Jing-Hsiung James Ou, PhD

Title(s)Interim Chair and Professor of Molecular Microbiology & Immunology, Fletcher Jones Foundation Chair in Molecular Microbiology and Immunology
SchoolKeck School of Medicine of Usc
AddressHMR 402A 2011 Zonal Avenue
Health Sciences Campus
Los Angeles CA 90089
Phone+1 323 442 1720
ORCID ORCID Icon0000-0002-8274-5705 Additional info
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    Collapse Biography 
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    National Taiwan University, TaiwanB.S.06/1976Zoology
    California Institute of Technology, Pasadena, CaliforniaPh.D.06/1982Molecular Virology

    Collapse Overview 
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    The research of our laboratory is centered on hepatitis B virus (HBV), hepatitis C virus (HCV), and liver cancer. We are particularly interested in understanding how these two viruses interact with their host cells, how they invaded host immunity to establish persistent infection, and how they cause liver diseases including hepatocellular carcinoma.
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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hepatitis B virus e antigen induces atypical metabolism and differentially regulates programmed cell deaths of macrophages. PLoS Pathog. 2024 Mar; 20(3):e1012079. Li Y, Wu C, Lee J, Ning Q, Lim J, Eoh H, Wang S, Hurrell BP, Akbari O, Ou JJ. PMID: 38466743; PMCID: PMC10957081.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Regulation of Mitochondrial Metabolism by Hepatitis B Virus. Viruses. 2023 Nov 30; 15(12). Li Y, Ou JJ. PMID: 38140600; PMCID: PMC10747323.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. β-CATENIN stabilizes HIF2 through lncRNA and inhibits intravenous immunoglobulin immunotherapy. Front Immunol. 2023; 14:1204907. Nakagawa C, Kadlera Nagaraj M, Hernandez JC, Uthay Kumar DB, Shukla V, Machida R, Schüttrumpf J, Sher L, Farci P, Mishra L, Tahara SM, Ou JJ, Machida K. PMID: 37744383; PMCID: PMC10516572.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Enhancing autophagy in CD11c+ antigen-presenting cells as a therapeutic strategy for acute respiratory distress syndrome. Cell Rep. 2023 08 29; 42(8):112990. Quach C, Helou DG, Li M, Hurrell BP, Howard E, Shafiei-Jahani P, Soroosh P, Ou JJ, Razani B, Rehan V, Akbari O. PMID: 37590140; PMCID: PMC10510741.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Pathogenicity and virulence of Hepatitis B virus. Virulence. 2022 12; 13(1):258-296. Chuang YC, Tsai KN, Ou JJ. PMID: 35100095; PMCID: PMC8812780.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    6. Regulation of hepatitis B virus replication by autophagic membranes. Autophagy. 2023 04; 19(4):1357-1358. Chuang YC, James Ou JH. . PMID: 36037301; PMCID: PMC10012931.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Autophagic membranes participate in hepatitis B virus nucleocapsid assembly, precore and core protein trafficking, and viral release. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2201927119. Chu JYK, Chuang YC, Tsai KN, Pantuso J, Ishida Y, Saito T, Ou JJ. PMID: 35858426; PMCID: PMC9335259.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep. 2022 Jul 05; 40(1):111068. Li Y, Zhu Y, Feng S, Ishida Y, Chiu TP, Saito T, Wang S, Ann DK, Ou JJ. PMID: 35793631; PMCID: PMC9290440.
      View in: PubMed   Mentions:    Fields:    
    9. Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model. STAR Protoc. 2022 06 17; 3(2):101364. Li Y, Lee J, Helou DG, Akbari O, Ou JJ. PMID: 35573478; PMCID: PMC9097500.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    10. Biographical Feature: James H. Strauss, Jr. (1938-2021). J Virol. 2022 05 11; 96(9):e0015522. Ou JJ, Kuhn RJ, Lopez S, Rice CM. PMID: 35404100; PMCID: PMC9093126.
      View in: PubMed   Mentions:    Fields:    
    11. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3. Cell Rep. 2022 01 25; 38(4):110284. Li Y, Zhu Y, Feng S, Ishida Y, Chiu TP, Saito T, Wang S, Ann DK, Ou JJ. PMID: 35081341; PMCID: PMC8830375.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    12. Hepatitis B virus e antigen and viral persistence. Curr Opin Virol. 2021 12; 51:158-163. Tsai KN, Ou JJ. PMID: 34717215; PMCID: PMC8643334.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsPHPublic Health
    13. Regulators of liver cancer stem cells. World J Stem Cells. 2021 Aug 26; 13(8):1127-1133. Liu K, Ou JJ. PMID: 34567430; PMCID: PMC8422929.
      View in: PubMed   Mentions: 3  
    14. Autophagy in HCV Replication and Protein Trafficking. Int J Mol Sci. 2021 Jan 22; 22(3). Chu JYK, Ou JJ. PMID: 33499186; PMCID: PMC7865906.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    15. Mechanisms of Hepatitis B Virus-Induced Hepatocarcinogenesis. Recent Results Cancer Res. 2021; 217:47-70. Lee J, Tsai KN, Ou JJ. PMID: 33200361.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. Hepatitis C Virus Induces the Ubiquitin-Editing Enzyme A20 via Depletion of the Transcription Factor Upstream Stimulatory Factor 1 To Support Its Replication. mBio. 2019 07 23; 10(4). Lee J, Chan ST, Kim JY, Ou JJ. PMID: 31337730; PMCID: PMC6650561.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    17. Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance. J Virol. 2019 04 15; 93(8). Bang BR, Li M, Tsai KN, Aoyagi H, Lee SA, Machida K, Aizaki H, Jung JU, Ou JJ, Saito T. PMID: 30728260; PMCID: PMC6450116.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    18. Hepatitis B Virus-Specific T Cells as a Biomarker for Discontinuation of Nucleos(t)ide Analogue Therapy for Chronic Hepatitis B. Hepatology. 2019 03; 69(3):1342-1344. Tian Y, James Ou JH. . PMID: 30168616; PMCID: PMC6393196.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    19. Regulation of Apolipoprotein E Trafficking by Hepatitis C Virus-Induced Autophagy. J Virol. 2018 07 15; 92(14). Kim JY, Ou JJ. PMID: 29695434; PMCID: PMC6026764.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    20. Mitophagy and hepatic cancer stem cells. Autophagy. 2018; 14(4):715-716. Lee J, Liu K, Stiles B, Ou JJ. PMID: 29313421; PMCID: PMC5959321.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    21. Autophagy and mitophagy in hepatocarcinogenesis. Mol Cell Oncol. 2018; 5(2):e1405142. Liu K, Lee J, Ou JJ. PMID: 29487894; PMCID: PMC5821411.
      View in: PubMed   Mentions: 12  
    22. Regulation of Autophagy by Hepatitis C Virus for Its Replication. DNA Cell Biol. 2018 Apr; 37(4):287-290. Wang L, Ou JJ. PMID: 29350547; PMCID: PMC5963595.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    23. New insight into the role of autophagy in tumorigenesis. Cell Stress. 2017 Dec 04; 1(3):136-138. Tian Y, Wang L, Ou JJ. PMID: 31225443; PMCID: PMC6551633.
      View in: PubMed   Mentions: 1  
    24. Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells. Mol Cell. 2017 Oct 19; 68(2):281-292.e5. Liu K, Lee J, Kim JY, Wang L, Tian Y, Chan ST, Cho C, Machida K, Chen D, Ou JJ. PMID: 29033320; PMCID: PMC5687282.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansCells
    25. Hepatitis C Virus Induces the Localization of Lipid Rafts to Autophagosomes for Its RNA Replication. J Virol. 2017 10 15; 91(20). Kim JY, Wang L, Lee J, Ou JJ. PMID: 28747506; PMCID: PMC5625520.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    26. HCV-induced autophagosomes are generated via homotypic fusion of phagophores that mediate HCV RNA replication. PLoS Pathog. 2017 Sep; 13(9):e1006609. Wang L, Kim JY, Liu HM, Lai MMC, Ou JJ. PMID: 28931085; PMCID: PMC5621699.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    27. Mechanisms of Hepatitis B Virus Persistence. Trends Microbiol. 2018 01; 26(1):33-42. Tsai KN, Kuo CF, Ou JJ. PMID: 28823759; PMCID: PMC5741523.
      View in: PubMed   Mentions: 74     Fields:    Translation:HumansCellsPHPublic Health
    28. Hepatitis C Virus-Induced Autophagy and Host Innate Immune Response. Viruses. 2017 08 12; 9(8). Chan ST, Ou JJ. PMID: 28805674; PMCID: PMC5580481.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    29. Partial Hepatectomy and Castration of HBV Transgenic Mice. Methods Mol Biol. 2017; 1540:259-266. Tian Y, Ou JJ. PMID: 27975324.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    30. Suppression of Host Innate Immune Response by Hepatitis C Virus via Induction of Autophagic Degradation of TRAF6. J Virol. 2016 Dec 01; 90(23):10928-10935. Chan ST, Lee J, Narula M, Ou JJ. PMID: 27681126; PMCID: PMC5110169.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    31. Maternal-Derived Hepatitis B Virus e Antigen Alters Macrophage Function in Offspring to Drive Viral Persistence after Vertical Transmission. Immunity. 2016 05 17; 44(5):1204-14. Tian Y, Kuo CF, Akbari O, Ou JH. PMID: 27156385; PMCID: PMC4871724.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    32. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, et al. PMID: 26799652; PMCID: PMC4835977.
      View in: PubMed   Mentions: 2788     Fields:    Translation:HumansAnimals
    33. Hepatitis C virus and autophagy. Biol Chem. 2015 Nov; 396(11):1215-22. Wang L, Ou JH. PMID: 26024249; PMCID: PMC4778564.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    34. TNF-α Induced by Hepatitis C Virus via TLR7 and TLR8 in Hepatocytes Supports Interferon Signaling via an Autocrine Mechanism. PLoS Pathog. 2015 May; 11(5):e1004937. Lee J, Tian Y, Chan ST, Kim JY, Cho C, Ou JH. PMID: 26023919; PMCID: PMC4449221.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansCells
    35. Genetic and epigenetic alterations in hepatitis B virus-associated hepatocellular carcinoma. Virol Sin. 2015 Apr; 30(2):85-91. Tian Y, Ou JH. PMID: 25862579; PMCID: PMC5637728.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    36. Oncogenic viruses and cancer. Virol Sin. 2015 Apr; 30(2):83-4. Luo GG, Ou JH. PMID: 25924992; PMCID: PMC4731227.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    37. HCV induces the expression of Rubicon and UVRAG to temporally regulate the maturation of autophagosomes and viral replication. PLoS Pathog. 2015 Mar; 11(3):e1004764. Wang L, Tian Y, Ou JH. PMID: 25807108; PMCID: PMC4373777.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansCells
    38. Technical standards for hepatitis B virus X protein (HBx) research. Hepatology. 2015 Apr; 61(4):1416-24. Slagle BL, Andrisani OM, Bouchard MJ, Lee CG, Ou JH, Siddiqui A. PMID: 25099228; PMCID: PMC4320676.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    39. Autophagy, a double-edged sword in hepatocarcinogenesis. Mol Cell Oncol. 2015 Oct-Dec; 2(4):e1004968. Tian Y, Wang L, Ou JH. PMID: 27308502; PMCID: PMC4905348.
      View in: PubMed   Mentions: 2  
    40. Autophagy inhibits oxidative stress and tumor suppressors to exert its dual effect on hepatocarcinogenesis. Cell Death Differ. 2015 Jun; 22(6):1025-34. Tian Y, Kuo CF, Sir D, Wang L, Govindarajan S, Petrovic LM, Ou JH. PMID: 25526090; PMCID: PMC4423188.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    41. Virus control goes epigenetic. PLoS Pathog. 2014 Sep; 10(9):e1004370. Ou JH. PMID: 25211140; PMCID: PMC4161466.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    42. Functions of autophagy in normal and diseased liver. Autophagy. 2013 Aug; 9(8):1131-58. Czaja MJ, Ding WX, Donohue TM, Friedman SL, Kim JS, Komatsu M, Lemasters JJ, Lemoine A, Lin JD, Ou JH, Perlmutter DH, Randall G, Ray RB, Tsung A, Yin XM. PMID: 23774882; PMCID: PMC3748187.
      View in: PubMed   Mentions: 231     Fields:    Translation:HumansAnimals
    43. Transient activation of the PI3K-AKT pathway by hepatitis C virus to enhance viral entry. J Biol Chem. 2012 Dec 07; 287(50):41922-30. Liu Z, Tian Y, Machida K, Lai MM, Luo G, Foung SK, Ou JH. PMID: 23095753; PMCID: PMC3516739.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    44. Hepatitis C virus translation preferentially depends on active RNA replication. PLoS One. 2012; 7(8):e43600. Liu HM, Aizaki H, Machida K, Ou JH, Lai MM. PMID: 22937067; PMCID: PMC3427374.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    45. Viral-load-dependent effects of liver injury and regeneration on hepatitis B virus replication in mice. J Virol. 2012 Sep; 86(18):9599-605. Tian Y, Chen WL, Kuo CF, Ou JH. PMID: 22718822; PMCID: PMC3446606.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    46. Hepatitis B virus alters the antioxidant system in transgenic mice and sensitizes hepatocytes to Fas signaling. PLoS One. 2012; 7(5):e36818. Wang Q, Na B, Ou JH, Pulliam L, Yen TS. PMID: 22606292; PMCID: PMC3350475.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    47. Effects of Lipofectamine 2000/siRNA complexes on autophagy in hepatoma cells. Mol Biotechnol. 2012 May; 51(1):1-8. Mo RH, Zaro JL, Ou JH, Shen WC. PMID: 21660602; PMCID: PMC5469361.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    48. Replication of hepatitis C virus RNA on autophagosomal membranes. J Biol Chem. 2012 May 25; 287(22):18036-43. Sir D, Kuo CF, Tian Y, Liu HM, Huang EJ, Jung JU, Machida K, Ou JH. PMID: 22496373; PMCID: PMC3365724.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
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    115. Comparative studies of the core gene products of two different hepatitis C virus isolates: two alternative forms determined by a single amino acid substitution. Virology. 1994 Feb 15; 199(1):124-31. Lo SY, Selby M, Tong M, Ou JH. PMID: 8116235.
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    116. Cell cycle regulation of nuclear localization of hepatitis B virus core protein. Proc Natl Acad Sci U S A. 1993 Jul 15; 90(14):6459-63. Yeh CT, Wong SW, Fung YK, Ou JH. PMID: 8341655; PMCID: PMC46951.
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    117. Hepatocyte-specific expression of the hepatitis B virus core promoter depends on both positive and negative regulation. Mol Cell Biol. 1993 Jan; 13(1):443-8. Guo W, Chen M, Yen TS, Ou JH. PMID: 8417343; PMCID: PMC358924.
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    118. Brefeldin A as a regulator of grp78 gene expression in mammalian cells. J Biol Chem. 1992 Apr 05; 267(10):7128-33. Liu ES, Ou JH, Lee AS. PMID: 1551919.
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    119. Characterization of nuclear targeting signal of hepatitis delta antigen: nuclear transport as a protein complex. J Virol. 1992 Feb; 66(2):914-21. Xia YP, Yeh CT, Ou JH, Lai MM. PMID: 1731113; PMCID: PMC240792.
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    120. Characterization of the hepatitis B virus EnhI enhancer and X promoter complex. J Virol. 1991 Dec; 65(12):6686-92. Guo WT, Bell KD, Ou JH. PMID: 1658368; PMCID: PMC250743.
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    121. Proteolytic conversion of hepatitis B virus e antigen precursor to end product occurs in a postendoplasmic reticulum compartment. J Virol. 1991 Sep; 65(9):5080-3. Wang J, Lee AS, Ou JH. PMID: 1870212; PMCID: PMC248973.
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    122. Phosphorylation of hepatitis B virus precore and core proteins. J Virol. 1991 May; 65(5):2327-31. Yeh CT, Ou JH. PMID: 1850014; PMCID: PMC240583.
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