Loading...

Robinder G. Khemani, MD

Title(s)Associate Professor of Clinical Pediatrics
AddressCHL Mail Stop 12
Off Campus
Los Angeles CA 90089
Phone+1 323 361 2557
vCardDownload vCard

    Collapse Overview 
    Collapse Overview
    Dr. Khemani is a Pediatric Intensive Care Physician and Clinical Researcher at the Children's Hospital Los Angeles. His major area of research interest involves using observational data to answer important clinical questions in the realm of pediatric critical care. This includes but is not limited to the creation and validation of quality indicators and severity of illness scores to develop objective criteria for comparing pediatric intensive care unit (PICU) outcomes internationally. This work involves both disease specific markers for certain subgroups of PICU patients, or global ICU populations. These findings will help target specific areas for quality improvement, and help evaluate new interventions and treatment modalities.

    He is also interested in pediatric mechanical ventilation, lung injury, and respiratory physiology, both translationally and at the bedside. He has specific interests in acute respiratory distress syndrome and upper airway obstruction: developing and validating minimally invasive pulmonary function techniques. Moreover, he uses his background in statistical modeling to examine the impact of different treatment regimens on cohorts of patients with specific respiratory disease such as upper airway obstruction, obstructive airways, hypoxemic respiratory failure, and acute lung injury.

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Design and Rationale for Common Data Elements for Clinical Research in Pediatric Critical Care Medicine. Pediatr Crit Care Med. 2020 11; 21(11):e1038-e1041. Ward SL, Flori HR, Bennett TD, Sapru A, Mourani PM, Thomas NJ, Khemani RG. PMID: 32639472.
      View in: PubMed   Mentions:    Fields:    
    2. Ventilator Liberation in the Pediatric ICU. Respir Care. 2020 Oct; 65(10):1601-1610. Newth CJ, Hotz JC, Khemani RG. PMID: 32973103.
      View in: PubMed   Mentions:    Fields:    
    3. Lung- and Diaphragm-Protective Ventilation. Am J Respir Crit Care Med. 2020 10 01; 202(7):950-961. Goligher EC, Dres M, Patel BK, Sahetya SK, Beitler JR, Telias I, Yoshida T, Vaporidi K, Grieco DL, Schepens T, Grasselli G, Spadaro S, Dianti J, Amato M, Bellani G, Demoule A, Fan E, Ferguson ND, Georgopoulos D, Guérin C, Khemani RG, Laghi F, Mercat A, Mojoli F, Ottenheijm CAC, Jaber S, Heunks L, Mancebo J, Mauri T, Pesenti A, Brochard L. PMID: 32516052.
      View in: PubMed   Mentions: 2     Fields:    
    4. Real-Time Effort Driven Ventilator Management: A Pilot Study. Pediatr Crit Care Med. 2020 Sep 24. Hotz JC, Bornstein D, Kohler K, Smith E, Suresh A, Klein M, Bhalla A, Newth CJ, Khemani RG. PMID: 32976348.
      View in: PubMed   Mentions:    Fields:    
    5. The Association Between Ventilatory Ratio and Mortality in Children and Young Adults. Respir Care. 2020 Aug 11. Bhalla AK, Dong J, Klein MJ, Khemani RG, Newth CJ. PMID: 32788320.
      View in: PubMed   Mentions:    Fields:    
    6. High Breath-by-Breath Variability Is Associated With Extubation Failure in Children. Crit Care Med. 2020 Aug; 48(8):1165-1174. Knox KE, Nava-Guerra L, Hotz JC, Newth CJL, Khoo MCK, Khemani RG. PMID: 32697487.
      View in: PubMed   Mentions:    Fields:    
    7. Thresholds for oximetry alarms and target range in the NICU: an observational assessment based on likely oxygen tension and maturity. BMC Pediatr. 2020 Jun 27; 20(1):317. Bachman TE, Iyer NP, Newth CJL, Ross PA, Khemani RG. PMID: 32593300.
