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Paul Seidler

Title(s)Assistant Professor of Pharmacology and Pharmaceutical Sciences
AddressPSC 530
Health Sciences Campus
Los Angeles CA 90089-9121
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J Biol Chem. 2020 07 31; 295(31):10662-10676. Abskharon R, Seidler PM, Sawaya MR, Cascio D, Yang TP, Philipp S, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Felgner PL, Nakajima R, Glabe CG, Eisenberg DS. PMID: 32493775.
      View in: PubMed   Mentions: 1     Fields:    
    2. Amyloid ß-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation. Alzheimers Res Ther. 2019 10 18; 11(1):86. PMID: 31627745.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    3. Structure-based inhibitors of amyloid beta core suggest a common interface with tau. Elife. 2019 10 15; 8. Griner SL, Seidler P, Bowler J, Murray KA, Yang TP, Sahay S, Sawaya MR, Cascio D, Rodriguez JA, Philipp S, Sosna J, Glabe CG, Gonen T, Eisenberg DS. PMID: 31612856.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    4. Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples. J Biol Chem. 2019 11 01; 294(44):16451-16464. Seidler PM, Boyer DR, Murray KA, Yang TP, Bentzel M, Sawaya MR, Rosenberg G, Cascio D, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Eisenberg DS. PMID: 31537646.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    5. Common fibrillar spines of amyloid-ß and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J Biol Chem. 2018 02 23; 293(8):2888-2902. Krotee P, Griner SL, Sawaya MR, Cascio D, Rodriguez JA, Shi D, Philipp S, Murray K, Saelices L, Lee J, Seidler P, Glabe CG, Jiang L, Gonen T, Eisenberg DS. PMID: 29282295.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    6. Structure-based inhibitors of tau aggregation. Nat Chem. 2018 02; 10(2):170-176. Seidler PM, Boyer DR, Rodriguez JA, Sawaya MR, Cascio D, Murray K, Gonen T, Eisenberg DS. PMID: 29359764.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    7. Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat Methods. 2017 Feb 13; 14(4):399-402. PMID: 28192420.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    8. Characterization of the Grp94/OS-9 chaperone-lectin complex. J Mol Biol. 2014 Oct 23; 426(21):3590-605. PMID: 25193139.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    9. Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat Chem Biol. 2013 Nov; 9(11):677-84. PMID: 23995768.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    10. Investigations of chemical modifications of amino-terminated organic films on silicon substrates and controlled protein immobilization. Langmuir. 2010 Feb 16; 26(4):2599-608. PMID: 20095550.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    11. Formation, structure, and reactivity of amino-terminated organic films on silicon substrates. J Colloid Interface Sci. 2009 Jan 01; 329(1):114-9. PMID: 18930465.
      View in: PubMed   Mentions: 13     Fields:    
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