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Clinicopathologic predictors of outcomes in children with stage I testicular germ cell tumors: A pooled post hoc analysis of trials from the Children's Oncology Group. J Pediatr Urol. 2022 May 07.
Singla N, Wong J, Singla S, Krailo M, Huang L, Shaikh F, Billmire D, Rescorla F, Ross J, Dicken B, Amatruda JF, Lindsay Frazier A, Bagrodia A. PMID: 35606324.
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PubMed Mentions:
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Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth. Elife. 2022 03 14; 11.
Vasileva E, Warren M, Triche TJ, Amatruda JF. PMID: 35285802; PMCID: PMC8942468.
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Pitfalls in the diagnosis of yolk sac tumor: Lessons from a clinical trial. Pediatr Blood Cancer. 2022 02; 69(2):e29451.
Yang A, Patterson A, Pavlock T, Chen KS, Gagan J, Hatley ME, Frazier AL, Amatruda JF, Laetsch TW, Rakheja D. PMID: 34866303.
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PubMed Mentions:
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A Multi-institutional Pooled Analysis Demonstrates That Circulating miR-371a-3p Alone is Sufficient for Testicular Malignant Germ Cell Tumor Diagnosis. Clin Genitourin Cancer. 2021 12; 19(6):469-479.
Piao J, Lafin JT, Scarpini CG, Nuño MM, Syring I, Dieckmann KP, Belge G, Ellinger J, Amatruda JF, Bagrodia A, Coleman N, Krailo MD, Frazier AL, Murray MJ. PMID: 34629299.
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PubMed Mentions: Fields:
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The developmental origin of cancers defines basic principles of cisplatin resistance. Cancer Lett. 2021 10 28; 519:199-210.
Skowron MA, Oing C, Bremmer F, Ströbel P, Murray MJ, Coleman N, Amatruda JF, Honecker F, Bokemeyer C, Albers P, Nettersheim D. PMID: 34320371.
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PubMed Mentions: Fields:
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The Road Ahead for Circulating microRNAs in Diagnosis and Management of Testicular Germ Cell Tumors. Mol Diagn Ther. 2021 05; 25(3):269-271.
Lafin JT, Murray MJ, Coleman N, Frazier AL, Amatruda JF, Bagrodia A. PMID: 33893623.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Prioritization of Novel Agents for Patients with Rhabdomyosarcoma: A Report from the Children's Oncology Group (COG) New Agents for Rhabdomyosarcoma Task Force. J Clin Med. 2021 Apr 01; 10(7).
Pacenta HL, Allen-Rhoades W, Langenau D, Houghton PJ, Keller C, Heske CM, Deel MD, Linardic CM, Shern JF, Stewart E, Turpin B, Harrison DJ, Khan J, Mascarenhas L, Skapek SX, Meyer WH, Hawkins DS, Chen EY, Amatruda JF, Hingorani P, Laetsch TW. PMID: 33915882; PMCID: PMC8037615.
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PubMed Mentions:
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RAD21 is a driver of chromosome 8 gain in Ewing sarcoma to mitigate replication stress. Genes Dev. 2021 04 01; 35(7-8):556-572.
Su XA, Ma D, Parsons JV, Replogle JM, Amatruda JF, Whittaker CA, Stegmaier K, Amon A. PMID: 33766983; PMCID: PMC8015718.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Serum Small RNA Sequencing and miR-375 Assay Do Not Identify the Presence of Pure Teratoma at Postchemotherapy Retroperitoneal Lymph Node Dissection. Eur Urol Open Sci. 2021 Apr; 26:83-87.
Lafin JT, Kenigsberg AP, Meng X, Abe D, Savelyeva A, Singla N, Woldu SL, Lotan Y, Mauck RJ, Lewis CM, Margulis V, Wong D, Jia L, Kapur P, Xu L, Speir RW, Chesnut GT, Frazier AL, Strand DW, Coleman N, Murray MJ, Amatruda JF, Bagrodia A. PMID: 33997822; PMCID: PMC8121258.
