preterm Birth, Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Carty DM, Meems M, Vaidya B, Shields B, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan C, Boucai L, Vafeiadi M, Grineva EN, Tkachuck AS, Pop VJM, Vrijkotte TG, Guxens M, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Murcia M, Lu X, Mukhtar S, Delles C, Feldt-Rasmussen U, Nelson SM, Alexander EK, Chaker L, Männistö T, Walsh JP, Pearce EN, Steegers EAP, Peeters RP. PMID: 31429897; PMCID: PMC6704759.
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    55. Physiological aging at striatal synapses. J Neurosci Res. 2019 12; 97(12):1720-1727. Walsh JP, Akopian G. PMID: 31237011.
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    56. Low thyroid function is not associated with an accelerated deterioration in renal function. Nephrol Dial Transplant. 2019 04 01; 34(4):650-659. Meuwese CL, van Diepen M, Cappola AR, Sarnak MJ, Shlipak MG, Bauer DC, Fried LP, Iacoviello M, Vaes B, Degryse J, Khaw KT, Luben RN, Åsvold BO, Bjøro T, Vatten LJ, de Craen AJM, Trompet S, Iervasi G, Molinaro S, Ceresini G, Ferrucci L, Dullaart RPF, Bakker SJL, Jukema JW, Kearney PM, Stott DJ, Peeters RP, Franco OH, Völzke H, Walsh JP, Bremner A, Sgarbi JA, Maciel RMB, Imaizumi M, Ohishi W, Dekker FW, Rodondi N, Gussekloo J, den Elzen WPJ, Thyroid Studies Collaboration. PMID: 29684213; PMCID: PMC6452200.
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    57. Lower serum 25-hydroxyvitamin D is associated with colorectal and breast cancer, but not overall cancer risk: a 20-year cohort study. Nutr Res. 2019 07; 67:100-107. Zhu K, Knuiman M, Divitini M, Hung J, Lim EM, Cooke BR, Walsh JP. PMID: 30982554.
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    58. Targeted sequencing of DCSTAMP in familial Paget's disease of bone. Bone Rep. 2019 Jun; 10:100198. Sultana MA, Pavlos NJ, Ward L, Walsh JP, Rea SL. PMID: 30886882; PMCID: PMC6403439.
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    60. Low 25-Hydroxyvitamin D Concentration Is Not Associated With Refractive Error in Middle-Aged and Older Western Australian Adults. Transl Vis Sci Technol. 2019 Jan; 8(1):13. Lingham G, Yazar S, Lucas RM, Walsh JP, Zhu K, Hunter M, Lim EM, Cooke BR, Mackey DA. PMID: 30697464; PMCID: PMC6348994.
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    61. Relationship Between Vitamin D Status From Childhood to Early Adulthood With Body Composition in Young Australian Adults. J Endocr Soc. 2019 Mar 01; 3(3):563-576. Zhu K, Oddy WH, Holt P, Ping-Delfos WCS, McVeigh J, Straker L, Mori TA, Lye S, Pennell C, Walsh JP. PMID: 30805568; PMCID: PMC6382407.
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    64. High-sensitivity cardiac troponin I and risk of incident atrial fibrillation hospitalisation in an Australian community-based cohort: The Busselton health study. Clin Biochem. 2018 Aug; 58:20-25. Zhu K, Hung J, Divitini M, Murray K, Lim EM, St John A, Walsh JP, Knuiman M. PMID: 29746826.
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    66. Arthroscopic Treatment of Iliopsoas Snapping in Patients With Radiographic Acetabular Dysplasia Using Iliopsoas Fractional Lengthening and Capsular Plication. Arthroscopy. 2018 06; 34(6):1841-1850. Hartigan DE, Perets I, Close MR, Walsh JP, Chaharbakhshi EO, Mohr MR, Domb BG. PMID: 29653792.
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    67. Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts. J Bone Miner Res. 2018 06; 33(6):1044-1051. Mullin BH, Zhu K, Xu J, Brown SJ, Mullin S, Tickner J, Pavlos NJ, Dudbridge F, Walsh JP, Wilson SG. PMID: 29473973.
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    68. Vitamin D and respiratory health in the Busselton Healthy Ageing Study. Respirology. 2018 Jun; 23(6):576-582. Mulrennan S, Knuiman M, Walsh JP, Hui J, Hunter M, Divitini M, Zhu K, Cooke BR, Musk AWB, James A. PMID: 29365367.
