Anoopindar Bhalla • USC Profiles

Anoopindar K. Bhalla, MD

Title(s)	Associate Professor of Clinical Pediatrics
School	Keck School of Medicine of Usc
Address	CHL Mail Stop 12 Off Campus Los Angeles CA 90089
Phone	+1 323 361 2557
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selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Randomized Trial of Lung and Diaphragm Protective Ventilation in Children. NEJM Evid. 2025 Jun; 4(6):EVIDoa2400360. Khemani RG, Bhalla A, Hotz JC, Klein MJ, Kwok J, Kohler K, Bornstein D, Chang D, Armenta-Quiroz A, Vu K, Smith E, Suresh A, Baron D, Bonilla-Cartagena J, Ross PA, Deakers T, Beltramo F, Nelson L, Shah S, Elkunovich M, Curley MAQ, Mack W, Newth CJL. PMID: 40423397.

View in: PubMed Mentions: Fields:
Med Medicine (General)
Translation:CTClinical Trials
Mechanical Power in Decelerating Flow versus Square Flow Ventilation in Pediatric Acute Respiratory Distress Syndrome. Anesthesiology. 2024 Dec 01; 141(6):1095-1104. Percy AG, Keim G, Bhalla AK, Yehya N. PMID: 39190682; PMCID: PMC11560697.

View in: PubMed Mentions: Fields:
Ane Anesthesiology
Translation:Humans
Association of extreme hyperoxemic events and mortality in pediatric critical care: an observational cohort study. Front Pediatr. 2024; 12:1429882. Bachman TE, Newth CJL, Ross PA, Patel N, Bhalla A. PMID: 39144469; PMCID: PMC11322569.

View in: PubMed Mentions:
Noninvasive Surrogate for Physiologic Dead Space Using the Carbon Dioxide Ventilatory Equivalent: Testing in a Single-Center Cohort, 2017-2023. Pediatr Crit Care Med. 2024 Sep 01; 25(9):784-794. Bhalla AK, Klein MJ, Hotz J, Kwok J, Bonilla-Cartagena JE, Baron DA, Kohler K, Bornstein D, Chang D, Vu K, Armenta-Quiroz A, Nelson LP, Newth CJL, Khemani RG. PMID: 38771137; PMCID: PMC11379541.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Association between Age and Mortality in Pediatric and Adult Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2024 04 01; 209(7):871-878. Patel BM, Reilly JP, Bhalla AK, Smith LS, Khemani RG, Jones TK, Meyer NJ, Harhay MO, Yehya N. PMID: 38306669; PMCID: PMC10995578.

View in: PubMed Mentions: 8 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans
Immunocompromised-Associated Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study. Pediatr Crit Care Med. 2024 Apr 01; 25(4):288-300. Gertz SJ, Bhalla A, Chima RS, Emeriaud G, Fitzgerald JC, Hsing DD, Jeyapalan AS, Pike F, Sallee CJ, Thomas NJ, Yehya N, Rowan CM, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) Investigators and . PMID: 38236083; PMCID: PMC10994753.

View in: PubMed Mentions: 1 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Estimation of inspiratory effort using airway occlusion maneuvers in ventilated children: a secondary analysis of an ongoing randomized trial testing a lung and diaphragm protective ventilation strategy. Crit Care. 2023 11 29; 27(1):466. Ito Y, Herrera MG, Hotz JC, Kyogoku M, Newth CJL, Bhalla AK, Takeuchi M, Khemani RG. PMID: 38031116; PMCID: PMC10685539.

View in: PubMed Mentions: 4 Fields:
Cri Critical Care
Translation:Humans
Association Between COVID-19 and Severity of Illness for Children With Hyperglycemic Crisis. Hosp Pediatr. 2023 09 01; 13(9):794-801. Toomey V, Klein MJ, Vidmar AP, Chao LC, Pineda J, Bhalla A. PMID: 37539478.

View in: PubMed Mentions: 1 Fields:
Ped Pediatrics
Translation:Humans Cells PHPublic Health
Noninvasive Ventilation for Pediatric Acute Respiratory Distress Syndrome: Experience From the 2016/2017 Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Prospective Cohort Study. Pediatr Crit Care Med. 2023 09 01; 24(9):715-726. Emeriaud G, Pons-Òdena M, Bhalla AK, Shein SL, Killien EY, Modesto I Alapont V, Rowan C, Baudin F, Lin JC, Grégoire G, Napolitano N, Mayordomo-Colunga J, Diaz F, Cruces P, Medina A, Smith L, Khemani RG, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) Investigators and . PMID: 37255352; PMCID: PMC10524424.

