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Salvage therapies for first relapse of SHH medulloblastoma in early childhood. Neuro Oncol. 2025 Apr 04.
Erker C, Mynarek M, Simbozel M, Craig BT, Harrod VL, Cappellano AM, Cohen KJ, Lopez VS, Morales-La Madrid A, Cacciotti C, Baroni L, Salloum R, Margol AS, Michaiel G, Aguilera D, Mazewski CM, Kline CN, Finlay JL, Abdelbaki MS, Murray JC, Dorris K, Crooks B, Ginn KF, Amayiri N, Tippelt S, Fleischhack G, Tonn S, Gerber NU, Lassaletta A, Hansford JR, Khan S, Gilheeney SW, Hoffman LM, Zapotocky M, Larouche V, Shah S, Ramaswamy V, Gajjar A, Perreault S, Mueller S, Hukin J, Cheng S, Wang ZJ, Matheson K, Bailey S, Bouffet E, Clifford SC, Robinson G, Dufour C, Rutkowski S, Lafay-Cousin L. PMID: 40186336.
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PubMed Mentions: Fields:
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Targeted detection of sequence variants in cell-free DNA from cerebrospinal fluid in pediatric central nervous system tumors. Front Oncol. 2024; 14:1513073.
O'Halloran K, Crotty EE, Christodoulou E, Leary SE, Miller A, Paulson VA, Lockwood CM, Margol AS, Biegel JA. PMID: 39834946; PMCID: PMC11743934.
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PubMed Mentions:
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Low-Pass Whole Genome Sequencing of Cell-Free DNA from Cerebrospinal Fluid: A Focus on Pediatric Central Nervous System Tumors. Clin Chem. 2025 Jan 03; 71(1):87-96.
O'Halloran K, Christodoulou E, Paulson VA, Cole BL, Margol AS, Biegel JA, Leary SES, Lockwood CM, Crotty EE. PMID: 39749518.
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PubMed Mentions: Fields:
Translation:
Humans
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Immune checkpoint inhibitors and endocrinopathies in pediatric brain tumor patients. J Pediatr Endocrinol Metab. 2025 Jan 29; 38(1):58-64.
Westermann CR, Davidson TB, Waters K, Margol AS, Cheung CC. PMID: 39680426; PMCID: PMC11832116.
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PubMed Mentions: Fields:
Translation:
Humans
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A comparative analysis of IDH-mutant glioma in pediatric, young adult, and older adult patients. Neuro Oncol. 2024 Dec 05; 26(12):2364-2376.
Lim-Fat MJ, Cotter JA, Touat M, Vogelzang J, Sousa C, Pisano W, Geduldig J, Bhave V, Driver J, Kao PC, McGovern A, Ma C, Margol AS, Cole K, Smith A, Goldman S, Kaneva K, Truong A, Nazemi KJ, Wood MD, Wright KD, London WB, Warren KE, Wen PY, Bi WL, Alexandrescu S, Reardon DA, Ligon KL, Yeo KK. PMID: 39082676; PMCID: PMC11630535.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Pediatric Central Nervous System Embryonal Tumors: Presentation, Diagnosis, Therapeutic Strategies, and Survivorship-A Review. Pediatr Neurol. 2024 Dec; 161:237-246.
Ronsley R, Cole B, Ketterl T, Wright J, Ermoian R, Hoffman LM, Margol AS, Leary SES. PMID: 39447443.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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nnU-Net-based Segmentation of Tumor Subcompartments in Pediatric Medulloblastoma Using Multiparametric MRI: A Multi-institutional Study. Radiol Artif Intell. 2024 Sep; 6(5):e230115.
Bareja R, Ismail M, Martin D, Nayate A, Yadav I, Labbad M, Dullur P, Garg S, Tamrazi B, Salloum R, Margol A, Judkins A, Iyer S, de Blank P, Tiwari P. PMID: 39166971; PMCID: PMC11427926.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Effective re-induction regimen for children with recurrent medulloblastoma. Neurooncol Adv. 2024 Jan-Dec; 6(1):vdae070.
O'Halloran K, Phadnis S, Friedman GK, Metrock K, Davidson TB, Robison NJ, Tamrazi B, Cotter JA, Dhall G, Margol AS. PMID: 38863988; PMCID: PMC11165644.
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PubMed Mentions:
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Disease Evolution Monitored by Serial Cerebrospinal Fluid Liquid Biopsies in Two Cases of Recurrent Medulloblastoma. Int J Mol Sci. 2024 Apr 30; 25(9).
O'Halloran K, Margol A, Davidson TB, Estrine D, Tamrazi B, Cotter JA, Ji J, Biegel JA. PMID: 38732099; PMCID: PMC11084520.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study. Lancet Oncol. 2024 May; 25(5):668-682.
Ercan AB, Aronson M, Fernandez NR, Chang Y, Levine A, Liu ZA, Negm L, Edwards M, Bianchi V, Stengs L, Chung J, Al-Battashi A, Reschke A, Lion A, Ahmad A, Lassaletta A, Reddy AT, Al-Darraji AF, Shah AC, Van Damme A, Bendel A, Rashid A, Margol AS, Kelly BL, Pencheva B, Heald B, Lemieux-Anglin B, Crooks B, Koschmann C, Gilpin C, Porter CC, Gass D, Samuel D, Ziegler DS, Blumenthal DT, Kuo DJ, Hamideh D, Basel D, Khuong-Quang DA, Stearns D, Opocher E, Carceller F, Baris Feldman H, Toledano H, Winer I, Scheers I, Fedorakova I, Su JM, Vengoechea J, Sterba J, Knipstein J, Hansford JR, Gonzales-Santos JR, Bhatia K, Bielamowicz KJ, Minhas K, Nichols KE, Cole KA, Penney L, Hjort MA, Sabel M, Gil-da-Costa MJ, Murray MJ, Miller M, Blundell ML, Massimino M, Al-Hussaini M, Al-Jadiry MF, Comito MA, Osborn M, Link MP, Zapotocky M, Ghalibafian M, Shaheen N, Mushtaq N, Waespe N, Hijiya N, Fuentes-Bolanos N, Ahmad O, Chamdine O, Roy P, Pichurin PN, Nyman P, Pearlman R, Auer RC, Sukumaran RK, Kebudi R, Dvir R, Raphael R, Elhasid R, McGee RB, Chami R, Noss R, Tanaka R, Raskin S, Sen S, Lindhorst S, Perreault S, Caspi S, Riaz S, Constantini S, Albert S, Chaleff S, Bielack S, Chiaravalli S, Cramer SL, Roy S, Cahn S, Penna S, Hamid SA, Ghafoor T, Imam U, Larouche V, Magimairajan Issai V, Foulkes WD, Lee YY, Nathan PC, Maruvka YE, Greer MC, Durno C, Shlien A, Ertl-Wagner B, Villani A, Malkin D, Hawkins C, Bouffet E, Das A, Tabori U. PMID: 38552658.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Use of External Control Cohorts in Pediatric Brain Tumor Clinical Trials. J Clin Oncol. 2024 Apr 20; 42(12):1340-1343.
Margol AS, Molinaro AM, Onar-Thomas A, Resnick A, Hanson D, Kieran M, Mishra-Kalyani P, Rivera D, Barone A, Arons D, Meehan C, Prados M. PMID: 38394473.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Final report of the phase II NEXT/CNS-GCT-4 trial: GemPOx followed by marrow-ablative chemotherapy for recurrent intracranial germ cell tumors. Neurooncol Pract. 2024 Apr; 11(2):188-198.
Shatara M, Blue M, Stanek J, Liu YA, Prevedello DM, Giglio P, Puduvalli VK, Gardner SL, Allen JC, Wong KK, Nelson MD, Gilles FH, Adams RH, Pauly J, O'Halloran K, Margol AS, Dhall G, Finlay JL. PMID: 38496907; PMCID: PMC10940828.
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PubMed Mentions:
1
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Low-pass whole-genome and targeted sequencing of cell-free DNA from cerebrospinal fluid in pediatric patients with central nervous system tumors. Neurooncol Adv. 2023 Jan-Dec; 5(1):vdad077.
O'Halloran K, Yellapantula V, Christodoulou E, Ostrow D, Bootwalla M, Ji J, Cotter J, Chapman N, Chu J, Margol A, Krieger MD, Chiarelli PA, Gai X, Biegel JA. PMID: 37461402; PMCID: PMC10349915.
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PubMed Mentions:
6
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OpenPBTA: The Open Pediatric Brain Tumor Atlas. Cell Genom. 2023 Jul 12; 3(7):100340.
Shapiro JA, Gaonkar KS, Spielman SJ, Savonen CL, Bethell CJ, Jin R, Rathi KS, Zhu Y, Egolf LE, Farrow BK, Miller DP, Yang Y, Koganti T, Noureen N, Koptyra MP, Duong N, Santi M, Kim J, Robins S, Storm PB, Mack SC, Lilly JV, Xie HM, Jain P, Raman P, Rood BR, Lulla RR, Nazarian J, Kraya AA, Vaksman Z, Heath AP, Kline C, Scolaro L, Viaene AN, Huang X, Way GP, Foltz SM, Zhang B, Poetsch AR, Mueller S, Ennis BM, Prados M, Diskin SJ, Zheng S, Guo Y, Kannan S, Waanders AJ, Margol AS, Kim MC, Hanson D, Van Kuren N, Wong J, Kaufman RS, Coleman N, Blackden C, Cole KA, Mason JL, Madsen PJ, Koschmann CJ, Stewart DR, Wafula E, Brown MA, Resnick AC, Greene CS, Rokita JL, Taroni JN, Children’s Brain Tumor Network, Pacific Pediatric Neuro-Oncology Consortium. PMID: 37492101; PMCID: PMC10363844.
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PubMed Mentions:
22 Fields:
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Addendum: Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy. Oncotarget. 2023 May 19; 14:502.
Toll SA, Tran HN, Cotter J, Judkins AR, Tamrazi B, Biegel JA, Dhall G, Robison NJ, Waters K, Patel P, Cooper R, Margol AS. PMID: 37204254; PMCID: PMC10197959.
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PubMed Mentions: Fields:
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Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor. Neoplasia. 2023 03; 37:100880.
Alva E, Rubens J, Chi S, Rosenberg T, Reddy A, Raabe EH, Margol A. PMID: 36773516; PMCID: PMC9929860.
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PubMed Mentions:
11 Fields:
Translation:
HumansCTClinical Trials
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Multi-institutional study of the frequency, genomic landscape, and outcome of IDH-mutant glioma in pediatrics. Neuro Oncol. 2023 01 05; 25(1):199-210.
Yeo KK, Alexandrescu S, Cotter JA, Vogelzang J, Bhave V, Li MM, Ji J, Benhamida JK, Rosenblum MK, Bale TA, Bouvier N, Kaneva K, Rosenberg T, Lim-Fat MJ, Ghosh H, Martinez M, Aguilera D, Smith A, Goldman S, Diamond EL, Gavrilovic I, MacDonald TJ, Wood MD, Nazemi KJ, Truong A, Cluster A, Ligon KL, Cole K, Bi WL, Margol AS, Karajannis MA, Wright KD. PMID: 35604410; PMCID: PMC9825351.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study. J Clin Oncol. 2023 04 01; 41(10):1921-1932.
Erker C, Mynarek M, Bailey S, Mazewski CM, Baroni L, Massimino M, Hukin J, Aguilera D, Cappellano AM, Ramaswamy V, Lassaletta A, Perreault S, Kline CN, Rajagopal R, Michaiel G, Zapotocky M, Santa-Maria Lopez V, La Madrid AM, Cacciotti C, Sandler ES, Hoffman LM, Klawinski D, Khan S, Salloum R, Hoppmann AL, Larouche V, Dorris K, Toledano H, Gilheeney SW, Abdelbaki MS, Wilson B, Tsang DS, Knipstein J, Oren MY, Shah S, Murray JC, Ginn KF, Wang ZJ, Fleischhack G, Obrecht D, Tonn S, Harrod VL, Matheson K, Crooks B, Strother DR, Cohen KJ, Hansford JR, Mueller S, Margol A, Gajjar A, Dhall G, Finlay JL, Northcott PA, Rutkowski S, Clifford SC, Robinson G, Bouffet E, Lafay-Cousin L. PMID: 36548930.
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PubMed Mentions:
7 Fields:
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Novel MRI deformation-heterogeneity radiomic features are associated with molecular subgroups and overall survival in pediatric medulloblastoma: Preliminary findings from a multi-institutional study. Front Oncol. 2022; 12:915143.
Iyer S, Ismail M, Tamrazi B, Salloum R, de Blank P, Margol A, Correa R, Chen J, Bera K, Statsevych V, Ho ML, Vaidya P, Verma R, Hawes D, Judkins A, Fu P, Madabhushi A, Tiwari P. PMID: 36620600; PMCID: PMC9811390.
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PubMed Mentions:
5
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Upfront molecular targeted therapy for the treatment of BRAF-mutant pediatric high-grade glioma. Neuro Oncol. 2022 11 02; 24(11):1964-1975.
Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA. PMID: 35397478; PMCID: PMC9629451.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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MR multitasking-based dynamic imaging for cerebrovascular evaluation (MT-DICE): Simultaneous quantification of permeability and leakage-insensitive perfusion by dynamic T1/T2* mapping. Magn Reson Med. 2023 Jan; 89(1):161-176.
Hu Z, Christodoulou AG, Wang N, Xie Y, Shiroishi MS, Yang W, Zada G, Chow FE, Margol AS, Tamrazi B, Chang EL, Li D, Fan Z. PMID: 36128892; PMCID: PMC9826278.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Safety of Tumor Treating Fields (TTFields) therapy in pediatric patients with malignant brain tumors: Post-marketing surveillance data. Front Oncol. 2022; 12:958637.
Goldman S, Margol A, Hwang EI, Tanaka K, Suchorska B, Crawford JR, Kesari S. PMID: 36072789; PMCID: PMC9443515.
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PubMed Mentions:
7
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Multi-institutional analysis of central nervous system germ cell tumors in patients with Down syndrome. Pediatr Blood Cancer. 2022 10; 69(10):e29830.
Harris MK, Graham RT, Cappellano AM, Margol AS, Michaiel G, Crawford JR, Ioakeim-Ioannidou M, Stanek JR, Liu KX, MacDonald SM, Abdelbaki MS. PMID: 35686831.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Quantitative Nuclear Histomorphometry Predicts Molecular Subtype and Clinical Outcome in Medulloblastomas: Preliminary Findings. J Pathol Inform. 2022; 13:100090.
Whitney J, Dollinger L, Tamrazi B, Hawes D, Couce M, Marcheque J, Judkins A, Margol A, Madabhushi A. PMID: 36268104; PMCID: PMC9576985.
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PubMed Mentions:
1
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Primary Primitive Neuroectodermal Tumor of the Spine With t(11;22): Report of 3 Cases and Review of Literature. J Pediatr Hematol Oncol. 2021 Oct 01; 43(7):e983-e986.
Margol A, Abongwa C, Dhall G. PMID: 33480656.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Multi-institutional analysis of treatment modalities in basal ganglia and thalamic germinoma. Pediatr Blood Cancer. 2021 10; 68(10):e29172.
Graham RT, Abu-Arja MH, Stanek JR, Cappellano A, Coleman C, Chi S, Cooney T, Dhall G, Ellen JG, Finlay JL, Fisher MJ, Friedman GK, Gajjar A, Gauvain K, Hoffman LM, Hukin J, Lucas JT, Mueller S, Navalkele P, Ronsley R, Tinkle C, Villeneuve S, Yeo KK, Su JM, Margol A, Gottardo NG, Allen J, Packer R, Bartels U, Abdelbaki MS. PMID: 34125480; PMCID: PMC9639702.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature. Brain Pathol. 2021 07; 31(4):e12959.
Chang EK, Smith-Cohn MA, Tamrazi B, Ji J, Krieger M, Holdhoff M, Eberhart CG, Margol AS, Cotter JA. PMID: 33960568; PMCID: PMC8412065.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Clinical utility of comprehensive genomic profiling in central nervous system tumors of children and young adults. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab037.
Ji J, Kaneva K, Hiemenz MC, Dhall G, Davidson TB, Erdreich-Epstein A, Hawes D, Hurth K, Margol AS, Mathew AJ, Robison NJ, Schmidt RJ, Tran HN, Judkins AR, Cotter JA, Biegel JA. PMID: 33948563; PMCID: PMC8080244.
View in:
PubMed Mentions:
6
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Feasibility of Treating High Grade Gliomas in Children with Tumor-Treating Fields: A Case Series. Cureus. 2020 Oct 05; 12(10):e10804.
Crawford J, Saria MG, Dhall G, Margol A, Kesari S. PMID: 33163308; PMCID: PMC7641478.
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PubMed Mentions:
4
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Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumors. Neuro Oncol. 2020 07 07; 22(7):944-954.
Hoffman LM, Richardson EA, Ho B, Margol A, Reddy A, Lafay-Cousin L, Chi S, Slavc I, Judkins A, Hasselblatt M, Bourdeaut F, Frühwald MC, Vibhakar R, Bouffet E, Huang A. PMID: 32129445; PMCID: PMC7339881.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Central diabetes insipidus: A rare unreported side effect of temozolomide in pediatrics. Pediatr Blood Cancer. 2020 12; 67(12):e28516.
Kuo C, Foon D, Waters K, Cheung C, Margol AS. PMID: 32573959.
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PubMed Mentions:
2 Fields:
Translation:
Humans
-
SWI/SNF complex heterogeneity is related to polyphenotypic differentiation, prognosis, and immune response in rhabdoid tumors. Neuro Oncol. 2020 06 09; 22(6):785-796.
Panwalkar P, Pratt D, Chung C, Dang D, Le P, Martinez D, Bayliss JM, Smith KS, Adam M, Potter S, Northcott PA, Mascarenhas L, Shows J, Pawel B, Margol A, Huang A, Judkins AR, Venneti S. PMID: 31912158; PMCID: PMC7283032.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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A genome-wide association study on medulloblastoma. J Neurooncol. 2020 Apr; 147(2):309-315.
Dahlin AM, Wibom C, Andersson U, Bybjerg-Grauholm J, Deltour I, Hougaard DM, Scheurer ME, Lau CC, McKean-Cowdin R, Kennedy RJ, Hung LT, Yee J, Margol AS, Barrington-Trimis J, Gauderman WJ, Feychting M, Schüz J, Röösli M, Kjaerheim K, Cefalo Study Group, Januszkiewicz-Lewandowska D, Fichna M, Nowak J, Searles Nielsen S, Asgharzadeh S, Mirabello L, Hjalmars U, Melin B. PMID: 32056145; PMCID: PMC7136185.
View in:
PubMed Mentions:
5 Fields:
-
Primary diffuse leptomeningeal glioneuronal tumors of the central nervous system: Report of three cases and review of literature. Pediatr Hematol Oncol. 2020 Apr; 37(3):248-258.
Abongwa C, Cotter J, Tamrazi B, Dhall G, Davidson T, Margol A. PMID: 31951480.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
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Prognostic significance of molecular subgroups of medulloblastoma in young children receiving irradiation-sparing regimens. J Neurooncol. 2019 Nov; 145(2):375-383.
Yeo KK, Margol AS, Kennedy RJ, Hung L, Robison NJ, Dhall G, Asgharzadeh S. PMID: 31621042; PMCID: PMC7543681.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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Clinical and neuropsychological outcome of pediatric non-midline central nervous system germinoma treated with chemotherapy and reduced dose/volume irradiation: The Children's Hospital Los Angeles experience. Pediatr Blood Cancer. 2019 12; 66(12):e27983.
Yeo KK, Kayser K, Margol AS, Wong KK, Robison N, Finlay J, Dhall G. PMID: 31502379.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Pediatric Atypical Teratoid/Rhabdoid Tumors of the Brain: Identification of Metabolic Subgroups Using In Vivo 1H-MR Spectroscopy. AJNR Am J Neuroradiol. 2019 05; 40(5):872-877.
Tamrazi B, Venneti S, Margol A, Hawes D, Cen SY, Nelson M, Judkins A, Biegel J, Blüml S. PMID: 30948375; PMCID: PMC7053888.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
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Sustained response of three pediatric BRAFV600E mutated high-grade gliomas to combined BRAF and MEK inhibitor therapy. Oncotarget. 2019 Jan 11; 10(4):551-557.
Toll SA, Tran HN, Cotter J, Judkins AR, Tamrazi B, Biegel JA, Dhall G, Robison NJ, Waters K, Patel P, Cooper R, Margol AS. PMID: 30728904; PMCID: PMC6355184.
View in:
PubMed Mentions:
30 Fields:
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A comparative analysis of clinicopathological features and survival among early adolescents/young adults and children with low-grade glioma: a report from the Children's Oncology Group. J Neurooncol. 2018 Dec; 140(3):575-582.
Margol AS, Yeo KK, Xia C, Onar A, Robison NJ, Freyer DR, Dhall G. PMID: 30173409; PMCID: PMC6433163.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Transmission of a TP53 germline mutation from unaffected male carrier associated with pediatric glioblastoma in his child and gestational choriocarcinoma in his female partner. Cold Spring Harb Mol Case Stud. 2018 04; 4(2).
Cotter JA, Szymanski L, Karimov C, Boghossian L, Margol A, Dhall G, Tamrazi B, Varaprasathan GI, Parham DM, Judkins AR, Biegel JA. PMID: 29581140; PMCID: PMC5880265.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
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Phase I trial of dasatinib, lenalidomide, and temozolomide in children with relapsed or refractory central nervous system tumors. J Neurooncol. 2018 May; 138(1):199-207.
Robison NJ, Yeo KK, Berliner AP, Malvar J, Sheard MA, Margol AS, Seeger RC, Rushing T, Finlay JL, Sposto R, Dhall G. PMID: 29427149; PMCID: PMC5930136.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCellsCTClinical Trials
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Palliative Care Options for a Young Adult Patient with a Diffuse Intrinsic Pontine Glioma. Cureus. 2017 Aug 18; 9(8):e1580.
Sison J, Tran H, Margol A, Tiwari N, Garcia KM, Cotter J, Kiehna E, Olch AJ, Wong K. PMID: 29057192; PMCID: PMC5647135.
View in:
PubMed Mentions:
3
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Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome. Acta Neuropathol. 2017 11; 134(5):705-714.
Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C, Yip S, Hukin J, Sun Y, Schipper MJ, Chavez L, Margol A, Pekmezci M, Chung C, Banda A, Bayliss JM, Curry SJ, Santi M, Rodriguez FJ, Snuderl M, Karajannis MA, Saratsis AM, Horbinski CM, Carret AS, Wilson B, Johnston D, Lafay-Cousin L, Zelcer S, Eisenstat D, Silva M, Scheinemann K, Jabado N, McNeely PD, Kool M, Pfister SM, Taylor MD, Hawkins C, Korshunov A, Judkins AR, Venneti S. PMID: 28733933; PMCID: PMC5647236.
View in:
PubMed Mentions:
99 Fields:
Translation:
Humans
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Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach. J Neurooncol. 2017 05; 133(1):119-128.
Fay-McClymont TB, Ploetz DM, Mabbott D, Walsh K, Smith A, Chi SN, Wells E, Madden J, Margol A, Finlay J, Kieran MW, Strother D, Dhall G, Packer RJ, Foreman NK, Bouffet E, Lafay-Cousin L. PMID: 28405869.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
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Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Sci Transl Med. 2016 11 23; 8(366):366ra161.
Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari B, Margol AS, Panwalkar P, Parolia A, Pekmezci M, McEachin RC, Cieslik M, Tamrazi B, Garcia BA, La Rocca G, Santi M, Lewis PW, Hawkins C, Melnick A, David Allis C, Thompson CB, Chinnaiyan AM, Judkins AR, Venneti S. PMID: 27881822; PMCID: PMC5123566.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansCells
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Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy. Pediatr Blood Cancer. 2016 09; 63(9):1527-34.
Lafay-Cousin L, Smith A, Chi SN, Wells E, Madden J, Margol A, Ramaswamy V, Finlay J, Taylor MD, Dhall G, Strother D, Kieran MW, Foreman NK, Packer RJ, Bouffet E. PMID: 27145464; PMCID: PMC5031363.
View in:
PubMed Mentions:
44 Fields:
Translation:
Humans
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Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi Anemia. Front Oncol. 2015; 5:191.
Xu J, Margol AS, Shukla A, Ren X, Finlay JL, Krieger MD, Gilles FH, Couch FJ, Aziz M, Fung ET, Asgharzadeh S, Barrett MT, Erdreich-Epstein A. PMID: 26380221; PMCID: PMC4550790.
View in:
PubMed Mentions:
10
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Molecular subgroups of medulloblastoma identification using noninvasive magnetic resonance spectroscopy. Neuro Oncol. 2016 Jan; 18(1):126-31.
Blüml S, Margol AS, Sposto R, Kennedy RJ, Robison NJ, Vali M, Hung LT, Muthugounder S, Finlay JL, Erdreich-Epstein A, Gilles FH, Judkins AR, Krieger MD, Dhall G, Nelson MD, Asgharzadeh S. PMID: 26254476; PMCID: PMC4677409.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
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Achieving target voriconazole concentrations more accurately in children and adolescents. Antimicrob Agents Chemother. 2015; 59(6):3090-7.
Neely M, Margol A, Fu X, van Guilder M, Bayard D, Schumitzky A, Orbach R, Liu S, Louie S, Hope W. PMID: 25779580; PMCID: PMC4432122.
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23 Fields:
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CTClinical Trials
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PubMed Mentions:
30 Fields:
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HumansCells
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Tumor-associated macrophages in SHH subgroup of medulloblastomas. Clin Cancer Res. 2015 Mar 15; 21(6):1457-65.
Margol AS, Robison NJ, Gnanachandran J, Hung LT, Kennedy RJ, Vali M, Dhall G, Finlay JL, Erdreich-Epstein A, Krieger MD, Drissi R, Fouladi M, Gilles FH, Judkins AR, Sposto R, Asgharzadeh S. PMID: 25344580; PMCID: PMC7654723.
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66 Fields:
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HumansCells
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Pathology and diagnosis of SMARCB1-deficient tumors. Cancer Genet. 2014 Sep; 207(9):358-64.
Margol AS, Judkins AR. PMID: 25246033.
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32 Fields:
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Humans
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PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas. Clin Cancer Res. 2014 Feb 15; 20(4):827-36.
Erdreich-Epstein A, Robison N, Ren X, Zhou H, Xu J, Davidson TB, Schur M, Gilles FH, Ji L, Malvar J, Shackleford GM, Margol AS, Krieger MD, Judkins AR, Jones DT, Pfister SM, Kool M, Sposto R, Asgharzadeh S, Asgharazadeh S. PMID: 24300787; PMCID: PMC3962776.
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19 Fields:
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HumansCells
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Medulloblastoma expresses CD1d and can be targeted for immunotherapy with NKT cells. Clin Immunol. 2013 Oct; 149(1):55-64.
Liu D, Song L, Brawley VS, Robison N, Wei J, Gao X, Tian G, Margol A, Ahmed N, Asgharzadeh S, Metelitsa LS. PMID: 23891738; PMCID: PMC3809126.
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41 Fields:
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HumansAnimalsCells
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Pharmacokinetics and pharmacogenomics of once-daily raltegravir and atazanavir in healthy volunteers. Antimicrob Agents Chemother. 2010 Nov; 54(11):4619-25.
Neely M, Decosterd L, Fayet A, Lee JS, Margol A, Kanani M, di Iulio J, von Schoen-Angerer T, Jelliffe R, Calmy A. PMID: 20823282; PMCID: PMC2976128.
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15 Fields:
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Humans