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Amy Shiu Lee, PhD

Title(s)Professor of Biochemistry & Molecular Medicine
AddressNOR 5306, 5310, 5312, 5314, 5338, 1441 Eastlake Avenue
Health Sciences Campus
Los Angeles CA 90089
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    Other Positions
    Title(s)Judy and Larry Freeman Chair in Basic Science Cancer Research


    Collapse Biography 
    Collapse Awards and Honors
    University of Southern California2018Associates Award for Creativity in Research and Scholarship
    Indiana University School of Medicine2019The Mark Brothers Award
    Cell Stress Society International 2019Spirit of Budapest Pioneer Award

    Collapse Overview 
    Collapse Overview
    Dr. Amy Lee is Freeman Chair of Basic Science and Professor of Biochemistry and Molecular Medicine at the University of Southern California (USC) Norris Comprehensive Cancer Center, Los Angeles, California. Dr. Lee obtained her B.A. from the University of California, Berkeley, and her Ph.D. from the California Institute of Technology, Pasadena, California. Dr. Lee is currently holder of the Judy and Larry Freeman Cosmetics Chair in Basic Science in Cancer Research at USC. Dr. Lee’s research focuses on the mammalian stress response and molecular chaperones. Her laboratory is the first to clone the genes coding for a set of endoplasmic reticulum (ER) stress-inducible glucose regulated proteins (GRPs) and has made numerous discoveries in understanding how these genes are regulated and their role in development and human diseases. Dr. Lee’s laboratory established that GRP78 is a major contributor for tumorigenesis, metastatic growth and drug resistance. Through creation of conditional mouse models of GRP78, her laboratory provides direct proof that partial reduction of GRP78, while having no effect on normal organ function, is sufficient to halt cancer progression in vivo. GRP78 is now recognized as a novel cancer therapeutic target with dual function in tumor progression as well as tumor angiogenesis and a novel prognostic marker for tumor virulence and disease recurrence. With the recent discovery that GRP78 is preferentially expressed on the cell surface of tumor cells controlling signaling and proliferation, her laboratory is investigating the basic mechanisms for GRP translocation to the cell surface and developing therapeutics targeting the GRPs for clinical applications.

    For her research achievements, Dr. Lee received the MERIT Award from the National Cancer Institute. In recognition of her pioneering work on ER stress and its impact on cell and cancer biology, she was elected Fellow of the American Association for the Advancement of Sciences (AAAS).

    Collapse Research 
    Collapse Research Activities and Funding
    Targeting Cancer through Suppressing Stress Induction of GRP78/BiP
    NIH/NCI R01CA238029Dec 1, 2019 - Nov 30, 2022
    Role: Principal Investigator
    Role of GRP78 in beta cell adaptation in obesity and diabetes
    NIH R01DK113300Jun 1, 2018 - May 31, 2022
    Role: Co-Investigator
    Targeting Cell Surface GRP78 as a Novel Therapy for Pancreatic Cancer
    NIH/NCI R21CA179273Jun 1, 2014 - May 31, 2016
    Role: Principal Investigator
    Endoplasmic Reticulum Chaperone as a Regulator of Obesity and Diabetes
    NIH/NIDDK R01DK079999Jul 20, 2009 - Jun 30, 2012
    Role: Principal Investigator
    MECHANISM OF ANTI-APOPTOTIC FUNCTION OF GRP78/BiP
    NIH/NCI R01CA111700Aug 1, 2005 - May 31, 2010
    Role: Principal Investigator
    A NOVEL TRANSGENIC MOUSE MODEL FOR DIABETES
    NIH/NIDDK R21DK070582May 1, 2005 - Apr 30, 2008
    Role: Principal Investigator
    GROWTH REGULATION OF REPLICATION-DEPENDENT GENES
    NIH/NIGMS R01GM031138Sep 30, 1982 - May 31, 2000
    Role: Principal Investigator
    Stress Induction of Glucose Regulated Protein GRP78/BiP
    NIH/NCI R01CA027607Apr 1, 1980 - Sep 30, 2010
    Role: Principal Investigator
    COORDINATED GENE EXPRESSION IN MAMMALIAN CELLS
    NIH/NCI R37CA027607Apr 1, 1980 - Mar 31, 1996
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites
    Collapse In The News

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2020 01 15; 201(2):198-211. Borok Z, Horie M, Flodby P, Wang H, Liu Y, Ganesh S, Firth AL, Minoo P, Li C, Beers MF, Lee AS, Zhou B. PMID: 31738079.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer. Life Sci Alliance. 2019 08; 2(4). Tseng CC, Stanciauskas R, Zhang P, Woo D, Wu K, Kelly K, Gill PS, Yu M, Pinaud F, Lee AS. PMID: 31416894.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. The COOH-Terminal Proline-Rich Region of GRP78 Is a Key Regulator of Its Cell Surface Expression and Viability of Tamoxifen-Resistant Breast Cancer Cells. Neoplasia. 2019 08; 21(8):837-848. Tseng CC, Zhang P, Lee AS. PMID: 31306849.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    4. Heterozygosity of Chaperone Grp78 Reduces Intestinal Stem Cell Regeneration Potential and Protects against Adenoma Formation. Cancer Res. 2018 11 01; 78(21):6098-6106. van Lidth de Jeude JF, Spaan CN, Meijer BJ, Smit WL, Soeratram TTD, Wielenga MCB, Westendorp BF, Lee AS, Meisner S, Vermeulen JLM, Wildenberg ME, van den Brink GR, Muncan V, Heijmans J. PMID: 30232220.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Suppression of stress induction of the 78-kilodalton glucose regulated protein (GRP78) in cancer by IT-139, an anti-tumor ruthenium small molecule inhibitor. Oncotarget. 2018 Jul 03; 9(51):29698-29714. Bakewell SJ, Rangel DF, Ha DP, Sethuraman J, Crouse R, Hadley E, Costich TL, Zhou X, Nichols P, Lee AS. PMID: 30038714.
      View in: PubMed   Mentions:    Fields:    
    6. Glucose-regulated protein 78 is essential for cardiac myocyte survival. Cell Death Differ. 2018 12; 25(12):2181-2194. Wang X, Bi X, Zhang G, Deng Y, Luo X, Xu L, Scherer PE, Ferdous A, Fu G, Gillette TG, Lee AS, Jiang X, Wang ZV. PMID: 29666470.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Endoplasmic reticulum stress activates SRC, relocating chaperones to the cell surface where GRP78/CD109 blocks TGF-ß signaling. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):E4245-E4254. Tsai YL, Ha DP, Zhao H, Carlos AJ, Wei S, Pun TK, Wu K, Zandi E, Kelly K, Lee AS. PMID: 29654145.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. Endoplasmic reticulum chaperone GRP78 regulates macrophage function and insulin resistance in diet-induced obesity. FASEB J. 2018 04; 32(4):2292-2304. Kim JH, Lee E, Friedline RH, Suk S, Jung DY, Dagdeviren S, Hu X, Inashima K, Noh HL, Kwon JY, Nambu A, Huh JR, Han MS, Davis RJ, Lee AS, Lee KW, Kim JK. PMID: 29242277.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    9. New role of endoplasmic reticulum chaperones in regulating metaplasia during tumorigenesis. Mol Cell Oncol. 2017; 4(6):e1345350. Shen J, Rangel DF, Ha D, Lee AS. PMID: 29209644.
      View in: PubMed   Mentions:
    10. GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant Kras-driven pancreatic tumorigenesis in mice. Proc Natl Acad Sci U S A. 2017 05 16; 114(20):E4020-E4029. Shen J, Ha DP, Zhu G, Rangel DF, Kobielak A, Gill PS, Groshen S, Dubeau L, Lee AS. PMID: 28461470.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo. Sci Rep. 2017 03 23; 7:44723. Park KW, Eun Kim G, Morales R, Moda F, Moreno-Gonzalez I, Concha-Marambio L, Lee AS, Hetz C, Soto C. PMID: 28333162.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    12. Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice. Sci Rep. 2017 02 01; 7:40919. Lee AS, Brandhorst S, Rangel DF, Navarrete G, Cohen P, Longo VD, Chen J, Groshen S, Morgan TE, Dubeau L. PMID: 28145503.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    13. Induction of endoplasmic reticulum stress by deletion of Grp78 depletes Apc mutant intestinal epithelial stem cells. Oncogene. 2017 06 15; 36(24):3397-3405. van Lidth de Jeude JF, Meijer BJ, Wielenga MCB, Spaan CN, Baan B, Rosekrans SL, Meisner S, Shen YH, Lee AS, Paton JC, Paton AW, Muncan V, van den Brink GR, Heijmans J. PMID: 27819675.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    14. The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 07; 55(1):135-49. Flodby P, Li C, Liu Y, Wang H, Marconett CN, Laird-Offringa IA, Minoo P, Lee AS, Zhou B. PMID: 26816051.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    15. Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development. Oncotarget. 2016 Mar 22; 7(12):14885-97. Shen J, Yao L, Lin YG, DeMayo FJ, Lydon JP, Dubeau L, Lee AS. PMID: 26910913.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    16. ER Chaperone BiP/GRP78 Is Required for Myelinating Cell Survival and Provides Protection during Experimental Autoimmune Encephalomyelitis. J Neurosci. 2015 Dec 02; 35(48):15921-33. Hussien Y, Podojil JR, Robinson AP, Lee AS, Miller SD, Popko B. PMID: 26631473.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    17. GRP94 Regulates Circulating Cholesterol Levels through Blockade of PCSK9-Induced LDLR Degradation. Cell Rep. 2015 Dec 15; 13(10):2064-71. Poirier S, Mamarbachi M, Chen WT, Lee AS, Mayer G. PMID: 26628375.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    18. Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis. J Cell Physiol. 2015 Jul; 230(7):1413-20. Zhu G, Lee AS. PMID: 25546813.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    19. Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis. Oncogene. 2015 Oct; 34(43):5418-26. Lin YG, Shen J, Yoo E, Liu R, Yen HY, Mehta A, Rajaei A, Yang W, Mhawech-Fauceglia P, DeMayo FJ, Lydon J, Gill P, Lee AS. PMID: 25684138.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    20. Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface. J Biol Chem. 2015 Mar 27; 290(13):8049-64. Tsai YL, Zhang Y, Tseng CC, Stanciauskas R, Pinaud F, Lee AS. PMID: 25673690.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    21. Reply: To PMID 24027047. Hepatology. 2015 May; 61(5):1767-8. Lee AS, Chen WT. PMID: 25176452.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    22. Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged mice. Neoplasia. 2014 Aug; 16(8):617-26. Chen WT, Ha D, Kanel G, Lee AS. PMID: 25220589.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    23. Differential requirement of GRP94 and GRP78 in mammary gland development. Sci Rep. 2014 Jun 23; 4:5390. Zhu G, Wang M, Spike B, Gray PC, Shen J, Lee SH, Chen SY, Lee AS. PMID: 24953136.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    24. ER stress induces epithelial differentiation in the mouse oesophagus. Gut. 2015 Feb; 64(2):195-202. Rosekrans SL, Heijmans J, Büller NV, Westerlund J, Lee AS, Muncan V, van den Brink GR. PMID: 24789843.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    25. Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential. Nat Rev Cancer. 2014 Apr; 14(4):263-76. Lee AS. PMID: 24658275.
      View in: PubMed   Mentions: 151     Fields:    Translation:HumansAnimalsCells
    26. Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis. Hepatology. 2014 Mar; 59(3):947-57. Chen WT, Tseng CC, Pfaffenbach K, Kanel G, Luo B, Stiles BL, Lee AS. PMID: 24027047.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    27. Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production. PLoS One. 2013; 8(11):e80071. Zhang Y, Tseng CC, Tsai YL, Fu X, Schiff R, Lee AS. PMID: 24244613.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    28. GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN. Oncogene. 2014 Oct 16; 33(42):4997-5005. Chen WT, Zhu G, Pfaffenbach K, Kanel G, Stiles B, Lee AS. PMID: 24141775.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    29. Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis. Clin Cancer Res. 2013 Dec 15; 19(24):6802-11. Liu R, Li X, Gao W, Zhou Y, Wey S, Mitra SK, Krasnoperov V, Dong D, Liu S, Li D, Zhu G, Louie S, Conti PS, Li Z, Lee AS, Gill PS. PMID: 24048331.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    30. Deficiency of GRP94 in the hematopoietic system alters proliferation regulators in hematopoietic stem cells. Stem Cells Dev. 2013 Dec 01; 22(23):3062-73. Luo B, Tseng CC, Adams GB, Lee AS. PMID: 23859598.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    31. ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response. Cell Rep. 2013 Apr 25; 3(4):1128-39. Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, Ferrante M, Lee AS, Onderwater JJ, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V, van den Brink GR. PMID: 23545496.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    32. AKT inhibition mitigates GRP78 (glucose-regulated protein) expression and contribution to chemoresistance in endometrial cancers. Int J Cancer. 2013 Jul; 133(1):21-30. Gray MJ, Mhawech-Fauceglia P, Yoo E, Yang W, Wu E, Lee AS, Lin YG. PMID: 23280503.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    33. GRP78/BiP is a novel downstream target of IGF-1 receptor mediated signaling. J Cell Physiol. 2012 Dec; 227(12):3803-11. Pfaffenbach KT, Pong M, Morgan TE, Wang H, Ott K, Zhou B, Longo VD, Lee AS. PMID: 22422508.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    34. The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival. Gynecol Oncol. 2013 Mar; 128(3):552-9. Matsuo K, Gray MJ, Yang DY, Srivastava SA, Tripathi PB, Sonoda LA, Yoo EJ, Dubeau L, Lee AS, Lin YG. PMID: 23200913.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    35. GRP78 plays an essential role in adipogenesis and postnatal growth in mice. FASEB J. 2013 Mar; 27(3):955-64. Zhu G, Ye R, Jung DY, Barron E, Friedline RH, Benoit VM, Hinton DR, Kim JK, Lee AS. PMID: 23180827.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    36. miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer. Oncogene. 2013 Sep 26; 32(39):4694-701. Su SF, Chang YW, Andreu-Vieyra C, Fang JY, Yang Z, Han B, Lee AS, Liang G. PMID: 23085757.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    37. Endoplasmic reticulum stress response promotes cytotoxic phenotype of CD8aß+ intraepithelial lymphocytes in a mouse model for Crohn's disease-like ileitis. J Immunol. 2012 Aug 01; 189(3):1510-20. Chang JS, Ocvirk S, Berger E, Kisling S, Binder U, Skerra A, Lee AS, Haller D. PMID: 22753943.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    38. Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling. PLoS One. 2012; 7(6):e39047. Wey S, Luo B, Lee AS. PMID: 22723926.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    39. The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies. Oncogene. 2013 Feb 14; 32(7):805-18. Luo B, Lee AS. PMID: 22508478.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansAnimalsCells
    40. A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis. J Exp Med. 2012 Apr 09; 209(4):871-86. Yoo SA, You S, Yoon HJ, Kim DH, Kim HS, Lee K, Ahn JH, Hwang D, Lee AS, Kim KJ, Park YJ, Cho CS, Kim WU. PMID: 22430489.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    41. Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling. Blood. 2012 Jan 19; 119(3):817-25. Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS. PMID: 21937694.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    42. Soy food supplementation, dietary fat reduction and peripheral blood gene expression in postmenopausal women--a randomized, controlled trial. Mol Nutr Food Res. 2011 Sep; 55 Suppl 2:S264-77. Wang J, Siegmund K, Tseng CC, Lee AS, Wu AH. PMID: 21823222.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice. Hepatology. 2011 Jul; 54(1):229-39. Ji C, Kaplowitz N, Lau MY, Kao E, Petrovic LM, Lee AS. PMID: 21503947.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    44. Impaired eyeblink conditioning in 78 kDa-glucose regulated protein (GRP78)/immunoglobulin binding protein (BiP) conditional knockout mice. Behav Neurosci. 2011 Jun; 125(3):404-11. Kim S, Wang M, Lee AS, Thompson RF. PMID: 21517144.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    45. Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK). J Biol Chem. 2011 Jul 22; 286(29):25687-96. Zhou H, Zhang Y, Fu Y, Chan L, Lee AS. PMID: 21622563.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    46. The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche. PLoS One. 2011; 6(5):e20364. Luo B, Lam BS, Lee SH, Wey S, Zhou H, Wang M, Chen SY, Adams GB, Lee AS. PMID: 21647226.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    47. Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes. J Endocrinol. 2011 Aug; 210(2):209-17. Ye R, Ni M, Wang M, Luo S, Zhu G, Chow RH, Lee AS. PMID: 21565852.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    48. A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Res. 2011 Apr 15; 71(8):2848-57. Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS. PMID: 21467168.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    49. GRP78 promoter polymorphism rs391957 as potential predictor for clinical outcome in gastric and colorectal cancer patients. Ann Oncol. 2011 Nov; 22(11):2431-9. Winder T, Bohanes P, Zhang W, Yang D, Power DG, Ning Y, Gerger A, Wilson PM, Tang LH, Shah M, Lee AS, Lenz HJ. PMID: 21382870.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    50. Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting. Biochem J. 2011 Mar 01; 434(2):181-8. Ni M, Zhang Y, Lee AS. PMID: 21309747.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimalsCells
    51. GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy. Int J Cancer. 2011 Feb 01; 128(3):726-31. Lee E, Nichols P, Groshen S, Spicer D, Lee AS. PMID: 20473863.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    52. Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress. Mitochondrion. 2011 Mar; 11(2):279-86. Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG. PMID: 21047562.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    53. Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis. Am J Pathol. 2010 Dec; 177(6):2827-36. Ye R, Mareninova OA, Barron E, Wang M, Hinton DR, Pandol SJ, Lee AS. PMID: 20971738.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    54. The critical role of GRP78 in physiologic and pathologic stress. Curr Opin Cell Biol. 2011 Apr; 23(2):150-6. Pfaffenbach KT, Lee AS. PMID: 20970977.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    55. Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling. PLoS One. 2010 May 26; 5(5):e10852. Mao C, Wang M, Luo B, Wey S, Dong D, Wesselschmidt R, Rawlings S, Lee AS. PMID: 20520781.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    56. The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice. J Clin Invest. 2010 Jun; 120(6):1914-24. Liu M, Spellberg B, Phan QT, Fu Y, Fu Y, Lee AS, Edwards JE, Filler SG, Ibrahim AS. PMID: 20484814.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansAnimalsCells
    57. Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP. J Biol Chem. 2010 May 14; 285(20):15065-75. Zhang Y, Liu R, Ni M, Gill P, Lee AS. PMID: 20208072.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    58. The Par-4-GRP78 TRAIL, more twists and turns. Cancer Biol Ther. 2009 Nov; 8(22):2103-5. Lee AS. PMID: 19823030.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    59. Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell Death Differ. 2010 Mar; 17(3):488-98. Wang M, Ye R, Barron E, Baumeister P, Mao C, Luo S, Fu Y, Luo B, Dubeau L, Hinton DR, Lee AS. PMID: 19816510.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    60. Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance. Diabetes. 2010 Jan; 59(1):6-16. Ye R, Jung DY, Jun JY, Li J, Luo S, Ko HJ, Kim JK, Lee AS. PMID: 19808896.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    61. Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders. Antioxid Redox Signal. 2009 Sep; 11(9):2307-16. Wang M, Wey S, Zhang Y, Ye R, Lee AS. PMID: 19309259.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansCells
    62. Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP. PLoS One. 2009 Aug 31; 4(8):e6868. Ni M, Zhou H, Wey S, Baumeister P, Lee AS. PMID: 19718440.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    63. Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis. Mol Cancer Ther. 2009 May; 8(5):1086-94. Baumeister P, Dong D, Fu Y, Lee AS. PMID: 19417144.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    64. Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy. PLoS One. 2008; 3(12):e3951. Yu DH, Macdonald J, Liu G, Lee AS, Ly M, Davis T, Ke N, Zhou D, Wong-Staal F, Li QX. PMID: 19079611.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    65. Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium. Proc Natl Acad Sci U S A. 2008 Dec 09; 105(49):19444-9. Fu Y, Wey S, Wang M, Ye R, Liao CP, Roy-Burman P, Lee AS. PMID: 19033462.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    66. Glucose-regulated protein 78 as a novel effector of BRCA1 for inhibiting stress-induced apoptosis. Oncogene. 2008 Dec 04; 27(53):6782-9. Yeung BH, Kwan BW, He QY, Lee AS, Liu J, Wong AS. PMID: 18776923.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    67. Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells. Mol Cancer Res. 2008 Aug; 6(8):1268-75. Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, Ni M, Schönthal AH, Chen TC, Hofman FM, Lee AS. PMID: 18708359.
