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Andrei Irimia, PhD

Title(s)Assistant Professor of Gerontology, Biomedical Engineering and Neuroscience
Phone+1 213 740 1710
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    Collapse Research 
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    Effects of blood-brain barrier disruption upon white matter connectivity subsequent to traumatic brain injury
    NIH/NINDS R01NS100973Mar 15, 2017 - Feb 28, 2022
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Irimia A, Maher AS, Rostowsky KA, Chowdhury NF, Hwang DH, Law EM. Brain Segmentation From Computed Tomography of Healthy Aging and Geriatric Concussion at Variable Spatial Resolutions. Front Neuroinform. 2019; 13:9. PMID: 30936828.
      View in: PubMed
    2. Irimia A, Lei X, Torgerson CM, Jacokes ZJ, Abe S, Van Horn JD. Support Vector Machines, Multidimensional Scaling and Magnetic Resonance Imaging Reveal Structural Brain Abnormalities Associated With the Interaction Between Autism Spectrum Disorder and Sex. Front Comput Neurosci. 2018; 12:93. PMID: 30534065.
      View in: PubMed
    3. Rostowsky KA, Maher AS, Irimia A. Macroscale White Matter Alterations Due to Traumatic Cerebral Microhemorrhages Are Revealed by Diffusion Tensor Imaging. Front Neurol. 2018; 9:948. PMID: 30483210.
      View in: PubMed
    4. Maher AS, Rostowsky KA, Chowdhury NF, Irimia A. Neuroinformatics and Analysis of Connectomic Alterations Due to Cerebral Microhemorrhages in Geriatric Mild Neurotrauma. ACM BCB. 2018 Aug-Sep; 2018:165-171. PMID: 30687848.
      View in: PubMed
    5. Hull JV, Dokovna LB, Jacokes ZJ, Torgerson CM, Irimia A, Van Horn JD. Corrigendum: Resting-State Functional Connectivity in Autism Spectrum Disorders: A Review. Front Psychiatry. 2018; 9:268. PMID: 29962977.
      View in: PubMed
    6. Irimia A, Van Horn JD, Vespa PM. Cerebral microhemorrhages due to traumatic brain injury and their effects on the aging human brain. Neurobiol Aging. 2018 06; 66:158-164. PMID: 29579686.
      View in: PubMed
    7. Irimia A, Goh SM, Wade AC, Patel K, Vespa PM, Van Horn JD. Traumatic Brain Injury Severity, Neuropathophysiology, and Clinical Outcome: Insights from Multimodal Neuroimaging. Front Neurol. 2017; 8:530. PMID: 29051745.
      View in: PubMed
    8. Hinojosa-Rodríguez M, Harmony T, Carrillo-Prado C, Van Horn JD, Irimia A, Torgerson C, Jacokes Z. Clinical neuroimaging in the preterm infant: Diagnosis and prognosis. Neuroimage Clin. 2017; 16:355-368. PMID: 28861337.
      View in: PubMed
    9. Irimia A, Wei S, Lu N, Moore CM, Kennedy DN. Mobile Monitoring of Traumatic Brain Injury in Older Adults: Challenges and Opportunities. Neuroinformatics. 2017 07; 15(3):227-230. PMID: 28748392.
      View in: PubMed
    10. Van Horn JD, Irimia A, Torgerson CM, Bhattrai A, Jacokes Z, Vespa PM. Mild cognitive impairment and structural brain abnormalities in a sexagenarian with a history of childhood traumatic brain injury. J Neurosci Res. 2018 Apr; 96(4):652-660. PMID: 28543689.
      View in: PubMed
    11. Irimia A, Torgerson CM, Jacokes ZJ, Van Horn JD. The connectomes of males and females with autism spectrum disorder have significantly different white matter connectivity densities. Sci Rep. 2017 Apr 11; 7:46401. PMID: 28397802.
      View in: PubMed
    12. Hull JV, Dokovna LB, Jacokes ZJ, Torgerson CM, Irimia A, Van Horn JD. Resting-State Functional Connectivity in Autism Spectrum Disorders: A Review. Front Psychiatry. 2016; 7:205. PMID: 28101064.
      View in: PubMed
    13. Palacios EM, Martin AJ, Boss MA, Ezekiel F, Chang YS, Yuh EL, Vassar MJ, Schnyer DM, MacDonald CL, Crawford KL, Irimia A, Toga AW, Mukherjee P. Toward Precision and Reproducibility of Diffusion Tensor Imaging: A Multicenter Diffusion Phantom and Traveling Volunteer Study. AJNR Am J Neuroradiol. 2017 Mar; 38(3):537-545. PMID: 28007768.
      View in: PubMed
    14. Van Horn JD, Bhattrai A, Irimia A. Multimodal Imaging of Neurometabolic Pathology due to Traumatic Brain Injury. Trends Neurosci. 2017 01; 40(1):39-59. PMID: 27939821.
      View in: PubMed
    15. Wang B, Prastawa M, Irimia A, Saha A, Liu W, Goh SY, Vespa PM, Van Horn JD, Gerig G. Modeling 4D Pathological Changes by Leveraging Normative Models. Comput Vis Image Underst. 2016 10; 151:3-13. PMID: 27818606.
      View in: PubMed
    16. Irimia A, Van Horn JD. Scale-Dependent Variability and Quantitative Regimes in Graph-Theoretic Representations of Human Cortical Networks. Brain Connect. 2016 Mar; 6(2):152-63. PMID: 26596775; PMCID: PMC4779965 [Available on 03/01/17].
    17. Irimia A, Torgerson CM, Goh SY, Van Horn JD. Statistical estimation of physiological brain age as a descriptor of senescence rate during adulthood. Brain Imaging Behav. 2015 Dec; 9(4):678-89. PMID: 25376330; PMCID: PMC4424195 [Available on 12/01/16].
    18. Irimia A, Van Horn JD. Functional neuroimaging of traumatic brain injury: advances and clinical utility. Neuropsychiatr Dis Treat. 2015; 11:2355-65. PMID: 26396520; PMCID: PMC4576900.
    19. Labus JS, Van Horn JD, Gupta A, Alaverdyan M, Torgerson C, Ashe-McNalley C, Irimia A, Hong JY, Naliboff B, Tillisch K, Mayer EA. Multivariate morphological brain signatures predict patients with chronic abdominal pain from healthy control subjects. Pain. 2015 Aug; 156(8):1545-54. PMID: 25906347; PMCID: PMC4504800.
    20. Irimia A, Labus JS, Torgerson CM, Van Horn JD, Mayer EA. Altered viscerotopic cortical innervation in patients with irritable bowel syndrome. Neurogastroenterol Motil. 2015 Aug; 27(8):1075-81. PMID: 25952540.
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    21. Frohlich J, Irimia A, Jeste SS. Trajectory of frequency stability in typical development. Brain Imaging Behav. 2015 Mar; 9(1):5-18. PMID: 25501709.
      View in: PubMed
    22. Goh SY, Irimia A, Torgerson CM, Tubi MA, Real CR, Hanley DF, Martin NA, Vespa PM, Van Horn JD. Longitudinal quantification and visualization of intracerebral haemorrhage using multimodal magnetic resonance and diffusion tensor imaging. Brain Inj. 2015; 29(4):438-45. PMID: 25518865; PMCID: PMC4440338.
    23. Irimia A, Van Horn JD. Epileptogenic focus localization in treatment-resistant post-traumatic epilepsy. J Clin Neurosci. 2015 Apr; 22(4):627-31. PMID: 25542591; PMCID: PMC4380645.
    24. Torgerson CM, Irimia A, Goh SY, Van Horn JD. The DTI connectivity of the human claustrum. Hum Brain Mapp. 2015 Mar; 36(3):827-38. PMID: 25339630.
      View in: PubMed
    25. Irimia A, Goh SY, Torgerson CM, Vespa P, Van Horn JD. Structural and connectomic neuroimaging for the personalized study of longitudinal alterations in cortical shape, thickness and connectivity after traumatic brain injury. J Neurosurg Sci. 2014 Sep; 58(3):129-44. PMID: 24844173; PMCID: PMC4158854.
    26. Wang B, Liu W, Prastawa M, Irimia A, Vespa PM, van Horn JD, Fletcher PT, Gerig G. 4D ACTIVE CUT: AN INTERACTIVE TOOL FOR PATHOLOGICAL ANATOMY MODELING. Proc IEEE Int Symp Biomed Imaging. 2014 Apr; 2014:529-532. PMID: 25356193.
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    27. Goh SY, Irimia A, Torgerson CM, Horn JD. Neuroinformatics challenges to the structural, connectomic, functional and electrophysiological multimodal imaging of human traumatic brain injury. Front Neuroinform. 2014; 8:19. PMID: 24616696.
      View in: PubMed
    28. Irimia A, Erhart MJ, Brown TT. Variability of magnetoencephalographic sensor sensitivity measures as a function of age, brain volume and cortical area. Clin Neurophysiol. 2014 Oct; 125(10):1973-84. PMID: 24589347; PMCID: PMC4133309.
    29. Irimia A, Van Horn JD. Systematic network lesioning reveals the core white matter scaffold of the human brain. Front Hum Neurosci. 2014; 8:51. PMID: 24574993; PMCID: PMC3920080.
    30. Wang B, Prastawa M, Irimia A, Chambers MC, Sadeghi N, Vespa PM, van Horn JD, Gerig G. ANALYZING IMAGING BIOMARKERS FOR TRAUMATIC BRAIN INJURY USING 4D MODELING OF LONGITUDINAL MRI. Proc IEEE Int Symp Biomed Imaging. 2013 Dec 31; 2013:1392-1395. PMID: 24443697.
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    31. Wright MJ, McArthur DL, Alger JR, Van Horn J, Irimia A, Filippou M, Glenn TC, Hovda DA, Vespa P. Early metabolic crisis-related brain atrophy and cognition in traumatic brain injury. Brain Imaging Behav. 2013 Sep; 7(3):307-15. PMID: 23636971; PMCID: PMC4172457.
    32. Lou Y, Irimia A, Vela PA, Chambers MC, Van Horn JD, Vespa PM, Tannenbaum AR. Multimodal deformable registration of traumatic brain injury MR volumes via the Bhattacharyya distance. IEEE Trans Biomed Eng. 2013 Sep; 60(9):2511-20. PMID: 23962986; PMCID: PMC4000558.
    33. Irimia A, Goh SY, Torgerson CM, Stein NR, Chambers MC, Vespa PM, Van Horn JD. Electroencephalographic inverse localization of brain activity in acute traumatic brain injury as a guide to surgery, monitoring and treatment. Clin Neurol Neurosurg. 2013 Oct; 115(10):2159-65. PMID: 24011495; PMCID: PMC3807758.
    34. Irimia A, Goh SY, Torgerson CM, Chambers MC, Kikinis R, Van Horn JD. Forward and inverse electroencephalographic modeling in health and in acute traumatic brain injury. Clin Neurophysiol. 2013 Nov; 124(11):2129-45. PMID: 23746499; PMCID: PMC3805748.
    35. Torgerson CM, Irimia A, Leow AD, Bartzokis G, Moody TD, Jennings RG, Alger JR, Van Horn JD, Altshuler LL. DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects. Brain Imaging Behav. 2013 Jun; 7(2):129-39. PMID: 23070746; PMCID: PMC3572298.
    36. Wang B, Prastawa M, Saha A, Awate SP, Irimia A, Chambers MC, Vespa PM, Van Horn JD, Pascucci V, Gerig G. Modeling 4D Changes in Pathological Anatomy using Domain Adaptation: Analysis of TBI Imaging using a Tumor Database. Multimodal Brain Image Anal (2013). 2013; 8159:31-39. PMID: 25346953.
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    37. Irimia A, Van Horn JD. The structural, connectomic and network covariance of the human brain. Neuroimage. 2013 Feb 01; 66:489-99. PMID: 23116816; PMCID: PMC3586751.
    38. Kovacevic S, Azma S, Irimia A, Sherfey J, Halgren E, Marinkovic K. Theta oscillations are sensitive to both early and late conflict processing stages: effects of alcohol intoxication. PLoS One. 2012; 7(8):e43957. PMID: 22952823; PMCID: PMC3428276.
    39. Irimia A, Wang B, Aylward SR, Prastawa MW, Pace DF, Gerig G, Hovda DA, Kikinis R, Vespa PM, Van Horn JD. Neuroimaging of structural pathology and connectomics in traumatic brain injury: Toward personalized outcome prediction. Neuroimage Clin. 2012; 1(1):1-17. PMID: 24179732.
      View in: PubMed
    40. Van Horn JD, Irimia A, Torgerson CM, Chambers MC, Kikinis R, Toga AW. Mapping connectivity damage in the case of Phineas Gage. PLoS One. 2012; 7(5):e37454. PMID: 22616011.
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    41. Wang B, Prastawa M, Irimia A, Chambers MC, Vespa PM, Van Horn JD, Gerig G. A Patient-Specific Segmentation Framework for Longitudinal MR Images of Traumatic Brain Injury. Proc SPIE Int Soc Opt Eng. 2012 Mar 23; 8314:831402. PMID: 24465115.
      View in: PubMed
    42. Irimia A, Chambers MC, Torgerson CM, Filippou M, Hovda DA, Alger JR, Gerig G, Toga AW, Vespa PM, Kikinis R, Van Horn JD. Patient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injury. Front Neurol. 2012; 3:10. PMID: 22363313; PMCID: PMC3275792.
    43. Irimia A, Chambers MC, Torgerson CM, Van Horn JD. Circular representation of human cortical networks for subject and population-level connectomic visualization. Neuroimage. 2012 Apr 02; 60(2):1340-51. PMID: 22305988; PMCID: PMC3594415.
    44. Wang B, Prastawa M, Awate SP, Irimia A, Chambers MC, Vespa PM, van Horn JD, Gerig G. SEGMENTATION OF SERIAL MRI OF TBI PATIENTS USING PERSONALIZED ATLAS CONSTRUCTION AND TOPOLOGICAL CHANGE ESTIMATION. Proc IEEE Int Symp Biomed Imaging. 2012; 1152-1155. PMID: 23999192.
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    45. Irimia A, Chambers MC, Alger JR, Filippou M, Prastawa MW, Wang B, Hovda DA, Gerig G, Toga AW, Kikinis R, Vespa PM, Van Horn JD. Comparison of acute and chronic traumatic brain injury using semi-automatic multimodal segmentation of MR volumes. J Neurotrauma. 2011 Nov; 28(11):2287-306. PMID: 21787171; PMCID: PMC3218448.
    46. Irimia A, Van Horn JD, Halgren E. Source cancellation profiles of electroencephalography and magnetoencephalography. Neuroimage. 2012 Feb 01; 59(3):2464-74. PMID: 21959078; PMCID: PMC3254784.
    47. Niethammer M, Hart GL, Pace DF, Vespa PM, Irimia A, Van Horn JD, Aylward SR. Geometric metamorphosis. Med Image Comput Comput Assist Interv. 2011; 14(Pt 2):639-46. PMID: 21995083; PMCID: PMC3719851.
    48. Halgren E, Sherfey J, Irimia A, Dale AM, Marinkovic K. Sequential temporo-fronto-temporal activation during monitoring of the auditory environment for temporal patterns. Hum Brain Mapp. 2011 Aug; 32(8):1260-76. PMID: 20665718; PMCID: PMC2970649.
    49. Irimia A, Swinney KR, Wikswo JP. Partial independence of bioelectric and biomagnetic fields and its implications for encephalography and cardiography. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 May; 79(5 Pt 1):051908. PMID: 19518481.
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    50. Irimia A, Richards WO, Bradshaw LA. Comparison of conventional filtering and independent component analysis for artifact reduction in simultaneous gastric EMG and magnetogastrography from porcines. IEEE Trans Biomed Eng. 2009 Nov; 56(11):2611-8. PMID: 19398400.
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    51. Bradshaw LA, Irimia A, Sims JA, Richards WO. Biomagnetic signatures of uncoupled gastric musculature. Neurogastroenterol Motil. 2009 Jul; 21(7):778-e50. PMID: 19222760.
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    52. Irimia A, Wikswo JP. Gastrointestinal arrhythmias are associated with statistically significant fluctuations in systemic information dimension. Physiol Meas. 2008 May; 29(5):N33-40. PMID: 18427160.
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    53. Bradshaw LA, Irimia A, Sims JA, Gallucci MR, Palmer RL, Richards WO. Biomagnetic characterization of spatiotemporal parameters of the gastric slow wave. Neurogastroenterol Motil. 2006 Aug; 18(8):619-31. PMID: 16918726.
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    54. Irimia A, Cheng LK, Buist ML, Pullan AJ, Bradshaw LA. An integrative software package for gastrointestinal biomagnetic data acquisition and analysis using SQUID magnetometers. Comput Methods Programs Biomed. 2006 Aug; 83(2):83-94. PMID: 16857291.
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    55. Irimia A, Richards WO, Bradshaw LA. Magnetogastrographic detection of gastric electrical response activity in humans. Phys Med Biol. 2006 Mar 07; 51(5):1347-60. PMID: 16481699.
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    56. Irimia A, Bradshaw LA. Artifact reduction in magnetogastrography using fast independent component analysis. Physiol Meas. 2005 Dec; 26(6):1059-73. PMID: 16311453.
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    57. Irimia A, Bradshaw LA. Ellipsoidal electrogastrographic forward modelling. Phys Med Biol. 2005 Sep 21; 50(18):4429-44. PMID: 16148402.
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    58. Irimia A, Beauchamp JJ, Bradshaw LA. Theoretical and computational multiple regression study of gastric electrical activity using dipole tracing from magnetic field measurements. J Biol Phys. 2004 Sep; 30(3):239-59. PMID: 23345871.
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    59. Irimia A, Bradshaw LA. Theoretical and computational methods for the noninvasive detection of gastric electrical source coupling. Phys Rev E Stat Nonlin Soft Matter Phys. 2004 May; 69(5 Pt 1):051920. PMID: 15244860.
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    60. Irimia A, Bradshaw LA. Theoretical ellipsoidal model of gastric electrical control activity propagation. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Nov; 68(5 Pt 1):051905. PMID: 14682818.
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