Changhan Lee, PhD

Title(s)Assistant Professor
SchoolSchool of Gerontology
Phone+1 213 740 1396
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee C, Kim KH, Cohen P. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radic Biol Med. 2016 11; 100:182-187. PMID: 27216708.
      View in: PubMed
    2. Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H, Hevener AL, de Cabo R, Cohen P. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metab. 2015 Mar 03; 21(3):443-54. PMID: 25738459; PMCID: PMC4350682.
    3. Lee C, Wan J, Miyazaki B, Fang Y, Guevara-Aguirre J, Yen K, Longo V, Bartke A, Cohen P. IGF-I regulates the age-dependent signaling peptide humanin. Aging Cell. 2014 Oct; 13(5):958-61. PMID: 25040290; PMCID: PMC4172517.
    4. Lee C, Peters V, Melefors O, Römling U. Draft Genome Sequence of Pseudomonas aeruginosa SG17M, an Environmental Isolate Belonging to Clone C, Prevalent in Patients and Aquatic Habitats. Genome Announc. 2014 Mar 20; 2(2). PMID: 24652978; PMCID: PMC3961725.
    5. Lee C, Kim I, Park C. Glyoxal detoxification in Escherichia coli K-12 by NADPH dependent aldo-keto reductases. J Microbiol. 2013 Aug; 51(4):527-30. PMID: 23990306.
      View in: PubMed
    6. Lee C, Shin J, Park C. Novel regulatory system nemRA-gloA for electrophile reduction in Escherichia coli K-12. Mol Microbiol. 2013 Apr; 88(2):395-412. PMID: 23506073.
      View in: PubMed
    7. Lee C, Park C. Mutations upregulating the flhDC operon of Escherichia coli K-12. J Microbiol. 2013 Feb; 51(1):140-4. PMID: 23456724.
      View in: PubMed
    8. Lee C, Yen K, Cohen P. Humanin: a harbinger of mitochondrial-derived peptides? Trends Endocrinol Metab. 2013 May; 24(5):222-8. PMID: 23402768; PMCID: PMC3641182.
    9. Yen K, Lee C, Mehta H, Cohen P. The emerging role of the mitochondrial-derived peptide humanin in stress resistance. J Mol Endocrinol. 2013 Feb; 50(1):R11-9. PMID: 23239898; PMCID: PMC3705736.
    10. Safdie F, Brandhorst S, Wei M, Wang W, Lee C, Hwang S, Conti PS, Chen TC, Longo VD. Fasting enhances the response of glioma to chemo- and radiotherapy. PLoS One. 2012; 7(9):e44603. PMID: 22984531; PMCID: PMC3439413.
    11. Lee C, Park C. Development of a suicidal vector-cloning system based on butanal susceptibility due to an expression of YqhD aldehyde reductase. J Microbiol. 2012 Apr; 50(2):249-55. PMID: 22538653.
      View in: PubMed
    12. Lee C, Raffaghello L, Longo VD. Starvation, detoxification, and multidrug resistance in cancer therapy. Drug Resist Updat. 2012 Feb-Apr; 15(1-2):114-22. PMID: 22391012; PMCID: PMC3573885.
    13. Kwon M, Lee J, Lee C, Park C. Genomic rearrangements leading to overexpression of aldo-keto reductase YafB of Escherichia coli confer resistance to glyoxal. J Bacteriol. 2012 Apr; 194(8):1979-88. PMID: 22328670; PMCID: PMC3318463.
    14. Lee C, Raffaghello L, Brandhorst S, Safdie FM, Bianchi G, Martin-Montalvo A, Pistoia V, Wei M, Hwang S, Merlino A, Emionite L, de Cabo R, Longo VD. Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med. 2012 Mar 07; 4(124):124ra27. PMID: 22323820; PMCID: PMC3608686.
    15. Lee C, Kim I, Lee J, Lee KL, Min B, Park C. Transcriptional activation of the aldehyde reductase YqhD by YqhC and its implication in glyoxal metabolism of Escherichia coli K-12. J Bacteriol. 2010 Aug; 192(16):4205-14. PMID: 20543070; PMCID: PMC2916428.
    16. Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E, Hwang D, Cohen P, Bianchi G, Longo VD. Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res. 2010 Feb 15; 70(4):1564-72. PMID: 20145127; PMCID: PMC2836202.
    17. Safdie FM, Dorff T, Quinn D, Fontana L, Wei M, Lee C, Cohen P, Longo VD. Fasting and cancer treatment in humans: A case series report. Aging (Albany NY). 2009 Dec 31; 1(12):988-1007. PMID: 20157582; PMCID: PMC2815756.
    18. Lee C, Lee SB. Surface growth on diluted lattices by a restricted solid-on-solid model. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Aug; 80(2 Pt 1):021134. PMID: 19792104.
      View in: PubMed
    19. Wozniak CE, Lee C, Hughes KT. T-POP array identifies EcnR and PefI-SrgD as novel regulators of flagellar gene expression. J Bacteriol. 2009 Mar; 191(5):1498-508. PMID: 19114490; PMCID: PMC2648201.
    20. Raffaghello L, Lee C, Safdie FM, Wei M, Madia F, Bianchi G, Longo VD. Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc Natl Acad Sci U S A. 2008 Jun 17; 105(24):8215-20. PMID: 18378900; PMCID: PMC2448817.
    21. Kim I, Kim J, Min B, Lee C, Park C. Screening of genes related to methylglyoxal susceptibility. J Microbiol. 2007 Aug; 45(4):339-43. PMID: 17846588.
      View in: PubMed
    22. Lee C, Wozniak C, Karlinsey JE, Hughes KT. Genomic screening for regulatory genes using the T-POP transposon. Methods Enzymol. 2007; 421:159-67. PMID: 17352922.
      View in: PubMed
    23. Lee C, Kim JM. Depinning transition of the Mullins-Herring equation with an external driving force and quenched random disorder. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Jan; 73(1 Pt 2):016140. PMID: 16486249.
      View in: PubMed