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    69. Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects. Am J Hum Genet. 2018 01 04; 102(1):88-102. Medina-Gomez C, Kemp JP, Trajanoska K, Luan J, Chesi A, Ahluwalia TS, Mook-Kanamori DO, Ham A, Hartwig FP, Evans DS, Joro R, Nedeljkovic I, Zheng HF, Zhu K, Atalay M, Liu CT, Nethander M, Broer L, Porleifsson G, Mullin BH, Handelman SK, Nalls MA, Jessen LE, Heppe DHM, Richards JB, Wang C, Chawes B, Schraut KE, Amin N, Wareham N, Karasik D, Van der Velde N, Ikram MA, Zemel BS, Zhou Y, Carlsson CJ, Liu Y, McGuigan FE, Boer CG, Bønnelykke K, Ralston SH, Robbins JA, Walsh JP, Zillikens MC, Langenberg C, Li-Gao R, Williams FMK, Harris TB, Akesson K, Jackson RD, Sigurdsson G, den Heijer M, van der Eerden BCJ, van de Peppel J, Spector TD, Pennell C, Horta BL, Felix JF, Zhao JH, Wilson SG, de Mutsert R, Bisgaard H, Styrkársdóttir U, Jaddoe VW, Orwoll E, Lakka TA, Scott R, Grant SFA, Lorentzon M, van Duijn CM, Wilson JF, Stefansson K, Psaty BM, Kiel DP, Ohlsson C, Ntzani E, van Wijnen AJ, Forgetta V, Ghanbari M, Logan JG, Williams GR, Bassett JHD, Croucher PI, Evangelou E, Uitterlinden AG, Ackert-Bicknell CL, Tobias JH, Evans DM, Rivadeneira F. PMID: 29304378; PMCID: PMC5777980.
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    70. Hip Arthroscopic Surgery With Labral Preservation and Capsular Plication in Patients With Borderline Hip Dysplasia: Minimum 5-Year Patient-Reported Outcomes. Am J Sports Med. 2018 02; 46(2):305-313. Domb BG, Chaharbakhshi EO, Perets I, Yuen LC, Walsh JP, Ashberg L. PMID: 29268026.
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    71. Clinical guidance for radioiodine refractory differentiated thyroid cancer. Clin Endocrinol (Oxf). 2018 04; 88(4):529-537. Gild ML, Topliss DJ, Learoyd D, Parnis F, Tie J, Hughes B, Walsh JP, McLeod DSA, Clifton-Bligh RJ, Robinson BG. PMID: 29095527.
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    72. Rationalizing Thyroid Function Testing: Which TSH Cutoffs Are Optimal for Testing Free T4? J Clin Endocrinol Metab. 2017 11 01; 102(11):4235-4241. Henze M, Brown SJ, Hadlow NC, Walsh JP. PMID: 28938415.
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    73. High-sensitivity cardiac troponin I and risk of cardiovascular disease in an Australianpopulation-based cohort. Heart. 2018 06; 104(11):895-903. Zhu K, Knuiman M, Divitini M, Murray K, Lim EM, St John A, Walsh JP, Hung J. PMID: 29066610.
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    74. Thyroid Function Within the Normal Range, Subclinical Hypothyroidism, and the Risk of Atrial Fibrillation. Circulation. 2017 Nov 28; 136(22):2100-2116. Baumgartner C, da Costa BR, Collet TH, Feller M, Floriani C, Bauer DC, Cappola AR, Heckbert SR, Ceresini G, Gussekloo J, den Elzen WPJ, Peeters RP, Luben R, Völzke H, Dörr M, Walsh JP, Bremner A, Iacoviello M, Macfarlane P, Heeringa J, Stott DJ, Westendorp RGJ, Khaw KT, Magnani JW, Aujesky D, Rodondi N, Thyroid Studies Collaboration. PMID: 29061566; PMCID: PMC5705446.
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    75. Serum 25-hydroxyvitamin D as a predictor of mortality and cardiovascular events: A 20-year study of a community-based cohort. Clin Endocrinol (Oxf). 2018 Jan; 88(1):154-163. Zhu K, Knuiman M, Divitini M, Hung J, Lim EM, Cooke BR, Walsh JP. PMID: 28949411.
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    76. The Changing Presentation of Paget's Disease of Bone in Australia, A High Prevalence Region. Calcif Tissue Int. 2017 12; 101(6):564-569. Britton C, Brown S, Ward L, Rea SL, Ratajczak T, Walsh JP. PMID: 28884211.
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    77. Thyroid Function Tests in the Reference Range and Fracture: Individual Participant Analysis of Prospective Cohorts. J Clin Endocrinol Metab. 2017 08 01; 102(8):2719-2728. Aubert CE, Floriani C, Bauer DC, da Costa BR, Segna D, Blum MR, Collet TH, Fink HA, Cappola AR, Syrogiannouli L, Peeters RP, Åsvold BO, den Elzen WPJ, Luben RN, Bremner AP, Gogakos A, Eastell R, Kearney PM, Hoff M, Le Blanc E, Ceresini G, Rivadeneira F, Uitterlinden AG, Khaw KT, Langhammer A, Stott DJ, Westendorp RGJ, Ferrucci L, Williams GR, Gussekloo J, Walsh JP, Aujesky D, Rodondi N, Thyroid Studies Collaboration. PMID: 28482002; PMCID: PMC6283437.
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    78. Single nucleotide polymorphism 1623 A/G (rs180195) in the promoter of the Thyroglobulin gene is associated with autoimmune thyroid disease but not with thyroid ophthalmopathy. Clin Ophthalmol. 2017; 11:1337-1345. Lahooti H, Edirimanne S, Walsh JP, Delbridge L, Hibbert EJ, Wall JR. PMID: 28794611; PMCID: PMC5536092.
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    80. Tracking of vitamin D status from childhood to early adulthood and its association with peak bone mass. Am J Clin Nutr. 2017 Jul; 106(1):276-283. Zhu K, Oddy WH, Holt P, Ping-Delfos WCS, Mountain J, Lye S, Pennell C, Hart PH, Walsh JP. PMID: 28592609.
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    81. Depressive symptoms, body composition and bone mass in young adults: a prospective cohort study. Int J Obes (Lond). 2017 04; 41(4):576-581. Zhu K, Allen K, Mountain J, Lye S, Pennell C, Walsh JP. PMID: 27881857.
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    82. Pooled genome wide association detects association upstream of FCRL3 with Graves' disease. BMC Genomics. 2016 11 18; 17(1):939. Khong JJ, Burdon KP, Lu Y, Laurie K, Leonardos L, Baird PN, Sahebjada S, Walsh JP, Gajdatsy A, Ebeling PR, Hamblin PS, Wong R, Forehan SP, Fourlanos S, Roberts AP, Doogue M, Selva D, Montgomery GW, Macgregor S, Craig JE. PMID: 27863461; PMCID: PMC5116198.
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    83. Thyroid Function Within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis. J Clin Endocrinol Metab. 2016 11; 101(11):4270-4282. Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci L, Maciel RM, Westendorp RG, Jukema JW, Ceresini G, Imaizumi M, Hofman A, Bakker SJ, Franklyn JA, Khaw KT, Bauer DC, Walsh JP, Razvi S, Gussekloo J, Völzke H, Franco OH, Cappola AR, Rodondi N, Peeters RP, Thyroid Studies Collaboration. PMID: 27603906; PMCID: PMC5095234.
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    84. HABP2 germline variants are uncommon in familial nonmedullary thyroid cancer. BMC Med Genet. 2016 08 17; 17(1):60. Weeks AL, Wilson SG, Ward L, Goldblatt J, Hui J, Walsh JP. PMID: 27530615; PMCID: PMC4988026.
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    85. Managing thyroid disease in general practice. Med J Aust. 2016 Aug 15; 205(4):179-84. Walsh JP. PMID: 27510349.
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    91. Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density. BMC Genomics. 2016 Feb 25; 17:136. Mullin BH, Walsh JP, Zheng HF, Brown SJ, Surdulescu GL, Curtis C, Breen G, Dudbridge F, Richards JB, Spector TD, Wilson SG. PMID: 26911590; PMCID: PMC4766752.
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    92. Mechanisms underlying the benefits of anticonvulsants over lithium in the treatment of bipolar disorder. Neuroreport. 2016 Feb 10; 27(3):131-5. Corrado AC, Walsh JP. PMID: 26702549.
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    95. Novel single-nucleotide polymorphisms in the calsequestrin-1 gene are associated with Graves' ophthalmopathy and Hashimoto's thyroiditis. Clin Ophthalmol. 2015; 9:1731-40. Lahooti H, Cultrone D, Edirimanne S, Walsh JP, Delbridge L, Cregan P, Champion B, Wall JR. PMID: 26445519; PMCID: PMC4590686.
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    106. Gender differences in the relationships between lean body mass, fat mass and peak bone mass in young adults. Osteoporos Int. 2014 May; 25(5):1563-70. Zhu K, Briffa K, Smith A, Mountain J, Briggs AM, Lye S, Pennell C, Straker L, Walsh JP. PMID: 24647886.
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    108. Treadmill exercise reverses dendritic spine loss in direct and indirect striatal medium spiny neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease. Neurobiol Dis. 2014 Mar; 63:201-9. Toy WA, Petzinger GM, Leyshon BJ, Akopian GK, Walsh JP, Hoffman MV, Vuckovic MG, Jakowec MW. PMID: 24316165; PMCID: PMC3940446.
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    117. Age-specific TSH reference ranges have minimal impact on the diagnosis of thyroid dysfunction. Clin Endocrinol (Oxf). 2012 Nov; 77(5):773-9. Kahapola-Arachchige KM, Hadlow N, Wardrop R, Lim EM, Walsh JP. PMID: 22703566.
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    128. Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Nat Genet. 2011 May 29; 43(7):685-9. Albagha OM, Wani SE, Visconti MR, Alonso N, Goodman K, Brandi ML, Cundy T, Chung PY, Dargie R, Devogelaer JP, Falchetti A, Fraser WD, Gennari L, Gianfrancesco F, Hooper MJ, Van Hul W, Isaia G, Nicholson GC, Nuti R, Papapoulos S, Montes Jdel P, Ratajczak T, Rea SL, Rendina D, Gonzalez-Sarmiento R, Di Stefano M, Ward LC, Walsh JP, Ralston SH, Genetic Determinants of Paget's Disease (GDPD) Consortium. PMID: 21623375.
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    145. Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding. J Bone Miner Res. 2009 Jul; 24(7):1216-23. Rea SL, Walsh JP, Ward L, Magno AL, Ward BK, Shaw B, Layfield R, Kent GN, Xu J, Ratajczak T. PMID: 19257822.
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    146. Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia. J Neurosci. 2008 Sep 17; 28(38):9585-97. Akopian G, Crawford C, Beal MF, Cappelletti M, Jakowec MW, Petzinger GM, Zheng L, Gheorghe SL, Reichel CM, Chow R, Walsh JP. PMID: 18799690; PMCID: PMC2724653.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    147. Assessment of thyroid function during pregnancy: first-trimester (weeks 9-13) reference intervals derived from Western Australian women. Med J Aust. 2008 Sep 01; 189(5):250-3. Gilbert RM, Hadlow NC, Walsh JP, Fletcher SJ, Brown SJ, Stuckey BG, Lim EM. PMID: 18759718.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    148. Genetic loci linked to pituitary-thyroid axis set points: a genome-wide scan of a large twin cohort. J Clin Endocrinol Metab. 2008 Sep; 93(9):3519-23. Panicker V, Wilson SG, Spector TD, Brown SJ, Kato BS, Reed PW, Falchi M, Richards JB, Surdulescu GL, Lim EM, Fletcher SJ, Walsh JP. PMID: 18611976.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    149. Online multimedia teaching tool for Parkinson's disease. J Undergrad Neurosci Educ. 2008; 6(2):A68-73. Misiaszek G, Riconscente M, Henke M, Walsh JP. PMID: 23493487; PMCID: PMC3592663.
      View in: PubMed   Mentions: 4  
    150. Significant inverse relationship between serum free T4 concentration and body mass index in euthyroid subjects: differences between smokers and nonsmokers. Clin Endocrinol (Oxf). 2008 Oct; 69(4):648-52. Makepeace AE, Bremner AP, O'Leary P, Leedman PJ, Feddema P, Michelangeli V, Walsh JP. PMID: 18346211.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    151. Treatment of Paget's disease of bone: a survey of clinical practice in Australia. Bone. 2008 Jun; 42(6):1219-25. Walsh JP, Attewell R, Stuckey BG, Hooper MJ, Wark JD, Fletcher S, Ferrari V, Eisman JA. PMID: 18353737.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    152. Heritability of serum TSH, free T4 and free T3 concentrations: a study of a large UK twin cohort. Clin Endocrinol (Oxf). 2008 Apr; 68(4):652-9. Panicker V, Wilson SG, Spector TD, Brown SJ, Falchi M, Richards JB, Surdulescu GL, Lim EM, Fletcher SJ, Walsh JP. PMID: 17970774.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    153. Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury. J Neurosci. 2007 May 16; 27(20):5291-300. Petzinger GM, Walsh JP, Akopian G, Hogg E, Abernathy A, Arevalo P, Turnquist P, Vuckovic M, Fisher BE, Togasaki DM, Jakowec MW. PMID: 17507552; PMCID: PMC6672356.
