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Joseph Leo Wiemels, PhD

Title(s)Professor of Preventive Medicine
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    Collapse Biography 
    Collapse Education and Training
    Kenyon College, Gambier, OHBA05/1988Biology
    University of California, Berkeley, Berkeley CAPhD05/1997Toxicology
    Institute of Cancer Research, London, UKPostdoctoral1999Molecular etiology of leukemia

    Collapse Overview 
    Collapse Overview
    The causes of most human cancers are unclear, but appear to be related to miscues in normal tissue developmental pathways, mutations (genetic and epigenetic) in critical genes caused by errors, infection, and chemicals, and a failure of recognition and removal of tumors by the immune system. Dr. Wiemels studies these factors as potential causes of hematopoietic and brain tumors. Large population-based studies of human cancer in California populations form a basis for examining the origin of these cancers, with a focus on future prevention. This type of research is highly collaborative, and Dr. Wiemels works with several epidemiologists, geneticists, clinicians, biologists, and statisticians.

    Collapse Research 
    Collapse Research Activities and Funding
    Immune epigenetic biomarkers of survival in glioma epidemiology
    NIH/NCI R01CA207360Aug 1, 2017 - Jul 31, 2022
    Role: Co-Investigator
    Brain Tumor Epidemiology in the Era of Precision Medicine
    NIH/NCI R13CA221308Jun 27, 2017 - May 31, 2018
    Role: Principal Investigator
    Brain Tumor Epidemiology Consortium
    NIH/NCI R13CA206359Apr 1, 2016 - Mar 31, 2017
    Role: Principal Investigator
    Genetic Susceptibility to Pediatric Glioma inIndividuals and Diverse populations
    NIH/NCI R01CA194189Sep 9, 2015 - Jan 31, 2021
    Role: Principal Investigator
    Perinatal immune development and risk of childhood acute lymphoblastic leukemia
    NIH/NCI R01CA175737Aug 1, 2014 - Jul 31, 2019
    Role: Principal Investigator
    Impact of low IL-10 levels at birth and leukemia risk
    NIH/NCI R01CA185058Jun 1, 2014 - May 31, 2019
    Role: Principal Investigator
    Varicella virus antigens in glioma etiology and survival
    NIH/NCI U01CA182371Mar 6, 2014 - Jan 31, 2018
    Role: Principal Investigator
    Genome-Wide Association Study of Childhood Leukemia by Hispanic Status
    NIH/NCI R01CA155461Jul 1, 2011 - Apr 30, 2015
    Role: Principal Investigator
    Meningioma: Risk Factors and Quality of Life
    NIH/NCI R01CA109745Jun 26, 2006 - Mar 31, 2011
    Role: Principal Investigator
    BACKTRACKING TRANSLOCATIONS IN CHILDHOOD LEUKEMIA
    NIH/NCI R01CA089032Mar 2, 2001 - Feb 28, 2004
    Role: Principal Investigator

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