Kyle M. Hurth, MD, PhD

Title(s)Associate Professor of Clinical Pathology, Medical Director, Immunohistochemistry Laboratory
SchoolKeck School of Medicine of Usc
AddressHC4 1450 San Pablo Street
Health Sciences Campus
Los Angeles CA 90089-9092
Phone+1 323 442 8592
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Recurring homozygous ACTN2 variant (p.Arg506Gly) causes a recessive myopathy. Ann Clin Transl Neurol. 2024 Mar; 11(3):629-640. Donkervoort S, Mohassel P, O'Leary M, Bonner DE, Hartley T, Acquaye N, Brull A, Mozaffar T, Saporta MA, Dyment DA, Sampson JB, Pajusalu S, Austin-Tse C, Hurth K, Cohen JS, McWalter K, Warman-Chardon J, Crunk A, Foley AR, Undiagnosed Diseases Network, Mammen AL, Wheeler MT, O'Donnell-Luria A, Bönnemann CG. PMID: 38311799; PMCID: PMC10963296.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Clinical Implications of Pituitary Adenomas Exhibiting Dual Transcription Factor Staining: A Case Series of 27 Patients. World Neurosurg. 2024 Feb; 182:e62-e66. Bove I, Cheok SK, Feng JJ, Briggs RG, Ruzevick J, Cote DJ, Shah I, Little A, Laws E, Castro AV, Carmichael J, Shiroishi M, Hurth K, Zada G. PMID: 37967742.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. ATM-Inhibitor AZD1390 Is a Radiosensitizer for Breast Cancer CNS Metastasis. Clin Cancer Res. 2023 11 01; 29(21):4492-4503. Tew BY, Kalfa AJ, Yang Z, Hurth KM, Simon T, Abnoosian E, Durant ST, Hamerlik P, Salhia B. PMID: 37585496; PMCID: PMC10618650.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. A repository of grade 1 and 2 meningioma MRIs in a public dataset for radiomics reproducibility tests. Med Phys. 2024 Mar; 51(3):2334-2344. Vassantachart A, Cao Y, Shen Z, Cheng K, Gribble M, Ye JC, Zada G, Hurth K, Mathew A, Guzman S, Yang W. PMID: 37815256; PMCID: PMC10939960.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Breast-to-brain metastasis is exacerbated with chemotherapy through blood-cerebrospinal fluid barrier and induces Alzheimer's-like pathology. J Neurosci Res. 2023 12; 101(12):1900-1913. Saatian B, Deshpande K, Herrera R, Sedighi S, Eisenbarth R, Iyer M, Das D, Julian A, Martirosian V, Lowman A, LaViolette P, Remsik J, Boire A, Sankey E, Fecci PE, Shiroishi MS, Chow F, Hurth K, Neman J. PMID: 37787045; PMCID: PMC10769085.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Neurotropism of SARS-CoV-2: A Pathological Examination of Neurosurgical Specimens. Neurosurgery. 2024 02 01; 94(2):379-388. Fujii T, Rennert RC, Hurth KM, Ward PM, Campan M, Mathew AJ, Dubeau L, Wallace WD, Liu CY, Russin JJ. PMID: 37728367.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Prevalence of Frontotemporal Dementia in Females of 5 Hispanic Families With R159H VCP Multisystem Proteinopathy. Neurol Genet. 2023 Feb; 9(1):e200037. Shmara A, Gibbs L, Mahoney RP, Hurth K, Goodwill VS, Cuber A, Im R, Pizzo DP, Brown J, Laukaitis C, Mahajan S, Kimonis V. PMID: 36644447; PMCID: PMC9833818.
      View in: PubMed   Mentions: 3  
    8. Highly Multiplexed Spatially Resolved Proteomic and Transcriptional Profiling of the Glioblastoma Microenvironment Using Archived Formalin-Fixed Paraffin-Embedded Specimens. Mod Pathol. 2023 01; 36(1):100034. Kim Y, Danaher P, Cimino PJ, Hurth K, Warren S, Glod J, Beechem JM, Zada G, McEachron TA. PMID: 36788070; PMCID: PMC9937641.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. Detection of perillyl alcohol and its metabolite perillic acid in postsurgical glioblastoma tissue after intranasal administration of NEO100: illustrative case. J Neurosurg Case Lessons. 2022 Aug 22; 4(8). Schönthal AH, Swenson S, Bonney PA, Wagle N, Simmon VF, Mathew AJ, Hurth KM, Chen TC. PMID: 36088606; PMCID: PMC9706323.
      View in: PubMed   Mentions: 3  
    10. Automatic differentiation of Grade I and II meningiomas on magnetic resonance image using an asymmetric convolutional neural network. Sci Rep. 2022 03 09; 12(1):3806. Vassantachart A, Cao Y, Gribble M, Guzman S, Ye JC, Hurth K, Mathew A, Zada G, Fan Z, Chang EL, Yang W. PMID: 35264655; PMCID: PMC8907289.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    11. Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease. Neurobiol Aging. 2022 04; 112:39-54. Dahl MJ, Mather M, Werkle-Bergner M, Kennedy BL, Guzman S, Hurth K, Miller CA, Qiao Y, Shi Y, Chui HC, Ringman JM. PMID: 35045380; PMCID: PMC8976827.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    12. Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination. Cell Rep. 2021 Jul 27; 36(4):109475. Martirosian V, Deshpande K, Zhou H, Shen K, Smith K, Northcott P, Lin M, Stepanosyan V, Das D, Remsik J, Isakov D, Boire A, De Feyter H, Hurth K, Li S, Wiemels J, Wiemels J, Nakamura B, Shao L, Danilov C, Chen T, Neman J. PMID: 34320362.
      View in: PubMed   Mentions: 2     Fields:    
    13. Monoclonal Antibody Therapy against Acinetobacter baumannii. Infect Immun. 2021 09 16; 89(10):e0016221. Nielsen TB, Yan J, Slarve M, Lu P, Li R, Ruiz J, Lee B, Burk E, Talyansky Y, Oelschlaeger P, Hurth K, Win W, Luna BM, Bonomo RA, Spellberg B. PMID: 34310884; PMCID: PMC8445169.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    14. Reducing body myopathy associated with the LIM2 p.(His123Arg) FHL1 variant. Clin Neurol Neurosurg. 2021 08; 207:106795. Darki L, Jalali-Sohi A, Guzman S, Mathew AJ, Bucelli RC, Hurth KM, Beydoun SR. PMID: 34273663.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination. Cell Rep. 2021 06 29; 35(13):109302. Martirosian V, Deshpande K, Zhou H, Shen K, Smith K, Northcott P, Lin M, Stepanosyan V, Das D, Remsik J, Isakov D, Boire A, De Feyter H, Hurth K, Li S, Wiemels J, Wiemels J, Nakamura B, Shao L, Danilov C, Chen T, Neman J. PMID: 34192534; PMCID: PMC8848833.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    16. Silent corticotroph pituitary adenomas: clinical characteristics, long-term outcomes, and management of disease recurrence. J Neurosurg. 2021 May 07; 135(6):1706-1713. Strickland BA, Shahrestani S, Briggs RG, Jackanich A, Tavakol S, Hurth K, Shiroishi MS, Liu CJ, Carmichael JD, Weiss M, Zada G. PMID: 33962375.
      View in: PubMed   Mentions: 6     Fields:    
    17. Comparative study of neuroendocrine acquisition and biomarker expression between neuroendocrine and usual prostatic carcinoma. Prostate. 2021 06; 81(8):469-477. Xiao GQ, Ho G, Suen C, Hurth KM. PMID: 33848377.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Clinical utility of comprehensive genomic profiling in central nervous system tumors of children and young adults. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab037. Ji J, Kaneva K, Hiemenz MC, Dhall G, Davidson TB, Erdreich-Epstein A, Hawes D, Hurth K, Margol AS, Mathew AJ, Robison NJ, Schmidt RJ, Tran HN, Judkins AR, Cotter JA, Biegel JA. PMID: 33948563; PMCID: PMC8080244.
      View in: PubMed   Mentions: 4  
    19. Phase I trial of intranasal NEO100, highly purified perillyl alcohol, in adult patients with recurrent glioblastoma. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab005. Schönthal AH, Peereboom DM, Wagle N, Lai R, Mathew AJ, Hurth KM, Simmon VF, Howard SP, Taylor LP, Chow F, da Fonseca CO, Chen TC. PMID: 33604574; PMCID: PMC7879254.
      View in: PubMed   Mentions: 8  
    20. Chronic Aspiration Pneumonitis Caused by Spontaneous Cerebrospinal Fluid Fistulae of the Skull Base. Laryngoscope. 2021 03; 131(3):462-466. Or M, Buchanan IA, Sizdahkhani S, Hurth K, Amba S, Seltzer J, Khan RA, Brunswick AS, Wrobel BB, Zada G. PMID: 32449957.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    21. Hemorrhagic Presentation of Rathke Cleft Cysts: A Surgical Case Series. Oper Neurosurg (Hagerstown). 2020 05 01; 18(5):470-479. Schooner L, Wedemeyer MA, Bonney PA, Lin M, Hurth K, Mathew A, Liu CJ, Shiroishi M, Carmichael JD, Weiss MH, Zada G. PMID: 31504863.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    22. Ultra-high field magnetic resonance imaging for localization of corticotropin-secreting pituitary adenomas. Neuroradiology. 2020 Aug; 62(8):1051-1054. Patel V, Liu CJ, Shiroishi MS, Hurth K, Carmichael JD, Zada G, Toga AW. PMID: 32306052.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. What Genes Can Tell: A Closer Look at Vestibular Schwannoma. Otol Neurotol. 2020 04; 41(4):522-529. Aaron KA, Manojlovic Z, Tu N, Xu Y, Jin Y, Chang S, Kwok E, Webb M, Hurth K, Friedman RA. PMID: 32176142.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    24. Fatal refractory cardiac arrest as presentation of systemic amyloidosis. Respir Med Case Rep. 2020; 30:101042. Chung P, Wheeler S, Fong A, Hurth K, Yaghmour B. PMID: 32274327; PMCID: PMC7132166.
      View in: PubMed   Mentions: 1  
    25. Surgical management of clinically silent thyrotropin pituitary adenomas: A single center series of 20 patients. J Clin Neurosci. 2020 Jan; 71:70-75. Cyprich J, Donoho DA, Brunswick A, Hurth K, Carmichael JD, Weiss MH, Zada G. PMID: 31668712.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. ZBTB16: A new biomarker for primitive neuroectodermal tumor element / Ewing sarcoma. Pathol Res Pract. 2019 Oct; 215(10):152536. Xiao GQ, Sherrod AE, Hurth KM. PMID: 31326195.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    27. Recurrent Rathke's Cleft Cysts: Incidence and Surgical Management in a Tertiary Pituitary Center over 2 Decades. Oper Neurosurg (Hagerstown). 2019 06 01; 16(6):675-684. Wedemeyer MA, Lin M, Fredrickson VL, Arakelyan A, Bradley D, Donoho DA, Hurth KM, Weiss MH, Carmichael JD, Zada G. PMID: 30247673.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    28. Ruptured Mycotic Aneurysm of the Distal Circulation in a Patient with Mucormycosis Without Direct Skull Base Extension: Case Report. Oper Neurosurg (Hagerstown). 2019 03 01; 16(3):E101-E107. Rangwala SD, Strickland BA, Rennert RC, Ravina K, Bakhsheshian J, Hurth K, Giannotta SL, Russin JJ. PMID: 29800469.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Variability and Lack of Prognostic Value Associated With Atypical Pituitary Adenoma Diagnosis: A Systematic Review and Critical Assessment of the Diagnostic Criteria. Neurosurgery. 2018 10 01; 83(4):602-610. Chesney K, Memel Z, Pangal DJ, Donoho D, Hurth K, Mathew A, Carmichael JD, Zada G. PMID: 29165661.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    30. Quadruple Neoplasms following Radiation Therapy for Congenital Bilateral Retinoblastoma. Ocul Oncol Pathol. 2017 Dec; 4(1):33-37. Szymanski LJ, Sibug Saber ME, Kim JW, Go JL, Zada G, Rao N, Hurth KM. PMID: 29344496; PMCID: PMC5757554.
