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Michael Chee-Kuan Khoo, PhD

Title(s)Professor
AddressDRB 140
University Park Campus
Los Angeles CA 90089-1111
Phone+1 213 740 0347
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    Michael C.K. Khoo received his BSc(Eng) degree in Mechanical Engineering from the Imperial College of Science and Technology, University of London, in 1976, and the M.S. and Ph.D. degrees in Biomedical Engineering from Harvard University in 1977 and 1981, respectively. Before joining the faculty at USC in 1983, Dr. Khoo worked as a research engineer on a collaborative project involving the Veterans Administration Medical Center (West Roxbury), Brigham and Women's Hospital (Boston) and the Massachusetts Institute of Technology. Dr. Khoo has been the recipient of a Research Career Development Award from the National Institutes of Health and a Career Investigator Award from the American Lung Association. He is principal investigator of one of the Core Projects in the Biomedical Simulations Resource, a national center funded by the NIH National Institute of Biomedical Imaging and Bioengineering, dedicated to advancing the state of the art in biomedical modeling and computer simulation. He is also the co-principal investigator of an NIH training grant in Biomedical Imaging Informatics, and co-Director of Education and Outreach for the NSF-funded Engineering Research Center on Biomimetic Microelectronic Systems. Dr. Khoo is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE) and the Biomedical Engineering Society (BMES). He was BME Department Chair 2003-2010.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Respiratory modulation of peripheral vasoconstriction: a modeling perspective. J Appl Physiol (1985). 2019 11 01; 127(5):1177-1186. Khoo MCK, Chalacheva P. PMID: 31095465.
      View in: PubMed   Mentions:    Fields:    
    2. Sickle Cell Disease Subjects Have a Distinct Abnormal Autonomic Phenotype Characterized by Peripheral Vasoconstriction With Blunted Cardiac Response to Head-Up Tilt. Front Physiol. 2019; 10:381. Chalacheva P, Kato RM, Shah P, Veluswamy S, Denton CC, Sunwoo J, Thuptimdang W, Wood JC, Detterich JA, Coates TD, Khoo MCK. PMID: 31031633.
      View in: PubMed   Mentions:
    3. Quantifying ventilatory control stability from spontaneous sigh responses during sleep: a comparison of two approaches. Physiol Meas. 2018 11 22; 39(11):114005. Nava-Guerra L, Edwards BA, Terrill PI, Sands SA, Amin RS, Kemp JS, Khoo MCK. PMID: 30465721.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Autonomic nervous system involvement in sickle cell disease. Clin Hemorheol Microcirc. 2018; 68(2-3):251-262. Coates TD, Chalacheva P, Zeltzer L, Khoo MCK. PMID: 29614636.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Biophysical markers of the peripheral vasoconstriction response to pain in sickle cell disease. PLoS One. 2017; 12(5):e0178353. Chalacheva P, Khaleel M, Sunwoo J, Shah P, Detterich JA, Kato RM, Thuptimdang W, Meiselman HJ, Sposto R, Tsao J, Wood JC, Zeltzer L, Coates TD, Khoo MCK. PMID: 28542469.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    6. Model-Derived Markers of Autonomic Cardiovascular Dysfunction in Sleep-Disordered Breathing. Sleep Med Clin. 2016 Dec; 11(4):489-501. Khoo MCK, Chalacheva P. PMID: 28118872.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    7. Model-based stability assessment of ventilatory control in overweight adolescents with obstructive sleep apnea during NREM sleep. J Appl Physiol (1985). 2016 07 01; 121(1):185-97. Nava-Guerra L, Tran WH, Chalacheva P, Loloyan S, Joshi B, Keens TG, Nayak KS, Davidson Ward SL, Khoo MC. PMID: 27174926.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Sleep-related changes in autonomic control in obstructive sleep apnea: a model-based perspective. Respir Physiol Neurobiol. 2013 Sep 15; 188(3):267-76. Khoo MC, Blasi A. PMID: 23707878.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    9. Understanding the metabolic syndrome: a modeling perspective. IEEE Rev Biomed Eng. 2013; 6:143-55. Khoo MC, Oliveira FM, Cheng L. PMID: 23232440.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Modeling the autonomic and metabolic effects of obstructive sleep apnea: a simulation study. Front Physiol. 2011; 2:111. Cheng L, Khoo MC. PMID: 22291654.
      View in: PubMed   Mentions:
    11. An integrative model of respiratory and cardiovascular control in sleep-disordered breathing. Respir Physiol Neurobiol. 2010 Nov 30; 174(1-2):4-28. Cheng L, Ivanova O, Fan HH, Khoo MC. PMID: 20542148.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    12. Modeling of autonomic control in sleep-disordered breathing. Cardiovasc Eng. 2008 Mar; 8(1):30-41. Khoo MC. PMID: 18060581.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    13. Effects of CPAP therapy on cardiovascular variability in obstructive sleep apnea: a closed-loop analysis. Am J Physiol Heart Circ Physiol. 2002 Jan; 282(1):H110-21. Belozeroff V, Berry RB, Sassoon CS, Khoo MC. PMID: 11748054.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    14. Cardiac autonomic control in obstructive sleep apnea: effects of long-term CPAP therapy. Am J Respir Crit Care Med. 2001 Sep 01; 164(5):807-12. Khoo MC, Belozeroff V, Berry RB, Sassoon CS. PMID: 11549537.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    15. Determinants of ventilatory instability and variability. Respir Physiol. 2000 Sep; 122(2-3):167-82. Khoo MC. PMID: 10967342.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimals
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