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John David Carmichael, MD

Title(s)Associate Professor of Clinical Medicine
Phone+1 323 442 6179
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    Other Positions
    Title(s)Co-Director, Pituitary Program at Keck Medical Center


    Collapse Biography 
    Collapse Awards and Honors
    NIH Clinical Research Feasibility Funds (CReFF)2008  - 2009Growth Hormone Feedback in Patients with Acromegaly, Type 2 Diabetes Mellitus, and Healthy Adults
    NIH Loan Repayment Program2009  - 2013Growth Hormone Feedback in Patients with Acromegaly, Type 2 Diabetes Mellitus, and Healthy Adults

    Collapse Overview 
    Collapse Overview
    John D. Carmichael, MD, is an associate professor of clinical medicine in the Department of Medicine’s division of endocrinology, diabetes and metabolism at Keck School of Medicine of USC.

    Dr. Carmichael is board certified in internal medicine and diabetes, endocrinology and metabolism. His clinical and research interests include the diagnosis and treatment of pituitary disease. He has received NIH funding for his research in growth hormone feedback mechanisms in patients with acromegaly and type 2 diabetes mellitus.

    He has written articles for The Journal of? Clinical Endocrinology and Metabolism, Clinical Endocrinology, Pituitary, Endocrine, and Current Opinion in Endocrinology and Diabetes. He sits on the editorial board for Pituitary and is a senior editorial board member for Endocrinology, Diabetes & Metabolism Case Reports. He is a member of the Endocrine Society, the Pituitary Society, and the American Association of Clinical Endocrinologists where he serves on the Pituitary Scientific Committee.

    After finishing his clinical training at NYU in 2004, Dr. Carmichael worked as a clinical researcher at NYU focusing on clinical trials in pituitary disease. He received a grant from Genetech to support his work during this time. In 2006, he went on to work at Cedars-Sinai Medical Center in their pituitary center. His work included care of patients with pituitary disease and clinical research in the diagnosis and treatment of patients with pituitary tumors. He held an appointment in the department of medicine at UCLA, devoting his time to the education of medical students, residents and fellows in multiple topics related to pituitary disorders. In 2014, Dr. Carmichael joined the faculty at the Keck School of Medicine of USC.

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Memel Z, Chesney K, Pangal DJ, Bonney PA, Carmichael JD, Zada G. Outcomes Following Transsphenoidal Pituitary Surgery in the Elderly: A Retrospective Single-Center Review. Oper Neurosurg (Hagerstown). 2019 Mar 01; 16(3):302-309. PMID: 29800459.
      View in: PubMed
    2. Jackanich A, Tavakol S, Strickland BA, Rutkowski M, Kamel D, Carmichael JD, Weiss M, Zada G. Clinical utility of routine postoperative morning cortisol monitoring in detecting new hypothalamic-pituitary-adrenal axis insufficiency following endoscopic transsphenoidal surgery for sellar lesions. J Neurosurg. 2019 Mar 01; 1-5. PMID: 30835697.
      View in: PubMed
    3. Bakhsheshian J, Wheeler S, Strickland BA, Pham MH, Rennert RC, Carmichael J, Weiss M, Zada G. Surgical Outcomes Following Repeat Transsphenoidal Surgery for Nonfunctional Pituitary Adenomas: A Retrospective Comparative Study. Oper Neurosurg (Hagerstown). 2019 Feb 01; 16(2):127-135. PMID: 29767762.
      View in: PubMed
    4. Chesney K, Memel Z, Pangal DJ, Donoho D, Hurth K, Mathew A, Carmichael JD, Zada G. Variability and Lack of Prognostic Value Associated With Atypical Pituitary Adenoma Diagnosis: A Systematic Review and Critical Assessment of the Diagnostic Criteria. Neurosurgery. 2018 Oct 01; 83(4):602-610. PMID: 29165661.
      View in: PubMed
    5. Wedemeyer MA, Lin M, Fredrickson VL, Arakelyan A, Bradley D, Donoho DA, Hurth KM, Weiss MH, Carmichael JD, Zada G. Recurrent Rathke's Cleft Cysts: Incidence and Surgical Management in a Tertiary Pituitary Center over 2 Decades. Oper Neurosurg (Hagerstown). 2018 Sep 22. PMID: 30247673.
      View in: PubMed
    6. Seltzer J, Wedemeyer MA, Bonney PA, Carmichael JD, Weiss M, Zada G. Outcomes following transsphenoidal surgical management of incidental pituitary adenomas: a series of 52 patients over a 17-year period. J Neurosurg. 2018 Jun 01; 1-9. PMID: 29999467.
      View in: PubMed
    7. Lin M, Wedemeyer MA, Bradley D, Donoho DA, Fredrickson VL, Weiss MH, Carmichael JD, Zada G. Long-term surgical outcomes following transsphenoidal surgery in patients with Rathke's cleft cysts. J Neurosurg. 2018 May 18; 1-7. PMID: 29775155.
      View in: PubMed
    8. Agam MS, Wedemeyer MA, Wrobel B, Weiss MH, Carmichael JD, Zada G. Complications associated with microscopic and endoscopic transsphenoidal pituitary surgery: experience of 1153 consecutive cases treated at a single tertiary care pituitary center. J Neurosurg. 2018 May 01; 1-8. PMID: 29999459.
      View in: PubMed
    9. Law M, Wang R, Liu CJ, Shiroishi MS, Carmichael JD, Mack WJ, Weiss M, Wang DJJ, Toga AW, Zada G. Value of pituitary gland MRI at 7 T in Cushing's disease and relationship to inferior petrosal sinus sampling: case report. J Neurosurg. 2018 Mar 01; 1-5. PMID: 29570013.
      View in: PubMed
    10. Bonert V, Carmichael J, Wu Z, Mirocha J, Perez DA, Clarke NJ, Reitz RE, McPhaul MJ, Mamelak A. Discordance between mass spectrometry and immunometric IGF-1 assay in pituitary disease: a prospective study. Pituitary. 2018 Feb; 21(1):65-75. PMID: 29218459.
      View in: PubMed
    11. Rolston VS, Boroujerdi L, Long MD, McGovern DPB, Chen W, Martin CF, Sandler RS, Carmichael JD, Dubinsky M, Melmed GY. The Influence of Hormonal Fluctuation on Inflammatory Bowel Disease Symptom Severity-A Cross-Sectional Cohort Study. Inflamm Bowel Dis. 2018 01 18; 24(2):387-393. PMID: 29361085.
      View in: PubMed
    12. Fahlbusch R, Kleinberg D, Biller B, Bonert V, Buchfelder M, Cappabianca P, Carmichael J, Chandler W, Colao A, George A, Klibanski A, Knopp E, Kreutzer J, Kundurti N, Lesser M, Mamelak A, Pivonello R, Post K, Swearingen B, Vance ML, Barkan A. Surgical debulking of pituitary adenomas improves responsiveness to octreotide lar in the treatment of acromegaly. Pituitary. 2017 Dec; 20(6):668-675. PMID: 28825168.
      View in: PubMed
    13. Strickland BA, Pham M, Bakhsheshian J, Carmichael J, Weiss M, Zada G. Endoscopic Endonasal Transsphenoidal Drainage of a Spontaneous Candida glabrata Pituitary Abscess. World Neurosurg. 2018 Jan; 109:467-470. PMID: 29079259.
      View in: PubMed
    14. Strickland BA, Lucas J, Harris B, Kulubya E, Bakhsheshian J, Liu C, Wrobel B, Carmichael JD, Weiss M, Zada G. Identification and repair of intraoperative cerebrospinal fluid leaks in endonasal transsphenoidal pituitary surgery: surgical experience in a series of 1002 patients. J Neurosurg. 2018 Aug; 129(2):425-429. PMID: 28960156.
      View in: PubMed
    15. Carmichael JD, Broder MS, Cherepanov D, Chang E, Mamelak A, Said Q, Neary MP, Bonert V. Long-term treatment outcomes of acromegaly patients presenting biochemically-uncontrolled at a tertiary pituitary center. BMC Endocr Disord. 2017 Aug 04; 17(1):49. PMID: 28778166.
      View in: PubMed
    16. Babu H, Ortega A, Nuno M, Dehghan A, Schweitzer A, Bonert HV, Carmichael JD, Cooper O, Melmed S, Mamelak AN. Long-Term Endocrine Outcomes Following Endoscopic Endonasal Transsphenoidal Surgery for Acromegaly and Associated Prognostic Factors. Neurosurgery. 2017 Aug 01; 81(2):357-366. PMID: 28368500.
      View in: PubMed
    17. Geer EB, Ayala A, Bonert V, Carmichael JD, Gordon MB, Katznelson L, Manuylova E, Shafiq I, Surampudi V, Swerdloff RS, Broder MS, Cherepanov D, Eagan M, Lee J, Said Q, Neary MP, Biller BMK. Follow-up intervals in patients with Cushing's disease: recommendations from a panel of experienced pituitary clinicians. Pituitary. 2017 Aug; 20(4):422-429. PMID: 28275992.
      View in: PubMed
    18. Geer EB, Shafiq I, Gordon MB, Bonert V, Ayala A, Swerdloff RS, Katznelson L, Lalazar Y, Manuylova E, Pulaski-Liebert KJ, Carmichael JD, Hannoush Z, Surampudi V, Broder MS, Cherepanov D, Eagan M, Lee J, Said Q, Neary MP, Biller BMK. BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. Endocr Pract. 2017 Aug; 23(8):962-970. PMID: 28614003.
      View in: PubMed
    19. Carmichael JD, Broder MS, Cherepanov D, Chang E, Mamelak A, Said Q, Neary MP, Bonert V. The association between biochemical control and cardiovascular risk factors in acromegaly. BMC Endocr Disord. 2017 Mar 09; 17(1):15. PMID: 28279153.
      View in: PubMed
    20. Donoho DA, Bose N, Zada G, Carmichael JD. Management of aggressive growth hormone secreting pituitary adenomas. Pituitary. 2017 Feb; 20(1):169-178. PMID: 27987061.
      View in: PubMed
    21. Seltzer J, Carmichael JD, Commins D, Liu CS, Omura E, Chang E, Zada G. Prolactin-Secreting Pituitary Carcinoma with Dural Metastasis: Diagnosis, Treatment, and Future Directions. World Neurosurg. 2016 Jul; 91:676.e23-8. PMID: 27157283.
      View in: PubMed
    22. Seltzer J, Scotton TC, Kang K, Zada G, Carmichael JD. Gene expression in prolactinomas: a systematic review. Pituitary. 2016 Feb; 19(1):93-104. PMID: 26238304.
      View in: PubMed
    23. Broder MS, Chang E, Ludlam WH, Neary MP, Carmichael JD. Patterns of pharmacologic treatment in US patients with acromegaly. Curr Med Res Opin. 2016 05; 32(5):799-805. PMID: 26609770.
      View in: PubMed
    24. Jeswani S, Nuño M, Wu A, Bonert V, Carmichael JD, Black KL, Chu R, King W, Mamelak AN. Comparative analysis of outcomes following craniotomy and expanded endoscopic endonasal transsphenoidal resection of craniopharyngioma and related tumors: a single-institution study. J Neurosurg. 2016 Mar; 124(3):627-38. PMID: 26361276.
      View in: PubMed
    25. Woodmansee WW, Carmichael J, Kelly D, Katznelson L. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY DISEASE STATE CLINICAL REVIEW: POSTOPERATIVE MANAGEMENT FOLLOWING PITUITARY SURGERY. Endocr Pract. 2015 Jul; 21(7):832-8. PMID: 26172128.
      View in: PubMed
    26. Newman CB, Carmichael JD, Kleinberg DL. Effects of low dose versus high dose human growth hormone on body composition and lipids in adults with GH deficiency: a meta-analysis of placebo-controlled randomized trials. Pituitary. 2015 Jun; 18(3):297-305. PMID: 24810900.
      View in: PubMed
    27. Seltzer J, Lucas J, Commins D, Lerner O, Lerner A, Carmichael JD, Zada G. Ectopic ACTH-secreting pituitary adenoma of the sphenoid sinus: case report of endoscopic endonasal resection and systematic review of the literature. Neurosurg Focus. 2015 Feb; 38(2):E10. PMID: 25639312.
      View in: PubMed
    28. Wilson D, Jin DL, Wen T, Carmichael JD, Cen S, Mack WJ, Zada G. Demographic factors, outcomes, and patient access to transsphenoidal surgery for Cushing's disease: analysis of the Nationwide Inpatient Sample from 2002 to 2010. Neurosurg Focus. 2015 Feb; 38(2):E2. PMID: 25639320.
      View in: PubMed
    29. Carmichael JD, Zada G, Selman WR. Making the diagnosis of cyclic Cushing's syndrome: a position statement from the topic editors. Neurosurg Focus. 2015 Feb; 38(2):E8. PMID: 25639326.
      View in: PubMed
    30. Zada G, Carmichael JD, Selman WR. Introduction: Cushing's disease: a century of evolving diagnostics and therapeutics for an often elusive entity. Neurosurg Focus. 2015 Feb; 38(2):E1. PMID: 25639311.
      View in: PubMed