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PubMed Mentions:
3
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Neonatal Malignant Disorders: Germ Cell Tumors. Clin Perinatol. 2021 03; 48(1):147-165.
Shah R, Weil BR, Weldon CB, Amatruda JF, Frazier AL. PMID: 33583501.
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PubMed Mentions: Fields:
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Modeling the developmental origins of pediatric cancer to improve patient outcomes. Dis Model Mech. 2021 02 22; 14(2).
Amatruda JF. PMID: 33619212; PMCID: PMC7927656.
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PubMed Mentions:
1 Fields:
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Germ Cell Tumor Cell Culture Techniques. Methods Mol Biol. 2021; 2195:65-76.
Lafin JT, Amatruda JF, Bagrodia A. PMID: 32852757.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Developing and Using a Data Commons for Understanding the Molecular Characteristics of Germ Cell Tumors. Methods Mol Biol. 2021; 2195:263-275.
Ci B, Lin SY, Yao B, Luo D, Xu L, Krailo M, Murray MJ, Amatruda JF, Frazier AL, Xie Y. PMID: 32852769.
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PubMed Mentions: Fields:
Translation:
Humans
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Correction to: Germ Cell Tumor Cell Culture Techniques. Methods Mol Biol. 2021; 2195:C1.
Lafin JT, Amatruda JF, Bagrodia A. PMID: 34453282.
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PubMed Mentions: Fields:
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Impact of circulating microRNA test (miRNA-371a-3p) on appropriateness of treatment and cost outcomes in patients with Stage I non-seminomatous germ cell tumours. BJU Int. 2021 07; 128(1):57-64.
Bagrodia A, Savelyeva A, Lafin JT, Speir RW, Chesnut GT, Frazier AL, Woldu SL, Margulis V, Murray MJ, Amatruda JF, Lotan Y. PMID: 33124175.
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PubMed Mentions:
1 Fields:
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Outcomes of adolescent males with extracranial metastatic germ cell tumors: A report from the Malignant Germ Cell Tumor International Consortium. Cancer. 2021 01 15; 127(2):193-202.
Shaikh F, Stark D, Fonseca A, Dang H, Xia C, Krailo M, Pashankar F, Rodriguez-Galindo C, Olson TA, Nicholson JC, Murray MJ, Amatruda JF, Billmire D, Stoneham S, Frazier AL. PMID: 33079404.
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PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
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Real-World Application of Pre-Orchiectomy miR-371a-3p Test in Testicular Germ Cell Tumor Management. J Urol. 2021 Jan; 205(1):137-144.
Badia RR, Abe D, Wong D, Singla N, Savelyeva A, Chertack N, Woldu SL, Lotan Y, Mauck R, Ouyang D, Meng X, Lewis CM, Majmudar K, Jia L, Kapur P, Xu L, Frazier AL, Margulis V, Strand DW, Coleman N, Murray MJ, Amatruda JF, Lafin JT, Bagrodia A. PMID: 32856980.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Development of a Data Model and Data Commons for Germ Cell Tumors. JCO Clin Cancer Inform. 2020 06; 4:555-566.
Ci B, Yang DM, Krailo M, Xia C, Yao B, Luo D, Zhou Q, Xiao G, Xu L, Skapek SX, Murray MM, Amatruda JF, Klosterkemper L, Shaikh F, Faure-Conter C, Fresneau B, Volchenboum SL, Stoneham S, Lopes LF, Nicholson J, Frazier AL, Xie Y. PMID: 32568554; PMCID: PMC7328105.
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PubMed Mentions: Fields:
Translation:
Humans
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Birth Characteristics and Risk of Early-Onset Synovial Sarcoma. Cancer Epidemiol Biomarkers Prev. 2020 06; 29(6):1162-1167.
Wiemels JL, Wiemels JL, Wang R, Feng Q, Clark CJ, Amatruda JF, Rubin E, Yee AC, Morimoto LM, Metayer C, Ma X. PMID: 32245786; PMCID: PMC7605594.
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PubMed Mentions: Fields:
Translation:
Humans
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GCNA Preserves Genome Integrity and Fertility Across Species. Dev Cell. 2020 01 06; 52(1):38-52.e10.
Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, Yanowitz JL, Buszczak M. PMID: 31839537; PMCID: PMC6946843.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Serum MicroRNA-371a-3p Levels Predict Viable Germ Cell Tumor in Chemotherapy-naïve Patients Undergoing Retroperitoneal Lymph Node Dissection. Eur Urol. 2020 02; 77(2):290-292.
Lafin JT, Singla N, Woldu SL, Lotan Y, Lewis CM, Majmudar K, Savelyeva A, Kapur P, Margulis V, Strand DW, Murray MJ, Amatruda JF, Bagrodia A. PMID: 31699528; PMCID: PMC7756387.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Genetics of testicular germ cell tumors. Curr Opin Urol. 2019 07; 29(4):344-349.
Singla N, Lafin JT, Ghandour RA, Kaffenberger S, Amatruda JF, Bagrodia A. PMID: 31045925; PMCID: PMC6659740.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Detection of Relapse by Tumor Markers Versus Imaging in Children and Adolescents With Nongerminomatous Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2019 02 10; 37(5):396-402.
Fonseca A, Xia C, Lorenzo AJ, Krailo M, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Billmire DF, Rodriguez-Galindo C, Frazier AL, Shaikh F. PMID: 30576269; PMCID: PMC6553816.
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PubMed Mentions: Fields:
Translation:
Humans
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pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish. Dev Dyn. 2019 02; 248(2):173-188.
Bhakta M, Padanad MS, Harris JP, Lubczyk C, Amatruda JF, Munshi NV. PMID: 30444277; PMCID: PMC6340724.
View in:
PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 10; 119(7):864-872.
Williams LA, Mills L, Hooten AJ, Langer E, Roesler M, Frazier AL, Krailo M, Nelson HH, Bestrashniy J, Amatruda JF, Poynter JN. PMID: 30287918; PMCID: PMC6189207.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Klinefelter syndrome in males with germ cell tumors: A report from the Children's Oncology Group. Cancer. 2018 10 01; 124(19):3900-3908.
Williams LA, Pankratz N, Lane J, Krailo M, Roesler M, Richardson M, Frazier AL, Amatruda JF, Poynter JN. PMID: 30291793; PMCID: PMC6241518.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Mutations in microRNA processing genes in Wilms tumors derepress the IGF2 regulator PLAG1. Genes Dev. 2018 08 01; 32(15-16):996-1007.
Chen KS, Stroup EK, Budhipramono A, Rakheja D, Nichols-Vinueza D, Xu L, Stuart SH, Shukla AA, Fraire C, Mendell JT, Amatruda JF. PMID: 30026293; PMCID: PMC6075147.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes. Cell Rep. 2018 07 03; 24(1):238-251.
Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX. PMID: 29972784; PMCID: PMC7293769.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Practice Patterns and Impact of Postchemotherapy Retroperitoneal Lymph Node Dissection on Testicular Cancer Outcomes. Eur Urol Oncol. 2018 08; 1(3):242-251.
Woldu SL, Moore JA, Ci B, Freifeld Y, Clinton TN, Aydin AM, Singla N, Laura-Maria K, Hutchinson RC, Amatruda JF, Sagalowsky A, Lotan Y, Arriaga Y, Margulis V, Xie Y, Bagrodia A. PMID: 31058267; PMCID: PMC6494089.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Is carboplatin-based chemotherapy as effective as cisplatin-based chemotherapy in the treatment of advanced-stage dysgerminoma in children, adolescents and young adults? Gynecol Oncol. 2018 08; 150(2):253-260.
Shah R, Xia C, Krailo M, Amatruda JF, Arul SG, Billmire DF, Brady WE, Covens A, Gershenson DM, Hale JP, Hurteau J, Murray MJ, Nicholson JC, Olson TA, Pashankar F, Rodriguez-Galindo C, Shaikh F, Stark D, Frazier AL, Stoneham S. PMID: 29884437.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. Elife. 2018 06 05; 7.
Kendall GC, Watson S, Xu L, LaVigne CA, Murchison W, Rakheja D, Skapek SX, Tirode F, Delattre O, Amatruda JF. PMID: 29869612; PMCID: PMC5988421.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Comparison of carboplatin versus cisplatin in the treatment of paediatric extracranial malignant germ cell tumours: A report of the Malignant Germ Cell International Consortium. Eur J Cancer. 2018 07; 98:30-37.
Frazier AL, Stoneham S, Rodriguez-Galindo C, Dang H, Xia C, Olson TA, Murray MJ, Amatruda JF, Shaikh F, Pashankar F, Billmire D, Krailo M, Stark D, Brougham MFH, Nicholson JC, Hale JP. PMID: 29859339.
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PubMed Mentions:
4 Fields:
Translation:
Humans
-
EGF Receptor and mTORC1 Are Novel Therapeutic Targets in Nonseminomatous Germ Cell Tumors. Mol Cancer Ther. 2018 05; 17(5):1079-1089.
Chen KS, Fustino NJ, Shukla AA, Stroup EK, Budhipramono A, Ateek C, Stuart SH, Yamaguchi K, Kapur P, Frazier AL, Lum L, Looijenga LHJ, Laetsch TW, Rakheja D, Amatruda JF. PMID: 29483210; PMCID: PMC5932259.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Pediatric Germ Cell Tumors: A Developmental Perspective. Adv Urol. 2018; 2018:9059382.
Pierce JL, Frazier AL, Amatruda JF. PMID: 29515628; PMCID: PMC5817207.
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PubMed Mentions:
15
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Adolescents and Young Adults With a "Rare" Cancer: Getting Past Semantics to Optimal Care for Patients With Germ Cell Tumors. Oncologist. 2018 02; 23(2):272.
Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, Nicholson JC, Gershenson D, Frazier AL. PMID: 29449513; PMCID: PMC5813761.
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PubMed Mentions: Fields:
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Gonadal dysgenesis is associated with worse outcomes in patients with ovarian nondysgerminomatous tumors: A report of the Children's Oncology Group AGCT 0132 study. Pediatr Blood Cancer. 2018 04; 65(4).
Dicken BJ, Billmire DF, Krailo M, Xia C, Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Rescorla FJ, Egler RA, Ross JH, Rodriguez-Galindo C, Frazier AL. PMID: 29286555; PMCID: PMC6219870.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Differences at Presentation and Treatment of Testicular Cancer in Hispanic Men: Institutional and National Hospital-based Analyses. Urology. 2018 02; 112:103-111.
Woldu SL, Aydin AM, Rao AV, Hutchinson RC, Singla N, Clinton TN, Krabbe LM, Passoni NM, Raj GV, Miller DS, Amatruda JF, Sagalowsky AI, Lotan Y, Arriaga Y, Margulis V, Bagrodia A. PMID: 29079210.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Family history of cancer in children and adolescents with germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 01; 118(1):121-126.
Poynter JN, Richardson M, Roesler M, Krailo M, Amatruda JF, Frazier AL. PMID: 29065103; PMCID: PMC5765220.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Retrotransposons Mimic Germ Plasm Determinants to Promote Transgenerational Inheritance. Curr Biol. 2017 Oct 09; 27(19):3010-3016.e3.
Tiwari B, Kurtz P, Jones AE, Wylie A, Amatruda JF, Boggupalli DP, Gonsalvez GB, Abrams JM. PMID: 28966088; PMCID: PMC5639916.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Variants in BAK1, SPRY4, and GAB2 are associated with pediatric germ cell tumors: A report from the children's oncology group. Genes Chromosomes Cancer. 2017 07; 56(7):548-558.
Marcotte EL, Pankratz N, Amatruda JF, Frazier AL, Krailo M, Davies S, Starr JR, Lau CC, Roesler M, Langer E, Hallstrom C, Hooten AJ, Poynter JN. PMID: 28295819; PMCID: PMC5612339.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children's Oncology Group. J Clin Oncol. 2017 Apr 10; 35(11):1203-1210.
Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Villaluna D, Krailo M, Billmire DF, Rescorla FJ, Egler RA, Dicken BJ, Ross JH, Schlatter M, Rodriguez-Galindo C, Frazier AL. PMID: 28240974; PMCID: PMC5455599.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCTClinical Trials
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Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):1649-1654.
Moon J, Zhou H, Zhang LS, Tan W, Liu Y, Zhang S, Morlock LK, Bao X, Palecek SP, Feng JQ, Williams NS, Amatruda JF, Olson EN, Bassel-Duby R, Lum L. PMID: 28143939; PMCID: PMC5320972.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Testicular germ cell tumor genomics. Curr Opin Urol. 2017 01; 27(1):41-47.
Woldu SL, Amatruda JF, Bagrodia A. PMID: 27584029; PMCID: PMC6368344.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation. Nat Med. 2017 01; 23(1):79-90.
Lu Z, Xie J, Wu G, Shen J, Collins R, Chen W, Kang X, Luo M, Zou Y, Huang LJ, Amatruda JF, Slone T, Winick N, Scherer PE, Zhang CC. PMID: 27941793; PMCID: PMC6956990.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Genetic inhibition of autophagy promotes p53 loss-of-heterozygosity and tumorigenesis. Oncotarget. 2016 10 18; 7(42):67919-67933.
Lee E, Wei Y, Zou Z, Tucker K, Rakheja D, Levine B, Amatruda JF. PMID: 27655644; PMCID: PMC5356529.
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PubMed Mentions:
7 Fields:
Translation:
Animals
-
Risk of second gonadal cancers in women and children with germ cell tumors. Cancer. 2016 07 01; 122(13):2076-82.
Liao ZW, Rodrigues MC, Poynter JN, Amatruda JF, Rodriguez-Galindo C, Frazier AL. PMID: 27152727.
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PubMed Mentions: Fields:
Translation:
Humans
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Paediatric extracranial germ-cell tumours. Lancet Oncol. 2016 04; 17(4):e149-e162.
Shaikh F, Murray MJ, Amatruda JF, Coleman N, Nicholson JC, Hale JP, Pashankar F, Stoneham SJ, Poynter JN, Olson TA, Billmire DF, Stark D, Rodriguez-Galindo C, Frazier AL. PMID: 27300675.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Zebrafish as a Model for the Study of Solid Malignancies. Methods Mol Biol. 2016; 1451:121-42.
Kendall GC, Amatruda JF. PMID: 27464805.
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PubMed Mentions:
2 Fields:
Translation:
Animals
-
Zebrafish Germ Cell Tumors. Adv Exp Med Biol. 2016; 916:479-94.
Sanchez A, Amatruda JF. PMID: 27165367; PMCID: PMC4959914.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimals
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Biochemical Analysis of Tankyrase Activity in Zebrafish In Vitro and In Vivo. Methods Mol Biol. 2016; 1481:95-100.
Moon J, Amatruda JF. PMID: 27590155.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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p53 genes function to restrain mobile elements. Genes Dev. 2016 Jan 01; 30(1):64-77.
Wylie A, Jones AE, D'Brot A, Lu WJ, Kurtz P, Moran JV, Rakheja D, Chen KS, Hammer RE, Comerford SA, Amatruda JF, Abrams JM. PMID: 26701264; PMCID: PMC4701979.
View in:
PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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Is adjuvant chemotherapy indicated in ovarian immature teratomas? A combined data analysis from the Malignant Germ Cell Tumor International Collaborative. Cancer. 2016 Jan 15; 122(2):230-7.
Pashankar F, Hale JP, Dang H, Krailo M, Brady WE, Rodriguez-Galindo C, Nicholson JC, Murray MJ, Bilmire DF, Stoneham S, Arul GS, Olson TA, Stark D, Shaikh F, Amatruda JF, Covens A, Gershenson DM, Frazier AL. PMID: 26485622; PMCID: PMC5134834.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. J Clin Oncol. 2015 Sep 20; 33(27):3018-28.
Olson TA, Murray MJ, Rodriguez-Galindo C, Nicholson JC, Billmire DF, Krailo MD, Dang HM, Amatruda JF, Thornton CM, Arul GS, Stoneham SJ, Pashankar F, Stark D, Shaikh F, Gershenson DM, Covens A, Hurteau J, Stenning SP, Feldman DR, Grimison PS, Huddart RA, Sweeney C, Powles T, Lopes LF, dos Santos Agular S, Chinnaswamy G, Khaleel S, Abouelnaga S, Hale JP, Frazier AL. PMID: 26304902; PMCID: PMC4979195.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Surveillance after initial surgery for Stage I pediatric and adolescent boys with malignant testicular germ cell tumors: Report from the Children's Oncology Group. J Pediatr Surg. 2015 Jun; 50(6):1000-3.
Rescorla FJ, Ross JH, Billmire DF, Dicken BJ, Villaluna D, Davis MM, Krailo M, Cullen JW, Olson TA, Egler RA, Amatruda JF, Rodrigues-Galindo C, Frazier AL. PMID: 25812445.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
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Revised risk classification for pediatric extracranial germ cell tumors based on 25 years of clinical trial data from the United Kingdom and United States. J Clin Oncol. 2015 Jan 10; 33(2):195-201.
Frazier AL, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray MJ, Amatruda JF, Thornton C, Arul GS, Billmire D, Shaikh F, Pashankar F, Stoneham S, Krailo M, Nicholson JC. PMID: 25452439; PMCID: PMC4279239.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
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Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours. Nat Commun. 2014 Sep 05; 2:4802.
Rakheja D, Chen KS, Liu Y, Shukla AA, Schmid V, Chang TC, Khokhar S, Wickiser JE, Karandikar NJ, Malter JS, Mendell JT, Amatruda JF. PMID: 25190313; PMCID: PMC4159681.
View in:
PubMed Mentions:
78 Fields:
Translation:
HumansCells
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Spotlight on zebrafish: translational impact. Dis Model Mech. 2014 Jul; 7(7):731-3.
Patton EE, Dhillon P, Amatruda JF, Ramakrishnan L. PMID: 24973741; PMCID: PMC4073261.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Adolescents and young adults with a "rare" cancer: getting past semantics to optimal care for patients with germ cell tumors. Oncologist. 2014 Jul; 19(7):689-92.
Stoneham SJ, Hale JP, Rodriguez-Galindo C, Dang H, Olson T, Murray M, Amatruda JF, Thornton C, Arul GS, Billmire D, Krailo M, Stark D, Covens A, Hurteau J, Stenning S, Nicholson JC, Gershenson D, Frazier AL. PMID: 24899644; PMCID: PMC4077446.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
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The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response. Cell. 2014 Apr 24; 157(3):565-79.
Puente BN, Kimura W, Muralidhar SA, Moon J, Amatruda JF, Phelps KL, Grinsfelder D, Rothermel BA, Chen R, Garcia JA, Santos CX, Thet S, Mori E, Kinter MT, Rindler PM, Zacchigna S, Mukherjee S, Chen DJ, Mahmoud AI, Giacca M, Rabinovitch PS, Aroumougame A, Shah AM, Szweda LI, Sadek HA. PMID: 24766806; PMCID: PMC4104514.
View in:
PubMed Mentions:
248 Fields:
Translation:
AnimalsCells
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Autophagy is essential for cardiac morphogenesis during vertebrate development. Autophagy. 2014 Apr; 10(4):572-87.
Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF. PMID: 24441423; PMCID: PMC4091146.
View in:
PubMed Mentions:
48 Fields:
Translation:
Animals
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DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors. BMC Cancer. 2013 Jun 27; 13:313.
Amatruda JF, Ross JA, Christensen B, Fustino NJ, Chen KS, Hooten AJ, Nelson H, Kuriger JK, Rakheja D, Frazier AL, Poynter JN. PMID: 23806198; PMCID: PMC3701494.
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16 Fields:
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HumansCells
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A big catch for germ cell tumour research. PLoS Genet. 2013 Apr; 9(4):e1003481.
Chen KS, Amatruda JF. PMID: 23593043; PMCID: PMC3623754.
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1 Fields:
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HumansAnimals
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The development of highly potent inhibitors for porcupine. J Med Chem. 2013 Mar 28; 56(6):2700-4.
Wang X, Moon J, Dodge ME, Pan X, Zhang L, Hanson JM, Tuladhar R, Ma Z, Shi H, Williams NS, Amatruda JF, Carroll TJ, Lum L, Chen C. PMID: 23477365; PMCID: PMC3631274.
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PubMed Mentions:
35 Fields:
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Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatr Blood Cancer. 2013 Jun; 60(6):1016-21.
Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G, COG Rare Tumors Disease Committee. PMID: 23255219; PMCID: PMC4304764.
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10 Fields:
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Humans
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C/EBP transcription factors mediate epicardial activation during heart development and injury. Science. 2012 Dec 21; 338(6114):1599-603.
Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN. PMID: 23160954; PMCID: PMC3613149.
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PubMed Mentions:
90 Fields:
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AnimalsCells
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Multiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development. Mol Cancer Res. 2012 Nov; 10(11):1451-61.
Verduzco D, Dovey JS, Shukla AA, Kodym E, Skaug BA, Amatruda JF. PMID: 22986406; PMCID: PMC3511848.
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PubMed Mentions:
5 Fields:
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HumansAnimalsCells
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Fetal and neonatal germ cell tumors. Semin Fetal Neonatal Med. 2012 Aug; 17(4):222-230.
Frazier AL, Weldon C, Amatruda J. PMID: 22647545.
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4 Fields:
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Humans
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Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine. J Biol Chem. 2012 Jun 29; 287(27):23246-54.
Dodge ME, Moon J, Tuladhar R, Lu J, Jacob LS, Zhang LS, Shi H, Wang X, Moro E, Mongera A, Argenton F, Karner CM, Carroll TJ, Chen C, Amatruda JF, Lum L. PMID: 22593577; PMCID: PMC3391103.
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PubMed Mentions:
32 Fields:
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HumansAnimalsCells
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Studying synthetic lethal interactions in the zebrafish system: insight into disease genes and mechanisms. Dis Model Mech. 2012 Jan; 5(1):33-7.
Hajeri VA, Amatruda JF. PMID: 22107871; PMCID: PMC3255541.
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PubMed Mentions:
3 Fields:
Translation:
Animals
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A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis. Dis Model Mech. 2012 Jan; 5(1):95-106.
Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF. PMID: 21979944; PMCID: PMC3255547.
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PubMed Mentions:
25 Fields:
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HumansAnimals
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Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish. Proc Natl Acad Sci U S A. 2011 Aug 09; 108(32):13153-8.
Neumann JC, Chandler GL, Damoulis VA, Fustino NJ, Lillard K, Looijenga L, Margraf L, Rakheja D, Amatruda JF. PMID: 21775673; PMCID: PMC3156187.
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PubMed Mentions:
29 Fields:
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HumansAnimalsCells
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High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis. Genes Chromosomes Cancer. 2011 Jun; 50(6):397-408.
Paulson V, Chandler G, Rakheja D, Galindo RL, Wilson K, Amatruda JF, Cameron S. PMID: 21412928.
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PubMed Mentions:
53 Fields:
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Humans
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Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling. Sci Signal. 2011 Jan 25; 4(157):ra4.
Jacob LS, Wu X, Dodge ME, Fan CW, Kulak O, Chen B, Tang W, Wang B, Amatruda JF, Lum L. PMID: 21266715; PMCID: PMC3790583.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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Analysis of cell proliferation, senescence, and cell death in zebrafish embryos. Methods Cell Biol. 2011; 101:19-38.
Verduzco D, Amatruda JF. PMID: 21550438; PMCID: PMC3870180.
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PubMed Mentions:
19 Fields:
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HumansAnimals
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Zebrafish models of germ cell tumor. Methods Cell Biol. 2011; 105:3-24.
Neumann JC, Lillard K, Damoulis V, Amatruda JF. PMID: 21951524; PMCID: PMC3932324.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Breast cancer between faith and medicine: the Peres Maldonado ex-voto. Med Humanit. 2010 Dec; 36(2):112-4.
Pon L, Amatruda JF. PMID: 21393294.
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Humans
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Trends in incidence and survival of pediatric and adolescent patients with germ cell tumors in the United States, 1975 to 2006. Cancer. 2010 Oct 15; 116(20):4882-91.
Poynter JN, Amatruda JF, Ross JA. PMID: 20597129; PMCID: PMC3931133.
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PubMed Mentions:
26 Fields:
Translation:
Humans
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Effect of vascular cadherin knockdown on zebrafish vasculature during development. PLoS One. 2010 Jan 20; 5(1):e8807.
Mitchell IC, Brown TS, Terada LS, Amatruda JF, Nwariaku FE. PMID: 20098718; PMCID: PMC2808391.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Identification of a heritable model of testicular germ cell tumor in the zebrafish. Zebrafish. 2009 Dec; 6(4):319-27.
Neumann JC, Dovey JS, Chandler GL, Carbajal L, Amatruda JF. PMID: 20047465; PMCID: PMC2811880.
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PubMed Mentions:
21 Fields:
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HumansAnimals
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p53 ancestry: gazing through an evolutionary lens. Nat Rev Cancer. 2009 10; 9(10):758-62.
Lu WJ, Amatruda JF, Abrams JM. PMID: 19776745.
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PubMed Mentions:
57 Fields:
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HumansAnimals
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Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg Med Chem Lett. 2009 Jul 15; 19(14):3825-7.
Lu J, Ma Z, Hsieh JC, Fan CW, Chen B, Longgood JC, Williams NS, Amatruda JF, Lum L, Chen C. PMID: 19410457; PMCID: PMC2709695.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol. 2009 Feb; 5(2):100-7.
Chen B, Dodge ME, Tang W, Lu J, Ma Z, Fan CW, Wei S, Hao W, Kilgore J, Williams NS, Roth MG, Amatruda JF, Chen C, Lum L. PMID: 19125156; PMCID: PMC2628455.
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PubMed Mentions:
595 Fields:
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HumansCells
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Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3. Cell. 2008 May 30; 133(5):864-77.
Sidi S, Sanda T, Kennedy RD, Hagen AT, Jette CA, Hoffmans R, Pascual J, Imamura S, Kishi S, Amatruda JF, Kanki JP, Green DR, D'Andrea AA, Look AT. PMID: 18510930; PMCID: PMC2719897.
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PubMed Mentions:
159 Fields:
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HumansAnimalsCells
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Genetic models of cancer in zebrafish. Int Rev Cell Mol Biol. 2008; 271:1-34.
Amatruda JF, Patton EE. PMID: 19081540.
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PubMed Mentions:
39 Fields:
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HumansAnimals
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Analysis of the cell cycle in zebrafish embryos. Methods Cell Biol. 2004; 76:109-25.
Shepard JL, Stern HM, Pfaff KL, Amatruda JF. PMID: 15602874.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells