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Richard M. Leahy, PhD

TitleDean's Professor of Electrical Engineering
InstitutionUniversity of Southern California
DepartmentSignal & Image Processing
AddressEEB 400C
University Park Campus
Los Angeles CA 90089-2564
Phone+1 213 740 4659
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    Dr. Leahy's research interests lie in the application of signal and image processing theory to the formation and analysis of biomedical images. His research group is currently involved in the development and analysis of computational methods for formation of positron emission tomography (PET) images with applications in clinical oncology and gene expression imaging in small animals. For the past 15 years, Dr. Leahy has been involved in the development of inverse method for spatio-temporal imaging of neural activity from measurements of magnetoencephalographic (MEG) and electroencephalographic (EEG) data. The results of this research are distributed to the research community in the form of a freely available software package, BrainStorm. Dr. Leahy has also had a long research interest in the analysis of anatomical imagery, and specifically in the automated segmentation and labelling of neuroanatomical images and in extracting surface representations of the cer! ebral cortex from volumetric data. His work is supported by the National Cancer Institute, the National Institute of Mental Health and the National Center for Research Resources.


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    Collapse Research Activities and Funding
    BrainStorm: Highly Extensible Software for Advanced Electrophysiology and MEG/EEG Imaging
    NIH/NIBIB R01EB026299Jun 15, 2018 - Feb 28, 2022
    Role: Principal Investigator
    A Brain Atlas for Mapping Connectivity in Focal Epilepsy
    NIH/NINDS R01NS089212Mar 1, 2015 - Feb 29, 2020
    Role: Co-Principal Investigator
    BrainSuite: Software for Analysis and Visualization of Multimodal Brain Imaging Data
    NIH/NINDS R01NS074980May 1, 2011 - Mar 31, 2022
    Role: Co-Principal Investigator
    Optimized image reconstruction for time-of-flight PET
    NIH/NIBIB R01EB010197Aug 1, 2010 - May 31, 2014
    Role: Principal Investigator
    Tools for Large-Scale Platform-Independent MEG Data Analysis
    NIH/NIBIB R01EB009048Feb 15, 2009 - Mar 31, 2017
    Role: Co-Principal Investigator
    International Symposium on Biomedical Imaging
    NIH/NIBIB R13EB003414Mar 1, 2004 - Feb 28, 2005
    Role: Principal Investigator
    Spatial-Temporal MEG and EEG Source Estimation
    NIH/NIBIB R01EB002010Dec 1, 1994 - Feb 28, 2011
    Role: Principal Investigator
    Spatio-Temporal MEG and EEG Source Estimation
    NIH/NIMH R01MH053213Dec 1, 1994 - Feb 28, 2006
    Role: Principal Investigator
    Statistical Methods for Quantitative PET
    NIH/NIBIB R01EB000363Feb 5, 1994 - Nov 30, 2006
    Role: Principal Investigator
    STATISTICAL METHODS FOR QUANTITATIVE PET
    NIH/NCI R01CA059794Feb 5, 1994 - Jun 30, 2002
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kim B, Fisher BE, Schweighofer N, Leahy RM, Haldar JP, Choi S, Kay DB, Gordon J, Winstein CJ. A comparison of seven different DTI-derived estimates of corticospinal tract structural characteristics in chronic stroke survivors. J Neurosci Methods. 2018 Apr 21; 304:66-75. PMID: 29684462.
      View in: PubMed
    2. Joshi AA, Chong M, Li J, Choi S, Leahy RM. Are you thinking what I'm thinking? Synchronization of resting fMRI time-series across subjects. Neuroimage. 2018 May 15; 172:740-752. PMID: 29428580.
      View in: PubMed
    3. Grinenko O, Li J, Mosher JC, Wang IZ, Bulacio JC, Gonzalez-Martinez J, Nair D, Najm I, Leahy RM, Chauvel P. A fingerprint of the epileptogenic zone in human epilepsies. Brain. 2018 Jan 01; 141(1):117-131. PMID: 29253102.
      View in: PubMed
    4. Dassios G, Fokas AS, Hashemzadeh P, Leahy RM. EEG for current with two dimensional support. IEEE Trans Biomed Eng. 2017 Dec 20. PMID: 29989944.
      View in: PubMed
    5. Habibi A, Damasio A, Ilari B, Veiga R, Joshi AA, Leahy RM, Haldar JP, Varadarajan D, Bhushan C, Damasio H. Childhood Music Training Induces Change in Micro and Macroscopic Brain Structure: Results from a Longitudinal Study. Cereb Cortex. 2017 Nov 08; 1-12. PMID: 29126181.
      View in: PubMed
    6. Joshi AA, Chong M, Leahy RM. BrainSync: An Orthogonal Transformation for Synchronization of fMRI Data Across Subjects. Med Image Comput Comput Assist Interv. 2017 Sep; 10433:486-494. PMID: 29075682.
      View in: PubMed
    7. Tousseyn S, Krishnan B, Wang ZI, Wongwiangjunt S, Nayak CS, Mosher JC, Wu G, Van Paesschen W, Leahy RM, Gonzalez-Martinez JA, Bulacio J, Najm IM, Alexopoulos AV, Nair DR. Connectivity in ictal single photon emission computed tomography perfusion: a cortico-cortical evoked potential study. Brain. 2017 Jul 01; 140(7):1872-1884. PMID: 28582473.
      View in: PubMed
    8. Awate SP, Leahy RM, Joshi AA. Kernel Methods for Riemannian Analysis of Robust Descriptors of the Cerebral Cortex. Inf Process Med Imaging. 2017 Jun; 10265:28-40. PMID: 29398876.
      View in: PubMed
    9. Choi S, Bush AM, Borzage MT, Joshi AA, Mack WJ, Coates TD, Leahy RM, Wood JC. Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients. Neuroimage Clin. 2017; 15:239-246. PMID: 28540180.
      View in: PubMed
    10. Awate SP, Leahy RM, Joshi AA. Riemannian Statistical Analysis of Cortical Geometry with Robustness to Partial Homology and Misalignment. Med Image Comput Comput Assist Interv. 2016 Oct; 9900:237-246. PMID: 28105471.
      View in: PubMed
    11. Bhushan C, Chong M, Choi S, Joshi AA, Haldar JP, Damasio H, Leahy RM. Temporal Non-Local Means Filtering Reveals Real-Time Whole-Brain Cortical Interactions in Resting fMRI. PLoS One. 2016; 11(7):e0158504. PMID: 27391481; PMCID: PMC4938391.
    12. Joshi AA, Leahy RM, Badawi RD, Chaudhari AJ. Registration-Based Morphometry for Shape Analysis of the Bones of the Human Wrist. IEEE Trans Med Imaging. 2016 Feb; 35(2):416-26. PMID: 26353369; PMCID: PMC4779077 [Available on 02/01/17].
    13. Degnan AJ, Wisnowski JL, Choi S, Ceschin R, Bhushan C, Leahy RM, Corby P, Schmithorst VJ, Panigrahy A. Altered Structural and Functional Connectivity in Late Preterm Preadolescence: An Anatomic Seed-Based Study of Resting State Networks Related to the Posteromedial and Lateral Parietal Cortex. PLoS One. 2015; 10(6):e0130686. PMID: 26098888.
      View in: PubMed
    14. Wei M, Joshi AA, Zhang M, Mei L, Manis FR, He Q, Beattie RL, Xue G, Shattuck DW, Leahy RM, Xue F, Houston SM, Chen C, Dong Q, Lu ZL. How age of acquisition influences brain architecture in bilinguals. J Neurolinguistics. 2015 Nov; 36:35-55. PMID: 27695193.
      View in: PubMed
    15. Chambers MC, Bhushan C, Haldar JP, Leahy RM, Shattuck DW. CORRECTING INHOMOGENEITY-INDUCED DISTORTION IN FMRI USING NON-RIGID REGISTRATION. Proc IEEE Int Symp Biomed Imaging. 2015 Apr; 2015:1364-1367. PMID: 26617955.
      View in: PubMed
    16. Bhushan C, Haldar JP, Choi S, Joshi AA, Shattuck DW, Leahy RM. Co-registration and distortion correction of diffusion and anatomical images based on inverse contrast normalization. Neuroimage. 2015 Jul 15; 115:269-80. PMID: 25827811; PMCID: PMC4461504.
    17. Degnan AJ, Wisnowski JL, Choi S, Ceschin R, Bhushan C, Leahy RM, Corby P, Schmithorst VJ, Panigrahy A. Alterations of resting state networks and structural connectivity in relation to the prefrontal and anterior cingulate cortices in late prematurity. Neuroreport. 2015 Jan 07; 26(1):22-6. PMID: 25426826.
      View in: PubMed
    18. Joshi AA, Salloum R, Bhushan C, Leahy RM. Measuring Asymmetric Interactions in Resting State Brain Networks. Inf Process Med Imaging. 2015; 24:399-410. PMID: 26221690; PMCID: PMC4519983.
