Timothy J Triche, MD, PhD

Title(s)Professor of Pathology
SchoolKeck School of Medicine of Usc
AddressCHL Mail Stop 43
Off Campus
Los Angeles CA 90089
Phone+1 323 361 4516
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    My research focuses on genetic aspects of cancer biology and their biologic consequences. Current research emphasizes whole genome approaches to gene expression profiling and genomic polymorphisms using DNA microarrays and software developed by our group to analyze this data. Laboratory studies typically utilize tumor cell lines expressing transfected genes, or with silenced genes. Gene targets and biologically active small molecules are often analyzed in biologic context by these same methods. Clinical correlative studies utilize tumor tissue with linked clinical data. Recently, these methods have been applied to studies of age related macular degeneration, as part of the Beckman Macular Research Center at the Doheny Eye Institute, Keck School of Medicine.

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    Collapse Research Activities and Funding
    Integrated radiomic and liquid biopsy monitoring in SWOG S1802: A phase 3 therapeutic trial for metastatic prostate cancer
    NIH R01CA257610Feb 9, 2021 - Jan 31, 2026
    Role: Co-Principal Investigator
    NV103: Antibody Conjugated Nanoparticle for Ewing Sarcoma Targeted Therapy
    NIH R44CA233128Sep 14, 2018 - Apr 30, 2021
    Role: Co-Principal Investigator
    Nanoparticle Delivery System for Ewing Sarcoma Treatment
    NIH R41CA203457Apr 15, 2016 - Mar 31, 2018
    Role: Co-Principal Investigator
    Translation of Predictive Cancer Biomarkers into Clinical Practice
    NIH RC2CA148216Sep 29, 2009 - Aug 31, 2012
    Role: Co-Principal Investigator
    Diagnostic and Prognostic Sarcoma Signatures
    NIH U01CA114757Sep 27, 2005 - May 31, 2010
    Role: Principal Investigator
    GENE EXPRESSION IN SARCOMAS OF CHILDHOOD AND ADOLESCENCE
    NIH U01CA088199Sep 20, 2000 - Jan 31, 2007
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Author Correction: CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes. Genome Biol. 2024 Jul 08; 25(1):182. Unterman I, Avrahami D, Katsman E, Triche TJ, Glaser B, Berman BP. PMID: 38978142; PMCID: PMC11229263.
      View in: PubMed   Mentions:    Fields:    
    2. CelFiE-ISH: a probabilistic model for multi-cell type deconvolution from single-molecule DNA methylation haplotypes. Genome Biol. 2024 06 10; 25(1):151. Unterman I, Avrahami D, Katsman E, Triche TJ, Glaser B, Berman BP. PMID: 38858759; PMCID: PMC11163775.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    3. Structural variants involving MLLT10 fusion are associated with adverse outcomes in pediatric acute myeloid leukemia. Blood Adv. 2024 Apr 23; 8(8):2005-2017. Abla O, Ries RE, Triche T, Gerbing RB, Hirsch B, Raimondi S, Cooper T, Farrar JE, Buteyn N, Harmon LM, Wen H, Deshpande AJ, Kolb EA, Gamis AS, Aplenc R, Alonzo T, Meshinchi S. PMID: 38306602; PMCID: PMC11024924.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. BISCUIT: an efficient, standards-compliant tool suite for simultaneous genetic and epigenetic inference in bulk and single-cell studies. Nucleic Acids Res. 2024 Apr 12; 52(6):e32. Zhou W, Johnson BK, Morrison J, Beddows I, Eapen J, Katsman E, Semwal A, Habib WA, Heo L, Laird PW, Berman BP, Triche TJ, Shen H. PMID: 38412294; PMCID: PMC11014253.