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Philippe Friedlich, MD

Title(s)Professor of Clinical Pediatrics and Surgery
AddressCHL Mail Stop 31
Off Campus
Los Angeles CA 90089
Phone+1 323 361 5932
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    Dr. Philippe Friedlich is a Professor of Clinical Pediatrics and Surgery at the University of Southern California and Interim Director & Division Chief for the Center for Fetal and Neonatal Medicine.

    A fellow of the American Academy of Pediatrics, Dr. Friedlich holds memberships with the Society of Pediatric Research and the American Academy of Pediatrics Section on Perinatal Pediatrics. Dr. Friedlich is a member of the California Children’s Medical Services /California Children’s Services NICU Technical Advisory Committee.

    Dr. Friedlich earned his medical degree from the University of Southern California and completed his pediatric residency and internship at the Children’s Hospital Los Angeles. He completed a fellowship in neonatal and perinatal medicine at the University of Southern California Women’s and Children’s Hospital before joining the faculty of the USC division of Neonatal Medicine in 1998. Dr. Friedlich completed in 2004 a Master of Science in Applied Biostatics and Epidemiology from the University of Southern California and earned a MBA in Medical Management from the University of Massachusetts at Amherst in 2006.

    His areas of research interests include the epidemiology of congenital malformations and neonatal healthcare delivery and outcomes. Dr. Friedlich has published over 150 abstracts, peer review articles, book chapters and support strong research collaborations between surgical, medical and healthcare related disciplines in areas of clinical, translational and basic science.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Impact of Confounding on Cost, Survival, and Length-of-Stay Outcomes for Neonates with Hypoplastic Left Heart Syndrome Undergoing Stage 1 Palliation Surgery. Pediatr Cardiol. 2020 Jun; 41(5):996-1011. Gong CL, Song AY, Horak R, Friedlich PS, Lakshmanan A, Pruetz JD, Yieh L, Ram Kumar S, Williams RG. PMID: 32337623.
      View in: PubMed   Mentions:    Fields:    
    2. Proportion of Retinopathy of Prematurity That Was Treated across Regions in the United States. Am J Perinatol. 2019 Nov 18. Cayabyab RG, Song A, Ramanathan R, Friedlich P, Lakshmanan A. PMID: 31739361.
      View in: PubMed   Mentions:    Fields:    
    3. Association of WIC Participation and Growth and Developmental Outcomes in High-Risk Infants. Clin Pediatr (Phila). 2020 Jan; 59(1):53-61. Lakshmanan A, Song AY, Flores-Fenlon N, Parti U, Vanderbilt DL, Friedlich PS, Williams R, Kipke M. PMID: 31672064.
      View in: PubMed   Mentions:    Fields:    
    4. Delivery timing after laser surgery for twin-twin transfusion syndrome. J Perinatol. 2020 02; 40(2):248-255. Chon AH, Chang MR, Chmait HR, Korst LM, Friedlich PS, Chmait RH. PMID: 31611614.
      View in: PubMed   Mentions:    Fields:    
    5. Viewpoints from families for improving transition from NICU-to-home for infants with medical complexity at a safety net hospital: a qualitative study. BMC Pediatr. 2019 07 05; 19(1):223. Lakshmanan A, Kubicek K, Williams R, Robles M, Vanderbilt DL, Mirzaian CB, Friedlich PS, Kipke M. PMID: 31277630.
      View in: PubMed   Mentions:    Fields:    
    6. Smartphones and Text Messaging are Associated With Higher Parent Quality of Life Scores and Enrollment in Early Intervention After NICU Discharge. Clin Pediatr (Phila). 2019 07; 58(8):903-911. Flores-Fenlon N, Song AY, Yeh A, Gateau K, Vanderbilt DL, Kipke M, Friedlich P, Lakshmanan A. PMID: 31088122.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. The association of Trisomy 13 and 18 and hospital discharge outcomes among neonates in California: A retrospective cohort study. Pediatr Neonatol. 2019 12; 60(6):617-622. Haghnazarian E, Hu J, Song AY, Friedlich PS, Lakshmanan A. PMID: 30935949.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Resource utilization patterns using non-invasive ventilation in neonates with respiratory distress syndrome. J Perinatol. 2018 07; 38(7):850-856. Chavez TA, Lakshmanan A, Figueroa L, Iyer N, Stavroudis TA, Garingo A, Friedlich PS, Ramanathan R. PMID: 29795324.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. The Role of Extracorporeal Membrane Oxygenation Simulation Training at Extracorporeal Life Support Organization Centers in the United States. Simul Healthc. 2017 Aug; 12(4):233-239. Weems MF, Friedlich PS, Nelson LP, Rake AJ, Klee L, Stein JE, Stavroudis TA. PMID: 28609315.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Utilization patterns of extracorporeal membrane oxygenation in neonates in the United States 1997-2012. J Pediatr Surg. 2017 Oct; 52(10):1681-1687. Song AY, Chen HA, Chapman R, Govindarajan A, Upperman JS, Burke RV, Stein J, Friedlich PS, Lakshmanan A. PMID: 28622971.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. The impact of preterm birth <37 weeks on parents and families: a cross-sectional study in the 2 years after discharge from the neonatal intensive care unit. Health Qual Life Outcomes. 2017 Feb 16; 15(1):38. Lakshmanan A, Agni M, Lieu T, Fleegler E, Kipke M, Friedlich PS, McCormick MC, Belfort MB. PMID: 28209168.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    12. The Impact of Venoarterial and Venovenous Extracorporeal Membrane Oxygenation on Cerebral Metabolism in the Newborn Brain. PLoS One. 2016; 11(12):e0168578. Reitman AJ, Chapman R, Stein JE, Paquette L, Panigrahy A, Nelson MD, Friedlich P, Wisnowski JL, Bluml S. PMID: 28033354.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Cost consciousness among physicians in the neonatal intensive care unit. J Perinatol. 2016 11; 36(11):1014-1020. Wei D, Osman C, Dukhovny D, Romley J, Hall M, Chin S, Ho T, Friedlich PS, Lakshmanan A. PMID: 27467561.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. The effects of therapeutic hypothermia on cerebral metabolism in neonates with hypoxic-ischemic encephalopathy: An in vivo 1H-MR spectroscopy study. J Cereb Blood Flow Metab. 2016 06; 36(6):1075-86. Wisnowski JL, Wu TW, Reitman AJ, McLean C, Friedlich P, Vanderbilt D, Ho E, Nelson MD, Panigrahy A, Blüml S. PMID: 26661180.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    15. "Tele-rounding" with a remotely controlled mobile robot in the neonatal intensive care unit. J Telemed Telecare. 2016 Mar; 22(2):132-8. Garingo A, Friedlich P, Chavez T, Tesoriero L, Patil S, Jackson P, Seri I. PMID: 26116855.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Sexual Dimorphism in Newborn Vertebrae and Its Potential Implications. J Pediatr. 2015 Aug; 167(2):416-21. Ponrartana S, Aggabao PC, Dharmavaram NL, Fisher CL, Friedlich P, Devaskar SU, Gilsanz V. PMID: 26028289.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    17. Changes in mean arterial blood pressure during sildenafil use in neonates with meconium aspiration syndrome or sepsis. Am J Ther. 2015 Mar-Apr; 22(2):125-31. Limjoco J, Paquette L, Ramanathan R, Seri I, Friedlich P. PMID: 23344111.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Complication risks associated with lower versus upper extremity peripherally inserted central venous catheters in neonates with gastroschisis. J Pediatr Surg. 2015 Apr; 50(4):556-8. Ma M, Garingo A, Jensen AR, Bliss D, Friedlich P. PMID: 25840062.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    19. Acetazolamide for the management of chronic metabolic alkalosis in neonates and infants. Am J Ther. 2014 Nov-Dec; 21(6):477-81. Tam B, Chhay A, Yen L, Tesoriero L, Ramanathan R, Seri I, Friedlich PS. PMID: 23011176.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Brain temperature in neonates with hypoxic-ischemic encephalopathy during therapeutic hypothermia. J Pediatr. 2014 Dec; 165(6):1129-34. Wu TW, McLean C, Friedlich P, Wisnowski J, Grimm J, Panigrahy A, Bluml S, Seri I. PMID: 25151196.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Maintenance of whole-body therapeutic hypothermia during patient transport and magnetic resonance imaging. Pediatr Radiol. 2014 May; 44(5):613-7. Wu TW, McLean C, Friedlich P, Grimm J, Bluml S, Seri I. PMID: 24442339.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Antithrombin III administration in neonates with congenital diaphragmatic hernia during the first three days of extracorporeal membrane oxygenation. J Pediatr Surg. 2013 Sep; 48(9):1837-42. Perry R, Stein J, Young G, Ramanathan R, Seri I, Klee L, Friedlich P. PMID: 24074654.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    23. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013 Jun; 34(6):801-11. Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P. PMID: 23505205.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    24. Dose-dependent hemodynamic and metabolic effects of vasoactive medications in normotensive, anesthetized neonatal piglets. Pediatr Res. 2011 Nov; 70(5):473-9. Nachar RA, Booth EA, Friedlich P, Borzage M, Soleymani S, Wider MD, Seri I. PMID: 21775923.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    25. The use of mobile robotic telemedicine technology in the neonatal intensive care unit. J Perinatol. 2012 Jan; 32(1):55-63. Garingo A, Friedlich P, Tesoriero L, Patil S, Jackson P, Seri I. PMID: 21617643.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. A meta-analysis of dopamine use in hypotensive preterm infants: blood pressure and cerebral hemodynamics. J Perinatol. 2011 Oct; 31(10):647-55. Sassano-Higgins S, Friedlich P, Seri I. PMID: 21273985.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    27. Sensorineural hearing loss at 9-13 years of age in children with a history of neonatal extracorporeal membrane oxygenation. Arch Dis Child Fetal Neonatal Ed. 2011 Mar; 96(2):F128-32. Murray M, Nield T, Larson-Tuttle C, Seri I, Friedlich P. PMID: 20971719.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Should patients be screened for 12S rRNA mutations before treatment with aminoglycosides? Mitochondrion. 2010 Jun; 10(4):391-2. Boles RG, Friedlich P. PMID: 20302974.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    29. Recovery of multipotent progenitors from the peripheral blood of patients requiring extracorporeal membrane oxygenation support. Am J Respir Crit Care Med. 2010 Feb 01; 181(3):226-37. Bui KC, Senadheera D, Wang X, Hendrickson B, Friedlich P, Lutzko C. PMID: 19875689.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    30. Outcome analysis of neonates with congenital diaphragmatic hernia treated with venovenous vs venoarterial extracorporeal membrane oxygenation. J Pediatr Surg. 2009 Sep; 44(9):1691-701. Guner YS, Khemani RG, Qureshi FG, Wee CP, Austin MT, Dorey F, Rycus PT, Ford HR, Friedlich P, Stein JE. PMID: 19735810.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    31. Hydrocortisone for hypotension and vasopressor dependence in preterm neonates: a meta-analysis. J Perinatol. 2010 Jun; 30(6):373-8. Higgins S, Friedlich P, Seri I. PMID: 19693023.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    32. Effects of low oxygen saturation limits on the ductus arteriosus in extremely low birth weight infants. J Perinatol. 2009 Aug; 29(8):553-7. Noori S, Patel D, Friedlich P, Siassi B, Seri I, Ramanathan R. PMID: 19461594.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    33. Failure of ductus arteriosus closure is associated with increased mortality in preterm infants. Pediatrics. 2009 Jan; 123(1):e138-44. Noori S, McCoy M, Friedlich P, Bright B, Gottipati V, Seri I, Sekar K. PMID: 19117835.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    34. State-based analysis of necrotizing enterocolitis outcomes. J Surg Res. 2009 Nov; 157(1):21-9. Guner YS, Friedlich P, Wee CP, Dorey F, Camerini V, Upperman JS. PMID: 19615694.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    35. Increased carotid artery intima-media thickness following venoarterial extracorporeal membrane oxygenation in the neonatal period. J Perinatol. 2008 Dec; 28(12):811-4. Friedlich P, Gonzalez J, Nield T, Keshava H, Stein J, Seri I, Gilsanz V. PMID: 18615090.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    36. Changes in myocardial function and hemodynamics after ligation of the ductus arteriosus in preterm infants. J Pediatr. 2007 Jun; 150(6):597-602. Noori S, Friedlich P, Seri I, Wong P. PMID: 17517241.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    37. Cardiovascular effects of sildenafil in neonates and infants with congenital diaphragmatic hernia and pulmonary hypertension. Neonatology. 2007; 91(2):92-100. Noori S, Friedlich P, Wong P, Garingo A, Seri I. PMID: 17344658.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    38. Hemodynamic changes after low-dosage hydrocortisone administration in vasopressor-treated preterm and term neonates. Pediatrics. 2006 Oct; 118(4):1456-66. Noori S, Friedlich P, Wong P, Ebrahimi M, Siassi B, Seri I. PMID: 17015536.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    39. Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates. J Perinatol. 2006 Aug; 26(8):486-92. Paquette L, Friedlich P, Ramanathan R, Seri I. PMID: 16791261.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. Hospital rates of maternal and neonatal infection in a low-risk population. Matern Child Health J. 2005 Sep; 9(3):307-16. Korst LM, Fridman M, Friedlich PS, Lu MC, Reyes C, Hobel CJ, Chavez GF, Gregory KD. PMID: 16160757.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. Somatosensory lateralization in the newborn brain. Neuroimage. 2006 Jan 01; 29(1):155-61. Erberich SG, Panigrahy A, Friedlich P, Seri I, Nelson MD, Gilles F. PMID: 16112875.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    42. Predictability model of the need for extracorporeal membrane oxygenation in neonates with meconium aspiration syndrome treated with inhaled nitric oxide. J Pediatr Surg. 2005 Jul; 40(7):1090-3. Friedlich P, Noori S, Stein J, Shin C, Burns C, Ramanathan R, Seri I. PMID: 16034750.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    43. MR imaging of newborns by using an MR-compatible incubator with integrated radiofrequency coils: initial experience. Radiology. 2004 May; 231(2):594-601. Blüml S, Friedlich P, Erberich S, Wood JC, Seri I, Nelson MD. PMID: 15128999.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    44. Risk of need for extracorporeal membrane oxygenation support in neonates with congenital diaphragmatic hernia treated with inhaled nitric oxide. J Perinatol. 2004 Mar; 24(3):143-6. Sebald M, Friedlich P, Burns C, Stein J, Noori S, Ramanathan R, Seri I. PMID: 14961042.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    45. Functional MRI in neonates using neonatal head coil and MR compatible incubator. Neuroimage. 2003 Oct; 20(2):683-92. Erberich SG, Friedlich P, Seri I, Nelson MD, Blüml S. PMID: 14568444.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    46. Use of high-frequency jet ventilation in neonates with hypoxemia refractory to high-frequency oscillatory ventilation. J Matern Fetal Neonatal Med. 2003 Jun; 13(6):398-402. Friedlich P, Subramanian N, Sebald M, Noori S, Seri I. PMID: 12962265.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    47. Relationship between fetal monitoring and resuscitative needs: fetal distress versus routine cesarean deliveries. J Perinatol. 2000 Mar; 20(2):101-4. Posen R, Friedlich P, Chan L, Miller D. PMID: 10785885.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. A randomized trial of nasopharyngeal-synchronized intermittent mandatory ventilation versus nasopharyngeal continuous positive airway pressure in very low birth weight infants after extubation. J Perinatol. 1999 Sep; 19(6 Pt 1):413-8. Friedlich P, Lecart C, Posen R, Ramicone E, Chan L, Ramanathan R. PMID: 10685270.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    49. Renal tolerance with the use of intralipid-amphotericin B in low-birth-weight neonates. Am J Perinatol. 1997 Aug; 14(7):377-83. Friedlich PS, Steinberg I, Fujitani A, deLemos RA. PMID: 9263555.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals