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Andrew Abba Stolz, MD

Title(s)Associate Professor of Medicine
AddressHMR 101
Health Sciences Campus
Los Angeles CA 90089-9091
Phone+1 323 442 2699
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    Other Positions
    Title(s)Associate Chair for Faculty Affairs for the Department of Medicine


    Collapse Biography 
    Collapse Awards and Honors
    American Liver Foundation1983  - 1985Postdoctoral Fellowship
    17th International Symposium of the Journal of Steroid Biochemistry & Molecular Biology2006Fabre Laboratories Best Poster

    Collapse Overview 
    Collapse Overview
    Dr. Stolz's major areas of research interest are mechanisms of protein mediated intracellular transport of bile acids in the liver, molecular characterization of Aldo-Keto Reductase supergene family members in rat, mouse and human, dysregulation of hormone catabolism in human breast and prostate cancers, and drug-induced liver injury, among others.

    Dr. Stolz earned his medical degree at Albert Einstein College of Medicine. He then performed his residency at Mt. Sinai Hospital, immediately followed by a Gastroenterology Fellowship at UCLA. Dr. Stolz has been a part of the Division of Gastrointestinal and Liver Diseases since 1990, earning tenure shortly after.

    Collapse Research 
    Collapse Research Activities and Funding
    USC-UCLA Drug-Induced Liver Injury (DILI) Clinical Center.
    NIH/NIDDK U01DK083020Sep 30, 2008 - Jun 30, 2023
    Role: Principal Investigator
    Targeting DHT Catabolism by AKR1Cs for Prostrate Cancer Prevention and Treatment.
    NIH/NCI R01CA122247Dec 3, 2007 - Nov 30, 2011
    Role: Principal Investigator
    MOLECULAR STUDIES OF A NOVEL BILE ACID BINDER
    NIH/NIDDK R01DK041014Jan 1, 1989 - Apr 30, 1999
    Role: Principal Investigator
    MOLECULAR STUDIES OF A KEY BILE ACID METABOLIZING ENZYME
    NIH/NIDDK R29DK041014Jan 1, 1989 - Jun 30, 1990
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. HLA-B*35:01 and Green Tea Induced Liver Injury. Hepatology. 2020 Sep 05. Hoofnagle JH, Bonkovsky HL, Phillips EJ, Li YJ, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Seeff LB, Serrano J, Stolz A, Tillmann HL, Vuppalanchi R, Navarro VJ. PMID: 32892374.
      View in: PubMed   Mentions:    Fields:    
    2. Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol-Related Liver Disease. Alcohol Clin Exp Res. 2020 05; 44(5):1061-1074. Marrero I, Maricic I, Morgan TR, Stolz AA, Schnabl B, Liu ZX, Tsukamoto H, Kumar V. PMID: 32154597.
      View in: PubMed   Mentions:    Fields:    
    3. HLA-B*14:01 and HLA-B*35:01 are associated with trimethoprim-sulfamethoxazole induced liver injury. Hepatology. 2020 Apr 09. Li YJ, Phillips E, Dellinger A, Nicoletti P, Schutte R, Li D, Ostrov DA, Fontana RJ, Watkins PB, Stolz A, Daly AK, Aithal GP, Barnhart H, Chalasani N. PMID: 32270503.
      View in: PubMed   Mentions:    Fields:    
    4. United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts. Toxicol Rep. 2020; 7:386-402. Oketch-Rabah HA, Roe AL, Rider CV, Bonkovsky HL, Giancaspro GI, Navarro V, Paine MF, Betz JM, Marles RJ, Casper S, Gurley B, Jordan SA, He K, Kapoor MP, Rao TP, Sherker AH, Fontana RJ, Rossi S, Vuppalanchi R, Seeff LB, Stolz A, Ahmad J, Koh C, Serrano J, Low Dog T, Ko R. PMID: 32140423.
      View in: PubMed   Mentions:
    5. Asparaginase-induced hepatotoxicity: rapid development of cholestasis and hepatic steatosis. Hepatol Int. 2019 Sep; 13(5):641-648. Kamal N, Koh C, Samala N, Fontana RJ, Stolz A, Durazo F, Hayashi PH, Phillips E, Wang T, Hoofnagle JH. PMID: 31392570.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury. Hepatol Commun. 2019 Aug; 3(8):1032-1035. Bonkovsky HL, Severson T, Nicoletti P, Barnhart H, Serrano J, Chalasani N, Fontana RJ, Watkins PB, Navarro V, Stolz A, Daly AK, Aithal GP, Odin J. PMID: 31388624.
      View in: PubMed   Mentions:
    7. The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled. Hepatol Commun. 2019 Jun; 3(6):792-794. Navarro V, Avula B, Khan I, Verma M, Seeff L, Serrano J, Stolz A, Fontana R, Ahmad J. PMID: 31168513.
      View in: PubMed   Mentions:
    8. Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors. Aliment Pharmacol Ther. 2019 05; 49(9):1195-1204. Stolz A, Navarro V, Hayashi PH, Fontana RJ, Barnhart HX, Gu J, Chalasani NP, Vega MM, Bonkovsky HL, Seeff LB, Serrano J, Avula B, Khan IA, Cirulli ET, Kleiner DE, Hoofnagle JH. PMID: 30934130.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    9. Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury. Dig Dis Sci. 2019 09; 64(9):2645-2652. Ahmad J, Reddy KR, Tillmann HL, Hayashi PH, Chalasani N, Fontana RJ, Navarro VJ, Stolz A, Barnhart H, Cloherty GA, Hoofnagle JH. PMID: 30927209.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group. PLoS One. 2019; 14(2):e0212394. Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PH, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J. PMID: 30742679.
      View in: PubMed   Mentions:    Fields:    
    11. A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury. Gastroenterology. 2019 05; 156(6):1707-1716.e2. Cirulli ET, Nicoletti P, Abramson K, Andrade RJ, Bjornsson ES, Chalasani N, Fontana RJ, Hallberg P, Li YJ, Lucena MI, Long N, Molokhia M, Nelson MR, Odin JA, Pirmohamed M, Rafnar T, Serrano J, Stefánsson K, Stolz A, Daly AK, Aithal GP, Watkins PB. PMID: 30664875.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    12. Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group. PLoS One. 2018; 13(10):e0206389. Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PJ, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J. PMID: 30359443.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. Sclerosing Cholangitis-Like Changes on Magnetic Resonance Cholangiography in Patients With Drug Induced Liver Injury. Clin Gastroenterol Hepatol. 2019 03; 17(4):789-790. Ahmad J, Rossi S, Rodgers SK, Ghabril M, Fontana RJ, Stolz A, Hayashi PH, Barnhart H, Kleiner DE, Bjornsson ES. PMID: 29966706.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Prediction of histologic alcoholic hepatitis based on clinical presentation limits the need for liver biopsy. Hepatol Commun. 2017 12; 1(10):1070-1084. Roth NC, Saberi B, Macklin J, Kanel G, French SW, Govindarajan S, Buzzanco AS, Stolz AA, Donovan JA, Kaplowitz N. PMID: 29404443.
      View in: PubMed   Mentions:
    15. Idiosyncratic Drug Induced Liver Injury in African-Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians. Am J Gastroenterol. 2017 Sep; 112(9):1382-1388. Chalasani N, Reddy KRK, Fontana RJ, Barnhart H, Gu J, Hayashi PH, Ahmad J, Stolz A, Navarro V, Hoofnagle JH. PMID: 28762375.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    16. Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B*35:02 as a risk factor. J Hepatol. 2017 07; 67(1):137-144. Urban TJ, Nicoletti P, Chalasani N, Serrano J, Stolz A, Daly AK, Aithal GP, Dillon J, Navarro V, Odin J, Barnhart H, Ostrov D, Long N, Cirulli ET, Watkins PB, Fontana RJ. PMID: 28323125.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    17. Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Gastroenterology. 2017 04; 152(5):1078-1089. Nicoletti P, Aithal GP, Bjornsson ES, Andrade RJ, Sawle A, Arrese M, Barnhart HX, Bondon-Guitton E, Hayashi PH, Bessone F, Carvajal A, Cascorbi I, Cirulli ET, Chalasani N, Conforti A, Coulthard SA, Daly MJ, Day CP, Dillon JF, Fontana RJ, Grove JI, Hallberg P, Hernández N, Ibáñez L, Kullak-Ublick GA, Laitinen T, Larrey D, Lucena MI, Maitland-van der Zee AH, Martin JH, Molokhia M, Pirmohamed M, Powell EE, Qin S, Serrano J, Stephens C, Stolz A, Wadelius M, Watkins PB, Floratos A, Shen Y, Nelson MR, Urban TJ, Daly AK. PMID: 28043905.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    18. Erratum to: Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series. Dig Dis Sci. 2016 12; 61(12):3638. Heidemann LA, Navarro VJ, Ahmad J, Hayashi PH, Stolz A, Kleiner DE, Fontana RJ. PMID: 27714508.
      View in: PubMed   Mentions: 1     Fields:    
    19. Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series. Dig Dis Sci. 2016 09; 61(9):2741-8. Heidemann LA, Navarro VJ, Ahmad J, Hayashi PH, Stolz A, Kleiner DE, Fontana RJ. PMID: 27142670.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    20. Liver injury from nonsteroidal anti-inflammatory drugs in the United States. Liver Int. 2016 Apr; 36(4):603-9. Schmeltzer PA, Kosinski AS, Kleiner DE, Hoofnagle JH, Stolz A, Fontana RJ, Russo MW. PMID: 26601797.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    21. Persistent liver biochemistry abnormalities are more common in older patients and those with cholestatic drug induced liver injury. Am J Gastroenterol. 2015 Oct; 110(10):1450-9. Fontana RJ, Hayashi PH, Barnhart H, Kleiner DE, Reddy KR, Chalasani N, Lee WM, Stolz A, Phillips T, Serrano J, Watkins PB. PMID: 26346867.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    22. Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study. Gastroenterology. 2015 Jun; 148(7):1340-52.e7. Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, Reddy KR, Watkins PB, Navarro V, Barnhart H, Gu J, Serrano J. PMID: 25754159.
      View in: PubMed   Mentions: 121     Fields:    Translation:Humans
    23. Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity. Clin Gastroenterol Hepatol. 2015 Sep; 13(9):1676-82.e1. Hayashi PH, Fontana RJ, Chalasani NP, Stolz AA, Talwalkar JA, Navarro VJ, Lee WM, Davern TJ, Kleiner DE, Gu J, Hoofnagle JH. PMID: 25724701.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    24. Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology. 2014 Oct; 60(4):1399-408. Navarro VJ, Barnhart H, Bonkovsky HL, Davern T, Fontana RJ, Grant L, Reddy KR, Seeff LB, Serrano J, Sherker AH, Stolz A, Talwalkar J, Vega M, Vuppalanchi R. PMID: 25043597.
      View in: PubMed   Mentions: 87     Fields:    Translation:Humans
    25. Clinical and histologic features of azithromycin-induced liver injury. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):369-376.e3. Martinez MA, Vuppalanchi R, Fontana RJ, Stolz A, Kleiner DE, Hayashi PH, Gu J, Hoofnagle JH, Chalasani N. PMID: 25111234.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    26. Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug-Induced Liver Injury Network (DILIN). Liver Int. 2015 May; 35(5):1623-32. Hayashi PH, Barnhart HX, Fontana RJ, Chalasani N, Davern TJ, Talwalkar JA, Reddy KR, Stolz AA, Hoofnagle JH, Rockey DC. PMID: 24661785.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    27. Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset. Gastroenterology. 2014 Jul; 147(1):96-108.e4. Fontana RJ, Hayashi PH, Gu J, Reddy KR, Barnhart H, Watkins PB, Serrano J, Lee WM, Chalasani N, Stolz A, Davern T, Talwakar JA. PMID: 24681128.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    28. Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance. PLoS One. 2013; 8(12):e81974. Steuerwald NM, Foureau DM, Norton HJ, Zhou J, Parsons JC, Chalasani N, Fontana RJ, Watkins PB, Lee WM, Reddy KR, Stolz A, Talwalkar J, Davern T, Saha D, Bell LN, Barnhart H, Gu J, Serrano J, Bonkovsky HL. PMID: 24386086.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    29. Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations. Hepatology. 2014 Feb; 59(2):661-70. Kleiner DE, Chalasani NP, Lee WM, Fontana RJ, Bonkovsky HL, Watkins PB, Hayashi PH, Davern TJ, Navarro V, Reddy R, Talwalkar JA, Stolz A, Gu J, Barnhart H, Hoofnagle JH. PMID: 24037963.
      View in: PubMed   Mentions: 75     Fields:    Translation:Humans
    30. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics. 2012 Nov; 22(11):784-95. Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe'er I, Serrano J, Bonkovsky H, Davern TJ, Lee WM, Navarro VJ, Talwalkar JA, Goldstein DB, Watkins PB. PMID: 22968431.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    31. AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes. Am J Perinatol. 2008 Oct; 25(9):577-82. Lee RH, Stanczyk FZ, Stolz A, Ji Q, Yang G, Goodwin TM. PMID: 18770491.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. 3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism. J Clin Endocrinol Metab. 2008 Apr; 93(4):1298-303. Steiner AZ, Chang L, Ji Q, Ookhtens M, Stolz A, Paulson RJ, Stanczyk FZ. PMID: 18252781.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Impaired dihydrotestosterone catabolism in human prostate cancer: critical role of AKR1C2 as a pre-receptor regulator of androgen receptor signaling. Cancer Res. 2007 Feb 01; 67(3):1361-9. Ji Q, Chang L, Stanczyk FZ, Ookhtens M, Sherrod A, Stolz A. PMID: 17283174.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    34. Induction of AKR1C2 by phase II inducers: identification of a distal consensus antioxidant response element regulated by NRF2. Mol Pharmacol. 2006 May; 69(5):1662-72. Lou H, Du S, Ji Q, Stolz A. PMID: 16478829.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    35. Localization and altered expression of AKR1C family members in human ovarian tissues. Mol Cell Probes. 2005 Aug; 19(4):261-6. Ji Q, Aoyama C, Chen PK, Stolz A, Liu P. PMID: 15979276.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    36. Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR. Mol Cell Endocrinol. 2005 Jan 14; 229(1-2):103-10. Ji Q, Liu PI, Elshimali Y, Stolz A. PMID: 15607534.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    37. Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling. Cancer Res. 2004 Oct 15; 64(20):7610-7. Ji Q, Aoyama C, Nien YD, Liu PI, Chen PK, Chang L, Stanczyk FZ, Stolz A. PMID: 15492289.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    38. Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1335-44. Lou H, Ookhtens M, Stolz A, Kaplowitz N. PMID: 12893631.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    39. Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism. Prostate. 2003 Mar 01; 54(4):275-89. Ji Q, Chang L, VanDenBerg D, Stanczyk FZ, Stolz A. PMID: 12539226.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    40. A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res. 2003 Mar; 44(3):503-11. Vergnes L, Phan J, Stolz A, Reue K. PMID: 12562828.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    41. An association between genetic polymorphisms in the ileal sodium-dependent bile acid transporter gene and the risk of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 2001 Sep; 10(9):931-6. Wang W, Xue S, Ingles SA, Chen Q, Diep AT, Frankl HD, Stolz A, Haile RW. PMID: 11535543.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    42. Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2. Exp Eye Res. 2001 Aug; 73(2):159-65. Kannan R, Stolz A, Ji Q, Prasad PD, Ganapathy V. PMID: 11446766.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    43. Rat and human bile acid binders are members of the monomeric reductase gene family. Adv Exp Med Biol. 1995; 372:269-80. Stolz A, Hammond L, Lou H. PMID: 7484388.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    44. Genomic organization and chromosomal localization of a novel human hepatic dihydrodiol dehydrogenase with high affinity bile acid binding. J Biol Chem. 1994 Mar 18; 269(11):8416-22. Lou H, Hammond L, Sharma V, Sparkes RS, Lusis AJ, Stolz A. PMID: 8132567.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    45. Identification and purification of a human liver cytosolic tocopherol binding protein. Protein Expr Purif. 1993 Oct; 4(5):382-9. Kuhlenkamp J, Ronk M, Yusin M, Stolz A, Kaplowitz N. PMID: 8251749.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    46. cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family. J Biol Chem. 1993 May 15; 268(14):10448-57. Stolz A, Hammond L, Lou H, Takikawa H, Ronk M, Shively JE. PMID: 8486699.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    47. Identification, purification, and immunochemical characterization of a tocopherol-binding protein in rat liver cytosol. J Lipid Res. 1992 Mar; 33(3):343-50. Yoshida H, Yusin M, Ren I, Kuhlenkamp J, Hirano T, Stolz A, Kaplowitz N. PMID: 1569384.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    48. Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family. J Biol Chem. 1991 Aug 15; 266(23):15253-7. Stolz A, Rahimi-Kiani M, Ameis D, Chan E, Ronk M, Shively JE. PMID: 1714456.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
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