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    Thomas D Coates, MD

    TitleProfessor of Pediatrics
    SchoolKeck School of Medicine of USC
    DepartmentPediatrics
    AddressCHL Mail Stop 54
    Off Campus
    Los Angeles California 90089
    Phone+1 323 361 2352
    Emailtcoates@chla.usc.edu
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      Other Positions
      TitleSection Head of Hematology

      TitleDirector of Sickle/Hemoglobinopathy Program


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      I primarily work in two areas of basic and translational research: 1) the role of inflammation in the genesis of vascular disease in sickle cell disease; 2) the detection and management of transfusion related iron overload. Our research employs various engineering-intensive methodologies (MRI, laser Doppler flow, digital image analysis, signal processing) to explore the basic mechanisms of sickle cell disease and to measure the effect of various treatment modalities. We use direct measures of microvascular blood flow to monitor the process of vasoocclusion and relate it to simultaneous measures of autonomic nervous system function. These methodologies translate in measurements that can be used to follow patients clinically. In collaboration with members of the Cardiology, Pulmonology, and Radiology Departments at Children’s Hospital Los Angeles, the Departments of Biomedical Engineering and Physiology/Biophysics at the Keck School of Medicine, we devised methods to measure the sickling process in human sickle cell subjects and relate these measurements to clinical factors that modulate disease severity.


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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Coloigner J, Phlypo R, Coates T, Lepore N, Wood JC. Graph Lasso-Based Test for Evaluating Functional Brain Connectivity in Sickle Cell Disease. Brain Connect. 2017 Sep; 7(7):443-453. PMID: 28747064.
        View in: PubMed
      2. Bhatt RR, Martin SR, Evans S, Lung K, Coates T, Zeltzer LK, Tsao JC. The effect of hypnosis on pain and peripheral blood flow in sickle-cell disease: a pilot study. J Pain Res. 2017; 10:1635-1644. PMID: 28769584.
        View in: PubMed
      3. Khaleel M, Puliyel M, Shah P, Sunwoo J, Kato RM, Chalacheva P, Thuptimdang W, Detterich J, Wood JC, Tsao J, Zeltzer L, Sposto R, Khoo MCK, Coates T. Individuals with sickle cell disease have a significantly greater vasoconstriction response to thermal pain than controls and have significant vasoconstriction in response to anticipation of pain. Am J Hematol. 2017 Jul 13. PMID: 28707371.
        View in: PubMed
      4. Doyle EK, Toy K, Valdez B, Chia JM, Coates T, Wood JC. Ultra-short echo time images quantify high liver iron. Magn Reson Med. 2017 Jun 22. PMID: 28643355.
        View in: PubMed
      5. Chalacheva P, Khaleel M, Sunwoo J, Shah P, Detterich JA, Kato RM, Thuptimdang W, Meiselman HJ, Sposto R, Tsao J, Wood JC, Zeltzer L, Coates T, Khoo MCK. Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease. PLoS One. 2017; 12(5):e0178353. PMID: 28542469.
        View in: PubMed
      6. Choi S, Bush AM, Borzage MT, Joshi AA, Mack WJ, Coates T, Leahy RM, Wood JC. Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients. Neuroimage Clin. 2017; 15:239-246. PMID: 28540180.
        View in: PubMed
      7. Angelucci E, Pilo F, Coates T. Transplantation in thalassemia: Revisiting the Pesaro risk factors 25 years later. Am J Hematol. 2017 May; 92(5):411-413. PMID: 28181283.
        View in: PubMed
      8. Coates T, Wood JC. How we manage iron overload in sickle cell patients. Br J Haematol. 2017 Jun; 177(5):703-716. PMID: 28295188.
        View in: PubMed
      9. Daniels J, Maleke K, Lane T, Struthers H, McIntyre J, Kegeles S, Moore A, Coates T. Learning to Live With HIV in the Rural Townships: A Photovoice Study of Men Who Have Sex With Men Living With HIV in Mpumalanga, South Africa. J Assoc Nurses AIDS Care. 2017 May - Jun; 28(3):408-421. PMID: 28279587.
        View in: PubMed
      10. Paulukonis ST, Feuchtbaum LB, Coates T, Neumayr LD, Treadwell MJ, Vichinsky EP, Hulihan MM. Emergency department utilization by Californians with sickle cell disease, 2005-2014. Pediatr Blood Cancer. 2017 Jun; 64(6). PMID: 28000344.
        View in: PubMed
      11. Daniels J, Komarek A, Forgreive B, Pahl K, Stafford S, Bruns LC, Coates T. Shout-It-Now: A Mobile HCT Model Employing Technology and Edutainment in South Africa. J Int Assoc Provid AIDS Care. 2017 Sep/Oct; 16(5):506-511. PMID: 27903950.
        View in: PubMed
      12. Coates T. Unchanneling cardiac iron in humans. Blood. 2016 Sep 22; 128(12):1538-40. PMID: 27658696.
        View in: PubMed
      13. Bush A, Borzage M, Detterich J, Kato RM, Meiselman HJ, Coates T, Wood JC. Empirical model of human blood transverse relaxation at 3?T improves MRI T2 oximetry. Magn Reson Med. 2017 Jun; 77(6):2364-2371. PMID: 27385283.
        View in: PubMed
      14. Bush AM, Borzage MT, Choi S, Václavu L, Tamrazi B, Nederveen AJ, Coates T, Wood JC. Determinants of resting cerebral blood flow in sickle cell disease. Am J Hematol. 2016 Sep; 91(9):912-7. PMID: 27263497; PMCID: PMC4987198 [Available on 09/01/17].
