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Shohreh F Farzan

Title(s)Assistant Professor of Preventive Medicine
Phone+1 323 442 5101
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    The Salton Sea and Children's Health: Assessing Imperial Valley Respiratory Health and the Environment
    NIH/NIEHS R01ES029598Jul 15, 2018 - Apr 30, 2023
    Role: Principal Investigator
    Preclinical Indicators & Biomarkers of Cardiovascular Effects of Arsenic Exposure
    NIH/NIEHS R00ES024144Aug 1, 2016 - Jul 31, 2019
    Role: Principal Investigator
    PRECLINICAL INDICATORS &BIOMARKERS OF CARDIOVASCULAR EFFECTS OF ARSENIC EXPOSURE
    NIH/NIEHS K99ES024144Sep 17, 2014 - Aug 31, 2016
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Farzan SF, Razafy M, Eckel SP, Olmedo L, Bejarano E, Johnston JE. Assessment of Respiratory Health Symptoms and Asthma in Children near a Drying Saline Lake. Int J Environ Res Public Health. 2019 10 11; 16(20). PMID: 31614424.
      View in: PubMed
    2. Bastain TM, Chavez T, Habre R, Girguis MS, Grubbs B, Toledo-Corral C, Amadeus M, Farzan SF, Al-Marayati L, Lerner D, Noya D, Quimby A, Twogood S, Wilson M, Chatzi L, Cousineau M, Berhane K, Eckel SP, Lurmann F, Johnston J, Dunton GF, Gilliland F, Breton C. Study Design, Protocol and Profile of the Maternal And Developmental Risks from Environmental and Social Stressors (MADRES) Pregnancy Cohort: a Prospective Cohort Study in Predominantly Low-Income Hispanic Women in Urban Los Angeles. BMC Pregnancy Childbirth. 2019 May 30; 19(1):189. PMID: 31146718.
      View in: PubMed
    3. O'Connor SG, Habre R, Bastain TM, Toledo-Corral CM, Gilliland FD, Eckel SP, Cabison J, Naya CH, Farzan SF, Chu D, Chavez TA, Breton CV, Dunton GF. Within-subject effects of environmental and social stressors on pre- and post-partum obesity-related biobehavioral responses in low-income Hispanic women: protocol of an intensive longitudinal study. BMC Public Health. 2019 Feb 28; 19(1):253. PMID: 30819155.
      View in: PubMed
    4. Johnston JE, Razafy M, Lugo H, Olmedo L, Farzan SF. The disappearing Salton Sea: A critical reflection on the emerging environmental threat of disappearing saline lakes and potential impacts on children's health. Sci Total Environ. 2019 May 01; 663:804-817. PMID: 30738261.
      View in: PubMed
    5. Farzan SF, Howe CG, Chen Y, Gilbert-Diamond D, Cottingham KL, Jackson BP, Weinstein AR, Karagas MR. Prenatal lead exposure and elevated blood pressure in children. Environ Int. 2018 12; 121(Pt 2):1289-1296. PMID: 30389381.
      View in: PubMed
    6. Moon KA, Oberoi S, Barchowsky A, Chen Y, Guallar E, Nachman KE, Rahman M, Sohel N, D'Ippoliti D, Wade TJ, James KA, Farzan SF, Karagas MR, Ahsan H, Navas-Acien A. A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease. Int J Epidemiol. 2018 04 25. PMID: 29697784.
      View in: PubMed
    7. Farzan SF, Howe CG, Zens MS, Palys T, Channon JY, Li Z, Chen Y, Karagas MR. Urine Arsenic and Arsenic Metabolites in U.S. Adults and Biomarkers of Inflammation, Oxidative Stress, and Endothelial Dysfunction: A Cross-Sectional Study. Environ Health Perspect. 2017 12 15; 125(12):127002. PMID: 29373859.
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    8. Zhou H, Li XI, Kim JH, Salam MT, Kim HB, McConnell RS, Habre R, Bastain T, Farzan SF, Johnston J, Gilliland FD. Effect of inhaled allergens and air pollutants on childhood rhinitis development. Ann Allergy Asthma Immunol. 2018 02; 120(2):212-214. PMID: 29217086.
      View in: PubMed
    9. Moon KA, Oberoi S, Barchowsky A, Chen Y, Guallar E, Nachman KE, Rahman M, Sohel N, D'Ippoliti D, Wade TJ, James KA, Farzan SF, Karagas MR, Ahsan H, Navas-Acien A. A dose-response meta-analysis of chronic arsenic exposure and incident cardiovascular disease. Int J Epidemiol. 2017 12 01; 46(6):1924-1939. PMID: 29040626.
      View in: PubMed
    10. Howe CG, Li Z, Zens MS, Palys T, Chen Y, Channon JY, Karagas MR, Farzan SF. Dietary B Vitamin Intake Is Associated with Lower Urinary Monomethyl Arsenic and Oxidative Stress Marker 15-F2t-Isoprostane among New Hampshire Adults. J Nutr. 2017 12; 147(12):2289-2296. PMID: 29070711.
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    11. Farzan SF, Brickley EB, Li Z, Gilbert-Diamond D, Gossai A, Chen Y, Howe CG, Palys T, Karagas MR. Maternal and infant inflammatory markers in relation to prenatal arsenic exposure in a U.S. pregnancy cohort. Environ Res. 2017 07; 156:426-433. PMID: 28410520.
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    12. Farzan SF, Gossai A, Chen Y, Chasan-Taber L, Baker E, Karagas M. Maternal arsenic exposure and gestational diabetes and glucose intolerance in the New Hampshire birth cohort study. Environ Health. 2016 11 08; 15(1):106. PMID: 27825389.
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    13. Madan JC, Hoen AG, Lundgren SN, Farzan SF, Cottingham KL, Morrison HG, Sogin ML, Li H, Moore JH, Karagas MR. Association of Cesarean Delivery and Formula Supplementation With the Intestinal Microbiome of 6-Week-Old Infants. JAMA Pediatr. 2016 Mar; 170(3):212-9. PMID: 26752321.
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    14. Gossai A, Waterboer T, Hoen AG, Farzan SF, Nelson HH, Michel A, Willhauck-Fleckenstein M, Christensen BC, Perry AE, Pawlita M, Karagas MR. Human polyomaviruses and incidence of cutaneous squamous cell carcinoma in the New Hampshire skin cancer study. Cancer Med. 2016 06; 5(6):1239-50. PMID: 26899857.
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    15. Gossai A, Waterboer T, Nelson HH, Doherty JA, Michel A, Willhauck-Fleckenstein M, Farzan SF, Christensen BC, Hoen AG, Perry AE, Pawlita M, Karagas MR. Prospective Study of Human Polyomaviruses and Risk of Cutaneous Squamous Cell Carcinoma in the United States. Cancer Epidemiol Biomarkers Prev. 2016 05; 25(5):736-44. PMID: 26908434.
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    16. Gossai A, Waterboer T, Nelson HH, Michel A, Willhauck-Fleckenstein M, Farzan SF, Hoen AG, Christensen BC, Kelsey KT, Marsit CJ, Pawlita M, Karagas MR. Seroepidemiology of Human Polyomaviruses in a US Population. Am J Epidemiol. 2016 Jan 01; 183(1):61-9. PMID: 26667254.
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    17. Farzan SF, Chen Y, Trachtman H, Trasande L. Urinary polycyclic aromatic hydrocarbons and measures of oxidative stress, inflammation and renal function in adolescents: NHANES 2003-2008. Environ Res. 2016 Jan; 144(Pt A):149-157. PMID: 26610293.
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    18. Farzan SF, Li Z, Korrick SA, Spiegelman D, Enelow R, Nadeau K, Baker E, Karagas MR. Infant Infections and Respiratory Symptoms in Relation to in Utero Arsenic Exposure in a U.S. Cohort. Environ Health Perspect. 2016 06; 124(6):840-7. PMID: 26359651.
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    19. Farzan SF, Karagas MR, Jiang J, Wu F, Liu M, Newman JD, Jasmine F, Kibriya MG, Paul-Brutus R, Parvez F, Argos M, Scannell Bryan M, Eunus M, Ahmed A, Islam T, Rakibuz-Zaman M, Hasan R, Sarwar G, Slavkovich V, Graziano J, Ahsan H, Chen Y. Gene-arsenic interaction in longitudinal changes of blood pressure: Findings from the Health Effects of Arsenic Longitudinal Study (HEALS) in Bangladesh. Toxicol Appl Pharmacol. 2015 10 01; 288(1):95-105. PMID: 26220686.
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    20. Farzan SF, Chen Y, Rees JR, Zens MS, Karagas MR. Risk of death from cardiovascular disease associated with low-level arsenic exposure among long-term smokers in a US population-based study. Toxicol Appl Pharmacol. 2015 Sep 01; 287(2):93-97. PMID: 26048586.
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    21. Jiang J, Liu M, Parvez F, Wang B, Wu F, Eunus M, Bangalore S, Newman JD, Ahmed A, Islam T, Rakibuz-Zaman M, Hasan R, Sarwar G, Levy D, Slavkovich V, Argos M, Scannell Bryan M, Farzan SF, Hayes RB, Graziano JH, Ahsan H, Chen Y. Association between Arsenic Exposure from Drinking Water and Longitudinal Change in Blood Pressure among HEALS Cohort Participants. Environ Health Perspect. 2015 08; 123(8):806-12. PMID: 25816368.
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    22. Farzan SF, Chen Y, Wu F, Jiang J, Liu M, Baker E, Korrick SA, Karagas MR. Blood Pressure Changes in Relation to Arsenic Exposure in a U.S. Pregnancy Cohort. Environ Health Perspect. 2015 Oct; 123(10):999-1006. PMID: 25793356.
      View in: PubMed
    23. Carignan CC, Cottingham KL, Jackson BP, Farzan SF, Gandolfi AJ, Punshon T, Folt CL, Karagas MR. Estimated exposure to arsenic in breastfed and formula-fed infants in a United States cohort. Environ Health Perspect. 2015 May; 123(5):500-6. PMID: 25707031.
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    24. Farzan SF, Robbins DJ. Quantitative Immunoblotting of Endogenous Hedgehog Pathway Components. Methods Mol Biol. 2015; 1322:93-104. PMID: 26179042.
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    25. Gossai A, Lesseur C, Farzan S, Marsit C, Karagas MR, Gilbert-Diamond D. Association between maternal urinary arsenic species and infant cord blood leptin levels in a New Hampshire Pregnancy Cohort. Environ Res. 2015 Jan; 136:180-6. PMID: 25460635.
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    26. Nadeau KC, Li Z, Farzan S, Koestler D, Robbins D, Fei DL, Malipatlolla M, Maecker H, Enelow R, Korrick S, Karagas MR. In utero arsenic exposure and fetal immune repertoire in a US pregnancy cohort. Clin Immunol. 2014 Dec; 155(2):188-97. PMID: 25229165.
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    27. Farzan SF, Karagas MR, Christensen BC, Li Z, Kuriger JK, Nelson HH. RNASEL and MIR146A SNP-SNP interaction as a susceptibility factor for non-melanoma skin cancer. PLoS One. 2014; 9(4):e93602. PMID: 24699816.
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    28. Farzan SF, Karagas MR, Chen Y. In utero and early life arsenic exposure in relation to long-term health and disease. Toxicol Appl Pharmacol. 2013 Oct 15; 272(2):384-90. PMID: 23859881.
      View in: PubMed
    29. Farzan SF, Korrick S, Li Z, Enelow R, Gandolfi AJ, Madan J, Nadeau K, Karagas MR. In utero arsenic exposure and infant infection in a United States cohort: a prospective study. Environ Res. 2013 Oct; 126:24-30. PMID: 23769261.
      View in: PubMed
    30. Farzan SF, Waterboer T, Gui J, Nelson HH, Li Z, Michael KM, Perry AE, Spencer SK, Demidenko E, Green AC, Pawlita M, Karagas MR. Cutaneous alpha, beta and gamma human papillomaviruses in relation to squamous cell carcinoma of the skin: a population-based study. Int J Cancer. 2013 Oct 01; 133(7):1713-20. PMID: 23536363.
      View in: PubMed
    31. Madan JC, Farzan SF, Hibberd PL, Karagas MR. Normal neonatal microbiome variation in relation to environmental factors, infection and allergy. Curr Opin Pediatr. 2012 Dec; 24(6):753-9. PMID: 23111681.
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    32. Ghaffari SR, Tahmasebpour AR, Jamal A, Hantoushzadeh S, Eslamian L, Marsoosi V, Fattahi F, Rajaei M, Niroomanesh S, Borna S, Beigi A, Khazardoost S, Saleh-Gargari S, Rahimi-Sharbaf F, Farrokhi B, Bayani N, Tehrani SE, Shahsavan K, Farzan S, Moossavi S, Ramezanzadeh F, Dastan J, Rafati M. First-trimester screening for chromosomal abnormalities by integrated application of nuchal translucency, nasal bone, tricuspid regurgitation and ductus venosus flow combined with maternal serum free ß-hCG and PAPP-A: a 5-year prospective study. Ultrasound Obstet Gynecol. 2012 May; 39(5):528-34. PMID: 21793085.
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    33. Farzan SF, Palermo LM, Yokoyama CC, Orefice G, Fornabaio M, Sarkar A, Kellogg GE, Greengard O, Porotto M, Moscona A. Premature activation of the paramyxovirus fusion protein before target cell attachment with corruption of the viral fusion machinery. J Biol Chem. 2011 Nov 04; 286(44):37945-54. PMID: 21799008.
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    34. Farzan SF, Ogden SK, Robbins DJ. Quantitative insight into models of Hedgehog signal transduction. Fly (Austin). 2010 Apr-Jun; 4(2):141-4. PMID: 20081354.
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    35. Farzan SF, Stegman MA, Ogden SK, Ascano M, Black KE, Tacchelly O, Robbins DJ. A quantification of pathway components supports a novel model of Hedgehog signal transduction. J Biol Chem. 2009 Oct 16; 284(42):28874-84. PMID: 19717563.
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    36. Farzan SF, Ascano M, Ogden SK, Sanial M, Brigui A, Plessis A, Robbins DJ. Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway. Curr Biol. 2008 Aug 26; 18(16):1215-20. PMID: 18691888.
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    37. Farzan SF, Singh S, Schilling NS, Robbins DJ. The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G844-9. PMID: 18239057.
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    38. Li N, Li H, Cherukuri P, Farzan S, Harmes DC, DiRenzo J. TA-p63-gamma regulates expression of DeltaN-p63 in a manner that is sensitive to p53. Oncogene. 2006 Apr 13; 25(16):2349-59. PMID: 16331262.
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