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Thomas D Coates, MD

Title(s)Professor of Pediatrics
AddressCHL Mail Stop 54
Off Campus
Los Angeles CA 90089
Phone+1 323 361 2352
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    Other Positions
    Title(s)Section Head of Hematology

    Title(s)Director of Sickle/Hemoglobinopathy Program


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    I primarily work in two areas of basic and translational research: 1) the role of inflammation in the genesis of vascular disease in sickle cell disease; 2) the detection and management of transfusion related iron overload. Our research employs various engineering-intensive methodologies (MRI, laser Doppler flow, digital image analysis, signal processing) to explore the basic mechanisms of sickle cell disease and to measure the effect of various treatment modalities. We use direct measures of microvascular blood flow to monitor the process of vasoocclusion and relate it to simultaneous measures of autonomic nervous system function. These methodologies translate in measurements that can be used to follow patients clinically. In collaboration with members of the Cardiology, Pulmonology, and Radiology Departments at Children’s Hospital Los Angeles, the Departments of Biomedical Engineering and Physiology/Biophysics at the Keck School of Medicine, we devised methods to measure the sickling process in human sickle cell subjects and relate these measurements to clinical factors that modulate disease severity.

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    Multimodal biophysical markers of vascular disease in hemoglobinopathies
    NIH/NHLBI U01HL117718Aug 15, 2013 - May 31, 2018
    Role: Principal Investigator
    SOUTHERN CALIFORNIA BLOOD SAFETY SURVEILLANCE PROGRAM IN HEMATOLOGICAL DISORFERS
    CDC/NCBDD U50DD000874May 1, 2012 - Apr 30, 2014
    Role: Principal Investigator
    Basic and Translational Research Program
    NIH/NHLBI U54HL090511Jun 15, 2008 - Mar 31, 2012
    Role: Principal Investigator
    Research Initiatives for the Preventions of Complications of Thalassemia
    CDC/NCBDD U01DD000309Sep 30, 2007 - Sep 29, 2012
    Role: Principal Investigator
    Human models of sickle cell vascular damage
    NIH/NHLBI R01HL071801Jul 8, 2003 - Jun 30, 2008
    Role: Principal Investigator
    GRANULES AND ORGANELLES AND LEUKOCYTE ACTIVATION
    NIH/NIAID R01AI023547Sep 1, 1985 - Nov 30, 1999
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Progressive Vasoconstriction with Sequential Thermal Stimulation Indicates Vascular Dysautonomia in Sickle Cell Disease. Blood. 2020 Jun 09. Veluswamy S, Shah P, Khaleel M, Thuptimdang W, Chalacheva P, Sunwoo J, Denton CC, Kato RM, Detterich JA, Wood JC, Sposto R, Khoo MC, Zeltzer L, Coates TD. PMID: 32518948.
      View in: PubMed   Mentions:    Fields:    
    2. A Phase 3 Trial of Luspatercept in Patients with Transfusion-Dependent ß-Thalassemia. N Engl J Med. 2020 03 26; 382(13):1219-1231. Cappellini MD, Viprakasit V, Taher AT, Georgiev P, Kuo KHM, Coates T, Voskaridou E, Liew HK, Pazgal-Kobrowski I, Forni GL, Perrotta S, Khelif A, Lal A, Kattamis A, Vlachaki E, Origa R, Aydinok Y, Bejaoui M, Ho PJ, Chew LP, Bee PC, Lim SM, Lu MY, Tantiworawit A, Ganeva P, Gercheva L, Shah F, Neufeld EJ, Thompson A, Laadem A, Shetty JK, Zou J, Zhang J, Miteva D, Zinger T, Linde PG, Sherman ML, Hermine O, Porter J, Piga A. PMID: 32212518.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    3. Autonomically-mediated decrease in microvascular blood flow due to mental stress and pain in sickle cell disease: A target for neuromodulatory interventions. Complement Ther Med. 2020 Mar; 49:102334. Martin SR, Shah P, Denton C, Zeltzer LK, Veluswamy S, Khoo MCK, Coates TD. PMID: 32147052.
      View in: PubMed   Mentions:    Fields:    
    4. Aura and mental stress are associated with reports of pain in sickle cell disease-a pilot study using a mobile application. Am J Hematol. 2020 Jan 19. Espinoza J, Shah P, Veluswamy S, Zeltzer L, Khoo MCK, Coates TD, Baskin J. PMID: 31957078.
      View in: PubMed   Mentions:    Fields:    
    5. Iron overload in transfusion-dependent patients. Hematology Am Soc Hematol Educ Program. 2019 12 06; 2019(1):337-344. Coates TD. PMID: 31808901.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. PrEP implementation in pregnant and post-partum women. Lancet HIV. 2020 Jan; 7(1):e5-e6. Joseph Davey D, Myer L, Coates T. PMID: 31813838.
      View in: PubMed   Mentions:    Fields:    
    7. Vaso-Occlusion in Sickle Cell Disease: Is Autonomic Dysregulation of the Microvasculature the Trigger? J Clin Med. 2019 Oct 15; 8(10). Veluswamy S, Shah P, Denton CC, Chalacheva P, Khoo MCK, Coates TD. PMID: 31618931.
      View in: PubMed   Mentions:
    8. Anemia predicts lower white matter volume and cognitive performance in sickle and non-sickle cell anemia syndrome. Am J Hematol. 2019 10; 94(10):1055-1065. Choi S, O'Neil SH, Joshi AA, Li J, Bush AM, Coates TD, Leahy RM, Wood JC. PMID: 31259431.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    9. Erythrocyte and plasma oxidative stress appears to be compensated in patients with sickle cell disease during a period of relative health, despite the presence of known oxidative agents. Free Radic Biol Med. 2019 09; 141:408-415. Detterich JA, Liu H, Suriany S, Kato RM, Chalacheva P, Tedla B, Shah PM, Khoo MC, Wood JC, Coates TD, Milne GL, Oh JY, Patel RP, Forman HJ. PMID: 31279092.
      View in: PubMed   Mentions:    Fields:    
    10. Sickle cell microvascular paradox-oxygen supply-demand mismatch. Am J Hematol. 2019 06; 94(6):678-688. Detterich JA, Kato R, Bush A, Chalacheva P, Ponce D, De Zoysa M, Shah P, Khoo MC, Meiselman HJ, Coates TD, Wood JC. PMID: 30916797.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    11. Mental stress causes vasoconstriction in subjects with sickle cell disease and in normal controls. Haematologica. 2020 Jan; 105(1):83-90. Shah P, Khaleel M, Thuptimdang W, Sunwoo J, Veluswamy S, Chalacheva P, Kato RM, Detterich J, Wood JC, Zeltzer L, Sposto R, Khoo MCK, Coates TD. PMID: 30975906.
      View in: PubMed   Mentions: 1     Fields:    
    12. Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt. Front Physiol. 2019; 10:381. Chalacheva P, Kato RM, Shah P, Veluswamy S, Denton CC, Sunwoo J, Thuptimdang W, Wood JC, Detterich JA, Coates TD, Khoo MCK. PMID: 31031633.
      View in: PubMed   Mentions:
    13. White matter has impaired resting oxygen delivery in sickle cell patients. Am J Hematol. 2019 04; 94(4):467-474. Chai Y, Bush AM, Coloigner J, Nederveen AJ, Tamrazi B, Vu C, Choi S, Coates TD, Lepore N, Wood JC. PMID: 30697803.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    14. A novel cross-correlation methodology for assessing biophysical responses associated with pain. J Pain Res. 2018; 11:2207-2219. Sunwoo J, Chalacheva P, Khaleel M, Shah P, Sposto R, Kato RM, Detterich J, Zeltzer LK, Wood JC, Coates TD, Khoo MC. PMID: 30323655.
      View in: PubMed   Mentions:
    15. Effectiveness of Clinical Decision Support Based Intervention in the Improvement of Care for Adult Sickle Cell Disease Patients in Primary Care. J Am Board Fam Med. 2018 Sep-Oct; 31(5):812-816. Mainous AG, Carek PJ, Lynch K, Tanner RJ, Hulihan MM, Baskin J, Coates TD. PMID: 30201679.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. You don't always get what you want: Does hypoxia cause sickle cell crisis? Am J Hematol. 2018 08; 93(4):475-477. Coates TD. PMID: 29377212.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Autonomic nervous system involvement in sickle cell disease. Clin Hemorheol Microcirc. 2018; 68(2-3):251-262. Coates TD, Chalacheva P, Zeltzer L, Khoo MCK. PMID: 29614636.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Pseudo continuous arterial spin labeling quantification in anemic subjects with hyperemic cerebral blood flow. Magn Reson Imaging. 2018 04; 47:137-146. Bush A, Chai Y, Choi SY, Vaclavu L, Holland S, Nederveen A, Coates T, Wood J. PMID: 29229306.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    19. Contrasting resting-state fMRI abnormalities from sickle and non-sickle anemia. PLoS One. 2017; 12(10):e0184860. Coloigner J, Kim Y, Bush A, Choi S, Balderrama MC, Coates TD, O'Neil SH, Lepore N, Wood JC. PMID: 28981541.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Graph Lasso-Based Test for Evaluating Functional Brain Connectivity in Sickle Cell Disease. Brain Connect. 2017 09; 7(7):443-453. Coloigner J, Phlypo R, Coates TD, Lepore N, Wood JC. PMID: 28747064.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Individuals with sickle cell disease have a significantly greater vasoconstriction response to thermal pain than controls and have significant vasoconstriction in response to anticipation of pain. Am J Hematol. 2017 Nov; 92(11):1137-1145. Khaleel M, Puliyel M, Shah P, Sunwoo J, Kato RM, Chalacheva P, Thuptimdang W, Detterich J, Wood JC, Tsao J, Zeltzer L, Sposto R, Khoo MCK, Coates TD. PMID: 28707371.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    22. The effect of hypnosis on pain and peripheral blood flow in sickle-cell disease: a pilot study. J Pain Res. 2017; 10:1635-1644. Bhatt RR, Martin SR, Evans S, Lung K, Coates TD, Zeltzer LK, Tsao JC. PMID: 28769584.
      View in: PubMed   Mentions:
    23. Ultra-short echo time images quantify high liver iron. Magn Reson Med. 2018 03; 79(3):1579-1585. Doyle EK, Toy K, Valdez B, Chia JM, Coates T, Wood JC. PMID: 28643355.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    24. Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease. PLoS One. 2017; 12(5):e0178353. Chalacheva P, Khaleel M, Sunwoo J, Shah P, Detterich JA, Kato RM, Thuptimdang W, Meiselman HJ, Sposto R, Tsao J, Wood JC, Zeltzer L, Coates TD, Khoo MCK. PMID: 28542469.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    25. Hemoglobin and mean platelet volume predicts diffuse T1-MRI white matter volume decrease in sickle cell disease patients. Neuroimage Clin. 2017; 15:239-246. Choi S, Bush AM, Borzage MT, Joshi AA, Mack WJ, Coates TD, Leahy RM, Wood JC. PMID: 28540180.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    26. How we manage iron overload in sickle cell patients. Br J Haematol. 2017 06; 177(5):703-716. Coates TD, Wood JC. PMID: 28295188.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    27. Emergency department utilization by Californians with sickle cell disease, 2005-2014. Pediatr Blood Cancer. 2017 06; 64(6). Paulukonis ST, Feuchtbaum LB, Coates TD, Neumayr LD, Treadwell MJ, Vichinsky EP, Hulihan MM. PMID: 28000344.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    28. Unchanneling cardiac iron in humans. Blood. 2016 09 22; 128(12):1538-40. Coates TD. PMID: 27658696.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Empirical model of human blood transverse relaxation at 3?T improves MRI T2 oximetry. Magn Reson Med. 2017 06; 77(6):2364-2371. Bush A, Borzage M, Detterich J, Kato RM, Meiselman HJ, Coates T, Wood JC. PMID: 27385283.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. From Mosquitos to Humans: Genetic Evolution of Zika Virus. Cell Host Microbe. 2016 May 11; 19(5):561-5. Wang L, Valderramos SG, Wu A, Ouyang S, Li C, Brasil P, Bonaldo M, Coates T, Nielsen-Saines K, Jiang T, Aliyari R, Cheng G. PMID: 27091703.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    31. Management of iron overload in hemoglobinopathies: what is the appropriate target iron level? Ann N Y Acad Sci. 2016 03; 1368(1):95-106. Coates TD, Carson S, Wood JC, Berdoukas V. PMID: 27186942.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    32. Predictors of cerebral blood flow in patients with and without anemia. J Appl Physiol (1985). 2016 Apr 15; 120(8):976-81. Borzage MT, Bush AM, Choi S, Nederveen AJ, Václavu L, Coates TD, Wood JC. PMID: 26796758.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    33. Early Cardiac Iron Overload in a Child on Treatment of Acute Lymphoblastic Leukemia. Pediatrics. 2015 Sep; 136(3):e697-700. Reitman AJ, Coates TD, Freyer DR. PMID: 26283784.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Iron and oxidative stress in cardiomyopathy in thalassemia. Free Radic Biol Med. 2015 Nov; 88(Pt A):3-9. Berdoukas V, Coates TD, Cabantchik ZI. PMID: 26216855.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    35. Autonomic responses to cold face stimulation in sickle cell disease: a time-varying model analysis. Physiol Rep. 2015 Jul 14; 3(7). Chalacheva P, Kato RM, Sangkatumvong S, Detterich J, Bush A, Wood JC, Meiselman H, Coates TD, Khoo MC. PMID: 26177958.
      View in: PubMed   Mentions: 3     Fields:    
    36. Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease. Blood. 2015 Aug 06; 126(6):703-10. Detterich JA, Kato RM, Rabai M, Meiselman HJ, Coates TD, Wood JC. PMID: 26036801.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    37. A significant proportion of thalassemia major patients have adrenal insufficiency detectable on provocative testing. J Pediatr Hematol Oncol. 2015 Jan; 37(1):54-9. Huang KE, Mittelman SD, Coates TD, Geffner ME, Wood JC. PMID: 24942024.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    38. Iron toxicity and its possible association with treatment of Cancer: lessons from hemoglobinopathies and rare, transfusion-dependent anemias. Free Radic Biol Med. 2015 Feb; 79:343-51. Puliyel M, Mainous AG, Berdoukas V, Coates TD. PMID: 25463277.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    39. Population based surveillance in sickle cell disease: methods, findings and implications from the California registry and surveillance system in hemoglobinopathies project (RuSH). Pediatr Blood Cancer. 2014 Dec; 61(12):2271-6. Paulukonis ST, Harris WT, Coates TD, Neumayr L, Treadwell M, Vichinsky E, Feuchtbaum LB. PMID: 25176145.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    40. The impact of chelation therapy on survival in transfusional iron overload: a meta-analysis of myelodysplastic syndrome. Br J Haematol. 2014 Dec; 167(5):720-3. Mainous AG, Tanner RJ, Hulihan MM, Amaya M, Coates TD. PMID: 25048454.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    41. Project HOPE: online social network changes in an HIV prevention randomized controlled trial for African American and Latino men who have sex with men. Am J Public Health. 2014 Sep; 104(9):1707-12. Young SD, Holloway I, Jaganath D, Rice E, Westmoreland D, Coates T. PMID: 25033137.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    42. Cardiac iron overload in sickle-cell disease. Am J Hematol. 2014 Jul; 89(7):678-83. Meloni A, Puliyel M, Pepe A, Berdoukas V, Coates TD, Wood JC. PMID: 24664847.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    43. Physiology and pathophysiology of iron in hemoglobin-associated diseases. Free Radic Biol Med. 2014 Jul; 72:23-40. Coates TD. PMID: 24726864.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    44. Bad liver and a broken heart. Blood. 2014 Mar 06; 123(10):1434-6. Coates TD. PMID: 24627546.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Ferritin trends do not predict changes in total body iron in patients with transfusional iron overload. Am J Hematol. 2014 Apr; 89(4):391-4. Puliyel M, Sposto R, Berdoukas VA, Hofstra TC, Nord A, Carson S, Wood J, Coates TD. PMID: 24347294.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    46. Tissue iron evaluation in chronically transfused children shows significant levels of iron loading at a very young age. Am J Hematol. 2013 Nov; 88(11):E283-5. Berdoukas V, Nord A, Carson S, Puliyel M, Hofstra T, Wood J, Coates TD. PMID: 23861216.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    47. Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME). Transfusion. 2014 Apr; 54(4):972-81; quiz 971. Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA. PMID: 23889533.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansPHPublic Health
    48. Moderno love: sexual role-based identities and HIV/STI prevention among men who have sex with men in Lima, Peru. AIDS Behav. 2013 May; 17(4):1313-28. Clark J, Salvatierra J, Segura E, Salazar X, Konda K, Perez-Brumer A, Hall E, Klausner J, Caceres C, Coates T. PMID: 22614747.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    49. Comparison of biventricular dimensions and function between pediatric sickle-cell disease and thalassemia major patients without cardiac iron. Am J Hematol. 2013 Mar; 88(3):213-8. Meloni A, Detterich J, Berdoukas V, Pepe A, Lombardi M, Coates TD, Wood JC. PMID: 23386313.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    50. Exercise performance in thalassemia major: correlation with cardiac iron burden. Am J Hematol. 2013 Mar; 88(3):193-7. Sohn EY, Kato R, Noetzli LJ, Gera A, Coates T, Harmatz P, Keens TG, Wood JC. PMID: 23339082.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    51. Pain in thalassaemia: the effects of age on pain frequency and severity. Br J Haematol. 2013 Mar; 160(5):680-7. Haines D, Martin M, Carson S, Oliveros O, Green S, Coates T, Eile J, Schilling L, Dinu B, Mendoza T, Gerstenberger E, Trachtenberg F, Vichinsky E. PMID: 23278768.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    52. Patients with sickle cell anemia on simple chronic transfusion protocol show sex differences for hemodynamic and hematologic responses to transfusion. Transfusion. 2013 May; 53(5):1059-68. Detterich JA, Sangkatumvong S, Kato R, Dongelyan A, Bush A, Khoo M, Meiselman HJ, Coates TD, Wood JC. PMID: 23176402.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    53. Low-shear red blood cell oxygen transport effectiveness is adversely affected by transfusion and further worsened by deoxygenation in sickle cell disease patients on chronic transfusion therapy. Transfusion. 2013 Feb; 53(2):297-305. Detterich J, Alexy T, Rabai M, Wenby R, Dongelyan A, Coates T, Wood J, Meiselman H. PMID: 22882132.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsCTClinical Trials
    54. Pituitary iron and volume predict hypogonadism in transfusional iron overload. Am J Hematol. 2012 Feb; 87(2):167-71. Noetzli LJ, Panigrahy A, Mittelman SD, Hyderi A, Dongelyan A, Coates TD, Wood JC. PMID: 22213195.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    55. Pancreatic iron and glucose dysregulation in thalassemia major. Am J Hematol. 2012 Feb; 87(2):155-60. Noetzli LJ, Mittelman SD, Watanabe RM, Coates TD, Wood JC. PMID: 22120775.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    56. Electrocardiographic consequences of cardiac iron overload in thalassemia major. Am J Hematol. 2012 Feb; 87(2):139-44. Detterich J, Noetzli L, Dorey F, Bar-Cohen Y, Harmatz P, Coates T, Wood J. PMID: 22052662.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    57. Peripheral vasoconstriction and abnormal parasympathetic response to sighs and transient hypoxia in sickle cell disease. Am J Respir Crit Care Med. 2011 Aug 15; 184(4):474-81. Sangkatumvong S, Khoo MC, Kato R, Detterich JA, Bush A, Keens TG, Meiselman HJ, Wood JC, Coates TD. PMID: 21616995.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    58. Pulmonary function in thalassaemia major and its correlation with body iron stores. Br J Haematol. 2011 Oct; 155(1):102-5. Sohn EY, Noetzli LJ, Gera A, Kato R, Coates TD, Harmatz P, Keens TG, Wood JC. PMID: 21810090.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    59. Effect of a community popular opinion leader HIV/STI intervention on stigma in urban, coastal Peru. AIDS Behav. 2011 Jul; 15(5):930-7. Young SD, Konda K, Caceres C, Galea J, Sung-Jae L, Salazar X, Coates T. PMID: 20953691.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    60. Is it time to SWiTCH to composite primary endpoints? Pediatr Blood Cancer. 2011 Dec 01; 57(6):906-7. Coates TD. PMID: 21594983.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    61. Quantitative computed tomography assessment of transfusional iron overload. Br J Haematol. 2011 Jun; 153(6):780-5. Wood JC, Mo A, Gera A, Koh M, Coates T, Gilsanz V. PMID: 21517807.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    62. Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial. Haematologica. 2011 Jul; 96(7):1055-8. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. PMID: 21393329.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
    63. Sickle cell disease in California: sociodemographic predictors of emergency department utilization. Pediatr Blood Cancer. 2012 Jan; 58(1):66-73. Wolfson JA, Schrager SM, Khanna R, Coates TD, Kipke MD. PMID: 21360655.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    64. So what if blood is thicker than water? Blood. 2011 Jan 20; 117(3):745-6. Coates TD. PMID: 21252094.
      View in: PubMed   Mentions: 3     Fields:    
    65. Pancreatic iron loading in chronically transfused sickle cell disease is lower than in thalassaemia major. Br J Haematol. 2011 Jan; 152(2):229-33. Noetzli LJ, Coates TD, Wood JC. PMID: 21118197.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    66. Sickle-cell disease in California: a population-based description of emergency department utilization. Pediatr Blood Cancer. 2011 Mar; 56(3):413-9. Wolfson JA, Schrager SM, Coates TD, Kipke MD. PMID: 21225920.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    67. Hemophagocytic lymphohistiocytosis in children with chronic granulomatous disease. Pediatr Blood Cancer. 2011 Mar; 56(3):460-2. Parekh C, Hofstra T, Church JA, Coates TD. PMID: 21225928.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    68. Follow-up report on the 2-year cardiac data from a deferasirox monotherapy trial. Am J Hematol. 2010 Oct; 85(10):818-9. Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. PMID: 20799360.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCTClinical Trials
    69. Predicting pituitary iron and endocrine dysfunction. Ann N Y Acad Sci. 2010 Aug; 1202:123-8. Wood JC, Noetzl L, Hyderi A, Joukar M, Coates T, Mittelman S. PMID: 20712782.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    70. The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores. Blood. 2010 Jul 29; 116(4):537-43. Wood JC, Kang BP, Thompson A, Giardina P, Harmatz P, Glynos T, Paley C, Coates TD. PMID: 20421452.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCTClinical Trials
    71. Time-varying analysis of autonomic control in response to spontaneous sighs in sickle cell anemia. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:1626-9. Sangkatumvong S, Coates TD, Wood JC, Meiselman HJ, Kato R, Detterich JA, Bush A, Khoo MC. PMID: 21096136.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    72. Pancreatic iron loading predicts cardiac iron loading in thalassemia major. Blood. 2009 Nov 05; 114(19):4021-6. Noetzli LJ, Papudesi J, Coates TD, Wood JC. PMID: 19726718.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    73. Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury. Blood. 2009 Nov 19; 114(21):4632-8. Adamkiewicz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, Coates T, Wang W, Adams RJ. PMID: 19721013.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    74. Patterns of hepatic iron distribution in patients with chronically transfused thalassemia and sickle cell disease. Am J Hematol. 2009 Aug; 84(8):480-3. Ghugre NR, Gonzalez-Gomez I, Butensky E, Noetzli L, Fischer R, Williams R, Harmatz P, Coates TD, Wood JC. PMID: 19536851.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    75. Nutritional deficiencies in iron overloaded patients with hemoglobinopathies. Am J Hematol. 2009 Jun; 84(6):344-8. Claster S, Wood JC, Noetzli L, Carson SM, Hofstra TC, Khanna R, Coates TD. PMID: 19415722.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    76. Spleen R2 and R2* in iron-overloaded patients with sickle cell disease and thalassemia major. J Magn Reson Imaging. 2009 Feb; 29(2):357-64. Brewer CJ, Coates TD, Wood JC. PMID: 19161188.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    77. Magnetic resonance detection of kidney iron deposition in sickle cell disease: a marker of chronic hemolysis. J Magn Reson Imaging. 2008 Sep; 28(3):698-704. Schein A, Enriquez C, Coates TD, Wood JC. PMID: 18777554.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    78. Longitudinal analysis of heart and liver iron in thalassemia major. Blood. 2008 Oct 01; 112(7):2973-8. Noetzli LJ, Carson SM, Nord AS, Coates TD, Wood JC. PMID: 18650452.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    79. Onset of cardiac iron loading in pediatric patients with thalassemia major. Haematologica. 2008 Jun; 93(6):917-20. Wood JC, Origa R, Agus A, Matta G, Coates TD, Galanello R. PMID: 18413890.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    80. Outcomes, utilization, and costs among thalassemia and sickle cell disease patients receiving deferoxamine therapy in the United States. Am J Hematol. 2008 Apr; 83(4):263-70. Delea TE, Hagiwara M, Thomas SK, Baladi JF, Phatak PD, Coates TD. PMID: 17924547.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    81. Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia. Bone. 2008 Jul; 43(1):162-168. Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP. PMID: 18430624.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    82. Abnormal cardiac autonomic control in sickle cell disease following transient hypoxia. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1996-9. Sangkatumvong S, Khoo MC, Coates TD. PMID: 19163084.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    83. Consequences and costs of noncompliance with iron chelation therapy in patients with transfusion-dependent thalassemia: a literature review. Transfusion. 2007 Oct; 47(10):1919-29. Delea TE, Edelsberg J, Sofrygin O, Thomas SK, Baladi JF, Phatak PD, Coates TD. PMID: 17880620.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    84. A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Br J Haematol. 2007 Feb; 136(3):501-8. Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T. PMID: 17233848.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCTClinical Trials
    85. Cost effectiveness of once-daily oral chelation therapy with deferasirox versus infusional deferoxamine in transfusion-dependent thalassaemia patients: US healthcare system perspective. Pharmacoeconomics. 2007; 25(4):329-42. Delea TE, Sofrygin O, Thomas SK, Baladi JF, Phatak PD, Coates TD. PMID: 17402805.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    86. Factors associated with self-efficacy for condom use and sexual negotiation among South african youth. J Acquir Immune Defic Syndr. 2006 Oct 01; 43(2):226-33. Sayles JN, Pettifor A, Wong MD, MacPhail C, Lee SJ, Hendriksen E, Rees HV, Coates T. PMID: 16951647.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    87. MRI detects myocardial iron in the human heart. Magn Reson Med. 2006 Sep; 56(3):681-6. Ghugre NR, Enriquez CM, Gonzalez I, Nelson MD, Coates TD, Wood JC. PMID: 16888797.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    88. Improved R2* measurements in myocardial iron overload. J Magn Reson Imaging. 2006 Jan; 23(1):9-16. Ghugre NR, Enriquez CM, Coates TD, Nelson MD, Wood JC. PMID: 16329085.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    89. Cobalamin C disease presenting with hemophagocytic lymphohistiocytosis. Pediatr Hematol Oncol. 2005 Dec; 22(8):717-21. Wu S, Gonzalez-Gomez I, Coates T, Yano S. PMID: 16251179.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    90. Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome. Br J Haematol. 2005 Nov; 131(3):378-88. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP. PMID: 16225658.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCTClinical Trials
    91. Mechanisms of tissue-iron relaxivity: nuclear magnetic resonance studies of human liver biopsy specimens. Magn Reson Med. 2005 Nov; 54(5):1185-93. Ghugre NR, Coates TD, Nelson MD, Wood JC. PMID: 16215963.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    92. Cardiac iron determines cardiac T2*, T2, and T1 in the gerbil model of iron cardiomyopathy. Circulation. 2005 Jul 26; 112(4):535-43. Wood JC, Otto-Duessel M, Aguilar M, Nick H, Nelson MD, Coates TD, Pollack H, Moats R. PMID: 16027257.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    93. MRI R2 and R2* mapping accurately estimates hepatic iron concentration in transfusion-dependent thalassemia and sickle cell disease patients. Blood. 2005 Aug 15; 106(4):1460-5. Wood JC, Enriquez C, Ghugre N, Tyzka JM, Carson S, Nelson MD, Coates TD. PMID: 15860670.
      View in: PubMed   Mentions: 207     Fields:    Translation:Humans
    94. Physiology and pathophysiology of iron cardiomyopathy in thalassemia. Ann N Y Acad Sci. 2005; 1054:386-95. Wood JC, Enriquez C, Ghugre N, Otto-Duessel M, Aguilar M, Nelson MD, Moats R, Coates TD. PMID: 16339687.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    95. Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease. Blood. 2004 Mar 01; 103(5):1934-6. Wood JC, Tyszka JM, Carson S, Nelson MD, Coates TD. PMID: 14630822.
      View in: PubMed   Mentions: 89     Fields:    Translation:Humans
    96. Placenta growth factor activates monocytes and correlates with sickle cell disease severity. Blood. 2003 Aug 15; 102(4):1506-14. Perelman N, Selvaraj SK, Batra S, Luck LR, Erdreich-Epstein A, Coates TD, Kalra VK, Malik P. PMID: 12714517.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    97. A case of neutropenia with transient absence of neutrophil chemotaxis. Ann Allergy Asthma Immunol. 2002 May; 88(5):445-50. Sheikh J, Goldberg BJ, Kaplan MS, Staveren AM, Coates TD. PMID: 12027063.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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