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DROSHA Regulates Mesenchymal Gene Expression in Wilms Tumor. Mol Cancer Res. 2024 08 02; 22(8):711-720.
Tiburcio PDB, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Xu L, Chen KS. PMID: 38647377; PMCID: PMC11296922.
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1 Fields:
Translation:
HumansCells
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Seed Becoming Soil: A New Paradigm of the Ewing Sarcoma Tumor Microenvironment. Clin Cancer Res. 2023 12 15; 29(24):5002-5004.
Kuo C, Amatruda JF. PMID: 37796143; PMCID: PMC10873080.
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Translation:
HumansCells
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Building advocacy into research. Dis Model Mech. 2023 Dec 01; 16(12).
Amatruda JF. PMID: 38108236; PMCID: PMC10753189.
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PubMed Mentions:
1 Fields:
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Refining the serum miR-371a-3p test for viable germ cell tumor detection. Sci Rep. 2023 06 29; 13(1):10558.
Lafin JT, Scarpini CG, Amini A, Konneh B, Howard JM, Gerald T, Nuno M, Piao J, Savelyeva A, Wang Z, Gagan J, Jia L, Lewis CM, Murray S, Sawa YC, Margulis V, Woldu SL, Strand DW, Coleman N, Amatruda JF, Frazier AL, Murray MJ, Bagrodia A. PMID: 37386046; PMCID: PMC10310745.
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PubMed Mentions: Fields:
Translation:
Humans
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Integrated genomic analysis reveals aberrations in WNT signaling in germ cell tumors of childhood and adolescence. Nat Commun. 2023 05 06; 14(1):2636.
Xu L, Pierce JL, Sanchez A, Chen KS, Shukla AA, Fustino NJ, Stuart SH, Bagrodia A, Xiao X, Guo L, Krailo MD, Shaikh F, Billmire DF, Pashankar F, Bestrashniy J, Oosterhuis JW, Gillis AJM, Xie Y, Teot L, Mora J, Poynter JN, Rakheja D, Looijenga LHJ, Draper BW, Frazier AL, Amatruda JF. PMID: 37149691; PMCID: PMC10164134.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Specifications of the ACMG/AMP Variant Classification Guidelines for Germline DICER1 Variant Curation. Hum Mutat. 2023; 2023.
Hatton JN, Frone MN, Cox HC, Crowley SB, Hiraki S, Yokoyama NN, Abul-Husn NS, Amatruda JF, Anderson MJ, Bofill-De Ros X, Carr AG, Chao EC, Chen KS, Gu S, Higgs C, Machado J, Ritter D, Schultz KA, Soper ER, Wu MK, Mester JL, Kim J, Foulkes WD, Witkowski L, Stewart DR. PMID: 38084291; PMCID: PMC10713350.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Refining the serum miR-371a-3p test for viable germ cell tumor detection: identification and definition of an indeterminate range. Res Sq. 2023 Mar 21.
Lafin J, Scarpini C, Amini A, Konneh B, Howard J, Gerald T, Nuno M, Piao J, Savelyeva A, Wang Z, Gagan J, Jia L, Lewis C, Murray S, Sawa Y, Margulis V, Woldu S, Strand D, Coleman N, Amatruda J, Frazier L, Murray M, Bagrodia A. PMID: 36993198; PMCID: PMC10055551.
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PubMed Mentions:
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Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors. NPJ Precis Oncol. 2023 Feb 20; 7(1):21.
Christodoulou E, Yellapantula V, O'Halloran K, Xu L, Berry JL, Cotter JA, Zdanowicz A, Mascarenhas L, Amatruda JF, Ostrow D, Bootwalla M, Gai X, Navid F, Biegel JA. PMID: 36805676; PMCID: PMC9941464.
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PubMed Mentions:
10
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WILMS TUMOR MUTATIONAL SUBCLASSES CONVERGE TO DRIVE CCND2 OVEREXPRESSION. medRxiv. 2023 Feb 02.
Xu L, Desai K, Kim J, Zhou Q, Guo L, Xiao X, Zhang Y, Zhou L, Yuksel A, Catchpoole DR, Amatruda JF, Chen KS. PMID: 36778325; PMCID: PMC9915828.
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PubMed Mentions:
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VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis. Cell Rep. 2023 01 31; 42(1):112013.
Watson S, LaVigne CA, Xu L, Surdez D, Cyrta J, Calderon D, Cannon MV, Kent MR, Silvius KM, Kucinski JP, Harrison EN, Murchison W, Rakheja D, Tirode F, Delattre O, Amatruda JF, Kendall GC. PMID: 36656711; PMCID: PMC10054615.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Evaluation of miR-371a-3p to predict viable germ cell tumor in patients with pure seminoma receiving retroperitoneal lymph node dissection. Andrology. 2023 05; 11(4):634-640.
Konneh B, Lafin JT, Howard J, Gerald T, Amini A, Savelyeva A, Woldu SL, Lewis CM, Jia L, Margulis V, Coleman N, Scarpini C, Frazier AL, Murray MJ, Amatruda JF, Bagrodia A. PMID: 36254623.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium. Br J Cancer. 2022 11; 127(9):1577-1583.
Fonseca A, Lobo J, Hazard FK, Gell J, Nicholls PK, Weiss RS, Klosterkemper L, Volchenboum SL, Nicholson JC, Frazier AL, Amatruda JF, Bagrodia A, Lockley M, Murray MJ. PMID: 36229581; PMCID: PMC9596690.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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Small round cell sarcomas. Nat Rev Dis Primers. 2022 10 06; 8(1):66.
Cidre-Aranaz F, Watson S, Amatruda JF, Nakamura T, Delattre O, de Alava E, Dirksen U, Grünewald TGP. PMID: 36202860.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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In vivo 3D profiling of site-specific human cancer cell morphotypes in zebrafish. J Cell Biol. 2022 11 07; 221(11).
Segal D, Mazloom-Farsibaf H, Chang BJ, Roudot P, Rajendran D, Daetwyler S, Fiolka R, Warren M, Amatruda JF, Danuser G. PMID: 36155740; PMCID: PMC9516844.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Response to commentary re: Clinicopathologic predictors of outcomes in children with stage I testicular germ cell tumors: A pooled post hoc analysis of trials from the Children's oncology group. J Pediatr Urol. 2022 08; 18(4):513-514.
Singla N, Wong J, Singla S, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda JF, Frazier AL, Bagrodia A. PMID: 35868999.
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PubMed Mentions: Fields:
Translation:
Humans
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Clinicopathologic predictors of outcomes in children with stage I testicular germ cell tumors: A pooled post hoc analysis of trials from the Children's Oncology Group. J Pediatr Urol. 2022 08; 18(4):505-511.
Singla N, Wong J, Singla S, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda JF, Lindsay Frazier A, Bagrodia A. PMID: 35606324; PMCID: PMC9667350.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth. Elife. 2022 03 14; 11.
Vasileva E, Warren M, Triche TJ, Amatruda JF. PMID: 35285802; PMCID: PMC8942468.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimals
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Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial. Pediatr Blood Cancer. 2022 02; 69(2):e29451.
Yang A, Patterson A, Pavlock T, Chen KS, Gagan J, Hatley ME, Frazier AL, Amatruda JF, Laetsch TW, Rakheja D. PMID: 34866303; PMCID: PMC9359435.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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A Multi-institutional Pooled Analysis Demonstrates That Circulating miR-371a-3p Alone is Sufficient for Testicular Malignant Germ Cell Tumor Diagnosis. Clin Genitourin Cancer. 2021 12; 19(6):469-479.
Piao J, Lafin JT, Scarpini CG, Nuño MM, Syring I, Dieckmann KP, Belge G, Ellinger J, Amatruda JF, Bagrodia A, Coleman N, Krailo MD, Frazier AL, Murray MJ. PMID: 34629299; PMCID: PMC9084514.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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The developmental origin of cancers defines basic principles of cisplatin resistance. Cancer Lett. 2021 10 28; 519:199-210.
Skowron MA, Oing C, Bremmer F, Ströbel P, Murray MJ, Coleman N, Amatruda JF, Honecker F, Bokemeyer C, Albers P, Nettersheim D. PMID: 34320371.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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The Road Ahead for Circulating microRNAs in Diagnosis and Management of Testicular Germ Cell Tumors. Mol Diagn Ther. 2021 05; 25(3):269-271.
Lafin JT, Murray MJ, Coleman N, Frazier AL, Amatruda JF, Bagrodia A. PMID: 33893623.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives. J Clin Med. 2021 Apr 14; 10(8).
Zöllner SK, Amatruda JF, Bauer S, Collaud S, de Álava E, DuBois SG, Hardes J, Hartmann W, Kovar H, Metzler M, Shulman DS, Streitbürger A, Timmermann B, Toretsky JA, Uhlenbruch Y, Vieth V, Grünewald TGP, Dirksen U. PMID: 33919988; PMCID: PMC8071040.
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PubMed Mentions:
69
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Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force. J Clin Med. 2021 Apr 01; 10(7).
Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, Meyer WH, Hawkins DS, Chen EY, Amatruda JF, Hingorani P, Laetsch TW. PMID: 33915882; PMCID: PMC8037615.
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PubMed Mentions:
11
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RAD21 is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress. Genes Dev. 2021 04 01; 35(7-8):556-572.
Su XA, Ma D, Parsons JV, Replogle JM, Amatruda JF, Whittaker CA, Stegmaier K, Amon A. PMID: 33766983; PMCID: PMC8015718.
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PubMed Mentions:
21 Fields:
Translation:
HumansCells
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Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection. Eur Urol Open Sci. 2021 Apr; 26:83-87.
Lafin JT, Kenigsberg AP, Meng X, Abe D, Savelyeva A, Singla N, Woldu SL, Lotan Y, Mauck RJ, Lewis CM, Margulis V, Wong D, Jia L, Kapur P, Xu L, Speir RW, Chesnut GT, Frazier AL, Strand DW, Coleman N, Murray MJ, Amatruda JF, Bagrodia A. PMID: 33997822; PMCID: PMC8121258.
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PubMed Mentions:
18
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Neonatal Malignant Disorders: Germ Cell Tumors. Clin Perinatol. 2021 03; 48(1):147-165.
Shah R, Weil BR, Weldon CB, Amatruda JF, Frazier AL. PMID: 33583501.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Modeling the developmental origins of pediatric cancer to improve patient outcomes. Dis Model Mech. 2021 02 22; 14(2).
Amatruda JF. PMID: 33619212; PMCID: PMC7927656.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Germ Cell Tumor Cell Culture Techniques. Methods Mol Biol. 2021; 2195:65-76.
Lafin JT, Amatruda JF, Bagrodia A. PMID: 32852757.
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Translation:
HumansCells
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Correction to: Germ Cell Tumor Cell Culture Techniques. Methods Mol Biol. 2021; 2195:C1.
Lafin JT, Amatruda JF, Bagrodia A. PMID: 34453282.
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Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. Methods Mol Biol. 2021; 2195:263-275.
Ci B, Lin SY, Yao B, Luo D, Xu L, Krailo M, Murray MJ, Amatruda JF, Frazier AL, Xie Y. PMID: 32852769.
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Translation:
Humans
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Publisher Correction: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. Nat Commun. 2020 Nov 23; 11(1):6068.
Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, Romero-Pérez L, Hölting TLB, Amatruda JF, Cossarizza A, Henssen AG, Kirchner T, Moretti M, Cidre-Aranaz F, Sannino G, Grünewald TGP. PMID: 33230121; PMCID: PMC7683734.
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PubMed Mentions: Fields:
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Impact of circulating microRNA test (miRNA-371a-3p) on appropriateness of treatment and cost outcomes in patients with Stage I non-seminomatous germ cell tumours. BJU Int. 2021 07; 128(1):57-64.
Bagrodia A, Savelyeva A, Lafin JT, Speir RW, Chesnut GT, Frazier AL, Woldu SL, Margulis V, Murray MJ, Amatruda JF, Lotan Y. PMID: 33124175.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Outcomes of adolescent males with extracranial metastatic germ cell tumors: A report from the Malignant Germ Cell Tumor International Consortium. Cancer. 2021 01 15; 127(2):193-202.
Shaikh F, Stark D, Fonseca A, Dang H, Xia C, Krailo M, Pashankar F, Rodriguez-Galindo C, Olson TA, Nicholson JC, Murray MJ, Amatruda JF, Billmire D, Stoneham S, Frazier AL. PMID: 33079404.
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PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Real-World Application of Pre-Orchiectomy miR-371a-3p Test in Testicular Germ Cell Tumor Management. J Urol. 2021 Jan; 205(1):137-144.
Badia RR, Abe D, Wong D, Singla N, Savelyeva A, Chertack N, Woldu SL, Lotan Y, Mauck R, Ouyang D, Meng X, Lewis CM, Majmudar K, Jia L, Kapur P, Xu L, Frazier AL, Margulis V, Strand DW, Coleman N, Murray MJ, Amatruda JF, Lafin JT, Bagrodia A. PMID: 32856980.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
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Development of a Data Model and Data Commons for Germ Cell Tumors. JCO Clin Cancer Inform. 2020 06; 4:555-566.
Ci B, Yang DM, Krailo M, Xia C, Yao B, Luo D, Zhou Q, Xiao G, Xu L, Skapek SX, Murray MM, Amatruda JF, Klosterkemper L, Shaikh F, Faure-Conter C, Fresneau B, Volchenboum SL, Stoneham S, Lopes LF, Nicholson J, Frazier AL, Xie Y. PMID: 32568554; PMCID: PMC7328105.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma. Nat Commun. 2020 05 15; 11(1):2423.
Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, Romero-Pérez L, Hölting TLB, Amatruda JF, Cossarizza A, Henssen AG, Kirchner T, Moretti M, Cidre-Aranaz F, Sannino G, Grünewald TGP. PMID: 32415069; PMCID: PMC7228971.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Birth Characteristics and Risk of Early-Onset Synovial Sarcoma. Cancer Epidemiol Biomarkers Prev. 2020 06; 29(6):1162-1167.
Wiemels JL, Wiemels JL, Wang R, Feng Q, Clark CJ, Amatruda JF, Rubin E, Yee AC, Morimoto LM, Metayer C, Ma X. PMID: 32245786; PMCID: PMC7605594.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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GCNA Preserves Genome Integrity and Fertility Across Species. Dev Cell. 2020 01 06; 52(1):38-52.e10.
Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, Yanowitz JL, Buszczak M. PMID: 31839537; PMCID: PMC6946843.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Serum MicroRNA-371a-3p Levels Predict Viable Germ Cell Tumor in Chemotherapy-naïve Patients Undergoing Retroperitoneal Lymph Node Dissection. Eur Urol. 2020 02; 77(2):290-292.
Lafin JT, Singla N, Woldu SL, Lotan Y, Lewis CM, Majmudar K, Savelyeva A, Kapur P, Margulis V, Strand DW, Murray MJ, Amatruda JF, Bagrodia A. PMID: 31699528; PMCID: PMC7756387.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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α-Fetoprotein as a predictor of outcome for children with germ cell tumors: A report from the Malignant Germ Cell International Consortium. Cancer. 2019 10 15; 125(20):3649-3656.
O'Neill AF, Xia C, Krailo MD, Shaikh F, Pashankar FD, Billmire DF, Olson TA, Amatruda JF, Villaluna D, Huang L, Malogolowkin M, Rodriguez-Galindo C, Frazier AL. PMID: 31355926.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
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Genetics of testicular germ cell tumors. Curr Opin Urol. 2019 07; 29(4):344-349.
Singla N, Lafin JT, Ghandour RA, Kaffenberger S, Amatruda JF, Bagrodia A. PMID: 31045925; PMCID: PMC6659740.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Identification of testicular cancer driver genes by a cross-species comparative oncology approach. Andrology. 2019 07; 7(4):545-554.
