Nicolas Schweighofer, MS, PhD

SchoolHerman Ostrow School of Dentistry of Usc
AddressCHP 155
Health Sciences Campus
Los Angeles CA 90089-9006
Phone+1 323 442 1838
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    Collapse Overview 
    Collapse Overview
    Dr. Nicolas Schweighofer co-founded Computational Neurorehabilitation, an emerging field at the intersection of Neurorehabilitation, Computational Neuroscience, Motor Control and Learning, and Artificial Intelligence (AI). The overarching goals of Computational Neurorehabilitation are to understand and to further improve motor recovery following neurologic injury by mathematically modeling and simulating the neural processes underlying the change in behavior due to rehabilitation. In his current research, he is investigating how predictive models of recovery, informed by the neuroscience of stroke recovery and motor learning, as well as large datasets, can provide the basis for AI methods that suggest timing, dosage, and content of rehabilitation. Such an approach will transform neurorehabilitation by guiding clinicians, patients, and health providers in the optimization of treatments via precision rehabilitation.

    Collapse Research 
    Collapse Research Activities and Funding
    Fast training promotes recovery of arm movements post-stroke via cerebellar-mediated anticipatory feedforward control
    NIH R21NS120274Sep 30, 2020 - Aug 31, 2022
    Role: Principal Investigator
    Optimizing sensori-motor training post-stroke
    NIH R56NS100528Sep 28, 2017 - Jul 31, 2021
    Role: Principal Investigator
    Optimizing the Dose of Rehabilitation After Stroke
    NIH R01HD065438Jan 10, 2011 - Dec 31, 2017
    Role: Principal Investigator
    Task Practice Schedules to Enhance Recovery after Stroke
    NIH R03HD050591Jul 1, 2005 - Jun 30, 2008
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Force Reserve Predicts Compensation in Reaching Movement with Induced Shoulder Strength Deficit. J Neurophysiol. 2024 Jul 10. Faity G, Barradas VR, Schweighofer N, Mottet D. PMID: 38985941.
      View in: PubMed   Mentions:
    2. Aberrant decision-making as a risk factor for falls in aging. Front Aging Neurosci. 2024; 16:1384242. Jain S, Schweighofer N, Finley JM. PMID: 38979111; PMCID: PMC11229407.
      View in: PubMed   Mentions:
    3. NSF DARE-Transforming modeling in neurorehabilitation: Four threads for catalyzing progress. J Neuroeng Rehabil. 2024 04 03; 21(1):46. Valero-Cuevas FJ, Finley J, Orsborn A, Fung N, Hicks JL, Huang HH, Reinkensmeyer D, Schweighofer N, Weber D, Steele KM. PMID: 38570842; PMCID: PMC10988973.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Initial development of skill with a reversed bicycle and a case series of experienced riders. Sci Rep. 2024 02 21; 14(1):4334. Magnard J, Macaulay TR, Schroeder ET, Laine C, Gordon J, Schweighofer N. PMID: 38383561; PMCID: PMC10881966.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Multi-Site Identification and Generalization of Clusters of Walking Behaviors in Individuals With Chronic Stroke and Neurotypical Controls. Neurorehabil Neural Repair. 2023 Dec; 37(11-12):810-822. Sánchez N, Schweighofer N, Mulroy SJ, Roemmich RT, Kesar TM, Torres-Oviedo G, Fisher BE, Finley JM, Winstein CJ. PMID: 37975184; PMCID: PMC10872629.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Theoretical limits on the speed of learning inverse models explain the rate of adaptation in arm reaching tasks. Neural Netw. 2024 Feb; 170:376-389. Barradas VR, Koike Y, Schweighofer N. PMID: 38029719.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Multi-site identification and generalization of clusters of walking behaviors in individuals with chronic stroke and neurotypical controls. bioRxiv. 2023 Oct 30. Sánchez N, Schweighofer N, Mulroy SJ, Roemmich RT, Kesar TM, Torres-Oviedo G, Fisher BE, Finley JM, Winstein CJ. PMID: 37214916; PMCID: PMC10197630.
