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    Todd A. Alonzo, PhD

    TitleProfessor of Research Preventive Medicine
    SchoolKeck School of Medicine of USC
    DepartmentPreventive Medicine
    AddressChildren's Oncology Group
    Health Sciences Campus
    Monrovia California 91016
    Phone+1 626 241 1522
    vCardDownload vCard
      Other Positions
      TitleGroup Statistician For Children's Oncology Group


      Collapse Overview 
      Collapse Overview
      Todd Alonzo is a Professor of Research in the Department of Preventive Medicine, University of Southern California. He received his undergraduate degree at the California State Polytechnic University, San Luis Obispo, California in Statistics in 1994 and received both his MS and his PhD in Biostatistics in 1997 and 2000 from the University of Washington, Seattle. Dr. Alonzo’s main areas of research interest are the statistical methods for analysis of biomarkers and medical diagnostic and screening tests, clinical trials, and the design and analysis of pediatric acute myelogenous leukemia studies. He has published over 115 peer-reviewed articles including 18 as first author and written two book chapters. Dr. Alonzo has been member of the Editorial Board for Biometrics, Pediatric Blood Cancer, and Biometrical Journal and has acted as a reviewer for 30 scientific journals. He is also a member of several Data Safety and Monitoring Boards. Dr. Alonzo was the President of the International Biometric Society Western Northern America Region (WNAR) in 2009.


      Collapse Biography 
      Collapse Awards and Honors
      University of Washington2000• Senior Biostatistics Award, Department of Biostatistics
      1999• ENAR Biometrics Society Distinguished Student Paper Award
      1999• WNAR Biometrics Society Best Student Oral Presentation
      NIH1995Predoctoral Cardiovascular Biostatistics Training Grant

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Voigt AP, Eidenschink Brodersen L, Alonzo T, Gerbing RB, Menssen AJ, Wilson ER, Kahwash S, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S, Wells DA, Loken MR. Phenotype in combination with genotype improves outcome prediction in acute myeloid leukemia: a report from Children's Oncology Group protocol AAML0531. Haematologica. 2017 Sep 07. PMID: 28883080.
        View in: PubMed
      2. Kutny MA, Alonzo T, Gerbing RB, Wang YC, Raimondi SC, Hirsch BA, Fu CH, Meshinchi S, Gamis AS, Feusner JH, Gregory JJ. Arsenic Trioxide Consolidation Allows Anthracycline Dose Reduction for Pediatric Patients With Acute Promyelocytic Leukemia: Report From the Children's Oncology Group Phase III Historically Controlled Trial AAML0631. J Clin Oncol. 2017 Sep 10; 35(26):3021-3029. PMID: 28767288.
        View in: PubMed
      3. Guest EM, Aplenc R, Sung L, Raimondi SC, Hirsch BA, Alonzo T, Gerbing RB, Wang YJ, Kahwash SB, Heerema-McKenney A, Meshinchi S, Gamis AS. Gemtuzumab ozogamicin in infants with AML: results from the Children's Oncology Group trials AAML03P1 and AAML0531. Blood. 2017 Aug 17; 130(7):943-945. PMID: 28674028.
        View in: PubMed
      4. Lamba JK, Chauhan L, Shin M, Loken MR, Pollard JA, Wang YC, Ries RE, Aplenc R, Hirsch BA, Raimondi SC, Walter RB, Bernstein ID, Gamis AS, Alonzo T, Meshinchi S. CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531. J Clin Oncol. 2017 Aug 10; 35(23):2674-2682. PMID: 28644774.
        View in: PubMed
      5. Miller TP, Li Y, Kavcic M, Getz KD, Huang YV, Sung L, Alonzo T, Gerbing R, Daves MH, Horton TM, Pulsipher MA, Pollard J, Bagatell R, Seif AE, Fisher BT, Luger S, Gamis AS, Adamson PC, Aplenc R. Center-level variation in accuracy of adverse event reporting in a clinical trial for pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Haematologica. 2017 Sep; 102(9):e340-e343. PMID: 28642300.
        View in: PubMed
      6. Hanley MJ, Mould DR, Taylor TJ, Gupta N, Suryanarayan K, Neuwirth R, Esseltine DL, Horton TM, Aplenc R, Alonzo T, Lu X, Milton A, Venkatakrishnan K. Population Pharmacokinetic Analysis of Bortezomib in Pediatric Leukemia Patients: Model-Based Support for Body Surface Area-Based Dosing Over the 2- to 16-Year Age Range. J Clin Pharmacol. 2017 Sep; 57(9):1183-1193. PMID: 28419486.
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      7. Vujkovic M, Attiyeh EF, Ries RE, Goodman EK, Ding Y, Kavcic M, Alonzo T, Wang YC, Gerbing RB, Sung L, Hirsch B, Raimondi S, Gamis AS, Meshinchi S, Aplenc R. Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children's Oncology Group report. Blood. 2017 Jun 08; 129(23):3051-3058. PMID: 28411282.
        View in: PubMed
      8. Taub JW, Berman JN, Hitzler JK, Sorrell AD, Lacayo NJ, Mast K, Head D, Raimondi S, Hirsch B, Ge Y, Gerbing RB, Wang YC, Alonzo T, Campana D, Coustan-Smith E, Mathew P, Gamis AS. Improved outcomes for myeloid leukemia of Down syndrome: a report from the Children's Oncology Group AAML0431 trial. Blood. 2017 Jun 22; 129(25):3304-3313. PMID: 28389462.
        View in: PubMed
      9. Tarlock K, Alonzo T, Loken MR, Gerbing RB, Ries RE, Aplenc R, Sung L, Raimondi SC, Hirsch BA, Kahwash SB, McKenney A, Kolb EA, Gamis AS, Meshinchi S. Disease Characteristics and Prognostic Implications of Cell-Surface FLT3 Receptor (CD135) Expression in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group. Clin Cancer Res. 2017 Jul 15; 23(14):3649-3656. PMID: 28108543.
        View in: PubMed
      10. Laszlo GS, Alonzo T, Gudgeon CJ, Harrington KH, Kentsis A, Gerbing RB, Wang YC, Ries RE, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S, Walter RB. Erratum to: High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. J Hematol Oncol. 2016 Nov 30; 9(1):133. PMID: 27903291.
        View in: PubMed
      11. Brown FC, Cifani P, Drill E, He J, Still E, Zhong S, Balasubramanian S, Pavlick D, Yilmazel B, Knapp KM, Alonzo T, Meshinchi S, Stone RM, Kornblau SM, Marcucci G, Gamis AS, Byrd JC, Gonen M, Levine RL, Kentsis A. Genomics of primary chemoresistance and remission induction failure in paediatric and adult acute myeloid leukaemia. Br J Haematol. 2017 Jan; 176(1):86-91. PMID: 27766616.
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      12. Niewerth D, Kaspers GJ, Jansen G, van Meerloo J, Zweegman S, Jenkins G, Whitlock JA, Hunger SP, Lu X, Alonzo T, van de Ven PM, Horton TM, Cloos J. Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy. J Hematol Oncol. 2016 Sep 06; 9(1):82. PMID: 27599459; PMCID: PMC5011854.
      13. Ramamurthy R, Hughes M, Morris V, Bolouri H, Gerbing RB, Wang YC, Loken MR, Raimondi SC, Hirsch BA, Gamis AS, Oehler VG, Alonzo T, Meshinchi S. miR-155 expression and correlation with clinical outcome in pediatric AML: A report from Children's Oncology Group. Pediatr Blood Cancer. 2016 Dec; 63(12):2096-2103. PMID: 27511899.
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      14. Vujkovic M, Aplenc R, Alonzo T, Gamis AS, Li Y. Comparing Analytic Methods for Longitudinal GWAS and a Case-Study Evaluating Chemotherapy Course Length in Pediatric AML. A Report from the Children's Oncology Group. Front Genet. 2016; 7:139. PMID: 27547214; PMCID: PMC4974249.
      15. Getz KD, Miller TP, Seif AE, Li Y, Huang YS, Alonzo T, Gerbing R, Sung L, Hall M, Bagatell R, Gamis A, Fisher BT, Aplenc R. Early discharge as a mediator of greater ICU-level care requirements in patients not enrolled on the AAML0531 clinical trial: a Children's Oncology Group report. Cancer Med. 2016 Sep; 5(9):2412-6. PMID: 27474232.
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      16. Sung L, Aplenc R, Alonzo T, Gerbing RB, Wang YC, Meshinchi S, Gamis AS. Association between prolonged neutropenia and reduced relapse risk in pediatric AML: A report from the children's oncology group. Int J Cancer. 2016 Nov 01; 139(9):1930-5. PMID: 27312107; PMCID: PMC4990479 [Available on 11/01/17].
      17. Gerbing RB, Alonzo T, Sung L, Gamis AS, Meshinchi S, Plon SE, Bertuch AA, Gramatges MM. Shorter Remission Telomere Length Predicts Delayed Neutrophil Recovery After Acute Myeloid Leukemia Therapy: A Report From the Children's Oncology Group. J Clin Oncol. 2016 Jun 27. PMID: 27354474.
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      18. Zhang Y, Alonzo T. Inverse probability weighting estimation of the volume under the ROC surface in the presence of verification bias. Biom J. 2016 Nov; 58(6):1338-1356. PMID: 27338713.
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      19. Maxson JE, Ries RE, Wang YC, Gerbing RB, Kolb EA, Thompson SL, Guidry Auvil JM, Marra MA, Ma Y, Zong Z, Mungall AJ, Moore R, Long W, Gesuwan P, Davidsen TM, Hermida LC, Hughes SB, Farrar JE, Radich JP, Smith MA, Gerhard DS, Gamis AS, Alonzo T, Meshinchi S. CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML. Blood. 2016 Jun 16; 127(24):3094-8. PMID: 27143256; PMCID: PMC4911865 [Available on 06/16/17].
      20. de Rooij JD, Masetti R, van den Heuvel-Eibrink MM, Cayuela JM, Trka J, Reinhardt D, Rasche M, Sonneveld E, Alonzo T, Fornerod M, Zimmermann M, Pigazzi M, Pieters R, Meshinchi S, Zwaan CM, Locatelli F. Recurrent abnormalities can be used for risk group stratification in pediatric AMKL: a retrospective intergroup study. Blood. 2016 Jun 30; 127(26):3424-30. PMID: 27114462.
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      21. Cremer ML, Maza M, Alfaro KM, Kim JJ, Ditzian LR, Villalta S, Alonzo T, Felix JC, Castle PE, Gage JC. Introducing a High-Risk HPV DNA Test Into a Public Sector Screening Program in El Salvador. J Low Genit Tract Dis. 2016 Apr; 20(2):145-50. PMID: 26890683; PMCID: PMC4819528.
      22. Farrar JE, Schuback HL, Ries RE, Wai D, Hampton OA, Trevino LR, Alonzo T, Guidry Auvil JM, Davidsen TM, Gesuwan P, Hermida L, Muzny DM, Dewal N, Rustagi N, Lewis LR, Gamis AS, Wheeler DA, Smith MA, Gerhard DS, Meshinchi S. Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse. Cancer Res. 2016 04 15; 76(8):2197-205. PMID: 26941285; PMCID: PMC4873364 [Available on 04/15/17].
      23. Miller TP, Li Y, Kavcic M, Troxel AB, Huang YS, Sung L, Alonzo T, Gerbing R, Hall M, Daves MH, Horton TM, Pulsipher MA, Pollard JA, Bagatell R, Seif AE, Fisher BT, Luger S, Gamis AS, Adamson PC, Aplenc R. Accuracy of Adverse Event Ascertainment in Clinical Trials for Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2016 May 01; 34(13):1537-43. PMID: 26884558; PMCID: PMC4872308 [Available on 04/01/17].
      24. Pollard JA, Loken M, Gerbing RB, Raimondi SC, Hirsch BA, Aplenc R, Bernstein ID, Gamis AS, Alonzo T, Meshinchi S. CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531. J Clin Oncol. 2016 Mar 01; 34(7):747-55. PMID: 26786921; PMCID: PMC4872025 [Available on 12/01/16].
      25. Miller TP, Getz KD, Kavcic M, Li Y, Huang YS, Sung L, Alonzo T, Gerbing R, Daves M, Horton TM, Pulsipher MA, Pollard J, Bagatell R, Seif AE, Fisher BT, Gamis AS, Aplenc R. A comparison of discharge strategies after chemotherapy completion in pediatric patients with acute myeloid leukemia: a report from the Children's Oncology Group. Leuk Lymphoma. 2016 Jul; 57(7):1567-74. PMID: 26727639; PMCID: PMC4899280.
      26. Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen SR, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo T, Getz G, Gruber TA, Golub TR, Stegmaier K, Loh ML. Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia. Nat Genet. 2016 Jan; 48(1):101. PMID: 26711114.
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      27. Tarlock K, Alonzo T, Gerbing RB, Raimondi SC, Hirsch BA, Sung L, Pollard JA, Aplenc R, Loken MR, Gamis AS, Meshinchi S. Gemtuzumab Ozogamicin Reduces Relapse Risk in FLT3/ITD Acute Myeloid Leukemia: A Report from the Children's Oncology Group. Clin Cancer Res. 2016 Apr 15; 22(8):1951-7. PMID: 26644412; PMCID: PMC4834220 [Available on 04/15/17].
      28. Li Y, Hall M, Fisher BT, Seif AE, Huang YS, Bagatell R, Getz KD, Alonzo T, Gerbing RB, Sung L, Adamson PC, Gamis A, Aplenc R. Merging Children's Oncology Group Data with an External Administrative Database Using Indirect Patient Identifiers: A Report from the Children's Oncology Group. PLoS One. 2015; 10(11):e0143480. PMID: 26606521; PMCID: PMC4659568.
      29. Klein K, Kaspers G, Harrison CJ, Beverloo HB, Reedijk A, Bongers M, Cloos J, Pession A, Reinhardt D, Zimmerman M, Creutzig U, Dworzak M, Alonzo T, Johnston D, Hirsch B, Zapotocky M, De Moerloose B, Fynn A, Lee V, Taga T, Tawa A, Auvrignon A, Zeller B, Forestier E, Salgado C, Balwierz W, Popa A, Rubnitz J, Raimondi S, Gibson B. Clinical Impact of Additional Cytogenetic Aberrations, cKIT and RAS Mutations, and Treatment Elements in Pediatric t(8;21)-AML: Results From an International Retrospective Study by the International Berlin-Frankfurt-Münster Study Group. J Clin Oncol. 2015 Dec 20; 33(36):4247-58. PMID: 26573082.
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      30. Laszlo GS, Alonzo T, Gudgeon CJ, Harrington KH, Kentsis A, Gerbing RB, Wang YC, Ries RE, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S, Walter RB. High expression of myocyte enhancer factor 2C (MEF2C) is associated with adverse-risk features and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. J Hematol Oncol. 2015 Oct 20; 8:115. PMID: 26487643; PMCID: PMC4618184.
      31. Stieglitz E, Taylor-Weiner AN, Chang TY, Gelston LC, Wang YD, Mazor T, Esquivel E, Yu A, Seepo S, Olsen SR, Rosenberg M, Archambeault SL, Abusin G, Beckman K, Brown PA, Briones M, Carcamo B, Cooper T, Dahl GV, Emanuel PD, Fluchel MN, Goyal RK, Hayashi RJ, Hitzler J, Hugge C, Liu YL, Messinger YH, Mahoney DH, Monteleone P, Nemecek ER, Roehrs PA, Schore RJ, Stine KC, Takemoto CM, Toretsky JA, Costello JF, Olshen AB, Stewart C, Li Y, Ma J, Gerbing RB, Alonzo T, Getz G, Gruber TA, Golub TR, Stegmaier K, Loh ML. The genomic landscape of juvenile myelomonocytic leukemia. Nat Genet. 2015 Nov; 47(11):1326-33. PMID: 26457647.
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      32. Stevens AM, Ruiz MJ, Gerbing RB, Alonzo T, Gamis AS, Redell MS. Ligand-induced STAT3 signaling increases at relapse and is associated with outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Haematologica. 2015 Dec; 100(12):e496-500. PMID: 26294728; PMCID: PMC4666340.
      33. Fisher DG, Hess KL, Erlyana E, Reynolds GL, Cummins CA, Alonzo T. Comparison of Rapid Point-of-Care Tests for Detection of Antibodies to Hepatitis C Virus. Open Forum Infect Dis. 2015 Sep; 2(3):ofv101. PMID: 26269795; PMCID: PMC4531224.
      34. Vujkovic M, Attiyeh EF, Ries RE, Horn M, Goodman EK, Ding Y, Kavcic M, Alonzo T, Gerbing RB, Hirsch B, Raimondi S, Gamis AS, Meshinchi S, Aplenc R. Concordance of copy number alterations using a common analytic pipeline for genome-wide analysis of Illumina and Affymetrix genotyping data: a report from the Children's Oncology Group. Cancer Genet. 2015 Jul-Aug; 208(7-8):408-13. PMID: 26163103; PMCID: PMC4523450.
      35. Getz KD, Li Y, Alonzo T, Hall M, Gerbing RB, Sung L, Huang YS, Arnold S, Seif AE, Miller TP, Bagatell R, Fisher BT, Adamson PC, Gamis A, Keren R, Aplenc R. Comparison of in-patient costs for children treated on the AAML0531 clinical trial: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2015 Oct; 62(10):1775-81. PMID: 25946708; PMCID: PMC4546551.
      36. Johnston D, Gerbing R, Alonzo T, Aplenc R, Nagarajan R, Schulte F, Cullen P, Sung L. Patient-Reported Outcome Coordinator Did Not Improve Quality of Life Assessment Response Rates: A Report from the Children's Oncology Group. PLoS One. 2015; 10(4):e0125290. PMID: 25915772; PMCID: PMC4411136.
      37. Laszlo GS, Alonzo T, Gudgeon CJ, Harrington KH, Gerbing RB, Wang YC, Ries RE, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S, Walter RB. Multimerin-1 (MMRN1) as Novel Adverse Marker in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group. Clin Cancer Res. 2015 Jul 15; 21(14):3187-95. PMID: 25825478; PMCID: PMC4506237.
      38. Miller TP, Troxel AB, Li Y, Huang YS, Alonzo T, Gerbing RB, Hall M, Torp K, Fisher BT, Bagatell R, Seif AE, Sung L, Gamis A, Rubin D, Luger S, Aplenc R. Comparison of administrative/billing data to expected protocol-mandated chemotherapy exposure in children with acute myeloid leukemia: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2015 Jul; 62(7):1184-9. PMID: 25760019; PMCID: PMC4433587.
      39. Stieglitz E, Ward AF, Gerbing RB, Alonzo T, Arceci RJ, Liu YL, Emanuel PD, Widemann BC, Cheng JW, Jayaprakash N, Balis FM, Castleberry RP, Bunin NJ, Loh ML, Cooper TM. Phase II/III trial of a pre-transplant farnesyl transferase inhibitor in juvenile myelomonocytic leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2015 Apr; 62(4):629-36. PMID: 25704135; PMCID: PMC4339233.
      40. Stieglitz E, Troup CB, Gelston LC, Haliburton J, Chow ED, Yu KB, Akutagawa J, Taylor-Weiner AN, Liu YL, Wang YD, Beckman K, Emanuel PD, Braun BS, Abate A, Gerbing RB, Alonzo T, Loh ML. Subclonal mutations in SETBP1 confer a poor prognosis in juvenile myelomonocytic leukemia. Blood. 2015 Jan 15; 125(3):516-24. PMID: 25395418; PMCID: PMC4296011.
      41. Gamis AS, Alonzo T, Meshinchi S, Sung L, Gerbing RB, Raimondi SC, Hirsch BA, Kahwash SB, Heerema-McKenney A, Winter L, Glick K, Davies SM, Byron P, Smith FO, Aplenc R. Gemtuzumab ozogamicin in children and adolescents with de novo acute myeloid leukemia improves event-free survival by reducing relapse risk: results from the randomized phase III Children’s Oncology Group trial AAML0531. J Clin Oncol. 2014 Sep 20; 32(27):3021-32. PMID: 25092781; PMCID: PMC4162498.
      42. Ostronoff F, Othus M, Gerbing RB, Loken MR, Raimondi SC, Hirsch BA, Lange BJ, Petersdorf S, Radich J, Appelbaum FR, Gamis AS, Alonzo T, Meshinchi S. NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report. Blood. 2014 Oct 09; 124(15):2400-7. PMID: 25145343; PMCID: PMC4192751.
      43. Horton TM, Perentesis JP, Gamis AS, Alonzo T, Gerbing RB, Ballard J, Adlard K, Howard DS, Smith FO, Jenkins G, Kelder A, Schuurhuis GJ, Moscow JA. A Phase 2 study of bortezomib combined with either idarubicin/cytarabine or cytarabine/etoposide in children with relapsed, refractory or secondary acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2014 Oct; 61(10):1754-60. PMID: 24976003; PMCID: PMC4247259.
      44. Cooper TM, Alonzo T, Gerbing RB, Perentesis JP, Whitlock JA, Taub JW, Horton TM, Gamis AS, Meshinchi S, Loken MR, Razzouk BI. AAML0523: a report from the Children's Oncology Group on the efficacy of clofarabine in combination with cytarabine in pediatric patients with recurrent acute myeloid leukemia. Cancer. 2014 Aug 15; 120(16):2482-9. PMID: 24771494; PMCID: PMC4126862.
      45. Tarlock K, Alonzo T, Moraleda PP, Gerbing RB, Raimondi SC, Hirsch BA, Ravindranath Y, Lange B, Woods WG, Gamis AS, Meshinchi S. Acute myeloid leukaemia (AML) with t(6;9)(p23;q34) is associated with poor outcome in childhood AML regardless of FLT3-ITD status: a report from the Children's Oncology Group. Br J Haematol. 2014 Jul; 166(2):254-9. PMID: 24661089.
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      46. Laszlo GS, Ries RE, Gudgeon CJ, Harrington KH, Alonzo T, Gerbing RB, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S, Walter RB. High expression of suppressor of cytokine signaling-2 predicts poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Leuk Lymphoma. 2014 Dec; 55(12):2817-21. PMID: 24559289; PMCID: PMC4285350.
      47. Ringham BM, Alonzo T, Brinton JT, Kreidler SM, Munjal A, Muller KE, Glueck DH. Reducing decision errors in the paired comparison of the diagnostic accuracy of screening tests with Gaussian outcomes. BMC Med Res Methodol. 2014 Mar 05; 14:37. PMID: 24597517; PMCID: PMC4015908.
      48. Lee GE, Sung L, Fisher BT, Sullivan KE, McWilliams T, Tobias JW, Meshinchi S, Alonzo T, Gamis A, Aplenc R. Gene expression profiling to predict viridans group streptococcal and invasive fungal infection in pediatric acute myeloid leukemia: a brief report from the Children's Oncology Group. Acta Haematol. 2014; 131(3):167-9. PMID: 24217778; PMCID: PMC4443693.
      49. Moore AS, Alonzo T, Gerbing RB, Lange BJ, Heerema NA, Franklin J, Raimondi SC, Hirsch BA, Gamis AS, Meshinchi S. BIRC5 (survivin) splice variant expression correlates with refractory disease and poor outcome in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2014 Apr; 61(4):647-52. PMID: 24127439; PMCID: PMC4285339.
      50. Johnson SR, Godbert S, Perry P, Parsons P, Roberts L, Buchanan P, Larsen J, Alonzo T, Zinaman M. Accuracy of a home-based device for giving an early estimate of pregnancy duration compared with reference methods. Fertil Steril. 2013 Dec; 100(6):1635-41.e1. PMID: 24074759.
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      51. Woods WG, Franklin AR, Alonzo T, Gerbing RB, Donohue KA, Othus M, Horan J, Appelbaum FR, Estey EH, Bloomfield CD, Larson RA. Outcome of adolescents and young adults with acute myeloid leukemia treated on COG trials compared to CALGB and SWOG trials. Cancer. 2013 Dec 01; 119(23):4170-9. PMID: 24104597; PMCID: PMC3833872.
      52. Canner J, Alonzo T, Franklin J, Freyer DR, Gamis A, Gerbing RB, Lange BJ, Meshinchi S, Woods WG, Perentesis J, Horan J. Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients: a report from the Children's Oncology Group. Cancer. 2013 Dec 01; 119(23):4162-9. PMID: 24104395; PMCID: PMC4398142.
      53. Johnston DL, Alonzo T, Gerbing RB, Hirsch B, Heerema NA, Ravindranath Y, Woods WG, Lange BJ, Gamis AS, Raimondi SC. Outcome of pediatric patients with acute myeloid leukemia (AML) and -5/5q- abnormalities from five pediatric AML treatment protocols: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2013 Dec; 60(12):2073-8. PMID: 24039149.
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      54. Coenen EA, Zwaan CM, Reinhardt D, Harrison CJ, Haas OA, de Haas V, Mihál V, De Moerloose B, Jeison M, Rubnitz JE, Tomizawa D, Johnston D, Alonzo T, Hasle H, Auvrignon A, Dworzak M, Pession A, van der Velden VH, Swansbury J, Wong KF, Terui K, Savasan S, Winstanley M, Vaitkeviciene G, Zimmermann M, Pieters R, van den Heuvel-Eibrink MM. Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Munster AML-study group. Blood. 2013 Oct 10; 122(15):2704-13. PMID: 23974201; PMCID: PMC4314534.
      55. Kelly MJ, Horan JT, Alonzo T, Eapen M, Gerbing RB, He W, Lange BJ, Parsons SK, Woods WG. Comparable survival for pediatric acute myeloid leukemia with poor-risk cytogenetics following chemotherapy, matched related donor, or unrelated donor transplantation. Pediatr Blood Cancer. 2014 Feb; 61(2):269-75. PMID: 23955900; PMCID: PMC3919967.
      56. Ho PA, Alonzo T, Gerbing RB, Kuhn J, Pollard JA, Hirsch B, Raimondi SC, Gamis AS, Meshinchi S. The prognostic effect of high diagnostic WT1 gene expression in pediatric AML depends on WT1 SNP rs16754 status: report from the Children's Oncology Group. Pediatr Blood Cancer. 2014 Jan; 61(1):81-8. PMID: 23956224.
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      57. Ho PA, Alonzo T, Gerbing RB, Pollard JA, Hirsch B, Raimondi SC, Cooper T, Gamis AS, Meshinchi S. High EVI1 expression is associated with MLL rearrangements and predicts decreased survival in paediatric acute myeloid leukaemia: a report from the children's oncology group. Br J Haematol. 2013 Sep; 162(5):670-7. PMID: 23826732; PMCID: PMC3754879.
      58. Walter RB, Laszlo GS, Alonzo T, Gerbing RB, Levy S, Fitzgibbon MP, Gudgeon CJ, Ries RE, Harrington KH, Raimondi SC, Hirsch BA, Gamis AS, W McIntosh M, Meshinchi S. Significance of expression of ITGA5 and its splice variants in acute myeloid leukemia: a report from the Children's Oncology Group. Am J Hematol. 2013 Aug; 88(8):694-702. PMID: 23686445; PMCID: PMC3757130.
      59. Lacayo NJ, Alonzo T, Gayko U, Rosen DB, Westfall M, Purvis N, Putta S, Louie B, Hackett J, Cohen AC, Cesano A, Gerbing R, Ravindranath Y, Dahl GV, Gamis A, Meshinchi S. Development and validation of a single-cell network profiling assay-based classifier to predict response to induction therapy in paediatric patients with de novo acute myeloid leukaemia: a report from the Children's Oncology Group. Br J Haematol. 2013 Jul; 162(2):250-62. PMID: 23682827; PMCID: PMC4654575.
      60. Sung L, Aplenc R, Alonzo T, Gerbing RB, Lehrnbecher T, Gamis AS. Effectiveness of supportive care measures to reduce infections in pediatric AML: a report from the Children's Oncology Group. Blood. 2013 May 02; 121(18):3573-7. PMID: 23471307; PMCID: PMC3643758.
      61. Mortland L, Alonzo T, Walter RB, Gerbing RB, Mitra AK, Pollard JA, Loken MR, Hirsch B, Raimondi S, Franklin J, Pounds S, Cao X, Rubnitz JE, Ribeiro RC, Gamis A, Meshinchi S, Lamba JK. Clinical significance of CD33 nonsynonymous single-nucleotide polymorphisms in pediatric patients with acute myeloid leukemia treated with gemtuzumab-ozogamicin-containing chemotherapy. Clin Cancer Res. 2013 Mar 15; 19(6):1620-7. PMID: 23444229; PMCID: PMC3602123.
      62. Teuffel O, Leibundgut K, Lehrnbecher T, Alonzo T, Beyene J, Sung L. Anthracyclines during induction therapy in acute myeloid leukaemia: a systematic review and meta-analysis. Br J Haematol. 2013 Apr; 161(2):192-203. PMID: 23398482.
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      63. Cooper TM, Razzouk BI, Gerbing R, Alonzo T, Adlard K, Raetz E, Gamis AS, Perentesis J, Whitlock JA. Phase I/II trial of clofarabine and cytarabine in children with relapsed/refractory acute lymphoblastic leukemia (AAML0523): a report from the Children's Oncology Group. Pediatr Blood Cancer. 2013 Jul; 60(7):1141-7. PMID: 23335239; PMCID: PMC4605828.
      64. Gamis AS, Alonzo T, Perentesis JP, Meshinchi S. Children's Oncology Group's 2013 blueprint for research: acute myeloid leukemia. Pediatr Blood Cancer. 2013 Jun; 60(6):964-71. PMID: 23255301; PMCID: PMC4605815.
      65. Redell MS, Ruiz MJ, Gerbing RB, Alonzo T, Lange BJ, Tweardy DJ, Meshinchi S. FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report. Blood. 2013 Feb 14; 121(7):1083-93. PMID: 23243289; PMCID: PMC3575754.
      66. Nakas CT, Dalrymple-Alford JC, Anderson TJ, Alonzo T. Generalization of Youden index for multiple-class classification problems applied to the assessment of externally validated cognition in Parkinson disease screening. Stat Med. 2013 Mar 15; 32(6):995-1003. PMID: 22949169.
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      67. Sung L, Aplenc R, Alonzo T, Gerbing RB, Gamis AS. Predictors and short-term outcomes of hyperleukocytosis in children with acute myeloid leukemia: a report from the Children's Oncology Group. Haematologica. 2012 Nov; 97(11):1770-3. PMID: 22801969; PMCID: PMC3487455.
      68. Gudgeon CJ, Harrington KH, Laszlo GS, Alonzo T, Gerbing RB, Gamis AS, Raimondi SC, Hirsch BA, Meshinchi S, Walter RB. High expression of neutrophil elastase predicts improved survival in pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Leuk Lymphoma. 2013 Jan; 54(1):202-4. PMID: 22680764; PMCID: PMC3757129.
      69. Loken MR, Alonzo T, Pardo L, Gerbing RB, Raimondi SC, Hirsch BA, Ho PA, Franklin J, Cooper TM, Gamis AS, Meshinchi S. Residual disease detected by multidimensional flow cytometry signifies high relapse risk in patients with de novo acute myeloid leukemia: a report from Children's Oncology Group. Blood. 2012 Aug 23; 120(8):1581-8. PMID: 22649108; PMCID: PMC3429302.
      70. Rochowski A, Olson SB, Alonzo T, Gerbing RB, Lange BJ, Alter BP. Patients with Fanconi anemia and AML have different cytogenetic clones than de novo cases of AML. Pediatr Blood Cancer. 2012 Nov; 59(5):922-4. PMID: 22517793; PMCID: PMC3407278.
      71. Inácio V, González-Manteiga W, Febrero-Bande M, Gude F, Alonzo T, Cadarso-Suárez C. Extending induced ROC methodology to the functional context. Biostatistics. 2012 Sep; 13(4):594-608. PMID: 22474123.
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      72. Sorrell AD, Alonzo T, Hilden JM, Gerbing RB, Loew TW, Hathaway L, Barnard D, Taub JW, Ravindranath Y, Smith FO, Arceci RJ, Woods WG, Gamis AS. Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group. Cancer. 2012 Oct 01; 118(19):4806-14. PMID: 22392565; PMCID: PMC3879144.
      73. Chaleff S, Hurwitz CA, Chang M, Dahl G, Alonzo T, Weinstein H. Phase II study of 2-chlorodeoxyadenosine plus idarubicin for children with acute myeloid leukaemia in first relapse: a paediatric oncology group study. Br J Haematol. 2012 Mar; 156(5):649-55. PMID: 22512017.
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      74. Pollard JA, Alonzo T, Loken M, Gerbing RB, Ho PA, Bernstein ID, Raimondi SC, Hirsch B, Franklin J, Walter RB, Gamis A, Meshinchi S. Correlation of CD33 expression level with disease characteristics and response to gemtuzumab ozogamicin containing chemotherapy in childhood AML. Blood. 2012 Apr 19; 119(16):3705-11. PMID: 22378848; PMCID: PMC3335378.
      75. Sung L, Buxton A, Gamis A, Woods WG, Alonzo T. Life-threatening and fatal infections in children with acute myeloid leukemia: a report from the Children's Oncology Group. J Pediatr Hematol Oncol. 2012 Jan; 34(1):e30-5. PMID: 22052170; PMCID: PMC4490686.
      76. Inácio V, Turkman AA, Nakas CT, Alonzo T. Nonparametric Bayesian estimation of the three-way receiver operating characteristic surface. Biom J. 2011 Nov; 53(6):1011-24. PMID: 22069202.
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      77. Rochowski A, Rosenberg PS, Alonzo T, Gerbing RB, Lange BJ, Alter BP. Estimation of the prevalence of Fanconi anemia among patients with de novo acute myelogenous leukemia who have poor recovery from chemotherapy. Leuk Res. 2012 Jan; 36(1):29-31. PMID: 21974856; PMCID: PMC4008327.
      78. Ho PA, Kopecky KJ, Alonzo T, Gerbing RB, Miller KL, Kuhn J, Zeng R, Ries RE, Raimondi SC, Hirsch BA, Oehler V, Hurwitz CA, Franklin JL, Gamis AS, Petersdorf SH, Anderson JE, Godwin JE, Reaman GH, Willman CL, Bernstein ID, Radich JP, Appelbaum FR, Stirewalt DL, Meshinchi S. Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG. Blood. 2011 Oct 27; 118(17):4561-6. PMID: 21873548; PMCID: PMC3208275.
      79. Gamis AS, Alonzo T, Gerbing RB, Hilden JM, Sorrell AD, Sharma M, Loew TW, Arceci RJ, Barnard D, Doyle J, Massey G, Perentesis J, Ravindranath Y, Taub J, Smith FO. Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971. Blood. 2011 Dec 22; 118(26):6752-9; quiz 6996. PMID: 21849481; PMCID: PMC3245202.
      80. Cooper TM, Franklin J, Gerbing RB, Alonzo T, Hurwitz C, Raimondi SC, Hirsch B, Smith FO, Mathew P, Arceci RJ, Feusner J, Iannone R, Lavey RS, Meshinchi S, Gamis A. AAML03P1, a pilot study of the safety of gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia: a report from the Children's Oncology Group. Cancer. 2012 Feb 01; 118(3):761-9. PMID: 21766293.
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      81. Lange BJ, Yang RK, Gan J, Hank JA, Sievers EL, Alonzo T, Gerbing RB, Sondel PM. Soluble interleukin-2 receptor a activation in a Children's Oncology Group randomized trial of interleukin-2 therapy for pediatric acute myeloid leukemia. Pediatr Blood Cancer. 2011 Sep; 57(3):398-405. PMID: 21681921; PMCID: PMC3172052.
      82. Mathew P, Gerbing R, Alonzo T, Wallas T, Gong JZ, Jasty R, Jorstad DT, Raimondi SC, Chavez CM, Eisenberg NL, Hirsch B, Gamis A, Smith FO, Arceci RJ. A phase II study of amifostine in children with myelodysplastic syndrome: a report from the Children's Oncology Group study (AAML0121). Pediatr Blood Cancer. 2011 Dec 15; 57(7):1230-2. PMID: 21681928.
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      83. Braun TM, Alonzo T. Beyond the 3+3 method: expanded algorithms for dose- escalation in Phase I oncology trials of two agents. Clin Trials. 2011 Jun; 8(3):247-59. PMID: 21730075.
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      84. Johnston DL, Alonzo T, Gerbing RB, Lange BJ, Woods WG. Superior outcome of pediatric acute myeloid leukemia patients with orbital and CNS myeloid sarcoma: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2012 Apr; 58(4):519-24. PMID: 21618422; PMCID: PMC3165066.
      85. Coenen EA, Raimondi SC, Harbott J, Zimmermann M, Alonzo T, Auvrignon A, Beverloo HB, Chang M, Creutzig U, Dworzak MN, Forestier E, Gibson B, Hasle H, Harrison CJ, Heerema NA, Kaspers GJ, Leszl A, Litvinko N, Lo Nigro L, Morimoto A, Perot C, Reinhardt D, Rubnitz JE, Smith FO, Stary J, Stasevich I, Strehl S, Taga T, Tomizawa D, Webb D, Zemanova Z, Pieters R, Zwaan CM, van den Heuvel-Eibrink MM. Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study. Blood. 2011 Jun 30; 117(26):7102-11. PMID: 21551233; PMCID: PMC3143552.
      86. Buyse M, Squifflet P, Lange BJ, Alonzo T, Larson RA, Kolitz JE, George SL, Bloomfield CD, Castaigne S, Chevret S, Blaise D, Maraninchi D, Lucchesi KJ, Burzykowski T. Individual patient data meta-analysis of randomized trials evaluating IL-2 monotherapy as remission maintenance therapy in acute myeloid leukemia. Blood. 2011 Jun 30; 117(26):7007-13. PMID: 21518931; PMCID: PMC3539044.
      87. Ho PA, Kutny MA, Alonzo T, Gerbing RB, Joaquin J, Raimondi SC, Gamis AS, Meshinchi S. Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2011 Aug; 57(2):204-9. PMID: 21504050; PMCID: PMC3115394.
      88. Alonzo T, Brinton JT, Ringham BM, Glueck DH. Bias in estimating accuracy of a binary screening test with differential disease verification. Stat Med. 2011 Jul 10; 30(15):1852-64. PMID: 21495059; PMCID: PMC3115446.
      89. Champagne MA, Fu CH, Chang M, Chen H, Gerbing RB, Alonzo T, Cooley LD, Heerema NA, Oehler V, Wood C, French ME, Arceci RJ, Smith FO, Bernstein ML. Higher dose imatinib for children with de novo chronic phase chronic myelogenous leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2011 Jul 15; 57(1):56-62. PMID: 21465636.
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      90. Redell MS, Ruiz MJ, Alonzo T, Gerbing RB, Tweardy DJ. Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor. Blood. 2011 May 26; 117(21):5701-9. PMID: 21447830; PMCID: PMC3110027.
      91. Cremer M, Conlisk E, Maza M, Bullard K, Peralta E, Siedhoff M, Alonzo T, Felix J. Adequacy of visual inspection with acetic acid in women of advancing age. Int J Gynaecol Obstet. 2011 Apr; 113(1):68-71. PMID: 21272884.
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      92. Ho PA, Kuhn J, Gerbing RB, Pollard JA, Zeng R, Miller KL, Heerema NA, Raimondi SC, Hirsch BA, Franklin JL, Lange B, Gamis AS, Alonzo T, Meshinchi S. WT1 synonymous single nucleotide polymorphism rs16754 correlates with higher mRNA expression and predicts significantly improved outcome in favorable-risk pediatric acute myeloid leukemia: a report from the children's oncology group. J Clin Oncol. 2011 Feb 20; 29(6):704-11. PMID: 21189390; PMCID: PMC3056655.
      93. Nakas CT, Alonzo T, Yiannoutsos CT. Accuracy and cut-off point selection in three-class classification problems using a generalization of the Youden index. Stat Med. 2010 Dec 10; 29(28):2946-55. PMID: 20809485; PMCID: PMC2991472.
      94. Cremer M, Bullard KA, Mosley RM, Weiselberg C, Molaei M, Lerner V, Alonzo T. Immediate vs. delayed post-abortal copper T 380A IUD insertion in cases over 12 weeks of gestation. Contraception. 2011 Jun; 83(6):522-7. PMID: 21570549.
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      95. Cremer M, Bullard K, Maza M, Peralta E, Moore E, Garcia L, Masch R, Lerner V, Alonzo T, Felix J. Cytology versus visual inspection with acetic acid among women treated previously with cryotherapy in a low-resource setting. Int J Gynaecol Obstet. 2010 Dec; 111(3):249-52. PMID: 20801447.
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      96. Johnston DL, Alonzo T, Gerbing RB, Lange BJ, Woods WG. The presence of central nervous system disease at diagnosis in pediatric acute myeloid leukemia does not affect survival: a Children's Oncology Group study. Pediatr Blood Cancer. 2010 Sep; 55(3):414-20. PMID: 20658610; PMCID: PMC2990693.
      97. Phillips CL, Gerbing R, Alonzo T, Perentesis JP, Harley IT, Meshinchi S, Bhatla D, Radloff G, Davies SM. MDM2 polymorphism increases susceptibility to childhood acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2010 Aug; 55(2):248-53. PMID: 20582981; PMCID: PMC2915901.
      98. Walter RB, Alonzo T, Gerbing RB, Ho PA, Smith FO, Raimondi SC, Hirsch BA, Gamis AS, Franklin JL, Hurwitz CA, Loken MR, Meshinchi S. High expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology group. J Clin Oncol. 2010 Jun 10; 28(17):2831-8. PMID: 20421533; PMCID: PMC2903318.
      99. Ho PA, Zeng R, Alonzo T, Gerbing RB, Miller KL, Pollard JA, Stirewalt DL, Heerema NA, Raimondi SC, Hirsch B, Franklin JL, Lange B, Meshinchi S. Prevalence and prognostic implications of WT1 mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group. Blood. 2010 Aug 05; 116(5):702-10. PMID: 20413658; PMCID: PMC2918327.
      100. Cremer ML, Alonzo T, Alspach AE, Shulman IA, Cernosek S, Tsai S, Kalichanda N, Felix JC. Diagnostic reproducibility of cervical intraepithelial neoplasia 3 and atrophy in menopausal women on hematoxylin and eosin, Ki-67, and p16 stained slides. J Low Genit Tract Dis. 2010 Apr; 14(2):108-12. PMID: 20354418.
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      101. Ringham BM, Alonzo T, Grunwald GK, Glueck DH. Estimates of sensitivity and specificity can be biased when reporting the results of the second test in a screening trial conducted in series. BMC Med Res Methodol. 2010 Jan 11; 10:3. PMID: 20064254; PMCID: PMC2819240.
      102. Pollard JA, Alonzo T, Gerbing RB, Ho PA, Zeng R, Ravindranath Y, Dahl G, Lacayo NJ, Becton D, Chang M, Weinstein HJ, Hirsch B, Raimondi SC, Heerema NA, Woods WG, Lange BJ, Hurwitz C, Arceci RJ, Radich JP, Bernstein ID, Heinrich MC, Meshinchi S. Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML. Blood. 2010 Mar 25; 115(12):2372-9. PMID: 20056794; PMCID: PMC2845895.
      103. Cremer ML, Peralta EI, Dheming SG, Jimenez ME, Davis-Dao CA, Alonzo T, Blumenthal PD, Felix JC. Digital assessment of the reproductive tract versus colposcopy for directing biopsies in women with abnormal Pap smears. J Low Genit Tract Dis. 2010 Jan; 14(1):5-10. PMID: 20040830.
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      104. Gregory J, Kim H, Alonzo T, Gerbing R, Woods W, Weinstein H, Shepherd L, Schiffer C, Appelbaum F, Willman C, Wiernik P, Rowe J, Tallman M, Feusner J. Treatment of children with acute promyelocytic leukemia: results of the first North American Intergroup trial INT0129. Pediatr Blood Cancer. 2009 Dec; 53(6):1005-10. PMID: 19743516; PMCID: PMC3508725.
      105. Noronha SA, Farrar JE, Alonzo T, Gerbing RB, Lacayo NJ, Dahl GV, Ravindranath Y, Arceci RJ, Loeb DM. WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2009 Dec; 53(6):1136-9. PMID: 19618455; PMCID: PMC2926132.
      106. Alonzo T, Nakas CT, Papadopoulos NT, Papachristos DP. A receiver operating characteristic analysis approach for the assessment of the separation of female Mediterranean fruit fly (Diptera: Tephritidae) oviposition distributions. J Econ Entomol. 2009 Oct; 102(5):1985-91. PMID: 19886466.
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      107. Khemani RG, Conti D, Alonzo T, Bart RD, Newth CJ. Effect of tidal volume in children with acute hypoxemic respiratory failure. Intensive Care Med. 2009 Aug; 35(8):1428-37. PMID: 19533092.
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      108. Balgobind BV, Raimondi SC, Harbott J, Zimmermann M, Alonzo T, Auvrignon A, Beverloo HB, Chang M, Creutzig U, Dworzak MN, Forestier E, Gibson B, Hasle H, Harrison CJ, Heerema NA, Kaspers GJ, Leszl A, Litvinko N, Nigro LL, Morimoto A, Perot C, Pieters R, Reinhardt D, Rubnitz JE, Smith FO, Stary J, Stasevich I, Strehl S, Taga T, Tomizawa D, Webb D, Zemanova Z, Zwaan CM, van den Heuvel-Eibrink MM. Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study. Blood. 2009 Sep 17; 114(12):2489-96. PMID: 19528532; PMCID: PMC2927031.
      109. Alonzo T. Comparing accuracy in an unpaired post-market device study with incomplete disease assessment. Biom J. 2009 Jun; 51(3):491-503. PMID: 19572317.
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      110. Cremer M, Holland E, Adams B, Klausner D, Nichols S, Ram RS, Alonzo T. Adolescent comprehension of emergency contraception in New York City. Obstet Gynecol. 2009 Apr; 113(4):840-4. PMID: 19305328.
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      111. Alonzo T, Nakas CT, Yiannoutsos CT, Bucher S. A comparison of tests for restricted orderings in the three-class case. Stat Med. 2009 Mar 30; 28(7):1144-58. PMID: 19156672.
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      112. Ho PA, Alonzo T, Gerbing RB, Pollard J, Stirewalt DL, Hurwitz C, Heerema NA, Hirsch B, Raimondi SC, Lange B, Franklin JL, Radich JP, Meshinchi S. Prevalence and prognostic implications of CEBPA mutations in pediatric acute myeloid leukemia (AML): a report from the Children's Oncology Group. Blood. 2009 Jun 25; 113(26):6558-66. PMID: 19304957; PMCID: PMC2943755.
      113. Sung L, Gamis A, Alonzo T, Buxton A, Britton K, Deswarte-Wallace J, Woods WG. Infections and association with different intensity of chemotherapy in children with acute myeloid leukemia. Cancer. 2009 Mar 01; 115(5):1100-8. PMID: 19156894; PMCID: PMC2677372.
      114. Shaw PA, Pepe MS, Alonzo T, Etzioni R. Methods for Assessing Improvement in Specificity when a Biomarker is Combined with a Standard Screening Test. Stat Biopharm Res. 2009 Feb 01; 1(1):18-25. PMID: 20054437.
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      115. Glueck DH, Lamb MM, O'Donnell CI, Ringham BM, Brinton JT, Muller KE, Lewin JM, Alonzo T, Pisano ED. Bias in trials comparing paired continuous tests can cause researchers to choose the wrong screening modality. BMC Med Res Methodol. 2009 Jan 20; 9:4. PMID: 19154609; PMCID: PMC2657218.
      116. Sung L, Alonzo T, Gerbing RB, Aplenc R, Lange BJ, Woods WG, Feusner J, Franklin J, Patterson MJ, Gamis AS. Respiratory syncytial virus infections in children with acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2008 Dec; 51(6):784-6. PMID: 18680152; PMCID: PMC2727468.
      117. Mehta PA, Gerbing RB, Alonzo T, Elliott JS, Zamzow TA, Combs M, Stover E, Ross JA, Perentesis JP, Meschinchi S, Lange BJ, Davies SM. FAS promoter polymorphism: outcome of childhood acute myeloid leukemia. A children's oncology group report. Clin Cancer Res. 2008 Dec 01; 14(23):7896-9. PMID: 19047119; PMCID: PMC2787450.
      118. Bhatla D, Gerbing RB, Alonzo T, Conner H, Ross JA, Meshinchi S, Zhai X, Zamzow T, Mehta PA, Geiger H, Perentesis J, Davies SM. Cytidine deaminase genotype and toxicity of cytosine arabinoside therapy in children with acute myeloid leukemia. Br J Haematol. 2009 Feb; 144(3):388-94. PMID: 19036079; PMCID: PMC3083240.
      119. Horan JT, Alonzo T, Lyman GH, Gerbing RB, Lange BJ, Ravindranath Y, Becton D, Smith FO, Woods WG. Impact of disease risk on efficacy of matched related bone marrow transplantation for pediatric acute myeloid leukemia: the Children's Oncology Group. J Clin Oncol. 2008 Dec 10; 26(35):5797-801. PMID: 18955460; PMCID: PMC2645105.
      120. Anglim PP, Alonzo T, Laird-Offringa IA. DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update. Mol Cancer. 2008 Oct 23; 7:81. PMID: 18947422; PMCID: PMC2585582.
      121. Khemani RG, Bart RD, Alonzo T, Hatzakis G, Hallam D, Newth CJ. Disseminated intravascular coagulation score is associated with mortality for children with shock. Intensive Care Med. 2009 Feb; 35(2):327-33. PMID: 18802683.
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      122. Aplenc R, Alonzo T, Gerbing RB, Lange BJ, Hurwitz CA, Wells RJ, Bernstein I, Buckley P, Krimmel K, Smith FO, Sievers EL, Arceci RJ. Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group. J Clin Oncol. 2008 May 10; 26(14):2390-3295. PMID: 18467731; PMCID: PMC4558626.
      123. Meshinchi S, Stirewalt DL, Alonzo T, Boggon TJ, Gerbing RB, Rocnik JL, Lange BJ, Gilliland DG, Radich JP. Structural and numerical variation of FLT3/ITD in pediatric AML. Blood. 2008 May 15; 111(10):4930-3. PMID: 18305215; PMCID: PMC2384125.
      124. Cibas ES, Alonzo T, Austin RM, Bolick DR, Glant MD, Henry MR, Moriarty AT, Molina JT, Rushing L, Slowman SD, Torno R, Eisenhut CC. The MonoPrep Pap test for the detection of cervical cancer and its precursors. Part I: results of a multicenter clinical trial. Am J Clin Pathol. 2008 Feb; 129(2):193-201. PMID: 18208798.
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      125. Castellino SM, Alonzo T, Buxton A, Gold S, Lange BJ, Woods WG. Outcomes in childhood AML in the absence of transplantation in first remission--Children's Cancer Group (CCG) studies 2891 and CCG 213. Pediatr Blood Cancer. 2008 Jan; 50(1):9-16. PMID: 17252564.
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      126. Lange BJ, Smith FO, Feusner J, Barnard DR, Dinndorf P, Feig S, Heerema NA, Arndt C, Arceci RJ, Seibel N, Weiman M, Dusenbery K, Shannon K, Luna-Fineman S, Gerbing RB, Alonzo T. Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: a report from the children's oncology group. Blood. 2008 Feb 01; 111(3):1044-53. PMID: 18000167; PMCID: PMC2214754.
      127. Braun TM, Alonzo T. A modified sign test for comparing paired ROC curves. Biostatistics. 2008 Apr; 9(2):364-72. PMID: 17925302.
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      128. Alonzo T, Nakas CT. Comparison of ROC umbrella volumes with an application to the assessment of lung cancer diagnostic markers. Biom J. 2007 Aug; 49(5):654-64. PMID: 17726716.
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      129. Sung L, Lange BJ, Gerbing RB, Alonzo T, Feusner J. Microbiologically documented infections and infection-related mortality in children with acute myeloid leukemia. Blood. 2007 Nov 15; 110(10):3532-9. PMID: 17660380.
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      130. Barnard DR, Alonzo T, Gerbing RB, Lange B, Woods WG. Comparison of childhood myelodysplastic syndrome, AML FAB M6 or M7, CCG 2891: report from the Children's Oncology Group. Pediatr Blood Cancer. 2007 Jul; 49(1):17-22. PMID: 16856158.
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      131. Nakas CT, Alonzo T. ROC graphs for assessing the ability of a diagnostic marker to detect three disease classes with an umbrella ordering. Biometrics. 2007 Jun; 63(2):603-9. PMID: 17688513.
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      132. Sposto R, London WB, Alonzo T. Criteria for optimizing prognostic risk groups in pediatric cancer: analysis of data from the Children's Oncology Group. J Clin Oncol. 2007 May 20; 25(15):2070-7. PMID: 17513812.
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      133. Brown P, McIntyre E, Rau R, Meshinchi S, Lacayo N, Dahl G, Alonzo T, Chang M, Arceci RJ, Small D. The incidence and clinical significance of nucleophosmin mutations in childhood AML. Blood. 2007 Aug 01; 110(3):979-85. PMID: 17440048; PMCID: PMC1924773.
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      135. Alonzo T, Siegmund KD. Statistical methods for evaluating DNA methylation as a marker for early detection or prognosis. Dis Markers. 2007; 23(1-2):113-20. PMID: 17325431; PMCID: PMC3850861.
      136. Alonzo T, Pepe MS. Development and evaluation of classifiers. Methods Mol Biol. 2007; 404:89-116. PMID: 18450047.
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      137. Barbaric D, Alonzo T, Gerbing RB, Meshinchi S, Heerema NA, Barnard DR, Lange BJ, Woods WG, Arceci RJ, Smith FO. Minimally differentiated acute myeloid leukemia (FAB AML-M0) is associated with an adverse outcome in children: a report from the Children's Oncology Group, studies CCG-2891 and CCG-2961. Blood. 2007 Mar 15; 109(6):2314-21. PMID: 17158236; PMCID: PMC1852193.
      138. Meshinchi S, Alonzo T, Stirewalt DL, Zwaan M, Zimmerman M, Reinhardt D, Kaspers GJ, Heerema NA, Gerbing R, Lange BJ, Radich JP. Clinical implications of FLT3 mutations in pediatric AML. Blood. 2006 Dec 01; 108(12):3654-61. PMID: 16912228; PMCID: PMC1895470.
      139. Meshinchi S, Arceci RJ, Sanders JE, Smith FO, Woods WB, Radich JP, Alonzo T. Role of allogeneic stem cell transplantation in FLT3/ITD-positive AML. Blood. 2006 Jul 01; 108(1):400; author reply 400-1. PMID: 16790584.
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      140. Pollard JA, Alonzo T, Gerbing RB, Woods WG, Lange BJ, Sweetser DA, Radich JP, Bernstein ID, Meshinchi S. FLT3 internal tandem duplication in CD34+/CD33- precursors predicts poor outcome in acute myeloid leukemia. Blood. 2006 Oct 15; 108(8):2764-9. PMID: 16809615; PMCID: PMC1895585.
      141. Alonzo T, Kittelson JM. A novel design for estimating relative accuracy of screening tests when complete disease verification is not feasible. Biometrics. 2006 Jun; 62(2):605-12. PMID: 16918926.
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      142. Aplenc R, Alonzo T, Gerbing RB, Smith FO, Meshinchi S, Ross JA, Perentesis J, Woods WG, Lange BJ, Davies SM. Ethnicity and survival in childhood acute myeloid leukemia: a report from the Children's Oncology Group. Blood. 2006 Jul 01; 108(1):74-80. PMID: 16537811; PMCID: PMC1895824.
      143. Brumback LC, Pepe MS, Alonzo T. Using the ROC curve for gauging treatment effect in clinical trials. Stat Med. 2006 Feb 28; 25(4):575-90. PMID: 16220481.
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      144. Johnston DL, Alonzo T, Gerbing RB, Lange BJ, Woods WG. Risk factors and therapy for isolated central nervous system relapse of pediatric acute myeloid leukemia. J Clin Oncol. 2005 Dec 20; 23(36):9172-8. PMID: 16361619.
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      145. Alonzo T. Standards for reporting prognostic tumor marker studies. J Clin Oncol. 2005 Dec 20; 23(36):9053-4. PMID: 16301590.
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      146. Mehta PA, Alonzo T, Gerbing RB, Elliott JS, Wilke TA, Kennedy RJ, Ross JA, Perentesis JP, Lange BJ, Davies SM. XPD Lys751Gln polymorphism in the etiology and outcome of childhood acute myeloid leukemia: a Children's Oncology Group report. Blood. 2006 Jan 01; 107(1):39-45. PMID: 16150943.
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      147. Alonzo T, Wells RJ, Woods WG, Lange B, Gerbing RB, Buxton AB, Neudorf S, Sanders J, Smith FO, Feig SA. Postremission therapy for children with acute myeloid leukemia: the children's cancer group experience in the transplant era. Leukemia. 2005 Jun; 19(6):965-70. PMID: 15830007.
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      148. Alonzo T. Verification bias-corrected estimators of the relative true and false positive rates of two binary screening tests. Stat Med. 2005 Feb 15; 24(3):403-17. PMID: 15543634.
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      149. Lange BJ, Gerbing RB, Feusner J, Skolnik J, Sacks N, Smith FO, Alonzo T. Mortality in overweight and underweight children with acute myeloid leukemia. JAMA. 2005 Jan 12; 293(2):203-11. PMID: 15644547.
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      150. Tse W, Meshinchi S, Alonzo T, Stirewalt DL, Gerbing RB, Woods WG, Appelbaum FR, Radich JP. Elevated expression of the AF1q gene, an MLL fusion partner, is an independent adverse prognostic factor in pediatric acute myeloid leukemia. Blood. 2004 Nov 15; 104(10):3058-63. PMID: 15217837.
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      151. Brown P, Meshinchi S, Levis M, Alonzo T, Gerbing R, Lange B, Arceci R, Small D. Pediatric AML primary samples with FLT3/ITD mutations are preferentially killed by FLT3 inhibition. Blood. 2004 Sep 15; 104(6):1841-9. PMID: 15166029.
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      152. Neudorf S, Sanders J, Kobrinsky N, Alonzo T, Buxton AB, Gold S, Barnard DR, Wallace JD, Kalousek D, Lange BJ, Woods WG. Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival. Blood. 2004 May 15; 103(10):3655-61. PMID: 14751924.
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      153. Alonzo T, Braun TM, Moskowitz CS. Small sample estimation of relative accuracy for binary screening tests. Stat Med. 2004 Jan 15; 23(1):21-34. PMID: 14695637.
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      154. Lange BJ, Dinndorf P, Smith FO, Arndt C, Barnard D, Feig S, Feusner J, Seibel N, Weiman M, Aplenc R, Gerbing R, Alonzo T. Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941. J Clin Oncol. 2004 Jan 01; 22(1):150-6. PMID: 14701777.
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      155. Dusenbery KE, Howells WB, Arthur DC, Alonzo T, Lee JW, Kobrinsky N, Barnard DR, Wells RJ, Buckley JD, Lange BJ, Woods WG. Extramedullary leukemia in children with newly diagnosed acute myeloid leukemia: a report from the Children's Cancer Group. J Pediatr Hematol Oncol. 2003 Oct; 25(10):760-8. PMID: 14528097.
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      156. Wells RJ, Adams MT, Alonzo T, Arceci RJ, Buckley J, Buxton AB, Dusenbery K, Gamis A, Masterson M, Vik T, Warkentin P, Whitlock JA. Mitoxantrone and cytarabine induction, high-dose cytarabine, and etoposide intensification for pediatric patients with relapsed or refractory acute myeloid leukemia: Children's Cancer Group Study 2951. J Clin Oncol. 2003 Aug 01; 21(15):2940-7. PMID: 12885813.
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      157. Casillas JN, Woods WG, Hunger SP, McGavran L, Alonzo T, Feig SA. Prognostic implications of t(10;11) translocations in childhood acute myelogenous leukemia: a report from the Children's Cancer Group. J Pediatr Hematol Oncol. 2003 Aug; 25(8):594-600. PMID: 12902910.
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      158. Gamis AS, Woods WG, Alonzo T, Buxton A, Lange B, Barnard DR, Gold S, Smith FO. Increased age at diagnosis has a significantly negative effect on outcome in children with Down syndrome and acute myeloid leukemia: a report from the Children's Cancer Group Study 2891. J Clin Oncol. 2003 Sep 15; 21(18):3415-22. PMID: 12885836.
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      159. Meshinchi S, Stirewalt DL, Alonzo T, Zhang Q, Sweetser DA, Woods WG, Bernstein ID, Arceci RJ, Radich JP. Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia. Blood. 2003 Aug 15; 102(4):1474-9. PMID: 12702504.
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      160. Alonzo T, Pepe MS, Lumley T. Estimating disease prevalence in two-phase studies. Biostatistics. 2003 Apr; 4(2):313-26. PMID: 12925524.
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      161. Sievers EL, Lange BJ, Alonzo T, Gerbing RB, Bernstein ID, Smith FO, Arceci RJ, Woods WG, Loken MR. Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia. Blood. 2003 May 01; 101(9):3398-406. PMID: 12506020.
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      162. Alonzo T, Kobrinsky NL, Aledo A, Lange BJ, Buxton AB, Woods WG. Impact of granulocyte colony-stimulating factor use during induction for acute myelogenous leukemia in children: a report from the Children's Cancer Group. J Pediatr Hematol Oncol. 2002 Nov; 24(8):627-35. PMID: 12439034.
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      163. Alonzo T, Pepe MS. Distribution-free ROC analysis using binary regression techniques. Biostatistics. 2002 Sep; 3(3):421-32. PMID: 12933607.
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      164. Chen AR, Alonzo T, Woods WG, Arceci RJ. Current controversies: which patients with acute myeloid leukaemia should receive a bone marrow transplantation?--an American view. Br J Haematol. 2002 Aug; 118(2):378-84. PMID: 12139721.
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      165. Barnard DR, Lange B, Alonzo T, Buckley J, Kobrinsky JN, Gold S, Neudorf S, Sanders J, Burden L, Woods WG. Acute myeloid leukemia and myelodysplastic syndrome in children treated for cancer: comparison with primary presentation. Blood. 2002 Jul 15; 100(2):427-34. PMID: 12091332.
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      166. Alonzo T, Pepe MS, Moskowitz CS. Sample size calculations for comparative studies of medical tests for detecting presence of disease. Stat Med. 2002 Mar 30; 21(6):835-52. PMID: 11870820.
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      167. Woods WG, Barnard DR, Alonzo T, Buckley JD, Kobrinsky N, Arthur DC, Sanders J, Neudorf S, Gold S, Lange BJ. Prospective study of 90 children requiring treatment for juvenile myelomonocytic leukemia or myelodysplastic syndrome: a report from the Children's Cancer Group. J Clin Oncol. 2002 Jan 15; 20(2):434-40. PMID: 11786571.
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