View in: PubMed Mentions: 3 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Mechanical Power Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2023 Jul 01; 24(7):e307-e316. Percy AG, Mai MV, Bhalla AK, Yehya N. PMID: 36883840; PMCID: PMC10329976.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
The end-tidal alveolar dead space fraction for risk stratification during the first week of invasive mechanical ventilation: an observational cohort study. Crit Care. 2023 02 09; 27(1):54. Bhalla AK, Chau A, Khemani RG, Newth CJL. PMID: 36759925; PMCID: PMC9912669.

View in: PubMed Mentions: 4 Fields:
Cri Critical Care
Translation:Humans
Monitoring in Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2023 02 01; 24(12 Suppl 2):S112-S123. Bhalla A, Baudin F, Takeuchi M, Cruces P, Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) of the Pediatric Acute Lung Injur. PMID: 36661440; PMCID: PMC9980912.

View in: PubMed Mentions: 4 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2). Pediatr Crit Care Med. 2023 02 01; 24(2):143-168. Emeriaud G, López-Fernández YM, Iyer NP, Bembea MM, Agulnik A, Barbaro RP, Baudin F, Bhalla A, Brunow de Carvalho W, Carroll CL, Cheifetz IM, Chisti MJ, Cruces P, Curley MAQ, Dahmer MK, Dalton HJ, Erickson SJ, Essouri S, Fernández A, Flori HR, Grunwell JR, Jouvet P, Killien EY, Kneyber MCJ, Kudchadkar SR, Korang SK, Lee JH, Macrae DJ, Maddux A, Modesto I Alapont V, Morrow BM, Nadkarni VM, Napolitano N, Newth CJL, Pons-Odena M, Quasney MW, Rajapreyar P, Rambaud J, Randolph AG, Rimensberger P, Rowan CM, Sanchez-Pinto LN, Sapru A, Sauthier M, Shein SL, Smith LS, Steffen K, Takeuchi M, Thomas NJ, Tse SM, Valentine S, Ward S, Watson RS, Yehya N, Zimmerman JJ, Khemani RG, Second Pediatric Acute Lung Injury Consensus Conference (PALICC-2) Group on behalf of the Pediatric . PMID: 36661420; PMCID: PMC9848214.

View in: PubMed Mentions: 54 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Understanding clinical and biological heterogeneity to advance precision medicine in paediatric acute respiratory distress syndrome. Lancet Respir Med. 2023 02; 11(2):197-212. Kneyber MCJ, Khemani RG, Bhalla A, Blokpoel RGT, Cruces P, Dahmer MK, Emeriaud G, Grunwell J, Ilia S, Katira BH, Lopez-Fernandez YM, Rajapreyar P, Sanchez-Pinto LN, Rimensberger PC. PMID: 36566767; PMCID: PMC10880453.

View in: PubMed Mentions: 7 Fields:
Pul Pulmonary Medicine
Translation:Humans
Challenges Remain to Assess Post-ICU Morbidity and Identify Attributable Risk in Children With Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2022 07 01; 23(7):571-573. Bhalla AK, Khemani RG. PMID: 35797575; PMCID: PMC9473307.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Normalization to Predicted Body Weight May Underestimate Mechanical Energy in Pediatric Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2022 06 01; 205(11):1360-1363. Ito Y, Takeuchi M, Inata Y, Kyogoku M, Hotz JC, Bhalla AK, Newth CJL, Khemani RG. PMID: 35315733; PMCID: PMC9873119.

View in: PubMed Mentions: 1 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans
The Kids Are Not Okay: Healthcare Utilization After Critical Illness. Pediatr Crit Care Med. 2022 04 01; 23(4):334-337. Bhalla A. PMID: 35485499; PMCID: PMC9060346.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Epidemiology and Outcomes of Critically Ill Children at Risk for Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. Crit Care Med. 2022 03 01; 50(3):363-374. Shein SL, Maddux AB, Klein MJ, Bhalla A, Briassoulis G, Dahmer MK, Emeriaud G, Flori HR, Gedeit R, Ilia S, Kneyber MCJ, Napolitano N, Ohshimo S, Pons-Òdena M, Rubin S, White BR, Yehya N, Khemani R, Smith L, V4 PARDIE Investigators and the PALISI Network. PMID: 34582416.

View in: PubMed Mentions: 4 Fields:
Cri Critical Care
Translation:Humans
Mechanical power in pediatric acute respiratory distress syndrome: a PARDIE study. Crit Care. 2022 01 03; 26(1):2. Bhalla AK, Klein MJ, Modesto I Alapont V, Emeriaud G, Kneyber MCJ, Medina A, Cruces P, Diaz F, Takeuchi M, Maddux AB, Mourani PM, Camilo C, White BR, Yehya N, Pappachan J, Di Nardo M, Shein S, Newth C, Khemani R, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. PMID: 34980228; PMCID: PMC8722295.

View in: PubMed Mentions: 10 Fields:
Cri Critical Care
Translation:Humans
Beyond the Alveolar Epithelium: Plasma Soluble Receptor for Advanced Glycation End Products Is Associated With Oxygenation Impairment, Mortality, and Extrapulmonary Organ Failure in Children With Acute Respiratory Distress Syndrome. Crit Care Med. 2022 05 01; 50(5):837-847. Lim MJ, Zinter MS, Chen L, Wong KMY, Bhalla A, Gala K, Guglielmo M, Alkhouli M, Huard LL, Hanudel MR, Vangala S, Schwingshackl A, Matthay M, Sapru A. PMID: 34678846; PMCID: PMC9035468.

View in: PubMed Mentions: 6 Fields:
Cri Critical Care
Translation:Humans
Adherence to Lung-Protective Ventilation Principles in Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study. Crit Care Med. 2021 10 01; 49(10):1779-1789. Bhalla AK, Klein MJ, Emeriaud G, Lopez-Fernandez YM, Napolitano N, Fernandez A, Al-Subu AM, Gedeit R, Shein SL, Nofziger R, Hsing DD, Briassoulis G, Ilia S, Baudin F, Piñeres-Olave BE, Maria Izquierdo L, Lin JC, Cheifetz IM, Kneyber MCJ, Smith L, Khemani RG, Newth CJL, Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE) V.2. Investigators. PMID: 34259438; PMCID: PMC8448899.

View in: PubMed Mentions: 8 Fields:
Cri Critical Care
Translation:Humans
Questions About Fluid Management in Pediatric Acute Respiratory Distress Syndrome and the Design of Clinical Trials. Pediatr Crit Care Med. 2021 09 01; 22(9):847-849. Bhalla A, Khemani RG. PMID: 34473130; PMCID: PMC8475727.

View in: PubMed Mentions: 1 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
Declining Procedures in Pediatric Critical Care Medicine Using a National Database. Crit Care Explor. 2021 Mar; 3(3):e0359. Ross PA, Engorn BM, Newth CJL, Gordon C, Soto-Campos G, Bhalla AK. PMID: 33786435; PMCID: PMC7994033.

View in: PubMed Mentions: 3
Refining the Syndrome. Pediatr Crit Care Med. 2020 12; 21(12):1094-1096. Smith LS, Bhalla A, Yehya N. PMID: 33278219; PMCID: PMC7725435.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Real-Time Effort Driven Ventilator Management: A Pilot Study. Pediatr Crit Care Med. 2020 11; 21(11):933-940. Hotz JC, Bornstein D, Kohler K, Smith E, Suresh A, Klein M, Bhalla A, Newth CJ, Khemani RG. PMID: 32976348; PMCID: PMC7609612.

View in: PubMed Mentions: 6 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
The Association Between Ventilatory Ratio and Mortality in Children and Young Adults. Respir Care. 2021 Feb; 66(2):205-212. Bhalla AK, Dong J, Klein MJ, Khemani RG, Newth CJ. PMID: 32788320.

View in: PubMed Mentions: 5 Fields:
Pul Pulmonary Medicine
Translation:Humans
A Phase II randomized controlled trial for lung and diaphragm protective ventilation (Real-time Effort Driven VENTilator management). Contemp Clin Trials. 2020 01; 88:105893. Khemani RG, Hotz JC, Klein MJ, Kwok J, Park C, Lane C, Smith E, Kohler K, Suresh A, Bornstein D, Elkunovich M, Ross PA, Deakers T, Beltramo F, Nelson L, Shah S, Bhalla A, Curley MAQ, Newth CJL. PMID: 31740425; PMCID: PMC6952541.

View in: PubMed Mentions: 11 Fields:
Med Medicine (General)The Therapeutics
Translation:Humans CTClinical Trials
Timing of tracheostomy placement among children with severe traumatic brain injury: A propensity-matched analysis. J Trauma Acute Care Surg. 2019 10; 87(4):818-826. McLaughlin C, Darcy D, Park C, Lane CJ, Mack WJ, Bliss DW, Bhalla A, Upperman JS, Nathens AB, Burd RS, Jensen AR. PMID: 30882764; PMCID: PMC6744364.

View in: PubMed Mentions: 6 Fields:
Gen General Surgery Tra Traumatology
Translation:Humans
Reply. J Pediatr. 2019 10; 213:248-249. Ross PA, Bhalla AK. PMID: 31307760.

View in: PubMed Mentions: Fields:
Ped Pediatrics
Translation:Humans
Body Habitus and Risk of Mortality in Pediatric Sepsis and Septic Shock: A Retrospective Cohort Study. J Pediatr. 2019 07; 210:178-183.e2. Ross PA, Klein MJ, Nguyen T, Leung D, Khemani RG, Newth CJL, Bhalla AK. PMID: 31036411.

View in: PubMed Mentions: 10 Fields:
Ped Pediatrics
Translation:Humans
The authors reply. Crit Care Med. 2018 12; 46(12):e1231. Bhalla AK, Yehya N, Mack WJ, Wilson ML, Khemani RG, Newth CJL. PMID: 30444833; PMCID: PMC7182096.

View in: PubMed Mentions: Fields:
Cri Critical Care
Translation:Humans
The Association Between Inhaled Nitric Oxide Treatment and ICU Mortality and 28-Day Ventilator-Free Days in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2018 11; 46(11):1803-1810. Bhalla AK, Yehya N, Mack WJ, Wilson ML, Khemani RG, Newth CJL. PMID: 30028363; PMCID: PMC6185752.

View in: PubMed Mentions: 5 Fields:
Cri Critical Care
Translation:Humans
Accuracy of Transcutaneous Carbon Dioxide Levels in Comparison to Arterial Carbon Dioxide Levels in Critically Ill Children. Respir Care. 2019 Feb; 64(2):201-208. Bhalla AK, Khemani RG, Hotz JC, Morzov RP, Newth CJ. PMID: 30254042.

View in: PubMed Mentions: 4 Fields:
Pul Pulmonary Medicine
Translation:Humans
Reply to Tremlett and Kanthimathinathan and to Koopman and Kneyber. Am J Respir Crit Care Med. 2018 09 15; 198(6):823-824. Khemani RG, Parvathaneni K, Yehya N, Bhalla AK, Thomas NJ, Newth CJL. PMID: 29958000; PMCID: PMC6835070.

View in: PubMed Mentions: Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans
Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality. Am J Respir Crit Care Med. 2018 07 01; 198(1):77-89. Khemani RG, Parvathaneni K, Yehya N, Bhalla AK, Thomas NJ, Newth CJL. PMID: 29373802; PMCID: PMC6034123.

View in: PubMed Mentions: 49 Fields:
Cri Critical Care Pul Pulmonary Medicine
Translation:Humans
The authors reply. Pediatr Crit Care Med. 2017 02; 18(2):204-205. Yehya N, Bhalla AK, Thomas NJ, Khemani RG. PMID: 28157806.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Recruitment Maneuvers to the Extreme. Respir Care. 2016 Feb; 61(2):260-1. Bhalla AK, Khemani R. PMID: 26796618.

View in: PubMed Mentions: 1 Fields:
Pul Pulmonary Medicine
Translation:Humans
Alveolar Dead Space Fraction Discriminates Mortality in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2016 Feb; 17(2):101-9. Yehya N, Bhalla AK, Thomas NJ, Khemani RG. PMID: 26669646; PMCID: PMC4740261.

View in: PubMed Mentions: 15 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
The authors reply. Crit Care Med. 2016 Jan; 44(1):e52-3. Bhalla A, Newth C, Khemani R. PMID: 26672944.

View in: PubMed Mentions: Fields:
Cri Critical Care
Translation:Humans
Higher Dead Space Is Associated With Increased Mortality in Critically Ill Children. Crit Care Med. 2015 Nov; 43(11):2439-45. Bhalla AK, Belani S, Leung D, Newth CJ, Khemani RG. PMID: 26200768.

View in: PubMed Mentions: 9 Fields:
Cri Critical Care
Translation:Humans
Monitoring Dead Space in Mechanically Ventilated Children: Volumetric Capnography Versus Time-Based Capnography. Respir Care. 2015 Nov; 60(11):1548-55. Bhalla AK, Rubin S, Newth CJ, Ross P, Morzov R, Soto-Campos G, Khemani R. PMID: 26199451.

View in: PubMed Mentions: 11 Fields:
Pul Pulmonary Medicine
Translation:Humans
Elevated positive end-expiratory pressure decreases cardiac index in a rhesus monkey model. Front Pediatr. 2014; 2:134. Ross PA, Khemani RG, Rubin SS, Bhalla AK, Newth CJ. PMID: 25520944; PMCID: PMC4253666.

View in: PubMed Mentions: 4
Neonatal single-ventricle palliative surgery: lost in (dead) space? Pediatr Crit Care Med. 2014 Oct; 15(8):777-8. Bhalla A, Markovitz BP. PMID: 25280149.

View in: PubMed Mentions: Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans
The association between the end tidal alveolar dead space fraction and mortality in pediatric acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2012 Jan; 13(1):11-5. Ghuman AK, Newth CJ, Khemani RG. PMID: 21499169.

View in: PubMed Mentions: 19 Fields:
Cri Critical Care Ped Pediatrics
Translation:Humans