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    5. Validation of Myc-Associated Protein X (MAX) regulation in growth hormone secreting and nonfunctional pituitary adenoma. PLoS One. 2023; 18(4):e0284949. Tucker DW, Pangal DJ, Du R, Gogia AS, Tafreshi A, Ruzevick J, Hurth KT, Triche T, Micko A, Carpten JD, Shiroishi MS, Carmichael JD, Rhie SK, Zada G. PMID: 37104368; PMCID: PMC10138191.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. J Clin Oncol. 2023 06 01; 41(16):2949-2962. Farrar JE, Smith JL, Othus M, Huang BJ, Wang YC, Ries R, Hylkema T, Pogosova-Agadjanyan EL, Challa S, Leonti A, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb EA, Ma X, Stirewalt DL, Alonzo TA, Meshinchi S. PMID: 36795987; PMCID: PMC10414715.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    7. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nat Commun. 2022 09 19; 13(1):5487. Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing RB, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. PMID: 36123353; PMCID: PMC9485122.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    8. Non-Invasive Profiling of Advanced Prostate Cancer via Multi-Parametric Liquid Biopsy and Radiomic Analysis. Int J Mol Sci. 2022 Feb 25; 23(5). Morrison G, Buckley J, Ostrow D, Varghese B, Cen SY, Werbin J, Ericson N, Cunha A, Lu YT, George T, Smith J, Quinn D, Duddalwar V, Triche T, Goldkorn A. PMID: 35269713; PMCID: PMC8910093.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    9. Emerging variants of concern in SARS-CoV-2 membrane protein: a highly conserved target with potential pathological and therapeutic implications. Emerg Microbes Infect. 2021 Dec; 10(1):885-893. Shen L, Bard JD, Triche TJ, Judkins AR, Biegel JA, Gai X. PMID: 33896413; PMCID: PMC8118436.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    10. Rapidly emerging SARS-CoV-2 B.1.1.7 sub-lineage in the United States of America with spike protein D178H and membrane protein V70L mutations. Emerg Microbes Infect. 2021 Dec; 10(1):1293-1299. Shen L, Bard JD, Triche TJ, Judkins AR, Biegel JA, Gai X. PMID: 34125658; PMCID: PMC8238060.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    11. A B-cell developmental gene regulatory network is activated in infant AML. PLoS One. 2021; 16(11):e0259197. Bolouri H, Ries R, Pardo L, Hylkema T, Zhou W, Smith JL, Leonti A, Loken M, Farrar JE, Triche TJ, Meshinchi S. PMID: 34793513; PMCID: PMC8601427.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    12. Baseline Circulating Tumor Cell Count as a Prognostic Marker of PSA Response and Disease Progression in Metastatic Castrate-Sensitive Prostate Cancer (SWOG S1216). Clin Cancer Res. 2021 04 01; 27(7):1967-1973. Goldkorn A, Tangen C, Plets M, Morrison GJ, Cunha A, Xu T, Pinski JK, Ingles SA, Triche T, Harzstark AL, Kohli M, MacVicar GR, Vaena DA, Crispino AW, McConkey DJ, Lara PN, Hussain MHA, Quinn DI, Vogelzang NJ, Thompson IM, Agarwal N. PMID: 33500355; PMCID: PMC8026618.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCellsCTClinical Trials
    13. Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling. Epigenetics Chromatin. 2021 01 13; 14(1):7. Grit JL, Johnson BK, Dischinger PS, J Essenburg C, Adams M, Campbell S, Pollard K, Pratilas CA, Triche TJ, Graveel CR, Steensma MR. PMID: 33436083; PMCID: PMC7805211.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    14. Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor. EMBO Mol Med. 2021 02 05; 13(2):e12640. Chasse MH, Johnson BK, Boguslawski EA, Sorensen KM, Rosien JE, Kang MH, Reynolds CP, Heo L, Madaj ZB, Beddows I, Foxa GE, Kitchen-Goosen SM, Williams BO, Triche TJ, Grohar PJ. PMID: 33332735; PMCID: PMC7863405.