Sean Conor Wightman

Title(s)Associate Professor of Clinical Surgery
SchoolKeck School of Medicine of Usc
Address1520 San Pablo St.
Health Sciences Campus
Los Angeles CA 90033
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    1. Decision-Making in Surgical Patients: Discarding "Heroic Measures" in Favor of Goal-Oriented Care at the End of Life. J Surg Oncol. 2025 May 15. Yu E, Shakhsheer BA, Wightman SC. PMID: 40375489.
      View in: PubMed   Mentions:    Fields:    
    2. Performance of the Charlson and Elixhauser Comorbidity Index Varies With the Type of Minimally Invasive Thoracic Surgery. World J Surg. 2025 06; 49(6):1418-1431. Kim AT, Ding L, Udelsman BV, Atay SM, Wightman SC, Harano T, Rosenberg GM, Blasberg JD, Boffa DJ, Kim AW. PMID: 40261152.
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    3. An Ethical Framework for Cost-Conscious Surgical Practice. Ann Surg. 2025 Feb 13. Phelps HM, Wightman SC, Shakhsheer BA. PMID: 39945103.
      View in: PubMed   Mentions:    Fields:    
    4. Impact of Ex Vivo Lung Perfusion on Inpatient Cost: A Propensity Score-Matched Analysis of the US Nationwide Healthcare Cost and Utilization Project Database. Clin Transplant. 2025 Feb; 39(2):e70096. Yin V, Atay SM, Rodman JCS, Wightman SC, Rosenberg GM, Udelsman BV, Kim AW, Harano T. PMID: 39876610.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Invited Commentary: Moving the Needle on Second-Victim Syndrome: From Acknowledgment to Understanding to Action. J Am Coll Surg. 2025 Feb 01; 240(2):227-228. Shakhsheer BA, Wightman SC. PMID: 39186059.
      View in: PubMed   Mentions:    Fields:    
    6. Living on the edge: Role of adjuvant therapy after resection of primary lung cancer within 2 millimeters of a T-stage cutoff. J Thorac Cardiovasc Surg. 2025 May; 169(5):1338-1345.e15. Udelsman BV, Bedrosian CK, Kawaguchi ES, Ding L, Wallace WD, Rosenberg G, Harano T, Wightman S, Atay S, Kim AW, Woodard G. PMID: 39521371; PMCID: PMC12034478.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Outcomes of single-lung retransplantation after double-lung transplantation. J Thorac Cardiovasc Surg. 2025 May; 169(5):1398-1406.e2. Yin V, Rodman JCS, Atay SM, Wightman SC, Rosenberg GM, Udelsman BV, Ganesh S, Chung P, Kim AW, Harano T. PMID: 39357566.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Thrombolysis and Surgical Decompression for Venous Thoracic Outlet Syndrome. J Surg Res. 2024 Nov; 303:134-140. Yin V, Udelsman BV, Kim AT, Wightman SC, Harano T, Rosenberg GM, Atay SM, Kim AW. PMID: 39332077.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Right Upper Lobe Large Cell Neuroendocrine Carcinoma with Atypical Carcinoid Features: Case Report. Case Rep Oncol. 2024 Jan-Dec; 17(1):1042-1049. Lee Y, Rodrigs R, Wallace WD, Wightman SC. PMID: 39474548; PMCID: PMC11521487.
      View in: PubMed   Mentions:
    10. Ethical considerations in lung re-transplantation. Curr Opin Organ Transplant. 2024 Dec 01; 29(6):388-393. Lester LA, Huang VP, Wightman SC, Rosenberg GM. PMID: 39115394.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Initial management and outcomes of nonmalignant esophageal perforations: A Nationwide Inpatient Sample analysis. Surgery. 2024 10; 176(4):1115-1122. Ashbrook MJ, Theeuwen HA, Cheng V, Harano T, Wightman SC, Atay SM, Rosenberg GM, Udelsman BV, Kim AW. PMID: 39025691.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Alternative discharge destination following lobectomy: Analysis of a national quality improvement database. JTCVS Open. 2024 Oct; 21:349-357. Yin V, Wightman SC, Harano T, Atay SM, Kim AW. PMID: 39534327; PMCID: PMC11551280.
      View in: PubMed   Mentions:
    13. Esophageal perforation secondary to esophageal gastrointestinal stromal tumor. JTCVS Tech. 2024 Oct; 27:172-175. Sheth M, Atay SM, Wightman SC, Rosenberg GM, Udelsman BV, Kim AW, Harano T. PMID: 39478888; PMCID: PMC11518882.
      View in: PubMed   Mentions:
    14. The Society of Thoracic Surgeons Expert Consensus Document on the Surgical Management of Thymomas. Ann Thorac Surg. 2024 Nov; 118(5):975-1004. Liou DZ, Berry MF, Brown LM, Demmy TL, Huang J, Khullar OV, Padda SK, Shah RD, Taylor MD, Toker SA, Weiss E, Wightman SC, Worrell SG, Hayanga JWA. PMID: 38718878.
      View in: PubMed   Mentions: 2     Fields:    
    15. Decision-Making in Surgery. Ann Thorac Surg. 2024 06; 117(6):1087-1094. Angelos P, Taylor LJ, Roggin K, Schwarze ML, Vaughan LM, Wightman SC, Sade RM. PMID: 38242340.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Ethical Concerns Regarding the Timing of Written Consent. J Clin Ethics. 2024; 35(4):274-283. Wightman SC, Yin V, Hershenhouse JS, Abebe TB, Ding L, Atay SM, Harano T, Kim AW, Pagteilan JN, Uppal A, Shakhsheer BA. PMID: 39540639.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. Delayed esophagectomy for adenocarcinoma is associated with a negative impact on long-term survival and an increased risk of perioperative morbidity. J Surg Oncol. 2024 Mar; 129(3):592-600. Huang VP, Ding L, Kim AW, Wightman SC, Atay SM. PMID: 37986276.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Association between underweight status and chylothorax after esophagectomy for esophageal cancer: A propensity score-matched analysis. JTCVS Open. 2024 Feb; 17:322-335. Yin V, Kim AT, Wightman SC, Harano T, Atay SM, Kim AW. PMID: 38420538; PMCID: PMC10897597.
      View in: PubMed   Mentions: 1  
    19. Early outcomes of lung transplantation with lung allografts from coronavirus disease 2019 (COVID-19)-positive donors. J Thorac Cardiovasc Surg. 2024 Jun; 167(6):1955-1964.e3. Jeon JH, Harano T, Rodman JCS, Sheth M, Wightman SC, Atay SM, Kim AW. PMID: 37625616.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. Centers for Disease Control (CDC) Wound Classification is Prognostic of 30-Day Readmission Following Surgery. World J Surg. 2023 10; 47(10):2392-2400. Yin V, Cobb JP, Wightman SC, Atay SM, Harano T, Kim AW. PMID: 37405445; PMCID: PMC10474202.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    21. Delays to surgery and worse outcomes: The compounding effects of social determinants of health in non-small cell lung cancer. JTCVS Open. 2023 Sep; 15:468-478. Ashrafi A, Ding L, Atay SM, Wightman SC, Harano T, Kim AW. PMID: 37808033; PMCID: PMC10556947.
      View in: PubMed   Mentions:
    22. Longer hospitalizations, more complications, and greater readmissions for patients with comorbid psychiatric disorders undergoing pulmonary lobectomy. J Thorac Cardiovasc Surg. 2024 04; 167(4):1502-1511.e11. Kim AT, Ding L, Lee HB, Ashbrook MJ, Ashrafi A, Wightman SC, Atay SM, David EA, Harano T, Kim AW. PMID: 37245626.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Repair of Anterior Tracheal Defect by Trans-Tracheostomy Placement of Acellular Dermal Matrix. Laryngoscope. 2023 08; 133(8):1961-1963. Youn S, Ge M, O'Dell K, Wightman S, Kung R. PMID: 36815616.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    24. Adjuvant chemotherapy, not radiotherapy, prolongs survival for node-negative non-small cell lung cancer with positive surgical margins. JTCVS Open. 2023 Jun; 14:472-482. Ashrafi A, Yu J, Kim AT, Ye JC, David EA, Wightman SC, Atay SM, Harano T, Kim AW. PMID: 37425454; PMCID: PMC10328815.
      View in: PubMed   Mentions:
    25. Estimating revenue, costs, and operating margin of any hospital-based thoracic surgery practice using a novel financial model. J Thorac Cardiovasc Surg. 2023 09; 166(3):690-698.e1. Ashrafi A, Atay SM, Wightman SC, Harano T, Kim AW. PMID: 36934070.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Heart transplantation for pediatric foreign nationals in the United States. Clin Transplant. 2023 02; 37(2):e14900. Harano T, Sheth M, Sasaki K, Yu J, Wightman SC, Atay SM, Sainathan S, Kim AW. PMID: 36587308.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Safety and feasibility of minimally invasive lobectomy after neoadjuvant immunotherapy for non-small cell lung cancer. J Thorac Cardiovasc Surg. 2023 08; 166(2):347-355.e2. Mathey-Andrews C, McCarthy M, Potter AL, Beqari J, Wightman SC, Liou D, Raman V, Jeffrey Yang CF. PMID: 36653251; PMCID: PMC10272281.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    28. Surgical informed consent: new challenges. Curr Probl Surg. 2023 02; 60(2):101258. Hoppenot C, Bryan AF, Wightman SC, Yin V, Ferguson BD, Bidadi S, Mitchell MB, Langerman AJ, Angelos P, Singh P. PMID: 36813352.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. Benefit of adjuvant chemotherapy for resected pathologic N1 non-small cell lung cancer is unrecognized: A subgroup analysis of the JBR10 trial. Semin Thorac Cardiovasc Surg. 2024; 36(2):261-270. Toubat O, Ding L, Ding K, Wightman SC, Atay SM, Harano T, Kim AW, David EA. PMID: 36272526.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    30. Shared Consent: Acknowledging the Subjectivity of Surgical Decision-making. Ann Surg. 2023 05 01; 277(5):e979-e980. Kepper PJ, Wightman SC, Shakhsheer BA. PMID: 35993554.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    31. Ethical issues surrounding mechanical circulatory support. Int Anesthesiol Clin. 2022 10 01; 60(4):64-71. Yin V, Shakhsheer BA, Angelos P, Wightman SC. PMID: 35960690.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    32. Invited Commentary: Unprofessionalism Is a Contagion: Burnout Prevention Is the Cure. J Am Coll Surg. 2022 09 01; 235(3):548-549. Donohue SJ, Wightman SC. PMID: 35588505.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    33. Adjuvant chemotherapy for visceral pleural invasion in 3-4-cm non-small-cell lung cancer improves survival. Eur J Cardiothorac Surg. 2022 06 15; 62(1). Wightman SC, Lee JY, Ding L, Atay SM, Shemanski KA, McFadden PM, David EA, Kim AW. PMID: 35325098.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    34. Surgical decision-making in advanced-stage non-small cell lung cancer is influenced by more than just guidelines. JTCVS Open. 2022 Sep; 11:286-299. Peng T, Farias AJ, Shemanski KA, Kim AW, Wightman SC, Atay SM, Canter RJ, David EA. PMID: 36172417; PMCID: PMC9510805.
      View in: PubMed   Mentions: 2  
    35. Lobectomy offers improved survival outcomes relative to segmentectomy for >2 but ≤4 cm non-small cell lung cancer tumors. JTCVS Open. 2022 Jun; 10:356-367. Peng T, Wightman SC, Ding L, Lieu DK, Atay SM, David EA, Kim AW. PMID: 36004221; PMCID: PMC9390142.
      View in: PubMed   Mentions: 5  
    36. Patterns of Use of Stereotactic Body Radiation Therapy Compared With Surgery for Definitive Treatment of Primary Early-stage Non-small Cell Lung Cancer. Am J Clin Oncol. 2022 04 01; 45(4):146-154. Jang JK, Atay SM, Ding L, David EA, Wightman SC, Kim AW, Ye JC. PMID: 35320815; PMCID: PMC8971891.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. The Perfect is the Enemy of the Good. Ann Thorac Surg. 2022 09; 114(3):940. Wightman SC, David EA. PMID: 35346630.
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    38. Adhering to guideline concordant care improves survival among the different subtypes of T3 N2 non-small cell lung cancer. JTCVS Open. 2022 Jun; 10:384-392. Wang JC, Ding L, David EA, Atay SM, Wightman SC, McFadden PM, Harano T, Kim AW. PMID: 36004267; PMCID: PMC9390621.
      View in: PubMed   Mentions: 1  
    39. Esophagectomy for Permanent Mesh Migration After Transthoracic Hiatal Hernia Repair. Ann Thorac Surg. 2022 08; 114(2):e89-e91. Yin V, Pagteilan J, Atay SM, David EA, Kim AW, Wightman SC. PMID: 34914935.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    40. Training residents in robotic thoracic surgery. J Thorac Dis. 2021 Oct; 13(10):6169-6178. Alicuben ET, Wightman SC, Shemanski KA, David EA, Atay SM, Kim AW. PMID: 34795968; PMCID: PMC8575838.
      View in: PubMed   Mentions: 5  
    41. Informed Decision-Making: Knowing Is Not the Same as Doing. J Am Coll Surg. 2021 10; 233(4):578-579. Wightman SC, Shakhsheer BA. PMID: 34563331.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Primary signet ring cell histology does not portend worse survival for early stage lung cancer following lobectomy. Asian Cardiovasc Thorac Ann. 2022 Feb; 30(2):185-189. Peng T, Yau A, Ding L, David EA, Wightman SC, Atay SM, Kim AW. PMID: 34549632.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. Enhanced Recovery After Surgery Protocol Minimizes Intensive Care Unit Utilization and Improves Outcomes Following Pulmonary Resection. World J Surg. 2021 10; 45(10):2955-2963. Peng T, Shemanski KA, Ding L, David EA, Kim AW, Kim M, Lieu DK, Wightman SC, Zhao J, Atay SM. PMID: 34350489; PMCID: PMC8336670.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    44. Exploring the Potential Different Outcomes Associated With the Different Phenotypes Under the Shared Pathologic T3N0 Designation. JTO Clin Res Rep. 2021 Jun; 2(6):100186. Peng T, Wightman SC, Ding L, Atay SM, Alicuben ET, David EA, Kim AW. PMID: 34590031; PMCID: PMC8474447.
      View in: PubMed   Mentions:
    45. Regional Variation in Treatment for Highest-Risk Patients With Non-Small Cell Lung Cancer. Ann Thorac Surg. 2022 04; 113(4):1282-1290. Bick KJ, Ding L, Ebner PJ, Kim AW, Atay SM, Wightman SC, McFadden PM, Farias AJ, David EA. PMID: 33964260.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    46. Differential outcomes of residual disease in surgically-resected non-small cell lung cancer and the importance of guideline-concordant adjuvant therapy. J Thorac Dis. 2021 May; 13(5):2896-2909. Lieu DK, Ding L, David EA, Wightman SC, Atay SM, McFadden PM, Kim AW. PMID: 34164181; PMCID: PMC8182525.
      View in: PubMed   Mentions:
    47. Value of a Multidisciplinary Team Approach to Treatment of Emphysema. Thorac Surg Clin. 2021 May; 31(2):171-175. Wightman SC, McKenna RJ. PMID: 33926670.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    48. Obtaining Consent in the Preoperative Area: We Can Do Better. J Am Coll Surg. 2021 08; 233(2):314-315. Wightman SC, Shakhsheer BA. PMID: 33878453.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Gender representation among leadership at national and regional cardiothoracic surgery organizational annual meetings. J Thorac Cardiovasc Surg. 2021 Mar; 161(3):733-744. Shemanski KA, Ding L, Kim AW, Blackmon SH, Wightman SC, Atay SM, Starnes VA, David EA. PMID: 33431207.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    50. Adjuvant Chemotherapy Improves Survival in pN-positive Clinical Stage IIIA Non-Small Cell Lung Cancer After Neoadjuvant Therapy and Resection. Ann Thorac Surg. 2021 07; 112(1):197-205. Atay SM, Amini M, Ding L, David EA, Mcfadden PM, Wightman SC, Kim AW. PMID: 33121965.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    51. Understanding thoracic surgeons' perceptions of administrative database analyses and guidelines in clinical decision-making. J Thorac Cardiovasc Surg. 2021 Mar; 161(3):807-816.e1. Shemanski KA, Farias A, Lieu D, Kim AW, Wightman S, Atay SM, Canter RJ, David EA. PMID: 33139063.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    52. Trends in pneumonectomy for treatment of small-cell lung cancer. Asian Cardiovasc Thorac Ann. 2020 Nov; 28(9):583-591. Zhao J, Nguyen A, Ding L, David EA, Atay SM, Wightman SC, McFadden PM, Kim AW. PMID: 32878450.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    53. Commentary: A breath of fresh air for thoracic surgeons in the coronavirus disease 2019 (COVID-19) era. JTCVS Tech. 2020 Sep; 3:415-416. Wightman SC, David EA. PMID: 32996904; PMCID: PMC7305709.
      View in: PubMed   Mentions:
    54. Sequence of biologic therapies and surgery affects survival in non-small cell lung cancer. J Surg Oncol. 2020 Aug; 122(2):320-327. Xu E, David EA, Ding L, Atay SM, McFadden PM, Wightman SC, Kim AW. PMID: 32436293.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    55. Commentary: When less is more for lung cancers. J Thorac Cardiovasc Surg. 2021 05; 161(5):1650-1651. Wightman SC, Kim AW. PMID: 32711972.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    56. Spontaneous Bleeding From Multiple Intercostal Arteries in a Patient With Coarctation of the Aorta. Ann Thorac Surg. 2020 08; 110(2):e95-e97. Wightman SC, Wang Y, Rohr AM, Greene CL, Hwang GL, Watkins AC, Lui NS. PMID: 32035043.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    57. A systematic review of paraneoplastic syndromes associated with thymoma: Treatment modalities, recurrence, and outcomes in resected cases. J Thorac Cardiovasc Surg. 2020 Jul; 160(1):306-314.e14. Zhao J, Bhatnagar V, Ding L, Atay SM, David EA, McFadden PM, Stamnes S, Lechtholz-Zey E, Wightman SC, Detterbeck FC, Kim AW. PMID: 31982129.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    58. Commentary: This Story About Three Pigs Is No Fable. Semin Thorac Cardiovasc Surg. 2020; 32(2):367-368. Wightman SC, Kim AW. PMID: 31760141.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    59. Non-Myasthenia Gravis Immune Syndromes and the Thymus: Is There a Role for Thymectomy? Thorac Surg Clin. 2019 May; 29(2):215-225. Wightman SC, Shrager JB. PMID: 30928003.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    60. Extremes of body mass index and postoperative complications after esophagectomy. Dis Esophagus. 2017 May 01; 30(5):1-6. Wightman SC, Posner MC, Patti MG, Ganai S, Watson S, Prachand V, Ferguson MK. PMID: 28375438.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    61. Ethical aspects of a video-assisted thoracoscopic surgery practice. J Vis Surg. 2017; 3:8. Wightman SC, Angelos P. PMID: 29078571; PMCID: PMC5637564.
      View in: PubMed   Mentions:
    62. An organized approach to complex ethical cases on a surgical service. World J Surg. 2014 Jul; 38(7):1664-7. Wightman SC, Angelos P. PMID: 24740838.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    63. Prognostic value of xanthine oxidoreductase expression in patients with non-small cell lung cancer. Lung Cancer. 2011 Feb; 71(2):186-90. Kim AW, Batus M, Myint R, Fidler MJ, Basu S, Bonomi P, Faber LP, Wightman SC, Warren WH, McIntire M, Arvanitis LD, Gattuso P, Xu X, Liptay MJ. PMID: 20570389.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    64. An unusual case of Aspergillus fibrosing mediastinitis. Ann Thorac Surg. 2009 Oct; 88(4):1352-4. Wightman SC, Kim AW, Proia LA, Faber LP, Gattuso P, Warren WH, Liptay MJ. PMID: 19766844.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    65. Pneumonectomy after chemoradiation therapy for non-small cell lung cancer: does "side" really matter? Ann Thorac Surg. 2009 Sep; 88(3):937-43; discussion 944. Kim AW, Faber LP, Warren WH, Basu S, Wightman SC, Weber JA, Bonomi P, Liptay MJ. PMID: 19699924.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
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