    31. Bonert V, Bose N, Carmichael JD. Cyclic Cushing's disease with misleading inferior petrosal sinus sampling results during a trough phase. Neurosurg Focus. 2015 Feb; 38(2):E7. PMID: 25639325.
      View in: PubMed
    32. Seltzer J, Ashton CE, Scotton TC, Pangal D, Carmichael JD, Zada G. Gene and protein expression in pituitary corticotroph adenomas: a systematic review of the literature. Neurosurg Focus. 2015 Feb; 38(2):E17. PMID: 25639319.
      View in: PubMed
    33. Cuevas-Ramos D, Carmichael JD, Cooper O, Bonert VS, Gertych A, Mamelak AN, Melmed S. A structural and functional acromegaly classification. J Clin Endocrinol Metab. 2015 Jan; 100(1):122-31. PMID: 25250634; PMCID: PMC4283008.
    34. Schievink WI, Nuño M, Rozen TD, Maya MM, Mamelak AN, Carmichael J, Bonert VS. Hyperprolactinemia due to spontaneous intracranial hypotension. J Neurosurg. 2015 May; 122(5):1020-5. PMID: 25380110.
      View in: PubMed
    35. Dow A, Russell RV, Bonert V, Carmichael J, Mamelak A, Pressman BD, Fan X, Yu R. A protracted and aggressive variant of lymphocytic hypophysitis with mammillary body involvement and cognitive dysfunction. Endocr Pract. 2014 Nov; 20(11):e225-9. PMID: 25100390.
      View in: PubMed
    36. Feng M, Carmichael JD, Bonert V, Bannykh S, Mamelak AN. Surgical management of pituicytomas: case series and comprehensive literature review. Pituitary. 2014 Oct; 17(5):399-413. PMID: 24037647.
      View in: PubMed
    37. Carmichael JD, Bonert VS, Nuño M, Ly D, Melmed S. Acromegaly clinical trial methodology impact on reported biochemical efficacy rates of somatostatin receptor ligand treatments: a meta-analysis. J Clin Endocrinol Metab. 2014 May; 99(5):1825-33. PMID: 24606084; PMCID: PMC4010703.
    38. Cooper O, Mamelak A, Bannykh S, Carmichael J, Bonert V, Lim S, Cook-Wiens G, Ben-Shlomo A. Prolactinoma ErbB receptor expression and targeted therapy for aggressive tumors. Endocrine. 2014 Jun; 46(2):318-27. PMID: 24287797.
      View in: PubMed
    39. Dow A, Yu R, Carmichael J. Too little or too much corticosteroid? Coexisting adrenal insufficiency and Cushing's syndrome from chronic, intermittent use of intranasal betamethasone. Endocrinol Diabetes Metab Case Rep. 2013; 2013:130036. PMID: 24616769.
      View in: PubMed
    40. Mamelak AN, Carmichael J, Bonert VH, Cooper O, Melmed S. Single-surgeon fully endoscopic endonasal transsphenoidal surgery: outcomes in three-hundred consecutive cases. Pituitary. 2013 Sep; 16(3):393-401. PMID: 23011322.
      View in: PubMed
    41. Carmichael JD, Fleseriu M. Mifepristone: is there a place in the treatment of Cushing's disease? Endocrine. 2013 Aug; 44(1):20-32. PMID: 23192246.
      View in: PubMed
    42. Carmichael JD. Update on the diagnosis and management of hypophysitis. Curr Opin Endocrinol Diabetes Obes. 2012 Aug; 19(4):314-21. PMID: 22543347.
      View in: PubMed
    43. Carmichael JD. Lanreotide depot deep subcutaneous injection: a new method of delivery and its associated benefits. Patient Prefer Adherence. 2012; 6:73-82. PMID: 22298946.
      View in: PubMed
    44. Mamelak AN, Carmichael JD, Park P, Bannykh S, Fan X, Bonert HV. Atypical pituitary adenoma with malignant features. Pituitary. 2011 Mar; 14(1):92-7. PMID: 18949563.
      View in: PubMed
    45. Carmichael JD, Bonert VS, Mirocha JM, Melmed S. The utility of oral glucose tolerance testing for diagnosis and assessment of treatment outcomes in 166 patients with acromegaly. J Clin Endocrinol Metab. 2009 Feb; 94(2):523-7. PMID: 19033371.
      View in: PubMed
    46. Bonert VS, Kennedy L, Petersenn S, Barkan A, Carmichael J, Melmed S. Lipodystrophy in patients with acromegaly receiving pegvisomant. J Clin Endocrinol Metab. 2008 Sep; 93(9):3515-8. PMID: 18611977.
      View in: PubMed
    47. Carmichael JD, Bonert VS. Medical therapy: options and uses. Rev Endocr Metab Disord. 2008 Mar; 9(1):71-81. PMID: 18163211.
      View in: PubMed
    48. Carmichael JD, Danoff A, Milani D, Roubenoff R, Lesser ML, Livote E, Reitz RE, Ferris S, Kleinberg DL. GH peak response to GHRH-arginine: relationship to insulin resistance and other cardiovascular risk factors in a population of adults aged 50-90. Clin Endocrinol (Oxf). 2006 Aug; 65(2):169-77. PMID: 16886956; PMCID: PMC1618818.
    49. Milani D, Carmichael JD, Welkowitz J, Ferris S, Reitz RE, Danoff A, Kleinberg DL. Variability and reliability of single serum IGF-I measurements: impact on determining predictability of risk ratios in disease development. J Clin Endocrinol Metab. 2004 May; 89(5):2271-4. PMID: 15126552; PMCID: PMC3251209.