      View in: PubMed   Mentions: 133     Fields:    Translation:AnimalsCells
    154. Differences between endocrinologists and endocrine surgeons in management of the solitary thyroid nodule. Clin Endocrinol (Oxf). 2007 Jun; 66(6):844-53. Walsh JP, Ryan SA, Lisewski D, Alhamoudi MZ, Brown S, Bennedbaek FN, Hegedüs L. PMID: 17437521.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    155. Reliable long-lasting depression interacts with variable short-term facilitation to determine corticostriatal paired-pulse plasticity in young rats. J Physiol. 2007 Apr 01; 580(Pt 1):225-40. Akopian G, Walsh JP. PMID: 17234703; PMCID: PMC2075419.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    156. Subclinical thyroid dysfunction and blood pressure: a community-based study. Clin Endocrinol (Oxf). 2006 Oct; 65(4):486-91. Walsh JP, Bremner AP, Bulsara MK, O'Leary P, Leedman PJ, Feddema P, Michelangeli V. PMID: 16984241.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    157. Erectile dysfunction predicts generalised cardiovascular disease: evidence from a case-control study. Atherosclerosis. 2007 Oct; 194(2):458-64. Stuckey BG, Walsh JP, Ching HL, Stuckey AW, Palmer NR, Thompson PL, Watts GF. PMID: 16989839.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    158. Urine free cortisol analysis by automated immunoassay and high-performance liquid chromatography for the investigation of Cushing's syndrome. Ann Clin Biochem. 2006 Sep; 43(Pt 5):402-7. Ching SY, Lim EM, Beilby J, Bhagat C, Rossi E, Walsh JP, Pullan P. PMID: 17022883.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    159. Pre- and postsynaptic contributions to age-related alterations in corticostriatal synaptic plasticity. Synapse. 2006 Sep 01; 60(3):223-38. Akopian G, Walsh JP. PMID: 16739119.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    160. A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype. J Bone Miner Res. 2006 Jul; 21(7):1136-45. Rea SL, Walsh JP, Ward L, Yip K, Ward BK, Kent GN, Steer JH, Xu J, Ratajczak T. PMID: 16813535.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    161. Small changes in thyroxine dosage do not produce measurable changes in hypothyroid symptoms, well-being, or quality of life: results of a double-blind, randomized clinical trial. J Clin Endocrinol Metab. 2006 Jul; 91(7):2624-30. Walsh JP, Ward LC, Burke V, Bhagat CI, Shiels L, Henley D, Gillett MJ, Gilbert R, Tanner M, Stuckey BG. PMID: 16670161.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    162. Novel mutations in the calcium-sensing receptor gene associated with biochemical and functional differences in familial hypocalciuric hypercalcaemia. Clin Endocrinol (Oxf). 2006 May; 64(5):580-7. Ward BK, Magno AL, Blitvich BJ, Rea AJ, Stuckey BG, Walsh JP, Ratajczak T. PMID: 16649980.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    163. Investigations of thyroid hormones and antibodies based on a community health survey: the Busselton thyroid study. Clin Endocrinol (Oxf). 2006 Jan; 64(1):97-104. O'Leary PC, Feddema PH, Michelangeli VP, Leedman PJ, Chew GT, Knuiman M, Kaye J, Walsh JP. PMID: 16402936.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    164. Thyroid dysfunction and serum lipids: a community-based study. Clin Endocrinol (Oxf). 2005 Dec; 63(6):670-5. Walsh JP, Bremner AP, Bulsara MK, O'leary P, Leedman PJ, Feddema P, Michelangeli V. PMID: 16343102.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    165. Subclinical thyroid dysfunction as a risk factor for cardiovascular disease. Arch Intern Med. 2005 Nov 28; 165(21):2467-72. Walsh JP, Bremner AP, Bulsara MK, O'Leary P, Leedman PJ, Feddema P, Michelangeli V. PMID: 16314542.
      View in: PubMed   Mentions: 131     Fields:    Translation:Humans
    166. Parity and the risk of autoimmune thyroid disease: a community-based study. J Clin Endocrinol Metab. 2005 Sep; 90(9):5309-12. Walsh JP, Bremner AP, Bulsara MK, O'Leary P, Leedman PJ, Feddema P, Michelangeli V. PMID: 15956077.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    167. Increased susceptibility of glutathione peroxidase-1 transgenic mice to kainic acid-related seizure activity and hippocampal neuronal cell death. Exp Neurol. 2005 Mar; 192(1):203-14. Boonplueang R, Akopian G, Stevenson FF, Kuhlenkamp JF, Lu SC, Walsh JP, Andersen JK. PMID: 15698635.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    168. Polycystic ovarian syndrome: marked differences between endocrinologists and gynaecologists in diagnosis and management. Clin Endocrinol (Oxf). 2005 Mar; 62(3):289-95. Cussons AJ, Stuckey BG, Walsh JP, Burke V, Norman RJ. PMID: 15730409.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    169. Paget's disease of bone. Med J Aust. 2004 Sep 06; 181(5):262-5. Walsh JP. PMID: 15347275.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    170. Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder. Arch Gen Psychiatry. 2004 Jul; 61(7):649-57. Woo TU, Walsh JP, Benes FM. PMID: 15237077.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansCells
    171. A randomized clinical trial comparing oral alendronate and intravenous pamidronate for the treatment of Paget's disease of bone. Bone. 2004 Apr; 34(4):747-54. Walsh JP, Ward LC, Stewart GO, Will RK, Criddle RA, Prince RL, Stuckey BG, Dhaliwal SS, Bhagat CI, Retallack RW, Kent GN, Drury PJ, Vasikaran S, Gutteridge DH. PMID: 15050907.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    172. Combined thyroxine/liothyronine treatment does not improve well-being, quality of life, or cognitive function compared to thyroxine alone: a randomized controlled trial in patients with primary hypothyroidism. J Clin Endocrinol Metab. 2003 Oct; 88(10):4543-50. Walsh JP, Shiels L, Lim EM, Bhagat CI, Ward LC, Stuckey BG, Dhaliwal SS, Chew GT, Bhagat MC, Cussons AJ. PMID: 14557419.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCTClinical Trials
    173. Differences between endocrine surgeons and endocrinologists in the management of non-toxic multinodular goitre. Br J Surg. 2003 Sep; 90(9):1103-12. Bhagat MC, Dhaliwal SS, Bonnema SJ, Hegedüs L, Walsh JP. PMID: 12945078.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    174. Dissatisfaction with thyroxine therapy - could the patients be right? Curr Opin Pharmacol. 2002 Dec; 2(6):717-22. Walsh JP. PMID: 12482736.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    175. Corticostriatal paired-pulse potentiation produced by voltage-dependent activation of NMDA receptors and L-type Ca(2+) channels. J Neurophysiol. 2002 Jan; 87(1):157-65. Akopian G, Walsh JP. PMID: 11784738.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    176. Short-term plasticity at inhibitory synapses in rat striatum and its effects on striatal output. J Neurophysiol. 2001 May; 85(5):2088-99. Fitzpatrick JS, Akopian G, Walsh JP. PMID: 11353025.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    177. What is the optimal treatment for hypothyroidism? Med J Aust. 2001 Feb 05; 174(3):141-3. Walsh JP, Stuckey BG. PMID: 11247618.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    178. Regional differences in the expression of corticostriatal synaptic plasticity. Neuroscience. 2001; 106(1):95-101. Smith R, Musleh W, Akopian G, Buckwalter G, Walsh JP. PMID: 11564420.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    179. Functional state of corticostriatal synapses determines their expression of short- and long-term plasticity. Synapse. 2000 Dec 01; 38(3):271-80. Akopian G, Musleh W, Smith R, Walsh JP. PMID: 11020230.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    180. Management of Graves' disease in Australia. Aust N Z J Med. 2000 Oct; 30(5):559-66. Walsh JP. PMID: 11108065.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    181. Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures. Exp Neurol. 2000 Aug; 164(2):257-68. Jiang D, Akopian G, Ho YS, Walsh JP, Andersen JK. PMID: 10915565.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    182. Neurotrophin-4/5 promotes dendritic outgrowth and calcium currents in cultured mesencephalic dopamine neurons. Neuroscience. 2000; 99(2):297-304. DeFazio RA, Pong K, Knusel B, Walsh JP. PMID: 10938435.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    183. Modulation of long-term synaptic plasticity at excitatory striatal synapses. Neuroscience. 1999 Mar; 90(3):1031-41. Dos Santos Villar F, Walsh JP. PMID: 10218802.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    184. Intrinsic and synaptic properties of neurons in the vocal-control nucleus IMAN from in vitro slice preparations of juvenile and adult zebra finches. J Neurobiol. 1998 Dec; 37(4):642-58. Bottjer SW, Brady JD, Walsh JP. PMID: 9858265.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    185. Age-related change in short-term synaptic plasticity intrinsic to excitatory striatal synapses. Synapse. 1997 Sep; 27(1):57-68. Ou X, Buckwalter G, McNeill TH, Walsh JP. PMID: 9268065.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    186. Aging decreases rebound synaptic excitation produced by removal of NMDA receptor block in the striatum. Exp Brain Res. 1997 May; 114(3):590-4. Ou X, Walsh JP. PMID: 9187295.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    187. Decreased duration of Ca(2+)-mediated plateau potentials in striatal neurons from aged rats. J Neurophysiol. 1996 Oct; 76(4):2353-63. Dunia R, Buckwalter G, Defazio T, Villar FD, McNeill TH, Walsh JP. PMID: 8899609.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    188. 'Intact' dopaminergic midbrain neurons of the rat display unclamped dendritic Ca2+ currents. Neurosci Lett. 1996 Apr 12; 208(1):29-32. DeFazio T, Walsh JP. PMID: 8731167.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    189. Loss of paired-pulse facilitation at the corticostriatal synapse of the aged rat. Synapse. 1994 May; 17(1):36-42. Walsh JP, Ou X. PMID: 8042145.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    190. Synaptic activation of N-methyl-D-aspartate receptors induces short-term potentiation at excitatory synapses in the striatum of the rat. Neuroscience. 1993 Nov; 57(2):241-8. Walsh JP, Dunia R. PMID: 8115036.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    191. Evidence for enhanced synaptic excitation in transplanted neostriatal neurons. Exp Neurol. 1993 Oct; 123(2):222-34. Siviy SM, Walsh JP, Radisavljevic Z, Cohen RW, Buchwald NA, Levine MS. PMID: 8104820.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    192. Depression of excitatory synaptic input in rat striatal neurons. Brain Res. 1993 Apr 09; 608(1):123-8. Walsh JP. PMID: 8495336.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    193. Neurophysiological maturation of cat caudate neurons: evidence from in vitro studies. Synapse. 1991 Apr; 7(4):278-90. Cepeda C, Walsh JP, Buchwald NA, Levine MS. PMID: 2042110.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    194. Neurophysiological maturation of cat substantia nigra neurons: evidence from in vitro studies. Synapse. 1991 Apr; 7(4):291-300. Walsh JP, Cepeda C, Buchwald NA, Levine MS. PMID: 2042111.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    195. Intracellular neurophysiological analysis reveals alterations in excitation in striatal neurons in aged rats. Brain Res. 1989 Aug 14; 494(2):215-26. Cepeda C, Walsh JP, Hull CD, Buchwald NA, Levine MS. PMID: 2776015.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    196. Kynurenic acid antagonizes the excitatory postsynaptic potential elicited in neostriatal neurons in the in vitro slice of the rat. Brain Res. 1989 Feb 20; 480(1-2):290-3. Walsh JP, Hull CD, Levine MS, Buchwald NA. PMID: 2713654.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    197. Dye-coupling in the neostriatum of the rat: I. Modulation by dopamine-depleting lesions. Synapse. 1989; 4(3):229-37. Cepeda C, Walsh JP, Hull CD, Howard SG, Buchwald NA, Levine MS. PMID: 2514464.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    198. Physiological and morphological characterization of striatal neurons transplanted into the striatum of adult rats. Synapse. 1988; 2(1):37-44. Walsh JP, Zhou FC, Hull CD, Fisher RS, Levine MS, Buchwald NA. PMID: 3420529.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
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