      View in: PubMed   Mentions: 1  
    31. Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model. J Neurosurg. 2018 03; 128(3):695-700. Wang W, Cho HY, Rosenstein-Sisson R, Marín Ramos NI, Price R, Hurth K, Schönthal AH, Hofman FM, Chen TC. PMID: 28409734.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    32. Solitary Plasmacytoma in the Internal Auditory Canal and Cerebellopontine Angle Mimicking Meningioma. Otol Neurotol. 2016 Dec; 37(10):e400-e401. Lavinsky J, Aaron KA, Christian E, Go JL, Hurth K, Giannotta SL, Friedman RA. PMID: 26457817.
      View in: PubMed   Mentions: 2     Fields:    
    33. "Pistachio" and "Avatar" Green-Blue Discoloration of the Brain. Acad Forensic Pathol. 2016 Mar; 6(1):150-152. Szymanski LJ, Hurth K. PMID: 31239883; PMCID: PMC6474518.
      View in: PubMed   Mentions: 1  
    34. Congenital Acute Myeloid Leukemia with Unique Translocation t(11;19)(q23;p13.3). Cureus. 2015 Jul; 7(7):e289. Yarbrough CK, Bandt SK, Hurth K, Wambach JA, Rao R, Kulkarni S, White FV, Frater JL, Leonard JR. PMID: 26244121; PMCID: PMC4523210.
      View in: PubMed   Mentions:
    35. Whipple's disease masquerades as dementia with Lewy bodies. Alzheimer Dis Assoc Disord. 2015 Jan-Mar; 29(1):85-89. Hurth K, Tarawneh R, Ghoshal N, Benzinger TLS, Clifford DB, Geschwind M, Morris JC, Galvin JE, Schmidt RE, Cairns NJ. PMID: 23995819; PMCID: PMC3938990.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    36. A quantitative study of α-synuclein pathology in fifteen cases of dementia associated with Parkinson disease. J Neural Transm (Vienna). 2014 Feb; 121(2):171-81. Armstrong RA, Kotzbauer PT, Perlmutter JS, Campbell MC, Hurth KM, Schmidt RE, Cairns NJ. PMID: 23996276; PMCID: PMC4041534.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    37. Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: a case report. J Med Case Rep. 2012 Oct 08; 6:341. Funk RK, Ferraro DJ, Perrin RJ, Hurth KM, Stephens JJ, Mansur DB, Chicoine MR, Simpson JR, Jaboin JJ. PMID: 23043797; PMCID: PMC3492086.
      View in: PubMed   Mentions: 1     Fields:    
    38. Acute presentation of tophaceous myelopathy. J Rheumatol. 2011 Jul; 38(7):1525-6. Levin E, Hurth K, Joshi R, Brasington R. PMID: 21724731.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Bronchial atresia. Radiographics. 2009 Sep-Oct; 29(5):1531-5. Gipson MG, Cummings KW, Hurth KM. PMID: 19755610.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    40. Ligand-induced changes in estrogen receptor conformation as measured by site-directed spin labeling. Biochemistry. 2004 Feb 24; 43(7):1891-907. Hurth KM, Nilges MJ, Carlson KE, Tamrazi A, Belford RL, Katzenellenbogen JA. PMID: 14967030.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    41. Rapid HPLC screening method for contaminants found in implicated L-tryptophan associated with eosinophilia myalgia syndrome and adulterated rapeseed oil associated with toxic oil syndrome. Biomed Chromatogr. 1998 Sep-Oct; 12(5):255-61. Williamson BL, Tomlinson AJ, Hurth KM, Posada de la Paz M, Gleich GJ, Naylor S. PMID: 9787895.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansPHPublic Health