      15. Wang L, Valderramos SG, Wu A, Ouyang S, Li C, Brasil P, Bonaldo M, Coates T, Nielsen-Saines K, Jiang T, Aliyari R, Cheng G. From Mosquitos to Humans: Genetic Evolution of Zika Virus. Cell Host Microbe. 2016 May 11; 19(5):561-5. PMID: 27091703.
        View in: PubMed
      16. Coates T, Carson S, Wood JC, Berdoukas V. Management of iron overload in hemoglobinopathies: what is the appropriate target iron level? Ann N Y Acad Sci. 2016 Mar; 1368(1):95-106. PMID: 27186942.
        View in: PubMed
      17. Borzage MT, Bush AM, Choi S, Nederveen AJ, Václavu L, Coates T, Wood JC. Predictors of cerebral blood flow in patients with and without anemia. J Appl Physiol (1985). 2016 Apr 15; 120(8):976-81. PMID: 26796758; PMCID: PMC4835904 [Available on 04/15/17].
      18. Reitman AJ, Coates T, Freyer DR. Early Cardiac Iron Overload in a Child on Treatment of Acute Lymphoblastic Leukemia. Pediatrics. 2015 Sep; 136(3):e697-700. PMID: 26283784.
        View in: PubMed
      19. Berdoukas V, Coates T, Cabantchik ZI. Iron and oxidative stress in cardiomyopathy in thalassemia. Free Radic Biol Med. 2015 Nov; 88(Pt A):3-9. PMID: 26216855.
        View in: PubMed
      20. Chalacheva P, Kato RM, Sangkatumvong S, Detterich J, Bush A, Wood JC, Meiselman H, Coates T, Khoo MC. Autonomic responses to cold face stimulation in sickle cell disease: a time-varying model analysis. Physiol Rep. 2015 Jul 14; 3(7). PMID: 26177958; PMCID: PMC4552538.
      21. Detterich JA, Kato RM, Rabai M, Meiselman HJ, Coates T, Wood JC. Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease. Blood. 2015 Aug 06; 126(6):703-10. PMID: 26036801; PMCID: PMC4528063.
      22. Huang KE, Mittelman SD, Coates T, Geffner ME, Wood JC. A significant proportion of thalassemia major patients have adrenal insufficiency detectable on provocative testing. J Pediatr Hematol Oncol. 2015 Jan; 37(1):54-9. PMID: 24942024; PMCID: PMC4393555.
      23. Mainous AG, Tanner RJ, Coates T, Baker R. Prediabetes, elevated iron and all-cause mortality: a cohort study. BMJ Open. 2014 Dec 11; 4(12):e006491. PMID: 25500370; PMCID: PMC4265136.
      24. Puliyel M, Mainous AG, Berdoukas V, Coates T. Iron toxicity and its possible association with treatment of Cancer: lessons from hemoglobinopathies and rare, transfusion-dependent anemias. Free Radic Biol Med. 2015 Feb; 79:343-51. PMID: 25463277.
        View in: PubMed
      25. Paulukonis ST, Harris WT, Coates T, Neumayr L, Treadwell M, Vichinsky E, Feuchtbaum LB. Population based surveillance in sickle cell disease: methods, findings and implications from the California registry and surveillance system in hemoglobinopathies project (RuSH). Pediatr Blood Cancer. 2014 Dec; 61(12):2271-6. PMID: 25176145.
        View in: PubMed
      26. Mainous AG, Tanner RJ, Hulihan MM, Amaya M, Coates T. The impact of chelation therapy on survival in transfusional iron overload: a meta-analysis of myelodysplastic syndrome. Br J Haematol. 2014 Dec; 167(5):720-3. PMID: 25048454; PMCID: PMC4991026.
      27. Young SD, Holloway I, Jaganath D, Rice E, Westmoreland D, Coates T. Project HOPE: online social network changes in an HIV prevention randomized controlled trial for African American and Latino men who have sex with men. Am J Public Health. 2014 Sep; 104(9):1707-12. PMID: 25033137; PMCID: PMC4151951.
      28. Daniels J, Komárek A, Makusha T, Van Heerden A, Gray G, Chingono A, Mbwambo JK, Coates T, Richter L. Effects of a community intervention on HIV prevention behaviors among men who experienced childhood sexual or physical abuse in four African settings: findings from NIMH Project Accept (HPTN 043). PLoS One. 2014; 9(6):e99643. PMID: 24926999; PMCID: PMC4057211.
      29. Green ST, Martin MB, Haines D, Carson S, Coates T, Oliveros O, Gerstenberger E, Trachtenberg F, Kwiatkowski JL. Variance of pain prevalence and associated severity during the transfusion cycle of adult thalassaemia patients. Br J Haematol. 2014 Sep; 166(5):797-800. PMID: 24805301; PMCID: PMC4134713.
      30. Meloni A, Puliyel M, Pepe A, Berdoukas V, Coates T, Wood JC. Cardiac iron overload in sickle-cell disease. Am J Hematol. 2014 Jul; 89(7):678-83. PMID: 24664847.
        View in: PubMed
      31. Coates T. Physiology and pathophysiology of iron in hemoglobin-associated diseases. Free Radic Biol Med. 2014 Jul; 72:23-40. PMID: 24726864; PMCID: PMC4940047.
      32. Koblin BA, Mansergh G, Chesney M, Coates T. Moving the bar to the right place: positioning interventions in HIV prevention. AIDS Behav. 2014 Apr; 18(4):634-7. PMID: 24057930; PMCID: PMC3962710.
      33. Coates T. Bad liver and a broken heart. Blood. 2014 Mar 06; 123(10):1434-6. PMID: 24627546.
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      34. Puliyel M, Sposto R, Berdoukas VA, Hofstra TC, Nord A, Carson S, Wood J, Coates T. Ferritin trends do not predict changes in total body iron in patients with transfusional iron overload. Am J Hematol. 2014 Apr; 89(4):391-4. PMID: 24347294.
        View in: PubMed
      35. Williams DA, Bennett C, Bertuch A, Bessler M, Coates T, Corey S, Dror Y, Huang J, Lipton J, Olson TS, Reiss UM, Rogers ZR, Sieff C, Vlachos A, Walkovich K, Wang W, Shimamura A. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatr Blood Cancer. 2014 May; 61(5):869-74. PMID: 24285674; PMCID: PMC4280184.
      36. Laeyendecker O, Kulich M, Donnell D, Komárek A, Omelka M, Mullis CE, Szekeres G, Piwowar-Manning E, Fiamma A, Gray RH, Lutalo T, Morrison CS, Salata RA, Chipato T, Celum C, Kahle EM, Taha TE, Kumwenda NI, Karim QA, Naranbhai V, Lingappa JR, Sweat MD, Coates T, Eshleman SH. Development of methods for cross-sectional HIV incidence estimation in a large, community randomized trial. PLoS One. 2013; 8(11):e78818. PMID: 24236054; PMCID: PMC3827276.
      37. van Rooyen H, McGrath N, Chirowodza A, Joseph P, Fiamma A, Gray G, Richter L, Coates T. Mobile VCT: reaching men and young people in urban and rural South African pilot studies (NIMH Project Accept, HPTN 043). AIDS Behav. 2013 Nov; 17(9):2946-53. PMID: 23142856; PMCID: PMC3597746.
      38. Young SD, Cumberland WG, Lee SJ, Jaganath D, Szekeres G, Coates T. Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial. Ann Intern Med. 2013 Sep 03; 159(5):318-24. PMID: 24026317; PMCID: PMC3879120.
      39. Berdoukas V, Nord A, Carson S, Puliyel M, Hofstra T, Wood J, Coates T. Tissue iron evaluation in chronically transfused children shows significant levels of iron loading at a very young age. Am J Hematol. 2013 Nov; 88(11):E283-5. PMID: 23861216.
        View in: PubMed
      40. Wanyenze RK, Kamya MR, Fatch R, Mayanja-Kizza H, Baveewo S, Szekeres G, Bangsberg DR, Coates T, Hahn JA. Abbreviated HIV counselling and testing and enhanced referral to care in Uganda: a factorial randomised controlled trial. Lancet Glob Health. 2013 Sep; 1(3):e137-45. PMID: 25104262; PMCID: PMC4129546.
      41. Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA. Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME). Transfusion. 2014 Apr; 54(4):972-81; quiz 971. PMID: 23889533; PMCID: PMC4410835.
      42. Young SD, Szekeres G, Coates T. Sexual risk and HIV prevention behaviours among African-American and Latino MSM social networking users. Int J STD AIDS. 2013 Aug; 24(8):643-9. PMID: 23970575; PMCID: PMC3855428.
      43. Laeyendecker O, Piwowar-Manning E, Fiamma A, Kulich M, Donnell D, Bassuk D, Mullis CE, Chin C, Swanson P, Hackett J, Clarke W, Marzinke M, Szekeres G, Gray G, Richter L, Alexandre MW, Chariyalertsak S, Chingono A, Celentano DD, Morin SF, Sweat M, Coates T, Eshleman SH. Estimation of HIV incidence in a large, community-based, randomized clinical trial: NIMH project accept (HIV Prevention Trials Network 043). PLoS One. 2013; 8(7):e68349. PMID: 23874597; PMCID: PMC3708944.
      44. Romero Z, Urbinati F, Geiger S, Cooper AR, Wherley J, Kaufman ML, Hollis RP, de Assin RR, Senadheera S, Sahagian A, Jin X, Gellis A, Wang X, Gjertson D, Deoliveira S, Kempert P, Shupien S, Abdel-Azim H, Walters MC, Meiselman HJ, Wenby RB, Gruber T, Marder V, Coates T, Kohn DB. ß-globin gene transfer to human bone marrow for sickle cell disease. J Clin Invest. 2013 Jul 01. PMID: 23863630.
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      45. Young SD, Szekeres G, Coates T. The relationship between online social networking and sexual risk behaviors among men who have sex with men (MSM). PLoS One. 2013; 8(5):e62271. PMID: 23658716; PMCID: PMC3642936.
      46. Clark J, Salvatierra J, Segura E, Salazar X, Konda K, Perez-Brumer A, Hall E, Klausner J, Caceres C, Coates T. Moderno love: sexual role-based identities and HIV/STI prevention among men who have sex with men in Lima, Peru. AIDS Behav. 2013 May; 17(4):1313-28. PMID: 22614747; PMCID: PMC3494756.
      47. Jordan L, Swerdlow P, Coates T. Systematic review of transition from adolescent to adult care in patients with sickle cell disease. J Pediatr Hematol Oncol. 2013 Apr; 35(3):165-9. PMID: 23511487.
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      48. Switzer WM, Shankar A, Trimble SR, Thompson AA, Giardina PJ, Cohen AR, Coates T, Vichinsky E, Neufeld EJ, Boudreaux JM, Heneine W. Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients. AIDS Res Hum Retroviruses. 2013 Jul; 29(7):1006-9. PMID: 23409829.
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      49. Meloni A, Detterich J, Berdoukas V, Pepe A, Lombardi M, Coates T, Wood JC. Comparison of biventricular dimensions and function between pediatric sickle-cell disease and thalassemia major patients without cardiac iron. Am J Hematol. 2013 Mar; 88(3):213-8. PMID: 23386313.
        View in: PubMed
      50. Sohn EY, Kato R, Noetzli LJ, Gera A, Coates T, Harmatz P, Keens TG, Wood JC. Exercise performance in thalassemia major: correlation with cardiac iron burden. Am J Hematol. 2013 Mar; 88(3):193-7. PMID: 23339082.
        View in: PubMed
      51. Haines D, Martin M, Carson S, Oliveros O, Green S, Coates T, Eile J, Schilling L, Dinu B, Mendoza T, Gerstenberger E, Trachtenberg F, Vichinsky E. Pain in thalassaemia: the effects of age on pain frequency and severity. Br J Haematol. 2013 Mar; 160(5):680-7. PMID: 23278768.
        View in: PubMed
      52. Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P. Increased leucocyte apoptosis in transfused ß-thalassaemia patients. Br J Haematol. 2013 Feb; 160(3):399-403. PMID: 23216540; PMCID: PMC4597914.
      53. Detterich JA, Sangkatumvong S, Kato R, Dongelyan A, Bush A, Khoo M, Meiselman HJ, Coates T, Wood JC. Patients with sickle cell anemia on simple chronic transfusion protocol show sex differences for hemodynamic and hematologic responses to transfusion. Transfusion. 2013 May; 53(5):1059-68. PMID: 23176402; PMCID: PMC3957479.
      54. Berdoukas V, Farmaki K, Carson S, Wood J, Coates T. Treating thalassemia major-related iron overload: the role of deferiprone. J Blood Med. 2012; 3:119-29. PMID: 23112580; PMCID: PMC3480237.
      55. Connes P, Coates T. Autonomic nervous system dysfunction: implication in sickle cell disease. C R Biol. 2013 Mar; 336(3):142-7. PMID: 23643396.
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      56. Detterich J, Alexy T, Rabai M, Wenby R, Dongelyan A, Coates T, Wood J, Meiselman H. Low-shear red blood cell oxygen transport effectiveness is adversely affected by transfusion and further worsened by deoxygenation in sickle cell disease patients on chronic transfusion therapy. Transfusion. 2013 Feb; 53(2):297-305. PMID: 22882132; PMCID: PMC3510323.
      57. Sullivan PS, Carballo-Diéguez A, Coates T, Goodreau SM, McGowan I, Sanders EJ, Smith A, Goswami P, Sanchez J. Successes and challenges of HIV prevention in men who have sex with men. Lancet. 2012 Jul 28; 380(9839):388-99. PMID: 22819659; PMCID: PMC3670988.
      58. Baveewo S, Kamya MR, Mayanja-Kizza H, Fatch R, Bangsberg DR, Coates T, Hahn JA, Wanyenze RK. Potential for false positive HIV test results with the serial rapid HIV testing algorithm. BMC Res Notes. 2012 Mar 19; 5:154. PMID: 22429706; PMCID: PMC3392728.
      59. Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood. 2012 Mar 22; 119(12):2746-53. PMID: 22279056; PMCID: PMC3327453.
      60. Noetzli LJ, Panigrahy A, Mittelman SD, Hyderi A, Dongelyan A, Coates T, Wood JC. Pituitary iron and volume predict hypogonadism in transfusional iron overload. Am J Hematol. 2012 Feb; 87(2):167-71. PMID: 22213195.
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      61. Noetzli LJ, Mittelman SD, Watanabe RM, Coates T, Wood JC. Pancreatic iron and glucose dysregulation in thalassemia major. Am J Hematol. 2012 Feb; 87(2):155-60. PMID: 22120775.
        View in: PubMed
      62. Detterich J, Noetzli L, Dorey F, Bar-Cohen Y, Harmatz P, Coates T, Wood J. Electrocardiographic consequences of cardiac iron overload in thalassemia major. Am J Hematol. 2012 Feb; 87(2):139-44. PMID: 22052662; PMCID: PMC3306475.
      63. Piwowar-Manning E, Fiamma A, Laeyendecker O, Kulich M, Donnell D, Szekeres G, Robins-Morris L, Mullis CE, Vallari A, Hackett J, Mastro TD, Gray G, Richter L, Alexandre MW, Chariyalertsak S, Chingono A, Sweat M, Coates T, Eshleman SH. HIV surveillance in a large, community-based study: results from the pilot study of Project Accept (HIV Prevention Trials Network 043). BMC Infect Dis. 2011 Sep 24; 11:251. PMID: 21943026; PMCID: PMC3198953.
      64. Sangkatumvong S, Khoo MC, Kato R, Detterich JA, Bush A, Keens TG, Meiselman HJ, Wood JC, Coates T. Peripheral vasoconstriction and abnormal parasympathetic response to sighs and transient hypoxia in sickle cell disease. Am J Respir Crit Care Med. 2011 Aug 15; 184(4):474-81. PMID: 21616995; PMCID: PMC3175540.
      65. Sohn EY, Noetzli LJ, Gera A, Kato R, Coates T, Harmatz P, Keens TG, Wood JC. Pulmonary function in thalassaemia major and its correlation with body iron stores. Br J Haematol. 2011 Oct; 155(1):102-5. PMID: 21810090; PMCID: PMC3169737.
      66. Wanyenze RK, Kamya MR, Fatch R, Mayanja-Kizza H, Baveewo S, Sawires S, Bangsberg DR, Coates T, Hahn JA. Missed opportunities for HIV testing and late-stage diagnosis among HIV-infected patients in Uganda. PLoS One. 2011; 6(7):e21794. PMID: 21750732; PMCID: PMC3130049.
      67. Young SD, Konda K, Caceres C, Galea J, Sung-Jae L, Salazar X, Coates T. Effect of a community popular opinion leader HIV/STI intervention on stigma in urban, coastal Peru. AIDS Behav. 2011 Jul; 15(5):930-7. PMID: 20953691; PMCID: PMC3110996.
      68. Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Br J Haematol. 2011 Aug; 154(3):387-97. PMID: 21592110; PMCID: PMC3170481.
      69. Coates T. Is it time to SWiTCH to composite primary endpoints? Pediatr Blood Cancer. 2011 Dec 01; 57(6):906-7. PMID: 21594983.
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      70. Sweat M, Morin S, Celentano D, Mulawa M, Singh B, Mbwambo J, Kawichai S, Chingono A, Khumalo-Sakutukwa G, Gray G, Richter L, Kulich M, Sadowski A, Coates T. Community-based intervention to increase HIV testing and case detection in people aged 16-32 years in Tanzania, Zimbabwe, and Thailand (NIMH Project Accept, HPTN 043): a randomised study. Lancet Infect Dis. 2011 Jul; 11(7):525-32. PMID: 21546309; PMCID: PMC3156626.
      71. Mindry D, Maman S, Chirowodza A, Muravha T, van Rooyen H, Coates T. Looking to the future: South African men and women negotiating HIV risk and relationship intimacy. Cult Health Sex. 2011 May; 13(5):589-602. PMID: 21452093; PMCID: PMC3071520.
      72. Wanyenze RK, Hahn JA, Liechty CA, Ragland K, Ronald A, Mayanja-Kizza H, Coates T, Kamya MR, Bangsberg DR. Linkage to HIV care and survival following inpatient HIV counseling and testing. AIDS Behav. 2011 May; 15(4):751-60. PMID: 20431933; PMCID: PMC3082586.
      73. Trachtenberg F, Vichinsky E, Haines D, Pakbaz Z, Mednick L, Sobota A, Kwiatkowski J, Thompson AA, Porter J, Coates T, Giardina PJ, Olivieri N, Yamashita R, Neufeld EJ. Iron chelation adherence to deferoxamine and deferasirox in thalassemia. Am J Hematol. 2011 May; 86(5):433-6. PMID: 21523808; PMCID: PMC4599708.
      74. Wood JC, Mo A, Gera A, Koh M, Coates T, Gilsanz V. Quantitative computed tomography assessment of transfusional iron overload. Br J Haematol. 2011 Jun; 153(6):780-5. PMID: 21517807.
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      75. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates T. Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial. Haematologica. 2011 Jul; 96(7):1055-8. PMID: 21393329; PMCID: PMC3128226.
      76. Wolfson JA, Schrager SM, Khanna R, Coates T, Kipke MD. Sickle cell disease in California: sociodemographic predictors of emergency department utilization. Pediatr Blood Cancer. 2012 Jan; 58(1):66-73. PMID: 21360655; PMCID: PMC3272000.
      77. Berdoukas V, Farmaki K, Wood JC, Coates T. Iron chelation in thalassemia: time to reconsider our comfort zones. Expert Rev Hematol. 2011 Feb; 4(1):17-26. PMID: 21322775.
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      78. Coates T. So what if blood is thicker than water? Blood. 2011 Jan 20; 117(3):745-6. PMID: 21252094.
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      79. Noetzli LJ, Carson S, Coates T, Wood JC. Revisiting the relationship between vitamin D deficiency, cardiac iron and cardiac function in thalassemia major. Eur J Haematol. 2011 Feb; 86(2):176-7. PMID: 20942841.
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      80. Young SD, Hlavka Z, Modiba P, Gray G, Van Rooyen H, Richter L, Szekeres G, Coates T. HIV-related stigma, social norms, and HIV testing in Soweto and Vulindlela, South Africa: National Institutes of Mental Health Project Accept (HPTN 043). J Acquir Immune Defic Syndr. 2010 Dec 15; 55(5):620-4. PMID: 20980913; PMCID: PMC3136617.
      81. Noetzli LJ, Coates T, Wood JC. Pancreatic iron loading in chronically transfused sickle cell disease is lower than in thalassaemia major. Br J Haematol. 2011 Jan; 152(2):229-33. PMID: 21118197.
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      82. Wolfson JA, Schrager SM, Coates T, Kipke MD. Sickle-cell disease in California: a population-based description of emergency department utilization. Pediatr Blood Cancer. 2011 Mar; 56(3):413-9. PMID: 21225920; PMCID: PMC3286652.
      83. Parekh C, Hofstra T, Church JA, Coates T. Hemophagocytic lymphohistiocytosis in children with chronic granulomatous disease. Pediatr Blood Cancer. 2011 Mar; 56(3):460-2. PMID: 21225928.
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      84. Donnell D, Mimiaga MJ, Mayer K, Chesney M, Koblin B, Coates T. Use of non-occupational post-exposure prophylaxis does not lead to an increase in high risk sex behaviors in men who have sex with men participating in the EXPLORE trial. AIDS Behav. 2010 Oct; 14(5):1182-9. PMID: 20490908; PMCID: PMC2944957.
      85. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates T. Follow-up report on the 2-year cardiac data from a deferasirox monotherapy trial. Am J Hematol. 2010 Oct; 85(10):818-9. PMID: 20799360.
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      86. Wood JC, Noetzl L, Hyderi A, Joukar M, Coates T, Mittelman S. Predicting pituitary iron and endocrine dysfunction. Ann N Y Acad Sci. 2010 Aug; 1202:123-8. PMID: 20712782.
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      87. Trachtenberg F, Foote D, Martin M, Carson S, Coates T, Beams O, Vega O, Merelles-Pulcini M, Giardina PJ, Kleinert DA, Kwiatkowski J, Thompson AA, Neufeld EJ, Schilling L, Thayalasuthan V, Pakbaz Z, Yamashita R. Pain as an emergent issue in thalassemia. Am J Hematol. 2010 May; 85(5):367-70. PMID: 20232403.
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      88. Wood JC, Kang BP, Thompson A, Giardina P, Harmatz P, Glynos T, Paley C, Coates T. The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Blood. 2010 Jul 29; 116(4):537-43. PMID: 20421452.
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      89. Berdoukas V, Carson S, Nord A, Dongelyan A, Gavin S, Hofstra TC, Wood JC, Coates T. Combining two orally active iron chelators for thalassemia. Ann Hematol. 2010 Nov; 89(11):1177-8. PMID: 20217085.
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      90. Sangkatumvong S, Coates T, Wood JC, Meiselman HJ, Kato R, Detterich JA, Bush A, Khoo MC. Time-varying analysis of autonomic control in response to spontaneous sighs in sickle cell anemia. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:1626-9. PMID: 21096136.
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      91. Singer ST, Kim HY, Olivieri NF, Kwiatkowski JL, Coates T, Carson S, Neufeld E, Cunningham MJ, Giardina PJ, Mueller BU, Quinn CT, Fung E, Vichinsky E. Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications. Am J Hematol. 2009 Nov; 84(11):759-61. PMID: 19787795; PMCID: PMC4254706.
      92. Noetzli LJ, Papudesi J, Coates T, Wood JC. Pancreatic iron loading predicts cardiac iron loading in thalassemia major. Blood. 2009 Nov 05; 114(19):4021-6. PMID: 19726718; PMCID: PMC2774543.
      93. Adamkiewicz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, Coates T, Wang W, Adams RJ. Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury. Blood. 2009 Nov 19; 114(21):4632-8. PMID: 19721013; PMCID: PMC2780299.
      94. Ghugre NR, Gonzalez-Gomez I, Butensky E, Noetzli L, Fischer R, Williams R, Harmatz P, Coates T, Wood JC. Patterns of hepatic iron distribution in patients with chronically transfused thalassemia and sickle cell disease. Am J Hematol. 2009 Aug; 84(8):480-3. PMID: 19536851; PMCID: PMC2884400.
      95. Hudelson SE, Marlowe N, Huang W, Bruce R, Church JD, Husnik M, Donnell D, Coates T, Jackson JB, Chesney M, Koblin B, Eshleman SH. Analysis of HIV type 1 gp41 and enfuvirtide susceptibility among men in the United States who were HIV infected prior to availability of HIV entry inhibitors. AIDS Res Hum Retroviruses. 2009 Jul; 25(7):701-5. PMID: 19552592; PMCID: PMC2746939.
      96. Claster S, Wood JC, Noetzli L, Carson SM, Hofstra TC, Khanna R, Coates T. Nutritional deficiencies in iron overloaded patients with hemoglobinopathies. Am J Hematol. 2009 Jun; 84(6):344-8. PMID: 19415722; PMCID: PMC2887656.
      97. Kauf TL, Coates T, Huazhi L, Mody-Patel N, Hartzema AG. The cost of health care for children and adults with sickle cell disease. Am J Hematol. 2009 Jun; 84(6):323-7. PMID: 19358302.
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      98. Inamo J, Connes P, Barthélémy JC, Dan V, Coates T, Loko G. Pulmonary hypertension does not affect the autonomic nervous system dysfunction of sickle cell disease. Am J Hematol. 2009 May; 84(5):311-2. PMID: 19260125.
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      99. Brewer CJ, Coates T, Wood JC. Spleen R2 and R2* in iron-overloaded patients with sickle cell disease and thalassemia major. J Magn Reson Imaging. 2009 Feb; 29(2):357-64. PMID: 19161188; PMCID: PMC2906451.
      100. Wong LH, Rooyen HV, Modiba P, Richter L, Gray G, McIntyre JA, Schetter CD, Coates T. Test and tell: correlates and consequences of testing and disclosure of HIV status in South Africa (HPTN 043 Project Accept). J Acquir Immune Defic Syndr. 2009 Feb 01; 50(2):215-22. PMID: 19131885; PMCID: PMC2729272.
      101. Chirowodza A, van Rooyen H, Joseph P, Sikotoyi S, Richter L, Coates T. USING PARTICIPATORY METHODS AND GEOGRAPHIC INFORMATION SYSTEMS (GIS) TO PREPARE FOR AN HIV COMMUNITY-BASED TRIAL IN VULINDLELA, SOUTH AFRICA (Project Accept-HPTN 043). J Community Psychol. 2009; 37(1):41-57. PMID: 19774224.
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      102. Schein A, Enriquez C, Coates T, Wood JC. Magnetic resonance detection of kidney iron deposition in sickle cell disease: a marker of chronic hemolysis. J Magn Reson Imaging. 2008 Sep; 28(3):698-704. PMID: 18777554; PMCID: PMC2597353.
      103. Noetzli LJ, Carson SM, Nord AS, Coates T, Wood JC. Longitudinal analysis of heart and liver iron in thalassemia major. Blood. 2008 Oct 01; 112(7):2973-8. PMID: 18650452; PMCID: PMC2556627.
      104. Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P. Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial. Haematologica. 2008 Jun; 93(6):817-25. PMID: 18469351.
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      105. Wood JC, Origa R, Agus A, Matta G, Coates T, Galanello R. Onset of cardiac iron loading in pediatric patients with thalassemia major. Haematologica. 2008 Jun; 93(6):917-20. PMID: 18413890; PMCID: PMC2892933.
      106. Vichinsky E, Pakbaz Z, Onyekwere O, Porter J, Swerdlow P, Coates T, Lane P, Files B, Mueller BU, Coïc L, Forni GL, Fischer R, Marks P, Rofail D, Abetz L, Baladi JF. Patient-reported outcomes of deferasirox (Exjade, ICL670) versus deferoxamine in sickle cell disease patients with transfusional hemosiderosis. Substudy of a randomized open-label phase II trial. Acta Haematol. 2008; 119(3):133-41. PMID: 18408362.
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      107. Delea TE, Hagiwara M, Thomas SK, Baladi JF, Phatak PD, Coates T. Outcomes, utilization, and costs among thalassemia and sickle cell disease patients receiving deferoxamine therapy in the United States. Am J Hematol. 2008 Apr; 83(4):263-70. PMID: 17924547.
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      108. Wood JC, Claster S, Carson S, Menteer JD, Hofstra T, Khanna R, Coates T. Vitamin D deficiency, cardiac iron and cardiac function in thalassaemia major. Br J Haematol. 2008 Jun; 141(6):891-4. PMID: 18371108; PMCID: PMC2892922.
      109. Fung EB, Harmatz PR, Milet M, Coates T, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP. Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia. Bone. 2008 Jul; 43(1):162-8. PMID: 18430624; PMCID: PMC2500183.
      110. Li W, Coates T, Wood JC. Atrial dysfunction as a marker of iron cardiotoxicity in thalassemia major. Haematologica. 2008 Feb; 93(2):311-2. PMID: 18245658; PMCID: PMC2887655.
      111. Sangkatumvong S, Khoo MC, Coates T. Abnormal cardiac autonomic control in sickle cell disease following transient hypoxia. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1996-9. PMID: 19163084.
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      112. Jacob E, Hockenberry M, Mueller BU, Coates T, Zeltzer L. Analgesic Response to Morphine in Children with Sickle Cell Disease: A Pilot Study. J Pain Manag. 2008; 2(1):179-190. PMID: 20104257.
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      113. Delea TE, Edelsberg J, Sofrygin O, Thomas SK, Baladi JF, Phatak PD, Coates T. Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review. Transfusion. 2007 Oct; 47(10):1919-29. PMID: 17880620.
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      114. Eshleman SH, Husnik M, Hudelson S, Donnell D, Huang Y, Huang W, Hart S, Jackson B, Coates T, Chesney M, Koblin B. Antiretroviral drug resistance, HIV-1 tropism, and HIV-1 subtype among men who have sex with men with recent HIV-1 infection. AIDS. 2007 May 31; 21(9):1165-74. PMID: 17502727.
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      115. Cappellini MD, Bejaoui M, Agaoglu L, Porter J, Coates T, Jeng M, Lai ME, Mangiagli A, Strauss G, Girot R, Watman N, Ferster A, Loggetto S, Abish S, Cario H, Zoumbos N, Vichinsky E, Opitz H, Ressayre-Djaffer C, Abetz L, Rofail D, Baladi JF. Prospective evaluation of patient-reported outcomes during treatment with deferasirox or deferoxamine for iron overload in patients with beta-thalassemia. Clin Ther. 2007 May; 29(5):909-17. PMID: 17697909.
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      116. Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T. A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Br J Haematol. 2007 Feb; 136(3):501-8. PMID: 17233848; PMCID: PMC1974786.
      117. Delea TE, Sofrygin O, Thomas SK, Baladi JF, Phatak PD, Coates T. Cost effectiveness of once-daily oral chelation therapy with deferasirox versus infusional deferoxamine in transfusion-dependent thalassaemia patients: US healthcare system perspective. Pharmacoeconomics. 2007; 25(4):329-42. PMID: 17402805.
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      118. Maiorana A, Kegeles S, Fernandez P, Salazar X, Cáceres C, Sandoval C, Rosasco AM, Coates T. Implementation and evaluation of an HIV/STD intervention in Peru. Eval Program Plann. 2007 Feb; 30(1):82-93. PMID: 17689315; PMCID: PMC2739095.
      119. Morris SR, Klausner JD, Buchbinder SP, Wheeler SL, Koblin B, Coates T, Chesney M, Colfax GN. Prevalence and incidence of pharyngeal gonorrhea in a longitudinal sample of men who have sex with men: the EXPLORE study. Clin Infect Dis. 2006 Nov 15; 43(10):1284-9. PMID: 17051493.
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      120. Sayles JN, Pettifor A, Wong MD, MacPhail C, Lee SJ, Hendriksen E, Rees HV, Coates T. Factors associated with self-efficacy for condom use and sexual negotiation among South african youth. J Acquir Immune Defic Syndr. 2006 Oct 01; 43(2):226-33. PMID: 16951647; PMCID: PMC2819666.
      121. Ghugre NR, Enriquez CM, Gonzalez I, Nelson MD, Coates T, Wood JC. MRI detects myocardial iron in the human heart. Magn Reson Med. 2006 Sep; 56(3):681-6. PMID: 16888797; PMCID: PMC2887674.
      122. McNamara G, Gupta A, Reynaert J, Coates T, Boswell C. Spectral imaging microscopy web sites and data. Cytometry A. 2006 Aug 01; 69(8):863-71. PMID: 16969821.
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      123. Ghugre NR, Enriquez CM, Coates T, Nelson MD, Wood JC. Improved R2* measurements in myocardial iron overload. J Magn Reson Imaging. 2006 Jan; 23(1):9-16. PMID: 16329085; PMCID: PMC2892961.
      124. Ballas SK, Files B, Luchtman-Jones L, Benjamin L, Swerdlow P, Hilliard L, Coates T, Abboud M, Wojtowicz-Praga S, Kuypers FA, Michael Grindel J. Secretory phospholipase A2 levels in patients with sickle cell disease and acute chest syndrome. Hemoglobin. 2006; 30(2):165-70. PMID: 16798640.
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      125. Cappellini MD, Cohen A, Piga A, Bejaoui M, Perrotta S, Agaoglu L, Aydinok Y, Kattamis A, Kilinc Y, Porter J, Capra M, Galanello R, Fattoum S, Drelichman G, Magnano C, Verissimo M, Athanassiou-Metaxa M, Giardina P, Kourakli-Symeonidis A, Janka-Schaub G, Coates T, Vermylen C, Olivieri N, Thuret I, Opitz H, Ressayre-Djaffer C, Marks P, Alberti D. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood. 2006 May 01; 107(9):3455-62. PMID: 16352812.
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      126. Wu S, Gonzalez-Gomez I, Coates T, Yano S. Cobalamin C disease presenting with hemophagocytic lymphohistiocytosis. Pediatr Hematol Oncol. 2005 Dec; 22(8):717-21. PMID: 16251179.
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      127. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates T, Davies S, Sweeters N, Vichinsky EP. Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome. Br J Haematol. 2005 Nov; 131(3):378-88. PMID: 16225658.
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      128. Ghugre NR, Coates T, Nelson MD, Wood JC. Mechanisms of tissue-iron relaxivity: nuclear magnetic resonance studies of human liver biopsy specimens. Magn Reson Med. 2005 Nov; 54(5):1185-93. PMID: 16215963; PMCID: PMC2892963.
      129. Wood JC, Otto-Duessel M, Aguilar M, Nick H, Nelson MD, Coates T, Pollack H, Moats R. Cardiac iron determines cardiac T2*, T2, and T1 in the gerbil model of iron cardiomyopathy. Circulation. 2005 Jul 26; 112(4):535-43. PMID: 16027257; PMCID: PMC2896311.
      130. Wood JC, Enriquez C, Ghugre N, Tyzka JM, Carson S, Nelson MD, Coates T. MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood. 2005 Aug 15; 106(4):1460-5. PMID: 15860670; PMCID: PMC1895207.
      131. Wood JC, Enriquez C, Ghugre N, Otto-Duessel M, Aguilar M, Nelson MD, Moats R, Coates T. Physiology and pathophysiology of iron cardiomyopathy in thalassemia. Ann N Y Acad Sci. 2005; 1054:386-95. PMID: 16339687; PMCID: PMC2892916.
      132. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates T, Davies S, Sweeters N, Vichinsky EP. Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. Ann N Y Acad Sci. 2005; 1054:250-6. PMID: 16339672.
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      133. Ballas SK, Files B, Luchtman-Jones L, Benjamin L, Swerdlow P, Hilliard L, Coates T, Abboud M, Wojtowicz-Praga S, Grindel JM. Safety of purified poloxamer 188 in sickle cell disease: phase I study of a non-ionic surfactant in the management of acute chest syndrome. Hemoglobin. 2004 May; 28(2):85-102. PMID: 15182051.
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      134. Wood JC, Tyszka JM, Carson S, Nelson MD, Coates T. Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease. Blood. 2004 Mar 01; 103(5):1934-6. PMID: 14630822.
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      135. Perelman N, Selvaraj SK, Batra S, Luck LR, Erdreich-Epstein A, Coates T, Kalra VK, Malik P. Placenta growth factor activates monocytes and correlates with sickle cell disease severity. Blood. 2003 Aug 15; 102(4):1506-14. PMID: 12714517.
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      136. Coates T, Larson-Prior LJ, Wolpert S, Prior F. Classification of simple stimuli based on detected nerve activity. IEEE Eng Med Biol Mag. 2003 Jan-Feb; 22(1):64-76. PMID: 12683065.
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      137. Kyono W, Coates T. A practical approach to neutrophil disorders. Pediatr Clin North Am. 2002 Oct; 49(5):929-71, viii. PMID: 12430620.
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      138. Sheikh J, Goldberg BJ, Kaplan MS, Staveren AM, Coates T. A case of neutropenia with transient absence of neutrophil chemotaxis. Ann Allergy Asthma Immunol. 2002 May; 88(5):445-50. PMID: 12027063.
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