Brooke Erika Hjelm

Title(s)Assistant Professor of Clinical Translational Genomics
SchoolKeck School of Medicine of Usc
Address1500 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Common mitochondrial deletions in RNA-Seq: evaluation of bulk, single-cell, and spatial transcriptomic datasets. Commun Biol. 2024 Feb 17; 7(1):200. Omidsalar AA, McCullough CG, Xu L, Boedijono S, Gerke D, Webb MG, Manojlovic Z, Sequeira A, Lew MF, Santorelli M, Serrano GE, Beach TG, Limon A, Vawter MP, Hjelm BE. PMID: 38368460; PMCID: PMC10874445.
      View in: PubMed   Mentions: Translation:HumansCells
    2. Mutations in genes related to myocyte contraction and ventricular septum development in non-syndromic tetralogy of Fallot. Front Cardiovasc Med. 2023; 10:1249605. Harvey DC, Verma R, Sedaghat B, Hjelm BE, Morton SU, Seidman JG, Kumar SR. PMID: 37840956; PMCID: PMC10569225.
      View in: PubMed   Mentions:
    3. The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis. Invest Ophthalmol Vis Sci. 2023 04 03; 64(4):1. Singh Kakan S, Li X, Edman MC, Okamoto CT, Hjelm BE, Hamm-Alvarez SF. PMID: 37010857; PMCID: PMC10080918.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    4. The Foundational Data Initiative for Parkinson Disease: Enabling efficient translation from genetic maps to mechanism. Cell Genom. 2023 Mar 08; 3(3):100261. Bressan E, Reed X, Bansal V, Hutchins E, Cobb MM, Webb MG, Alsop E, Grenn FP, Illarionova A, Savytska N, Violich I, Broeer S, Fernandes N, Sivakumar R, Beilina A, Billingsley KJ, Berghausen J, Pantazis CB, Pitz V, Patel D, Daida K, Meechoovet B, Reiman R, Courtright-Lim A, Logemann A, Antone J, Barch M, Kitchen R, Li Y, Dalgard CL, American Genome Center, Rizzu P, Hernandez DG, Hjelm BE, Nalls M, Gibbs JR, Finkbeiner S, Cookson MR, Van Keuren-Jensen K, Craig DW, Singleton AB, Heutink P, Blauwendraat C. PMID: 36950378; PMCID: PMC10025424.
      View in: PubMed   Mentions: 8     Fields:    
    5. Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3' Breakpoints. Complex Psychiatry. 2023 Jan; 8(3-4):90-98. Hjelm BE, Ramiro C, Rollins BL, Omidsalar AA, Gerke DS, Das SC, Sequeira A, Morgan L, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. PMID: 36778651; PMCID: PMC9909249.
      View in: PubMed   Mentions:
    6. Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder. Transl Psychiatry. 2022 08 30; 12(1):353. Das SC, Hjelm BE, Rollins BL, Sequeira A, Morgan L, Omidsalar AA, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Bunney WE, Vawter MP. PMID: 36042222; PMCID: PMC9427957.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    7. Tear miRNAs Identified in a Murine Model of Sjögren's Syndrome as Potential Diagnostic Biomarkers and Indicators of Disease Mechanism. Front Immunol. 2022; 13:833254. Kakan SS, Edman MC, Yao A, Okamoto CT, Nguyen A, Hjelm BE, Hamm-Alvarez SF. PMID: 35309364; PMCID: PMC8931289.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    8. Functional impairment of cortical AMPA receptors in schizophrenia. Schizophr Res. 2022 11; 249:25-37. Zeppillo T, Schulmann A, Macciardi F, Hjelm BE, Föcking M, Sequeira PA, Guella I, Cotter D, Bunney WE, Limon A, Vawter MP. PMID: 32513544; PMCID: PMC7718399.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    9. Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders. Nucleic Acids Res. 2019 06 04; 47(10):e59. Hjelm BE, Rollins B, Morgan L, Sequeira A, Mamdani F, Pereira F, Damas J, Webb MG, Weber MD, Schatzberg AF, Barchas JD, Lee FS, Akil H, Watson SJ, Myers RM, Chao EC, Kimonis V, Thompson PM, Bunney WE, Vawter MP. PMID: 30869147; PMCID: PMC6547454.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    10. Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. Cell Stem Cell. 2018 05 03; 22(5):698-712.e9. Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D. PMID: 29681516; PMCID: PMC6398951.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    11. Mitochondrial Complex I Deficiency in Schizophrenia and Bipolar Disorder and Medication Influence. Mol Neuropsychiatry. 2018 Feb; 3(3):157-169. Rollins BL, Morgan L, Hjelm BE, Sequeira A, Schatzberg AF, Barchas JD, Lee FS, Myers RM, Watson SJ, Akil H, Potkin SG, Bunney WE, Vawter MP. PMID: 29594135; PMCID: PMC5836256.
      View in: PubMed   Mentions: 21  
    12. Targets of polyamine dysregulation in major depression and suicide: Activity-dependent feedback, excitability, and neurotransmission. Neurosci Biobehav Rev. 2016 Jul; 66:80-91. Limon A, Mamdani F, Hjelm BE, Vawter MP, Sequeira A. PMID: 27108532; PMCID: PMC5096383.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    13. Mifepristone-inducible transgene expression in neural progenitor cells in vitro and in vivo. Gene Ther. 2016 05; 23(5):424-37. Hjelm BE, Grunseich C, Gowing G, Avalos P, Tian J, Shelley BC, Mooney M, Narwani K, Shi Y, Svendsen CN, Wolfe JH, Fischbeck KH, Pierson TM. PMID: 26863047; PMCID: PMC4976764.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    14. Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia. Mol Neuropsychiatry. 2015 Dec; 1(4):201-19. Hjelm BE, Rollins B, Mamdani F, Lauterborn JC, Kirov G, Lynch G, Gall CM, Sequeira A, Vawter MP. PMID: 26550561; PMCID: PMC4635522.
      View in: PubMed   Mentions: 48  
    15. TLR7 and 9 agonists are highly effective mucosal adjuvants for norovirus virus-like particle vaccines. Hum Vaccin Immunother. 2014; 10(2):410-6. Hjelm BE, Kilbourne J, Herbst-Kralovetz MM. PMID: 24280723; PMCID: PMC4185889.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    16. In vitro-differentiated neural cell cultures progress towards donor-identical brain tissue. Hum Mol Genet. 2013 Sep 01; 22(17):3534-46. Hjelm BE, Salhia B, Kurdoglu A, Szelinger S, Reiman RA, Sue LI, Beach TG, Huentelman MJ, Craig DW. PMID: 23666530; PMCID: PMC3736871.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    17. Lack of norovirus replication and histo-blood group antigen expression in 3-dimensional intestinal epithelial cells. Emerg Infect Dis. 2013 Mar; 19(3):431-8. Herbst-Kralovetz MM, Radtke AL, Lay MK, Hjelm BE, Bolick AN, Sarker SS, Atmar RL, Kingsley DH, Arntzen CJ, Estes MK, Nickerson CA. PMID: 23622517; PMCID: PMC3647661.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    18. Induction of pluripotent stem cells from autopsy donor-derived somatic cells. Neurosci Lett. 2011 Sep 20; 502(3):219-24. Hjelm BE, Rosenberg JB, Szelinger S, Sue LI, Beach TG, Huentelman MJ, Craig DW. PMID: 21839145; PMCID: PMC3195418.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    19. An intranasally delivered Toll-like receptor 7 agonist elicits robust systemic and mucosal responses to Norwalk virus-like particles. Clin Vaccine Immunol. 2010 Dec; 17(12):1850-8. Velasquez LS, Hjelm BE, Arntzen CJ, Herbst-Kralovetz MM. PMID: 20962211; PMCID: PMC3008198.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    20. Development and characterization of a three-dimensional organotypic human vaginal epithelial cell model. Biol Reprod. 2010 Mar; 82(3):617-27. Hjelm BE, Berta AN, Nickerson CA, Arntzen CJ, Herbst-Kralovetz MM. PMID: 20007410; PMCID: PMC6366157.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    21. A DNA replicon system for rapid high-level production of virus-like particles in plants. Biotechnol Bioeng. 2009 Jul 01; 103(4):706-14. Huang Z, Chen Q, Hjelm B, Arntzen C, Mason H. PMID: 19309755; PMCID: PMC2704498.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    22. An efficient plant viral expression system generating orally immunogenic Norwalk virus-like particles. Vaccine. 2008 Mar 28; 26(15):1846-54. Santi L, Batchelor L, Huang Z, Hjelm B, Kilbourne J, Arntzen CJ, Chen Q, Mason HS. PMID: 18325641; PMCID: PMC2744496.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    23. Application of electron tomography to fungal ultrastructure studies. New Phytol. 2006; 172(2):208-20. Hohmann-Marriott MF, Uchida M, van de Meene AM, Garret M, Hjelm BE, Kokoori S, Roberson RW. PMID: 16995909.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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