      View in: PubMed   Mentions:    Fields:    
    8. Research and Quality Improvement Must Evolve With Changing Clinical Practice. Pediatr Crit Care Med. 2020 06; 21(6):587-588. Khemani RG. PMID: 32483022.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Early Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study. Am J Respir Crit Care Med. 2020 06 01; 201(11):1389-1397. Rowan CM, Klein MJ, Hsing DD, Dahmer MK, Spinella PC, Emeriaud G, Hassinger AB, Piñeres-Olave BE, Flori HR, Haileselassie B, Lopez-Fernandez YM, Chima RS, Shein SL, Maddux AB, Lillie J, Izquierdo L, Kneyber MCJ, Smith LS, Khemani RG, Thomas NJ, Yehya N. PMID: 32130867.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Predicting Mortality in Children With Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. Crit Care Med. 2020 06; 48(6):e514-e522. Yehya N, Harhay MO, Klein MJ, Shein SL, Piñeres-Olave BE, Izquierdo L, Sapru A, Emeriaud G, Spinella PC, Flori HR, Dahmer MK, Maddux AB, Lopez-Fernandez YM, Haileselassie B, Hsing DD, Chima RS, Hassinger AB, Valentine SL, Rowan CM, Kneyber MCJ, Smith LS, Khemani RG, Thomas NJ. PMID: 32271186.
      View in: PubMed   Mentions: 1     Fields:    
    11. Prognostic relevance and inter-observer reliability of chest-imaging in pediatric ARDS: a pediatric acute respiratory distress incidence and epidemiology (PARDIE) study. Intensive Care Med. 2020 Jul; 46(7):1382-1393. López-Fernández YM, Smith LS, Kohne JG, Weinman JP, Modesto-Alapont V, Reyes-Dominguez SB, Medina A, Piñeres-Olave BE, Mahieu N, Klein MJ, Flori HR, Jouvet P, Khemani RG. PMID: 32451578.
      View in: PubMed   Mentions:    Fields:    
    12. The role of computer-based clinical decision support systems to deliver protective mechanical ventilation. Curr Opin Crit Care. 2020 02; 26(1):73-81. Khemani RG, Hotz JC, Sward KA, Newth CJL. PMID: 31764194.
      View in: PubMed   Mentions:    Fields:    
    13. Neurally adjusted ventilatory assist mitigates ventilator-induced diaphragm injury in rabbits. Respir Res. 2019 Dec 23; 20(1):293. Shimatani T, Shime N, Nakamura T, Ohshimo S, Hotz J, Khemani RG. PMID: 31870367.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    14. A Phase II randomized controlled trial for lung and diaphragm protective ventilation (Real-time Effort Driven VENTilator management). Contemp Clin Trials. 2020 01; 88:105893. Khemani RG, Hotz JC, Klein MJ, Kwok J, Park C, Lane C, Smith E, Kohler K, Suresh A, Bornstein D, Elkunovich M, Ross PA, Deakers T, Beltramo F, Nelson L, Shah S, Bhalla A, Curley MAQ, Newth CJL. PMID: 31740425.
      View in: PubMed   Mentions:    Fields:    
    15. Definition and global epidemiology of pediatric acute respiratory distress syndrome. Ann Transl Med. 2019 Oct; 7(19):502. Beltramo F, Khemani RG. PMID: 31728355.
      View in: PubMed   Mentions:
    16. Age-Stratified Risk of Critical Illness in Young Children Presenting to the Emergency Department with Suspected Influenza. J Pediatr. 2019 12; 215:132-138.e2. Chaudhari PP, Monuteaux MC, Pannaraj PS, Khemani RG, Bachur RG. PMID: 31561954.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Risk Factors for Mortality and Pre-ICU Fluid Balance Among Critically Ill Hematopoietic Stem Cell Transplant Patients. J Intensive Care Med. 2020 Nov; 35(11):1265-1270. Mueller DM, Markovitz BP, Zinter MS, Takimoto SW, Khemani RG. PMID: 31185788.
      View in: PubMed   Mentions:    Fields:    
    18. Body Habitus and Risk of Mortality in Pediatric Sepsis and Septic Shock: A Retrospective Cohort Study. J Pediatr. 2019 07; 210:178-183.e2. Ross PA, Klein MJ, Nguyen T, Leung D, Khemani RG, Newth CJL, Bhalla AK. PMID: 31036411.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Minimal Change in Cardiac Index With Increasing PEEP in Pediatric Acute Respiratory Distress Syndrome. Front Pediatr. 2019; 7:9. Virk MK, Hotz JC, Wong W, Khemani RG, Newth CJL, Ross PA. PMID: 30761278.
      View in: PubMed   Mentions:
    20. Derivation and Validation of an Objective Effort of Breathing Score in Critically Ill Children. Pediatr Crit Care Med. 2019 01; 20(1):e15-e22. Shein SL, Hotz J, Khemani RG. PMID: 30395108.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. The authors reply. Crit Care Med. 2018 12; 46(12):e1231. Bhalla AK, Yehya N, Mack WJ, Wilson ML, Khemani RG, Newth CJL. PMID: 30444833.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    22. Pediatric Ventilator-Associated Events: Analysis of the Pediatric Ventilator-Associated Infection Data. Pediatr Crit Care Med. 2018 Dec; 19(12):e631-e636. Willson DF, Hall M, Beardsley A, Hoot M, Kirby A, Hays S, Erickson S, Truemper E, Khemani R. PMID: 30234739.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. Epidemiology of Cause of Death in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2018 11; 46(11):1811-1819. Dowell JC, Parvathaneni K, Thomas NJ, Khemani RG, Yehya N. PMID: 30095498.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    24. The Association Between Inhaled Nitric Oxide Treatment and ICU Mortality and 28-Day Ventilator-Free Days in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2018 11; 46(11):1803-1810. Bhalla AK, Yehya N, Mack WJ, Wilson ML, Khemani RG, Newth CJL. PMID: 30028363.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study. Lancet Respir Med. 2019 02; 7(2):115-128. Khemani RG, Smith L, Lopez-Fernandez YM, Kwok J, Morzov R, Klein MJ, Yehya N, Willson D, Kneyber MCJ, Lillie J, Fernandez A, Newth CJL, Jouvet P, Thomas NJ. PMID: 30361119.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    26. Accuracy of Transcutaneous Carbon Dioxide Levels in Comparison to Arterial Carbon Dioxide Levels in Critically Ill Children. Respir Care. 2019 Feb; 64(2):201-208. Bhalla AK, Khemani RG, Hotz JC, Morzov RP, Newth CJ. PMID: 30254042.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Reply to Tremlett and Kanthimathinathan and to Koopman and Kneyber. Am J Respir Crit Care Med. 2018 09 15; 198(6):823-824. Khemani RG, Parvathaneni K, Yehya N, Bhalla AK, Thomas NJ, Newth CJL. PMID: 29958000.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. The Therapeutic Index. Pediatr Crit Care Med. 2018 08; 19(8):775-776. Smith LS, Khemani RG. PMID: 30095712.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality. Am J Respir Crit Care Med. 2018 07 01; 198(1):77-89. Khemani RG, Parvathaneni K, Yehya N, Bhalla AK, Thomas NJ, Newth CJL. PMID: 29373802.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    30. Predicting Body Height in a Pediatric Intensive Care Unit Using Ulnar Length. Front Pediatr. 2018; 6:187. Rasouli MA, Newth CJL, Khemani RG, Ross PA. PMID: 30035103.
      View in: PubMed   Mentions:
    31. Hypoxemic and hyperoxemic likelihood in pulse oximetry ranges: NICU observational study. Arch Dis Child Fetal Neonatal Ed. 2019 May; 104(3):F274-F279. Bachman TE, Newth CJL, Iyer NP, Ross PA, Khemani RG. PMID: 29925540.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Does Size Matter When Calculating the "Correct" Tidal Volume for Pediatric Mechanical Ventilation?: A Hypothesis Based on FVC. Chest. 2018 07; 154(1):77-83. Kim GJ, Newth CJL, Khemani RG, Wong SL, Coates AL, Ross PA. PMID: 29684318.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    33. Risk Stratification Using Oxygenation in the First 24 Hours of Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2018 04; 46(4):619-624. Yehya N, Thomas NJ, Khemani RG. PMID: 29293150.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. The authors reply. Crit Care Med. 2017 12; 45(12):e1304-e1305. Khemani RG, Ross PA, Typpo K. PMID: 29149006.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. The Conflicting Paradigm of Ventilator-Associated Conditions. Pediatr Crit Care Med. 2017 11; 18(11):1078-1079. Khemani RG, Smith L. PMID: 29099453.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol? Pediatr Crit Care Med. 2017 Nov; 18(11):e521-e529. Newth CJL, Sward KA, Khemani RG, Page K, Meert KL, Carcillo JA, Shanley TP, Moler FW, Pollack MM, Dalton HJ, Wessel DL, Berger JT, Berg RA, Harrison RE, Holubkov R, Doctor A, Dean JM, Jenkins TL, Nicholson CE. PMID: 28930815.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Potential Acceptability of a Pediatric Ventilator Management Computer Protocol. Pediatr Crit Care Med. 2017 Nov; 18(11):1027-1034. Sward KA, Newth CJL, Khemani RG, Page K, Meert KL, Carcillo JA, Shanley TP, Moler FW, Pollack MM, Dalton HJ, Wessel DL, Berger JT, Berg RA, Harrison RE, Doctor A, Dean JM, Holobkov R, Jenkins TL, Nicholson CE. PMID: 28926488.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    38. Measurements Obtained From Esophageal Balloon Catheters Are Affected by the Esophageal Balloon Filling Volume in Children With ARDS. Respir Care. 2018 Feb; 63(2):177-186. Hotz JC, Sodetani CT, Van Steenbergen J, Khemani RG, Deakers TW, Newth CJ. PMID: 29089460.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    39. Mechanical Ventilation and Decision Support in Pediatric Intensive Care. Pediatr Clin North Am. 2017 10; 64(5):1057-1070. Newth CJL, Khemani RG, Jouvet PA, Sward KA. PMID: 28941535.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    40. Risk Factors for Pediatric Extubation Failure: The Importance of Respiratory Muscle Strength. Crit Care Med. 2017 Aug; 45(8):e798-e805. Khemani RG, Sekayan T, Hotz J, Flink RC, Rafferty GF, Iyer N, Newth CJL. PMID: 28437378.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    41. The Relationship between High Flow Nasal Cannula Flow Rate and Effort of Breathing in Children. J Pediatr. 2017 10; 189:66-71.e3. Weiler T, Kamerkar A, Hotz J, Ross PA, Newth CJL, Khemani RG. PMID: 28669609.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCTClinical Trials
    42. Volume and Pressure Delivery During Pediatric High-Frequency Oscillatory Ventilation. Pediatr Crit Care Med. 2017 Apr; 18(4):e189-e194. Wong R, Deakers T, Hotz J, Khemani RG, Ross PA, Newth CJ. PMID: 28212162.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    43. Comparison of Effort of Breathing for Infants on Nasal Modes of Respiratory Support. J Pediatr. 2017 06; 185:26-32.e3. Kamerkar A, Hotz J, Morzov R, Newth CJL, Ross PA, Khemani RG. PMID: 28366356.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    44. Change in Oxygen Consumption Following Inhalation of Albuterol in Comparison with Levalbuterol in Healthy Adult Volunteers. Lung. 2017 04; 195(2):233-239. Virk MK, Hotz J, Khemani RG, Newth CJ, Ross PA. PMID: 28210808.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Interpretable Deep Models for ICU Outcome Prediction. AMIA Annu Symp Proc. 2016; 2016:371-380. Che Z, Purushotham S, Khemani R, Liu Y. PMID: 28269832.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    46. Bayes to the Rescue: Continuous Positive Airway Pressure Has Less Mortality Than High-Flow Oxygen. Pediatr Crit Care Med. 2017 02; 18(2):e92-e99. Modesto I Alapont V, Khemani RG, Medina A, Del Villar Guerra P, Molina Cambra A. PMID: 28157810.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    47. The authors reply. Pediatr Crit Care Med. 2017 02; 18(2):204-205. Yehya N, Bhalla AK, Thomas NJ, Khemani RG. PMID: 28157806.
      View in: PubMed   Mentions:    Fields:    
    48. Pediatric Ventilator-Associated Infections: The Ventilator-Associated INfection Study. Pediatr Crit Care Med. 2017 01; 18(1):e24-e34. Willson DF, Hoot M, Khemani R, Carrol C, Kirby A, Schwarz A, Gedeit R, Nett ST, Erickson S, Flori H, Hays S, Hall M. PMID: 27828898.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    49. Evaluating the Performance of the Pediatric Acute Lung Injury Consensus Conference Definition of Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2017 01; 18(1):17-25. Parvathaneni K, Belani S, Leung D, Newth CJ, Khemani RG. PMID: 27673384.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    50. Cardiac output and systemic vascular resistance: Clinical assessment compared with a noninvasive objective measurement in children with shock. J Crit Care. 2017 06; 39:6-10. Razavi A, Newth CJL, Khemani RG, Beltramo F, Ross PA. PMID: 28088009.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    51. CPAP alone best estimates post-extubation effort during spontaneous breathing trials in children. Intensive Care Med. 2017 01; 43(1):150-151. Khemani RG, Newth CJ. PMID: 27742999.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. A Simple and Robust Bedside Model for Mortality Risk in Pediatric Patients With Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2016 10; 17(10):907-916. Spicer AC, Calfee CS, Zinter MS, Khemani RG, Lo VP, Alkhouli MF, Orwoll BE, Graciano AL, Boriosi JP, Howard JP, Flori HR, Matthay MA, Sapru A. PMID: 27487912.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    53. Letter to Editor: Reliability of the Ultrasound Cardiac Output Monitor for Pediatric Patients. Pediatr Cardiol. 2016 Aug; 37(6):1189-90. Beltramo F, Menteer J, Razavi A, Khemani RG, Szmuszkovicz J, Newth CJ, Ross PA. PMID: 27350277.
      View in: PubMed   Mentions:    Fields:    
    54. Pediatric extubation readiness tests should not use pressure support. Intensive Care Med. 2016 Aug; 42(8):1214-22. Khemani RG, Hotz J, Morzov R, Flink RC, Kamerkar A, LaFortune M, Rafferty GF, Ross PA, Newth CJ. PMID: 27318942.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    55. PICU Volume and Outcome: A Severity-Adjusted Analysis. Pediatr Crit Care Med. 2016 06; 17(6):483-9. Markovitz BP, Kukuyeva I, Soto-Campos G, Khemani RG. PMID: 26959348.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    56. Development of a Prediction Model of Early Acute Kidney Injury in Critically Ill Children Using Electronic Health Record Data. Pediatr Crit Care Med. 2016 06; 17(6):508-15. Sanchez-Pinto LN, Khemani RG. PMID: 27124567.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    57. The authors reply. Pediatr Crit Care Med. 2016 06; 17(6):582. Mandell I, Khemani RG. PMID: 27261658.
      View in: PubMed   Mentions:    Fields:    
    58. Reply to Letter to the Editor. Pediatr Cardiol. 2016 Mar; 37(3):619-20. Beltramo F, Menteer J, Razavi A, Khemani RG, Szmuszkovicz J, Newth CJ, Ross PA. PMID: 26987651.
      View in: PubMed   Mentions:    Fields:    
    59. Obesity and Mortality Risk in Critically Ill Children. Pediatrics. 2016 Mar; 137(3):e20152035. Ross PA, Newth CJ, Leung D, Wetzel RC, Khemani RG. PMID: 26908670.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    60. Recruitment Maneuvers to the Extreme. Respir Care. 2016 Feb; 61(2):260-1. Bhalla AK, Khemani R. PMID: 26796618.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Alveolar Dead Space Fraction Discriminates Mortality in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2016 Feb; 17(2):101-9. Yehya N, Bhalla AK, Thomas NJ, Khemani RG. PMID: 26669646.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    62. Evaluating Risk Factors for Pediatric Post-extubation Upper Airway Obstruction Using a Physiology-based Tool. Am J Respir Crit Care Med. 2016 Jan 15; 193(2):198-209. Khemani RG, Hotz J, Morzov R, Flink R, Kamerkar A, Ross PA, Newth CJ. PMID: 26389847.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    63. Procalcitonin to Detect Suspected Bacterial Infections in the PICU. Pediatr Crit Care Med. 2016 Jan; 17(1):e4-12. Mandell IM, Aghamohammadi S, Deakers T, Khemani RG. PMID: 26492060.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    64. The authors reply. Crit Care Med. 2016 Jan; 44(1):e52-3. Bhalla A, Newth C, Khemani R. PMID: 26672944.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    65. Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study. Crit Care. 2015 Dec 14; 19:435. Orwoll BE, Spicer AC, Zinter MS, Alkhouli MF, Khemani RG, Flori HR, Neuhaus JM, Calfee CS, Matthay MA, Sapru A. PMID: 26652251.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    66. Databases for Research in Pediatric Acute Respiratory Distress Syndrome. J Pediatr Intensive Care. 2016 Sep; 5(3):89-94. Khemani RG. PMID: 31110891.
