Bangyan L Stiles, PhD
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Title(s) | Professor |
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Address | PSC 402C Health Sciences Campus Los Angeles CA 90089-9121
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Phone | +1 323 442 2184 |
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vCard | Download vCard |
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Research ORNG Applications Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
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AKT1 Regulates Endoplasmic Reticulum Stress and Mediates the Adaptive Response of Pancreatic ß Cells. Mol Cell Biol. 2020 05 14; 40(11).
Peng Z, Aggarwal R, Zeng N, He L, Stiles EX, Debebe A, Chen J, Chen CY, Stiles BL. PMID: 32179553.
View in: PubMed Mentions: Fields: Translation: AnimalsCells
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Regulation of basal expression of hepatic PEPCK and G6Pase by AKT2. Biochem J. 2020 03 13; 477(5):1021-1031.
He L, Li Y, Zeng N, Stiles BL. PMID: 32096546.
View in: PubMed Mentions: Fields: Translation: AnimalsCells
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Dual-Specific Protein and Lipid Phosphatase PTEN and Its Biological Functions. Cold Spring Harb Perspect Med. 2020 01 02; 10(1).
Tu T, Chen J, Chen L, Stiles BL. PMID: 31548229.
View in: PubMed Mentions: Fields:
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Inhibiting the Hexosamine Biosynthetic Pathway Lowers O-GlcNAcylation Levels and Sensitizes Cancer to Environmental Stress. Biochemistry. 2020 Sep 01; 59(34):3169-3179.
Walter LA, Lin YH, Halbrook CJ, Chuh KN, He L, Pedowitz NJ, Batt AR, Brennan CK, Stiles BL, Lyssiotis CA, Pratt MR. PMID: 31625393.
View in: PubMed Mentions: 1 Fields:
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Extracellular vesicle microRNA quantification from plasma using an integrated microfluidic device. Commun Biol. 2019; 2:189.
Ramshani Z, Zhang C, Richards K, Chen L, Xu G, Stiles BL, Hill R, Senapati S, Go DB, Chang HC. PMID: 31123713.
View in: PubMed Mentions:
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Brain metabolic and functional alterations in a liver-specific PTEN knockout mouse model. PLoS One. 2018; 13(9):e0204043.
Patil I, Sancheti H, Stiles BL, Cadenas E. PMID: 30235271.
View in: PubMed Mentions: Fields: Translation: AnimalsCells
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PTEN: Tumor Suppressor and Metabolic Regulator. Front Endocrinol (Lausanne). 2018; 9:338.
Chen CY, Chen J, He L, Stiles BL. PMID: 30038596.
View in: PubMed Mentions:
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Mitophagy and hepatic cancer stem cells. Autophagy. 2018; 14(4):715-716.
Lee J, Liu K, Stiles B, Ou JJ. PMID: 29313421.
View in: PubMed Mentions: 3 Fields: Translation: HumansCells
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Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice. Gastroenterology. 2018 04; 154(5):1509-1523.e5.
Kopp JL, Dubois CL, Schaeffer DF, Samani A, Taghizadeh F, Cowan RW, Rhim AD, Stiles BL, Valasek M, Sander M. PMID: 29273451.
View in: PubMed Mentions: 10 Fields: Translation: HumansAnimalsCells
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Wnt/ß-catenin activation and macrophage induction during liver cancer development following steatosis. Oncogene. 2017 10 26; 36(43):6020-6029.
Debebe A, Medina V, Chen CY, Mahajan IM, Jia C, Fu D, He L, Zeng N, Stiles BW, Chen CL, Wang M, Aggarwal KR, Peng Z, Huang J, Chen J, Li M, Dong T, Atkins S, Borok Z, Yuan W, Machida K, Ju C, Kahn M, Johnson D, Stiles BL. PMID: 28671671.
View in: PubMed Mentions: 12 Fields: Translation: HumansAnimalsCells
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Crosstalk of LKB1- and PTEN-regulated signals in liver morphogenesis and tumor development. Hepatol Commun. 2017 Apr; 1(2):153-167.
Jia C, Medina V, Liu C, He L, Qian D, Taojian T, Okamoto CT, Stiles BL. PMID: 29152604.
View in: PubMed Mentions:
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Activation of hepatic stellate cell in Pten null liver injury model. Fibrogenesis Tissue Repair. 2016; 9:8.
He L, Gubbins J, Peng Z, Medina V, Fei F, Asahina K, Wang J, Kahn M, Rountree CB, Stiles BL. PMID: 27307790.
View in: PubMed Mentions:
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Maf1, A New PTEN Target Linking RNA and Lipid Metabolism. Trends Endocrinol Metab. 2016 10; 27(10):742-750.
Johnson DL, Stiles BL. PMID: 27296319.
View in: PubMed Mentions: 8 Fields: Translation: HumansAnimals
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Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage. PLoS One. 2016; 11(4):e0154152.
Shearn CT, Orlicky DJ, McCullough RL, Jiang H, Maclean KN, Mercer KE, Stiles BL, Saba LM, Ronis MJ, Petersen DR. PMID: 27124661.
View in: PubMed Mentions: 6 Fields: Translation: AnimalsCells
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Crosstalk Between Activated Myofibroblasts and ß Cells in Injured Mouse Pancreas. Pancreas. 2015 Oct; 44(7):1111-20.
Bayan JA, Peng Z, Zeng N, He L, Chen J, Stiles BL. PMID: 26333110.
View in: PubMed Mentions: 3 Fields: Translation: AnimalsCells
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High-fat diet induces hepatic insulin resistance and impairment of synaptic plasticity. PLoS One. 2015; 10(5):e0128274.
Liu Z, Patil IY, Jiang T, Sancheti H, Walsh JP, Stiles BL, Yin F, Cadenas E. PMID: 26023930.
View in: PubMed Mentions: 35 Fields: Translation: AnimalsCells
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Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism. PLoS Genet. 2014 Dec; 10(12):e1004789.
Palian BM, Rohira AD, Johnson SA, He L, Zheng N, Dubeau L, Stiles BL, Johnson DL. PMID: 25502566.
View in: PubMed Mentions: 30 Fields: Translation: HumansAnimalsCells
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A unified nomenclature and amino acid numbering for human PTEN. Sci Signal. 2014 Jul 01; 7(332):pe15.
Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, Jiang X, Lee SR, Lösche M, Malaney P, Matias-Guiu X, Molina M, Pandolfi PP, Parsons R, Pinton P, Rivas C, Rocha RM, Rodríguez MS, Ross AH, Serrano M, Stambolic V, Stiles B, Suzuki A, Tan SS, Tonks NK, Trotman LC, Wolff N, Woscholski R, Wu H, Leslie NR. PMID: 24985344.
View in: PubMed Mentions: 22 Fields: Translation: HumansCells
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Monoamine oxidase A mediates prostate tumorigenesis and cancer metastasis. J Clin Invest. 2014 Jul; 124(7):2891-908.
Wu JB, Shao C, Li X, Li Q, Hu P, Shi C, Li Y, Chen YT, Yin F, Liao CP, Stiles BL, Zhau HE, Shih JC, Chung LW. PMID: 24865426.
View in: PubMed Mentions: 53 Fields: Translation: HumansAnimalsCells
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Short term feeding of a high fat diet exerts an additive effect on hepatocellular damage and steatosis in liver-specific PTEN knockout mice. PLoS One. 2014; 9(5):e96553.
Shearn CT, Mercer KE, Orlicky DJ, Hennings L, Smathers-McCullough RL, Stiles BL, Ronis MJ, Petersen DR. PMID: 24818992.
View in: PubMed Mentions: 12 Fields: Translation: Animals
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Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis. Hepatology. 2014 Mar; 59(3):947-57.
Chen WT, Tseng CC, Pfaffenbach K, Kanel G, Luo B, Stiles BL, Lee AS. PMID: 24027047.
View in: PubMed Mentions: 25 Fields: Translation: HumansAnimalsCells
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Adult-onset deletion of Pten increases islet mass and beta cell proliferation in mice. Diabetologia. 2014 Feb; 57(2):352-61.
Yang KT, Bayan JA, Zeng N, Aggarwal R, He L, Peng Z, Kassa A, Kim M, Luo Z, Shi Z, Medina V, Boddupally K, Stiles BL. PMID: 24162585.
View in: PubMed Mentions: 10 Fields: Translation: AnimalsCells
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GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN. Oncogene. 2014 Oct 16; 33(42):4997-5005.
Chen WT, Zhu G, Pfaffenbach K, Kanel G, Stiles B, Lee AS. PMID: 24141775.
View in: PubMed Mentions: 30 Fields: Translation: HumansAnimalsCells
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Extracellular heat shock protein 90 signals through subdomain II and the NPVY motif of LRP-1 receptor to Akt1 and Akt2: a circuit essential for promoting skin cell migration in vitro and wound healing in vivo. Mol Cell Biol. 2013 Dec; 33(24):4947-59.
Tsen F, Bhatia A, O'Brien K, Cheng CF, Chen M, Hay N, Stiles B, Woodley DT, Li W. PMID: 24126057.
View in: PubMed Mentions: 22 Fields: Translation: AnimalsCells
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PTEN controls ß-cell regeneration in aged mice by regulating cell cycle inhibitor p16ink4a. Aging Cell. 2013 Dec; 12(6):1000-11.
Zeng N, Yang KT, Bayan JA, He L, Aggarwal R, Stiles JW, Hou X, Medina V, Abad D, Palian BM, Al-Abdullah I, Kandeel F, Johnson DL, Stiles BL. PMID: 23826727.
View in: PubMed Mentions: 22 Fields: Translation: HumansAnimalsCells
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Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor a (ERRa). J Biol Chem. 2013 Aug 30; 288(35):25007-24.
Li Y, He L, Zeng N, Sahu D, Cadenas E, Shearn C, Li W, Stiles BL. PMID: 23836899.
View in: PubMed Mentions: 24 Fields: Translation: HumansAnimalsCells
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PI3K/AKT signaling regulates bioenergetics in immortalized hepatocytes. Free Radic Biol Med. 2013 Jul; 60:29-40.
Li C, Li Y, He L, Agarwal AR, Zeng N, Cadenas E, Stiles BL. PMID: 23376468.
View in: PubMed Mentions: 21 Fields: Translation: AnimalsCells
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Autophagy: resetting glutamine-dependent metabolism and oxygen consumption. Autophagy. 2012 Oct; 8(10):1477-93.
Lin TC, Chen YR, Kensicki E, Li AY, Kong M, Li Y, Mohney RP, Shen HM, Stiles B, Mizushima N, Lin LI, Ann DK. PMID: 22906967.
View in: PubMed Mentions: 27 Fields: Translation: AnimalsCells
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miR-200b restoration and DNA methyltransferase inhibitor block lung metastasis of mesenchymal-phenotype hepatocellular carcinoma. Oncogenesis. 2012 Jun 11; 1:e15.
Ding W, Dang H, You H, Steinway S, Takahashi Y, Wang HG, Liao J, Stiles B, Albert R, Rountree CB. PMID: 23552699.
View in: PubMed Mentions:
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Apolipoprotein B secretion is regulated by hepatic triglyceride, and not insulin, in a model of increased hepatic insulin signaling. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):236-46.
Moon BC, Hernandez-Ono A, Stiles B, Wu H, Ginsberg HN. PMID: 22155452.
View in: PubMed Mentions: 10 Fields: Translation: AnimalsCells
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Adaptive basal phosphorylation of eIF2a is responsible for resistance to cellular stress-induced cell death in Pten-null hepatocytes. Mol Cancer Res. 2011 Dec; 9(12):1708-17.
Zeng N, Li Y, He L, Xu X, Galicia V, Deng C, Stiles BL. PMID: 22009178.
View in: PubMed Mentions: 15 Fields: Translation: AnimalsCells
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Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice. Hepatology. 2010 Dec; 52(6):2096-108.
Ko KS, Tomasi ML, Iglesias-Ara A, French BA, French SW, Ramani K, Lozano JJ, Oh P, He L, Stiles BL, Li TW, Yang H, Martínez-Chantar ML, Mato JM, Lu SC. PMID: 20890892.
View in: PubMed Mentions: 50 Fields: Translation: HumansAnimalsCells
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Expansion of hepatic tumor progenitor cells in Pten-null mice requires liver injury and is reversed by loss of AKT2. Gastroenterology. 2010 Dec; 139(6):2170-82.
Galicia VA, He L, Dang H, Kanel G, Vendryes C, French BA, Zeng N, Bayan JA, Ding W, Wang KS, French S, Birnbaum MJ, Rountree CB, Stiles BL. PMID: 20837017.
View in: PubMed Mentions: 44 Fields: Translation: AnimalsCells
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Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. Hepatology. 2010 Sep; 52(3):945-53.
Ding W, You H, Dang H, LeBlanc F, Galicia V, Lu SC, Stiles B, Rountree CB. PMID: 20564331.
View in: PubMed Mentions: 66 Fields: Translation: AnimalsCells
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The critical role of AKT2 in hepatic steatosis induced by PTEN loss. Am J Pathol. 2010 May; 176(5):2302-8.
He L, Hou X, Kanel G, Zeng N, Galicia V, Wang Y, Yang J, Wu H, Birnbaum MJ, Stiles BL. PMID: 20348245.
View in: PubMed Mentions: 41 Fields: Translation: HumansAnimalsCells
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The Role of PTEN in ß-Cell Growth. Open Endocrinol J. 2010; 4:23-32.
Zeng N, Bayan JA, He L, Stiles B. PMID: 23853672.
View in: PubMed Mentions:
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PI-3-K and AKT: Onto the mitochondria. Adv Drug Deliv Rev. 2009 Nov 30; 61(14):1276-82.
Stiles BL. PMID: 19720099.
View in: PubMed Mentions: 43 Fields: Translation: HumansCells
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Expansion of CD133-expressing liver cancer stem cells in liver-specific phosphatase and tensin homolog deleted on chromosome 10-deleted mice. Stem Cells. 2009 Feb; 27(2):290-9.
Rountree CB, Ding W, He L, Stiles B. PMID: 19008348.
View in: PubMed Mentions: 46 Fields: Translation: AnimalsCells
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Phosphatase and tensin homologue deleted on chromosome 10: extending its PTENtacles. Int J Biochem Cell Biol. 2009 Apr; 41(4):757-61.
Stiles BL. PMID: 18950730.
View in: PubMed Mentions: 29 Fields: Translation: HumansAnimalsCells
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Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies. Proc Natl Acad Sci U S A. 2008 Sep 23; 105(38):14459-64.
Valamehr B, Jonas SJ, Polleux J, Qiao R, Guo S, Gschweng EH, Stiles B, Kam K, Luo TJ, Witte ON, Liu X, Dunn B, Wu H. PMID: 18791068.
View in: PubMed Mentions: 43 Fields: Translation: HumansAnimalsCells
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Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J Clin Invest. 2006 Jul; 116(7):1843-52.
Xu X, Kobayashi S, Qiao W, Li C, Xiao C, Radaeva S, Stiles B, Wang RH, Ohara N, Yoshino T, LeRoith D, Torbenson MS, Gores GJ, Wu H, Gao B, Deng CX. PMID: 16767220.
View in: PubMed Mentions: 84 Fields: Translation: HumansAnimalsCells
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Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol. 2006 Apr; 26(7):2772-81.
Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J, Magnuson MA, Wu H. PMID: 16537919.
View in: PubMed Mentions: 54 Fields: Translation: AnimalsCells
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Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell. 2005 Sep; 8(3):185-95.
Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y. PMID: 16169464.
View in: PubMed Mentions: 130 Fields: Translation: Animals
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Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue. Mol Cell Biol. 2005 Mar; 25(6):2498-510.
Kurlawalla-Martinez C, Stiles B, Wang Y, Devaskar SU, Kahn BB, Wu H. PMID: 15743841.
View in: PubMed Mentions: 57 Fields: Translation: AnimalsCells
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PTENless means more. Dev Biol. 2004 Sep 15; 273(2):175-84.
Stiles B, Groszer M, Wang S, Jiao J, Wu H. PMID: 15328005.
View in: PubMed Mentions: 99 Fields: Translation: HumansAnimalsCells
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MicroPET imaging of Cre-loxP-mediated conditional activation of a herpes simplex virus type 1 thymidine kinase reporter gene. Gene Ther. 2004 Apr; 11(7):609-18.
Sundaresan G, Paulmurugan R, Berger F, Stiles B, Nagayama Y, Wu H, Gambhir SS. PMID: 14724687.
View in: PubMed Mentions: 6 Fields: Translation: AnimalsCells
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Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7):2082-7.
Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H. PMID: 14769918.
View in: PubMed Mentions: 155 Fields: Translation: AnimalsCells
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Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis. Mol Cell Biol. 2002 Jun; 22(11):3842-51.
Stiles B, Gilman V, Khanzenzon N, Lesche R, Li A, Qiao R, Liu X, Wu H. PMID: 11997518.
View in: PubMed Mentions: 47 Fields: Translation: HumansAnimalsCells
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Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10314-9.
Neshat MS, Mellinghoff IK, Tran C, Stiles B, Thomas G, Petersen R, Frost P, Gibbons JJ, Wu H, Sawyers CL. PMID: 11504908.
View in: PubMed Mentions: 269 Fields: Translation: HumansAnimalsCells
This graph shows the total number of publications by year. To see the data as text, click here.
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Year | Publications |
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2001 | 1 | 2002 | 1 | 2004 | 3 | 2005 | 2 | 2006 | 2 | 2008 | 2 | 2009 | 2 | 2010 | 5 | 2011 | 2 | 2012 | 2 | 2013 | 6 | 2014 | 5 | 2015 | 2 | 2016 | 3 | 2017 | 3 | 2018 | 3 | 2019 | 2 | 2020 | 3 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
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