Randall C. Wetzel, MD

Title(s)Professor of Pediatrics
SchoolKeck School of Medicine of Usc
AddressCHL Mail Stop 12
Off Campus
Los Angeles CA 90089
Phone+1 323 361 2557
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    Dr. Randall Wetzel is the Chairman of the Department of Anesthesiology Critical Care Medicine at Children’s Hospital Los Angeles, Professor (Tenured) of Anesthesiology and Pediatrics, Keck School of Medicine, University of Southern California, and the Director of The Laura P. and Leland K. Whittier Virtual Pediatric Intensive Care Unit (VPICU) at Children’s Hospital Los Angeles. Prior to coming to CHLA, Dr. Wetzel held various faculty appointments in Anesthesiology and Critical Care Medicine at Johns Hopkins Hospital and University from 1981-1997.

    After completing his undergraduate studies at Durham University in England, he went on to receive his medical degree from the Medical College of St. Bartholomew’s Hospital, London University, England. He moved stateside for his pediatric residency, then fellowship training in Critical Care and Pediatric Cardiology at Rainbow Babies and Children’s Hospital at University Hospitals in Cleveland, Ohio. He was subsequently a fellow in Pediatric Critical Care and Resident/Chief Resident in Anesthesiology/Critical Care Medicine at Johns Hopkins Hospital in Baltimore. Dr. Wetzel returned to England for a fellowship in Pediatric Anesthesia and Critical Care Medicine at the Hospital for Sick Children and Guy’s Hospital in London. In addition, he earned a Master of Science in Business (Medicine) from Johns Hopkins University (1997). He moved to Los Angeles in 1997.

    His current interests in medical informatics led him to develop the VPICU; a Southern California Critical Care Telemedicine Network; he is CEO and Chair of VPS, LLC a Quality Improvement and Data management company with over 120 hospital clients; and he leads a complex big data research team developing data extraction, management, architecture and advanced analytic techniques for highly granular Pediatric Critical Care Data. He has received over $18 million in federal and private foundation grant funding for these projects. He has served as a board member for The American Board of Pediatrics (2000-2003); Editor-in-Chief, the Society for Pediatric Anesthesia (1988-1995). He has authored 94 peer-reviewed articles and 45 book chapters, he is editor of Roger’s Critical Care Medicine and Critical Heart Disease in Infants and Children; and has presented over 100 abstracts at various symposia.

    Dr. Wetzel and his wife Ann have been married 34 years and currently reside in La Cañada, California. They have four wonderful daughters.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Prehospitalization Trauma and Physiologic Factors Associated with the Presence of Post-traumatic Stress 3 Months After PICU Discharge. J Intensive Care Med. 2024 Mar; 39(3):268-276. Chau AN, Eckberg RA, Laksana E, Ehrlich L, Ledbetter DR, Aczon MD, Gold JI, Wetzel RC, Nelson LP. PMID: 38105524.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Ventilator Weaning and Terminal Extubation: Withdrawal of Life-Sustaining Therapy in Children. Secondary Analysis of the Death One Hour After Terminal Extubation Study. Crit Care Med. 2024 03 01; 52(3):396-406. Pringle CP, Filipp SL, Morrison WE, Fainberg NA, Aczon MD, Avesar M, Burkiewicz KF, Chandnani HK, Hsu SC, Laksana E, Ledbetter DR, McCrory MC, Morrow KR, Noguchi AE, O'Brien CE, Ojha A, Ross PA, Shah S, Shah JK, Siegel LB, Tripathi S, Wetzel RC, Zhou AX, Winter MC. PMID: 37889228; PMCID: PMC10922051.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Narrowing the gap: expected versus deployment performance. J Am Med Inform Assoc. 2023 08 18; 30(9):1474-1485. Zhou AX, Aczon MD, Laksana E, Ledbetter DR, Wetzel RC. PMID: 37311708; PMCID: PMC10436142.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. A Novel Application of Spectrograms with Machine Learning Can Detect Patient Ventilator Dyssynchrony. Biomed Signal Process Control. 2023 Sep; 86(Pt C). Obeso I, Yoon B, Ledbetter D, Aczon M, Laksana E, Zhou A, Eckberg RA, Mertan K, Khemani RG, Wetzel R. PMID: 37587924; PMCID: PMC10426752.
      View in: PubMed   Mentions:
    5. Development of a deep learning model that predicts Bi-level positive airway pressure failure. Sci Rep. 2022 05 26; 12(1):8907. Im DD, Laksana E, Ledbetter DR, Aczon MD, Khemani RG, Wetzel RC. PMID: 35618738; PMCID: PMC9135753.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Predicting High Flow Nasal Cannula Failure in an Intensive Care Unit Using a Recurrent Neural Network With Transfer Learning and Input Data Perseveration: Retrospective Analysis. JMIR Med Inform. 2022 Mar 03; 10(3):e31760. Pappy G, Aczon M, Wetzel R, Ledbetter D. PMID: 35238792; PMCID: PMC8931642.
      View in: PubMed   Mentions: 2  
    7. Diagnosis: A Tricky, Never-Ending Business. Pediatr Crit Care Med. 2021 08 01; 22(8):758-761. Wetzel RC. PMID: 34397992.
      View in: PubMed   Mentions:    Fields:    
    8. Continuous Prediction of Mortality in the PICU: A Recurrent Neural Network Model in a Single-Center Dataset. Pediatr Crit Care Med. 2021 06 01; 22(6):519-529. Aczon MD, Ledbetter DR, Laksana E, Ho LV, Wetzel RC. PMID: 33710076; PMCID: PMC8162230.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    9. Machine Learning to Predict Cardiac Death Within 1 Hour After Terminal Extubation. Pediatr Crit Care Med. 2021 02 01; 22(2):161-171. Winter MC, Day TE, Ledbetter DR, Aczon MD, Newth CJL, Wetzel RC, Ross PA. PMID: 33156210.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Interpreting a recurrent neural network's predictions of ICU mortality risk. J Biomed Inform. 2021 02; 114:103672. Ho LV, Aczon M, Ledbetter D, Wetzel R. PMID: 33422663.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    11. The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs. Pediatr Crit Care Med. 2020 09; 21(9):e643-e650. Sachdeva R, Rice TB, Reisner B, Brundage N, Hulbert C, Kaminski A, Wetzel RC. PMID: 32649399; PMCID: PMC7340137.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    12. The impact of extraneous features on the performance of recurrent neural network models in clinical tasks. J Biomed Inform. 2020 02; 102:103351. Laksana E, Aczon M, Ho L, Carlin C, Ledbetter D, Wetzel R. PMID: 31870949.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. The authors reply. Pediatr Crit Care Med. 2019 04; 20(4):399-400. Ledbetter D, Aczon M, Wetzel RC. PMID: 30951002.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Predicting individual physiologically acceptable states at discharge from a pediatric intensive care unit. J Am Med Inform Assoc. 2018 12 01; 25(12):1600-1607. Carlin CS, Ho LV, Ledbetter DR, Aczon MD, Wetzel RC. PMID: 30295770; PMCID: PMC7647156.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Artificial Intelligence: An Inkling of Caution. Pediatr Crit Care Med. 2018 10; 19(10):1004-1005. Wetzel RC, Aczon M, Ledbetter DR. PMID: 30281572.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Applying Machine Learning to Pediatric Critical Care Data. Pediatr Crit Care Med. 2018 07; 19(7):599-608. Williams JB, Ghosh D, Wetzel RC. PMID: 29727354.
