Lucio Comai, PhD

Title(s)Professor of Molecular Microbiology and Immunology and Biochemistry and Molecular Medicine
SchoolKeck School of Medicine of Usc
AddressHMR 700A 2011 Zonal Ave.
Health Sciences Campus
Los Angeles CA 90089
Phone+1 323 442 3950
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    Other Positions
    Title(s)Director of BSL-3 Laboratory


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    Dr. Comai received his Ph.D.in Biochemistry in 1990 from the University of California, Davis and completed his postdoctoral training at University of California, Berkeley. He joined the faculty of the Keck School of Medicine in 1995 and became a member of the Institute for Genetic Medicine in 2005.

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    Development and validation of a cell-based assay system to identify novel therapeutics for C9ALS/FTD
    NIH R21NS112950Apr 1, 2020 - Sep 30, 2021
    Role: Principal Investigator
    A destabilizing mechanism of expanded trinucleotide repeats as a potential therapeutic strategy for myotonic dystrophy
    NIH R03NS107724Mar 1, 2019 - Feb 28, 2021
    Role: Principal Investigator
    Identification of Therapeutic Small Molecules for Myotonic Dystrophy Type 1
    NIH R21NS077722Sep 30, 2011 - Aug 31, 2014
    Role: Co-Principal Investigator
    Role of the Werner syndrome protein complex in the metabolism of chromosome ends
    NIH R01AG034156Apr 1, 2010 - Aug 31, 2016
    Role: Principal Investigator
    Biochemical analyses of muscleblind complexes in myotonic dystrophy
    NIH R01NS060839Feb 1, 2007 - Nov 30, 2014
    Role: Co-Principal Investigator
    The Werner syndrome protein in CPT-induced DNA damage
    NIH R01AG023873Jun 1, 2004 - May 31, 2010
    Role: Principal Investigator
    Viral regulation of ribosomal RNA transcription
    NIH R01GM053949Jan 1, 1998 - Aug 31, 2010
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Differential Outcomes of Infection by Wild-Type SARS-CoV-2 and the B.1.617.2 and B.1.1.529 Variants of Concern in K18-hACE2 Transgenic Mice. Viruses. 2023 12 29; 16(1). He Y, Henley J, Sell P, Comai L. PMID: 38257760; PMCID: PMC10820160.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Mbnl2 loss alters novel context processing and impairs object recognition memory. iScience. 2023 May 19; 26(5):106732. Khandelwal A, Cushman J, Choi J, Zhuravka I, Rajbhandari A, Valiulahi P, Li X, Zhou C, Comai L, Reddy S. PMID: 37216102; PMCID: PMC10193234.
      View in: PubMed   Mentions: 1  
    3. Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models. PLoS Pathog. 2023 03; 19(3):e1011240. Lu H, Liu Z, Deng X, Chen S, Zhou R, Zhao R, Parandaman R, Thind A, Henley J, Tian L, Yu J, Comai L, Feng P, Yuan W. PMID: 36961850; PMCID: PMC10128965.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    4. Impedimetric Sensing: An Emerging Tool for Combating the COVID-19 Pandemic. Biosensors (Basel). 2023 Jan 30; 13(2). Ong V, Soleimani A, Amirghasemi F, Khazaee Nejad S, Abdelmonem M, Razaviyayn M, Hosseinzadeh P, Comai L, Mousavi MPS. PMID: 36831970; PMCID: PMC9953732.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    5. A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice. Front Immunol. 2022; 13:1007955. Tian J, Dillion BJ, Henley J, Comai L, Kaufman DL. PMID: 36389819; PMCID: PMC9640739.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    6. SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis. Proc Natl Acad Sci U S A. 2022 06 28; 119(26):e2122897119. Qin C, Rao Y, Yuan H, Wang TY, Zhao J, Espinosa B, Liu Y, Zhang S, Savas AC, Liu Q, Zarinfar M, Rice S, Henley J, Comai L, Graham NA, Chen C, Zhang C, Feng P. PMID: 35700355; PMCID: PMC9245715.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    7. Mbnl1 and Mbnl2 regulate brain structural integrity in mice. Commun Biol. 2021 11 30; 4(1):1342. Sta Maria NS, Zhou C, Lee SJ, Valiulahi P, Li X, Choi J, Liu X, Jacobs R, Comai L, Reddy S. PMID: 34848815; PMCID: PMC8633067.
      View in: PubMed   Mentions: 4  Translation:Animals
    8. WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells. BMC Mol Cell Biol. 2020 Oct 14; 21(1):71. Iglesias-Pedraz JM, Fossatti-Jara DM, Valle-Riestra-Felice V, Cruz-Visalaya SR, Ayala Felix JA, Comai L. PMID: 33054770; PMCID: PMC7557079.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Measurements of Hydrogen Peroxide and Oxidative DNA Damage in a Cell Model of Premature Aging. Methods Mol Biol. 2020; 2144:245-257. Iglesias-Pedraz JM, Comai L. PMID: 32410041.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation. Mol Cell Biol. 2017 02 01; 37(3). Li B, Reddy S, Comai L. PMID: 27849570; PMCID: PMC5247617.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    11. Recent advances in understanding the role of lamins in health and disease. F1000Res. 2016; 5:2536. Reddy S, Comai L. PMID: 27803806; PMCID: PMC5074355.
      View in: PubMed   Mentions: 6     Fields:    
    12. Muscleblind-like 3 deficit results in a spectrum of age-associated pathologies observed in myotonic dystrophy. Sci Rep. 2016 08 03; 6:30999. Choi J, Dixon DM, Dansithong W, Abdallah WF, Roos KP, Jordan MC, Trac B, Lee HS, Comai L, Reddy S. PMID: 27484195; PMCID: PMC4971533.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    13. Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation. EBioMedicine. 2015 Sep; 2(9):1034-47. Choi J, Personius KE, DiFranco M, Dansithong W, Yu C, Srivastava S, Dixon DM, Bhatt DB, Comai L, Vergara JL, Reddy S. PMID: 26501102; PMCID: PMC4588380.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    14. Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms. Sci Rep. 2015 Mar 12; 5:9042. Dixon DM, Choi J, El-Ghazali A, Park SY, Roos KP, Jordan MC, Fishbein MC, Comai L, Reddy S. PMID: 25761764; PMCID: PMC4356957.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    15. Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell. 2014 04; 13(2):367-78. Li B, Iglesias-Pedraz JM, Chen LY, Yin F, Cadenas E, Reddy S, Comai L. PMID: 24757718; PMCID: PMC3999508.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    16. RNA splicing is responsive to MBNL1 dose. PLoS One. 2012; 7(11):e48825. Jog SP, Paul S, Dansithong W, Tring S, Comai L, Reddy S. PMID: 23166594; PMCID: PMC3499511.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    17. A filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction. Aging (Albany NY). 2012 Aug; 4(8):567-77. Candelario J, Chen LY, Marjoram P, Reddy S, Comai L. PMID: 22948034; PMCID: PMC3461344.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    18. Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex. J Biol Chem. 2011 Nov 04; 286(44):38427-38438. Paul S, Dansithong W, Jog SP, Holt I, Mittal S, Brook JD, Morris GE, Comai L, Reddy S. PMID: 21900255; PMCID: PMC3207417.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    19. Lamin A, farnesylation and aging. Exp Cell Res. 2012 Jan 01; 318(1):1-7. Reddy S, Comai L. PMID: 21871450; PMCID: PMC4209918.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    20. RNA steady-state defects in myotonic dystrophy are linked to nuclear exclusion of SHARP. EMBO Rep. 2011 Jul 01; 12(7):735-42. Dansithong W, Jog SP, Paul S, Mohammadzadeh R, Tring S, Kwok Y, Fry RC, Marjoram P, Comai L, Reddy S. PMID: 21637295; PMCID: PMC3128970.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    21. Cell cycle-regulated association between the Werner syndrome protein and its molecular partners. Cell Cycle. 2011 Jun 15; 10(12):2038-40. Jog SP, Reddy S, Comai L. PMID: 21558813; PMCID: PMC3154421.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    22. Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells. Aging (Albany NY). 2011 Apr; 3(4):395-406. Li B, Reddy S, Comai L. PMID: 21512205; PMCID: PMC3117455.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    23. Hepatitis C virus inhibits DNA damage repair through reactive oxygen and nitrogen species and by interfering with the ATM-NBS1/Mre11/Rad50 DNA repair pathway in monocytes and hepatocytes. J Immunol. 2010 Dec 01; 185(11):6985-98. Machida K, McNamara G, Cheng KT, Huang J, Wang CH, Comai L, Ou JH, Lai MM. PMID: 20974981; PMCID: PMC3101474.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    24. Accumulation of distinct prelamin A variants in human diploid fibroblasts differentially affects cell homeostasis. Exp Cell Res. 2011 Feb 01; 317(3):319-29. Candelario J, Borrego S, Reddy S, Comai L. PMID: 20974128.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    25. Processing of human telomeres by the Werner syndrome protein. Cell Cycle. 2010 Aug 15; 9(16):3137-8. Reddy S, Li B, Comai L. PMID: 20814240; PMCID: PMC3050012.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    26. Altered nuclear functions in progeroid syndromes: a paradigm for aging research. ScientificWorldJournal. 2009 Dec 16; 9:1449-62. Li B, Jog S, Candelario J, Reddy S, Comai L. PMID: 20024518; PMCID: PMC4213125.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    27. Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain. Biochemistry. 2009 Aug 11; 48(31):7525-32. Liu Y, Stanford SM, Jog SP, Fiorillo E, Orrú V, Comai L, Bottini N. PMID: 19586056; PMCID: PMC3113683.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    28. Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activity. Aging (Albany NY). 2009 Mar 17; 1(3):289-302. Li B, Reddy S, Comai L. PMID: 20157518; PMCID: PMC2806009.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    29. Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features. PLoS One. 2008; 3(12):e3968. Dansithong W, Wolf CM, Sarkar P, Paul S, Chiang A, Holt I, Morris GE, Branco D, Sherwood MC, Comai L, Berul CI, Reddy S. PMID: 19092997; PMCID: PMC2597774.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    30. Perturbation of wild-type lamin A metabolism results in a progeroid phenotype. Aging Cell. 2008 Jun; 7(3):355-67. Candelario J, Sudhakar S, Navarro S, Reddy S, Comai L. PMID: 18363904; PMCID: PMC2527236.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    31. WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening. Mol Cell Biol. 2008 Mar; 28(6):1892-904. Li B, Jog SP, Reddy S, Comai L. PMID: 18212065; PMCID: PMC2268394.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    32. Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. J Cell Biol. 2008 Jan 14; 180(1):67-81. Madia F, Gattazzo C, Wei M, Fabrizio P, Burhans WC, Weinberger M, Galbani A, Smith JR, Nguyen C, Huey S, Comai L, Longo VD. PMID: 18195102; PMCID: PMC2213615.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    33. Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. Am J Physiol Cell Physiol. 2007 May; 292(5):C1617-24. Lin CH, Platt MD, Ficarro SB, Hoofnagle MH, Shabanowitz J, Comai L, Hunt DF, Owens GK. PMID: 17182730.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    34. CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interaction. Nucleic Acids Res. 2006; 34(17):4752-66. Lin CY, Navarro S, Reddy S, Comai L. PMID: 16971462; PMCID: PMC1635259.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    35. Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing. EMBO J. 2006 Sep 20; 25(18):4271-83. Paul S, Dansithong W, Kim D, Rossi J, Webster NJ, Comai L, Reddy S. PMID: 16946708; PMCID: PMC1570429.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    36. A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis. Nucleic Acids Res. 2005; 33(21):6861-7. Li B, Conway N, Navarro S, Comai L, Comai L. PMID: 16396834; PMCID: PMC1310904.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    37. Direct regulation of rRNA transcription by fibroblast growth factor 2. Mol Cell Biol. 2005 Nov; 25(21):9419-26. Sheng Z, Liang Y, Lin CY, Comai L, Chirico WJ. PMID: 16227592; PMCID: PMC1265826.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    38. PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. Mol Cell Biol. 2005 Aug; 25(16):6899-911. Zhang C, Comai L, Johnson DL. PMID: 16055704; PMCID: PMC1190253.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    39. Modifications of both selectivity factor and upstream binding factor contribute to poliovirus-mediated inhibition of RNA polymerase I transcription. J Gen Virol. 2005 Aug; 86(Pt 8):2315-2322. Banerjee R, Weidman MK, Navarro S, Comai L, Dasgupta A. PMID: 16033979.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    40. MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1. J Biol Chem. 2005 Feb 18; 280(7):5773-80. Dansithong W, Paul S, Comai L, Reddy S. PMID: 15546872.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    41. The Werner syndrome protein at the crossroads of DNA repair and apoptosis. Mech Ageing Dev. 2004 Aug; 125(8):521-8. Comai L, Li B. PMID: 15336909.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1. J Biol Chem. 2004 Apr 02; 279(14):13659-67. Li B, Navarro S, Kasahara N, Comai L. PMID: 14734561.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    43. Mechanism of RNA polymerase I transcription. Adv Protein Chem. 2004; 67:123-55. Comai L. PMID: 14969726.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    44. Coimmunoprecipitation assay for the detection of kinase-substrate interactions. Methods Mol Biol. 2003; 218:277-84. Comai L. PMID: 12616727.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    45. The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF. Curr Biol. 2002 Dec 23; 12(24):2142-6. Lin CY, Tuan J, Scalia P, Bui T, Comai L. PMID: 12498690.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    46. Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein. Nucleic Acids Res. 2002 Sep 01; 30(17):3653-61. Li B, Comai L. PMID: 12202749; PMCID: PMC137412.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    47. Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex. J Biol Chem. 2001 Mar 30; 276(13):9896-902. Li B, Comai L. PMID: 11152456.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    48. Regulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-A. J Cell Biochem. 2001; 82(4):610-8. Scalia P, Heart E, Comai L, Vigneri R, Sung CK. PMID: 11500939.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    49. Functional interaction between Ku and the werner syndrome protein in DNA end processing. J Biol Chem. 2000 Sep 15; 275(37):28349-52. Li B, Comai L. PMID: 10880505.
      View in: PubMed   Mentions: 82     Fields:    Translation:Cells
    50. Repression of RNA polymerase I transcription by the tumor suppressor p53. Mol Cell Biol. 2000 Aug; 20(16):5930-8. Zhai W, Comai L. PMID: 10913176; PMCID: PMC86070.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCells
    51. Inhibition of RNA polymerase I transcription in differentiated myeloid leukemia cells by inactivation of selectivity factor 1. Cell Growth Differ. 2000 Jan; 11(1):63-70. Comai L, Song Y, Tan C, Bui T. PMID: 10672904.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    52. The nucleolus: a paradigm for cell proliferation and aging. Braz J Med Biol Res. 1999 Dec; 32(12):1473-8. Comai L. PMID: 10585627.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    53. A kinase activity associated with simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1. Mol Cell Biol. 1999 Apr; 19(4):2791-802. Zhai W, Comai L. PMID: 10082545; PMCID: PMC84072.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    54. Recruitment of TATA-binding protein-TAFI complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation. Mol Cell Biol. 1999 Apr; 19(4):2872-9. Tuan JC, Zhai W, Comai L. PMID: 10082553; PMCID: PMC84080.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    55. VirE1 is a specific molecular chaperone for the exported single-stranded-DNA-binding protein VirE2 in Agrobacterium. Mol Microbiol. 1999 Mar; 31(6):1795-807. Deng W, Chen L, Peng WT, Liang X, Sekiguchi S, Gordon MP, Comai L, Nester EW. PMID: 10209751.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    56. Agrobacterium VirD2 protein interacts with plant host cyclophilins. Proc Natl Acad Sci U S A. 1998 Jun 09; 95(12):7040-5. Deng W, Chen L, Wood DW, Metcalfe T, Liang X, Gordon MP, Comai L, Nester EW. PMID: 9618535; PMCID: PMC22731.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    57. Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA. Proc Natl Acad Sci U S A. 1997 Sep 02; 94(18):9544-9. Li HP, Zhang X, Duncan R, Comai L, Lai MM. PMID: 9275159; PMCID: PMC23214.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    58. SV40 large T antigen binds to the TBP-TAF(I) complex SL1 and coactivates ribosomal RNA transcription. Genes Dev. 1997 Jun 15; 11(12):1605-17. Zhai W, Tuan JA, Comai L. PMID: 9203586.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    59. The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs. J Cell Biol. 1996 Apr; 133(2):235-46. Roussel P, André C, Comai L, Hernandez-Verdun D. PMID: 8609158; PMCID: PMC2120807.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    60. Protection of megabase DNA from shearing. Nucleic Acids Res. 1995 Oct 11; 23(19):3999-4000. Kovacic RT, Comai L, Bendich AJ. PMID: 7479050; PMCID: PMC307324.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    61. Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits. Science. 1994 Dec 23; 266(5193):2015-8. Zomerdijk JC, Beckmann H, Comai L, Tjian R. PMID: 7801130.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    62. Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. Science. 1994 Dec 23; 266(5193):1966-72. Comai L, Zomerdijk JC, Beckmann H, Zhou S, Admon A, Tjian R. PMID: 7801123.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansCells
    63. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell. 1992 Mar 06; 68(5):965-76. Comai L, Tanese N, Tjian R. PMID: 1547496.
      View in: PubMed   Mentions: 168     Fields:    Translation:HumansCells
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