Houda Alachkar

Title(s)Associate Professor of Clinical Pharmacy
SchoolUSC School of Pharmacy
Address1985 Zonal Ave.
Health Sciences Campus
Los Angeles CA 90089-9121
Phone+1 323 442 2696
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Isoform specific regulation of osteopontin by AKT2 in hepatocytes and livers. Cell Signal. 2025 Apr 09; 132:111799. Slarve I, Wang Y, Ding Y, Niu X, Tang Q, Jia C, Tu T, Hong H, Zhang G, Gu Y, Xu Z, Skinner S, He L, Hua B, Nguyen P, Zhou Y, Chen L, Ashouri K, Martynova A, Nakhoul C, Rastegarpour A, Alachkar H, Lenz HJ, El-Khoueiry A, Sher L, Chopra S, Yuan L, Stiles BL. PMID: 40216173.
      View in: PubMed   Mentions:    Fields:    
    2. Recognition, prevention, and management of adverse events associated with asparaginase / pegaspargase treatment of acute lymphoblastic leukemia in adults: consensus of an expert panel. Haematologica. 2025 Mar 20. Curran E, Luskin MR, Alachkar H, Aldoss I, Burke PW, Cassaday RD, Karol SE, Perissinotti AJ, Rank CU, Schmiegelow K, Webster J, Douer D. PMID: 40109190.
      View in: PubMed   Mentions:    Fields:    
    3. Corrigendum to "Characterization of upregulated adhesion GPCRs in acute myeloid leukemia" [Transl Res. 2019 Oct:212:26-35. doi: 10.1016/j.trsl.2019.05.004. Epub 2019 May 17.]. Transl Res. 2025 Jan; 275:62. Yang J, Wu S, Alachkar H. PMID: 39616108.
      View in: PubMed   Mentions:    Fields:    
    4. Development and characterization of human T-cell receptor (TCR) alpha and beta clones' library as biological standards and resources for TCR sequencing and engineering. Biol Methods Protoc. 2024; 9(1):bpae064. Wei YC, Pospiech M, Meng Y, Alachkar H. PMID: 39507623; PMCID: PMC11540440.
      View in: PubMed   Mentions:
    5. Low methylthioadenosine phosphorylase expression is associated with worse survival in patients with acute myeloid leukaemia. Clin Transl Med. 2024 Sep; 14(9):e70015. Xiao Y, Peng Q, Kumar AMS, Alachkar H. PMID: 39259513; PMCID: PMC11389529.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Corrigendum to "Anti-CD99 scFv-ELP nanoworms for the treatment of acute myeloid leukemia" [Nanomed: Nanotechnol Biol Med 29C (2020) 102236]. Nanomedicine. 2024 Nov; 62:102783. Vaikari VP, Park M, Keossayan L, MacKay JA, Alachkar H. PMID: 39190946.
      View in: PubMed   Mentions:    Fields:    
    7. Enhanced T cell activation and cytotoxicity against AML via targeted anti-CD99 nanoparticle treatment. Biomed Pharmacother. 2024 Oct; 179:117265. Kadam S, Ali A, Pospiech M, Onyemaechi S, Meng Y, Dhuri K, MacKay JA, Alachkar H. PMID: 39167846.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    8. FLT3/CD99 Bispecific Antibody-Based Nanoparticles for Acute Myeloid Leukemia. Cancer Res Commun. 2024 08 01; 4(8):1946-1962. Ali A, Phan A, Vaikari V, Park M, Pospiech M, Chu R, Meng Y, MacKay JA, Alachkar H. PMID: 39007347; PMCID: PMC11305399.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Differences in the mutational landscape of clonal hematopoiesis of indeterminate potential among races and between male and female patients with cancer. Exp Hematol. 2024 Oct; 138:104271. Dhuri K, Alachkar H. PMID: 38969020; PMCID: PMC12045072.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. The DNA methylation landscape across the TCR loci in patients with acute myeloid leukemia. Int Immunopharmacol. 2024 Sep 10; 138:112376. Pospiech M, Beckford J, Kumar AMS, Tamizharasan M, Brito J, Liang G, Mangul S, Alachkar H. PMID: 38917523.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. A rigorous benchmarking of alignment-based HLA typing algorithms for RNA-seq data. bioRxiv. 2024 Jan 16. Yu D, Ayyala R, Sadek SH, Chittampalli L, Farooq H, Jung J, Nahid AA, Boldirev G, Jung M, Park S, Nguyen A, Zelikovsky A, Mancuso N, Joo JWJ, Thompson RF, Alachkar H, Mangul S. PMID: 38293199; PMCID: PMC10827116.
      View in: PubMed   Mentions:
    12. Features of the TCR repertoire associate with patients' clinical and molecular characteristics in acute myeloid leukemia. Front Immunol. 2023; 14:1236514. Pospiech M, Tamizharasan M, Wei YC, Kumar AMS, Lou M, Milstein J, Alachkar H. PMID: 37928542; PMCID: PMC10620936.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Response to 'comment on rigorous benchmarking of T cell receptor repertoire profiling methods for cancer RNA sequencing' by Davydov A.N.; Bolotin D.A.; Poslavsky S. V. and Chudakov D.M. Brief Bioinform. 2023 09 22; 24(6). Huang YN, Vahed M, Peng K, Alachkar H, Mangul S. PMID: 37824736; PMCID: PMC10569746.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Genomics and transcriptomic alterations of the glutamate receptors in acute myeloid leukemia. Clin Transl Sci. 2023 10; 16(10):1828-1841. Alqahtani A, Wang M, Lou M, Alachkar H. PMID: 37670476; PMCID: PMC10582680.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. Rigorous benchmarking of T-cell receptor repertoire profiling methods for cancer RNA sequencing. Brief Bioinform. 2023 07 20; 24(4). Peng K, Nowicki TS, Campbell K, Vahed M, Peng D, Meng Y, Nagareddy A, Huang YN, Karlsberg A, Miller Z, Brito J, Nadel B, Pak VM, Abedalthagafi MS, Burkhardt AM, Alachkar H, Ribas A, Mangul S. PMID: 37291798; PMCID: PMC10359085.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    16. Deletion of CD36 exhibits limited impact on normal hematopoiesis and the leukemia microenvironment. Cell Mol Biol Lett. 2023 May 24; 28(1):45. Meng Y, Pospiech M, Ali A, Chandwani R, Vergel M, Onyemaechi S, Yaghmour G, Lu R, Alachkar H. PMID: 37226083; PMCID: PMC10210361.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    17. Profiling the epigenetic landscape of the antigen receptor repertoire: the missing epi-immunogenomics data. Nat Methods. 2023 04; 20(4):477-481. Aburajab R, Pospiech M, Alachkar H. PMID: 36522502; PMCID: PMC11058354.
      View in: PubMed   Mentions: 2     Fields:    
    18. Asparaginase toxicity in Hispanic adult and pediatric patients with acute lymphoblastic leukemia: current understanding. Expert Opin Drug Metab Toxicol. 2023 Jan-Jun; 19(6):357-366. Alqahtani A, Alhousari D, Ali A, Yaghmour G, Orgel E, Curran E, Stock W, Bhojwani D, Alachkar H. PMID: 37410014; PMCID: PMC11516125.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Prediction of Peptide and TCR CDR3 Loops in Formation of Class I MHC-Peptide-TCR Complexes Using Molecular Models with Solvation. Methods Mol Biol. 2023; 2673:273-287. Mehta NM, Li Y, Patel V, Li W, Morningstar-Kywi N, Pospiech M, Alachkar H, Haworth IS. PMID: 37258921; PMCID: PMC11059237.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    20. pyTCR: A comprehensive and scalable solution for TCR-Seq data analysis to facilitate reproducibility and rigor of immunogenomics research. Front Immunol. 2022; 13:954078. Peng K, Moore J, Vahed M, Brito J, Kao G, Burkhardt AM, Alachkar H, Mangul S. PMID: 36451811; PMCID: PMC9704496.
      View in: PubMed   Mentions: 2     Fields:    
    21. Hispanic ethnicity and the rs4880 variant in SOD2 are associated with elevated liver enzymes and bilirubin levels in children receiving asparaginase-containing chemotherapy for acute lymphoblastic leukemia. Biomed Pharmacother. 2022 Jun; 150:113000. Wu S, Wang M, Alqahtani A, Lou M, Stock W, Bhojwani D, Alachkar H. PMID: 35658244; PMCID: PMC9450009.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. CD99 in malignant hematopoiesis. Exp Hematol. 2022 02; 106:40-46. Ali A, Vaikari VP, Alachkar H. PMID: 34920053; PMCID: PMC9450008.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    23. Ancestral diversity is limited in published T cell receptor sequencing studies. Immunity. 2021 10 12; 54(10):2177-2179. Huang YN, Peng K, Popejoy AB, Hu J, Nowicki TS, Gold SM, Quintana-Murci L, Fuentes-Guajardo M, Shugay M, Greiff V, Burkhardt AM, Alachkar H, Mangul S. PMID: 34644550.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Diversity in immunogenomics: the value and the challenge. Nat Methods. 2021 06; 18(6):588-591. Peng K, Safonova Y, Shugay M, Popejoy AB, Rodriguez OL, Breden F, Brodin P, Burkhardt AM, Bustamante C, Cao-Lormeau VM, Corcoran MM, Duffy D, Fuentes-Guajardo M, Fujita R, Greiff V, Jönsson VD, Liu X, Quintana-Murci L, Rossetti M, Xie J, Yaari G, Zhang W, Abedalthagafi MS, Adekoya KO, Ahmed RA, Chang WC, Gray C, Nakamura Y, Lees WD, Khatri P, Alachkar H, Scheepers C, Watson CT, Karlsson Hedestam GB, Mangul S. PMID: 34002093; PMCID: PMC8842483.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    25. Deregulation of apolipoprotein C2 gene in cancer: A potential metabolic vulnerability. Clin Transl Med. 2021 06; 11(6):e406. Liu Y, Meng Y, Zhang T, Alachkar H. PMID: 34185418; PMCID: PMC8161511.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    26. Profiling of T Cell Repertoire in SARS-CoV-2-Infected COVID-19 Patients Between Mild Disease and Pneumonia. J Clin Immunol. 2021 08; 41(6):1131-1145. Chang CM, Feng PH, Wu TH, Alachkar H, Lee KY, Chang WC. PMID: 33950324; PMCID: PMC8096628.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCellsPHPublic Health
    27. Strategies targeting FLT3 beyond the kinase inhibitors. Pharmacol Ther. 2021 09; 225:107844. Almatani MF, Ali A, Onyemaechi S, Zhao Y, Gutierrez L, Vaikari VP, Alachkar H. PMID: 33811956; PMCID: PMC11490306.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    28. OTS167 blocks FLT3 translation and synergizes with FLT3 inhibitors in FLT3 mutant acute myeloid leukemia. Blood Cancer J. 2021 03 03; 11(3):48. Eisfelder BJ, Saygin C, Wynne J, Colton MW, Fischietti M, Beauchamp EM, Cheng JX, Odenike O, Roboz G, Alachkar H, Stock W. PMID: 33658483; PMCID: PMC7930094.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    29. Apolipoprotein C2 - CD36 Promotes Leukemia Growth and Presents a Targetable Axis in Acute Myeloid Leukemia. Blood Cancer Discov. 2020 09; 1(2):198-213. Zhang T, Yang J, Vaikari VP, Beckford JS, Wu S, Akhtari M, Alachkar H. PMID: 32944714; PMCID: PMC7494214.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    30. Deciphering the TCR Repertoire to Solve the COVID-19 Mystery. Trends Pharmacol Sci. 2020 08; 41(8):518-530. Gutierrez L, Beckford J, Alachkar H. PMID: 32576386; PMCID: PMC7305739.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    31. Anti-CD99 scFv-ELP nanoworms for the treatment of acute myeloid leukemia. Nanomedicine. 2020 10; 29:102236. Vaikari VP, Park M, Keossayan L, MacKay JA, Alachkar H. PMID: 32535112; PMCID: PMC7508895.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    32. Anti-FLT3 nanoparticles for acute myeloid leukemia: Preclinical pharmacology and pharmacokinetics. J Control Release. 2020 08 10; 324:317-329. Park M, Vaikari VP, Lam AT, Zhang Y, MacKay JA, Alachkar H. PMID: 32428520; PMCID: PMC7473778.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    33. Human Granulocyte-Macrophage Colony-Stimulating Factor Fused to Elastin-Like Polypeptides Assembles Biologically-Active Nanoparticles. Bioconjug Chem. 2020 05 20; 31(5):1551-1561. Park M, Vaikari VP, Dhandhukia JP, Alachkar H, MacKay JA. PMID: 32319752; PMCID: PMC7489497.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia. Haematologica. 2020 04; 105(4):999-1012. Vaikari VP, Du Y, Wu S, Zhang T, Metzeler K, Batcha AMN, Herold T, Hiddemann W, Akhtari M, Alachkar H. PMID: 31371417; PMCID: PMC7109747.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    35. CD97 expression is associated with poor overall survival in acute myeloid leukemia. Exp Hematol. 2019 07; 75:64-73.e4. Vaikari VP, Yang J, Wu S, Alachkar H. PMID: 31260716; PMCID: PMC7473776.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. Characterization of upregulated adhesion GPCRs in acute myeloid leukemia. Transl Res. 2019 10; 212:26-35. Yang J, Wu S, Alachkar H. PMID: 31153896; PMCID: PMC7473775.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    37. The mitochondrial transcription machinery genes are upregulated in acute myeloid leukemia and associated with poor clinical outcome. Metabol Open. 2019 Jun; 2:100009. Wu S, Fahmy N, Alachkar H. PMID: 32812906; PMCID: PMC7424792.
      View in: PubMed   Mentions: 7  
    38. Midostaurin reduces Regulatory T cells markers in Acute Myeloid Leukemia. Sci Rep. 2018 12 03; 8(1):17544. Gutierrez L, Jang M, Zhang T, Akhtari M, Alachkar H. PMID: 30510164; PMCID: PMC6277419.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    39. Clinical and laboratory features of seventy-eight UK patients with Good's syndrome (thymoma and hypogammaglobulinaemia). Clin Exp Immunol. 2019 01; 195(1):132-138. Zaman M, Huissoon A, Buckland M, Patel S, Alachkar H, Edgar JD, Thomas M, Arumugakani G, Baxendale H, Burns S, Williams AP, Jolles S, Herriot R, Sargur RB, Arkwright PD. PMID: 30216434; PMCID: PMC6300645.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    40. Characterization of Mutations in the Mitochondrial Encoded Electron Transport Chain Complexes in Acute Myeloid Leukemia. Sci Rep. 2018 09 05; 8(1):13301. Wu S, Akhtari M, Alachkar H. PMID: 30185817; PMCID: PMC6125587.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    41. Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia. J Transl Med. 2018 06 20; 16(1):170. Wu S, Du Y, Beckford J, Alachkar H. PMID: 29925392; PMCID: PMC6009962.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCells
    42. The United Kingdom Primary Immune Deficiency (UKPID) registry 2012 to 2017. Clin Exp Immunol. 2018 06; 192(3):284-291. Shillitoe B, Bangs C, Guzman D, Gennery AR, Longhurst HJ, Slatter M, Edgar DM, Thomas M, Worth A, Huissoon A, Arkwright PD, Jolles S, Bourne H, Alachkar H, Savic S, Kumararatne DS, Patel S, Baxendale H, Noorani S, Yong PFK, Waruiru C, Pavaladurai V, Kelleher P, Herriot R, Bernatonienne J, Bhole M, Steele C, Hayman G, Richter A, Gompels M, Chopra C, Garcez T, Buckland M. PMID: 29878323; PMCID: PMC5980391.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    43. The era of immunogenomics/immunopharmacogenomics. J Hum Genet. 2018 Jul; 63(8):865-875. Zewde M, Kiyotani K, Park JH, Fang H, Yap KL, Yew PY, Alachkar H, Kato T, Mai TH, Ikeda Y, Matsuda T, Liu X, Ren L, Deng B, Harada M, Nakamura Y. PMID: 29785006.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    44. Quantitative characterization of T-cell repertoire and biomarkers in kidney transplant rejection. BMC Nephrol. 2016 11 21; 17(1):181. Alachkar H, Mutonga M, Kato T, Kalluri S, Kakuta Y, Uemura M, Imamura R, Nonomura N, Vujjini V, Alasfar S, Rabb H, Nakamura Y, Alachkar N. PMID: 27871261; PMCID: PMC5117555.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    45. Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia. Pharmacogenomics J. 2017 06; 17(3):274-279. Alachkar H, Fulton N, Sanford B, Malnassy G, Mutonga M, Larson RA, Bloomfield CD, Marcucci G, Nakamura Y, Stock W. PMID: 27019981; PMCID: PMC5089920.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    46. SUV420H1 enhances the phosphorylation and transcription of ERK1 in cancer cells. Oncotarget. 2015 Dec 22; 6(41):43162-71. Vougiouklakis T, Sone K, Saloura V, Cho HS, Suzuki T, Dohmae N, Alachkar H, Nakamura Y, Hamamoto R. PMID: 26586479; PMCID: PMC4791223.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    47. T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia. Oncotarget. 2015 Oct 20; 6(32):33410-25. Alachkar H, Mutonga M, Malnassy G, Park JH, Fulton N, Woods A, Meng L, Kline J, Raca G, Odenike O, Takamatsu N, Miyamoto T, Matsuo Y, Stock W, Nakamura Y. PMID: 26450903; PMCID: PMC4741775.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    48. Targeting Suppressor of Variegation 3-9 Homologue 2 (SUV39H2) in Acute Lymphoblastic Leukemia (ALL). Transl Oncol. 2015 Oct; 8(5):368-375. Mutonga M, Tamura K, Malnassy G, Fulton N, de Albuquerque A, Hamamoto R, Stock W, Nakamura Y, Alachkar H. PMID: 26500027; PMCID: PMC4631083.
      View in: PubMed   Mentions: 14  
    49. Deep-sequencing of the T-cell receptor repertoire in patients with haplo-cord and matched-donor transplants. Chimerism. 2015 Jul 03; 6(3):47-9. Alachkar H, Nakamura Y. PMID: 26745665; PMCID: PMC5154355.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    50. Quantitative characterization of T-cell repertoire in allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 2015 Sep; 50(9):1227-34. Yew PY, Alachkar H, Yamaguchi R, Kiyotani K, Fang H, Yap KL, Liu HT, Wickrema A, Artz A, van Besien K, Imoto S, Miyano S, Bishop MR, Stock W, Nakamura Y. PMID: 26052909; PMCID: PMC4559843.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCellsCTClinical Trials
    51. Pharmacological targeting of miR-155 via the NEDD8-activating enzyme inhibitor MLN4924 (Pevonedistat) in FLT3-ITD acute myeloid leukemia. Leukemia. 2015 Oct; 29(10):1981-92. Khalife J, Radomska HS, Santhanam R, Huang X, Neviani P, Saultz J, Wang H, Wu YZ, Alachkar H, Anghelina M, Dorrance A, Curfman J, Bloomfield CD, Medeiros BC, Perrotti D, Lee LJ, Lee RJ, Caligiuri MA, Pichiorri F, Croce CM, Garzon R, Guzman ML, Mendler JH, Marcucci G. PMID: 25971362; PMCID: PMC4868182.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    52. Spectrum and management of complement immunodeficiencies (excluding hereditary angioedema) across Europe. J Clin Immunol. 2015 Feb; 35(2):199-205. Turley AJ, Gathmann B, Bangs C, Bradbury M, Seneviratne S, Gonzalez-Granado LI, Hackett S, Kutukculer N, Alachkar H, Hambleton S, Ritterbusch H, Kralickova P, Marodi L, Seidel MG, Dueckers G, Roesler J, Huissoon A, Baxendale H, Litzman J, Arkwright PD. PMID: 25663093.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    53. Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia. Oncotarget. 2014 Dec 15; 5(23):12371-82. Alachkar H, Mutonga MB, Metzeler KH, Fulton N, Malnassy G, Herold T, Spiekermann K, Bohlander SK, Hiddemann W, Matsuo Y, Stock W, Nakamura Y. PMID: 25365263; PMCID: PMC4323011.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    54. TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. Sci Transl Med. 2014 Oct 22; 6(259):259ra145. Matsuo Y, Park JH, Miyamoto T, Yamamoto S, Hisada S, Alachkar H, Nakamura Y. PMID: 25338756.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    55. WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck. Mol Cancer Res. 2015 Feb; 13(2):293-304. Saloura V, Cho HS, Kiyotani K, Alachkar H, Zuo Z, Nakakido M, Tsunoda T, Seiwert T, Lingen M, Licht J, Nakamura Y, Hamamoto R. PMID: 25280969.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    56. SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome. J Clin Invest. 2014 Apr; 124(4):1512-24. Alachkar H, Santhanam R, Maharry K, Metzeler KH, Huang X, Kohlschmidt J, Mendler JH, Benito JM, Hickey C, Neviani P, Dorrance AM, Anghelina M, Khalife J, Tarighat SS, Volinia S, Whitman SP, Paschka P, Hoellerbauer P, Wu YZ, Han L, Bolon BN, Blum W, Mrózek K, Carroll AJ, Perrotti D, Andreeff M, Caligiuri MA, Konopleva M, Garzon R, Bloomfield CD, Marcucci G. PMID: 24590286; PMCID: PMC3973087.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    57. A UK national audit of hereditary and acquired angioedema. Clin Exp Immunol. 2014 Jan; 175(1):59-67. Jolles S, Williams P, Carne E, Mian H, Huissoon A, Wong G, Hackett S, Lortan J, Platts V, Longhurst H, Grigoriadou S, Dempster J, Deacock S, Khan S, Darroch J, Simon C, Thomas M, Pavaladurai V, Alachkar H, Herwadkar A, Abinun M, Arkwright P, Tarzi M, Helbert M, Bangs C, Pastacaldi C, Phillips C, Bennett H, El-Shanawany T. PMID: 23786259; PMCID: PMC3898555.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    58. The United Kingdom Primary Immune Deficiency (UKPID) Registry: report of the first 4 years' activity 2008-2012. Clin Exp Immunol. 2014 Jan; 175(1):68-78. Edgar JD, Buckland M, Guzman D, Conlon NP, Knerr V, Bangs C, Reiser V, Panahloo Z, Workman S, Slatter M, Gennery AR, Davies EG, Allwood Z, Arkwright PD, Helbert M, Longhurst HJ, Grigoriadou S, Devlin LA, Huissoon A, Krishna MT, Hackett S, Kumararatne DS, Condliffe AM, Baxendale H, Henderson K, Bethune C, Symons C, Wood P, Ford K, Patel S, Jain R, Jolles S, El-Shanawany T, Alachkar H, Herwadkar A, Sargur R, Shrimpton A, Hayman G, Abuzakouk M, Spickett G, Darroch CJ, Paulus S, Marshall SE, McDermott EM, Heath PT, Herriot R, Noorani S, Turner M, Khan S, Grimbacher B. PMID: 23841717; PMCID: PMC3898556.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCTClinical Trials
    59. Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia. J Hematol Oncol. 2013 Mar 16; 6:21. Alachkar H, Santhanam R, Harb JG, Lucas DM, Oaks JJ, Hickey CJ, Pan L, Kinghorn AD, Caligiuri MA, Perrotti D, Byrd JC, Garzon R, Grever MR, Marcucci G. PMID: 23497456; PMCID: PMC3623627.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    60. Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia. Blood. 2013 Jan 03; 121(1):159-69. Hickey CJ, Schwind S, Radomska HS, Dorrance AM, Santhanam R, Mishra A, Wu YZ, Alachkar H, Maharry K, Nicolet D, Mrózek K, Walker A, Eiring AM, Whitman SP, Becker H, Perrotti D, Wu LC, Zhao X, Fehniger TA, Vij R, Byrd JC, Blum W, Lee LJ, Caligiuri MA, Bloomfield CD, Garzon R, Marcucci G. PMID: 23100311; PMCID: PMC3538328.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    61. Determination of cellular uptake and intracellular levels of Cenersen (Aezea(®), EL625), a p53 antisense oligonucleotide in acute myeloid leukemia cells. J Pharm Biomed Anal. 2012 Dec; 71:228-32. Alachkar H, Xie Z, Marcucci G, Chan KK. PMID: 22944355; PMCID: PMC4201859.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    62. Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms. Eur J Hum Genet. 2011 Jan; 19(1):76-83. Smith RM, Alachkar H, Papp AC, Wang D, Mash DC, Wang JC, Bierut LJ, Sadee W. PMID: 20700147; PMCID: PMC2995013.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    63. Allelic mRNA expression of sortilin-1 (SORL1) mRNA in Alzheimer's autopsy brain tissues. Neurosci Lett. 2008 Dec 19; 448(1):120-4. Alachkar H, Kataki M, Scharre DW, Papp A, Sadee W. PMID: 18938222; PMCID: PMC2612539.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    64. Skin penetration and lag times of neat and aqueous diethyl phthalate, 1,2-dichloroethane and naphthalene. Cutan Ocul Toxicol. 2007; 26(2):147-60. Frasch HF, Barbero AM, Alachkar H, McDougal JN. PMID: 17612981.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
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