Paul Seidler

Title(s)	Assistant Professor of Pharmacology and Pharmaceutical Sciences
Address	PSC 530 Health Sciences Campus Los Angeles CA 90089-9121
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Correction to: Amyloid ß-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimers Res Ther. 2021 Apr 19; 13(1):83. Shin WS, Di J, Cao Q, Li B, Seidler PM, Murray KA, Bitan G, Jiang L. PMID: 33879220.

View in: PubMed Mentions: Fields:
Neu Neurology
Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J Biol Chem. 2020 07 31; 295(31):10662-10676. Abskharon R, Seidler PM, Sawaya MR, Cascio D, Yang TP, Philipp S, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Felgner PL, Nakajima R, Glabe CG, Eisenberg DS. PMID: 32493775.

View in: PubMed Mentions: 4 Fields:
Bio Biochemistry
Translation:Humans Cells
Amyloid ß-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimers Res Ther. 2019 10 18; 11(1):86. Shin WS, Di J, Cao Q, Li B, Seidler PM, Murray KA, Bitan G, Jiang L. PMID: 31627745.

View in: PubMed Mentions: 15 Fields:
Neu Neurology
Translation:Humans Cells
Structure-based inhibitors of amyloid beta core suggest a common interface with tau. Elife. 2019 10 15; 8. Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS. PMID: 31612856.

View in: PubMed Mentions: 14 Fields:
Bio Biology
Translation:Humans Animals Cells
Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. J Biol Chem. 2019 11 01; 294(44):16451-16464. Seidler PM, Boyer DR, Murray KA, Yang TP, Bentzel M, Sawaya MR, Rosenberg G, Cascio D, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Eisenberg DS. PMID: 31537646.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry
Translation:Humans Cells
Common fibrillar spines of amyloid-ß and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J Biol Chem. 2018 02 23; 293(8):2888-2902. Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. PMID: 29282295.

View in: PubMed Mentions: 15 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Structure-based inhibitors of tau aggregation. Nat Chem. 2018 02; 10(2):170-176. Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS. PMID: 29359764.

View in: PubMed Mentions: 56 Fields:
Che Chemistry
Translation:Humans Cells
Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat Methods. 2017 Feb 13; 14(4):399-402. de la Cruz MJ, Hattne J, Shi D, Seidler P, Rodriguez J, Reyes FE, Sawaya MR, Cascio D, Weiss SC, Kim SK, Hinck CS, Hinck AP, Calero G, Eisenberg D, Gonen T. PMID: 28192420.

View in: PubMed Mentions: 54 Fields:
Cli Clinical Laboratory Techniques
Translation:Cells
Characterization of the Grp94/OS-9 chaperone-lectin complex. J Mol Biol. 2014 Oct 23; 426(21):3590-605. Seidler PM, Shinsky SA, Hong F, Li Z, Cosgrove MS, Gewirth DT. PMID: 25193139.

View in: PubMed Mentions: 6 Fields:
Mol Molecular Biology
Translation:Humans Animals Cells
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat Chem Biol. 2013 Nov; 9(11):677-84. Patel PD, Yan P, Seidler PM, Patel HJ, Sun W, Yang C, Que NS, Taldone T, Finotti P, Stephani RA, Gewirth DT, Chiosis G. PMID: 23995768.

View in: PubMed Mentions: 78 Fields:
Bio Biology Che Chemistry
Translation:Humans
Investigations of chemical modifications of amino-terminated organic films on silicon substrates and controlled protein immobilization. Langmuir. 2010 Feb 16; 26(4):2599-608. Kim J, Cho J, Seidler PM, Kurland NE, Yadavalli VK. PMID: 20095550.

View in: PubMed Mentions: 14 Fields:
Che Chemistry
Translation:Animals
Formation, structure, and reactivity of amino-terminated organic films on silicon substrates. J Colloid Interface Sci. 2009 Jan 01; 329(1):114-9. Kim J, Seidler P, Wan LS, Fill C. PMID: 18930465.

View in: PubMed Mentions: 16 Fields:
Che Chemistry
Distal His----Arg mutation in bovine myoglobin results in a ligand binding site similar to the abnormal beta site of hemoglobin Zurich (beta 63 His----Arg). Biochem Biophys Res Commun. 1989 Jan 16; 158(1):110-4. Shimada H, Dong A, Matsushima-Hibiya Y, Ishimura Y, Caughey WS. PMID: 33688654.

View in: PubMed Mentions: