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Refinement of Hy's Law using the Drug-Induced Liver Injury Network Database. Am J Gastroenterol. 2024 Oct 18.
Barritt AS, Hayashi PH, Stolz AA, Barnhart H, Hoofnagle JH, Drug-Induced Liver Injury Network (DILIN). PMID: 39422332.
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PubMed Mentions: Fields:
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Investigation of the Role of Chemical Analysis in Causality Assessment of Herbal and Dietary Supplement-Induced Liver Injury. Drug Saf. 2024 Oct 01.
Halegoua-DeMarzio D, Navarro VJ, Davis A, Ahmad J, Avula B, Barnhart H, Barritt AS, Bonkovsky HL, Chen VL, Choi G, Fontana RJ, Ghabril MS, Khan I, Koh C, Odin J, Rockey DC, Rostami H, Serrano J, Sherker AH, Stolz A, Tillmann HL, Vuppalanchi R, Drug-Induced Liver Injury Network. PMID: 39354283.
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PubMed Mentions: Fields:
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Genetic variants associated with immune-mediated liver injury from checkpoint inhibitors. Hepatol Commun. 2024 09 01; 8(9).
Fontana RJ, Li YJ, Chen V, Kleiner D, Stolz A, Odin J, Vuppalanchi R, Gu J, Dara L, Barnhart H, Drug-Induced Liver Injury Network. PMID: 39185906; PMCID: PMC11357698.
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PubMed Mentions: Fields:
Translation:
Humans
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The Liver Cirrhosis Network Cohort Study: Cirrhosis Definition, Study Population, and Endpoints. Am J Gastroenterol. 2024 Jul 17.
Tapper EB, Goldberg D, Parikh ND, Terrault NA, Welch N, Sharpton S, Hameed B, Khalili M, Stolz A, Verna EC, Brown RS, Sanyal AJ, VanWagner L, Ladner DP, Moylan CA, Diehl AM, Jones PD, Loomba R, Dasarathy S, Simonetto DA, Shah VH, Bajaj JS, LCN Study Group. PMID: 39018024.
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PubMed Mentions:
1 Fields:
-
Clinical characteristics and HLA associations of azithromycin-induced liver injury. Aliment Pharmacol Ther. 2024 Sep; 60(6):787-795.
Conlon C, Li YJ, Ahmad J, Barnhart H, Fontana RJ, Ghabril M, Hayashi PH, Kleiner DE, Lee WM, Navarro V, Odin JA, Phillips EJ, Stolz A, Vuppalanchi R, Halegoua-DeMarzio D, Drug-Induced Liver Injury Network (DILIN). PMID: 38988034.
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PubMed Mentions: Fields:
Translation:
Humans
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Characterisation of an outbreak of acute liver injury after ingestion of plant-based food supplement. Aliment Pharmacol Ther. 2024 Aug; 60(4):479-483.
Choi G, Ahmad J, Navarro V, Thung S, Khan I, Avula B, Barnhart H, Stolz A, Drug-Induced Liver Injury Network. PMID: 38874448.
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PubMed Mentions: Fields:
Translation:
HumansPHPublic Health
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Anabolic steroid-associated liver injury. Clin Liver Dis (Hoboken). 2024 Jan-Jun; 23(1):e0196.
Dukewich M, Stolz AA. PMID: 38872787; PMCID: PMC11168845.
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Steroid responsiveness in alcohol-associated hepatitis is linked to glucocorticoid metabolism, mitochondrial repair, and heat shock proteins. Hepatol Commun. 2024 03 01; 8(3).
Hardesty J, Hawthorne M, Day L, Warner J, Warner D, Gritsenko M, Asghar A, Stolz A, Morgan T, McClain C, Jacobs J, Kirpich IA. PMID: 38437061; PMCID: PMC10914234.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Identification of integrated proteomics and transcriptomics signature of alcohol-associated liver disease using machine learning. PLOS Digit Health. 2024 Feb; 3(2):e0000447.
Listopad S, Magnan C, Day LZ, Asghar A, Stolz A, Tayek JA, Liu ZX, Jacobs JM, Morgan TR, Norden-Krichmar TM. PMID: 38335183; PMCID: PMC10857706.
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PubMed Mentions:
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Identification of Reduced ERAP2 Expression and a Novel HLA Allele as Components of a Risk Score for Susceptibility to Liver Injury Due to Amoxicillin-Clavulanate. Gastroenterology. 2023 03; 164(3):454-466.
Nicoletti P, Dellinger A, Li YJ, Barnhart HX, Chalasani N, Fontana RJ, Odin JA, Serrano J, Stolz A, Etheridge AS, Innocenti F, Govaere O, Grove JI, Stephens C, Aithal GP, Andrade RJ, Bjornsson ES, Daly AK, Lucena MI, Watkins PB, Drug-Induced Liver Injury Network (DILIN), International Drug-Induced Liver Injury Consortium (iDILIC), Prospective European Drug-Induced Liver Injury (Pro-Euro DILI) Investigators. PMID: 36496055; PMCID: PMC9974860.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Naltrexone for alcohol use disorder: Hepatic safety in patients with and without liver disease. Hepatol Commun. 2022 12; 6(12):3433-3442.
Ayyala D, Bottyan T, Tien C, Pimienta M, Yoo J, Stager K, Gonzalez JL, Stolz A, Dodge JL, Terrault NA, Han H. PMID: 36281979; PMCID: PMC9701476.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Liver Injury Associated with Turmeric-A Growing Problem: Ten Cases from the Drug-Induced Liver Injury Network [DILIN]. Am J Med. 2023 02; 136(2):200-206.
Halegoua-DeMarzio D, Navarro V, Ahmad J, Avula B, Barnhart H, Barritt AS, Bonkovsky HL, Fontana RJ, Ghabril MS, Hoofnagle JH, Khan IA, Kleiner DE, Phillips E, Stolz A, Vuppalanchi R. PMID: 36252717; PMCID: PMC9892270.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis. Am J Pathol. 2022 12; 192(12):1658-1669.
Argemi J, Kedia K, Gritsenko MA, Clemente-Sanchez A, Asghar A, Herranz JM, Liu ZX, Atkinson SR, Smith RD, Norden-Krichmar TM, Day LZ, Stolz A, Tayek JA, Bataller R, Morgan TR, Jacobs JM, Southern California Alcoholic Hepatitis Consortium and the InTeam Consortium. PMID: 36243044; PMCID: PMC9765311.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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A phase II, multicenter, open-label, randomized trial of pegfilgrastim for patients with alcohol-associated hepatitis. EClinicalMedicine. 2022 Dec; 54:101689.
Tayek JA, Stolz AA, Nguyen DV, Fleischman MW, Donovan JA, Alcorn JM, Chao DC, Asghar A, Morgan TR, Southern California Alcoholic Hepatitis (SCAH) Consortium. PMID: 36267499; PMCID: PMC9576807.
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PubMed Mentions:
4
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Differentiating between liver diseases by applying multiclass machine learning approaches to transcriptomics of liver tissue or blood-based samples. JHEP Rep. 2022 Oct; 4(10):100560.
Listopad S, Magnan C, Asghar A, Stolz A, Tayek JA, Liu ZX, Morgan TR, Norden-Krichmar TM. PMID: 36119721; PMCID: PMC9472076.
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PubMed Mentions:
3
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Newly identified genetic variants associated with idiosyncratic drug-induced liver injury. Curr Opin Gastroenterol. 2022 05 01; 38(3):230-238.
Stolz A. PMID: 35645018.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Hepatic Protein and Phosphoprotein Signatures of Alcohol-Associated Cirrhosis and Hepatitis. Am J Pathol. 2022 07; 192(7):1066-1082.
Hardesty J, Day L, Warner J, Warner D, Gritsenko M, Asghar A, Stolz A, Morgan T, McClain C, Jacobs J, Kirpich I. PMID: 35490715; PMCID: PMC9253914.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Garcinia cambogia, Either Alone or in Combination With Green Tea, Causes Moderate to Severe Liver Injury. Clin Gastroenterol Hepatol. 2022 06; 20(6):e1416-e1425.
Vuppalanchi R, Bonkovsky HL, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Phillips EJ, Li YJ, Serrano J, Stolz A, Tillmann HL, Seeff LB, Hoofnagle JH, Navarro VJ, Drug-Induced Liver Injury Network. PMID: 34400337; PMCID: PMC9004424.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
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HLA-B*35:01 and Green Tea-Induced Liver Injury. Hepatology. 2021 06; 73(6):2484-2493.
Hoofnagle JH, Bonkovsky HL, Phillips EJ, Li YJ, Ahmad J, Barnhart H, Durazo F, Fontana RJ, Gu J, Khan I, Kleiner DE, Koh C, Rockey DC, Seeff LB, Serrano J, Stolz A, Tillmann HL, Vuppalanchi R, Navarro VJ, Drug-Induced Liver Injury Network. PMID: 32892374; PMCID: PMC8052949.
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PubMed Mentions:
32 Fields:
Translation:
Humans
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Inhibition of Estrogen-Related Receptor α Blocks Liver Steatosis and Steatohepatitis and Attenuates Triglyceride Biosynthesis. Am J Pathol. 2021 07; 191(7):1240-1254.
Chen CY, Li Y, Zeng N, He L, Zhang X, Tu T, Tang Q, Alba M, Mir S, Stiles EX, Hong H, Cadenas E, Stolz AA, Li G, Stiles BL. PMID: 33894178; PMCID: PMC8261472.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Human Leukocyte Antigen B*14:01 and B*35:01 Are Associated With Trimethoprim-Sulfamethoxazole Induced Liver Injury. Hepatology. 2021 01; 73(1):268-281.
Li YJ, Phillips EJ, Dellinger A, Nicoletti P, Schutte R, Li D, Ostrov DA, Fontana RJ, Watkins PB, Stolz A, Daly AK, Aithal GP, Barnhart H, Chalasani N, Drug-induced Liver Injury Network. PMID: 32270503; PMCID: PMC7544638.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol-Related Liver Disease. Alcohol Clin Exp Res. 2020 05; 44(5):1061-1074.
Marrero I, Maricic I, Morgan TR, Stolz AA, Schnabl B, Liu ZX, Tsukamoto H, Kumar V. PMID: 32154597; PMCID: PMC7211132.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts. Toxicol Rep. 2020; 7:386-402.
Oketch-Rabah HA, Roe AL, Rider CV, Bonkovsky HL, Giancaspro GI, Navarro V, Paine MF, Betz JM, Marles RJ, Casper S, Gurley B, Jordan SA, He K, Kapoor MP, Rao TP, Sherker AH, Fontana RJ, Rossi S, Vuppalanchi R, Seeff LB, Stolz A, Ahmad J, Koh C, Serrano J, Low Dog T, Ko R. PMID: 32140423; PMCID: PMC7044683.
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PubMed Mentions:
51
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Asparaginase-induced hepatotoxicity: rapid development of cholestasis and hepatic steatosis. Hepatol Int. 2019 Sep; 13(5):641-648.
Kamal N, Koh C, Samala N, Fontana RJ, Stolz A, Durazo F, Hayashi PH, Phillips E, Wang T, Hoofnagle JH, Drug-Induced Liver Injury Network. PMID: 31392570; PMCID: PMC7226930.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury. Hepatol Commun. 2019 Aug; 3(8):1032-1035.
Bonkovsky HL, Severson T, Nicoletti P, Barnhart H, Serrano J, Chalasani N, Fontana RJ, Watkins PB, Navarro V, Stolz A, Daly AK, Aithal GP, Odin J, US DILIN Investigators. PMID: 31388624; PMCID: PMC6671782.
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PubMed Mentions:
2 Fields:
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The Contents of Herbal and Dietary Supplements Implicated in Liver Injury in the United States Are Frequently Mislabeled. Hepatol Commun. 2019 Jun; 3(6):792-794.
Navarro V, Avula B, Khan I, Verma M, Seeff L, Serrano J, Stolz A, Fontana R, Ahmad J. PMID: 31168513; PMCID: PMC6545864.
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PubMed Mentions:
13 Fields:
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Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors. Aliment Pharmacol Ther. 2019 05; 49(9):1195-1204.
Stolz A, Navarro V, Hayashi PH, Fontana RJ, Barnhart HX, Gu J, Chalasani NP, Vega MM, Bonkovsky HL, Seeff LB, Serrano J, Avula B, Khan IA, Cirulli ET, Kleiner DE, Hoofnagle JH, DILIN Investigators. PMID: 30934130; PMCID: PMC6682544.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury. Dig Dis Sci. 2019 09; 64(9):2645-2652.
Ahmad J, Reddy KR, Tillmann HL, Hayashi PH, Chalasani N, Fontana RJ, Navarro VJ, Stolz A, Barnhart H, Cloherty GA, Hoofnagle JH. PMID: 30927209; PMCID: PMC6706305.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Correction: Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group. PLoS One. 2019; 14(2):e0212394.
Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PH, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J, US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group. PMID: 30742679; PMCID: PMC6370229.
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PubMed Mentions:
2 Fields:
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A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury. Gastroenterology. 2019 05; 156(6):1707-1716.e2.
Cirulli ET, Nicoletti P, Abramson K, Andrade RJ, Bjornsson ES, Chalasani N, Fontana RJ, Hallberg P, Li YJ, Lucena MI, Long N, Molokhia M, Nelson MR, Odin JA, Pirmohamed M, Rafnar T, Serrano J, Stefánsson K, Stolz A, Daly AK, Aithal GP, Watkins PB, Drug-Induced Liver Injury Network (DILIN) investigators, International DILI consortium (iDILIC). PMID: 30664875; PMCID: PMC6511989.
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PubMed Mentions:
44 Fields:
Translation:
Humans
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Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group. PLoS One. 2018; 13(10):e0206389.
Bonkovsky HL, Barnhart HX, Foureau DM, Steuerwald N, Lee WM, Gu J, Fontana RJ, Hayashi PJ, Chalasani N, Navarro VM, Odin J, Stolz A, Watkins PB, Serrano J, US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group. PMID: 30359443; PMCID: PMC6201986.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Sclerosing Cholangitis-Like Changes on Magnetic Resonance Cholangiography in Patients With Drug Induced Liver Injury. Clin Gastroenterol Hepatol. 2019 03; 17(4):789-790.
Ahmad J, Rossi S, Rodgers SK, Ghabril M, Fontana RJ, Stolz A, Hayashi PH, Barnhart H, Kleiner DE, Bjornsson ES. PMID: 29966706; PMCID: PMC6311440.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
Prediction of histologic alcoholic hepatitis based on clinical presentation limits the need for liver biopsy. Hepatol Commun. 2017 12; 1(10):1070-1084.
Roth NC, Saberi B, Macklin J, Kanel G, French SW, Govindarajan S, Buzzanco AS, Stolz AA, Donovan JA, Kaplowitz N. PMID: 29404443; PMCID: PMC5721404.
View in:
PubMed Mentions:
9 Fields:
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Idiosyncratic Drug Induced Liver Injury in African-Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians. Am J Gastroenterol. 2017 Sep; 112(9):1382-1388.
Chalasani N, Reddy KRK, Fontana RJ, Barnhart H, Gu J, Hayashi PH, Ahmad J, Stolz A, Navarro V, Hoofnagle JH. PMID: 28762375; PMCID: PMC5667647.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor. J Hepatol. 2017 07; 67(1):137-144.
Urban TJ, Nicoletti P, Chalasani N, Serrano J, Stolz A, Daly AK, Aithal GP, Dillon J, Navarro V, Odin J, Barnhart H, Ostrov D, Long N, Cirulli ET, Watkins PB, Fontana RJ, Drug-Induced Liver Injury Network (DILIN), Pharmacogenetics of Drug-Induced Liver Injury group (DILIGEN), International Serious Adverse Events Consortium (iSAEC). PMID: 28323125; PMCID: PMC5634615.
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PubMed Mentions:
51 Fields:
Translation:
Humans
-
Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study. Gastroenterology. 2017 04; 152(5):1078-1089.
Nicoletti P, Aithal GP, Bjornsson ES, Andrade RJ, Sawle A, Arrese M, Barnhart HX, Bondon-Guitton E, Hayashi PH, Bessone F, Carvajal A, Cascorbi I, Cirulli ET, Chalasani N, Conforti A, Coulthard SA, Daly MJ, Day CP, Dillon JF, Fontana RJ, Grove JI, Hallberg P, Hernández N, Ibáñez L, Kullak-Ublick GA, Laitinen T, Larrey D, Lucena MI, Maitland-van der Zee AH, Martin JH, Molokhia M, Pirmohamed M, Powell EE, Qin S, Serrano J, Stephens C, Stolz A, Wadelius M, Watkins PB, Floratos A, Shen Y, Nelson MR, Urban TJ, Daly AK, International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, . PMID: 28043905; PMCID: PMC5367948.
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PubMed Mentions:
88 Fields:
Translation:
HumansCells
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Erratum to: Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series. Dig Dis Sci. 2016 12; 61(12):3638.
Heidemann LA, Navarro VJ, Ahmad J, Hayashi PH, Stolz A, Kleiner DE, Fontana RJ. PMID: 27714508.
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PubMed Mentions: Fields:
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Severe Acute Hepatocellular Injury Attributed to OxyELITE Pro: A Case Series. Dig Dis Sci. 2016 09; 61(9):2741-8.
Heidemann LA, Navarro VJ, Ahmad J, Hayashi PH, Stolz A, Kleiner DE, Fontana RJ. PMID: 27142670; PMCID: PMC4982804.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Liver injury from nonsteroidal anti-inflammatory drugs in the United States. Liver Int. 2016 Apr; 36(4):603-9.
Schmeltzer PA, Kosinski AS, Kleiner DE, Hoofnagle JH, Stolz A, Fontana RJ, Russo MW, Drug-Induced Liver Injury Network (DILIN). PMID: 26601797; PMCID: PMC5035108.
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PubMed Mentions:
21 Fields:
Translation:
Humans
-
Persistent liver biochemistry abnormalities are more common in older patients and those with cholestatic drug induced liver injury. Am J Gastroenterol. 2015 Oct; 110(10):1450-9.
Fontana RJ, Hayashi PH, Barnhart H, Kleiner DE, Reddy KR, Chalasani N, Lee WM, Stolz A, Phillips T, Serrano J, Watkins PB, DILIN Investigators. PMID: 26346867; PMCID: PMC4784423.
View in:
PubMed Mentions:
32 Fields:
Translation:
Humans
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Comparative analysis of portal hepatic infiltrating leucocytes in acute drug-induced liver injury, idiopathic autoimmune and viral hepatitis. Clin Exp Immunol. 2015 Apr; 180(1):40-51.
Foureau DM, Walling TL, Maddukuri V, Anderson W, Culbreath K, Kleiner DE, Ahrens WA, Jacobs C, Watkins PB, Fontana RJ, Chalasani N, Talwalkar J, Lee WM, Stolz A, Serrano J, Bonkovsky HL. PMID: 25418487; PMCID: PMC4367092.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study. Gastroenterology. 2015 Jun; 148(7):1340-52.e7.
Chalasani N, Bonkovsky HL, Fontana R, Lee W, Stolz A, Talwalkar J, Reddy KR, Watkins PB, Navarro V, Barnhart H, Gu J, Serrano J, United States Drug Induced Liver Injury Network. PMID: 25754159; PMCID: PMC4446235.
View in:
PubMed Mentions:
314 Fields:
Translation:
Humans
-
Under-reporting and Poor Adherence to Monitoring Guidelines for Severe Cases of Isoniazid Hepatotoxicity. Clin Gastroenterol Hepatol. 2015 Sep; 13(9):1676-82.e1.
Hayashi PH, Fontana RJ, Chalasani NP, Stolz AA, Talwalkar JA, Navarro VJ, Lee WM, Davern TJ, Kleiner DE, Gu J, Hoofnagle JH, US Drug-Induced Liver Injury Network Investigators. PMID: 25724701; PMCID: PMC4653068.
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PubMed Mentions:
19 Fields:
Translation:
Humans
-
Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network. Hepatology. 2014 Oct; 60(4):1399-408.
Navarro VJ, Barnhart H, Bonkovsky HL, Davern T, Fontana RJ, Grant L, Reddy KR, Seeff LB, Serrano J, Sherker AH, Stolz A, Talwalkar J, Vega M, Vuppalanchi R. PMID: 25043597; PMCID: PMC4293199.
View in:
PubMed Mentions:
141 Fields:
Translation:
Humans
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Clinical and histologic features of azithromycin-induced liver injury. Clin Gastroenterol Hepatol. 2015 Feb; 13(2):369-376.e3.
Martinez MA, Vuppalanchi R, Fontana RJ, Stolz A, Kleiner DE, Hayashi PH, Gu J, Hoofnagle JH, Chalasani N. PMID: 25111234; PMCID: PMC4321982.
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PubMed Mentions:
58 Fields:
Translation:
Humans
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Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug-Induced Liver Injury Network (DILIN). Liver Int. 2015 May; 35(5):1623-32.
Hayashi PH, Barnhart HX, Fontana RJ, Chalasani N, Davern TJ, Talwalkar JA, Reddy KR, Stolz AA, Hoofnagle JH, Rockey DC. PMID: 24661785; PMCID: PMC4305346.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset. Gastroenterology. 2014 Jul; 147(1):96-108.e4.
Fontana RJ, Hayashi PH, Gu J, Reddy KR, Barnhart H, Watkins PB, Serrano J, Lee WM, Chalasani N, Stolz A, Davern T, Talwakar JA, DILIN Network. PMID: 24681128; PMCID: PMC4285559.
View in:
PubMed Mentions:
86 Fields:
Translation:
Humans
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Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance. PLoS One. 2013; 8(12):e81974.
Steuerwald NM, Foureau DM, Norton HJ, Zhou J, Parsons JC, Chalasani N, Fontana RJ, Watkins PB, Lee WM, Reddy KR, Stolz A, Talwalkar J, Davern T, Saha D, Bell LN, Barnhart H, Gu J, Serrano J, Bonkovsky HL. PMID: 24386086; PMCID: PMC3873930.
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PubMed Mentions:
30 Fields:
Translation:
Humans
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Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations. Hepatology. 2014 Feb; 59(2):661-70.
Kleiner DE, Chalasani NP, Lee WM, Fontana RJ, Bonkovsky HL, Watkins PB, Hayashi PH, Davern TJ, Navarro V, Reddy R, Talwalkar JA, Stolz A, Gu J, Barnhart H, Hoofnagle JH, Drug-Induced Liver Injury Network (DILIN). PMID: 24037963; PMCID: PMC3946736.
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PubMed Mentions:
148 Fields:
Translation:
Humans
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Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics. 2012 Nov; 22(11):784-95.
Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe'er I, Serrano J, Bonkovsky H, Davern TJ, Lee WM, Navarro VJ, Talwalkar JA, Goldstein DB, Watkins PB, Drug-Induced Liver Injury Network, DILIGEN, EUDRAGENE, Spanish DILI Registry, International Serious Adverse Events Consortium. PMID: 22968431; PMCID: PMC3636716.
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PubMed Mentions:
36 Fields:
Translation:
Humans
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Superallowed Gamow-Teller decay of the doubly magic nucleus 100Sn. Nature. 2012 Jun 20; 486(7403):341-5.
Hinke CB, Böhmer M, Boutachkov P, Faestermann T, Geissel H, Gerl J, Gernhäuser R, Górska M, Gottardo A, Grawe H, Grebosz JL, Krücken R, Kurz N, Liu Z, Maier L, Nowacki F, Pietri S, Podolyák Z, Sieja K, Steiger K, Straub K, Weick H, Wollersheim HJ, Woods PJ, Al-Dahan N, Alkhomashi N, Ataç A, Blazhev A, Braun NF, Celikovic IT, Davinson T, Dillmann I, Domingo-Pardo C, Doornenbal PC, de France G, Farrelly GF, Farinon F, Goel N, Habermann TC, Hoischen R, Janik R, Karny M, Kaskas A, Kojouharov IM, Kröll T, Litvinov Y, Myalski S, Nebel F, Nishimura S, Nociforo C, Nyberg J, Parikh AR, Procházka A, Regan PH, Rigollet C, Schaffner H, Scheidenberger C, Schwertel S, Söderström PA, Steer SJ, Stolz A, Strmen P. PMID: 22722192.
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PubMed Mentions:
4 Fields:
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AKR1C1 and SRD5A1 messenger RNA expression at term in the human myometrium and chorioamniotic membranes. Am J Perinatol. 2008 Oct; 25(9):577-82.
Lee RH, Stanczyk FZ, Stolz A, Ji Q, Yang G, Goodwin TM. PMID: 18770491.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism. J Clin Endocrinol Metab. 2008 Apr; 93(4):1298-303.
Steiner AZ, Chang L, Ji Q, Ookhtens M, Stolz A, Paulson RJ, Stanczyk FZ. PMID: 18252781; PMCID: PMC2291485.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Impaired dihydrotestosterone catabolism in human prostate cancer: critical role of AKR1C2 as a pre-receptor regulator of androgen receptor signaling. Cancer Res. 2007 Feb 01; 67(3):1361-9.
Ji Q, Chang L, Stanczyk FZ, Ookhtens M, Sherrod A, Stolz A. PMID: 17283174.
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PubMed Mentions:
27 Fields:
Translation:
HumansCells
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Induction of AKR1C2 by phase II inducers: identification of a distal consensus antioxidant response element regulated by NRF2. Mol Pharmacol. 2006 May; 69(5):1662-72.
Lou H, Du S, Ji Q, Stolz A. PMID: 16478829.
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PubMed Mentions:
36 Fields:
Translation:
HumansCells
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Localization and altered expression of AKR1C family members in human ovarian tissues. Mol Cell Probes. 2005 Aug; 19(4):261-6.
Ji Q, Aoyama C, Chen PK, Stolz A, Liu P. PMID: 15979276.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR. Mol Cell Endocrinol. 2005 Jan 14; 229(1-2):103-10.
Ji Q, Liu PI, Elshimali Y, Stolz A. PMID: 15607534.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Selective loss of AKR1C1 and AKR1C2 in breast cancer and their potential effect on progesterone signaling. Cancer Res. 2004 Oct 15; 64(20):7610-7.
Ji Q, Aoyama C, Nien YD, Liu PI, Chen PK, Chang L, Stanczyk FZ, Stolz A. PMID: 15492289.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1335-44.
Lou H, Ookhtens M, Stolz A, Kaplowitz N. PMID: 12893631.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism. Prostate. 2003 Mar 01; 54(4):275-89.
Ji Q, Chang L, VanDenBerg D, Stanczyk FZ, Stolz A. PMID: 12539226.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res. 2003 Mar; 44(3):503-11.
Vergnes L, Phan J, Stolz A, Reue K. PMID: 12562828.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Differential modulation of cellular death and survival pathways by conjugated bile acids. BMC Biochem. 2001; 2:11.
Torchia EC, Stolz A, Agellon LB. PMID: 11707155; PMCID: PMC59694.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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An association between genetic polymorphisms in the ileal sodium-dependent bile acid transporter gene and the risk of colorectal adenomas. Cancer Epidemiol Biomarkers Prev. 2001 Sep; 10(9):931-6.
Wang W, Xue S, Ingles SA, Chen Q, Diep AT, Frankl HD, Stolz A, Haile RW. PMID: 11535543.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2. Exp Eye Res. 2001 Aug; 73(2):159-65.
Kannan R, Stolz A, Ji Q, Prasad PD, Ganapathy V. PMID: 11446766.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Purification and characterization of a salicylate hydroxylase involved in 1-hydroxy-2-naphthoic acid hydroxylation from the naphthalene and phenanthrene-degrading bacterial strain Pseudomonas putida BS202-P1. Biodegradation. 2001; 12(3):179-88.
Balashova NV, Stolz A, Knackmuss HJ, Kosheleva IA, Naumov AV, Boronin AM. PMID: 11826899.
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PubMed Mentions:
18 Fields:
Translation:
CellsPHPublic Health
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Bile acid transport. Gastroenterol Clin North Am. 1999 Mar; 28(1):27-58.
Bahar RJ, Stolz A. PMID: 10198777.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis. Gastroenterology. 1996 Jan; 110(1):199-209.
Gartung C, Ananthanarayanan M, Rahman MA, Schuele S, Nundy S, Soroka CJ, Stolz A, Suchy FJ, Boyer JL. PMID: 8536857.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Characterization of a 2,3-dihydroxybiphenyl dioxygenase from the naphthalenesulfonate-degrading bacterium strain BN6. J Bacteriol. 1995 Oct; 177(20):5865-71.
Heiss G, Stolz A, Kuhm AE, Müller C, Klein J, Altenbuchner J, Knackmuss HJ. PMID: 7592336; PMCID: PMC177411.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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Rat and human bile acid binders are members of the monomeric reductase gene family. Adv Exp Med Biol. 1995; 372:269-80.
Stolz A, Hammond L, Lou H. PMID: 7484388.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Distribution of 3 alpha-hydroxysteroid dehydrogenase (bile acid binder) in rat small intestine: comparison with glutathione S-transferase subunits. J Gastroenterol. 1994 Apr; 29(2):115-9.
Yamamuro W, Stolz A, Takikawa H, Sugimoto M, Kaplowitz N. PMID: 8012502.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Genomic organization and chromosomal localization of a novel human hepatic dihydrodiol dehydrogenase with high affinity bile acid binding. J Biol Chem. 1994 Mar 18; 269(11):8416-22.
Lou H, Hammond L, Sharma V, Sparkes RS, Lusis AJ, Stolz A. PMID: 8132567.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Regulation of rat hepatic 3 alpha-hydroxysteroid dehydrogenase in vivo and in primary cultures of rat hepatocytes. J Lipid Res. 1994 Feb; 35(2):239-47.
Stravitz RT, Vlahcevic ZR, Pandak WM, Stolz A, Hylemon PB. PMID: 8169527.
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Translation:
AnimalsCells
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Identification and purification of a human liver cytosolic tocopherol binding protein. Protein Expr Purif. 1993 Oct; 4(5):382-9.
Kuhlenkamp J, Ronk M, Yusin M, Stolz A, Kaplowitz N. PMID: 8251749.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family. J Biol Chem. 1993 May 15; 268(14):10448-57.
Stolz A, Hammond L, Lou H, Takikawa H, Ronk M, Shively JE. PMID: 8486699.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Identification, purification, and immunochemical characterization of a tocopherol-binding protein in rat liver cytosol. J Lipid Res. 1992 Mar; 33(3):343-50.
Yoshida H, Yusin M, Ren I, Kuhlenkamp J, Hirano T, Stolz A, Kaplowitz N. PMID: 1569384.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family. J Biol Chem. 1991 Aug 15; 266(23):15253-7.
Stolz A, Rahimi-Kiani M, Ameis D, Chan E, Ronk M, Shively JE. PMID: 1714456.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Effect of indomethacin on the uptake, metabolism and excretion of 3-oxocholic acid: studies in isolated hepatocytes and perfused rat liver. Biochim Biophys Acta. 1991 Jul 30; 1084(3):247-50.
Takikawa H, Fernandez-Checa JC, Kuhlenkamp J, Stolz A, Ookhtens M, Kaplowitz N. PMID: 1888771.
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Translation:
AnimalsCells
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Oxidation and reduction of bile acid precursors by rat hepatic 3 alpha-hydroxysteroid dehydrogenase and inhibition by bile acids and indomethacin. Biochim Biophys Acta. 1990 Apr 02; 1043(2):153-6.
Takikawa H, Stolz A, Kuroki S, Kaplowitz N. PMID: 2317526.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Relationship between the newly identified bile acid binder and bile acid oxidoreductases in human liver. J Biol Chem. 1990 Feb 05; 265(4):2132-6.
Takikawa H, Stolz A, Sugiyama Y, Yoshida H, Yamanaka M, Kaplowitz N. PMID: 2153675.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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The role of cytoplasmic proteins in hepatic bile acid transport. Annu Rev Physiol. 1989; 51:161-76.
Stolz A, Takikawa H, Ookhtens M, Kaplowitz N. PMID: 2653179.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Tocopherol-binding proteins of hepatic cytosol. Ann N Y Acad Sci. 1989; 570:85-94.
Kaplowitz N, Yoshida H, Kuhlenkamp J, Slitsky B, Ren I, Stolz A. PMID: 2698112.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by rat hepatic 3 alpha-hydroxysteroid dehydrogenase. I. Studies with the purified enzyme, isolated rat hepatocytes, and inhibition by indomethacin. J Clin Invest. 1987 Sep; 80(3):852-60.
Takikawa H, Stolz A, Kaplowitz N. PMID: 3476498; PMCID: PMC442312.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Cyclical oxidation-reduction of the C3 position on bile acids catalyzed by 3 alpha-hydroxysteroid dehydrogenase. II. Studies in the prograde and retrograde single-pass, perfused rat liver and inhibition by indomethacin. J Clin Invest. 1987 Sep; 80(3):861-6.
Takikawa H, Ookhtens M, Stolz A, Kaplowitz N. PMID: 3476499; PMCID: PMC442313.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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3 alpha-hydroxysteroid dehydrogenase activity of the Y' bile acid binders in rat liver cytosol. Identification, kinetics, and physiologic significance. J Clin Invest. 1987 Feb; 79(2):427-34.
Stolz A, Takikawa H, Sugiyama Y, Kuhlenkamp J, Kaplowitz N. PMID: 3468121; PMCID: PMC424091.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Subunit heterogeneity of cationic human hepatic glutathione S-transferases. Pharmacology. 1987; 35(2):65-78.
Sugimoto M, Takikawa H, Stolz A, Kaplowitz N. PMID: 3628463.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Purification of a 32.5 kDa monomeric sulfotransferase from rat liver with activity for bile acids and phenolic steroids. FEBS Lett. 1986 Oct 27; 207(2):193-7.
Takikawa H, Stolz A, Kaplowitz N. PMID: 3464463.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Drug-induced hepatotoxicity. Ann Intern Med. 1986 Jun; 104(6):826-39.
Kaplowitz N, Aw TY, Simon FR, Stolz A. PMID: 3518564.
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PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Comparison of the affinities of newly identified human bile acid binder and cationic glutathione S-transferase for bile acids. J Lipid Res. 1986 Jun; 27(6):652-7.
Takikawa H, Stolz A, Sugimoto M, Sugiyama Y, Kaplowitz N. PMID: 3746134.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Cytosolic bile acid binding protein in rat liver: radioimmunoassay, molecular forms, developmental characteristics and organ distribution. Hepatology. 1986 May-Jun; 6(3):433-9.
Stolz A, Sugiyama Y, Kuhlenkamp J, Osadchey B, Yamada T, Belknap W, Balistreri W, Kaplowitz N. PMID: 3710432.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Organic anion-binding by human hepatic GSH S-transferases. Biochem Pharmacol. 1986 Jan 15; 35(2):354-6.
Takikawa H, Sugiyama Y, Stolz A, Sugimoto M, Kaplowitz N. PMID: 3942604.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Identification and partial purification of a unique phenolic steroid sulphotransferase in rat liver cytosol. Biochem J. 1984 Dec 15; 224(3):947-53.
Sugiyama Y, Stolz A, Sugimoto M, Kuhlenkamp J, Yamada T, Kaplowitz N. PMID: 6596951; PMCID: PMC1144532.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Identification and purification of a 36 kDa bile acid binder in human hepatic cytosol. FEBS Lett. 1984 Nov 05; 177(1):31-5.
Stolz A, Sugiyama Y, Kuhlenkamp J, Kaplowitz N. PMID: 6500050.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Evidence for a common high affinity binding site on glutathione S-transferase B for lithocholic acid and bilirubin. J Lipid Res. 1984 Nov; 25(11):1177-83.
Sugiyama Y, Stolz A, Sugimoto M, Kaplowitz N. PMID: 6520541.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Comparison of the binding affinities of five forms of rat glutathione S-transferases for bilirubin, sulfobromophthalein and hematin. Biochem Pharmacol. 1984 Nov 01; 33(21):3511-3.
Sugiyama Y, Sugimoto M, Stolz A, Kaplowitz N. PMID: 6497907.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Comparison of binding of thyroid hormone analogues to hepatic organic anion binding proteins. Biochim Biophys Acta. 1984 Sep 28; 801(2):184-8.
Sugiyama Y, Stolz A, Hershman JM, Kaplowitz N. PMID: 6477965.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Quantitation and characterization of a newly described organic anion binder by radioimmunoassay. Biochim Biophys Acta. 1984 Jul 30; 800(2):171-7.
Stolz A, Yamada T, Sugiyama Y, Belknap W, Kaplowitz N. PMID: 6743689.
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PubMed Mentions: Fields:
Translation:
Animals