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    68. The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death Differ. 2008 Sep; 15(9):1460-71. Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS. PMID: 18551133.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansCells
    69. Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Res. 2008 Jan 15; 68(2):498-505. Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS. PMID: 18199545.
      View in: PubMed   Mentions: 145     Fields:    Translation:Animals
    70. The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Res. 2007 Oct 15; 67(20):9809-16. Pyrko P, Schönthal AH, Hofman FM, Chen TC, Lee AS. PMID: 17942911.
      View in: PubMed   Mentions: 152     Fields:    Translation:HumansCells
    71. Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival. Hum Pathol. 2007 Oct; 38(10):1547-52. Daneshmand S, Quek ML, Lin E, Lee C, Cote RJ, Hawes D, Cai J, Groshen S, Lieskovsky G, Skinner DG, Lee AS, Pinski J. PMID: 17640713.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    72. ER chaperones in mammalian development and human diseases. FEBS Lett. 2007 Jul 31; 581(19):3641-51. Ni M, Lee AS. PMID: 17481612.
      View in: PubMed   Mentions: 249     Fields:    Translation:HumansAnimalsCells
    73. GRP78 induction in cancer: therapeutic and prognostic implications. Cancer Res. 2007 Apr 15; 67(8):3496-9. Lee AS. PMID: 17440054.
      View in: PubMed   Mentions: 267     Fields:    Translation:Humans
    74. GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis. Cancer Res. 2007 Apr 15; 67(8):3734-40. Fu Y, Li J, Lee AS. PMID: 17440086.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    75. Expression of stress response protein Grp78 is associated with the development of castration-resistant prostate cancer. Clin Cancer Res. 2006 Oct 15; 12(20 Pt 1):5987-93. Pootrakul L, Datar RH, Shi SR, Cai J, Hawes D, Groshen SG, Lee AS, Cote RJ. PMID: 17062670.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    76. Constitutive nucleosome depletion and ordered factor assembly at the GRP78 promoter revealed by single molecule footprinting. PLoS Genet. 2006 Sep 22; 2(9):e160. Gal-Yam EN, Jeong S, Tanay A, Egger G, Lee AS, Jones PA. PMID: 17002502.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    77. GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer. Cancer Res. 2006 Aug 15; 66(16):7849-53. Lee E, Nichols P, Spicer D, Groshen S, Yu MC, Lee AS. PMID: 16912156.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    78. GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development. Mol Cell Biol. 2006 Aug; 26(15):5688-97. Luo S, Mao C, Lee B, Lee AS. PMID: 16847323.
      View in: PubMed   Mentions: 154     Fields:    Translation:AnimalsCells
    79. Glucose regulated proteins in cancer progression, drug resistance and immunotherapy. Cancer Biol Ther. 2006 Jul; 5(7):741-4. Fu Y, Lee AS. PMID: 16861902.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    80. ER stress and cancer. Cancer Biol Ther. 2006 Jul; 5(7):721-2. Lee AS, Hendershot LM. PMID: 16880733.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    81. Activator protein-2 overexpression accounts for increased insulin receptor expression in human breast cancer. Cancer Res. 2006 May 15; 66(10):5085-93. Paonessa F, Foti D, Costa V, Chiefari E, Brunetti G, Leone F, Luciano F, Wu F, Lee AS, Gulletta E, Fusco A, Brunetti A. PMID: 16707431.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    82. The effect of dexamethasone on defective nephrin transport caused by ER stress: a potential mechanism for the therapeutic action of glucocorticoids in the acquired glomerular diseases. Kidney Int. 2006 Apr; 69(8):1350-9. Fujii Y, Khoshnoodi J, Takenaka H, Hosoyamada M, Nakajo A, Bessho F, Kudo A, Takahashi S, Arimura Y, Yamada A, Nagasawa T, Ruotsalainen V, Tryggvason K, Lee AS, Yan K. PMID: 16531978.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    83. In vivo regulation of Grp78/BiP transcription in the embryonic heart: role of the endoplasmic reticulum stress response element and GATA-4. J Biol Chem. 2006 Mar 31; 281(13):8877-87. Mao C, Tai WC, Bai Y, Poizat C, Lee AS. PMID: 16452489.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    84. Stress induction of GRP78/BiP and its role in cancer. Curr Mol Med. 2006 Feb; 6(1):45-54. Li J, Lee AS. PMID: 16472112.
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    85. Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J Biol Chem. 2006 Mar 17; 281(11):7260-70. Li J, Lee B, Lee AS. PMID: 16407291.
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    86. Vascular targeting and antiangiogenesis agents induce drug resistance effector GRP78 within the tumor microenvironment. Cancer Res. 2005 Jul 01; 65(13):5785-91. Dong D, Ko B, Baumeister P, Swenson S, Costa F, Markland F, Stiles C, Patterson JB, Bates SE, Lee AS. PMID: 15994954.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    87. Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. Mol Cell Biol. 2005 Jun; 25(11):4529-40. Baumeister P, Luo S, Skarnes WC, Sui G, Seto E, Shi Y, Lee AS. PMID: 15899857.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    88. The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress. Methods. 2005 Apr; 35(4):373-81. Lee AS. PMID: 15804610.
      View in: PubMed   Mentions: 249     Fields:    Translation:AnimalsCells
    89. Transcriptional regulation of the Grp78 promoter by endoplasmic reticulum stress: role of TFII-I and its tyrosine phosphorylation. J Biol Chem. 2005 Apr 29; 280(17):16821-8. Hong M, Lin MY, Huang JM, Baumeister P, Hakre S, Roy AL, Lee AS. PMID: 15664986.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    90. Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo. Nat Med. 2004 Oct; 10(10):1013-4; author reply 1014. Mao C, Dong D, Little E, Luo S, Lee AS. PMID: 15459690.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    91. Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6. J Cell Biochem. 2004 Jul 01; 92(4):723-32. Hong M, Li M, Mao C, Lee AS. PMID: 15211570.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    92. Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors. Hum Gene Ther. 2004 Jun; 15(6):553-61. Dong D, Dubeau L, Bading J, Nguyen K, Luna M, Yu H, Gazit-Bornstein G, Gordon EM, Gomer C, Hall FL, Gambhir SS, Lee AS. PMID: 15212714.
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    93. ATF6 modulates SREBP2-mediated lipogenesis. EMBO J. 2004 Feb 25; 23(4):950-8. Zeng L, Lu M, Mori K, Luo S, Lee AS, Zhu Y, Shyy JY. PMID: 14765107.
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    94. Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response. J Biol Chem. 2004 Mar 19; 279(12):11354-63. Hong M, Luo S, Baumeister P, Huang JM, Gogia RK, Li M, Lee AS. PMID: 14699159.
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    95. Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements. J Biol Chem. 2003 Sep 26; 278(39):37375-85. Luo S, Baumeister P, Yang S, Abcouwer SF, Lee AS. PMID: 12871976.
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    96. Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation. J Biol Chem. 2003 Jun 06; 278(23):20915-24. Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS. PMID: 12665508.
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    97. Cancer-inducible transgene expression by the Grp94 promoter: spontaneous activation in tumors of various origins and cancer-associated macrophages. Cancer Res. 2002 Dec 15; 62(24):7207-12. Reddy RK, Dubeau L, Kleiner H, Parr T, Nichols P, Ko B, Dong D, Ko H, Mao C, DiGiovanni J, Lee AS. PMID: 12499260.
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    98. Requirement of the p38 mitogen-activated protein kinase signalling pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription factor 6 as a target for stress-induced phosphorylation. Biochem J. 2002 Sep 15; 366(Pt 3):787-95. Luo S, Lee AS. PMID: 12076252.
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    99. Enhanced photodynamic therapy efficacy with inducible suicide gene therapy controlled by the grp promoter. Cancer Res. 2002 Mar 01; 62(5):1458-61. Luna MC, Chen X, Wong S, Tsui J, Rucker N, Lee AS, Gomer CJ. PMID: 11888920.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    100. CDP and AP-2 mediated repression mechanism of the replication-dependent hamster histone H3.2 promoter. J Cell Biochem. 2002; 84(4):699-707. Wu F, Lee AS. PMID: 11835395.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    101. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci. 2001 Aug; 26(8):504-10. Lee AS. PMID: 11504627.
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    102. Identification of TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interaction with ATF6. Mol Cell Biol. 2001 May; 21(9):3220-33. Parker R, Phan T, Baumeister P, Roy B, Cheriyath V, Roy AL, Lee AS. PMID: 11287625.
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    103. YY1 as a regulator of replication-dependent hamster histone H3.2 promoter and an interactive partner of AP-2. J Biol Chem. 2001 Jan 05; 276(1):28-34. Wu F, Lee AS. PMID: 11018030.
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    104. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nat Cell Biol. 2000 Dec; 2(12):863-70. Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G. PMID: 11146649.
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    105. Heterogeneous nuclear ribonucleoproteins as regulators of gene expression through interactions with the human thymidine kinase promoter. J Cell Biochem. 2000 Sep 07; 79(3):395-406. Lau JS, Baumeister P, Kim E, Roy B, Hsieh TY, Lai M, Lee AS. PMID: 10972977.
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    106. ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. Mol Cell Biol. 2000 Jul; 20(14):5096-106. Li M, Baumeister P, Roy B, Phan T, Foti D, Luo S, Lee AS. PMID: 10866666.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    107. Eradication of murine mammary adenocarcinoma through HSVtk expression directed by the glucose-starvation inducible grp78 promoter. Breast Cancer Res Treat. 2000 Jan; 59(1):81-90. Chen X, Zhang D, Dennert G, Hung G, Lee AS. PMID: 10752683.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    108. Conservation and divergence of the yeast and mammalian unfolded protein response. Activation of specific mammalian endoplasmic reticulum stress element of the grp78/BiP promoter by yeast Hac1. J Biol Chem. 1999 Oct 22; 274(43):30402-9. Foti DM, Welihinda A, Kaufman RJ, Lee AS. PMID: 10521417.
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    109. The endoplasmic reticulum chaperone glycoprotein GRP94 with Ca(2+)-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis. J Biol Chem. 1999 Oct 01; 274(40):28476-83. Reddy RK, Lu J, Lee AS. PMID: 10497210.
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    110. Use of the glucose starvation-inducible glucose-regulated protein 78 promoter in suicide gene therapy of murine fibrosarcoma. Cancer Res. 1999 Jul 01; 59(13):3100-6. Gazit G, Hung G, Chen X, Anderson WF, Lee AS. PMID: 10397251.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    111. The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex. Nucleic Acids Res. 1999 Mar 15; 27(6):1437-43. Roy B, Lee AS. PMID: 10037803.
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    112. De-regulation of GRP stress protein expression in human breast cancer cell lines. Breast Cancer Res Treat. 1999 Mar; 54(2):135-46. Gazit G, Lu J, Lee AS. PMID: 10424404.
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    113. Identification of AP-2 as an interactive target of Rb and a regulator of the G1/S control element of the hamster histone H3.2 promoter. Nucleic Acids Res. 1998 Nov 01; 26(21):4837-45. Wu F, Lee AS. PMID: 9776742.
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    114. Hepatitis C virus core protein interacts with heterogeneous nuclear ribonucleoprotein K. J Biol Chem. 1998 Jul 10; 273(28):17651-9. Hsieh TY, Matsumoto M, Chou HC, Schneider R, Hwang SB, Lee AS, Lai MM. PMID: 9651361.
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    115. Mechanism for the suppression of the mammalian stress response by genistein, an anticancer phytoestrogen from soy. J Natl Cancer Inst. 1998 Mar 04; 90(5):381-8. Zhou Y, Lee AS. PMID: 9498488.
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    116. Positive and negative regulation of the human thymidine kinase promoter mediated by CCAAT binding transcription factors NF-Y/CBF, dbpA, and CDP/cut. Cell Growth Differ. 1997 Dec; 8(12):1329-38. Kim EC, Lau JS, Rawlings S, Lee AS. PMID: 9419421.
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    117. Endoplasmic reticulum stress-inducible protein GRP94 is associated with an Mg2+-dependent serine kinase activity modulated by Ca2+ and GRP78/BiP. J Cell Physiol. 1997 Feb; 170(2):115-29. Ramakrishnan M, Schönthal AH, Lee AS. PMID: 9009140.
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    118. Suppression of grp78 core promoter element-mediated stress induction by the dbpA and dbpB (YB-1) cold shock domain proteins. Mol Cell Biol. 1997 Jan; 17(1):61-8. Li WW, Hsiung Y, Wong V, Galvin K, Zhou Y, Shi Y, Lee AS. PMID: 8972186.
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    119. Induction of the mammalian GRP78/BiP gene by Ca2+ depletion and formation of aberrant proteins: activation of the conserved stress-inducible grp core promoter element by the human nuclear factor YY1. Mol Cell Biol. 1997 Jan; 17(1):54-60. Li WW, Hsiung Y, Zhou Y, Roy B, Lee AS. PMID: 8972185.
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    120. Identification of a set of protein species approximately 40 kDa as high-affinity DNA binding factor(s) to the cell cycle regulatory region of the human thymidine kinase promoter. Cell Growth Differ. 1996 Dec; 7(12):1741-9. Kim EC, Rawlings SL, Li LJ, Roy B, Lee AS. PMID: 8959343.
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    121. Calcium-sensitive transcriptional activation of the proximal CCAAT regulatory element of the grp78/BiP promoter by the human nuclear factor CBF/NF-Y. J Biol Chem. 1996 Nov 15; 271(46):28995-9002. Roy B, Li WW, Lee AS. PMID: 8910550.
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    122. Induction of glucose-regulated protein (glucose-regulated protein 78/BiP and glucose-regulated protein 94) and heat shock protein 70 transcripts in the immature rat brain following status epilepticus. Neuroscience. 1996 Nov; 75(1):209-19. Little E, Tocco G, Baudry M, Lee AS, Schreiber SS. PMID: 8923535.
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    123. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci U S A. 1996 Jul 23; 93(15):7690-4. Jamora C, Dennert G, Lee AS. PMID: 8755537.
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    124. Conformation-defective herpes simplex virus 1 glycoprotein B activates the promoter of the grp94 gene that codes for the 94-kD stress protein in the endoplasmic reticulum. DNA Cell Biol. 1995 May; 14(5):373-84. Ramakrishnan M, Tugizov S, Pereira L, Lee AS. PMID: 7748487.
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    125. Generation of a mammalian cell line deficient in glucose-regulated protein stress induction through targeted ribozyme driven by a stress-inducible promoter. J Biol Chem. 1995 Apr 21; 270(16):9526-34. Little E, Lee AS. PMID: 7721881.
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    126. Use of the stress-inducible grp78/BiP promoter in targeting high level gene expression in fibrosarcoma in vivo. Cancer Res. 1995 Apr 15; 55(8):1660-3. Gazit G, Kane SE, Nichols P, Lee AS. PMID: 7712471.
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    127. Transduction of calcium stress through interaction of the human transcription factor CBF with the proximal CCAAT regulatory element of the grp78/BiP promoter. Mol Cell Biol. 1995 Apr; 15(4):2263-74. Roy B, Lee AS. PMID: 7891720.
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    128. Identification of a 68 kDa protein species as a specific DNA-binding component of the H3abp complex interacting with the histone H3.2 G1/S regulatory domain. Nucleic Acids Res. 1995 Feb 11; 23(3):475-84. Naeve GS, Zhou Y, Lee AS. PMID: 7885844.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    129. Requirement of tyrosine- and serine/threonine kinases in the transcriptional activation of the mammalian grp78/BiP promoter by thapsigargin. J Biol Chem. 1995 Jan 06; 270(1):494-502. Cao X, Zhou Y, Lee AS. PMID: 7814417.
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    130. Constitutive expression of a microinjected glucose-regulated protein (grp78) fusion gene during early Xenopus laevis development. Differentiation. 1994 Sep; 57(3):171-7. Vezina C, Wooden SK, Lee AS, Heikkila JJ. PMID: 7988793.
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    131. Stress induction of the mammalian GRP78/BiP protein gene: in vivo genomic footprinting and identification of p70CORE from human nuclear extract as a DNA-binding component specific to the stress regulatory element. Mol Cell Biol. 1994 Aug; 14(8):5533-46. Li WW, Sistonen L, Morimoto RI, Lee AS. PMID: 8035828.
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    132. Localization of the gene encoding human BiP/GRP78, the endoplasmic reticulum cognate of the HSP70 family, to chromosome 9q34. Genomics. 1994 Mar 15; 20(2):281-4. Hendershot LM, Valentine VA, Lee AS, Morris SW, Shapiro DN. PMID: 8020977.
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    133. Erp61 is GRP58, a stress-inducible luminal endoplasmic reticulum protein, but is devoid of phosphatidylinositide-specific phospholipase C activity. Arch Biochem Biophys. 1994 Feb 01; 308(2):454-60. Mazzarella RA, Marcus N, Haugejorden SM, Balcarek JM, Baldassare JJ, Roy B, Li LJ, Lee AS, Green M. PMID: 8109975.
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    134. Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction. Int J Radiat Oncol Biol Phys. 1994 Feb 01; 28(3):661-6. Koong AC, Chen EY, Lee AS, Brown JM, Giaccia AJ. PMID: 8113109.
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    135. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit Rev Eukaryot Gene Expr. 1994; 4(1):1-18. Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS. PMID: 7987045.
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    136. Suppression of stress protein GRP78 induction in tumor B/C10ME eliminates resistance to cell mediated cytotoxicity. Cancer Res. 1993 Dec 15; 53(24):6001-5. Sugawara S, Takeda K, Lee A, Dennert G. PMID: 8261413.
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    137. Transactivation of the grp78 promoter by Ca2+ depletion. A comparative analysis with A23187 and the endoplasmic reticulum Ca(2+)-ATPase inhibitor thapsigargin. J Biol Chem. 1993 Jun 05; 268(16):12003-9. Li WW, Alexandre S, Cao X, Lee AS. PMID: 8505325.
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    138. Temporal regulation of cyclin A-p107 and p33cdk2 complexes binding to a human thymidine kinase promoter element important for G1-S phase transcriptional regulation. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3554-8. Li LJ, Naeve GS, Lee AS. PMID: 8475104.
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    139. A human HMG2 cDNA with a novel 3'-untranslated region. Nucleic Acids Res. 1992 Dec 11; 20(23):6413. Alexandre S, Li WW, Lee AS. PMID: 1475204.
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    140. Identification of a 10-base pair protein binding site in the promoter of the hamster H3.2 gene required for the S phase dependent increase in transcription and its interaction with a Jun-like nuclear factor. Cell Growth Differ. 1992 Dec; 3(12):919-28. Naeve GS, Sharma A, Lee AS. PMID: 1472472.
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    141. Establishment of a Chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94. J Cell Physiol. 1992 Dec; 153(3):575-82. Li LJ, Li X, Ferrario A, Rucker N, Liu ES, Wong S, Gomer CJ, Lee AS. PMID: 1332981.
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    142. Brefeldin A as a regulator of grp78 gene expression in mammalian cells. J Biol Chem. 1992 Apr 05; 267(10):7128-33. Liu ES, Ou JH, Lee AS. PMID: 1551919.
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    143. Mammalian stress response: induction of the glucose-regulated protein family. Curr Opin Cell Biol. 1992 Apr; 4(2):267-73. Lee AS. PMID: 1599691.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    144. Identification of a protein-binding site in the promoter of the human thymidine kinase gene required for the G1-S-regulated transcription. J Biol Chem. 1992 Feb 05; 267(4):2723-7. Kim YK, Lee AS. PMID: 1370831.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    145. Comparison of the genomic organizations of the rat grp78 and hsc73 gene and their evolutionary implications. DNA Seq. 1992; 3(1):41-8. Wooden SK, Lee AS. PMID: 1457808.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    146. Analysis of the expression of a glucose-regulated protein (GRP78) promoter/CAT fusion gene during early Xenopus laevis development. Differentiation. 1992 Jan; 49(1):1-6. Winning RS, Bols NC, Wooden SK, Lee AS, Heikkila JJ. PMID: 1624059.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    147. Glucose regulated protein induction and cellular resistance to oxidative stress mediated by porphyrin photosensitization. Cancer Res. 1991 Dec 15; 51(24):6574-9. Gomer CJ, Ferrario A, Rucker N, Wong S, Lee AS. PMID: 1835901.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    148. A binding site for the cyclic adenosine 3',5'-monophosphate-response element-binding protein as a regulatory element in the grp78 promoter. Mol Endocrinol. 1991 Dec; 5(12):1862-72. Alexandre S, Nakaki T, Vanhamme L, Lee AS. PMID: 1838791.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    149. Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I. Mol Cell Biol. 1991 Nov; 11(11):5612-23. Wooden SK, Li LJ, Navarro D, Qadri I, Pereira L, Lee AS. PMID: 1656235.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    150. Common sets of nuclear factors binding to the conserved promoter sequence motif of two coordinately regulated ER protein genes, GRP78 and GRP94. Nucleic Acids Res. 1991 Oct 11; 19(19):5425-31. Liu ES, Lee AS. PMID: 1923827.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    151. Proteolytic conversion of hepatitis B virus e antigen precursor to end product occurs in a postendoplasmic reticulum compartment. J Virol. 1991 Sep; 65(9):5080-3. Wang J, Lee AS, Ou JH. PMID: 1870212.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    152. Competitive inhibition of a set of endoplasmic reticulum protein genes (GRP78, GRP94, and ERp72) retards cell growth and lowers viability after ionophore treatment. Mol Cell Biol. 1991 Jul; 11(7):3446-53. Li XA, Lee AS. PMID: 2046663.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    153. Identification of a 70-base-pair cell cycle regulatory unit within the promoter of the human thymidine kinase gene and its interaction with cellular factors. Mol Cell Biol. 1991 Apr; 11(4):2296-302. Kim YK, Lee AS. PMID: 2005912.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    154. Temporal events regulating the early phases of the mammalian cell cycle. Curr Opin Cell Biol. 1991 Apr; 3(2):261-8. Naeve GS, Sharma A, Lee AS. PMID: 1883619.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    155. Expression of the glucose-regulated proteins (GRP94 and GRP78) in differentiated and undifferentiated mouse embryonic cells and the use of the GRP78 promoter as an expression system in embryonic cells. Differentiation. 1990 Feb; 42(3):153-9. Kim SK, Kim YK, Lee AS. PMID: 1692794.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    156. The rat 78,000 dalton glucose-regulated protein (GRP78) as a precursor for the rat steroidogenesis-activator polypeptide (SAP): the SAP coding sequence is homologous with the terminal end of GRP78. Mol Endocrinol. 1989 Dec; 3(12):1944-52. Li XA, Warren DW, Gregoire J, Pedersen RC, Lee AS. PMID: 2628731.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    157. Transcriptional regulation of the gene encoding the 78-kD glucose-regulated protein GRP78 in mouse sertoli cells: binding of specific factor(s) to the GRP78 promoter. DNA. 1989 Jun; 8(5):301-10. Day AR, Lee AS. PMID: 2766928.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    158. Enhanced transcription of the 78,000-dalton glucose-regulated protein (GRP78) gene and association of GRP78 with immunoglobulin light chains in a nonsecreting B-cell myeloma line (NS-1). Mol Cell Biol. 1989 May; 9(5):2233-8. Nakaki T, Deans RJ, Lee AS. PMID: 2501663.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    159. Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors. Mol Cell Biol. 1989 May; 9(5):2153-62. Chang SC, Erwin AE, Lee AS. PMID: 2546060.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    160. Cooperative interactions between the GRP78 enhancer and promoter elements in hamster fibroblasts. Gene. 1989 Apr 15; 77(1):123-31. Kim YK, Lee AS. PMID: 2545535.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    161. Cell cycle regulation of H2b histone octamer DNA-binding activity in Chinese hamster lung fibroblasts. Mol Cell Biol. 1989 Feb; 9(2):869-73. Ito M, Sharma A, Lee AS, Maxson R. PMID: 2710129.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    162. Interaction of cellular factors related to the Jun oncoprotein with the promoter of a replication-dependent hamster histone H3.2 gene. Proc Natl Acad Sci U S A. 1989 Jan; 86(2):491-5. Sharma A, Bos TJ, Pekkala-Flagan A, Vogt PK, Lee AS. PMID: 2492109.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    163. Identity of the immunoglobulin heavy-chain-binding protein with the 78,000-dalton glucose-regulated protein and the role of posttranslational modifications in its binding function. Mol Cell Biol. 1988 Oct; 8(10):4250-6. Hendershot LM, Ting J, Lee AS. PMID: 3141786.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    164. Identification of highly conserved regulatory domains and protein-binding sites in the promoters of the rat and human genes encoding the stress-inducible 78-kilodalton glucose-regulated protein. Mol Cell Biol. 1988 Oct; 8(10):4579-84. Resendez E, Wooden SK, Lee AS. PMID: 3185564.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    165. The organization of the rat GRP78 gene and A23187-induced expression of fusion gene products targeted intracellularly. Exp Cell Res. 1988 Sep; 178(1):84-92. Wooden SK, Kapur RP, Lee AS. PMID: 3137085.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    166. Sequences contained within the promoter of the human thymidine kinase gene can direct cell-cycle regulation of heterologous fusion genes. Proc Natl Acad Sci U S A. 1988 Aug; 85(16):5894-8. Kim YK, Wells S, Lau YF, Lee AS. PMID: 3413063.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    167. Human gene encoding the 78,000-dalton glucose-regulated protein and its pseudogene: structure, conservation, and regulation. DNA. 1988 May; 7(4):275-86. Ting J, Lee AS. PMID: 2840249.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    168. Increased expression of the glucose-regulated gene encoding the Mr 78,000 glucose-regulated protein in chemically and radiation-transformed C3H 10T1/2 mouse embryo cells. Cancer Res. 1987 Dec 01; 47(23):6220-4. Patierno SR, Tuscano JM, Kim KS, Landolph JR, Lee AS. PMID: 2445468.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    169. Regulation of the glucose-regulated protein genes by beta-mercaptoethanol requires de novo protein synthesis and correlates with inhibition of protein glycosylation. J Cell Physiol. 1987 Dec; 133(3):553-9. Kim YK, Kim KS, Lee AS. PMID: 3693412.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    170. Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts. J Biol Chem. 1987 Sep 15; 262(26):12801-5. Drummond IA, Lee AS, Resendez E, Steinhardt RA. PMID: 3114264.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    171. Transcriptional activation of the glucose-regulated protein genes and their heterologous fusion genes by beta-mercaptoethanol. Mol Cell Biol. 1987 Aug; 7(8):2974-6. Kim YK, Lee AS. PMID: 3670303.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    172. Cell-cycle regulatory sequences in a hamster histone promoter and their interactions with cellular factors. Nature. 1987 Aug 27-Sep 2; 328(6133):823-7. Artishevsky A, Wooden S, Sharma A, Resendez E, Lee AS. PMID: 3627229.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    173. Rat gene encoding the 78-kDa glucose-regulated protein GRP78: its regulatory sequences and the effect of protein glycosylation on its expression. Proc Natl Acad Sci U S A. 1987 Feb; 84(3):680-4. Chang SC, Wooden SK, Nakaki T, Kim YK, Lin AY, Kung L, Attenello JW, Lee AS. PMID: 3468506.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    174. The nucleotide sequence encoding the hamster 78-kDa glucose-regulated protein (GRP78) and its conservation between hamster and rat. Gene. 1987; 55(1):147-52. Ting J, Wooden SK, Kriz R, Kelleher K, Kaufman RJ, Lee AS. PMID: 3623104.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    175. Coordinated regulation of a set of genes by glucose and calcium ionophores in mammalian cells. 1987; 12:20-23. Lee AS..
    176. Calcium ionophore A23187 as a regulator of gene expression in mammalian cells. J Cell Biol. 1986 Dec; 103(6 Pt 1):2145-52. Resendez E, Ting J, Kim KS, Wooden SK, Lee AS. PMID: 3097027.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    177. Enhanced synthesis of the glucose/calcium-regulated proteins in a hamster cell mutant deficient in transfer of oligosaccharide core to polypeptides. J Cell Physiol. 1986 Dec; 129(3):277-82. Lee AS, Wells S, Kim KS, Scheffler IE. PMID: 3782307.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    178. The effect of extracellular Ca2+ and temperature on the induction of the heat-shock and glucose-regulated proteins in hamster fibroblasts. Biochem Biophys Res Commun. 1986 Nov 14; 140(3):881-7. Kim KS, Lee AS. PMID: 3778489.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    179. Effect of E1A and E1B viral proteins on the expression of a calcium ionophore-inducible gene and its promoter. Nucleic Acids Res. 1986 Jun 25; 14(12):4911-21. Lin AY, Lee AS. PMID: 2941719.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    180. A calcium ionophore-inducible cellular promoter is highly active and has enhancerlike properties. Mol Cell Biol. 1986 Apr; 6(4):1235-43. Lin AY, Chang SC, Lee AS. PMID: 3023878.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    181. Methylation analysis of a plasmid containing a mammalian cell cycle regulatory sequence after transient transfection into the host cell. Biochem Biophys Res Commun. 1986 Mar 28; 135(3):942-9. Lee AS, Wells S, Delegeane AM. PMID: 3008749.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    182. Isolation of a mammalian sequence capable of conferring cell cycle regulation to a heterologous gene. Science. 1985 Nov 29; 230(4729):1061-3. Artishevsky A, Grafsky A, Lee AS. PMID: 4059922.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    183. Calcium ionophore A23187 induces expression of glucose-regulated genes and their heterologous fusion genes. Mol Cell Biol. 1985 Jun; 5(6):1212-9. Resendez E, Attenello JW, Grafsky A, Chang CS, Lee AS. PMID: 3929069.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    184. Use of a cell cycle mutant to delineate the critical period for the control of histone mRNA levels in the mammalian cell cycle. Mol Cell Biol. 1984 Nov; 4(11):2364-9. Artishevsky A, Delegeane AM, Lee AS. PMID: 6513920.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    185. Regulation of a hybrid gene by glucose and temperature in hamster fibroblasts. Science. 1984 Oct 12; 226(4671):187-90. Attenello JW, Lee AS. PMID: 6484570.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    186. Biochemical characterization of the 94- and 78-kilodalton glucose-regulated proteins in hamster fibroblasts. J Biol Chem. 1984 Apr 10; 259(7):4616-21. Lee AS, Bell J, Ting J. PMID: 6707023.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    187. Induction of two genes by glucose starvation in hamster fibroblasts. Proc Natl Acad Sci U S A. 1984 Feb; 81(4):988-92. Lin AY, Lee AS. PMID: 6583707.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    188. Polymerization of vector DNA after transfection into hamster fibroblast cells. Biochem Biophys Res Commun. 1983 Jan 27; 110(2):593-601. Wang ML, Lee AS. PMID: 6301457.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    189. Transcriptional regulation of two genes specifically induced by glucose starvation in a hamster mutant fibroblast cell line. J Biol Chem. 1983 Jan 10; 258(1):597-603. Lee AS, Delegeane AM, Baker V, Chow PC. PMID: 6294115.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    190. Characterization of a cell cycle mutant derived from hamster fibroblast: reversion analysis. J Cell Biol. 1982 Mar; 92(3):629-33. Scharff DJ, Delegeane AM, Lee AS. PMID: 7085753.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    191. Coupling of histone and DNA synthesis in the somatic cell cycle. Science. 1982 Jan 01; 215(4528):79-81. Delegeane AM, Lee AS. PMID: 7053561.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    192. Highly conserved glucose-regulated protein in hamster and chicken cells: preliminary characterization of its cDNA clone. Proc Natl Acad Sci U S A. 1981 Aug; 78(8):4922-5. Lee AS, Delegeane A, Scharff D. PMID: 6946438.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    193. The accumulation of three specific proteins related to glucose-regulated proteins in a temperature-sensitive hamster mutant cell line K12. J Cell Physiol. 1981 Jan; 106(1):119-25. Lee AS. PMID: 7204505.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    194. Four sizes of transcript produced by a single sea urchin gene expressed in early embryos. Proc Natl Acad Sci U S A. 1980 Jun; 77(6):3259-63. Lee AS, Thomas TL, Lev Z, Britten RJ, Davidson EH. PMID: 6997875.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    195. Developmental expression of two cloned sequences coding for rare sea urchin embryo messages. Dev Biol. 1980 May; 76(2):322-40. Lev Z, Thomas TL, Lee AS, Angerer RC, Britten RJ, Davidson EH. PMID: 7190106.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    196. Interspersion of short repetitive sequences studied in cloned sea urchin DNA fragments. Science. 1977 Apr 08; 196(4286):189-2. Lee AS, Britten RJ, Davidson EH. PMID: 847465.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    197. Clones of individual repetitive sequences from sea urchin DNA constructed with synthetic Eco RI sites. Science. 1977 Apr 08; 196(4286):197-200. Scheller RH, Thomas TL, Lee AS, Klein WH, Niles WD, Britten RJ, Davidson EH. PMID: 847467.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    198. Location of the 5-methylcytosine group on the bacteriophage phi X174 genome. J Virol. 1974 Oct; 14(4):872-7. Lee AS, Sinsheimer RL. PMID: 4609216.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    199. A continuous electroelution method for the recovery of DNA restriction enzyme fragments. Anal Biochem. 1974 Aug; 60(2):640-4. Lee AS, Sinsheimer RL. PMID: 4844577.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    200. A cleavage map of bacteriophage phiX174 genome. Proc Natl Acad Sci U S A. 1974 Jul; 71(7):2882-6. Lee AS, Sinsheimer RL. PMID: 4527604.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    201. Production of specific fragments of phi X174 replicative form DNA by a restriction enzyme from Haemophilus parainfluenzae, endonuclease HP. J Virol. 1973 Apr; 11(4):596-9. Johnson PH, Lee AS, Sinsheimer RL. PMID: 4700513.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
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