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An Artificial Intelligence-Supported Medicinal Chemistry Project: An Example for Incorporating Artificial Intelligence Within the Pharmacy Curriculum. Am J Pharm Educ. 2024 May; 88(5):100696.
Culp ML, Mahmoud S, Liu D, Haworth IS. PMID: 38574998.
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PubMed Mentions: Fields:
Translation:
Humans
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Pharmacokinetic model of human exposure to ciprofloxacin through consumption of fish. Environ Toxicol Pharmacol. 2024 Mar; 106:104359.
Kum OK, Chan KM, Morningstar-Kywi N, MacKay JA, Haworth IS. PMID: 38163528.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Teaching of drug disposition using physiologically based pharmacokinetic modeling software: GastroPlus as an educational tool. Adv Physiol Educ. 2023 Dec 01; 47(4):718-725.
Morningstar-Kywi N, Morris DN, Romero RM, Haworth IS. PMID: 37471218.
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PubMed Mentions: Fields:
Translation:
Humans
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Prediction of Peptide and TCR CDR3 Loops in Formation of Class I MHC-Peptide-TCR Complexes Using Molecular Models with Solvation. Methods Mol Biol. 2023; 2673:273-287.
Mehta NM, Li Y, Patel V, Li W, Morningstar-Kywi N, Pospiech M, Alachkar H, Haworth IS. PMID: 37258921; PMCID: PMC11059237.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
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Prediction of Water Distributions and Displacement at Protein-Ligand Interfaces. J Chem Inf Model. 2022 03 28; 62(6):1489-1497.
Morningstar-Kywi N, Wang K, Asbell TR, Wang Z, Giles JB, Lai J, Brill D, Sutch BT, Haworth IS. PMID: 35261241.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
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Assessment of the impact of co-curricular activities on achievement of Doctor of Pharmacy program outcomes. Curr Pharm Teach Learn. 2022 04; 14(4):440-448.
Matthews ME, Avoundjian A, Ameripour D, Fakolade W, Wu M, Haworth IS. PMID: 35483809.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Lysine acetylation regulates the interaction between proteins and membranes. Nat Commun. 2021 11 09; 12(1):6466.
Okada AK, Teranishi K, Ambroso MR, Isas JM, Vazquez-Sarandeses E, Lee JY, Melo AA, Pandey P, Merken D, Berndt L, Lammers M, Daumke O, Chang K, Haworth IS, Langen R. PMID: 34753925; PMCID: PMC8578602.
View in:
PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Integration of Clinical and Scientific Principles in the Teaching of Drug-Drug Interactions. Med Sci Educ. 2021 Dec; 31(6):2169-2176.
Kim RE, Morningstar-Kywi N, Haworth IS. PMID: 34956730; PMCID: PMC8651912.
View in:
PubMed Mentions:
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Ligand-specific pharmacogenetic effects of nonsynonymous mutations. Pharmacogenet Genomics. 2021 06 01; 31(4):75-82.
Morningstar-Kywi N, Haworth IS, Mosley SA. PMID: 33395026.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Corrigendum to "Naturally occurring sesquiterpene lactones and their semi-synthetic derivatives modulate PGE2 levels by decreasing COX2 activity and expression" [Heliyon 5 (3) (March 2019) e01366]. Heliyon. 2019 04; 5(4):e01513.
Perri F, Frattaruolo L, Haworth I, Brindisi M, El-Magboub A, Ferrario A, Gomer C, Aiello F, Adams JD. PMID: 31049429; PMCID: PMC6482316.
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PubMed Mentions:
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Experimental Validation of the ALLNOX Program for Studying Protein-Nucleic Acid Complexes. J Phys Chem A. 2019 Apr 25; 123(16):3592-3598.
Ding Y, Kathiresan V, Zhang X, Haworth IS, Qin PZ. PMID: 30978022; PMCID: PMC6486822.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Naturally occurring sesquiterpene lactones and their semi-synthetic derivatives modulate PGE2 levels by decreasing COX2 activity and expression. Heliyon. 2019 03; 5(3):e01366.
Perri F, Frattaruolo L, Haworth I, Brindisi M, El-magboub A, Ferrario A, Gomer C, Aiello F, Adams JD. PMID: 30976671; PMCID: PMC6441754.
View in:
PubMed Mentions:
10
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A curcumin-diglutaric acid conjugated prodrug with improved water solubility and antinociceptive properties compared to curcumin. Biosci Biotechnol Biochem. 2018 Aug; 82(8):1301-1308.
Muangnoi C, Jithavech P, Ratnatilaka Na Bhuket P, Supasena W, Wichitnithad W, Towiwat P, Niwattisaiwong N, Haworth IS, Rojsitthisak P. PMID: 29678124.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimals
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Rational drug design and synthesis of new α-Santonin derivatives as potential COX-2 inhibitors. Bioorg Med Chem Lett. 2018 04 01; 28(6):993-996.
Coricello A, El-Magboub A, Luna M, Ferrario A, Haworth IS, Gomer CJ, Aiello F, Adams JD. PMID: 29501395.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 2. Rational Bioavailability Design by Global Sensitivity Analysis To Identify Properties Affecting Bioavailability. Mol Pharm. 2018 03 05; 15(3):831-839.
Daga PR, Bolger MB, Haworth IS, Clark RD, Martin EJ. PMID: 29337562.
View in:
PubMed Mentions:
8 Fields:
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Physiologically Based Pharmacokinetic Modeling in Lead Optimization. 1. Evaluation and Adaptation of GastroPlus To Predict Bioavailability of Medchem Series. Mol Pharm. 2018 03 05; 15(3):821-830.
Daga PR, Bolger MB, Haworth IS, Clark RD, Martin EJ. PMID: 29337578.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Enhancement of Curcumin Bioavailability Via the Prodrug Approach: Challenges and Prospects. Eur J Drug Metab Pharmacokinet. 2017 Jun; 42(3):341-353.
Ratnatilaka Na Bhuket P, El-Magboub A, Haworth IS, Rojsitthisak P. PMID: 27683187.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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Computer Modeling of Spin Labels: NASNOX, PRONOX, and ALLNOX. Methods Enzymol. 2015; 563:569-93.
Beasley KN, Sutch BT, Hatmal MM, Langen R, Qin PZ, Haworth IS. PMID: 26478499.
View in:
PubMed Mentions:
12 Fields:
-
Structural Characterization of Membrane-Curving Proteins: Site-Directed Spin Labeling, EPR, and Computational Refinement. Methods Enzymol. 2015; 564:259-88.
Ambroso MR, Haworth IS, Langen R. PMID: 26477254.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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An Integrated Spin-Labeling/Computational-Modeling Approach for Mapping Global Structures of Nucleic Acids. Methods Enzymol. 2015; 564:427-53.
Tangprasertchai NS, Zhang X, Ding Y, Tham K, Rohs R, Haworth IS, Qin PZ. PMID: 26477260; PMCID: PMC4641853.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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The role of the C-terminal helix of U1A protein in the interaction with U1hpII RNA. Nucleic Acids Res. 2013 Aug; 41(14):7092-100.
Law MJ, Lee DS, Lee CS, Anglim PP, Haworth IS, Laird-Offringa IA. PMID: 23703211; PMCID: PMC3737524.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
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Electrophoretic mobility of duplex DNA cross-linked by mechlorethamine at a cytosine-cytosine mismatch pair. Electrophoresis. 2013 Mar; 34(6):917-24.
Romero RM, Rojsittisak P, Haworth IS. PMID: 23334930.
View in:
PubMed Mentions:
2 Fields:
Translation:
Cells
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Idealized models of protofilaments of human islet amyloid polypeptide. J Chem Inf Model. 2012 Nov 26; 52(11):2983-91.
Li Y, Hatmal MM, Langen R, Haworth IS. PMID: 23116372; PMCID: PMC3522432.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Nitroxide sensing of a DNA microenvironment: mechanistic insights from EPR spectroscopy and molecular dynamics simulations. J Phys Chem B. 2012 Jun 07; 116(22):6387-96.
Popova AM, Hatmal MM, Frushicheva MP, Price EA, Qin PZ, Haworth IS. PMID: 22574834; PMCID: PMC3382087.
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PubMed Mentions:
5 Fields:
Translation:
Cells
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Global structure of a three-way junction in a phi29 packaging RNA dimer determined using site-directed spin labeling. J Am Chem Soc. 2012 Feb 08; 134(5):2644-52.
Zhang X, Tung CS, Sowa GZ, Hatmal MM, Haworth IS, Qin PZ. PMID: 22229766; PMCID: PMC3279945.
View in:
PubMed Mentions:
25 Fields:
Translation:
Cells
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Information intervention in the pharmaceutical sciences. Med Ref Serv Q. 2012; 31(2):188-201.
Chatfield AJ, Romero RM, Haworth IS. PMID: 22559181.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Fibril structure of human islet amyloid polypeptide. J Biol Chem. 2012 Feb 17; 287(8):5235-41.
Bedrood S, Li Y, Isas JM, Hegde BG, Baxa U, Haworth IS, Langen R. PMID: 22187437; PMCID: PMC3285303.
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PubMed Mentions:
67 Fields:
Translation:
HumansCells
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Computer modeling of nitroxide spin labels on proteins. Biopolymers. 2012 Jan; 97(1):35-44.
Hatmal MM, Li Y, Hegde BG, Hegde PB, Jao CC, Langen R, Haworth IS. PMID: 21792846; PMCID: PMC3422567.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Modeling of the water network at protein-RNA interfaces. J Chem Inf Model. 2011 Jun 27; 51(6):1347-52.
Li Y, Sutch BT, Bui HH, Gallaher TK, Haworth IS. PMID: 21612274.
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PubMed Mentions:
7 Fields:
Translation:
Cells
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HPLC-UV, MALDI-TOF-MS and ESI-MS/MS analysis of the mechlorethamine DNA crosslink at a cytosine-cytosine mismatch pair. PLoS One. 2011; 6(6):e20745.
Rojsitthisak P, Jongaroonngamsang N, Romero RM, Haworth IS. PMID: 21673963; PMCID: PMC3108972.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Functional role of the intracellular loop linking transmembrane domains 6 and 7 of the human dipeptide transporter hPEPT1. J Membr Biol. 2010 Dec; 238(1-3):43-9.
Xu L, Li Y, Haworth IS, Davies DL. PMID: 21104182; PMCID: PMC3032433.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Quantitative assessment of assisted problem-based learning in a pharmaceutics course. Am J Pharm Educ. 2010 May 12; 74(4):66.
Romero RM, Eriksen SP, Haworth IS. PMID: 20585427; PMCID: PMC2879117.
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PubMed Mentions:
19 Fields:
Translation:
Humans
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Roles of amphipathic helices and the bin/amphiphysin/rvs (BAR) domain of endophilin in membrane curvature generation. J Biol Chem. 2010 Jun 25; 285(26):20164-70.
Jao CC, Hegde BG, Gallop JL, Hegde PB, McMahon HT, Haworth IS, Langen R. PMID: 20418375; PMCID: PMC2888429.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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Similarity of protein-RNA interfaces based on motif analysis. J Chem Inf Model. 2009 Sep; 49(9):2139-46.
Sutch BT, Chambers EJ, Bayramyan MZ, Gallaher TK, Haworth IS. PMID: 19731952.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Mutagenesis and cysteine scanning of transmembrane domain 10 of the human dipeptide transporter. Pharm Res. 2009 Oct; 26(10):2358-66.
Xu L, Haworth IS, Kulkarni AA, Bolger MB, Davies DL. PMID: 19685173; PMCID: PMC2861424.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites. J Biol Chem. 2009 Mar 13; 284(11):7157-64.
Tsai AG, Engelhart AE, Hatmal MM, Houston SI, Hud NV, Haworth IS, Lieber MR. PMID: 19106104; PMCID: PMC2652318.
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PubMed Mentions:
28 Fields:
Translation:
HumansCells
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Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):19666-71.
Jao CC, Hegde BG, Chen J, Haworth IS, Langen R. PMID: 19066219; PMCID: PMC2605001.
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PubMed Mentions:
262 Fields:
Translation:
HumansCells
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Ethanol inhibits functional activity of the human intestinal dipeptide transporter hPepT1 expressed in Xenopus oocytes. Alcohol Clin Exp Res. 2008 May; 32(5):777-84.
Li K, Xu L, Kulkarni AA, Perkins DI, Haworth IS, Davies DL. PMID: 18336632; PMCID: PMC2861421.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Incorporation of zebularine from its 2'-deoxyribonucleoside triphosphate derivative and activity as a template-coding nucleobase. Nucleosides Nucleotides Nucleic Acids. 2008 Feb; 27(2):131-45.
Dowd CL, Sutch BT, Haworth IS, Eritja R, Marquez VE, Yang AS. PMID: 18205068.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
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WATGEN: an algorithm for modeling water networks at protein-protein interfaces. J Comput Chem. 2007 Nov 15; 28(14):2241-51.
Bui HH, Schiewe AJ, Haworth IS. PMID: 17471455.
View in:
PubMed Mentions:
10 Fields:
Translation:
Cells
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Computation of nitroxide-nitroxide distances in spin-labeled DNA duplexes. Biopolymers. 2007 Sep; 87(1):40-50.
Price EA, Sutch BT, Cai Q, Qin PZ, Haworth IS. PMID: 17538992; PMCID: PMC2430107.
View in:
PubMed Mentions:
16 Fields:
Translation:
Cells
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Nanometer distance measurements in RNA using site-directed spin labeling. Biophys J. 2007 Sep 15; 93(6):2110-7.
Cai Q, Kusnetzow AK, Hideg K, Price EA, Haworth IS, Qin PZ. PMID: 17526583; PMCID: PMC1959523.
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PubMed Mentions:
29 Fields:
Translation:
Cells
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Structure-based prediction of MHC-peptide association: algorithm comparison and application to cancer vaccine design. J Mol Graph Model. 2007 Oct; 26(3):667-75.
Schiewe AJ, Haworth IS. PMID: 17493854.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Cysteine scanning of transmembrane domain three of the human dipeptide transporter: implications for substrate transport. J Drug Target. 2007 Apr; 15(3):218-25.
Links JL, Kulkarni AA, Davies DL, Lee VH, Haworth IS. PMID: 17454359.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Measuring nanometer distances in nucleic acids using a sequence-independent nitroxide probe. Nat Protoc. 2007; 2(10):2354-65.
Qin PZ, Haworth IS, Cai Q, Kusnetzow AK, Grant GP, Price EA, Sowa GZ, Popova A, Herreros B, He H. PMID: 17947978; PMCID: PMC2430106.
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PubMed Mentions:
40 Fields:
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A charge pair interaction between Arg282 in transmembrane segment 7 and Asp341 in transmembrane segment 8 of hPepT1. Pharm Res. 2007 Jan; 24(1):66-72.
Kulkarni AA, Davies DL, Links JS, Patel LN, Lee VH, Haworth IS. PMID: 17009102.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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Computational drug delivery. Adv Drug Deliv Rev. 2006 Nov 30; 58(12-13):1271-3.
Haworth IS. PMID: 17069930.
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PubMed Mentions: Fields:
Translation:
Humans
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Site-directed spin labeling measurements of nanometer distances in nucleic acids using a sequence-independent nitroxide probe. Nucleic Acids Res. 2006; 34(17):4722-30.
Cai Q, Kusnetzow AK, Hubbell WL, Haworth IS, Gacho GP, Van Eps N, Hideg K, Chambers EJ, Qin PZ. PMID: 16966338; PMCID: PMC1635252.
View in:
PubMed Mentions:
50 Fields:
Translation:
Cells
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Structural prediction of peptides binding to MHC class I molecules. Proteins. 2006 Apr 01; 63(1):43-52.
Bui HH, Schiewe AJ, von Grafenstein H, Haworth IS. PMID: 16447245.
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PubMed Mentions:
22 Fields:
Translation:
HumansCells
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The role of positively charged amino acids and electrostatic interactions in the complex of U1A protein and U1 hairpin II RNA. Nucleic Acids Res. 2006; 34(1):275-85.
Law MJ, Linde ME, Chambers EJ, Oubridge C, Katsamba PS, Nilsson L, Haworth IS, Laird-Offringa IA. PMID: 16407334; PMCID: PMC1326249.
View in:
PubMed Mentions:
42 Fields:
Translation:
Cells
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Kinetic analysis of the role of the tyrosine 13, phenylalanine 56 and glutamine 54 network in the U1A/U1 hairpin II interaction. Nucleic Acids Res. 2005; 33(9):2917-28.
Law MJ, Chambers EJ, Katsamba PS, Haworth IS, Laird-Offringa IA. PMID: 15914668; PMCID: PMC1140079.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Physicochemical and structural characterization of quercetin-beta-cyclodextrin complexes. J Pharm Sci. 2005 May; 94(5):1079-89.
Zheng Y, Haworth IS, Zuo Z, Chow MS, Chow AH. PMID: 15793810.
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PubMed Mentions:
20 Fields:
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Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation. J Biol Chem. 2005 Jun 17; 280(24):22749-60.
Raghavan SC, Chastain P, Lee JS, Hegde BG, Houston S, Langen R, Hsieh CL, Haworth IS, Lieber MR. PMID: 15840562.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Fine-structure analysis of activation-induced deaminase accessibility to class switch region R-loops. Mol Cell Biol. 2005 Mar; 25(5):1730-6.
Yu K, Roy D, Bayramyan M, Haworth IS, Lieber MR. PMID: 15713630; PMCID: PMC549380.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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Stability and strand asymmetry in the non-B DNA structure at the bcl-2 major breakpoint region. J Biol Chem. 2004 Oct 29; 279(44):46213-25.
Raghavan SC, Houston S, Hegde BG, Langen R, Haworth IS, Lieber MR. PMID: 15328356.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
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Analysis of transmembrane segment 7 of the dipeptide transporter hPepT1 by cysteine-scanning mutagenesis. J Biol Chem. 2003 Dec 19; 278(51):51833-40.
Kulkarni AA, Haworth IS, Uchiyama T, Lee VH. PMID: 14532279.
View in:
PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Computation of DNA backbone conformations. J Biomol Struct Dyn. 2003 Aug; 21(1):111-25.
Chambers EJ, Price EA, Bayramyan MC, Haworth IS. PMID: 12854963.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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Transmembrane segment 5 of the dipeptide transporter hPepT1 forms a part of the substrate translocation pathway. Biochem Biophys Res Commun. 2003 Jun 20; 306(1):177-85.
Kulkarni AA, Haworth IS, Lee VH. PMID: 12788085.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Complex role of the beta 2-beta 3 loop in the interaction of U1A with U1 hairpin II RNA. J Biol Chem. 2002 Sep 06; 277(36):33267-74.
Katsamba PS, Bayramyan M, Haworth IS, Myszka DG, Laird-Offringa IA. PMID: 12082087.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Extrahelical cytosine bases in DNA duplexes containing d[GCC](n).d[GCC](n) repeats: detection by a mechlorethamine crosslinking reaction. Nucleic Acids Res. 2001 Nov 15; 29(22):4716-23.
Rojsitthisak P, Romero RM, Haworth IS. PMID: 11713322; PMCID: PMC92524.
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PubMed Mentions:
4 Fields:
Translation:
Cells
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DNA interstrand crosslink formation by mechlorethamine at a cytosine-cytosine mismatch pair: kinetics and sequence dependence. Arch Biochem Biophys. 2001 Feb 15; 386(2):143-53.
Romero RM, Rojsitthisak P, Haworth IS. PMID: 11368336.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Water dynamics at the binding interface of four different HLA-A2-peptide complexes. Int Immunol. 2000 Jul; 12(7):949-57.
Meng WS, von Grafenstein H, Haworth IS. PMID: 10882406.
View in:
PubMed Mentions:
6 Fields:
Translation:
Cells
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DNA structure control by polycationic species: polyamine, cobalt ammines, and di-metallo transition metal chelates. Chirality. 2000 May; 12(4):221-36.
Rodger A, Sanders KJ, Hannon MJ, Meistermann I, Parkinson A, Vidler DS, Haworth IS. PMID: 10790193.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
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Experimental evidence for the presence of a water network at the peptide-MHC interface. Immunol Lett. 1999 Dec 01; 70(3):139-41.
Gurlo T, Meng WS, Bui HH, Haworth IS, von Grafenstein H. PMID: 10656665.
View in:
PubMed Mentions:
1 Fields:
Translation:
Cells
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Biopharmaceutics of transmucosal peptide and protein drug administration: role of transport mechanisms with a focus on the involvement of PepT1. J Control Release. 1999 Nov 01; 62(1-2):129-40.
Lee VH, Chu C, Mahlin ED, Basu SK, Ann DK, Bolger MB, Haworth IS, Yeung AK, Wu SK, Hamm-Alvarez S, Okamoto CT. PMID: 10518644.
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PubMed Mentions:
11 Fields:
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DNA Binding of Ruthenium Tris(1,10-phenanthroline): Evidence for the Dependence of Binding Mode on Metal Complex Concentration. Inorg Chem. 1999 Oct 04; 38(20):4486-4497.
Coggan DZ, Haworth IS, Bates PJ, Robinson A, Rodger A. PMID: 11671161.
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PubMed Mentions:
10 Fields:
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Spermine inhibition of the 2,5-diaziridinyl-1,4-benzoquinone (DZQ) crosslinking reaction with DNA duplexes containing poly(purine). poly(pyrimidine) tracts. Nucleic Acids Res. 1999 Jul 01; 27(13):2601-9.
Shamma T, Haworth IS. PMID: 10373575; PMCID: PMC148467.
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PubMed Mentions:
3 Fields:
-
Anomalous cross-linking by mechlorethamine of DNA duplexes containing C-C mismatch pairs. Biochemistry. 1999 Mar 23; 38(12):3641-8.
Romero RM, Mitas M, Haworth IS. PMID: 10090751.
View in:
PubMed Mentions:
4 Fields:
Translation:
Cells
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Structure, function, and molecular modeling approaches to the study of the intestinal dipeptide transporter PepT1. J Pharm Sci. 1998 Nov; 87(11):1286-91.
Bolger MB, Haworth IS, Yeung AK, Ann D, von Grafenstein H, Hamm-Alvarez S, Okamoto CT, Kim KJ, Basu SK, Wu S, Lee VH. PMID: 9811478.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Proton-driven dipeptide uptake in primary cultured rabbit conjunctival epithelial cells. Invest Ophthalmol Vis Sci. 1998 Nov; 39(12):2365-73.
Basu SK, Haworth IS, Bolger MB, Lee VH. PMID: 9804145.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Molecular identification of a role for tyrosine 167 in the function of the human intestinal proton- coupled dipeptide transporter (hPepT1). Biochem Biophys Res Commun. 1998 Sep 08; 250(1):103-7.
Yeung AK, Basu SK, Wu SK, Chu C, Okamoto CT, Hamm-Alvarez SF, von Grafenstein H, Shen WC, Kim KJ, Bolger MB, Haworth IS, Ann DK, Lee VH. PMID: 9735340.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
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A model of water structure inside the HLA-A2 peptide binding groove. Int Immunol. 1997 Sep; 9(9):1339-46.
Meng WS, von Grafenstein H, Haworth IS. PMID: 9310837.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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At physiological pH, d(CCG)15 forms a hairpin containing protonated cytosines and a distorted helix. Biochemistry. 1997 Mar 25; 36(12):3687-99.
Yu A, Barron MD, Romero RM, Christy M, Gold B, Dai J, Gray DM, Haworth IS, Mitas M. PMID: 9132022.
View in:
PubMed Mentions:
37 Fields:
Translation:
Cells
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Spermine binding to GC-rich DNA: experimental and theoretical studies. Arch Biochem Biophys. 1996 Jan 01; 325(1):39-46.
Yuki M, Grukhin V, Lee CS, Haworth IS. PMID: 8554341.
View in:
PubMed Mentions:
3 Fields:
Translation:
Cells
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The trinucleotide repeat sequence d(CGG)15 forms a heat-stable hairpin containing Gsyn. Ganti base pairs. Biochemistry. 1995 Oct 03; 34(39):12803-11.
Mitas M, Yu A, Dill J, Haworth IS. PMID: 7548035.
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PubMed Mentions:
50 Fields:
Translation:
Cells
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Molecular cloning, characterization, and mapping of a full-length cDNA encoding human UDP-galactose 4'-epimerase. Biochem Mol Med. 1995 Oct; 56(1):1-7.
Daude N, Gallaher TK, Zeschnigk M, Starzinski-Powitz A, Petry KG, Haworth IS, Reichardt JK. PMID: 8593531.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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The trinucleotide repeat sequence d(GTC)15 adopts a hairpin conformation. Nucleic Acids Res. 1995 Jul 25; 23(14):2706-14.
Yu A, Dill J, Wirth SS, Huang G, Lee VH, Haworth IS, Mitas M. PMID: 7651831; PMCID: PMC307095.
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17 Fields:
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Cells
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Multiple DNA binding modes of anthracene-9-carbonyl-N1-spermine. Bioorg Med Chem. 1995 Jun; 3(6):861-72.
Rodger A, Taylor S, Adlam G, Blagbrough IS, Haworth IS. PMID: 7582962.
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7 Fields:
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Cells
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Hairpin properties of single-stranded DNA containing a GC-rich triplet repeat: (CTG)15. Nucleic Acids Res. 1995 Mar 25; 23(6):1050-9.
Mitas M, Yu A, Dill J, Kamp TJ, Chambers EJ, Haworth IS. PMID: 7731793; PMCID: PMC306804.
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51 Fields:
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HumansCells
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Molecular dynamics simulations of chlorambucil/DNA adducts. A structural basis for the 5'-GNC interstrand DNA crosslink formed by nitrogen mustards. J Biomol Struct Dyn. 1995 Feb; 12(4):911-36.
Remias MG, Lee CS, Haworth IS. PMID: 7779307.
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2 Fields:
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Cells
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Molecular dynamics simulations provide a structural basis for the experimentally observed nucleotide preferences for DNA interstrand cross-links induced by aziridinylbenzoquinones. Biochemistry. 1993 Nov 30; 32(47):12857-63.
Haworth IS, Lee CS, Yuki M, Gibson NW. PMID: 8251508.
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1 Fields:
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AnimalsCells
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A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell. 1993 Nov 05; 75(3):443-50.
Jabs EW, Müller U, Li X, Ma L, Luo W, Haworth IS, Klisak I, Sparkes R, Warman ML, Mulliken JB, et al. PMID: 8106171.
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145 Fields:
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HumansCells
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A molecular basis for human hypersensitivity to aminoglycoside antibiotics. Nucleic Acids Res. 1993 Sep 11; 21(18):4174-9.
Hutchin T, Haworth I, Higashi K, Fischel-Ghodsian N, Stoneking M, Saha N, Arnos C, Cortopassi G. PMID: 8414970; PMCID: PMC310046.
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51 Fields:
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HumansCells
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SUBCUR: visualization of structural differences between DNA duplexes. J Mol Graph. 1993 Sep; 11(3):211-3.
Sanghani SR, Elcock AH, Haworth IS. PMID: 8110667.
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HumansCells
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The DNA complexes of 2,5-diaziridinylbenzoquinone and 3,6-dimethyl-2,5-diaziridinylbenzoquinone. A molecular mechanics study. Anticancer Drug Des. 1993 Aug; 8(4):269-87.
Yuki M, Haworth IS. PMID: 8240656.
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Cells
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A molecular dynamics simulation of a polyamine-induced conformational change of DNA. A possible mechanism for the B to Z transition. J Biomol Struct Dyn. 1992 Aug; 10(1):195-211.
Haworth IS, Rodger A, Richards WG. PMID: 1418741.
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3 Fields:
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Cells
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A binding mode of lambda-[tris(1,10-phenanthroline)ruthenium(II)]2+ exhibiting preference for purine-3',5'-pyrimidine sites of DNA. J Biomol Struct Dyn. 1991 Dec; 9(3):553-69.
Haworth IS, Elcock AH, Rodger A, Richards WG. PMID: 1815643.
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Cells
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COSMIC(90): an improved molecular mechanics treatment of hydrocarbons and conjugated systems. J Comput Aided Mol Des. 1991 Oct; 5(5):475-504.
Morley SD, Abraham RJ, Haworth IS, Jackson DE, Saunders MR, Vinter JG. PMID: 1770382.
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12 Fields:
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Cells
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Sequence selective binding to the DNA major groove: tris(1,10-phenanthroline) metal complexes binding to poly(dG-dC) and poly(dA-dT). J Biomol Struct Dyn. 1991 Aug; 9(1):23-44.
Haworth IS, Elcock AH, Freeman J, Rodger A, Richards WG. PMID: 1781946.
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2 Fields:
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Cells
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A molecular mechanics study of spermine complexation to DNA: a new model for spermine-poly(dG-dC) binding. Proc Biol Sci. 1991 May 22; 244(1310):107-16.
Haworth IS, Rodger A, Richards WG. PMID: 1679544.
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4 Fields:
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Cells
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Charge calculations in molecular mechanics. Part 8. Partial atomic charges from classical calculations. J Comput Aided Mol Des. 1991 Feb; 5(1):21-39.
Abraham RJ, Grant GH, Haworth IS, Smith PE. PMID: 2072123.
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6 Fields:
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Cells
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A prototype bioreductive DNA groove binding ligand. Anticancer Drug Des. 1991 Feb; 6(1):59-70.
Haworth IS, Burt C, Gago F, Reynolds CA, Richards WG. PMID: 1707627.
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1 Fields:
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Cells
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Molecular modelling of poly(aryl ether ketones). I. Aryl..aryl interactions in crystal structures. J Comput Aided Mol Des. 1990 Sep; 4(3):283-94.
Abraham RJ, Haworth IS. PMID: 2280265.
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Cells
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A modification to the COSMIC parameterisation using ab initio constrained potential functions. J Comput Aided Mol Des. 1988 Jul; 2(2):125-35.
Abraham RJ, Haworth IS. PMID: 3199153.
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3 Fields: