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Philippe Friedlich, MD

Title(s)Professor of Clinical Pediatrics and Surgery
Phone+1 323 361 5932
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    Collapse Overview
    Dr. Philippe Friedlich is a Professor of Clinical Pediatrics and Surgery at the University of Southern California and Interim Director & Division Chief for the Center for Fetal and Neonatal Medicine.

    A fellow of the American Academy of Pediatrics, Dr. Friedlich holds memberships with the Society of Pediatric Research and the American Academy of Pediatrics Section on Perinatal Pediatrics. Dr. Friedlich is a member of the California Children’s Medical Services /California Children’s Services NICU Technical Advisory Committee.

    Dr. Friedlich earned his medical degree from the University of Southern California and completed his pediatric residency and internship at the Children’s Hospital Los Angeles. He completed a fellowship in neonatal and perinatal medicine at the University of Southern California Women’s and Children’s Hospital before joining the faculty of the USC division of Neonatal Medicine in 1998. Dr. Friedlich completed in 2004 a Master of Science in Applied Biostatics and Epidemiology from the University of Southern California and earned a MBA in Medical Management from the University of Massachusetts at Amherst in 2006.

    His areas of research interests include the epidemiology of congenital malformations and neonatal healthcare delivery and outcomes. Dr. Friedlich has published over 150 abstracts, peer review articles, book chapters and support strong research collaborations between surgical, medical and healthcare related disciplines in areas of clinical, translational and basic science.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lakshmanan A, Song AY, Flores-Fenlon N, Parti U, Vanderbilt DL, Friedlich PS, Williams R, Kipke M. Association of WIC Participation and Growth and Developmental Outcomes in High-Risk Infants. Clin Pediatr (Phila). 2019 Oct 31; 9922819884583. PMID: 31672064.
      View in: PubMed
    2. Chon AH, Chang MR, Chmait HR, Korst LM, Friedlich PS, Chmait RH. Delivery timing after laser surgery for twin-twin transfusion syndrome. J Perinatol. 2019 Oct 14. PMID: 31611614.
      View in: PubMed
    3. Lakshmanan A, Kubicek K, Williams R, Robles M, Vanderbilt DL, Mirzaian CB, Friedlich PS, Kipke M. Viewpoints from families for improving transition from NICU-to-home for infants with medical complexity at a safety net hospital: a qualitative study. BMC Pediatr. 2019 Jul 05; 19(1):223. PMID: 31277630.
      View in: PubMed
    4. Flores-Fenlon N, Song AY, Yeh A, Gateau K, Vanderbilt DL, Kipke M, Friedlich P, Lakshmanan A. Smartphones and Text Messaging are Associated With Higher Parent Quality of Life Scores and Enrollment in Early Intervention After NICU Discharge. Clin Pediatr (Phila). 2019 Jul; 58(8):903-911. PMID: 31088122.
      View in: PubMed
    5. Haghnazarian E, Hu J, Song AY, Friedlich PS, Lakshmanan A. The association of Trisomy 13 and 18 and hospital discharge outcomes among neonates in California: A retrospective cohort study. Pediatr Neonatol. 2019 Mar 02. PMID: 30935949.
      View in: PubMed
    6. Chavez TA, Lakshmanan A, Figueroa L, Iyer N, Stavroudis TA, Garingo A, Friedlich PS, Ramanathan R. Resource utilization patterns using non-invasive ventilation in neonates with respiratory distress syndrome. J Perinatol. 2018 07; 38(7):850-856. PMID: 29795324.
      View in: PubMed
    7. Weems MF, Friedlich PS, Nelson LP, Rake AJ, Klee L, Stein JE, Stavroudis TA. The Role of Extracorporeal Membrane Oxygenation Simulation Training at Extracorporeal Life Support Organization Centers in the United States. Simul Healthc. 2017 Aug; 12(4):233-239. PMID: 28609315.
      View in: PubMed
    8. Song AY, Chen HA, Chapman R, Govindarajan A, Upperman JS, Burke RV, Stein J, Friedlich PS, Lakshmanan A. Utilization patterns of extracorporeal membrane oxygenation in neonates in the United States 1997-2012. J Pediatr Surg. 2017 Oct; 52(10):1681-1687. PMID: 28622971.
      View in: PubMed
    9. Lakshmanan A, Agni M, Lieu T, Fleegler E, Kipke M, Friedlich PS, McCormick MC, Belfort MB. The impact of preterm birth <37 weeks on parents and families: a cross-sectional study in the 2 years after discharge from the neonatal intensive care unit. Health Qual Life Outcomes. 2017 Feb 16; 15(1):38. PMID: 28209168.
      View in: PubMed
    10. Reitman AJ, Chapman R, Stein JE, Paquette L, Panigrahy A, Nelson MD, Friedlich P, Wisnowski JL, Bluml S. The Impact of Venoarterial and Venovenous Extracorporeal Membrane Oxygenation on Cerebral Metabolism in the Newborn Brain. PLoS One. 2016; 11(12):e0168578. PMID: 28033354.
      View in: PubMed
    11. Wei D, Osman C, Dukhovny D, Romley J, Hall M, Chin S, Ho T, Friedlich PS, Lakshmanan A. Cost consciousness among physicians in the neonatal intensive care unit. J Perinatol. 2016 11; 36(11):1014-1020. PMID: 27467561.
      View in: PubMed
    12. Wisnowski JL, Wu TW, Reitman AJ, McLean C, Friedlich P, Vanderbilt D, Ho E, Nelson MD, Panigrahy A, Blüml S. The effects of therapeutic hypothermia on cerebral metabolism in neonates with hypoxic-ischemic encephalopathy: An in vivo 1H-MR spectroscopy study. J Cereb Blood Flow Metab. 2016 06; 36(6):1075-86. PMID: 26661180.
      View in: PubMed
    13. Garingo A, Friedlich P, Chavez T, Tesoriero L, Patil S, Jackson P, Seri I. "Tele-rounding" with a remotely controlled mobile robot in the neonatal intensive care unit. J Telemed Telecare. 2016 Mar; 22(2):132-8. PMID: 26116855.
      View in: PubMed
    14. Ponrartana S, Aggabao PC, Dharmavaram NL, Fisher CL, Friedlich P, Devaskar SU, Gilsanz V. Sexual Dimorphism in Newborn Vertebrae and Its Potential Implications. J Pediatr. 2015 Aug; 167(2):416-21. PMID: 26028289.
      View in: PubMed
    15. Limjoco J, Paquette L, Ramanathan R, Seri I, Friedlich P. Changes in mean arterial blood pressure during sildenafil use in neonates with meconium aspiration syndrome or sepsis. Am J Ther. 2015 Mar-Apr; 22(2):125-31. PMID: 23344111.
      View in: PubMed
    16. Ma M, Garingo A, Jensen AR, Bliss D, Friedlich P. Complication risks associated with lower versus upper extremity peripherally inserted central venous catheters in neonates with gastroschisis. J Pediatr Surg. 2015 Apr; 50(4):556-8. PMID: 25840062.
      View in: PubMed
    17. Tam B, Chhay A, Yen L, Tesoriero L, Ramanathan R, Seri I, Friedlich PS. Acetazolamide for the management of chronic metabolic alkalosis in neonates and infants. Am J Ther. 2014 Nov-Dec; 21(6):477-81. PMID: 23011176.
      View in: PubMed
    18. Wu TW, McLean C, Friedlich P, Wisnowski J, Grimm J, Panigrahy A, Bluml S, Seri I. Brain temperature in neonates with hypoxic-ischemic encephalopathy during therapeutic hypothermia. J Pediatr. 2014 Dec; 165(6):1129-34. PMID: 25151196.
      View in: PubMed
    19. Wu TW, McLean C, Friedlich P, Grimm J, Bluml S, Seri I. Maintenance of whole-body therapeutic hypothermia during patient transport and magnetic resonance imaging. Pediatr Radiol. 2014 May; 44(5):613-7. PMID: 24442339.
      View in: PubMed
    20. Perry R, Stein J, Young G, Ramanathan R, Seri I, Klee L, Friedlich P. Antithrombin III administration in neonates with congenital diaphragmatic hernia during the first three days of extracorporeal membrane oxygenation. J Pediatr Surg. 2013 Sep; 48(9):1837-42. PMID: 24074654.
      View in: PubMed
    21. Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013 Jun; 34(6):801-11. PMID: 23505205.
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    22. Nachar RA, Booth EA, Friedlich P, Borzage M, Soleymani S, Wider MD, Seri I. Dose-dependent hemodynamic and metabolic effects of vasoactive medications in normotensive, anesthetized neonatal piglets. Pediatr Res. 2011 Nov; 70(5):473-9. PMID: 21775923.
      View in: PubMed
    23. Garingo A, Friedlich P, Tesoriero L, Patil S, Jackson P, Seri I. The use of mobile robotic telemedicine technology in the neonatal intensive care unit. J Perinatol. 2012 Jan; 32(1):55-63. PMID: 21617643.
      View in: PubMed
    24. Sassano-Higgins S, Friedlich P, Seri I. A meta-analysis of dopamine use in hypotensive preterm infants: blood pressure and cerebral hemodynamics. J Perinatol. 2011 Oct; 31(10):647-55. PMID: 21273985.
      View in: PubMed
    25. Murray M, Nield T, Larson-Tuttle C, Seri I, Friedlich P. Sensorineural hearing loss at 9-13 years of age in children with a history of neonatal extracorporeal membrane oxygenation. Arch Dis Child Fetal Neonatal Ed. 2011 Mar; 96(2):F128-32. PMID: 20971719.
      View in: PubMed
    26. Boles RG, Friedlich P. Should patients be screened for 12S rRNA mutations before treatment with aminoglycosides? Mitochondrion. 2010 Jun; 10(4):391-2. PMID: 20302974.
      View in: PubMed
    27. Bui KC, Senadheera D, Wang X, Hendrickson B, Friedlich P, Lutzko C. Recovery of multipotent progenitors from the peripheral blood of patients requiring extracorporeal membrane oxygenation support. Am J Respir Crit Care Med. 2010 Feb 01; 181(3):226-37. PMID: 19875689.
      View in: PubMed
    28. Guner YS, Khemani RG, Qureshi FG, Wee CP, Austin MT, Dorey F, Rycus PT, Ford HR, Friedlich P, Stein JE. Outcome analysis of neonates with congenital diaphragmatic hernia treated with venovenous vs venoarterial extracorporeal membrane oxygenation. J Pediatr Surg. 2009 Sep; 44(9):1691-701. PMID: 19735810.
      View in: PubMed
    29. Higgins S, Friedlich P, Seri I. Hydrocortisone for hypotension and vasopressor dependence in preterm neonates: a meta-analysis. J Perinatol. 2010 Jun; 30(6):373-8. PMID: 19693023.
      View in: PubMed
    30. Noori S, Patel D, Friedlich P, Siassi B, Seri I, Ramanathan R. Effects of low oxygen saturation limits on the ductus arteriosus in extremely low birth weight infants. J Perinatol. 2009 Aug; 29(8):553-7. PMID: 19461594.
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    31. Noori S, McCoy M, Friedlich P, Bright B, Gottipati V, Seri I, Sekar K. Failure of ductus arteriosus closure is associated with increased mortality in preterm infants. Pediatrics. 2009 Jan; 123(1):e138-44. PMID: 19117835.
      View in: PubMed
    32. Guner YS, Friedlich P, Wee CP, Dorey F, Camerini V, Upperman JS. State-based analysis of necrotizing enterocolitis outcomes. J Surg Res. 2009 Nov; 157(1):21-9. PMID: 19615694.
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    33. Friedlich P, Gonzalez J, Nield T, Keshava H, Stein J, Seri I, Gilsanz V. Increased carotid artery intima-media thickness following venoarterial extracorporeal membrane oxygenation in the neonatal period. J Perinatol. 2008 Dec; 28(12):811-4. PMID: 18615090.
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    34. Noori S, Friedlich P, Seri I, Wong P. Changes in myocardial function and hemodynamics after ligation of the ductus arteriosus in preterm infants. J Pediatr. 2007 Jun; 150(6):597-602. PMID: 17517241.
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    35. Noori S, Friedlich P, Wong P, Garingo A, Seri I. Cardiovascular effects of sildenafil in neonates and infants with congenital diaphragmatic hernia and pulmonary hypertension. Neonatology. 2007; 91(2):92-100. PMID: 17344658.
      View in: PubMed
    36. Noori S, Friedlich P, Wong P, Ebrahimi M, Siassi B, Seri I. Hemodynamic changes after low-dosage hydrocortisone administration in vasopressor-treated preterm and term neonates. Pediatrics. 2006 Oct; 118(4):1456-66. PMID: 17015536.
      View in: PubMed
    37. Paquette L, Friedlich P, Ramanathan R, Seri I. Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates. J Perinatol. 2006 Aug; 26(8):486-92. PMID: 16791261.
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    38. Korst LM, Fridman M, Friedlich PS, Lu MC, Reyes C, Hobel CJ, Chavez GF, Gregory KD. Hospital rates of maternal and neonatal infection in a low-risk population. Matern Child Health J. 2005 Sep; 9(3):307-16. PMID: 16160757.
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    39. Erberich SG, Panigrahy A, Friedlich P, Seri I, Nelson MD, Gilles F. Somatosensory lateralization in the newborn brain. Neuroimage. 2006 Jan 01; 29(1):155-61. PMID: 16112875.
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    40. Friedlich P, Noori S, Stein J, Shin C, Burns C, Ramanathan R, Seri I. Predictability model of the need for extracorporeal membrane oxygenation in neonates with meconium aspiration syndrome treated with inhaled nitric oxide. J Pediatr Surg. 2005 Jul; 40(7):1090-3. PMID: 16034750.
      View in: PubMed
    41. Blüml S, Friedlich P, Erberich S, Wood JC, Seri I, Nelson MD. MR imaging of newborns by using an MR-compatible incubator with integrated radiofrequency coils: initial experience. Radiology. 2004 May; 231(2):594-601. PMID: 15128999.
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    42. Sebald M, Friedlich P, Burns C, Stein J, Noori S, Ramanathan R, Seri I. Risk of need for extracorporeal membrane oxygenation support in neonates with congenital diaphragmatic hernia treated with inhaled nitric oxide. J Perinatol. 2004 Mar; 24(3):143-6. PMID: 14961042.
      View in: PubMed
    43. Erberich SG, Friedlich P, Seri I, Nelson MD, Blüml S. Functional MRI in neonates using neonatal head coil and MR compatible incubator. Neuroimage. 2003 Oct; 20(2):683-92. PMID: 14568444.
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    44. Friedlich P, Subramanian N, Sebald M, Noori S, Seri I. Use of high-frequency jet ventilation in neonates with hypoxemia refractory to high-frequency oscillatory ventilation. J Matern Fetal Neonatal Med. 2003 Jun; 13(6):398-402. PMID: 12962265.
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    45. Posen R, Friedlich P, Chan L, Miller D. Relationship between fetal monitoring and resuscitative needs: fetal distress versus routine cesarean deliveries. J Perinatol. 2000 Mar; 20(2):101-4. PMID: 10785885.
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    46. Friedlich P, Lecart C, Posen R, Ramicone E, Chan L, Ramanathan R. A randomized trial of nasopharyngeal-synchronized intermittent mandatory ventilation versus nasopharyngeal continuous positive airway pressure in very low birth weight infants after extubation. J Perinatol. 1999 Sep; 19(6 Pt 1):413-8. PMID: 10685270.
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    47. Friedlich PS, Steinberg I, Fujitani A, deLemos RA. Renal tolerance with the use of intralipid-amphotericin B in low-birth-weight neonates. Am J Perinatol. 1997 Aug; 14(7):377-83. PMID: 9263555.
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