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Sebastian Brandhorst

Title(s)Research Assistant Professor of Gerontology
Address3715 McClintock Avenue, GER 329
University Park Campus
Los Angeles CA 90089-0191
Phone+1 213 740 1755
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fasting-mimicking diet and hormone therapy induce breast cancer regression. Nature. 2020 Jul; 583(7817):620-624. Caffa I, Spagnolo V, Vernieri C, Valdemarin F, Becherini P, Wei M, Brandhorst S, Zucal C, Driehuis E, Ferrando L, Piacente F, Tagliafico A, Cilli M, Mastracci L, Vellone VG, Piazza S, Cremonini AL, Gradaschi R, Mantero C, Passalacqua M, Ballestrero A, Zoppoli G, Cea M, Arrighi A, Odetti P, Monacelli F, Salvadori G, Cortellino S, Clevers H, De Braud F, Sukkar SG, Provenzani A, Longo VD, Nencioni A. PMID: 32669709.
      View in: PubMed   Mentions: 2     Fields:    
    2. The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan. Aging (Albany NY). 2020 Jun 23; 12(12):11185-11199. Yen K, Mehta HH, Kim SJ, Lue Y, Hoang J, Guerrero N, Port J, Bi Q, Navarrete G, Brandhorst S, Lewis KN, Wan J, Swerdloff R, Mattison JA, Buffenstein R, Breton CV, Wang C, Longo V, Atzmon G, Wallace D, Barzilai N, Cohen P. PMID: 32575074.
      View in: PubMed   Mentions:    Fields:    
    3. Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers. Nat Commun. 2020 05 11; 11(1):2332. Di Tano M, Raucci F, Vernieri C, Caffa I, Buono R, Fanti M, Brandhorst S, Curigliano G, Nencioni A, de Braud F, Longo VD. PMID: 32393788.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Assessing Insulin and Glucose Tolerance in the Aging Mouse. Methods Mol Biol. 2020; 2144:125-129. Buono R, Brandhorst S. PMID: 32410030.
      View in: PubMed   Mentions:    Fields:    
    5. Protein Quantity and Source, Fasting-Mimicking Diets, and Longevity. Adv Nutr. 2019 11 01; 10(Suppl_4):S340-S350. Brandhorst S, Longo VD. PMID: 31728501.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    6. Personalized Nutrition: Translating the Science of NutriGenomics Into Practice: Proceedings From the 2018 American College of Nutrition Meeting. J Am Coll Nutr. 2019 May-Jun; 38(4):287-301. Aruoma OI, Hausman-Cohen S, Pizano J, Schmidt MA, Minich DM, Joffe Y, Brandhorst S, Evans SJ, Brady DM. PMID: 31099726.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Dietary Restrictions and Nutrition in the Prevention and Treatment of Cardiovascular Disease. Circ Res. 2019 03 15; 124(6):952-965. Brandhorst S, Longo VD. PMID: 30870119.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    8. Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology. Cell Rep. 2019 03 05; 26(10):2704-2719.e6. Rangan P, Choi I, Wei M, Navarrete G, Guen E, Brandhorst S, Enyati N, Pasia G, Maesincee D, Ocon V, Abdulridha M, Longo VD. PMID: 30840892.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    9. Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans. Sci Rep. 2018 09 21; 8(1):14212. Yen K, Wan J, Mehta HH, Miller B, Christensen A, Levine ME, Salomon MP, Brandhorst S, Xiao J, Kim SJ, Navarrete G, Campo D, Harry GJ, Longo V, Pike CJ, Mack WJ, Hodis HN, Crimmins EM, Cohen P. PMID: 30242290.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    10. Chronic treatment with the mitochondrial peptide humanin prevents age-related myocardial fibrosis in mice. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1127-H1136. Qin Q, Mehta H, Yen K, Navarrete G, Brandhorst S, Wan J, Delrio S, Zhang X, Lerman LO, Cohen P, Lerman A. PMID: 30004252.
      View in: PubMed   Mentions:
    11. Correction: Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy. PLoS Biol. 2017 May; 15(5):e1002603. Di Biase S, Shim HS, Kim KH, Vinciguerra M, Rappa F, Wei M, Brandhorst S, Cappello F, Mirzaei H, Lee C, Longo VD. PMID: 28459830.
      View in: PubMed   Mentions: 2     Fields:    
    12. Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy. PLoS Biol. 2017 03; 15(3):e2001951. Di Biase S, Shim HS, Kim KH, Vinciguerra M, Rappa F, Wei M, Brandhorst S, Cappello F, Mirzaei H, Lee C, Longo VD. PMID: 28358805.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    13. Protective effects of short-term dietary restriction in surgical stress and chemotherapy. Ageing Res Rev. 2017 Oct; 39:68-77. Brandhorst S, Harputlugil E, Mitchell JR, Longo VD. PMID: 28216454.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    14. Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Sci Transl Med. 2017 02 15; 9(377). Wei M, Brandhorst S, Shelehchi M, Mirzaei H, Cheng CW, Budniak J, Groshen S, Mack WJ, Guen E, Di Biase S, Cohen P, Morgan TE, Dorff T, Hong K, Michalsen A, Laviano A, Longo VD. PMID: 28202779.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    15. Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice. Sci Rep. 2017 02 01; 7:40919. Lee AS, Brandhorst S, Rangel DF, Navarrete G, Cohen P, Longo VD, Chen J, Groshen S, Morgan TE, Dubeau L. PMID: 28145503.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    16. Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity. Cancer Cell. 2016 07 11; 30(1):136-146. Di Biase S, Lee C, Brandhorst S, Manes B, Buono R, Cheng CW, Cacciottolo M, Martin-Montalvo A, de Cabo R, Wei M, Morgan TE, Longo VD. PMID: 27411588.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    17. Safety and feasibility of fasting in combination with platinum-based chemotherapy. BMC Cancer. 2016 06 10; 16:360. Dorff TB, Groshen S, Garcia A, Shah M, Tsao-Wei D, Pham H, Cheng CW, Brandhorst S, Cohen P, Wei M, Longo V, Quinn DI. PMID: 27282289.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    18. A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms. Cell Rep. 2016 06 07; 15(10):2136-2146. Choi IY, Piccio L, Childress P, Bollman B, Ghosh A, Brandhorst S, Suarez J, Michalsen A, Cross AH, Morgan TE, Wei M, Paul F, Bock M, Longo VD. PMID: 27239035.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    19. Fasting and Caloric Restriction in Cancer Prevention and Treatment. Recent Results Cancer Res. 2016; 207:241-66. Brandhorst S, Longo VD. PMID: 27557543.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    20. A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan. Cell Metab. 2015 Jul 07; 22(1):86-99. Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan TE, Dorff TB, Longo VD. PMID: 26094889.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimals
    21. Starvation promotes REV1 SUMOylation and p53-dependent sensitization of melanoma and breast cancer cells. Cancer Res. 2015 Mar 15; 75(6):1056-67. Shim HS, Wei M, Brandhorst S, Longo VD. PMID: 25614517.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    22. Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 2014 Mar 04; 19(3):407-17. Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD. PMID: 24606898.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansAnimalsCells
    23. Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Exp Gerontol. 2013 Oct; 48(10):1120-8. Brandhorst S, Wei M, Hwang S, Morgan TE, Longo VD. PMID: 23454633.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    24. Fasting enhances the response of glioma to chemo- and radiotherapy. PLoS One. 2012; 7(9):e44603. Safdie F, Brandhorst S, Wei M, Wang W, Lee C, Hwang S, Conti PS, Chen TC, Longo VD. PMID: 22984531.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    25. Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med. 2012 Mar 07; 4(124):124ra27. Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Martin-Montalvo A, Pistoia V, Wei M, Hwang S, Merlino A, Emionite L, de Cabo R, Longo VD. PMID: 22323820.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
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