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Ashley Margol, MD, MS

Title(s)Assistant Professor of Clinical Pediatrics
AddressCHLA 4650 W. Sunset Blvd.
Off Campus
Los Angeles CA 90026
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    Ashley Margol, MD is originally from Jacksonville, Florida, where she and completed her undergraduate training at the University of Florida where she majored in zoology. She moved to Los Angeles to attend medical school at the Keck School of Medicine at the University of Southern California. She did her pediatric residency at Los Angeles County-University of Southern California after which she was honored to spend a fourth year as chief resident. Ashley recently completed her pediatric hematology-oncology fellowship at Children’s Hospital Los Angeles and is currently spending an additional year at Children’s Hospital Los Angeles training in pediatric neuro-oncology. Her research is examining the presence and role of inflammation in pediatric medulloblastoma, and she will complete her Masters of Science in Clinical, Biomedical and Translational Research this fall.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors. Neuro Oncol. 2020 Jul 07; 22(7):944-954. Hoffman LM, Richardson EA, Ho B, Margol A, Reddy A, Lafay-Cousin L, Chi S, Slavc I, Judkins A, Hasselblatt M, Bourdeaut F, Frühwald MC, Vibhakar R, Bouffet E, Huang A. PMID: 32129445.
      View in: PubMed   Mentions:    Fields:    
    2. Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics. Pediatr Blood Cancer. 2020 Jun 23; e28516. Kuo C, Foon D, Waters K, Cheung C, Margol AS. PMID: 32573959.
      View in: PubMed   Mentions:    Fields:    
    3. SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors. Neuro Oncol. 2020 Jun 09; 22(6):785-796. Panwalkar P, Pratt D, Chung C, Dang D, Le P, Martinez D, Bayliss JM, Smith KS, Adam M, Potter S, Northcott PA, Mascarenhas L, Shows J, Pawel B, Margol A, Huang A, Judkins AR, Venneti S. PMID: 31912158.
      View in: PubMed   Mentions: 1     Fields:    
    4. A genome-wide association study on medulloblastoma. J Neurooncol. 2020 Apr; 147(2):309-315. Dahlin AM, Wibom C, Andersson U, Bybjerg-Grauholm J, Deltour I, Hougaard DM, Scheurer ME, Lau CC, McKean-Cowdin R, Kennedy RJ, Hung LT, Yee J, Margol AS, Barrington-Trimis J, Gauderman WJ, Feychting M, Schüz J, Röösli M, Kjaerheim K, Januszkiewicz-Lewandowska D, Fichna M, Nowak J, Searles Nielsen S, Asgharzadeh S, Mirabello L, Hjalmars U, Melin B. PMID: 32056145.
      View in: PubMed   Mentions:    Fields:    
    5. Primary diffuse leptomeningeal glioneuronal tumors of the central nervous system: Report of three cases and review of literature. Pediatr Hematol Oncol. 2020 Apr; 37(3):248-258. Abongwa C, Cotter J, Tamrazi B, Dhall G, Davidson T, Margol A. PMID: 31951480.
      View in: PubMed   Mentions:    Fields:    
    6. Prognostic significance of molecular subgroups of medulloblastoma in young children receiving irradiation-sparing regimens. J Neurooncol. 2019 Nov; 145(2):375-383. Yeo KK, Margol AS, Kennedy RJ, Hung L, Robison NJ, Dhall G, Asgharzadeh S. PMID: 31621042.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Clinical and neuropsychological outcome of pediatric non-midline central nervous system germinoma treated with chemotherapy and reduced dose/volume irradiation: The Children's Hospital Los Angeles experience. Pediatr Blood Cancer. 2019 12; 66(12):e27983. Yeo KK, Kayser K, Margol AS, Wong KK, Robison N, Finlay J, Dhall G. PMID: 31502379.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Pediatric Atypical Teratoid/Rhabdoid Tumors of the Brain: Identification of Metabolic Subgroups Using In Vivo 1H-MR Spectroscopy. AJNR Am J Neuroradiol. 2019 05; 40(5):872-877. Tamrazi B, Venneti S, Margol A, Hawes D, Cen SY, Nelson M, Judkins A, Biegel J, Blüml S. PMID: 30948375.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy. Oncotarget. 2019 Jan 11; 10(4):551-557. Toll SA, Tran HN, Cotter J, Judkins AR, Tamrazi B, Biegel JA, Dhall G, Robison NJ, Waters K, Patel P, Cooper R, Margol AS. PMID: 30728904.
      View in: PubMed   Mentions: 4     Fields:    
    10. A comparative analysis of clinicopathological features and survival among early adolescents/young adults and children with low-grade glioma: a report from the Children's Oncology Group. J Neurooncol. 2018 Dec; 140(3):575-582. Margol AS, Yeo KK, Xia C, Onar A, Robison NJ, Freyer DR, Dhall G. PMID: 30173409.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Transmission of a TP53 germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner. Cold Spring Harb Mol Case Stud. 2018 04; 4(2). Cotter JA, Szymanski L, Karimov C, Boghossian L, Margol A, Dhall G, Tamrazi B, Varaprasathan GI, Parham DM, Judkins AR, Biegel JA. PMID: 29581140.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Phase I trial of dasatinib, lenalidomide, and temozolomide in children with relapsed or refractory central nervous system tumors. J Neurooncol. 2018 May; 138(1):199-207. Robison NJ, Yeo KK, Berliner AP, Malvar J, Sheard MA, Margol AS, Seeger RC, Rushing T, Finlay JL, Sposto R, Dhall G. PMID: 29427149.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsCTClinical Trials
    13. Palliative Care Options for a Young Adult Patient with a Diffuse Intrinsic Pontine Glioma. Cureus. 2017 Aug 18; 9(8):e1580. Sison J, Tran H, Margol A, Tiwari N, Garcia KM, Cotter J, Kiehna E, Olch AJ, Wong K. PMID: 29057192.
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    14. Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome. Acta Neuropathol. 2017 11; 134(5):705-714. Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C, Yip S, Hukin J, Sun Y, Schipper MJ, Chavez L, Margol A, Pekmezci M, Chung C, Banda A, Bayliss JM, Curry SJ, Santi M, Rodriguez FJ, Snuderl M, Karajannis MA, Saratsis AM, Horbinski CM, Carret AS, Wilson B, Johnston D, Lafay-Cousin L, Zelcer S, Eisenstat D, Silva M, Scheinemann K, Jabado N, McNeely PD, Kool M, Pfister SM, Taylor MD, Hawkins C, Korshunov A, Judkins AR, Venneti S. PMID: 28733933.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    15. Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach. J Neurooncol. 2017 05; 133(1):119-128. Fay-McClymont TB, Ploetz DM, Mabbott D, Walsh K, Smith A, Chi SN, Wells E, Madden J, Margol A, Finlay J, Kieran MW, Strother D, Dhall G, Packer RJ, Foreman NK, Bouffet E, Lafay-Cousin L. PMID: 28405869.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Sci Transl Med. 2016 11 23; 8(366):366ra161. Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, La Rocca G, Santi M, Lewis PW, Hawkins C, Melnick A, David Allis C, Thompson CB, Chinnaiyan AM, Judkins AR, Venneti S. PMID: 27881822.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    17. Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy. Pediatr Blood Cancer. 2016 09; 63(9):1527-34. Lafay-Cousin L, Smith A, Chi SN, Wells E, Madden J, Margol A, Ramaswamy V, Finlay J, Taylor MD, Dhall G, Strother D, Kieran MW, Foreman NK, Packer RJ, Bouffet E. PMID: 27145464.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    18. Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia. Front Oncol. 2015; 5:191. Xu J, Margol AS, Shukla A, Ren X, Finlay JL, Krieger MD, Gilles FH, Couch FJ, Aziz M, Fung ET, Asgharzadeh S, Barrett MT, Erdreich-Epstein A. PMID: 26380221.
      View in: PubMed   Mentions:
    19. Molecular subgroups of medulloblastoma identification using noninvasive magnetic resonance spectroscopy. Neuro Oncol. 2016 Jan; 18(1):126-31. Blüml S, Margol AS, Sposto R, Kennedy RJ, Robison NJ, Vali M, Hung LT, Muthugounder S, Finlay JL, Erdreich-Epstein A, Gilles FH, Judkins AR, Krieger MD, Dhall G, Nelson MD, Asgharzadeh S. PMID: 26254476.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    20. Achieving target voriconazole concentrations more accurately in children and adolescents. Antimicrob Agents Chemother. 2015; 59(6):3090-7. Neely M, Margol A, Fu X, van Guilder M, Bayard D, Schumitzky A, Orbach R, Liu S, Louie S, Hope W. PMID: 25779580.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    21. Pediatric brain tumor cell lines. J Cell Biochem. 2015 Feb; 116(2):218-24. Xu J, Margol A, Asgharzadeh S, Erdreich-Epstein A. PMID: 25211508.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    22. Tumor-associated macrophages in SHH subgroup of medulloblastomas. Clin Cancer Res. 2015 Mar 15; 21(6):1457-65. Margol AS, Robison NJ, Gnanachandran J, Hung LT, Kennedy RJ, Vali M, Dhall G, Finlay JL, Erdreich-Epstein A, Krieger MD, Drissi R, Fouladi M, Gilles FH, Judkins AR, Sposto R, Asgharzadeh S. PMID: 25344580.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    23. Pathology and diagnosis of SMARCB1-deficient tumors. Cancer Genet. 2014 Sep; 207(9):358-64. Margol AS, Judkins AR. PMID: 25246033.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    24. PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas. Clin Cancer Res. 2014 Feb 15; 20(4):827-36. Erdreich-Epstein A, Robison N, Ren X, Zhou H, Xu J, Davidson TB, Schur M, Gilles FH, Ji L, Malvar J, Shackleford GM, Margol AS, Krieger MD, Judkins AR, Jones DT, Pfister SM, Kool M, Sposto R, Asgharzadeh S, Asgharazadeh S. PMID: 24300787.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    25. Medulloblastoma expresses CD1d and can be targeted for immunotherapy with NKT cells. Clin Immunol. 2013 Oct; 149(1):55-64. Liu D, Song L, Brawley VS, Robison N, Wei J, Gao X, Tian G, Margol A, Ahmed N, Asgharzadeh S, Metelitsa LS. PMID: 23891738.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    26. Pharmacokinetics and pharmacogenomics of once-daily raltegravir and atazanavir in healthy volunteers. Antimicrob Agents Chemother. 2010 Nov; 54(11):4619-25. Neely M, Decosterd L, Fayet A, Lee JS, Margol A, Kanani M, di Iulio J, von Schoen-Angerer T, Jelliffe R, Calmy A. PMID: 20823282.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
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