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    15. Mathematical Oncology Comes to the Clinic: A Data-Driven Treatment for Financial Toxicity? Cancer Res. 2020 06 01; 80(11):2083-2084. Triche TJ. PMID: 32487587.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids. Cell Rep. 2019 12 17; 29(12):4069-4085.e6. George JW, Fan H, Johnson B, Carpenter TJ, Foy KK, Chatterjee A, Patterson AL, Koeman J, Adams M, Madaj ZB, Chesla D, Marsh EE, Triche TJ, Shen H, Teixeira JM. PMID: 31851934; PMCID: PMC6956710.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    17. Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study. Clin Cancer Res. 2020 02 01; 26(3):726-737. Smith JL, Ries RE, Hylkema T, Alonzo TA, Gerbing RB, Santaguida MT, Eidenschink Brodersen L, Pardo L, Cummings CL, Loeb KR, Le Q, Imren S, Leonti AR, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche TJ, Nguyen C, Meerzaman D, Loken MR, Oehler VG, Bolouri H, Meshinchi S. PMID: 31719049; PMCID: PMC7002196.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    18. Publisher Correction: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2019 Mar; 25(3):530. Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S. PMID: 30705421; PMCID: PMC7747938.
      View in: PubMed   Mentions: 5     Fields:    
    19. Landscape of Germline and Somatic Mitochondrial DNA Mutations in Pediatric Malignancies. Cancer Res. 2019 04 01; 79(7):1318-1330. Triska P, Kaneva K, Merkurjev D, Sohail N, Falk MJ, Triche TJ, Biegel JA, Gai X. PMID: 30709931; PMCID: PMC6445760.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    20. DNA methylation patterns of adult survivors of adolescent/young adult Hodgkin lymphoma compared to their unaffected monozygotic twin. Leuk Lymphoma. 2019 06; 60(6):1429-1437. Wang J, Van Den Berg D, Hwang AE, Weisenberger D, Triche T, Nathwani BN, Conti DV, Siegmund K, Mack TM, Horvath S, Cozen W. PMID: 30668190; PMCID: PMC7781082.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    21. Methylome of human senescent hematopoietic progenitors. Exp Hematol Oncol. 2018; 7:32. Capone S, Colombo AR, Johnson BK, Triche TJ, Ramsingh G. PMID: 30598855; PMCID: PMC6302458.
      View in: PubMed   Mentions: 3  
    22. Lack of APC somatic mutation is associated with early-onset colorectal cancer in African Americans. Carcinogenesis. 2018 12 13; 39(11):1331-1341. Xicola RM, Manojlovic Z, Augustus GJ, Kupfer SS, Emmadi R, Alagiozian-Angelova V, Triche T, Salhia B, Carpten J, Llor X, Ellis NA. PMID: 30239619; PMCID: PMC6292413.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    23. SeSAMe: reducing artifactual detection of DNA methylation by Infinium BeadChips in genomic deletions. Nucleic Acids Res. 2018 11 16; 46(20):e123. Zhou W, Triche TJ, Laird PW, Shen H. PMID: 30085201; PMCID: PMC6237738.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansCells
    24. Transposable Element Expression in Acute Myeloid Leukemia Transcriptome and Prognosis. Sci Rep. 2018 11 06; 8(1):16449. Colombo AR, Triche T, Ramsingh G. PMID: 30401833; PMCID: PMC6219593.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    25. OncoKids: A Comprehensive Next-Generation Sequencing Panel for Pediatric Malignancies. J Mol Diagn. 2018 11; 20(6):765-776. Hiemenz MC, Ostrow DG, Busse TM, Buckley J, Maglinte DT, Bootwalla M, Done J, Ji J, Raca G, Ryutov A, Xu X, Zhen CJ, Conroy JM, Hazard FK, Deignan JL, Rogers BB, Treece AL, Parham DM, Gai X, Judkins AR, Triche TJ, Biegel JA. PMID: 30138724.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    26. Erratum: The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2018 Apr 10; 24(4):526. Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S. PMID: 29634680.
      View in: PubMed   Mentions: 2     Fields:    
    27. Senescent human hematopoietic progenitors show elevated expression of transposable elements and inflammatory genes. Exp Hematol. 2018 06; 62:33-38.e6. Capone S, Connor KM, Colombo A, Li X, Triche TJ, Ramsingh G. PMID: 29549053.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    28. Author Correction: Suppression of Transposable Elements in Leukemic Stem Cells. Sci Rep. 2018 Mar 06; 8(1):4240. Colombo AR, Zubair A, Thiagarajan D, Nuzhdin S, Triche TJ, Ramsingh G. PMID: 29511219; PMCID: PMC5840359.
      View in: PubMed   Mentions:    Fields:    
    29. A phase 1 study of azacitidine combined with chemotherapy in childhood leukemia: a report from the TACL consortium. Blood. 2018 03 08; 131(10):1145-1148. Sun W, Triche T, Malvar J, Gaynon P, Sposto R, Yang X, Bittencourt H, Place AE, Messinger Y, Fraser C, Dalla-Pozza L, Salhia B, Jones P, Wayne AS, Gore L, Cooper TM, Liang G. PMID: 29339403; PMCID: PMC5863703.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    30. The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions. Nat Med. 2018 01; 24(1):103-112. Bolouri H, Farrar JE, Triche T, Ries RE, Lim EL, Alonzo TA, Ma Y, Moore R, Mungall AJ, Marra MA, Zhang J, Ma X, Liu Y, Liu Y, Auvil JMG, Davidsen TM, Gesuwan P, Hermida LC, Salhia B, Capone S, Ramsingh G, Zwaan CM, Noort S, Piccolo SR, Kolb EA, Gamis AS, Smith MA, Gerhard DS, Meshinchi S. PMID: 29227476; PMCID: PMC5907936.
      View in: PubMed   Mentions: 362     Fields:    Translation:HumansCells
    31. A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML. Clin Epigenetics. 2017; 9:108. Gore L, Triche TJ, Farrar JE, Wai D, Legendre C, Gooden GC, Liang WS, Carpten J, Lee D, Alvaro F, Macy ME, Arndt C, Barnette P, Cooper T, Martin L, Narendran A, Pollard J, Meshinchi S, Boklan J, Arceci RJ, Salhia B. PMID: 29034009; PMCID: PMC5629751.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCellsCTClinical Trials
    32. EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT. Blood Adv. 2017 Sep 12; 1(20):1635-1644. Merchant AA, Jorapur A, McManus A, Liu R, Krasnoperov V, Chaudhry P, Singh M, Harton L, Agajanian M, Kim M, Triche TJ, Druker BJ, Tyner JW, Gill PS. PMID: 29296810; PMCID: PMC5728330.
      View in: PubMed   Mentions: 10     Fields:    
    33. Suppression of Transposable Elements in Leukemic Stem Cells. Sci Rep. 2017 08 01; 7(1):7029. Colombo AR, Zubair A, Thiagarajan D, Nuzhdin S, Triche TJ, Ramsingh G. PMID: 28765607; PMCID: PMC5539300.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    34. Response: Making "perfect" the enemy of good. Blood. 2017 08 31; 130(9):1168-1169. Farrar JE, Neuberg D, Triche T, Bodine DM. PMID: 28754684; PMCID: PMC5580277.
      View in: PubMed   Mentions: 2     Fields:    
    35. GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML. Blood. 2017 06 29; 129(26):3465-3475. Chaudhry P, Singh M, Triche TJ, Guzman M, Merchant AA. PMID: 28487292; PMCID: PMC5492089.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    36. Preprocessing, normalization and integration of the Illumina HumanMethylationEPIC array with minfi. Bioinformatics. 2017 02 15; 33(4):558-560. Fortin JP, Triche TJ, Hansen KD. PMID: 28035024; PMCID: PMC5408810.
      View in: PubMed   Mentions: 408     Fields:    Translation:HumansCells
    37. A Rapid and Sensitive Next-Generation Sequencing Method to Detect RB1 Mutations Improves Care for Retinoblastoma Patients and Their Families. J Mol Diagn. 2016 07; 18(4):480-93. Li WL, Buckley J, Sanchez-Lara PA, Maglinte DT, Viduetsky L, Tatarinova TV, Aparicio JG, Kim JW, Au M, Ostrow D, Lee TC, O'Gorman M, Judkins A, Cobrinik D, Triche TJ. PMID: 27155049; PMCID: PMC5820122.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    38. Insulin-like Growth Factor 2 Gene Expression Molecularly Differentiates Pleuropulmonary Blastoma and Embryonal Rhabdomyosarcoma. J Pediatr Hematol Oncol. 2015 Aug; 37(6):e356-60. Venkatramani R, Triche TJ, Wang L, Shimada H, Mascarenhas L. PMID: 26056800; PMCID: PMC4506202.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med. 2015 Jun 25; 372(26):2481-98. Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fennell T, Fisher S, Gabriel S, Getz G, Gibbs R, Guin R, Hadjipanayis A, Hayes DN, Hinoue T, Hoadley K, Holt RA, Hoyle AP, Jefferys SR, Jones S, Jones CD, Kucherlapati R, Lai PH, Lander E, Lee S, Lichtenstein L, Ma Y, Maglinte DT, Mahadeshwar HS, Marra MA, Mayo M, Meng S, Meyerson ML, Mieczkowski PA, Moore RA, Mose LE, Mungall AJ, Pantazi A, Parfenov M, Park PJ, Parker JS, Perou CM, Protopopov A, Ren X, Roach J, Sabedot TS, Schein J, Schumacher SE, Seidman JG, Seth S, Shen H, Simons JV, Sipahimalani P, Soloway MG, Song X, Sun H, Tabak B, Tam A, Tan D, Tang J, Thiessen N, Triche T, Van Den Berg DJ, Veluvolu U, Waring S, Weisenberger DJ, Wilkerson MD, Wong T, Wu J, Xi L, Xu AW, Yang L, Zack TI, Zhang J, Aksoy BA, Arachchi H, Benz C, Bernard B, Carlin D, Cho J, DiCara D, Frazer S, Fuller GN, Gao J, Gehlenborg N, Haussler D, Heiman DI, Iype L, Jacobsen A, Ju Z, Katzman S, Kim H, Knijnenburg T, Kreisberg RB, Lawrence MS, Lee W, Leinonen K, Lin P, Ling S, Liu W, Liu Y, Liu Y, Lu Y, Mills G, Ng S, Noble MS, Paull E, Rao A, Reynolds S, Saksena G, Sanborn Z, Sander C, Schultz N, Senbabaoglu Y, Shen R, Shmulevich I, Sinha R, Stuart J, Sumer SO, Sun Y, Tasman N, Taylor BS, Voet D, Weinhold N, Weinstein JN, Yang D, Yoshihara K, Zheng S, Zhang W, Zou L, Abel T, Sadeghi S, Cohen ML, Eschbacher J, Hattab EM, Raghunathan A, Schniederjan MJ, Aziz D, Barnett G, Barrett W, Bigner DD, Boice L, Brewer C, Calatozzolo C, Campos B, Carlotti CG, Chan TA, Cuppini L, Curley E, Cuzzubbo S, Devine K, DiMeco F, Duell R, Elder JB, Fehrenbach A, Finocchiaro G, Friedman W, Fulop J, Gardner J, Hermes B, Herold-Mende C, Jungk C, Kendler A, Lehman NL, Lipp E, Liu O, Mandt R, McGraw M, Mclendon R, McPherson C, Neder L, Nguyen P, Noss A, Nunziata R, Ostrom QT, Palmer C, Perin A, Pollo B, Potapov A, Potapova O, Rathmell WK, Rotin D, Scarpace L, Schilero C, Senecal K, Shimmel K, Shurkhay V, Sifri S, Singh R, Sloan AE, Smolenski K, Staugaitis SM, Steele R, Thorne L, Tirapelli DP, Unterberg A, Vallurupalli M, Wang Y, Warnick R, Williams F, Wolinsky Y, Bell S, Rosenberg M, Stewart C, Huang F, Grimsby JL, Radenbaugh AJ, Zhang J. PMID: 26061751; PMCID: PMC4530011.
      View in: PubMed   Mentions: 1502     Fields:    Translation:HumansCells
    40. Discovery and validation of novel expression signature for postcystectomy recurrence in high-risk bladder cancer. J Natl Cancer Inst. 2014 Nov; 106(11). Mitra AP, Lam LL, Ghadessi M, Erho N, Vergara IA, Alshalalfa M, Buerki C, Haddad Z, Sierocinski T, Triche TJ, Skinner EC, Davicioni E, Daneshmand S, Black PC. PMID: 25344601; PMCID: PMC4241889.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    41. Reprogramming of the human intestinal epigenome by surgical tissue transposition. Genome Res. 2014 Apr; 24(4):545-53. Lay FD, Triche TJ, Tsai YC, Su SF, Martin SE, Daneshmand S, Skinner EC, Liang G, Chihara Y, Jones PA. PMID: 24515120; PMCID: PMC3975055.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    42. Characterization and drug resistance patterns of Ewing's sarcoma family tumor cell lines. PLoS One. 2013; 8(12):e80060. May WA, Grigoryan RS, Keshelava N, Cabral DJ, Christensen LL, Jenabi J, Ji L, Triche TJ, Lawlor ER, Reynolds CP. PMID: 24312454; PMCID: PMC3846563.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    43. T lymphocyte abnormalities in juvenile systemic sclerosis patients. Clin Immunol. 2013 Oct; 149(1):146-55. Reiff A, Weinberg KI, Triche T, Masinsin B, Mahadeo KM, Lin CH, Brown D, Parkman R. PMID: 23994768.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    44. A novel algorithm for simplification of complex gene classifiers in cancer. Cancer Res. 2013 Sep 15; 73(18):5625-32. Wilson RA, Teng L, Bachmeyer KM, Bissonnette ML, Husain AN, Parham DM, Triche TJ, Wing MR, Gastier-Foster JM, Barr FG, Hawkins DS, Anderson JR, Skapek SX, Volchenboum SL. PMID: 23913937; PMCID: PMC4233649.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    45. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med. 2013 05 30; 368(22):2059-74. Cancer Genome Atlas Research Network, Ley TJ, Miller C, Ding L, Raphael BJ, Mungall AJ, Robertson A, Hoadley K, Triche TJ, Laird PW, Baty JD, Fulton LL, Fulton R, Heath SE, Kalicki-Veizer J, Kandoth C, Klco JM, Koboldt DC, Kanchi KL, Kulkarni S, Lamprecht TL, Larson DE, Lin L, Lu C, McLellan MD, McMichael JF, Payton J, Schmidt H, Spencer DH, Tomasson MH, Wallis JW, Wartman LD, Watson MA, Welch J, Wendl MC, Ally A, Balasundaram M, Birol I, Butterfield Y, Chiu R, Chu A, Chuah E, Chun HJ, Corbett R, Dhalla N, Guin R, He A, Hirst C, Hirst M, Holt RA, Jones S, Karsan A, Lee D, Li HI, Marra MA, Mayo M, Moore RA, Mungall K, Parker J, Pleasance E, Plettner P, Schein J, Stoll D, Swanson L, Tam A, Thiessen N, Varhol R, Wye N, Zhao Y, Gabriel S, Getz G, Sougnez C, Zou L, Leiserson MD, Vandin F, Wu HT, Applebaum F, Baylin SB, Akbani R, Broom BM, Chen K, Motter TC, Nguyen K, Weinstein JN, Zhang N, Ferguson ML, Adams C, Black A, Bowen J, Gastier-Foster J, Grossman T, Lichtenberg T, Wise L, Davidsen T, Demchok JA, Shaw KR, Sheth M, Sofia HJ, Yang L, Downing JR, Eley G. PMID: 23634996; PMCID: PMC3767041.
      View in: PubMed   Mentions: 2483     Fields:    Translation:HumansCells
    46. Low-level processing of Illumina Infinium DNA Methylation BeadArrays. Nucleic Acids Res. 2013 Apr; 41(7):e90. Triche TJ, Weisenberger DJ, Van Den Berg D, Laird PW, Siegmund KD. PMID: 23476028; PMCID: PMC3627582.
      View in: PubMed   Mentions: 465     Fields:    Translation:HumansCells
    47. FOXM1 is an oncogenic mediator in Ewing Sarcoma. PLoS One. 2013; 8(1):e54556. Christensen L, Joo J, Lee S, Wai D, Triche TJ, May WA. PMID: 23365673; PMCID: PMC3554707.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    48. An epigenomic mechanism in retinoblastoma: the end of the story? Genome Med. 2012 Feb 24; 4(2):15. Murphree AL, Triche TJ. PMID: 22364211; PMCID: PMC3392761.
      View in: PubMed   Mentions: 2     Fields:    
    49. Influence of RNA labeling on expression profiling of microRNAs. J Mol Diagn. 2012 Jan; 14(1):12-21. Kaddis JS, Wai DH, Bowers J, Hartmann N, Baeriswyl L, Bajaj S, Anderson MJ, Getts RC, Triche TJ. PMID: 22074760; PMCID: PMC3338349.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    50. Quantitative expression profiling in formalin-fixed paraffin-embedded samples by affymetrix microarrays. J Mol Diagn. 2010 Jul; 12(4):409-17. Abdueva D, Wing M, Schaub B, Triche T, Davicioni E. PMID: 20522636; PMCID: PMC2893624.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    51. Prediction of human functional genetic networks from heterogeneous data using RVM-based ensemble learning. Bioinformatics. 2010 Mar 15; 26(6):807-13. Wu CC, Asgharzadeh S, Triche TJ, D'Argenio DZ. PMID: 20134029; PMCID: PMC2832827.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    52. Gene expression profiling for survival prediction in pediatric rhabdomyosarcomas: a report from the children's oncology group. J Clin Oncol. 2010 Mar 01; 28(7):1240-6. Davicioni E, Anderson JR, Buckley JD, Meyer WH, Triche TJ. PMID: 20124188; PMCID: PMC3040045.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    53. Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation. FASEB J. 2010 Mar; 24(3):833-43. Wang A, Alimova IN, Luo P, Jong A, Triche TJ, Wu L. PMID: 19917671; PMCID: PMC2830139.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    54. Molecular classification of rhabdomyosarcoma--genotypic and phenotypic determinants of diagnosis: a report from the Children's Oncology Group. Am J Pathol. 2009 Feb; 174(2):550-64. Davicioni E, Anderson MJ, Finckenstein FG, Lynch JC, Qualman SJ, Shimada H, Schofield DE, Buckley JD, Meyer WH, Sorensen PH, Triche TJ. PMID: 19147825; PMCID: PMC2630563.
      View in: PubMed   Mentions: 121     Fields:    Translation:Humans
    55. Sparse representation and Bayesian detection of genome copy number alterations from microarray data. Bioinformatics. 2008 Feb 01; 24(3):309-18. Pique-Regi R, Monso-Varona J, Ortega A, Seeger RC, Triche TJ, Asgharzadeh S. PMID: 18203770; PMCID: PMC2704547.
      View in: PubMed   Mentions: 61     Fields:    Translation:Humans
    56. Hierarchical Bayes prioritization of marker associations from a genome-wide association scan for further investigation. Genet Epidemiol. 2007 Dec; 31(8):871-82. Lewinger JP, Conti DV, Baurley JW, Triche TJ, Thomas DC. PMID: 17654612.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    57. Experimental comparison and evaluation of the Affymetrix exon and U133Plus2 GeneChip arrays. PLoS One. 2007 Sep 19; 2(9):e913. Abdueva D, Wing MR, Schaub B, Triche TJ. PMID: 17878948; PMCID: PMC1976394.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    58. Histone deacetylase 1 gene expression and sensitization of multidrug-resistant neuroblastoma cell lines to cytotoxic agents by depsipeptide. J Natl Cancer Inst. 2007 Jul 18; 99(14):1107-19. Keshelava N, Davicioni E, Wan Z, Ji L, Sposto R, Triche TJ, Reynolds CP. PMID: 17623797.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    59. E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase. Cancer Res. 2007 Apr 01; 67(7):3094-105. Kang HG, Jenabi JM, Zhang J, Keshelava N, Shimada H, May WA, Ng T, Reynolds CP, Triche TJ, Sorensen PH. PMID: 17409416; PMCID: PMC3906735.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansCells
    60. Population-based study of early age-related macular degeneration: role of the complement factor H Y402H polymorphism in bilateral but not unilateral disease. Ophthalmology. 2007 Jan; 114(1):99-103. Tedeschi-Blok N, Buckley J, Varma R, Triche TJ, Hinton DR. PMID: 17198853.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    61. Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar rhabdomyosarcomas. Cancer Res. 2006 Jul 15; 66(14):6936-46. Davicioni E, Finckenstein FG, Shahbazian V, Buckley JD, Triche TJ, Anderson MJ. PMID: 16849537.
      View in: PubMed   Mentions: 149     Fields:    Translation:HumansCells
    62. EWS-FLI1 fusion protein up-regulates critical genes in neural crest development and is responsible for the observed phenotype of Ewing's family of tumors. Cancer Res. 2005 Jun 01; 65(11):4633-44. Hu-Lieskovan S, Zhang J, Wu L, Shimada H, Schofield DE, Triche TJ. PMID: 15930281.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansAnimalsCells
    63. Retinoid-modulated MAT1 ubiquitination and CAK activity. FASEB J. 2004 Nov; 18(14):1734-6. He Q, Peng H, Collins SJ, Triche TJ, Wu L. PMID: 15345685.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    64. Selective usage of D-Type cyclins by Ewing's tumors and rhabdomyosarcomas. Cancer Res. 2004 Sep 01; 64(17):6026-34. Zhang J, Hu S, Schofield DE, Sorensen PH, Triche TJ. PMID: 15342383.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    65. MAT1-modulated cyclin-dependent kinase-activating kinase activity cross-regulates neuroblastoma cell G1 arrest and neurite outgrowth. Cancer Res. 2004 May 01; 64(9):2977-83. Zhang S, He Q, Peng H, Tedeschi-Blok N, Triche TJ, Wu L. PMID: 15126328.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    66. Infectomics: genomics and proteomics of microbial infections. Funct Integr Genomics. 2002 Apr; 1(6):331-44. Huang SH, Triche T, Jong AY. PMID: 11957108.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    67. Presence of well-differentiated rhabdomyoblasts at the end of therapy for pelvic rhabdomyosarcoma: implications for the outcome. J Pediatr Hematol Oncol. 2000 Mar-Apr; 22(2):106-11. Ortega JA, Rowland J, Monforte H, Malogolowkin M, Triche T. PMID: 10779022.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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