      View in: PubMed   Mentions:
    8. Reinforcement learning establishes a minimal metacognitive process to monitor and control motor learning performance. Nat Commun. 2023 07 08; 14(1):3988. Sugiyama T, Schweighofer N, Izawa J. PMID: 37422476; PMCID: PMC10329706.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Moderate-intensity cardiovascular exercise performed before motor practice attenuates offline implicit motor learning in stroke survivors but not age-matched neurotypical adults. Exp Brain Res. 2023 Aug; 241(8):2019-2032. Bonuzzi GMG, Bastos FH, Schweighofer N, Wade E, Winstein CJ, Torriani-Pasin C. PMID: 37395857.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Long-term forecasting of a motor outcome following rehabilitation in chronic stroke via a hierarchical bayesian dynamic model. J Neuroeng Rehabil. 2023 06 29; 20(1):83. Schweighofer N, Ye D, Luo H, D'Argenio DZ, Winstein C. PMID: 37386512; PMCID: PMC10311775.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Gait speed and individual characteristics are related to specific gait metrics in neurotypical adults. Sci Rep. 2023 05 18; 13(1):8069. Bonilla Yanez M, Kettlety SA, Finley JM, Schweighofer N, Leech KA. PMID: 37202435; PMCID: PMC10195830.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Association of Brain Age, Lesion Volume, and Functional Outcome in Patients With Stroke. Neurology. 2023 05 16; 100(20):e2103-e2113. Liew SL, Schweighofer N, Cole JH, Zavaliangos-Petropulu A, Lo BP, Han LKM, Hahn T, Schmaal L, Donnelly MR, Jeong JN, Wang Z, Abdullah A, Kim JH, Hutton A, Barisano G, Borich MR, Boyd LA, Brodtmann A, Buetefisch CM, Byblow WD, Cassidy JM, Charalambous CC, Ciullo V, Conforto AB, Dacosta-Aguayo R, DiCarlo JA, Domin M, Dula AN, Egorova-Brumley N, Feng W, Geranmayeh F, Gregory CM, Hanlon CA, Hayward K, Holguin JA, Hordacre B, Jahanshad N, Kautz SA, Khlif MS, Kim H, Kuceyeski A, Lin DJ, Liu J, Lotze M, MacIntosh BJ, Margetis JL, Mataro M, Mohamed FB, Olafson ER, Park G, Piras F, Revill KP, Roberts P, Robertson AD, Sanossian N, Schambra HM, Seo NJ, Soekadar SR, Spalletta G, Stinear CM, Taga M, Tang WK, Thielman GT, Vecchio D, Ward NS, Westlye LT, Winstein CJ, Wittenberg GF, Wolf SL, Wong KA, Yu C, Cramer SC, Thompson PM. PMID: 37015818; PMCID: PMC10186236.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    13. Adaptive control is reversed between hands after left hemisphere stroke and lost following right hemisphere stroke. Proc Natl Acad Sci U S A. 2023 02 07; 120(6):e2212726120. Varghese R, Gordon J, Sainburg RL, Winstein CJ, Schweighofer N. PMID: 36716370; PMCID: PMC9963612.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults. J Neuroeng Rehabil. 2023 01 27; 20(1):14. Kettlety SA, Finley JM, Reisman DS, Schweighofer N, Leech KA. PMID: 36703214; PMCID: PMC9881336.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Increased cognitive load in immersive virtual reality during visuomotor adaptation is associated with decreased long-term retention and context transfer. J Neuroeng Rehabil. 2022 10 05; 19(1):106. Juliano JM, Schweighofer N, Liew SL. PMID: 36199101; PMCID: PMC9532821.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Rey-Osterrieth complex figure recall scores and motor skill learning in older adults: A non-linear mixed effect model-based analysis. Hum Mov Sci. 2022 Dec; 86:103004. Wang P, Lingo VanGilder J, Schweighofer N, Schaefer SY. PMID: 36191575.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Essential Role of Social Context and Self-Efficacy in Daily Paretic Arm/Hand Use After Stroke: An Ecological Momentary Assessment Study With Accelerometry. Arch Phys Med Rehabil. 2023 03; 104(3):390-402. Chen YA, Lewthwaite R, Schweighofer N, Monterosso JR, Fisher BE, Winstein C. PMID: 36167117.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. Corpus Callosal Microstructure Predicts Bimanual Motor Performance in Chronic Stroke Survivors: a Preliminary Cross-Sectional Study. Top Stroke Rehabil. 2023 09; 30(6):626-634. Varghese R, Chang B, Kim B, Liew SL, Schweighofer N, Winstein CJ. PMID: 35856402; PMCID: PMC9852360.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Design of an Isometric End-Point Force Control Task for Electromyography Normalization and Muscle Synergy Extraction From the Upper Limb Without Maximum Voluntary Contraction. Front Hum Neurosci. 2022; 16:805452. Cho W, Barradas VR, Schweighofer N, Koike Y. PMID: 35693543; PMCID: PMC9184761.
      View in: PubMed   Mentions: 2  
    20. Chronic Stroke Sensorimotor Impairment Is Related to Smaller Hippocampal Volumes: An ENIGMA Analysis. J Am Heart Assoc. 2022 05 17; 11(10):e025109. Zavaliangos-Petropulu A, Lo B, Donnelly MR, Schweighofer N, Lohse K, Jahanshad N, Barisano G, Banaj N, Borich MR, Boyd LA, Buetefisch CM, Byblow WD, Cassidy JM, Charalambous CC, Conforto AB, DiCarlo JA, Dula AN, Egorova-Brumley N, Etherton MR, Feng W, Fercho KA, Geranmayeh F, Hanlon CA, Hayward KS, Hordacre B, Kautz SA, Khlif MS, Kim H, Kuceyeski A, Lin DJ, Liu J, Lotze M, MacIntosh BJ, Margetis JL, Mohamed FB, Piras F, Ramos-Murguialday A, Revill KP, Roberts PS, Robertson AD, Schambra HM, Seo NJ, Shiroishi MS, Stinear CM, Soekadar SR, Spalletta G, Taga M, Tang WK, Thielman GT, Vecchio D, Ward NS, Westlye LT, Werden E, Winstein C, Wittenberg GF, Wolf SL, Wong KA, Yu C, Brodtmann A, Cramer SC, Thompson PM, Liew SL. PMID: 35574963; PMCID: PMC9238563.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Virtuous and Vicious Cycles of Arm Use and Function Post-stroke. Front Neurol. 2022; 13:804211. Ballester BR, Winstein C, Schweighofer N. PMID: 35422752; PMCID: PMC9004626.
      View in: PubMed   Mentions: 5  
    22. Corticospinal Tract Lesion Load Originating From Both Ventral Premotor and Primary Motor Cortices Are Associated With Post-stroke Motor Severity. Neurorehabil Neural Repair. 2022 03; 36(3):179-182. Ito KL, Kim B, Liu J, Soekadar SR, Winstein C, Yu C, Cramer SC, Schweighofer N, Liew SL. PMID: 34951947; PMCID: PMC8901562.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    23. Effort, success, and side of lesion determine arm choice in individuals with chronic stroke. J Neurophysiol. 2022 01 01; 127(1):255-266. Kim S, Han CE, Kim B, Winstein CJ, Schweighofer N. PMID: 34879206; PMCID: PMC8782657.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    24. Younger and Late Middle-Aged Adults Exhibit Different Patterns of Cognitive-Motor Interference During Locomotor Adaptation, With No Disruption of Savings. Front Aging Neurosci. 2021; 13:729284. Rossi C, Roemmich RT, Schweighofer N, Bastian AJ, Leech KA. PMID: 34899267; PMCID: PMC8664558.
      View in: PubMed   Mentions: 3  
    25. Smaller spared subcortical nuclei are associated with worse post-stroke sensorimotor outcomes in 28 cohorts worldwide. Brain Commun. 2021; 3(4):fcab254. Liew SL, Zavaliangos-Petropulu A, Schweighofer N, Jahanshad N, Lang CE, Lohse KR, Banaj N, Barisano G, Baugh LA, Bhattacharya AK, Bigjahan B, Borich MR, Boyd LA, Brodtmann A, Buetefisch CM, Byblow WD, Cassidy JM, Charalambous CC, Ciullo V, Conforto AB, Craddock RC, Dula AN, Egorova N, Feng W, Fercho KA, Gregory CM, Hanlon CA, Hayward KS, Holguin JA, Hordacre B, Hwang DH, Kautz SA, Khlif MS, Kim B, Kim H, Kuceyeski A, Lo B, Liu J, Lin D, Lotze M, MacIntosh BJ, Margetis JL, Mohamed FB, Nordvik JE, Petoe MA, Piras F, Raju S, Ramos-Murguialday A, Revill KP, Roberts P, Robertson AD, Schambra HM, Seo NJ, Shiroishi MS, Soekadar SR, Spalletta G, Stinear CM, Suri A, Tang WK, Thielman GT, Thijs VN, Vecchio D, Ward NS, Westlye LT, Winstein CJ, Wittenberg GF, Wong KA, Yu C, Wolf SL, Cramer SC, Thompson PM, ENIGMA Stroke Recovery Working Group . PMID: 34805997; PMCID: PMC8598999.
      View in: PubMed   Mentions: 7  
    26. Corticospinal Tract Microstructure Predicts Distal Arm Motor Improvements in Chronic Stroke. J Neurol Phys Ther. 2021 10 01; 45(4):273-281. Kim B, Schweighofer N, Haldar JP, Leahy RM, Winstein CJ. PMID: 34269747; PMCID: PMC8460613.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    27. Validating Habitual and Goal-Directed Decision-Making Performance Online in Healthy Older Adults. Front Aging Neurosci. 2021; 13:702810. Ito KL, Cao L, Reinberg R, Keller B, Monterosso J, Schweighofer N, Liew SL. PMID: 34267650; PMCID: PMC8276057.