Sanchez A, Xu L, Pierce JL, Lafin JT, Abe D, Bagrodia A, Frazier AL, Amatruda JF. PMID: 31087453; PMCID: PMC7500825.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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New insights into germ cell tumor genomics. Andrology. 2019 07; 7(4):507-515.
Lafin JT, Bagrodia A, Woldu S, Amatruda JF. PMID: 30896089.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2019 02 10; 37(5):396-402.
Fonseca A, Xia C, Lorenzo AJ, Krailo M, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Billmire DF, Rodriguez-Galindo C, Frazier AL, Shaikh F. PMID: 30576269; PMCID: PMC6553816.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish. Dev Dyn. 2019 02; 248(2):173-188.
Bhakta M, Padanad MS, Harris JP, Lubczyk C, Amatruda JF, Munshi NV. PMID: 30444277; PMCID: PMC6340724.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 10; 119(7):864-872.
Williams LA, Mills L, Hooten AJ, Langer E, Roesler M, Frazier AL, Krailo M, Nelson HH, Bestrashniy J, Amatruda JF, Poynter JN. PMID: 30287918; PMCID: PMC6189207.
View in:
PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Klinefelter syndrome in males with germ cell tumors: A report from the Children's Oncology Group. Cancer. 2018 10 01; 124(19):3900-3908.
Williams LA, Pankratz N, Lane J, Krailo M, Roesler M, Richardson M, Frazier AL, Amatruda JF, Poynter JN. PMID: 30291793; PMCID: PMC6241518.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
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Mutations in microRNA processing genes in Wilms tumors derepress the IGF2 regulator PLAG1. Genes Dev. 2018 08 01; 32(15-16):996-1007.
Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF. PMID: 30026293; PMCID: PMC6075147.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes. Cell Rep. 2018 07 03; 24(1):238-251.
Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX. PMID: 29972784; PMCID: PMC7293769.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Practice Patterns and Impact of Postchemotherapy Retroperitoneal Lymph Node Dissection on Testicular Cancer Outcomes. Eur Urol Oncol. 2018 08; 1(3):242-251.
Woldu SL, Moore JA, Ci B, Freifeld Y, Clinton TN, Aydin AM, Singla N, Laura-Maria K, Hutchinson RC, Amatruda JF, Sagalowsky A, Lotan Y, Arriaga Y, Margulis V, Xie Y, Bagrodia A. PMID: 31058267; PMCID: PMC6494089.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. Elife. 2018 06 05; 7.
Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. PMID: 29869612; PMCID: PMC5988421.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecol Oncol. 2018 08; 150(2):253-260.
Shah R, Xia C, Krailo M, Amatruda JF, Arul SG, Billmire DF, Brady WE, Covens A, Gershenson DM, Hale JP, Hurteau J, Murray MJ, Nicholson JC, Olson TA, Pashankar F, Rodriguez-Galindo C, Shaikh F, Stark D, Frazier AL, Stoneham S. PMID: 29884437.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium. Eur J Cancer. 2018 07; 98:30-37.
Frazier AL, Stoneham S, Rodriguez-Galindo C, Dang H, Xia C, Olson TA, Murray MJ, Amatruda JF, Shaikh F, Pashankar F, Billmire D, Krailo M, Stark D, Brougham MFH, Nicholson JC, Hale JP. PMID: 29859339.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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Distinct DICER1 Hotspot Mutations Identify Bilateral Tumors as Separate Events. JCO Precis Oncol. 2018; 2.
Chen KS, Stuart SH, Stroup EK, Shukla AS, Wang J, Rajaram V, Vujanic GM, Slone T, Rakheja D, Amatruda JF. PMID: 31893257; PMCID: PMC6938390.
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PubMed Mentions:
8 Fields:
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EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors. Mol Cancer Ther. 2018 05; 17(5):1079-1089.
Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF. PMID: 29483210; PMCID: PMC5932259.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Pediatric Germ Cell Tumors: A Developmental Perspective. Adv Urol. 2018; 2018:9059382.
Pierce JL, Frazier AL, Amatruda JF. PMID: 29515628; PMCID: PMC5817207.
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PubMed Mentions:
33
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Adolescents and Young Adults With a "Rare" Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors. Oncologist. 2018 02; 23(2):272.
Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, Nicholson JC, Gershenson D, Frazier AL. PMID: 29449513; PMCID: PMC5813761.
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PubMed Mentions:
1 Fields:
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Gonadal dysgenesis is associated with worse outcomes in patients with ovarian nondysgerminomatous tumors: A report of the Children's Oncology Group AGCT 0132 study. Pediatr Blood Cancer. 2018 04; 65(4).
Dicken BJ, Billmire DF, Krailo M, Xia C, Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Rescorla FJ, Egler RA, Ross JH, Rodriguez-Galindo C, Frazier AL. PMID: 29286555; PMCID: PMC6219870.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
-
Differences at Presentation and Treatment of Testicular Cancer in Hispanic Men: Institutional and National Hospital-based Analyses. Urology. 2018 02; 112:103-111.
Woldu SL, Aydin AM, Rao AV, Hutchinson RC, Singla N, Clinton TN, Krabbe LM, Passoni NM, Raj GV, Miller DS, Amatruda JF, Sagalowsky AI, Lotan Y, Arriaga Y, Margulis V, Bagrodia A. PMID: 29079210.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Erratum: Publisher Correction: Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nat Commun. 2017; 8:16177.
Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. PMID: 31305780; PMCID: PMC5717037.
View in:
PubMed Mentions: Fields:
-
Family history of cancer in children and adolescents with germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 01; 118(1):121-126.
Poynter JN, Richardson M, Roesler M, Krailo M, Amatruda JF, Frazier AL. PMID: 29065103; PMCID: PMC5765220.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. Curr Biol. 2017 Oct 09; 27(19):3010-3016.e3.
Tiwari B, Kurtz P, Jones AE, Wylie A, Amatruda JF, Boggupalli DP, Gonsalvez GB, Abrams JM. PMID: 28966088; PMCID: PMC5639916.
View in:
PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
-
C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells. Oncotarget. 2017 Apr 18; 8(16):26013-26026.
Gardiner JD, Abegglen LM, Huang X, Carter BE, Schackmann EA, Stucki M, Paxton CN, Lor Randall R, Amatruda JF, Putnam AR, Kovar H, Lessnick SL, Schiffman JD. PMID: 28148901; PMCID: PMC5432234.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansCells
-
Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group. Genes Chromosomes Cancer. 2017 07; 56(7):548-558.
Marcotte EL, Pankratz N, Amatruda JF, Frazier AL, Krailo M, Davies S, Starr JR, Lau CC, Roesler M, Langer E, Hallstrom C, Hooten AJ, Poynter JN. PMID: 28295819; PMCID: PMC5612339.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2017 Apr 10; 35(11):1203-1210.
Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Villaluna D, Krailo M, Billmire DF, Rescorla FJ, Egler RA, Dicken BJ, Ross JH, Schlatter M, Rodriguez-Galindo C, Frazier AL. PMID: 28240974; PMCID: PMC5455599.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCTClinical Trials
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Risk of second malignant neoplasms in women and girls with germ cell tumors. Ann Oncol. 2017 02 01; 28(2):329-332.
Liao Z, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. PMID: 27864217.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):1649-1654.
Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L. PMID: 28143939; PMCID: PMC5320972.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimalsCells
-
Testicular germ cell tumor genomics. Curr Opin Urol. 2017 01; 27(1):41-47.
Woldu SL, Amatruda JF, Bagrodia A. PMID: 27584029; PMCID: PMC6368344.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nat Med. 2017 01; 23(1):79-90.
Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. PMID: 27941793; PMCID: PMC6956990.
View in:
PubMed Mentions:
67 Fields:
Translation:
HumansAnimalsCells
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Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis. Oncotarget. 2016 10 18; 7(42):67919-67933.
Lee E, Wei Y, Zou Z, Tucker K, Rakheja D, Levine B, Amatruda JF. PMID: 27655644; PMCID: PMC5356529.
View in:
PubMed Mentions:
11 Fields:
Translation:
Animals
-
Bmp15 Is an Oocyte-Produced Signal Required for Maintenance of the Adult Female Sexual Phenotype in Zebrafish. PLoS Genet. 2016 09; 12(9):e1006323.
Dranow DB, Hu K, Bird AM, Lawry ST, Adams MT, Sanchez A, Amatruda JF, Draper BW. PMID: 27642754; PMCID: PMC5028036.
View in:
PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Risk of second gonadal cancers in women and children with germ cell tumors. Cancer. 2016 07 01; 122(13):2076-82.
Liao ZW, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. PMID: 27152727.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Paediatric extracranial germ-cell tumours. Lancet Oncol. 2016 04; 17(4):e149-e162.
Shaikh F, Murray MJ, Amatruda JF, Coleman N, Nicholson JC, Hale JP, Pashankar F, Stoneham SJ, Poynter JN, Olson TA, Billmire DF, Stark D, Rodriguez-Galindo C, Frazier AL. PMID: 27300675.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease. Oncotarget. 2016 Feb 23; 7(8):8613-24.
Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, Lawlor E, Lessnick S, Ludwig J, Meltzer P, Metzler M, Mora J, Moriggl R, Nakamura T, Papamarkou T, Radic Sarikas B, Rédini F, Richter GH, Rossig C, Schadler K, Schäfer BW, Scotlandi K, Sheffield NC, Shelat A, Snaar-Jagalska E, Sorensen P, Stegmaier K, Stewart E, Sweet-Cordero A, Szuhai K, Tirado OM, Tirode F, Toretsky J, Tsafou K, Üren A, Zinovyev A, Delattre O. PMID: 26802024; PMCID: PMC4890991.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Zebrafish as a Model for the Study of Solid Malignancies. Methods Mol Biol. 2016; 1451:121-42.
Kendall GC, Amatruda JF. PMID: 27464805.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Zebrafish Germ Cell Tumors. Adv Exp Med Biol. 2016; 916:479-94.
Sanchez A, Amatruda JF. PMID: 27165367; PMCID: PMC4959914.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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Biochemical Analysis of Tankyrase Activity in Zebrafish In Vitro and In Vivo. Methods Mol Biol. 2016; 1481:95-100.
Moon J, Amatruda JF. PMID: 27590155.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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p53 genes function to restrain mobile elements. Genes Dev. 2016 Jan 01; 30(1):64-77.
Wylie A, Jones AE, D'Brot A, Lu WJ, Kurtz P, Moran JV, Rakheja D, Chen KS, Hammer RE, Comerford SA, Amatruda JF, Abrams JM. PMID: 26701264; PMCID: PMC4701979.
View in:
PubMed Mentions:
101 Fields:
Translation:
HumansAnimalsCells
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Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nat Commun. 2015 Nov 17; 6:8891.
Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, Amatruda JF, Nuchtern JG, Chintagumpala MM, Wheeler DA, Plon SE, Sumazin P, Parsons DW. PMID: 26573325; PMCID: PMC4660214.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer. 2016 Jan 15; 122(2):230-7.
Pashankar F, Hale JP, Dang H, Krailo M, Brady WE, Rodriguez-Galindo C, Nicholson JC, Murray MJ, Bilmire DF, Stoneham S, Arul GS, Olson TA, Stark D, Shaikh F, Amatruda JF, Covens A, Gershenson DM, Frazier AL. PMID: 26485622; PMCID: PMC5134834.
View in:
PubMed Mentions:
31 Fields:
Translation:
Humans
-
Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. J Clin Oncol. 2015 Sep 20; 33(27):3018-28.
Olson TA, Murray MJ, Rodriguez-Galindo C, Nicholson JC, Billmire DF, Krailo MD, Dang HM, Amatruda JF, Thornton CM, Arul GS, Stoneham SJ, Pashankar F, Stark D, Shaikh F, Gershenson DM, Covens A, Hurteau J, Stenning SP, Feldman DR, Grimison PS, Huddart RA, Sweeney C, Powles T, Lopes LF, dos Santos Agular S, Chinnaswamy G, Khaleel S, Abouelnaga S, Hale JP, Frazier AL. PMID: 26304902; PMCID: PMC4979195.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Surveillance after initial surgery for Stage I pediatric and adolescent boys with malignant testicular germ cell tumors: Report from the Children's Oncology Group. J Pediatr Surg. 2015 Jun; 50(6):1000-3.
Rescorla FJ, Ross JH, Billmire DF, Dicken BJ, Villaluna D, Davis MM, Krailo M, Cullen JW, Olson TA, Egler RA, Amatruda JF, Rodrigues-Galindo C, Frazier AL. PMID: 25812445.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. J Clin Oncol. 2015 Jan 10; 33(2):195-201.
Frazier AL, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray MJ, Amatruda JF, Thornton C, Arul GS, Billmire D, Shaikh F, Pashankar F, Stoneham S, Krailo M, Nicholson JC. PMID: 25452439; PMCID: PMC4279239.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
-
Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nat Commun. 2014 Sep 05; 2:4802.
Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. PMID: 25190313; PMCID: PMC4159681.
View in:
PubMed Mentions:
117 Fields:
Translation:
HumansCells
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PAX7 expression defines germline stem cells in the adult testis. J Clin Invest. 2014 Sep; 124(9):3929-44.
Aloisio GM, Nakada Y, Saatcioglu HD, Peña CG, Baker MD, Tarnawa ED, Mukherjee J, Manjunath H, Bugde A, Sengupta AL, Amatruda JF, Cuevas I, Hamra FK, Castrillon DH. PMID: 25133429; PMCID: PMC4153705.
View in:
PubMed Mentions:
77 Fields:
Translation:
AnimalsCells
-
Spotlight on zebrafish: translational impact. Dis Model Mech. 2014 Jul; 7(7):731-3.
Patton EE, Dhillon P, Amatruda JF, Ramakrishnan L. PMID: 24973741; PMCID: PMC4073261.
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PubMed Mentions:
10 Fields:
Translation:
Animals
-
Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors. Oncologist. 2014 Jul; 19(7):689-92.
Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, Nicholson JC, Gershenson D, Frazier AL. PMID: 24899644; PMCID: PMC4077446.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell. 2014 Apr 24; 157(3):565-79.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. PMID: 24766806; PMCID: PMC4104514.
View in:
PubMed Mentions:
419 Fields:
Translation:
AnimalsCells
-
Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 2014 Apr; 10(4):572-87.
Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF. PMID: 24441423; PMCID: PMC4091146.
View in:
PubMed Mentions:
64 Fields:
Translation:
Animals
-
DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors. BMC Cancer. 2013 Jun 27; 13:313.
Amatruda JF, Ross JA, Christensen B, Fustino NJ, Chen KS, Hooten AJ, Nelson H, Kuriger JK, Rakheja D, Frazier AL, Poynter JN. PMID: 23806198; PMCID: PMC3701494.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
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A big catch for germ cell tumour research. PLoS Genet. 2013 Apr; 9(4):e1003481.
Chen KS, Amatruda JF. PMID: 23593043; PMCID: PMC3623754.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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The development of highly potent inhibitors for porcupine. J Med Chem. 2013 Mar 28; 56(6):2700-4.
Wang X, Moon J, Dodge ME, Pan X, Zhang L, Hanson JM, Tuladhar R, Ma Z, Shi H, Williams NS, Amatruda JF, Carroll TJ, Lum L, Chen C. PMID: 23477365; PMCID: PMC3631274.
View in:
PubMed Mentions:
48 Fields:
-
Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatr Blood Cancer. 2013 Jun; 60(6):1016-21.
Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G, COG Rare Tumors Disease Committee. PMID: 23255219; PMCID: PMC4304764.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
C/EBP transcription factors mediate epicardial activation during heart development and injury. Science. 2012 Dec 21; 338(6114):1599-603.
Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN. PMID: 23160954; PMCID: PMC3613149.
View in:
PubMed Mentions:
126 Fields:
Translation:
AnimalsCells
-
Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development. Mol Cancer Res. 2012 Nov; 10(11):1451-61.
Verduzco D, Dovey JS, Shukla AA, Kodym E, Skaug BA, Amatruda JF. PMID: 22986406; PMCID: PMC3511848.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Fetal and neonatal germ cell tumors. Semin Fetal Neonatal Med. 2012 Aug; 17(4):222-230.
Frazier AL, Weldon C, Amatruda J. PMID: 22647545.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. J Biol Chem. 2012 Jun 29; 287(27):23246-54.
Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, Lum L. PMID: 22593577; PMCID: PMC3391103.
View in:
PubMed Mentions:
37 Fields:
Translation:
HumansAnimalsCells
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In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains. Dev Biol. 2012 Jun 15; 366(2):327-40.
Moro E, Ozhan-Kizil G, Mongera A, Beis D, Wierzbicki C, Young RM, Bournele D, Domenichini A, Valdivia LE, Lum L, Chen C, Amatruda JF, Tiso N, Weidinger G, Argenton F. PMID: 22546689.
View in:
PubMed Mentions:
133 Fields:
Translation:
AnimalsCells
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Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms. Dis Model Mech. 2012 Jan; 5(1):33-7.
Hajeri VA, Amatruda JF. PMID: 22107871; PMCID: PMC3255541.
View in:
PubMed Mentions:
4 Fields:
Translation:
Animals
-
A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Dis Model Mech. 2012 Jan; 5(1):95-106.
Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF. PMID: 21979944; PMCID: PMC3255547.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
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Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish. Proc Natl Acad Sci U S A. 2011 Aug 09; 108(32):13153-8.
Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga L, Margraf L, Rakheja D, Amatruda JF. PMID: 21775673; PMCID: PMC3156187.
View in:
PubMed Mentions:
36 Fields:
Translation:
HumansAnimalsCells
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Bone morphogenetic protein signalling activity distinguishes histological subsets of paediatric germ cell tumours. Int J Androl. 2011 Aug; 34(4 Pt 2):e218-33.
Fustino N, Rakheja D, Ateek CS, Neumann JC, Amatruda JF. PMID: 21696393; PMCID: PMC4129369.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
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High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis. Genes Chromosomes Cancer. 2011 Jun; 50(6):397-408.
Paulson V, Chandler G, Rakheja D, Galindo RL, Wilson K, Amatruda JF, Cameron S. PMID: 21412928.
View in:
PubMed Mentions:
60 Fields:
Translation:
Humans
-
Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling. Sci Signal. 2011 Jan 25; 4(157):ra4.
Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L. PMID: 21266715; PMCID: PMC3790583.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Analysis of cell proliferation, senescence, and cell death in zebrafish embryos. Methods Cell Biol. 2011; 101:19-38.
Verduzco D, Amatruda JF. PMID: 21550438; PMCID: PMC3870180.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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Zebrafish models of germ cell tumor. Methods Cell Biol. 2011; 105:3-24.
Neumann JC, Lillard K, Damoulis V, Amatruda JF. PMID: 21951524; PMCID: PMC3932324.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Breast cancer between faith and medicine: the Peres Maldonado ex-voto. Med Humanit. 2010 Dec; 36(2):112-4.
Pon L, Amatruda JF. PMID: 21393294.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Trends in incidence and survival of pediatric and adolescent patients with germ cell tumors in the United States, 1975 to 2006. Cancer. 2010 Oct 15; 116(20):4882-91.
Poynter JN, Amatruda JF, Ross JA. PMID: 20597129; PMCID: PMC3931133.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
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Effect of vascular cadherin knockdown on zebrafish vasculature during development. PLoS One. 2010 Jan 20; 5(1):e8807.
Mitchell IC, Brown TS, Terada LS, Amatruda JF, Nwariaku FE. PMID: 20098718; PMCID: PMC2808391.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Identification of a heritable model of testicular germ cell tumor in the zebrafish. Zebrafish. 2009 Dec; 6(4):319-27.
Neumann JC, Dovey JS, Chandler GL, Carbajal L, Amatruda JF. PMID: 20047465; PMCID: PMC2811880.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansAnimals
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p53 ancestry: gazing through an evolutionary lens. Nat Rev Cancer. 2009 10; 9(10):758-62.
Lu WJ, Amatruda JF, Abrams JM. PMID: 19776745.
View in:
PubMed Mentions:
69 Fields:
Translation:
HumansAnimals
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Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Mol Cell Biol. 2009 Nov; 29(21):5911-22.
Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, Murphy C, Radtke I, Downing JR, Fleming MD, MacConaill LE, Amatruda JF, Gutierrez A, Galinsky I, Stone RM, Ross EA, Pellman DS, Kanki JP, Look AT. PMID: 19704007; PMCID: PMC2772726.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg Med Chem Lett. 2009 Jul 15; 19(14):3825-7.
Lu J, Ma Z, Hsieh JC, Fan CW, Chen B, Longgood JC, Williams NS, Amatruda JF, Lum L, Chen C. PMID: 19410457; PMCID: PMC2709695.
View in:
PubMed Mentions:
54 Fields:
Translation:
AnimalsCells
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Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol. 2009 Feb; 5(2):100-7.
Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. PMID: 19125156; PMCID: PMC2628455.
View in:
PubMed Mentions:
698 Fields:
Translation:
HumansCells
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Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell. 2008 May 30; 133(5):864-77.
Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R, Pascual J, Imamura S, Kishi S, Amatruda JF, Kanki JP, Green DR, D'Andrea AA, Look AT. PMID: 18510930; PMCID: PMC2719897.
View in:
PubMed Mentions:
178 Fields:
Translation:
HumansAnimalsCells
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Genetic models of cancer in zebrafish. Int Rev Cell Mol Biol. 2008; 271:1-34.
Amatruda JF, Patton EE. PMID: 19081540.
View in:
PubMed Mentions:
44 Fields:
Translation:
HumansAnimals
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The INT6 cancer gene and MEK signaling pathways converge during zebrafish development. PLoS One. 2007 Sep 26; 2(9):e959.
Grzmil M, Whiting D, Maule J, Anastasaki C, Amatruda JF, Kelsh RN, Norbury CJ, Patton EE. PMID: 17895999; PMCID: PMC1978538.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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A mutation in separase causes genome instability and increased susceptibility to epithelial cancer. Genes Dev. 2007 Jan 01; 21(1):55-9.
Shepard JL, Amatruda JF, Finkelstein D, Ziai J, Finley KR, Stern HM, Chiang K, Hersey C, Barut B, Freeman JL, Lee C, Glickman JN, Kutok JL, Aster JC, Zon LI. PMID: 17210788; PMCID: PMC1759900.
View in:
PubMed Mentions:
42 Fields:
Translation:
AnimalsCells
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Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nat Chem Biol. 2005 Dec; 1(7):366-70.
Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. PMID: 16372403.
View in:
PubMed Mentions:
73 Fields:
Translation:
AnimalsCells
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A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13194-9.
Shepard JL, Amatruda JF, Stern HM, Subramanian A, Finkelstein D, Ziai J, Finley KR, Pfaff KL, Hersey C, Zhou Y, Barut B, Freedman M, Lee C, Spitsbergen J, Neuberg D, Weber G, Golub TR, Glickman JN, Kutok JL, Aster JC, Zon LI. PMID: 16150706; PMCID: PMC1198999.
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76 Fields:
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AnimalsCells
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BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma. Curr Biol. 2005 Feb 08; 15(3):249-54.
Patton EE, Widlund HR, Kutok JL, Kopani KR, Amatruda JF, Murphey RD, Berghmans S, Mayhall EA, Traver D, Fletcher CD, Aster JC, Granter SR, Look AT, Lee C, Fisher DE, Zon LI. PMID: 15694309.
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265 Fields:
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AnimalsCells
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Analysis of the cell cycle in zebrafish embryos. Methods Cell Biol. 2004; 76:109-25.
Shepard JL, Stern HM, Pfaff KL, Amatruda JF. PMID: 15602874.
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27 Fields:
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AnimalsCells
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Zebrafish as a cancer model system. Cancer Cell. 2002 Apr; 1(3):229-31.
Amatruda JF, Shepard JL, Stern HM, Zon LI. PMID: 12086858.
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111 Fields:
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Animals
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Dissecting hematopoiesis and disease using the zebrafish. Dev Biol. 1999 Dec 01; 216(1):1-15.
Amatruda JF, Zon LI. PMID: 10588859.
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31 Fields:
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HumansAnimalsCells
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Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity. Mol Pharmacol. 1999 Dec; 56(6):1105-15.
Fiorani P, Amatruda JF, Silvestri A, Butler RH, Bjornsti MA, Benedetti P. PMID: 10570037.
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PubMed Mentions:
22 Fields:
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HumansAnimalsCells
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Diagnosis in oncology. Askin tumor. J Clin Oncol. 1998 May; 16(5):1997-8.
Amatruda JF, Tran K, Mantel M, Singer S, Demetri G. PMID: 9586920.
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PubMed Mentions:
1 Fields:
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Humans
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Effects of null mutations and overexpression of capping protein on morphogenesis, actin distribution and polarized secretion in yeast. J Cell Biol. 1992 Dec; 119(5):1151-62.
Amatruda JF, Gattermeir DJ, Karpova TS, Cooper JA. PMID: 1447293; PMCID: PMC2289735.
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PubMed Mentions:
70 Fields:
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AnimalsCells
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Purification, characterization, and immunofluorescence localization of Saccharomyces cerevisiae capping protein. J Cell Biol. 1992 Jun; 117(5):1067-76.
Amatruda JF, Cooper JA. PMID: 1315784; PMCID: PMC2289475.
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62 Fields:
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Animals
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Variant cDNAs encoding proteins similar to the alpha subunit of chicken CapZ. Cell Motil Cytoskeleton. 1991; 18(3):204-14.
Cooper JA, Caldwell JE, Gattermeir DJ, Torres MA, Amatruda JF, Casella JF. PMID: 1711931.
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PubMed Mentions:
12 Fields:
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AnimalsCells
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Disruption of the actin cytoskeleton in yeast capping protein mutants. Nature. 1990 Mar 22; 344(6264):352-4.
Amatruda JF, Cannon JF, Tatchell K, Hug C, Cooper JA. PMID: 2179733.
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82 Fields:
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AnimalsCells
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A high yield purification of the human transferrin receptor and properties of its major extracellular fragment. J Biol Chem. 1988 Jun 15; 263(17):8318-25.
Turkewitz AP, Amatruda JF, Borhani D, Harrison SC, Schwartz AL. PMID: 3372526.
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19 Fields:
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HumansCells