    19. Niv S, Ashrafulla S, Tuvblad C, Joshi A, Raine A, Leahy R, Baker LA. Childhood EEG frontal alpha power as a predictor of adolescent antisocial behavior: a twin heritability study. Biol Psychol. 2015 Feb; 105:72-6. PMID: 25456277; PMCID: PMC4685041.
    20. Habibi A, Ilari B, Crimi K, Metke M, Kaplan JT, Joshi AA, Leahy RM, Shattuck DW, Choi SY, Haldar JP, Ficek B, Damasio A, Damasio H. An equal start: absence of group differences in cognitive, social, and neural measures prior to music or sports training in children. Front Hum Neurosci. 2014; 8:690. PMID: 25249961; PMCID: PMC4158792.
    21. Zhu W, Li Q, Bai B, Conti PS, Leahy RM. Patlak image estimation from dual time-point list-mode PET data. IEEE Trans Med Imaging. 2014 Apr; 33(4):913-24. PMID: 24710160; PMCID: PMC4209255.
    22. Chaudhari AJ, Leahy RM, Wise BL, Lane NE, Badawi RD, Joshi AA. Global point signature for shape analysis of carpal bones. Phys Med Biol. 2014 Feb 21; 59(4):961-73. PMID: 24503490; PMCID: PMC3966902.
    23. Bai B, Lin Y, Zhu W, Ren R, Li Q, Dahlbom M, DiFilippo F, Leahy RM. MAP reconstruction for Fourier rebinned TOF-PET data. Phys Med Biol. 2014 Feb 21; 59(4):925-49. PMID: 24504374; PMCID: PMC3980855.
    24. Chang YT, Pantazis D, Leahy RM. To cut or not to cut? Assessing the modular structure of brain networks. Neuroimage. 2014 May 01; 91:99-108. PMID: 24440531; PMCID: PMC3965646.
    25. Dutta J, Leahy RM, Li Q. Non-local means denoising of dynamic PET images. PLoS One. 2013; 8(12):e81390. PMID: 24339921.
      View in: PubMed
    26. Bhushan C, Joshi AA, Leahy RM, Haldar JP. Improved B0 -distortion correction in diffusion MRI using interlaced q-space sampling and constrained reconstruction. Magn Reson Med. 2014 Nov; 72(5):1218-32. PMID: 24464424; PMCID: PMC4017008.
    27. Lin Y, Haldar JP, Li Q, Conti PS, Leahy RM. Sparsity Constrained Mixture Modeling for the Estimation of Kinetic Parameters in Dynamic PET. IEEE Trans Med Imaging. 2014 Jan; 33(1):173-85. PMID: 24216681; PMCID: PMC4013253.
    28. Ashrafulla S, Haldar JP, Joshi AA, Leahy RM. Canonical Granger causality between regions of interest. Neuroimage. 2013 Dec; 83:189-99. PMID: 23811410; PMCID: PMC4026328.
    29. Aydore S, Pantazis D, Leahy RM. A note on the phase locking value and its properties. Neuroimage. 2013 Jul 01; 74:231-44. PMID: 23435210; PMCID: PMC3674231.
    30. Haldar JP, Leahy RM. Linear transforms for Fourier data on the sphere: application to high angular resolution diffusion MRI of the brain. Neuroimage. 2013 May 01; 71:233-47. PMID: 23353603; PMCID: PMC3594568.
    31. Joshi AA, Leahy RM, Badawi RD, Chaudhari AJ. MORPHOMETRY FOR EARLY MONITORING OF TREATMENT RESPONSE IN RHEUMATOID ARTHRITIS. Proc IEEE Int Symp Biomed Imaging. 2013; 121-124. PMID: 24026194.
      View in: PubMed
    32. Bai B, Li Q, Leahy RM. Magnetic resonance-guided positron emission tomography image reconstruction. Semin Nucl Med. 2013 Jan; 43(1):30-44. PMID: 23178087; PMCID: PMC3670801.
    33. Bhushan C, Haldar JP, Joshi AA, Leahy RM. Correcting Susceptibility-Induced Distortion in Diffusion-Weighted MRI using Constrained Nonrigid Registration. Signal Inf Process Assoc Annu Summit Conf APSIPA Asia Pac. 2012 Dec; 2012. PMID: 26767197.
      View in: PubMed
    34. Joshi AA, Hu HH, Leahy RM, Goran MI, Nayak KS. Automatic intra-subject registration-based segmentation of abdominal fat from water-fat MRI. J Magn Reson Imaging. 2013 Feb; 37(2):423-30. PMID: 23011805; PMCID: PMC3531568.
    35. Yang Y, Raine A, Joshi AA, Joshi S, Chang YT, Schug RA, Wheland D, Leahy R, Narr KL. Frontal information flow and connectivity in psychopathy. Br J Psychiatry. 2012 Nov; 201(5):408-9. PMID: 22918965.
      View in: PubMed
    36. Joshi AA, Shattuck DW, Leahy RM. A Method for Automated Cortical Surface Registration and Labeling. Biomed Image Regist Proc. 2012 Jul; 7359:180-189. PMID: 26213720.
      View in: PubMed
    37. Wheland D, Joshi AA, McMahon KL, Hansell NK, Martin NG, Wright MJ, Thompson PM, Shattuck DW, Leahy RM. Robust Identification of Partial-Correlation Based Networks with Applications to Cortical Thickness Data. Proc IEEE Int Symp Biomed Imaging. 2012 May; 2012:1551-1554. PMID: 26753056.
      View in: PubMed
    38. Joshi AA, Shattuck DW, Damasio H, Leahy RM. GEODESIC CURVATURE FLOW ON SURFACES FOR AUTOMATIC SULCAL DELINEATION. Proc IEEE Int Symp Biomed Imaging. 2012 May; 2012:430-433. PMID: 26770662.
      View in: PubMed
    39. Dutta J, Ahn S, Li C, Cherry SR, Leahy RM. Joint L1 and total variation regularization for fluorescence molecular tomography. Phys Med Biol. 2012 Mar 21; 57(6):1459-76. PMID: 22390906; PMCID: PMC3380088.
    40. Chang YT, Leahy RM, Pantazis D. Modularity-based graph partitioning using conditional expected models. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Jan; 85(1 Pt 2):016109. PMID: 22400627; PMCID: PMC3880576.
    41. Somayajula S, Joshi AA, Leahy RM. Non-Rigid Image Registration Using Gaussian Mixture Models. Biomed Image Registration. 2012; 7359:286-295. PMID: 26753181.
      View in: PubMed
    42. Simpson GV, Weber DL, Dale CL, Pantazis D, Bressler SL, Leahy RM, Luks TL. Dynamic activation of frontal, parietal, and sensory regions underlying anticipatory visual spatial attention. J Neurosci. 2011 Sep 28; 31(39):13880-9. PMID: 21957250; PMCID: PMC3672245.
    43. Ahn S, Cho S, Li Q, Lin Y, Leahy RM. Optimal rebinning of time-of-flight PET data. IEEE Trans Med Imaging. 2011 Oct; 30(10):1808-18. PMID: 21536530; PMCID: PMC3353661.
    44. Tadel F, Baillet S, Mosher JC, Pantazis D, Leahy RM. Brainstorm: a user-friendly application for MEG/EEG analysis. Comput Intell Neurosci. 2011; 2011:879716. PMID: 21584256; PMCID: PMC3090754.
    45. Vuckovic MG, Li Q, Fisher B, Nacca A, Leahy RM, Walsh JP, Mukherjee J, Williams C, Jakowec MW, Petzinger GM. Exercise elevates dopamine D2 receptor in a mouse model of Parkinson's disease: in vivo imaging with [¹8F]fallypride. Mov Disord. 2010 Dec 15; 25(16):2777-84. PMID: 20960487; PMCID: PMC3273304.
    46. Joshi AA, Chaudhari AJ, Li C, Dutta J, Cherry SR, Shattuck DW, Toga AW, Leahy RM. DigiWarp: a method for deformable mouse atlas warping to surface topographic data. Phys Med Biol. 2010 Oct 21; 55(20):6197-214. PMID: 20885019; PMCID: PMC3051844.
    47. Somayajula S, Panagiotou C, Rangarajan A, Li Q, Arridge SR, Leahy RM. PET image reconstruction using information theoretic anatomical priors. IEEE Trans Med Imaging. 2011 Mar; 30(3):537-49. PMID: 20851790; PMCID: PMC3331595.
    48. Dutta J, Ahn S, Joshi AA, Leahy RM. Illumination pattern optimization for fluorescence tomography: theory and simulation studies. Phys Med Biol. 2010 May 21; 55(10):2961-82. PMID: 20436232; PMCID: PMC3366281.
    49. Joshi AA, Pantazis D, Li Q, Damasio H, Shattuck DW, Toga AW, Leahy RM. Sulcal set optimization for cortical surface registration. Neuroimage. 2010 Apr 15; 50(3):950-9. PMID: 20056160; PMCID: PMC2832615.
    50. Hui HB, Pantazis D, Bressler SL, Leahy RM. Identifying true cortical interactions in MEG using the nulling beamformer. Neuroimage. 2010 Feb 15; 49(4):3161-74. PMID: 19896541; PMCID: PMC2818446.
    51. Li Z, Li Q, Pantazis D, Yu X, Conti PS, Leahy RM. Controlling familywise error rate for matched subspace detection in dynamic FDG PET. IEEE Trans Med Imaging. 2009 Oct; 28(10):1623-31. PMID: 19783499.
      View in: PubMed
    52. Pantazis D, Joshi A, Jiang J, Shattuck DW, Bernstein LE, Damasio H, Leahy RM. Comparison of landmark-based and automatic methods for cortical surface registration. Neuroimage. 2010 Feb 01; 49(3):2479-93. PMID: 19796696; PMCID: PMC2818237.
    53. Mosher JC, Hämäläinen MS, Pantazis D, Hui HB, Burgess RC, Leahy RM. GENERALIZED SIDELOBE CANCELLER FOR MAGNETOENCEPHALOGRAPHY ARRAYS. Proc IEEE Int Symp Biomed Imaging. 2009 Aug 07; 2009:149-152. PMID: 20234848.
      View in: PubMed
    54. Chaudhari AJ, Ahn S, Levenson R, Badawi RD, Cherry SR, Leahy RM. Excitation spectroscopy in multispectral optical fluorescence tomography: methodology, feasibility and computer simulation studies. Phys Med Biol. 2009 Aug 07; 54(15):4687-704. PMID: 19590118; PMCID: PMC2740369.
    55. Dutta J, Ahn S, Joshi AA, Leahy RM. Optimal Illumination Patterns for Fluorescence Tomography. Proc IEEE Int Symp Biomed Imaging. 2009 Jun 28; 2009:1275-1278. PMID: 20711365.
      View in: PubMed
    56. Ahn S, Wang RT, Park CC, Lin A, Leahy RM, Lange K, Smith DJ. Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids. PLoS Comput Biol. 2009 Jun; 5(6):e1000407. PMID: 19521529; PMCID: PMC2690838.
    57. Chaudhari AJ, Joshi AA, Wu Y, Leahy RM, Cherry SR, Badawi RD. Spatial distortion correction and crystal identification for MRI-compatible position-sensitive avalanche photodiode-based PET scanners. IEEE Trans Nucl Sci. 2009 Jun 01; 56(3):549-556. PMID: 20161023.
      View in: PubMed
    58. Joshi A, Pantazis D, Damasio H, Shattuck D, Li Q, Leahy R. Optimization of Landmark Selection for Cortical Surface Registration. Proc IEEE Comput Soc Conf Comput Vis Pattern Recognit. 2009 Jun 01; 20-25:699-706. PMID: 20717476.
      View in: PubMed
    59. Soto JL, Pantazis D, Jerbi K, Lachaux JP, Garnero L, Leahy RM. Detection of event-related modulations of oscillatory brain activity with multivariate statistical analysis of MEG data. Hum Brain Mapp. 2009 Jun; 30(6):1922-34. PMID: 19378281; PMCID: PMC2871701.
    60. Joshi AA, Shattuck DW, Thompson PM, Leahy RM. A parameterization-based numerical method for isotropic and anisotropic diffusion smoothing on non-flat surfaces. IEEE Trans Image Process. 2009 Jun; 18(6):1358-65. PMID: 19423447; PMCID: PMC2773135.
    61. Panagiotou C, Somayajula S, Gibson AP, Schweiger M, Leahy RM, Arridge SR. Information theoretic regularization in diffuse optical tomography. J Opt Soc Am A Opt Image Sci Vis. 2009 May; 26(5):1277-90. PMID: 19412248.
      View in: PubMed
    62. Li C, Mitchell GS, Dutta J, Ahn S, Leahy RM, Cherry SR. A three-dimensional multispectral fluorescence optical tomography imaging system for small animals based on a conical mirror design. Opt Express. 2009 Apr 27; 17(9):7571-85. PMID: 19399136; PMCID: PMC2852255.
    63. Li Z, Li Q, Yu X, Conti PS, Leahy RM. Lesion detection in dynamic FDG-PET using matched subspace detection. IEEE Trans Med Imaging. 2009 Feb; 28(2):230-40. PMID: 19188110.
      View in: PubMed
    64. Cho S, Ahn S, Li Q, Leahy RM. Exact and approximate Fourier rebinning of PET data from time-of-flight to non time-of-flight. Phys Med Biol. 2009 Feb 07; 54(3):467-84. PMID: 19124956; PMCID: PMC4608752.
    65. Joshi A, Leahy R, Toga AW, Shattuck D. A framework for brain registration via simultaneous surface and volume flow. Inf Process Med Imaging. 2009; 21:576-88. PMID: 19694295; PMCID: PMC4512671.
    66. Shattuck DW, Joshi AA, Pantazis D, Kan E, Dutton RA, Sowell ER, Thompson PM, Toga AW, Leahy RM. Semi-automated method for delineation of landmarks on models of the cerebral cortex. J Neurosci Methods. 2009 Apr 15; 178(2):385-92. PMID: 19162074; PMCID: PMC2773140.
    67. Chaudhari AJ, Joshi AA, Bowen SL, Leahy RM, Cherry SR, Badawi RD. Crystal identification in positron emission tomography using nonrigid registration to a Fourier-based template. Phys Med Biol. 2008 Sep 21; 53(18):5011-27. PMID: 18723924; PMCID: PMC2748910.
    68. Pantazis D, Simpson GV, Weber DL, Dale CL, Nichols TE, Leahy RM. A novel ANCOVA design for analysis of MEG data with application to a visual attention study. Neuroimage. 2009 Jan 01; 44(1):164-74. PMID: 18691661; PMCID: PMC2812479.
    69. Ahn S, Chaudhari AJ, Darvas F, Bouman CA, Leahy RM. Fast iterative image reconstruction methods for fully 3D multispectral bioluminescence tomography. Phys Med Biol. 2008 Jul 21; 53(14):3921-42. PMID: 18591735; PMCID: PMC4246001.
    70. Cho S, Ahn S, Li Q, Leahy RM. Analytical properties of time-of-flight PET data. Phys Med Biol. 2008 Jun 07; 53(11):2809-21. PMID: 18460746; PMCID: PMC4608751.
    71. Park CC, Ahn S, Bloom JS, Lin A, Wang RT, Wu T, Sekar A, Khan AH, Farr CJ, Lusis AJ, Leahy RM, Lange K, Smith DJ. Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids. Nat Genet. 2008 Apr; 40(4):421-9. PMID: 18362883; PMCID: PMC3014048.
    72. Ahn S, Leahy RM. Analysis of Resolution and Noise Properties of Nonquadratically Regularized Image Reconstruction Methods for PET. IEEE Trans Med Imaging. 2008 Mar; 27(3):413-24. PMID: 18334436.
      View in: PubMed
    73. Joshi AA, Shattuck DW, Thompson PM, Leahy RM. Surface-constrained volumetric brain registration using harmonic mappings. IEEE Trans Med Imaging. 2007 Dec; 26(12):1657-69. PMID: 18092736; PMCID: PMC4516139.
    74. Joshi AA, Shattuck DW, Thompson PM, Leahy RM. Registration of cortical surfaces using sulcal landmarks for group analysis of MEG data. Int Congr Ser. 2007 Jun 01; 1300:229-232. PMID: 20824115.
      View in: PubMed
    75. Chin MH, Geng AB, Khan AH, Qian WJ, Petyuk VA, Boline J, Levy S, Toga AW, Smith RD, Leahy RM, Smith DJ. A genome-scale map of expression for a mouse brain section obtained using voxelation. Physiol Genomics. 2007 Aug 20; 30(3):313-21. PMID: 17504947; PMCID: PMC3299369.
    76. Cho S, Li Q, Ahn S, Bai B, Leahy RM. Iterative image reconstruction using inverse Fourier rebinning for fully 3-D PET. IEEE Trans Med Imaging. 2007 May; 26(5):745-56. PMID: 17518067.
      View in: PubMed
    77. Jerbi K, Lachaux JP, N'Diaye K, Pantazis D, Leahy RM, Garnero L, Baillet S. Coherent neural representation of hand speed in humans revealed by MEG imaging. Proc Natl Acad Sci U S A. 2007 May 01; 104(18):7676-81. PMID: 17442753; PMCID: PMC1863498.
    78. Cho S, Li Q, Ahn S, Bai B, Leahy RM. Iterative image reconstruction using inverse fourier rebinning for fully 3-D PET. IEEE Trans Med Imaging. 2007 Mar; 26(3):347-58. PMID: 17354640.
      View in: PubMed
    79. Dogdas B, Stout D, Chatziioannou AF, Leahy RM. Digimouse: a 3D whole body mouse atlas from CT and cryosection data. Phys Med Biol. 2007 Feb 07; 52(3):577-87. PMID: 17228106; PMCID: PMC3006167.
    80. Joshi A, Shattuck D, Thompson P, Leahy R. Brain image registration using cortically constrained harmonic mappings. Inf Process Med Imaging. 2007; 20:359-71. PMID: 17633713; PMCID: PMC4511383.
    81. Li Q, Asma E, Ahn S, Leahy RM. A fast fully 4-D incremental gradient reconstruction algorithm for list mode PET data. IEEE Trans Med Imaging. 2007 Jan; 26(1):58-67. PMID: 17243584.
      View in: PubMed
    82. Li Q, Leahy RM. Statistical modeling and reconstruction of randoms precorrected PET data. IEEE Trans Med Imaging. 2006 Dec; 25(12):1565-72. PMID: 17167992.
      View in: PubMed
    83. Küçükaltun-Yildirim E, Pantazis D, Leahy RM. Task-based comparison of inverse methods in magnetoencephalography. IEEE Trans Biomed Eng. 2006 Sep; 53(9):1783-93. PMID: 16941834.
      View in: PubMed
    84. Qi J, Leahy RM. Iterative reconstruction techniques in emission computed tomography. Phys Med Biol. 2006 Aug 07; 51(15):R541-78. PMID: 16861768.
      View in: PubMed
    85. Zavattini G, Vecchi S, Mitchell G, Weisser U, Leahy RM, Pichler BJ, Smith DJ, Cherry SR. A hyperspectral fluorescence system for 3D in vivo optical imaging. Phys Med Biol. 2006 Apr 21; 51(8):2029-43. PMID: 16585843.
      View in: PubMed
    86. Fennema-Notestine C, Ozyurt IB, Clark CP, Morris S, Bischoff-Grethe A, Bondi MW, Jernigan TL, Fischl B, Segonne F, Shattuck DW, Leahy RM, Rex DE, Toga AW, Zou KH, Brown GG. Quantitative evaluation of automated skull-stripping methods applied to contemporary and legacy images: effects of diagnosis, bias correction, and slice location. Hum Brain Mapp. 2006 Feb; 27(2):99-113. PMID: 15986433; PMCID: PMC2408865.
    87. Darvas F, Ermer JJ, Mosher JC, Leahy RM. Generic head models for atlas-based EEG source analysis. Hum Brain Mapp. 2006 Feb; 27(2):129-43. PMID: 16037984.
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    88. Ruangma A, Bai B, Lewis JS, Sun X, Welch MJ, Leahy R, Laforest R. Three-dimensional maximum a posteriori (MAP) imaging with radiopharmaceuticals labeled with three Cu radionuclides. Nucl Med Biol. 2006 Feb; 33(2):217-26. PMID: 16546676.
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    89. Asma E, Leahy RM. Mean and covariance properties of dynamic PET reconstructions from list-mode data. IEEE Trans Med Imaging. 2006 Jan; 25(1):42-54. PMID: 16398413.
      View in: PubMed
    90. Dogdas B, Shattuck DW, Leahy RM. Segmentation of skull and scalp in 3-D human MRI using mathematical morphology. Hum Brain Mapp. 2005 Dec; 26(4):273-85. PMID: 15966000.
      View in: PubMed
    91. Chaudhari AJ, Darvas F, Bading JR, Moats RA, Conti PS, Smith DJ, Cherry SR, Leahy RM. Hyperspectral and multispectral bioluminescence optical tomography for small animal imaging. Phys Med Biol. 2005 Dec 07; 50(23):5421-41. PMID: 16306643.
      View in: PubMed
    92. Pantazis D, Nichols TE, Baillet S, Leahy RM. A comparison of random field theory and permutation methods for the statistical analysis of MEG data. Neuroimage. 2005 Apr 01; 25(2):383-94. PMID: 15784416.
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    93. Joshi AA, Shattuck DW, Thompson PM, Leahy RM. A framework for registration, statistical characterization and classification of cortically constrained functional imaging data. Inf Process Med Imaging. 2005; 19:186-96. PMID: 17354695; PMCID: PMC4512650.
    94. Li Q, Asma E, Qi J, Bading JR, Leahy RM. Accurate estimation of the Fisher information matrix for the PET image reconstruction problem. IEEE Trans Med Imaging. 2004 Sep; 23(9):1057-64. PMID: 15377114.
      View in: PubMed
    95. Yang Y, Tai YC, Siegel S, Newport DF, Bai B, Li Q, Leahy RM, Cherry SR. Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging. Phys Med Biol. 2004 Jun 21; 49(12):2527-45. PMID: 15272672.
      View in: PubMed
    96. Singh RP, Liu D, Chaudhari A, Cherry SR, Leahy RM, Smith DJ. Investigation of different transcript quantitation tools for high-throughput mapping of brain gene expression using voxelation. J Mol Histol. 2004 May; 35(4):397-402. PMID: 15503813.
      View in: PubMed
    97. Joshi AA, Shattuck DW, Thompson PM, Leahy RM. CORTICAL SURFACE PARAMETERIZATION BY P-HARMONIC ENERGY MINIMIZATION. Proc IEEE Int Symp Biomed Imaging. 2004 Apr 01; 1:428-431. PMID: 20721316.
      View in: PubMed
    98. Pantazis D, Nichols TE, Baillet S, Leahy RM. Spatiotemporal localization of significant activation in MEG using permutation tests. Inf Process Med Imaging. 2003 Jul; 18:512-23. PMID: 15344484.
      View in: PubMed
    99. Singh RP, Brown VM, Chaudhari A, Khan AH, Ossadtchi A, Sforza DM, Meadors AK, Cherry SR, Leahy RM, Smith DJ. High-resolution voxelation mapping of human and rodent brain gene expression. J Neurosci Methods. 2003 May 30; 125(1-2):93-101. PMID: 12763235.
      View in: PubMed
    100. Leil TA, Ossadtchi A, Nichols TE, Leahy RM, Smith DJ. Genes regulated by learning in the hippocampus. J Neurosci Res. 2003 Mar 15; 71(6):763-8. PMID: 12605401.
      View in: PubMed
    101. Khan AH, Ossadtchi A, Leahy RM, Smith DJ. Error-correcting microarray design. Genomics. 2003 Feb; 81(2):157-65. PMID: 12620393.
      View in: PubMed
    102. Ossadtchi A, Brown VM, Khan AH, Cherry SR, Nichols TE, Leahy RM, Smith DJ. Statistical analysis of multiplex brain gene expression images. Neurochem Res. 2002 Oct; 27(10):1113-21. PMID: 12462409.
      View in: PubMed
    103. Berger F, Lee YP, Loening AM, Chatziioannou A, Freedland SJ, Leahy R, Lieberman JR, Belldegrun AS, Sawyers CL, Gambhir SS. Whole-body skeletal imaging in mice utilizing microPET: optimization of reproducibility and applications in animal models of bone disease. Eur J Nucl Med Mol Imaging. 2002 Sep; 29(9):1225-36. PMID: 12418463.
      View in: PubMed
    104. Brown VM, Ossadtchi A, Khan AH, Yee S, Lacan G, Melega WP, Cherry SR, Leahy RM, Smith DJ. Multiplex three-dimensional brain gene expression mapping in a mouse model of Parkinson's disease. Genome Res. 2002 Jun; 12(6):868-84. PMID: 12045141; PMCID: PMC1383741.
    105. Shattuck DW, Leahy RM. BrainSuite: an automated cortical surface identification tool. Med Image Anal. 2002 Jun; 6(2):129-42. PMID: 12045000.
      View in: PubMed
    106. Leil TA, Ossadtchi A, Cortes JS, Leahy RM, Smith DJ. Finding new candidate genes for learning and memory. J Neurosci Res. 2002 Apr 15; 68(2):127-37. PMID: 11948658.
      View in: PubMed
    107. Nichols TE, Qi J, Asma E, Leahy RM. Spatiotemporal reconstruction of list-mode PET data. IEEE Trans Med Imaging. 2002 Apr; 21(4):396-404. PMID: 12022627.
      View in: PubMed
    108. Brown VM, Ossadtchi A, Khan AH, Gambhir SS, Cherry SR, Leahy RM, Smith DJ. Gene expression tomography. Physiol Genomics. 2002 Feb 28; 8(2):159-67. PMID: 11875194.
      View in: PubMed
    109. Brown VM, Ossadtchi A, Khan AH, Cherry SR, Leahy RM, Smith DJ. High-throughput imaging of brain gene expression. Genome Res. 2002 Feb; 12(2):244-54. PMID: 11827944.
      View in: PubMed
    110. Qi J, Leahy RM. A theoretical study of the contrast recovery and variance of MAP reconstructions from PET data. IEEE Trans Med Imaging. 1999 Apr; 18(4):293-305. PMID: 10385287.
      View in: PubMed
    111. Leahy RM, Mosher JC, Spencer ME, Huang MX, Lewine JD. A study of dipole localization accuracy for MEG and EEG using a human skull phantom. Electroencephalogr Clin Neurophysiol. 1998 Aug; 107(2):159-73. PMID: 9751287.
      View in: PubMed