      View in: PubMed   Mentions: 13     Fields:    
    17. Low-dose dexmedetomidine as an adjuvant to propofol infusion for children in MRI: A double-cohort study. Paediatr Anaesth. 2018 07; 28(7):639-646. Nagoshi M, Reddy S, Bell M, Cresencia A, Margolis R, Wetzel R, Ross P. PMID: 29882298; PMCID: PMC6105415.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. The Dependence of Machine Learning on Electronic Medical Record Quality. AMIA Annu Symp Proc. 2017; 2017:883-891. Ho LV, Ledbetter D, Aczon M, Wetzel R. PMID: 29854155; PMCID: PMC5977633.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    19. First Get the Data, Then Do the Science! Pediatr Crit Care Med. 2018 04; 19(4):382-383. Wetzel RC. PMID: 29620713.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Development and Validation of an Empiric Tool to Predict Favorable Neurologic Outcomes Among PICU Patients. Crit Care Med. 2018 01; 46(1):108-115. Gupta P, Rettiganti M, Gossett JM, Daufeldt J, Rice TB, Wetzel RC. PMID: 28991830.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Impact of 24/7 In-Hospital Intensivist Coverage on Outcomes in Pediatric Intensive Care. A Multicenter Study. Am J Respir Crit Care Med. 2016 12 15; 194(12):1506-1513. Gupta P, Rettiganti M, Rice TB, Wetzel RC. PMID: 27367580.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    22. Association of Freestanding Children's Hospitals With Outcomes in Children With Critical Illness. Crit Care Med. 2016 Dec; 44(12):2131-2138. Gupta P, Rettiganti M, Fisher PL, Chang AC, Rice TB, Wetzel RC. PMID: 27513535.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    23. Effect of Inhaled Nitric Oxide on Outcomes in Children With Acute Lung Injury: Propensity Matched Analysis From a Linked Database. Crit Care Med. 2016 Oct; 44(10):1901-9. Gupta P, Richardson T, Hall M, Bertoch D, Hebbar KB, Fortenberry JD, Wetzel RC. PMID: 27163193.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    24. Mainstream capnography system for nonintubated children in the postanesthesia care unit: Performance with changing flow rates, and a comparison to side stream capnography. Paediatr Anaesth. 2016 Dec; 26(12):1179-1187. Nagoshi M, Morzov R, Hotz J, Belson P, Matar M, Ross P, Wetzel R. PMID: 27663694.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Pediatric Triage in a Severe Pandemic: Maximizing Survival by Establishing Triage Thresholds. Crit Care Med. 2016 Sep; 44(9):1762-8. Gall C, Wetzel R, Kolker A, Kanter RK, Toltzis P. PMID: 27071069.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansPHPublic Health
    26. Risk factors and outcomes of in-hospital cardiac arrest following pediatric heart operations of varying complexity. Resuscitation. 2016 08; 105:1-7. Gupta P, Rettiganti M, Jeffries HE, Scanlon MC, Ghanayem NS, Daufeldt J, Rice TB, Wetzel RC. PMID: 27185218.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    27. Obesity and Mortality Risk in Critically Ill Children. Pediatrics. 2016 Mar; 137(3):e20152035. Ross PA, Newth CJ, Leung D, Wetzel RC, Khemani RG. PMID: 26908670.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    28. Pediatric Intensive Care Databases for Quality Improvement. J Pediatr Intensive Care. 2016 Sep; 5(3):81-88. Wetzel RC. PMID: 31110890; PMCID: PMC6512415.
      View in: PubMed   Mentions: 13  
    29. Association of house staff training with mortality in children with critical illness. Acta Paediatr. 2016 Feb; 105(2):e60-6. Gupta P, Tang X, Rettiganti M, Lauer C, Kacmarek RM, Rice TB, Markovitz BP, Wetzel RC. PMID: 26399703.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    30. Causal Phenotype Discovery via Deep Networks. AMIA Annu Symp Proc. 2015; 2015:677-86. Kale DC, Che Z, Bahadori MT, Li W, Liu Y, Wetzel R. PMID: 26958203; PMCID: PMC4765623.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    31. Pediatric Index of Cardiac Surgical Intensive Care Mortality Risk Score for Pediatric Cardiac Critical Care. Pediatr Crit Care Med. 2015 Nov; 16(9):846-52. Jeffries HE, Soto-Campos G, Katch A, Gall C, Rice TB, Wetzel R. PMID: 26196254.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    32. Risk factors for mechanical ventilation and reintubation after pediatric heart surgery. J Thorac Cardiovasc Surg. 2016 Feb; 151(2):451-8.e3. Gupta P, Rettiganti M, Gossett JM, Yeh JC, Jeffries HE, Rice TB, Wetzel RC. PMID: 26507405.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    33. Evidence-Based Pediatric Outcome Predictors to Guide the Allocation of Critical Care Resources in a Mass Casualty Event. Pediatr Crit Care Med. 2015 Sep; 16(7):e207-16. Toltzis P, Soto-Campos G, Shelton C, Kuhn EM, Hahn R, Kanter RK, Wetzel RC. PMID: 26121100.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Critical care for rare diseases (and procedures): redux. Pediatr Crit Care Med. 2015 Mar; 16(3):297-9. Fackler J, Lehmann HP, Wetzel RC. PMID: 25738931.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Variation of ventilation practices with center volume after pediatric heart surgery. Clin Cardiol. 2015 Mar; 38(3):178-84. Gupta P, Tang X, Gossett JM, Gall CM, Lauer C, Rice TB, Wetzel RC. PMID: 25707486; PMCID: PMC6710997.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    36. It is too early to declare early or late rescue high-frequency oscillatory ventilation dead--reply. JAMA Pediatr. 2014 Sep; 168(9):863. Gupta P, Kacmarek RM, Wetzel RC. PMID: 25179022.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    37. Epidemiology and outcomes of in-hospital cardiac arrest in critically ill children across hospitals of varied center volume: a multi-center analysis. Resuscitation. 2014 Nov; 85(11):1473-9. Gupta P, Tang X, Gall CM, Lauer C, Rice TB, Wetzel RC. PMID: 25110249.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    38. Algorithms to estimate PaCO2 and pH using noninvasive parameters for children with hypoxemic respiratory failure. Respir Care. 2014 Aug; 59(8):1248-57. Khemani RG, Celikkaya EB, Shelton CR, Kale D, Ross PA, Wetzel RC, Newth CJ. PMID: 24368862.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Association of center volume with outcomes in critically ill children with acute asthma. Ann Allergy Asthma Immunol. 2014 Jul; 113(1):42-7. Gupta P, Tang X, Gossett JM, Gall CM, Lauer C, Rice TB, Carroll CL, Kacmarek RM, Wetzel RC. PMID: 24835583.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. JAMA Pediatr. 2014 Mar; 168(3):243-9. Gupta P, Green JW, Tang X, Gall CM, Gossett JM, Rice TB, Kacmarek RM, Wetzel RC. PMID: 24445980.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    41. The parsimonious pediatric index of mortality*. Pediatr Crit Care Med. 2013 Sep; 14(7):718-9. Marcin JP, Wetzel RC. PMID: 24162957.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    42. Using robotic telecommunications to triage pediatric disaster victims. J Pediatr Surg. 2012 Jan; 47(1):221-4. Burke RV, Berg BM, Vee P, Morton I, Nager A, Neches R, Wetzel R, Upperman JS. PMID: 22244422.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    43. Are all ICUs the same? Paediatr Anaesth. 2011 Jul; 21(7):787-93. Wetzel RC, Sachedeva R, Rice TB. PMID: 21554489.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    44. Who is doing what to whom: a large prospective study of propofol anesthesia in children. Anesth Analg. 2009 Mar; 108(3):695-8. Wetzel RC. PMID: 19224769.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Support for PICUs and the PRISM scoring algorithms. Pediatr Crit Care Med. 2009 Jan; 10(1):143-4. Gorman M, Sachdeva R, Rice T, Wetzel R. PMID: 19131881.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Databases for assessing the outcomes of the treatment of patients with congenital and paediatric cardiac disease--the perspective of critical care. Cardiol Young. 2008 Dec; 18 Suppl 2:130-6. LaRovere JM, Jeffries HE, Sachdeva RC, Rice TB, Wetzel RC, Cooper DS, Bird GL, Ghanayem NS, Checchia PA, Chang AC, Wessel DL. PMID: 19063783.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    47. Calcium: a double-edged sword. Pediatr Crit Care Med. 2007 May; 8(3):300-1. Wetzel RC. PMID: 17496519.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    48. Positive end-expiratory pressure and pressure support in peripheral airways obstruction : work of breathing in intubated children. Intensive Care Med. 2007 Jan; 33(1):120-7. Graham AS, Chandrashekharaiah G, Citak A, Wetzel RC, Newth CJ. PMID: 17111110.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    49. Don't confuse the anesthetic with the anesthesiologist! Anesth Analg. 2006 Oct; 103(4):859-62. Wetzel RC. PMID: 17000794.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    50. Pediatric cardiac critical care patients should be cared for by intensivists. J Am Coll Cardiol. 2006 Jul 04; 48(1):221-2; author reply 222-3. Baden HP, Berger J, Brilli RI, Burns JP, Checchia PA, Dalton HJ, Nadkarni V, Pollack M, Wetzel RC, Zimmerman JJ. PMID: 16814678.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Precise use of medical terminology. Crit Care Med. 2006 Jun; 34(6):1854; author reply 1854-5. Wetzel RC. PMID: 16715005.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Intensivist-led team approach to critical care of children with heart disease. Pediatrics. 2006 May; 117(5):1854-6; author reply 1856-7. Baden HP, Zimmerman JJ, Brilli RJ, Wong H, Wetzel RC, Burns JP, Nadkarni V, Checchia PA, Dalton HJ, Berger J, Pollack M, Notterman D, Green TP, Blumer J, Dean M. PMID: 16651353.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    53. Gastrointestinal morbidity after Norwood palliation for hypoplastic left heart syndrome. Ann Thorac Surg. 2006 Mar; 81(3):982-7. Jeffries HE, Wells WJ, Starnes VA, Wetzel RC, Moromisato DY. PMID: 16488706.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    54. [Assessment of health-related quality of life with the German SF-8. A comparison of telephone and postal survey modes]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2005 Dec; 48(12):1322-9. Erhart M, Wetzel R, Krügel A, Ravens-Sieberer U. PMID: 16261299.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    55. Cumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children. Pediatr Crit Care Med. 2005 Nov; 6(6):642-7. Randolph AG, Forbes PW, Gedeit RG, Arnold JH, Wetzel RC, Luckett PM, O'Neil ME, Venkataraman ST, Meert KL, Cheifetz IM, Cox PN, Hanson JH, Pediatric Acute Lung Injury & Sepsis Investigators (PALISI) Network. PMID: 16276328.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    56. Pressure-rate products and phase angles in children on minimal support ventilation and after extubation. Intensive Care Med. 2005 Dec; 31(12):1700-5. Willis BC, Graham AS, Yoon E, Wetzel RC, Newth CJ. PMID: 16228176.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    57. Telemedicine: basic technical considerations. J Intensive Care Med. 2004 Sep-Oct; 19(5):297-8. Baker LC, Wetzel RC. PMID: 15481113.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    58. Respiratory inductance plethysmography used to diagnose bilateral diaphragmatic paralysis: a case report. Pediatr Crit Care Med. 2004 Jul; 5(4):399-402. Willis BC, Graham AS, Wetzel R, L Newth CJ. PMID: 15215015.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    59. Telemedicine and intensive care: are we ready and willing? J Intensive Care Med. 2004 Mar-Apr; 19(2):117-8. Wetzel RC. PMID: 15070521.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    60. Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study. Hum Gene Ther. 2003 Jul 20; 14(11):1079-88. Flotte TR, Zeitlin PL, Reynolds TC, Heald AE, Pedersen P, Beck S, Conrad CK, Brass-Ernst L, Humphries M, Sullivan K, Wetzel R, Taylor G, Carter BJ, Guggino WB. PMID: 12885347.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCellsCTClinical Trials
    61. Multiple trauma in children: critical care overview. Crit Care Med. 2002 Nov; 30(11 Suppl):S468-77. Wetzel RC, Burns RC. PMID: 12528789.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    62. Critical care for rare diseases. Pediatr Crit Care Med. 2002 Jan; 3(1):89-90. Fackler JC, Wetzel RC. PMID: 12813239.
      View in: PubMed   Mentions: 2     Fields:    
    63. The virtual pediatric intensive care unit. Practice in the new millennium. Pediatr Clin North Am. 2001 Jun; 48(3):795-814. Wetzel RC. PMID: 11411306.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    64. The safety and efficacy of parent-/nurse-controlled analgesia in patients less than six years of age. Anesth Analg. 2000 Sep; 91(3):573-9. Monitto CL, Greenberg RS, Kost-Byerly S, Wetzel R, Billett C, Lebet RM, Yaster M. PMID: 10960379.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
    65. Osteochondritis dissecans: a multicenter study of the European Pediatric Orthopedic Society. J Pediatr Orthop B. 1999 Oct; 8(4):231-45. Hefti F, Beguiristain J, Krauspe R, Möller-Madsen B, Riccio V, Tschauner C, Wetzel R, Zeller R. PMID: 10513356.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCTClinical Trials
    66. Potential paracrine role of the pericardium in the regulation of cardiac function. Cardiovasc Res. 1998 Nov; 40(2):332-42. Mebazaa A, Wetzel RC, Dodd-o JM, Redmond EM, Shah AM, Maeda K, Maistre G, Lakatta EG, Robotham JL. PMID: 9893727.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    67. Gastro-oesophageal reflux: theory over experience? Paediatr Anaesth. 1998; 8(2):101-4. Wetzel RC. PMID: 9549733.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    68. Pressure-support ventilation in children with severe asthma. Crit Care Med. 1996 Sep; 24(9):1603-5. Wetzel RC. PMID: 8797637.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    69. Fatal intramuscular bleeding misdiagnosed as suspected nonaccidental injury. Pediatrics. 1995 May; 95(5):771-3. Wetzel RC, Slater AJ, Dover GJ. PMID: 7724322.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    70. Comparison between endocardial and great vessel endothelial cells: morphology, growth, and prostaglandin release. Am J Physiol. 1995 Jan; 268(1 Pt 2):H250-9. Mebazaa A, Wetzel R, Cherian M, Abraham M. PMID: 7840269.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    71. Endotoxin induces organ-specific endothelial cell injury. Shock. 1995 Jan; 3(1):46-50. Maeda K, Abello PA, Abraham MR, Wetzel RC, Robotham JL, Buchman TG. PMID: 7850579.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    72. 17 beta-Estradiol inhibits flow- and acute hypoxia-induced prostacyclin release from perfused endocardial endothelial cells. Circulation. 1994 Nov; 90(5):2519-24. Redmond EM, Cherian MN, Wetzel RC. PMID: 7955210.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    73. Optimal release time during airway pressure release ventilation in neonatal sheep. Crit Care Med. 1994 Mar; 22(3):486-93. Martin LD, Wetzel RC. PMID: 8125000.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    74. Preoperative evaluation of children. Pediatr Clin North Am. 1994 Feb; 41(1):93-110. Maxwell LG, Deshpande JK, Wetzel RC. PMID: 8295809.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    75. Postoperative analgesia following thoracotomy in children: interpleural catheters. J Pediatr Surg. 1993 Nov; 28(11):1466-70. Tobias JD, Martin LD, Oakes L, Rao B, Wetzel RC. PMID: 8301460.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    76. The intensivist's system. Crit Care Med. 1993 Sep; 21(9 Suppl):S341-4. Wetzel RC. PMID: 8365217.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    77. Cardiorespiratory responses to epidural analgesia in the awake child: a retrospective review of postoperative patients. J Post Anesth Nurs. 1993 Aug; 8(4):257-61. Tobias JD, Wetzel RC, Nichols DG. PMID: 8377135.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    78. Intravascular volume loading reversibly decreases airway cross-sectional area. Chest. 1993 Mar; 103(3):865-70. Wetzel RC, Herold CJ, Zerhouni EA, Robotham JL. PMID: 8449083.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    79. Right and left ventricular cultured endocardial endothelium produces prostacyclin and PGE2. J Mol Cell Cardiol. 1993 Mar; 25(3):245-8. Mebazaa A, Martin LD, Robotham JL, Maeda K, Gabrielson EW, Wetzel RC. PMID: 8510168.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    80. High-resolution computed tomography--physiologic correlation. J Thorac Imaging. 1993; 8(4):265-72. Zerhouni EA, Herold CJ, Brown RH, Wetzel RC, Hirshman CA, Robotham JL, Mitzner W. PMID: 8246324.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    81. Halothane enhances pulmonary artery endothelial eicosanoid release. Anesth Analg. 1992 Dec; 75(6):1007-13. Barnes SD, Martin LD, Wetzel RC. PMID: 1443680.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    82. Extracorporeal membrane oxygenation for perioperative support during congenital tracheal stenosis repair. Anesth Analg. 1992 Nov; 75(5):825-9. Walker LK, Wetzel RC, Haller JA. PMID: 1416139.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    83. Anaesthesia for critically ill children during magnetic resonance imaging. Br J Anaesth. 1992 Nov; 69(5):482-6. Tobin JR, Spurrier EA, Wetzel RC. PMID: 1467081.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    84. Hypoxic bronchodilation. J Appl Physiol (1985). 1992 Sep; 73(3):1202-6. Wetzel RC, Herold CJ, Zerhouni EA, Robotham JL. PMID: 1400037.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    85. Acute effects of increased intravascular volume and hypoxia on the pulmonary circulation: assessment with high-resolution CT. Radiology. 1992 Jun; 183(3):655-62. Herold CJ, Wetzel RC, Robotham JL, Herold SM, Zerhouni EA. PMID: 1584914.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    86. Acute hypoxia alters eicosanoid production of perfused pulmonary artery endothelial cells in culture. Prostaglandins. 1992 Apr; 43(4):371-82. Martin LD, Barnes SD, Wetzel RC. PMID: 1609121.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    87. Airway pressure release ventilation in a neonatal lamb model of acute lung injury. Crit Care Med. 1991 Mar; 19(3):373-8. Martin LD, Wetzel RC, Bilenki AL. PMID: 1999099.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    88. Phenol as an adjuvant anesthetic for tympanostomy tube insertion. Int J Pediatr Otorhinolaryngol. 1991 Feb; 21(1):51-8. Orobello PW, Park RI, Wetzel RC, Belcher LJ, Naclerio RM. PMID: 2037418.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    89. Midazolam-fentanyl intravenous sedation in children: case report of respiratory arrest. Pediatrics. 1990 Sep; 86(3):463-7. Yaster M, Nichols DG, Deshpande JK, Wetzel RC. PMID: 2388795.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    90. Ketamine by continuous infusion for sedation in the pediatric intensive care unit. Crit Care Med. 1990 Aug; 18(8):819-21. Tobias JD, Martin LD, Wetzel RC. PMID: 2379394.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    91. Intrathecal morphine as an adjunct to anesthesia for head and neck surgery. South Med J. 1990 Jun; 83(6):649-52. Tobias JD, Deshpande JK, Wetzel RC, Solca M. PMID: 2356498.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    92. Postoperative analgesia. Use of intrathecal morphine in children. Clin Pediatr (Phila). 1990 Jan; 29(1):44-8. Tobias JD, Deshpande JK, Wetzel RC, Facker J, Maxwell LG, Solca M. PMID: 2403501.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    93. Inspiratory work and response times of a modified pediatric volume ventilator during synchronized intermittent mandatory ventilation and pressure support ventilation. Anesthesiology. 1989 Dec; 71(6):977-81. Martin LD, Rafferty JF, Wetzel RC, Gioia FR. PMID: 2589684.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    94. Prediction of successful primary closure of congenital abdominal wall defects using intraoperative measurements. J Pediatr Surg. 1989 Dec; 24(12):1217-20. Yaster M, Scherer TL, Stone MM, Maxwell LG, Schleien CL, Wetzel RC, Buck JR, Nichols DG, Colombani PM, Dudgeon DL, et al. PMID: 2531789.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    95. Separation of craniopagus Siamese twins using cardiopulmonary bypass and hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 1989 Nov; 98(5 Pt 2):961-7. Cameron DE, Reitz BA, Carson BS, Long DM, Dufresne CR, Vander Kolk CA, Maxwell LG, Tilghman DM, Nichols DG, Wetzel RC, et al. PMID: 2682024.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    96. Pentobarbital attenuates pulmonary vasoconstriction in isolated sheep lungs. Am J Physiol. 1989 Sep; 257(3 Pt 2):H898-903. Wetzel RC, Martin LD. PMID: 2782447.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    97. Age-dependent effects of indomethacin on hypoxic vasoconstriction in neonatal lamb lungs. Pediatr Res. 1988 Jun; 23(6):580-4. Gordon JB, Tod ML, Wetzel RC, McGeady ML, Adkinson NF, Sylvester JT. PMID: 3393389.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    98. Chloramphenicol toxicity in critically ill children with cardiac disease. Crit Care Med. 1987 Nov; 15(11):1069-71. Spear RM, Wetzel RC. PMID: 3677753.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    99. High frequency ventilation. Pediatr Clin North Am. 1987 Feb; 34(1):15-38. Wetzel RC, Gioia FR. PMID: 3543822.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    100. Anesthetic implications of protein C deficiency. Anesth Analg. 1986 Sep; 65(9):982-4. Wetzel RC, Marsh BR, Yaster M, Casella JF. PMID: 3755574.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    101. Arterial blood gas derived variables as estimates of intrapulmonary shunt in critically ill children. Crit Care Med. 1985 Dec; 13(12):1029-33. Dean JM, Wetzel RC, Rogers MC. PMID: 3905259.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    102. Hemodynamic responses in brain dead organ donor patients. Anesth Analg. 1985 Feb; 64(2):125-8. Wetzel RC, Setzer N, Stiff JL, Rogers MC. PMID: 3882020.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    103. Gypsies and acute medical intervention. Pediatrics. 1983 Nov; 72(5):731-5. Wetzel RC, Dean JM, Rogers MC. PMID: 6634280.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
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