      View in: PubMed   Mentions:
    67. Higher Dead Space Is Associated With Increased Mortality in Critically Ill Children. Crit Care Med. 2015 Nov; 43(11):2439-45. Bhalla AK, Belani S, Leung D, Newth CJ, Khemani RG. PMID: 26200768.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    68. Comparison of Tidal Volumes at the Endotracheal Tube and at the Ventilator. Pediatr Crit Care Med. 2015 Nov; 16(9):e324-31. Kim P, Salazar A, Ross PA, Newth CJ, Khemani RG. PMID: 26226341.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    69. The authors reply. Pediatr Crit Care Med. 2015 Nov; 16(9):899-900. Erickson S, Smith LS, Khemani RG, Willson DF, Jouvet P, Thomas NJ. PMID: 26536565.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    70. Association Between Progression and Improvement of Acute Kidney Injury and Mortality in Critically Ill Children. Pediatr Crit Care Med. 2015 Oct; 16(8):703-10. Sanchez-Pinto LN, Goldstein SL, Schneider JB, Khemani RG. PMID: 26132741.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    71. Validation of an Ultrasound Cardiac Output Monitor as a Bedside Tool for Pediatric Patients. Pediatr Cardiol. 2016 Jan; 37(1):177-83. Beltramo F, Menteer J, Razavi A, Khemani RG, Szmuszkovicz J, Newth CJ, Ross PA. PMID: 26364291.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    72. The authors reply. Pediatr Crit Care Med. 2015 Sep; 16(7):689-91. Smith LS, Khemani RG, Erickson S, Willson DF, Jouvet P, Thomas NJ. PMID: 26335127.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    73. Monitoring Dead Space in Mechanically Ventilated Children: Volumetric Capnography Versus Time-Based Capnography. Respir Care. 2015 Nov; 60(11):1548-55. Bhalla AK, Rubin S, Newth CJ, Ross P, Morzov R, Soto-Campos G, Khemani R. PMID: 26199451.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    74. Pediatric acute respiratory distress syndrome: definition, incidence, and epidemiology: proceedings from the Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2015 Jun; 16(5 Suppl 1):S23-40. Khemani RG, Smith LS, Zimmerman JJ, Erickson S. PMID: 26035358.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    75. Are we ready to accept the Berlin definition of acute respiratory distress syndrome for use in children? Crit Care Med. 2015 May; 43(5):1132-4. Khemani RG, Smith L. PMID: 25876111.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    76. Pulmonary function testing in infants with tetralogy of Fallot and absent pulmonary valve syndrome. Ann Pediatr Cardiol. 2015 May-Aug; 8(2):108-12. Salazar AM, Newth CC, Khemani RG, Jürg H, Ross PA. PMID: 26085760.
      View in: PubMed   Mentions:
    77. Virtualization of open-source secure web services to support data exchange in a pediatric critical care research network. J Am Med Inform Assoc. 2015 Nov; 22(6):1271-6. Frey LJ, Sward KA, Newth CJ, Khemani RG, Cryer ME, Thelen JL, Enriquez R, Shaoyu S, Pollack MM, Harrison RE, Meert KL, Berg RA, Wessel DL, Shanley TP, Dalton H, Carcillo J, Jenkins TL, Dean JM. PMID: 25796596.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    78. Elevated positive end-expiratory pressure decreases cardiac index in a rhesus monkey model. Front Pediatr. 2014; 2:134. Ross PA, Khemani RG, Rubin SS, Bhalla AK, Newth CJ. PMID: 25520944.
      View in: PubMed   Mentions:
    79. Respiratory inductance plethysmography calibration for pediatric upper airway obstruction: an animal model. Pediatr Res. 2015 Jan; 77(1-1):75-83. Khemani RG, Flink R, Hotz J, Ross PA, Ghuman A, Newth CJ. PMID: 25279987.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    80. Pulse oximetry vs. PaO2 metrics in mechanically ventilated children: Berlin definition of ARDS and mortality risk. Intensive Care Med. 2015 Jan; 41(1):94-102. Khemani RG, Rubin S, Belani S, Leung D, Erickson S, Smith LS, Zimmerman JJ, Newth CJ. PMID: 25231293.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    81. Algorithms to estimate PaCO2 and pH using noninvasive parameters for children with hypoxemic respiratory failure. Respir Care. 2014 Aug; 59(8):1248-57. Khemani RG, Celikkaya EB, Shelton CR, Kale D, Ross PA, Wetzel RC, Newth CJ. PMID: 24368862.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    82. Existing data analysis in pediatric critical care research. Front Pediatr. 2014; 2:79. Bennett TD, Spaeder MC, Matos RI, Watson RS, Typpo KV, Khemani RG, Crow S, Benneyworth BD, Thiagarajan RR, Dean JM, Markovitz BP. PMID: 25121079.
      View in: PubMed   Mentions:
    83. Effort of breathing in children receiving high-flow nasal cannula. Pediatr Crit Care Med. 2014 Jan; 15(1):1-6. Rubin S, Ghuman A, Deakers T, Khemani R, Ross P, Newth CJ. PMID: 24201859.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    84. Impact of positive end-expiratory pressure on cardiac index measured by ultrasound cardiac output monitor*. Pediatr Crit Care Med. 2014 Jan; 15(1):15-20. Ingaramo OA, Ngo T, Khemani RG, Newth CJ. PMID: 24389709.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    85. Accuracy of pulse oximetry in children. Pediatrics. 2014 Jan; 133(1):22-9. Ross PA, Newth CJ, Khemani RG. PMID: 24344108.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    86. Evaluating the Berlin Definition in pediatric ARDS. Intensive Care Med. 2013 Dec; 39(12):2213-6. Khemani RG, Wilson DF, Esteban A, Ferguson ND. PMID: 24100944.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    87. Is shock index associated with outcome in children with sepsis/septic shock?*. Pediatr Crit Care Med. 2013 Oct; 14(8):e372-9. Yasaka Y, Khemani RG, Markovitz BP. PMID: 23962830.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    88. Impact of gender on sepsis mortality and severity of illness for prepubertal and postpubertal children. J Pediatr. 2013 Sep; 163(3):835-40.e1. Ghuman AK, Newth CJ, Khemani RG. PMID: 23706357.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    89. Patient origin is associated with duration of endotracheal intubation and PICU length of stay for children with status asthmaticus. J Intensive Care Med. 2014 May-Jun; 29(3):154-9. Shibata S, Khemani RG, Markovitz B. PMID: 23753230.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    90. Pediatric upper airway obstruction: interobserver variability is the road to perdition. J Crit Care. 2013 Aug; 28(4):490-7. Khemani RG, Schneider JB, Morzov R, Markovitz B, Newth CJ. PMID: 23337481.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    91. Dead space to tidal volume ratio (VD/VT) to explain extubation failure in children: the limitations of current evidence. J Pediatr (Rio J). 2012 May; 88(3):191-4. Khemani RG. PMID: 22718284.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    92. Pediatric rheumatic disease in the intensive care unit: lessons learned from 15 years of experience in a tertiary care pediatric hospital. Pediatr Crit Care Med. 2012 May; 13(3):e181-6. Radhakrishna SM, Reiff AO, Marzan KA, Azen C, Khemani RG, Rubin S, Menteer J, Brown DE, Shaham B. PMID: 22561277.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    93. Comparison of SpO2 to PaO2 based markers of lung disease severity for children with acute lung injury. Crit Care Med. 2012 Apr; 40(4):1309-16. Khemani RG, Thomas NJ, Venkatachalam V, Scimeme JP, Berutti T, Schneider JB, Ross PA, Willson DF, Hall MW, Newth CJ. PMID: 22202709.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    94. Effect of race on the timing of the Glenn and Fontan procedures for single-ventricle congenital heart disease. Pediatr Crit Care Med. 2012 Mar; 13(2):174-7. Ingaramo OA, Khemani RG, Markovitz BP, Epstein D. PMID: 21666532.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    95. The association between the end tidal alveolar dead space fraction and mortality in pediatric acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2012 Jan; 13(1):11-5. Ghuman AK, Newth CJ, Khemani RG. PMID: 21499169.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    96. Variability in usual care mechanical ventilation for pediatric acute lung injury: the potential benefit of a lung protective computer protocol. Intensive Care Med. 2011 Nov; 37(11):1840-8. Khemani RG, Sward K, Morris A, Dean JM, Newth CJ. PMID: 21965099.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    97. Continuous infusion of bupivacaine reduces postoperative morphine use in adolescent idiopathic scoliosis after posterior spine fusion. Spine (Phila Pa 1976). 2011 Aug 15; 36(18):1478-83. Ross PA, Smith BM, Tolo VT, Khemani RG. PMID: 20881514.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    98. Race/Ethnicity is not associated with mortality in the PICU. Pediatrics. 2011 Mar; 127(3):e588-97. Epstein D, Wong CF, Khemani RG, Moromisato DY, Waters K, Kipke MD, Markovitz BP. PMID: 21357333.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    99. The design of future pediatric mechanical ventilation trials for acute lung injury. Am J Respir Crit Care Med. 2010 Dec 15; 182(12):1465-74. Khemani RG, Newth CJ. PMID: 20732987.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    100. Pressure-rate product and phase angle as measures of acute inspiratory upper airway obstruction in rhesus monkeys. Pediatr Pulmonol. 2010 Jul; 45(7):639-44. Ross PA, Hammer J, Khemani R, Klein M, Newth CJ. PMID: 20575087.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    101. Children with corrected or palliated congenital heart disease on home mechanical ventilation. Pediatr Pulmonol. 2010 Jul; 45(7):645-9. Edwards JD, Kun SS, Keens TG, Khemani RG, Moromisato DY. PMID: 20575088.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    102. Reducing the incidence of necrotizing enterocolitis in neonates with hypoplastic left heart syndrome with the introduction of an enteral feed protocol. Pediatr Crit Care Med. 2010 May; 11(3):373-7. del Castillo SL, McCulley ME, Khemani RG, Jeffries HE, Thomas DW, Peregrine J, Wells WJ, Starnes VA, Moromisato DY. PMID: 19838139.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    103. Post extubation stridor the call for objectivity. Indian Pediatr. 2010 Apr; 47(4):307-8. Khemani RG. PMID: 20431158.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    104. Steroids for post extubation stridor: pediatric evidence is still inconclusive. Intensive Care Med. 2010 Jul; 36(7):1276-7. Khemani RG, Randolph A, Markovitz B. PMID: 20237767.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    105. Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit. Crit Care Med. 2010 Mar; 38(3):933-9. Schneider J, Khemani R, Grushkin C, Bart R. PMID: 20124891.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    106. Outcome analysis of neonates with congenital diaphragmatic hernia treated with venovenous vs venoarterial extracorporeal membrane oxygenation. J Pediatr Surg. 2009 Sep; 44(9):1691-701. Guner YS, Khemani RG, Qureshi FG, Wee CP, Austin MT, Dorey F, Rycus PT, Ford HR, Friedlich P, Stein JE. PMID: 19735810.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    107. Can the Kawashima procedure be performed in younger patients? Ann Thorac Surg. 2009 Aug; 88(2):581-6; discussion 586-7. Nath DS, Carden AJ, Nussbaum DP, Shin AJ, Khemani RG, Starnes VA, Wells WJ. PMID: 19632416.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    108. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev. 2009 Jul 08; (3):CD001000. Khemani RG, Randolph A, Markovitz B. PMID: 19588321.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    109. Thoracic duct ligation for persistent chylothorax after pediatric cardiothoracic surgery. Ann Thorac Surg. 2009 Jul; 88(1):246-51; discussion 251-2. Nath DS, Savla J, Khemani RG, Nussbaum DP, Greene CL, Wells WJ. PMID: 19559234.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    110. Characteristics of children intubated and mechanically ventilated in 16 PICUs. Chest. 2009 Sep; 136(3):765-771. Khemani RG, Markovitz BP, Curley MAQ. PMID: 19542258.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    111. Effect of tidal volume in children with acute hypoxemic respiratory failure. Intensive Care Med. 2009 Aug; 35(8):1428-37. Khemani RG, Conti D, Alonzo TA, Bart RD, Newth CJ. PMID: 19533092.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    112. Comparison of the pulse oximetric saturation/fraction of inspired oxygen ratio and the PaO2/fraction of inspired oxygen ratio in children. Chest. 2009 Mar; 135(3):662-668. Khemani RG, Patel NR, Bart RD, Newth CJL. PMID: 19029434.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    113. Disseminated intravascular coagulation score is associated with mortality for children with shock. Intensive Care Med. 2009 Feb; 35(2):327-33. Khemani RG, Bart RD, Alonzo TA, Hatzakis G, Hallam D, Newth CJ. PMID: 18802683.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    114. Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. Cochrane Database Syst Rev. 2008 Apr 16; (2):CD001000. Markovitz BP, Randolph AG, Khemani RG. PMID: 18425866.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans