J. Perren Cobb, MD

Title(s)Professor of Surgery (Clinical Scholar)
SchoolKeck School of Medicine of Usc
Address1520 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
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    J. Perren Cobb is one of the preeminent experts in the field of critical care surgery and medicine and is director of the surgical intensive care unit at Keck Medical Center.

    Dr. Cobb's academic career started at Washington University in St. Louis, MO where he was appointed Assistant Professor in the burn, trauma, surgical critical care section of the Dept. of Surgery in 1995. Over the subsequent 14 years, Dr. Cobb achieved the rank of full professor with a joint appointment in the Department of Anesthesiology before leaving for Harvard Medical School in 2009 where he held a joint appointment in the Departments of Surgery and Anesthesiology. In 2015, Dr. Cobb moved to the west coast to assume a professorship in surgery at the Keck School of Medicine of USC.

    Among the more salient points in Dr. Cobb's impressive curriculum vitae are the pivotal and outstanding leadership roles in research he's handled masterfully and the innovative and truly game-changing contributions he's made in the field of Critical Care Surgery. He is the founding director of the United States Critical Illness and Injury Trials Group (USCIIT) and heads the USC Critical Care Institute, both of which are geared toward improving outcomes for the critically ill and injured through transformative biomedical research and performance improvement. He is single minded in his dedication to improving the delivery of care in the ICU across the nation through published chapters on Critical Care in standard textbooks and manuals and through countless national and international lectures.

    Dr. Cobb's extensive leadership in this field ensures that Keck Medical Center will continue to advance in providing excellent critical care to patients and their families.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lessons Learned From a Systematic, Hospital-Wide Implementation of the ABCDEF Bundle: A Survey Evaluation. Crit Care Explor. 2023 Nov; 5(11):e1007. Brown JC, Ding L, Querubin JA, Peden CJ, Barr J, Cobb JP. PMID: 37954897; PMCID: PMC10637401.
      View in: PubMed   Mentions:
    2. Centers for Disease Control (CDC) Wound Classification is Prognostic of 30-Day Readmission Following Surgery. World J Surg. 2023 10; 47(10):2392-2400. Yin V, Cobb JP, Wightman SC, Atay SM, Harano T, Kim AW. PMID: 37405445; PMCID: PMC10474202.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Perceived Hospital Stress, Severe Acute Respiratory Syndrome Coronavirus 2 Activity, and Care Process Temporal Variance During the COVID-19 Pandemic. Crit Care Med. 2023 04 01; 51(4):445-459. Anesi GL, Andrews A, Bai HJ, Bhatraju PK, Brett-Major DM, Broadhurst MJ, Campbell ES, Cobb JP, Gonzalez M, Homami S, Hypes CD, Irwin A, Kratochvil CJ, Krolikowski K, Kumar VK, Landsittel DP, Lee RA, Liebler JM, Lutrick K, Marts LT, Mosier JM, Mukherjee V, Postelnicu R, Rodina V, Segal LN, Sevransky JE, Spainhour C, Srivastava A, Uyeki TM, Wurfel MM, Wyles D, Evans L, Severe Acute Respiratory Infection-Preparedness (SARI-PREP) Study Group. PMID: 36790189; PMCID: PMC10012837.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    4. The impact of rounds with a psychiatry team in the intensive care unit: A prospective observational pilot study evaluating the effects on delirium incidence and outcomes. J Psychiatr Res. 2023 04; 160:64-70. Choi KJ, Tan M, Jones K, Sheski D, Cho S, Garrick T, Yau A, Solio D, Sinclair K, Cervantes E, Castillo RA, Clark D, Biswas S, Alvarez C, Grunstein I, Cobb JP, Kuza CM. PMID: 36774832.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Angiopoietin-Like4 Is a Novel Marker of COVID-19 Severity. Crit Care Explor. 2023 Jan; 5(1):e0827. Bhatraju PK, Morrell ED, Stanaway IB, Sathe NA, Srivastava A, Postelnicu R, Green R, Andrews A, Gonzalez M, Kratochvil CJ, Kumar VK, Hsiang TY, Gale M, Anesi GL, Wyles D, Broadhurst MJ, Brett-Major D, Mukherjee V, Sevransky JE, Landsittel D, Hung C, Altemeier WA, Gharib SA, Uyeki TM, Cobb JP, Liebler JM, Crosslin DR, Jarvik GP, Segal LN, Evans L, Mikacenic C, Wurfel MM. PMID: 36600780; PMCID: PMC9803343.
      View in: PubMed   Mentions: 7  
    6. Crisis Triage in the Era of COVID-19: Old Tools, New Approaches, and Unanswered Questions. Crit Care Med. 2023 01 01; 51(1):148-150. Harris GH, Cobb JP, Evans L. PMID: 36519991; PMCID: PMC9749941.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. An Electronic Data Capture Tool for Data Collection During Public Health Emergencies: Development and Usability Study. JMIR Hum Factors. 2022 Jun 09; 9(2):e35032. Brown J, Bhatnagar M, Gordon H, Goodner J, Cobb JP, Lutrick K. PMID: 35679114; PMCID: PMC9227656.
      View in: PubMed   Mentions:    Fields:    
    8. Improving ABCDEF Bundle Compliance and Clinical Outcomes in the ICU: Randomized Control Trial to Assess the Impact of Performance Measurement, Feedback, and Data Literacy Training. Crit Care Explor. 2022 Apr; 4(4):e0679. Brown JC, Querubin JA, Ding L, Mack WJ, Chen-Chan K, Perez F, Barr J, Peden CJ, Cobb JP. PMID: 35474653; PMCID: PMC9029907.
      View in: PubMed   Mentions: 4  
    9. Use of an extended KDIGO definition to diagnose acute kidney injury in patients with COVID-19: A multinational study using the ISARIC-WHO clinical characterisation protocol. PLoS Med. 2022 04; 19(4):e1003969. Wainstein M, MacDonald S, Fryer D, Young K, Balan V, Begum H, Burrell A, Citarella BW, Cobb JP, Kelly S, Kennon K, Lee J, Merson L, Murthy S, Nichol A, Semple MG, Strudwick S, Webb SA, Rossignol P, Claure-Del Granado R, Shrapnel S, ISARIC Clinical Characterisation Group. PMID: 35442972; PMCID: PMC9067700.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    10. Critical Care Response During the COVID-19 Pandemic. Crit Care Clin. 2022 Jul; 38(3):623-637. Rednor S, Eisen LA, Cobb JP, Evans L, Coopersmith CM. PMID: 35667747; PMCID: PMC8747943.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
    11. ICU Resource Limitations During Peak Seasonal Influenza: Results of a 2018 National Feasibility Study. Crit Care Explor. 2022 Jan; 4(1):e0606. Lane CJ, Bhatnagar M, Lutrick K, Maves RC, Weiner D, Rios Olvera D, Uyeki TM, Cobb JP, Brown JC. PMID: 35018345; PMCID: PMC8735785.
      View in: PubMed   Mentions: 4  
    12. Cognitive task analysis-based training in surgery: a meta-analysis. BJS Open. 2021 11 09; 5(6). Edwards TC, Coombs AW, Szyszka B, Logishetty K, Cobb JP. PMID: 34904648; PMCID: PMC8669793.
      View in: PubMed   Mentions: 5  Translation:Humans
    13. Complications Following Brachial Arterial Catheterization in the Surgical Intensive Care Unit. Am Surg. 2020 Oct; 86(10):1260-1263. Schellenberg M, Hawley L, Biswas S, Clark DH, Cobb JP. PMID: 33106000.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Fluid Resuscitation and Vasopressors in Septic Shock: The Importance of Filling the Tank While Squeezing the Pipes. Crit Care Med. 2020 10; 48(10):1533-1535. Schellenberg M, Cobb JP. PMID: 32925261.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. The pharmacist's role in disaster research response. Am J Health Syst Pharm. 2020 06 23; 77(13):1054-1059. Edwards CJ, Miller A, Cobb JP, Erstad BL. PMID: 32350533; PMCID: PMC7455762.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Development of a Process and Infrastructure to Outreach Stakeholders for Capturing Healthcare System Stress in Emergency Response Situations. Online J Public Health Inform. 2019; 11(2):e2. Read T, White E, Cobb JP, Mar P, Shanmugam M, Rocha RA, Rossetti SC. PMID: 31632596; PMCID: PMC6788903.
      View in: PubMed   Mentions:
    17. Clinical Investigation During Public Health Emergencies: The Resilience Intelligence Network. Am J Public Health. 2019 09; 109(S4):S268-S270. Cobb JP. PMID: 31505157; PMCID: PMC6737823.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
    18. Nosocomial Pneumonia in the ICU: Still More Questions Than Answers. Crit Care Med. 2019 03; 47(3):472-473. Schellenberg M, Cobb JP. PMID: 30768505.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Variability in intensive care unit length of stay after liver transplant: Determinants and potential opportunities for improvement. J Crit Care. 2019 04; 50:296-302. Pita A, Nguyen B, Rios D, Maalouf N, Lo M, Genyk Y, Sher L, Cobb JP. PMID: 30677626.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    20. Balanced blood product transfusion during liver transplantation. Clin Transplant. 2018 03; 32(3):e13191. Hogen R, Dhanireddy K, Clark D, Biswas S, DiNorcia J, Brown N, Yee J, Cobb JP, Strumwasser A. PMID: 29314246.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    21. Survey of Annual Staffing Workloads for Adult Critical Care Physicians Working in the United States. Ann Am Thorac Soc. 2016 05; 13(5):751-3. Sevransky JE, Chai ZJ, Cotsonis GA, Cobb JP, Pastores SM. PMID: 27144800; PMCID: PMC5018891.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    22. Development of a Core Clinical Dataset to Characterize Serious Illness, Injuries, and Resource Requirements for Acute Medical Responses to Public Health Emergencies. Crit Care Med. 2015 Nov; 43(11):2403-8. Murphy DJ, Rubinson L, Blum J, Isakov A, Bhagwanjee S, Cairns CB, Cobb JP, Sevransky JE, United States Critical Illness and Injury Trials Group–Program for Emergency Preparedness. PMID: 26308434.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    23. Global participation in core data sets for emerging pathogens. Am J Respir Crit Care Med. 2015 Apr 01; 191(7):728-30. Carson SS, Fowler RA, Cobb JP, Arabi YM, Ingbar DH, ATS Taskforce on Emerging Pathogens. PMID: 25830518.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
    24. Plasma 25-Hydroxyvitamin D Levels at Initiation of Care and Duration of Mechanical Ventilation in Critically Ill Surgical Patients. JPEN J Parenter Enteral Nutr. 2016 Feb; 40(2):273-8. Quraishi SA, McCarthy C, Blum L, Cobb JP, Camargo CA. PMID: 25564428; PMCID: PMC4492899.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    25. Clustering analysis to identify distinct spectral components of encephalogram burst suppression in critically ill patients. Annu Int Conf IEEE Eng Med Biol Soc. 2015; 2015:7258-61. Zhou DW, Westover MB, McClain LM, Nagaraj SB, Bajwa EK, Quraishi SA, Akeju O, Cobb JP, Purdon PL. PMID: 26737967; PMCID: PMC4870011.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Advanced imaging use in intensive care units has decreased, resulting in lower charges without negative effects on patient outcomes. J Crit Care. 2015 Jun; 30(3):460-4. Lee J, Geyer B, Naraghi L, Kaafarani HM, Eikermann M, Yeh DD, Bajwa EK, Cobb JP, Raja AS. PMID: 25596998.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Assessment of satisfaction with care among family members of survivors in a neuroscience intensive care unit. J Neurosci Nurs. 2014 Apr; 46(2):106-16. Hwang DY, Yagoda D, Perrey HM, Tehan TM, Guanci M, Ananian L, Currier PF, Cobb JP, Rosand J. PMID: 24556658; PMCID: PMC4401420.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    28. Consistency of communication among intensive care unit staff as perceived by family members of patients surviving to discharge. J Crit Care. 2014 Feb; 29(1):134-8. Hwang DY, Yagoda D, Perrey HM, Tehan TM, Guanci M, Ananian L, Currier PF, Cobb J, Rosand J. PMID: 24475496.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    29. Anxiety and depression symptoms among families of adult intensive care unit survivors immediately following brief length of stay. J Crit Care. 2014 Apr; 29(2):278-82. Hwang DY, Yagoda D, Perrey HM, Currier PF, Tehan TM, Guanci M, Ananian L, Cobb JP, Rosand J. PMID: 24411107.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
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