      View in: PubMed   Mentions:
    28. Different Biomechanical Variables Explain Within-Subjects Versus Between-Subjects Variance in Step Length Asymmetry Post-Stroke. IEEE Trans Neural Syst Rehabil Eng. 2021; 29:1188-1198. Sanchez N, Schweighofer N, Finley JM. PMID: 34138713; PMCID: PMC8290879.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. Stochastic optimal feedforward-feedback control determines timing and variability of arm movements with or without vision. PLoS Comput Biol. 2021 06; 17(6):e1009047. Berret B, Conessa A, Schweighofer N, Burdet E. PMID: 34115757; PMCID: PMC8221793.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    30. Dissociating Sensorimotor Recovery and Compensation During Exoskeleton Training Following Stroke. Front Hum Neurosci. 2021; 15:645021. Nibras N, Liu C, Mottet D, Wang C, Reinkensmeyer D, Remy-Neris O, Laffont I, Schweighofer N. PMID: 33994981; PMCID: PMC8120113.
      View in: PubMed   Mentions: 5  
    31. A Novel Combination of Accelerometry and Ecological Momentary Assessment for Post-Stroke Paretic Arm/Hand Use: Feasibility and Validity. J Clin Med. 2021 Mar 23; 10(6). Chen YA, Demers M, Lewthwaite R, Schweighofer N, Monterosso JR, Fisher BE, Winstein C. PMID: 33807014; PMCID: PMC8005066.
      View in: PubMed   Mentions: 3  
    32. Computational reproductions of external force field adaption without assuming desired trajectories. Neural Netw. 2021 Jul; 139:179-198. Kambara H, Takagi A, Shimizu H, Kawase T, Yoshimura N, Schweighofer N, Koike Y. PMID: 33740581.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    33. The probability of choosing both hands depends on an interaction between motor capacity and limb-specific control in chronic stroke. Exp Brain Res. 2020 Nov; 238(11):2569-2579. Varghese R, Kutch JJ, Schweighofer N, Winstein CJ. PMID: 32880681; PMCID: PMC7554092.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    34. The Efficiency, Efficacy, and Retention of Task Practice in Chronic Stroke. Neurorehabil Neural Repair. 2020 10; 34(10):881-890. Wang C, Winstein C, D'Argenio DZ, Schweighofer N. PMID: 32830617; PMCID: PMC7572736.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    35. Electrical coupling controls dimensionality and chaotic firing of inferior olive neurons. PLoS Comput Biol. 2020 07; 16(7):e1008075. Hoang H, Lang EJ, Hirata Y, Tokuda IT, Aihara K, Toyama K, Kawato M, Schweighofer N. PMID: 32730255; PMCID: PMC7419012.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    36. The ENIGMA Stroke Recovery Working Group: Big data neuroimaging to study brain-behavior relationships after stroke. Hum Brain Mapp. 2022 01; 43(1):129-148. Liew SL, Zavaliangos-Petropulu A, Jahanshad N, Lang CE, Hayward KS, Lohse KR, Juliano JM, Assogna F, Baugh LA, Bhattacharya AK, Bigjahan B, Borich MR, Boyd LA, Brodtmann A, Buetefisch CM, Byblow WD, Cassidy JM, Conforto AB, Craddock RC, Dimyan MA, Dula AN, Ermer E, Etherton MR, Fercho KA, Gregory CM, Hadidchi S, Holguin JA, Hwang DH, Jung S, Kautz SA, Khlif MS, Khoshab N, Kim B, Kim H, Kuceyeski A, Lotze M, MacIntosh BJ, Margetis JL, Mohamed FB, Piras F, Ramos-Murguialday A, Richard G, Roberts P, Robertson AD, Rondina JM, Rost NS, Sanossian N, Schweighofer N, Seo NJ, Shiroishi MS, Soekadar SR, Spalletta G, Stinear CM, Suri A, Tang WKW, Thielman GT, Vecchio D, Villringer A, Ward NS, Werden E, Westlye LT, Winstein C, Wittenberg GF, Wong KA, Yu C, Cramer SC, Thompson PM. PMID: 32310331; PMCID: PMC8675421.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    37. When 90% of the variance is not enough: residual EMG from muscle synergy extraction influences task performance. J Neurophysiol. 2020 06 01; 123(6):2180-2190. Barradas VR, Kutch JJ, Kawase T, Koike Y, Schweighofer N. PMID: 32267198; PMCID: PMC7311728.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    38. Differences in high-definition transcranial direct current stimulation over the motor hotspot versus the premotor cortex on motor network excitability. Sci Rep. 2019 11 26; 9(1):17605. Lefebvre S, Jann K, Schmiesing A, Ito K, Jog M, Schweighofer N, Wang DJJ, Liew SL. PMID: 31772347; PMCID: PMC6879500.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    39. Minimizing Precision-Weighted Sensory Prediction Errors via Memory Formation and Switching in Motor Adaptation. J Neurosci. 2019 11 13; 39(46):9237-9250. Oh Y, Schweighofer N. PMID: 31582527; PMCID: PMC6855676.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    40. Locomotor skill acquisition in virtual reality shows sustained transfer to the real world. J Neuroeng Rehabil. 2019 09 14; 16(1):113. Kim A, Schweighofer N, Finley JM. PMID: 31521167; PMCID: PMC6744642.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    41. Dosage Matters. Stroke. 2019 07; 50(7):1831-1837. Winstein C, Kim B, Kim S, Martinez C, Schweighofer N. PMID: 31164067.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCTClinical Trials
    42. Correction to: Dissociating motor learning from recovery in exoskeleton training post-stroke. J Neuroeng Rehabil. 2018 Dec 17; 15(1):120. Schweighofer N, Wang C, Mottet D, Laffont I, Bakhti K, Reinkensmeyer DJ, Rémy-Néris O. PMID: 30558647; PMCID: PMC6297949.
      View in: PubMed   Mentions:    Fields:    
    43. Sensory prediction errors, not performance errors, update memories in visuomotor adaptation. Sci Rep. 2018 11 07; 8(1):16483. Lee K, Oh Y, Izawa J, Schweighofer N. PMID: 30405177; PMCID: PMC6220348.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    44. Measuring Habitual Arm Use Post-stroke With a Bilateral Time-Constrained Reaching Task. Front Neurol. 2018; 9:883. Kim S, Park H, Han CE, Winstein CJ, Schweighofer N. PMID: 30416480; PMCID: PMC6213443.
      View in: PubMed   Mentions: 5  
    45. Dissociating motor learning from recovery in exoskeleton training post-stroke. J Neuroeng Rehabil. 2018 10 05; 15(1):89. Schweighofer N, Wang C, Mottet D, Laffont I, Bakhti K, Reinkensmeyer DJ, Rémy-Néris O. PMID: 30290806; PMCID: PMC6173922.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    46. A comparison of seven different DTI-derived estimates of corticospinal tract structural characteristics in chronic stroke survivors. J Neurosci Methods. 2018 07 01; 304:66-75. Kim B, Fisher BE, Schweighofer N, Leahy RM, Haldar JP, Choi S, Kay DB, Gordon J, Winstein CJ. PMID: 29684462; PMCID: PMC5984168.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    47. Proximal arm non-use when reaching after a stroke. Neurosci Lett. 2017 Sep 14; 657:91-96. Bakhti KKA, Mottet D, Schweighofer N, Froger J, Laffont I. PMID: 28778806.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    48. Nonlinear mixed-effects model reveals a distinction between learning and performance in intensive reach training post-stroke. J Neuroeng Rehabil. 2017 03 17; 14(1):21. Park H, Schweighofer N. PMID: 28302158; PMCID: PMC5356348.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    49. The Roles of the Olivocerebellar Pathway in Motor Learning and Motor Control. A Consensus Paper. Cerebellum. 2017 02; 16(1):230-252. Lang EJ, Apps R, Bengtsson F, Cerminara NL, De Zeeuw CI, Ebner TJ, Heck DH, Jaeger D, Jörntell H, Kawato M, Otis TS, Ozyildirim O, Popa LS, Reeves AM, Schweighofer N, Sugihara I, Xiao J. PMID: 27193702; PMCID: PMC5116294.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    50. The duration of reaching movement is longer than predicted by minimum variance. J Neurophysiol. 2016 11 01; 116(5):2342-2345. Wang C, Xiao Y, Burdet E, Gordon J, Schweighofer N. PMID: 27559137; PMCID: PMC5110633.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    51. Computational neurorehabilitation: modeling plasticity and learning to predict recovery. J Neuroeng Rehabil. 2016 04 30; 13(1):42. Reinkensmeyer DJ, Burdet E, Casadio M, Krakauer JW, Kwakkel G, Lang CE, Swinnen SP, Ward NS, Schweighofer N. PMID: 27130577; PMCID: PMC4851823.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    52. Optimal Schedules in Multitask Motor Learning. Neural Comput. 2016 Apr; 28(4):667-85. Lee JY, Oh Y, Kim SS, Scheidt RA, Schweighofer N. PMID: 26890347; PMCID: PMC6555556.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    53. Neural Substrates Related to Motor Memory with Multiple Timescales in Sensorimotor Adaptation. PLoS Biol. 2015 Dec; 13(12):e1002312. Kim S, Ogawa K, Lv J, Schweighofer N, Imamizu H. PMID: 26645916; PMCID: PMC4672877.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    54. Daily update of motor predictions by physical activity. Sci Rep. 2015 Dec 03; 5:17933. Gueugneau N, Schweighofer N, Papaxanthis C. PMID: 26632341; PMCID: PMC4668580.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    55. Between-Trial Forgetting Due to Interference and Time in Motor Adaptation. PLoS One. 2015; 10(11):e0142963. Kim S, Oh Y, Schweighofer N. PMID: 26599075; PMCID: PMC4657926.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    56. Short-Duration and Intensive Training Improves Long-Term Reaching Performance in Individuals With Chronic Stroke. Neurorehabil Neural Repair. 2016 07; 30(6):551-61. Park H, Kim S, Winstein CJ, Gordon J, Schweighofer N. PMID: 26405046; PMCID: PMC4808509.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    57. Effort, success, and nonuse determine arm choice. J Neurophysiol. 2015 Jul; 114(1):551-9. Schweighofer N, Xiao Y, Kim S, Yoshioka T, Gordon J, Osu R. PMID: 25948869; PMCID: PMC4509397.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    58. Time-sensitive reorganization of the somatosensory cortex poststroke depends on interaction between Hebbian and homeoplasticity: a simulation study. J Neurophysiol. 2014 Dec 15; 112(12):3240-50. Bains AS, Schweighofer N. PMID: 25274347; PMCID: PMC4269712.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    59. Innovative technologies applied to sensorimotor rehabilitation after stroke. Ann Phys Rehabil Med. 2014 Nov; 57(8):543-551. Laffont I, Bakhti K, Coroian F, van Dokkum L, Mottet D, Schweighofer N, Froger J. PMID: 25261273.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    60. Infant exploratory learning: influence on leg joint coordination. PLoS One. 2014; 9(3):e91500. Sargent B, Schweighofer N, Kubo M, Fetters L. PMID: 24626202; PMCID: PMC3953400.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    61. Role of the olivo-cerebellar complex in motor learning and control. Front Neural Circuits. 2013; 7:94. Schweighofer N, Lang EJ, Kawato M. PMID: 23754983; PMCID: PMC3664774.
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    62. Solution to the inverse problem of estimating gap-junctional and inhibitory conductance in inferior olive neurons from spike trains by network model simulation. Neural Netw. 2013 Nov; 47:51-63. Onizuka M, Hoang H, Kawato M, Tokuda IT, Schweighofer N, Katori Y, Aihara K, Lang EJ, Toyama K. PMID: 23428796.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    63. Quantifying arm nonuse in individuals poststroke. Neurorehabil Neural Repair. 2013 Jun; 27(5):439-47. Han CE, Kim S, Chen S, Lai YH, Lee JY, Osu R, Winstein CJ, Schweighofer N. PMID: 23353185; PMCID: PMC3922644.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    64. Adaptive coupling of inferior olive neurons in cerebellar learning. Neural Netw. 2013 Nov; 47:42-50. Tokuda IT, Hoang H, Schweighofer N, Kawato M. PMID: 23337637.
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    65. Discriminant validity of a new measure of self-efficacy for reaching movements after stroke-induced hemiparesis. J Hand Ther. 2013 Apr-Jun; 26(2):116-22; quiz 123. Chen S, Lewthwaite R, Schweighofer N, Winstein CJ. PMID: 23123014.
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    66. Task-oriented rehabilitation robotics. Am J Phys Med Rehabil. 2012 Nov; 91(11 Suppl 3):S270-9. Schweighofer N, Choi Y, Winstein C, Gordon J. PMID: 23080042.
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    67. Use it and improve it or lose it: interactions between arm function and use in humans post-stroke. PLoS Comput Biol. 2012 Feb; 8(2):e1002343. Hidaka Y, Han CE, Wolf SL, Winstein CJ, Schweighofer N. PMID: 22761551; PMCID: PMC3385844.
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    68. Neural and personality correlates of individual differences related to the effects of acute tryptophan depletion on future reward evaluation. Neuropsychobiology. 2012; 65(2):55-64. Demoto Y, Okada G, Okamoto Y, Kunisato Y, Aoyama S, Onoda K, Munakata A, Nomura M, Tanaka SC, Schweighofer N, Doya K, Yamawaki S. PMID: 22222380.
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    69. Mechanisms of the contextual interference effect in individuals poststroke. J Neurophysiol. 2011 Nov; 106(5):2632-41. Schweighofer N, Lee JY, Goh HT, Choi Y, Kim SS, Stewart JC, Lewthwaite R, Winstein CJ. PMID: 21832031; PMCID: PMC3214116.
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    70. Feasibility of the adaptive and automatic presentation of tasks (ADAPT) system for rehabilitation of upper extremity function post-stroke. J Neuroeng Rehabil. 2011 Aug 03; 8:42. Choi Y, Gordon J, Park H, Schweighofer N. PMID: 21813010; PMCID: PMC3169456.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    71. Inter-individual discount factor differences in reward prediction are topographically associated with caudate activation. Exp Brain Res. 2011 Aug; 212(4):593-601. Onoda K, Okamoto Y, Kunisato Y, Aoyama S, Shishida K, Okada G, Tanaka SC, Schweighofer N, Yamaguchi S, Doya K, Yamawaki S. PMID: 21695536.
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    72. Cerebellar supervised learning revisited: biophysical modeling and degrees-of-freedom control. Curr Opin Neurobiol. 2011 Oct; 21(5):791-800. Kawato M, Kuroda S, Schweighofer N. PMID: 21665461.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    73. Neurological principles and rehabilitation of action disorders: computation, anatomy, and physiology (CAP) model. Neurorehabil Neural Repair. 2011 Jun; 25(5 Suppl):6S-20S. Frey SH, Fogassi L, Grafton S, Picard N, Rothwell JC, Schweighofer N, Corbetta M, Fitzpatrick SM. PMID: 21613534; PMCID: PMC4139496.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    74. Reward improves long-term retention of a motor memory through induction of offline memory gains. Curr Biol. 2011 Apr 12; 21(7):557-62. Abe M, Schambra H, Wassermann EM, Luckenbaugh D, Schweighofer N, Cohen LG. PMID: 21419628; PMCID: PMC3075334.
      View in: PubMed   Mentions: 129     Fields:    Translation:Humans
    75. Including prior knowledge for accurate and fast motor threshold estimation. Brain Stimul. 2011 Jan; 4(1):60-1. Qi F, Schweighofer N. PMID: 21255758.
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    76. Fast estimation of transcranial magnetic stimulation motor threshold. Brain Stimul. 2011 Jan; 4(1):50-7. Qi F, Wu AD, Schweighofer N. PMID: 21255756.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    77. Motor learning without doing: trial-by-trial improvement in motor performance during mental training. J Neurophysiol. 2010 Aug; 104(2):774-83. Gentili R, Han CE, Schweighofer N, Papaxanthis C. PMID: 20538766.
      View in: PubMed   Mentions: 69     Fields:    Translation:Humans
    78. The role of chaotic resonance in cerebellar learning. Neural Netw. 2010 Sep; 23(7):836-42. Tokuda IT, Han CE, Aihara K, Kawato M, Schweighofer N. PMID: 20494551.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    79. Neural correlates of the spacing effect in explicit verbal semantic encoding support the deficient-processing theory. Hum Brain Mapp. 2010 Apr; 31(4):645-59. Callan DE, Schweighofer N. PMID: 19882649; PMCID: PMC6871263.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    80. Serotonin affects association of aversive outcomes to past actions. J Neurosci. 2009 Dec 16; 29(50):15669-74. Tanaka SC, Shishida K, Schweighofer N, Okamoto Y, Yamawaki S, Doya K. PMID: 20016081; PMCID: PMC6666190.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    81. A functional threshold for long-term use of hand and arm function can be determined: predictions from a computational model and supporting data from the Extremity Constraint-Induced Therapy Evaluation (EXCITE) Trial. Phys Ther. 2009 Dec; 89(12):1327-36. Schweighofer N, Han CE, Wolf SL, Arbib MA, Winstein CJ. PMID: 19797304; PMCID: PMC2794477.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    82. Dual adaptation supports a parallel architecture of motor memory. J Neurosci. 2009 Aug 19; 29(33):10396-404. Lee JY, Schweighofer N. PMID: 19692614; PMCID: PMC2789989.
      View in: PubMed   Mentions: 110     Fields:    Translation:Humans
    83. Stroke rehabilitation reaches a threshold. PLoS Comput Biol. 2008 Aug 22; 4(8):e1000133. Han CE, Arbib MA, Schweighofer N. PMID: 18769588; PMCID: PMC2527783.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimals
    84. Performance-based adaptive schedules enhance motor learning. J Mot Behav. 2008 Jul; 40(4):273-80. Choi Y, Qi F, Gordon J, Schweighofer N. PMID: 18628104.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    85. Low-serotonin levels increase delayed reward discounting in humans. J Neurosci. 2008 Apr 23; 28(17):4528-32. Schweighofer N, Bertin M, Shishida K, Okamoto Y, Tanaka SC, Yamawaki S, Doya K. PMID: 18434531; PMCID: PMC6670945.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    86. Positive and negative modulation of word learning by reward anticipation. Hum Brain Mapp. 2008 Feb; 29(2):237-49. Callan DE, Schweighofer N. PMID: 17390317; PMCID: PMC6870695.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    87. Serotonin differentially regulates short- and long-term prediction of rewards in the ventral and dorsal striatum. PLoS One. 2007 Dec 19; 2(12):e1333. Tanaka SC, Schweighofer N, Asahi S, Shishida K, Okamoto Y, Yamawaki S, Doya K. PMID: 18091999; PMCID: PMC2129114.
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    88. Multiple model-based reinforcement learning explains dopamine neuronal activity. Neural Netw. 2007 Aug; 20(6):668-75. Bertin M, Schweighofer N, Doya K. PMID: 17611074.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    89. Serotonin and the evaluation of future rewards: theory, experiments, and possible neural mechanisms. Ann N Y Acad Sci. 2007 May; 1104:289-300. Schweighofer N, Tanaka SC, Doya K. PMID: 17360806.
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    90. Humans can adopt optimal discounting strategy under real-time constraints. PLoS Comput Biol. 2006 Nov 10; 2(11):e152. Schweighofer N, Shishida K, Han CE, Okamoto Y, Tanaka SC, Yamawaki S, Doya K. PMID: 17096592; PMCID: PMC1635539.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    91. Kinematic features of movement tunes perception and action coupling. Behav Brain Res. 2006 Apr 25; 169(1):75-82. Pozzo T, Papaxanthis C, Petit JL, Schweighofer N, Stucchi N. PMID: 16430976.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    92. Computational motor control in humans and robots. Curr Opin Neurobiol. 2005 Dec; 15(6):675-82. Schaal S, Schweighofer N. PMID: 16271466.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    93. Chaos may enhance information transmission in the inferior olive. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4655-60. Schweighofer N, Doya K, Fukai H, Chiron JV, Furukawa T, Kawato M. PMID: 15070773; PMCID: PMC384802.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    94. Cerebellar aminergic neuromodulation: towards a functional understanding. Brain Res Brain Res Rev. 2004 Mar; 44(2-3):103-16. Schweighofer N, Doya K, Kuroda S. PMID: 15003388.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimals
    95. Meta-learning in reinforcement learning. Neural Netw. 2003 Jan; 16(1):5-9. Schweighofer N, Doya K. PMID: 12576101.
      View in: PubMed   Mentions: 26     Fields:    
    96. Exploration of signal transduction pathways in cerebellar long-term depression by kinetic simulation. J Neurosci. 2001 Aug 01; 21(15):5693-702. Kuroda S, Schweighofer N, Kawato M. PMID: 11466441; PMCID: PMC6762656.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    97. Unsupervised learning of granule cell sparse codes enhances cerebellar adaptive control. Neuroscience. 2001; 103(1):35-50. Schweighofer N, Doya K, Lay F. PMID: 11311786.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    98. Diffusion of nitric oxide can facilitate cerebellar learning: A simulation study. Proc Natl Acad Sci U S A. 2000 Sep 12; 97(19):10661-5. Schweighofer N, Ferriol G. PMID: 10984547; PMCID: PMC27081.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    99. Cerebellar learning of accurate predictive control for fast-reaching movements. Biol Cybern. 2000 Apr; 82(4):321-33. Spoelstra J, Schweighofer N, Arbib MA. PMID: 10804064.
      View in: PubMed   Mentions: 16     Fields:    
    100. Electrophysiological properties of inferior olive neurons: A compartmental model. J Neurophysiol. 1999 Aug; 82(2):804-17. Schweighofer N, Doya K, Kawato M. PMID: 10444678.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    101. A model of activity-dependent formation of cerebellar microzones. Biol Cybern. 1998 Aug; 79(2):97-107. Schweighofer N. PMID: 9791930.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    102. Role of the cerebellum in reaching movements in humans. II. A neural model of the intermediate cerebellum. Eur J Neurosci. 1998 Jan; 10(1):95-105. Schweighofer N, Spoelstra J, Arbib MA, Kawato M. PMID: 9753117.
      View in: PubMed   Mentions: 32  Translation:HumansCells
    103. A model of cerebellar metaplasticity. Learn Mem. 1998 Jan-Feb; 4(5):421-8. Schweighofer N, Arbib MA. PMID: 10701881.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    104. Role of the cerebellum in reaching movements in humans. I. Distributed inverse dynamics control. Eur J Neurosci. 1998 Jan; 10(1):86-94. Schweighofer N, Arbib MA, Kawato M. PMID: 9753116.
      View in: PubMed   Mentions: 48  Translation:HumansCells
    105. A model of the cerebellum in adaptive control of saccadic gain. II. Simulation results. Biol Cybern. 1996 Jul; 75(1):29-36. Schweighofer N, Arbib MA, Dominey PF. PMID: 8765654.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    106. A model of the cerebellum in adaptive control of saccadic gain. I. The model and its biological substrate. Biol Cybern. 1996 Jul; 75(1):19-28. Schweighofer N, Arbib MA, Dominey PF. PMID: 8765653.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
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