Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Vassilios Papadopoulos

    TitleDean
    SchoolSchool of Pharmacy
    DepartmentAdministration
    Address1985 ZONAL AVE.
    Health Sciences Campus
    Los Angeles California 90033
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Papadopoulos V, Fan J, Zirkin B. Translocator protein (18 kDa): an update on its function in steroidogenesis. J Neuroendocrinol. 2017 Jul 01. PMID: 28667781.
        View in: PubMed
      2. Boisvert A, Jones S, Issop L, Erythropel HC, Papadopoulos V, Culty M. In vitro functional screening as a means to identify new plasticizers devoid of reproductive toxicity. Environ Res. 2016 Oct; 150:496-512. PMID: 27423704.
        View in: PubMed
      3. Fan J, Li X, Issop L, Culty M, Papadopoulos V. ACBD2/ECI2-Mediated Peroxisome-Mitochondria Interactions in Leydig Cell Steroid Biosynthesis. Mol Endocrinol. 2016 Jul; 30(7):763-82. PMID: 27167610.
        View in: PubMed
      4. Traore K, Martinez-Arguelles DB, Papadopoulos V, Chen H, Zirkin BR. Repeated exposures of the male Sprague Dawley rat reproductive tract to environmental toxicants: Do earlier exposures to di-(2-ethylhexyl)phthalate (DEHP) alter the effects of later exposures? Reprod Toxicol. 2016 Jun; 61:136-41. PMID: 27040317.
        View in: PubMed
      5. Li NC, Fan J, Papadopoulos V. Sterol Carrier Protein-2, a Nonspecific Lipid-Transfer Protein, in Intracellular Cholesterol Trafficking in Testicular Leydig Cells. PLoS One. 2016; 11(2):e0149728. PMID: 26901662; PMCID: PMC4762939.
      6. Chen H, Guo J, Ge R, Lian Q, Papadopoulos V, Zirkin BR. Steroidogenic fate of the Leydig cells that repopulate the testes of young and aged Brown Norway rats after elimination of the preexisting Leydig cells. Exp Gerontol. 2015 Dec; 72:8-15. PMID: 26335619; PMCID: PMC4654651 [Available on 12/01/16].
      7. Midzak A, Zirkin B, Papadopoulos V. Translocator protein: pharmacology and steroidogenesis. Biochem Soc Trans. 2015 Aug; 43(4):572-8. PMID: 26551695.
        View in: PubMed
      8. Li J, Papadopoulos V. Translocator protein (18 kDa) as a pharmacological target in adipocytes to regulate glucose homeostasis. Biochem Pharmacol. 2015 Sep 01; 97(1):99-110. PMID: 26123521.
        View in: PubMed
      9. Fan J, Campioli E, Midzak A, Culty M, Papadopoulos V. Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. Proc Natl Acad Sci U S A. 2015 Jun 09; 112(23):7261-6. PMID: 26039990; PMCID: PMC4466704.
      10. Midzak A, Denora N, Laquintana V, Cutrignelli A, Lopedota A, Franco M, Altomare CD, Papadopoulos V. 2-Phenylimidazo[1,2-a]pyridine-containing ligands of the 18-kDa translocator protein (TSPO) behave as agonists and antagonists of steroidogenesis in a mouse leydig tumor cell line. Eur J Pharm Sci. 2015 Aug 30; 76:231-7. PMID: 26002041.
        View in: PubMed
      11. Papadopoulos V, Aghazadeh Y, Fan J, Campioli E, Zirkin B, Midzak A. Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis. Mol Cell Endocrinol. 2015 Jun 15; 408:90-8. PMID: 25818881; PMCID: PMC4417383.
      12. Aghazadeh Y, Zirkin BR, Papadopoulos V. Pharmacological regulation of the cholesterol transport machinery in steroidogenic cells of the testis. Vitam Horm. 2015; 98:189-227. PMID: 25817870.
        View in: PubMed
      13. Issop L, Fan J, Lee S, Rone MB, Basu K, Mui J, Papadopoulos V. Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3. Endocrinology. 2015 Jan; 156(1):334-45. PMID: 25375035.
        View in: PubMed
      14. Leneveu-Jenvrin C, Connil N, Bouffartigues E, Papadopoulos V, Feuilloley MG, Chevalier S. Structure-to-function relationships of bacterial translocator protein (TSPO): a focus on Pseudomonas. Front Microbiol. 2014; 5:631. PMID: 25477872; PMCID: PMC4237140.
      15. Rone MB, Midzak AS, Martinez-Arguelles DB, Fan J, Ye X, Blonder J, Papadopoulos V. Steroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria. Biol Reprod. 2014 Oct; 91(4):96. PMID: 25210128; PMCID: PMC4435033.
      16. Aghazadeh Y, Martinez-Arguelles DB, Fan J, Culty M, Papadopoulos V. Induction of androgen formation in the male by a TAT-VDAC1 fusion peptide blocking 14-3-3? protein adaptor and mitochondrial VDAC1 interactions. Mol Ther. 2014 Oct; 22(10):1779-91. PMID: 24947306; PMCID: PMC4428399.
      17. Papadopoulos V. On the role of the translocator protein (18-kDa) TSPO in steroid hormone biosynthesis. Endocrinology. 2014 Jan; 155(1):15-20. PMID: 24364587.
        View in: PubMed
      18. Fan J, Papadopoulos V. Evolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animals. PLoS One. 2013; 8(10):e76701. PMID: 24124589; PMCID: PMC3790746.
      19. Zhou L, Beattie MC, Lin CY, Liu J, Traore K, Papadopoulos V, Zirkin BR, Chen H. Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cells. Reprod Toxicol. 2013 Dec; 42:95-101. PMID: 23969005; PMCID: PMC3836854.
      20. Beattie MC, Chen H, Fan J, Papadopoulos V, Miller P, Zirkin BR. Aging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells. Biol Reprod. 2013 Apr; 88(4):100. PMID: 23486914; PMCID: PMC4013884.
      21. Rone MB, Midzak AS, Issop L, Rammouz G, Jagannathan S, Fan J, Ye X, Blonder J, Veenstra T, Papadopoulos V. Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones. Mol Endocrinol. 2012 Nov; 26(11):1868-82. PMID: 22973050.
        View in: PubMed
      22. Wang HJ, Fan J, Papadopoulos V. Translocator protein (Tspo) gene promoter-driven green fluorescent protein synthesis in transgenic mice: an in vivo model to study Tspo transcription. Cell Tissue Res. 2012 Nov; 350(2):261-75. PMID: 22868914; PMCID: PMC3740157.
      23. Fan J, Papadopoulos V. Transcriptional regulation of translocator protein (Tspo) via a SINE B2-mediated natural antisense transcript in MA-10 Leydig cells. Biol Reprod. 2012 May; 86(5):147, 1-15. PMID: 22378763; PMCID: PMC3364927.
      24. Stanley EL, Johnston DS, Fan J, Papadopoulos V, Chen H, Ge RS, Zirkin BR, Jelinsky SA. Stem Leydig cell differentiation: gene expression during development of the adult rat population of Leydig cells. Biol Reprod. 2011 Dec; 85(6):1161-6. PMID: 21832170; PMCID: PMC3223250.
      25. Castillo AF, Fan J, Papadopoulos V, Podestá EJ. Hormone-dependent expression of a steroidogenic acute regulatory protein natural antisense transcript in MA-10 mouse tumor Leydig cells. PLoS One. 2011; 6(8):e22822. PMID: 21829656; PMCID: PMC3148237.
      26. Martinez-Arguelles DB, Guichard T, Culty M, Zirkin BR, Papadopoulos V. In utero exposure to the antiandrogen di-(2-ethylhexyl) phthalate decreases adrenal aldosterone production in the adult rat. Biol Reprod. 2011 Jul; 85(1):51-61. PMID: 21389346; PMCID: PMC3123382.
      27. Midzak AS, Chen H, Aon MA, Papadopoulos V, Zirkin BR. ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cells. Biol Reprod. 2011 May; 84(5):976-85. PMID: 21228212; PMCID: PMC3080423.
      28. Midzak A, Akula N, Lecanu L, Papadopoulos V. Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis. J Biol Chem. 2011 Mar 18; 286(11):9875-87. PMID: 21209087; PMCID: PMC3058962.
      29. Midzak A, Rone M, Aghazadeh Y, Culty M, Papadopoulos V. Mitochondrial protein import and the genesis of steroidogenic mitochondria. Mol Cell Endocrinol. 2011 Apr 10; 336(1-2):70-9. PMID: 21147195; PMCID: PMC3057322.
      30. Rupprecht R, Papadopoulos V, Rammes G, Baghai TC, Fan J, Akula N, Groyer G, Adams D, Schumacher M. Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders. Nat Rev Drug Discov. 2010 Dec; 9(12):971-88. PMID: 21119734.
        View in: PubMed
      31. Batarseh A, Papadopoulos V. Regulation of translocator protein 18 kDa (TSPO) expression in health and disease states. Mol Cell Endocrinol. 2010 Oct 07; 327(1-2):1-12. PMID: 20600583; PMCID: PMC2922062.
      32. Batarseh A, Li J, Papadopoulos V. Protein kinase C epsilon regulation of translocator protein (18 kDa) Tspo gene expression is mediated through a MAPK pathway targeting STAT3 and c-Jun transcription factors. Biochemistry. 2010 Jun 15; 49(23):4766-78. PMID: 20469933; PMCID: PMC2902160.
      33. Fan J, Traore K, Li W, Amri H, Huang H, Wu C, Chen H, Zirkin B, Papadopoulos V. Molecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cells. Endocrinology. 2010 Jul; 151(7):3348-62. PMID: 20463053; PMCID: PMC2903930.
      34. Fan J, Liu J, Culty M, Papadopoulos V. Acyl-coenzyme A binding domain containing 3 (ACBD3; PAP7; GCP60): an emerging signaling molecule. Prog Lipid Res. 2010 Jul; 49(3):218-34. PMID: 20043945; PMCID: PMC2873055.
      35. Fan J, Rone MB, Papadopoulos V. Translocator protein 2 is involved in cholesterol redistribution during erythropoiesis. J Biol Chem. 2009 Oct 30; 284(44):30484-97. PMID: 19729679; PMCID: PMC2781603.
      36. Ostuni MA, Péranzi G, Ducroc RA, Fasseu M, Vidic B, Dumont J, Papadopoulos V, Lacapere JJ. Distribution, pharmacological characterization and function of the 18 kDa translocator protein in rat small intestine. Biol Cell. 2009 Jul 31; 101(10):573-86. PMID: 19392661.
        View in: PubMed
      37. Papadopoulos V, Lecanu L. Translocator protein (18 kDa) TSPO: an emerging therapeutic target in neurotrauma. Exp Neurol. 2009 Sep; 219(1):53-7. PMID: 19409385; PMCID: PMC2728790.
      38. Favreau F, Rossard L, Zhang K, Desurmont T, Manguy E, Belliard A, Fabre S, Liu J, Han Z, Thuillier R, Papadopoulos V, Hauet T. Expression and modulation of translocator protein and its partners by hypoxia reoxygenation or ischemia and reperfusion in porcine renal models. Am J Physiol Renal Physiol. 2009 Jul; 297(1):F177-90. PMID: 19386723; PMCID: PMC2711711.
      39. Rone MB, Fan J, Papadopoulos V. Cholesterol transport in steroid biosynthesis: role of protein-protein interactions and implications in disease states. Biochim Biophys Acta. 2009 Jul; 1791(7):646-58. PMID: 19286473; PMCID: PMC2757135.
      40. Batarseh A, Giatzakis C, Papadopoulos V. Phorbol-12-myristate 13-acetate acting through protein kinase Cepsilon induces translocator protein (18-kDa) TSPO gene expression. Biochemistry. 2008 Dec 02; 47(48):12886-99. PMID: 18975922; PMCID: PMC2645926.
      41. Midzak AS, Chen H, Papadopoulos V, Zirkin BR. Leydig cell aging and the mechanisms of reduced testosterone synthesis. Mol Cell Endocrinol. 2009 Feb 05; 299(1):23-31. PMID: 18761053.
        View in: PubMed
      42. Ostuni MA, Tumilasci OR, Péranzi G, Cardoso EM, Contreras LN, Arregger AL, Papadopoulos V, Lacapere JJ. Effect of translocator protein (18 kDa)-ligand binding on neurotransmitter-induced salivary secretion in rat submandibular glands. Biol Cell. 2008 Jul; 100(7):427-39. PMID: 18269350.
        View in: PubMed
      43. Culty M, Thuillier R, Li W, Wang Y, Martinez-Arguelles DB, Benjamin CG, Triantafilou KM, Zirkin BR, Papadopoulos V. In utero exposure to di-(2-ethylhexyl) phthalate exerts both short-term and long-lasting suppressive effects on testosterone production in the rat. Biol Reprod. 2008 Jun; 78(6):1018-28. PMID: 18322279.
        View in: PubMed
      44. Ostuni MA, Ducroc R, Péranzi G, Tonon MC, Papadopoulos V, Lacapere JJ. Translocator protein (18 kDa) ligand PK 11195 induces transient mitochondrial Ca2+ release leading to transepithelial Cl- secretion in HT-29 human colon cancer cells. Biol Cell. 2007 Nov; 99(11):639-47. PMID: 17561806.
        View in: PubMed
      45. Rosenberg BG, Chen H, Folmer J, Liu J, Papadopoulos V, Zirkin BR. Gestational exposure to atrazine: effects on the postnatal development of male offspring. J Androl. 2008 May-Jun; 29(3):304-11. PMID: 17978342.
        View in: PubMed
      46. Giatzakis C, Batarseh A, Dettin L, Papadopoulos V. The role of Ets transcription factors in the basal transcription of the translocator protein (18 kDa). Biochemistry. 2007 Apr 24; 46(16):4763-74. PMID: 17402746; PMCID: PMC2529463.
      47. Liu Y, Dettin LE, Folmer J, Zirkin BR, Papadopoulos V. Abnormal morphology of spermatozoa in cytochrome P450 17alpha-hydroxylase/17, 20-lyase (CYP17) deficient mice. J Androl. 2007 May-Jun; 28(3):453-60. PMID: 17251596.
        View in: PubMed
      48. Veenman L, Papadopoulos V, Gavish M. Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response. Curr Pharm Des. 2007; 13(23):2385-405. PMID: 17692008.
        View in: PubMed
      49. Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapère JJ, Lindemann P, Norenberg MD, Nutt D, Weizman A, Zhang MR, Gavish M. Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function. Trends Pharmacol Sci. 2006 Aug; 27(8):402-9. PMID: 16822554.
        View in: PubMed
      50. Ge RS, Dong Q, Sottas CM, Papadopoulos V, Zirkin BR, Hardy MP. In search of rat stem Leydig cells: identification, isolation, and lineage-specific development. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2719-24. PMID: 16467141; PMCID: PMC1413776.
      51. Liu Y, Yao ZX, Bendavid C, Borgmeyer C, Han Z, Cavalli LR, Chan WY, Folmer J, Zirkin BR, Haddad BR, Gallicano GI, Papadopoulos V. Haploinsufficiency of cytochrome P450 17alpha-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice. Mol Endocrinol. 2005 Sep; 19(9):2380-9. PMID: 15890676.
        View in: PubMed
      52. Gazouli M, Yao ZX, Boujrad N, Corton JC, Culty M, Papadopoulos V. Effect of peroxisome proliferators on Leydig cell peripheral-type benzodiazepine receptor gene expression, hormone-stimulated cholesterol transport, and steroidogenesis: role of the peroxisome proliferator-activator receptor alpha. Endocrinology. 2002 Jul; 143(7):2571-83. PMID: 12072389.
        View in: PubMed
      53. Culty M, Luo L, Yao ZX, Chen H, Papadopoulos V, Zirkin BR. Cholesterol transport, peripheral benzodiazepine receptor, and steroidogenesis in aging Leydig cells. J Androl. 2002 May-Jun; 23(3):439-47. PMID: 12002446.
        View in: PubMed
      Vassilios's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _