Roger F Duncan, PhD

Title(s)Associate Professor
SchoolUSC School of Pharmacy
AddressPSC 502
Health Sciences Campus
Los Angeles CA 90089-9121
Phone+1 323 442 1449
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    Dr. Duncan received his Ph.D. from the University of Hawaii in 1978. He moved to the University of Colorado (Boulder) and the University of California (Davis) for post-doctoral research studies, before joining the University of Southern California School of Pharmacy in 1987, where he is currently an associate professor in the Department of Molecular Pharmacology.

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    HEAT STRESS EFFECTS ON PROTEIN SYNTHESIS
    NIH R29GM042644Jul 1, 1989 - Jun 30, 1994
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc Natl Acad Sci U S A. 2012 Oct 02; 109(40):16348-53. Xu S, Butkevich AN, Yamada R, Zhou Y, Debnath B, Duncan R, Zandi E, Petasis NA, Neamati N. PMID: 22988091; PMCID: PMC3479552.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    2. Rapamycin conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: implications for the mechanisms of Hsp mRNA translation. Cell Stress Chaperones. 2008; 13(2):143-55. Duncan RF. PMID: 18418733; PMCID: PMC2673887.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    3. Inhibition of Hsp90 function delays and impairs recovery from heat shock. FEBS J. 2005 Oct; 272(20):5244-56. Duncan RF. PMID: 16218955.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    4. Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress. Free Radic Biol Med. 2005 Mar 01; 38(5):631-43. Duncan RF, Peterson H, Sevanian A. PMID: 15683719.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    5. Translational regulation of Hsp90 mRNA. AUG-proximal 5'-untranslated region elements essential for preferential heat shock translation. J Biol Chem. 2004 Nov 26; 279(48):49919-30. Ahmed R, Duncan RF. PMID: 15347681.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    6. c-Jun N-terminal kinase (JNK)-mediated modulation of brain mitochondria function: new target proteins for JNK signalling in mitochondrion-dependent apoptosis. Biochem J. 2003 Jun 01; 372(Pt 2):359-69. Schroeter H, Boyd CS, Ahmed R, Spencer JP, Duncan RF, Rice-Evans C, Cadenas E. PMID: 12614194; PMCID: PMC1223409.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    7. Heme and lipid peroxides in hemoglobin-modified low-density lipoprotein mediate cell survival and adaptation to oxidative stress. Blood. 2003 Sep 01; 102(5):1732-9. Asatryan L, Ziouzenkova O, Duncan R, Sevanian A. PMID: 12750169.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    8. Oxidative stress increases eukaryotic initiation factor 4E phosphorylation in vascular cells. Biochem J. 2003 Jan 15; 369(Pt 2):213-25. Duncan RF, Peterson H, Hagedorn CH, Sevanian A. PMID: 12215171; PMCID: PMC1223074.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    9. Hepatitis C virus IRES-dependent translation is insensitive to an eIF2alpha-independent mechanism of inhibition by interferon in hepatocyte cell lines. Virology. 2002 Jun 05; 297(2):195-202. Koev G, Duncan RF, Lai MM. PMID: 12083818.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
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    NIH Funding Acknowledgment: Important - All publications resulting from the utilization of SC CTSI resources are required to credit the SC CTSI grant by including the NIH funding acknowledgment and must comply with the NIH Public Access Policy.

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